,question,answer,question_new
99,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RP11-141B14.1 expression is measured. Determine whether RP11-141B14.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RP11-141B14.1 expression is measured. Determine whether RP11-141B14.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of GUSB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of GUSB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and CD46 expression is quantified. Does this perturbation result in a significant change in CD46 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and CD46 expression is quantified. Does this perturbation result in a significant change in CD46 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in PCF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in PCF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1843,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and OR2T6 expression is observed. Does this perturbation lead to a significant difference in OR2T6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and OR2T6 expression is observed. Does this perturbation lead to a significant difference in OR2T6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of ZCCHC11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of ZCCHC11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in PGM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in PGM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of RP11-157D23.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of RP11-157D23.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of GALNT7. Does perturbing FECH lead to a significant change in GALNT7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of GALNT7. Does perturbing FECH lead to a significant change in GALNT7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of CD9. Does perturbing SRPR lead to a significant change in CD9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of CD9. Does perturbing SRPR lead to a significant change in CD9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of MT2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of MT2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and RNF139-AS1 expression is measured. Determine whether RNF139-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and RNF139-AS1 expression is measured. Determine whether RNF139-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of FCGRT. Does this perturbation cause a significant change in FCGRT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of FCGRT. Does this perturbation cause a significant change in FCGRT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of QSER1. Does this perturbation cause a significant change in QSER1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of QSER1. Does this perturbation cause a significant change in QSER1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and GMEB1 expression is quantified. Does this perturbation result in a significant change in GMEB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and GMEB1 expression is quantified. Does this perturbation result in a significant change in GMEB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of ACE. Does perturbing FARSB lead to a significant change in ACE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of ACE. Does perturbing FARSB lead to a significant change in ACE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and DOCK11 expression is quantified. Does this perturbation result in a significant change in DOCK11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and DOCK11 expression is quantified. Does this perturbation result in a significant change in DOCK11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
168,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor RIMS3 expression. Decide whether this perturbation leads to a significant alteration in RIMS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor RIMS3 expression. Decide whether this perturbation leads to a significant alteration in RIMS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3750,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of KIAA1432 is measured. Does this perturbation cause a significant change in KIAA1432 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of KIAA1432 is measured. Does this perturbation cause a significant change in KIAA1432 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of PLA2G15. Does perturbing HYOU1 lead to a significant change in PLA2G15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of PLA2G15. Does perturbing HYOU1 lead to a significant change in PLA2G15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of TKTL1 is measured. Determine whether TKTL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of TKTL1 is measured. Determine whether TKTL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of RP11-430H10.1. Does perturbing P4HB lead to a significant change in RP11-430H10.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of RP11-430H10.1. Does perturbing P4HB lead to a significant change in RP11-430H10.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2313,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and ANKLE2 expression is observed. Does this perturbation lead to a significant difference in ANKLE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and ANKLE2 expression is observed. Does this perturbation lead to a significant difference in ANKLE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and LAMP2 expression is measured. Determine whether LAMP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and LAMP2 expression is measured. Determine whether LAMP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and MARCH8 expression is quantified. Does this perturbation result in a significant change in MARCH8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and MARCH8 expression is quantified. Does this perturbation result in a significant change in MARCH8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of GATA3 is measured. Determine whether GATA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of GATA3 is measured. Determine whether GATA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4213,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and CD46 expression is observed. Does this perturbation lead to a significant difference in CD46 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and CD46 expression is observed. Does this perturbation lead to a significant difference in CD46 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in RP11-90P5.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in RP11-90P5.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of NINJ2. Does perturbing SLC39A7 lead to a significant change in NINJ2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of NINJ2. Does perturbing SLC39A7 lead to a significant change in NINJ2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of KIAA1432 is measured. Determine whether KIAA1432 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of KIAA1432 is measured. Determine whether KIAA1432 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and ATP6V1B2 expression is quantified. Does this perturbation result in a significant change in ATP6V1B2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and ATP6V1B2 expression is quantified. Does this perturbation result in a significant change in ATP6V1B2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of AC104532.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of AC104532.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of RP11-334C17.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of RP11-334C17.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of PCF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of PCF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3688,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor SLC27A2 expression. Decide whether this perturbation leads to a significant alteration in SLC27A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor SLC27A2 expression. Decide whether this perturbation leads to a significant alteration in SLC27A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
12,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and P4HA2 expression is quantified. Does this perturbation result in a significant change in P4HA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and P4HA2 expression is quantified. Does this perturbation result in a significant change in P4HA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2000,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of C1GALT1 is measured. Does this perturbation cause a significant change in C1GALT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of C1GALT1 is measured. Does this perturbation cause a significant change in C1GALT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of NINJ2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of NINJ2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and MARCH8 expression is measured. Determine whether MARCH8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and MARCH8 expression is measured. Determine whether MARCH8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and RP11-471M2.3 expression is measured. Determine whether RP11-471M2.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and RP11-471M2.3 expression is measured. Determine whether RP11-471M2.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of ATP6AP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of ATP6AP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of LINC00862. Does this perturbation cause a significant change in LINC00862 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of LINC00862. Does this perturbation cause a significant change in LINC00862 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of TAGLN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of TAGLN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of TTC18. Does perturbing TIMM44 lead to a significant change in TTC18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of TTC18. Does perturbing TIMM44 lead to a significant change in TTC18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3748,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor KIAA0922 expression. Decide whether this perturbation leads to a significant alteration in KIAA0922 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor KIAA0922 expression. Decide whether this perturbation leads to a significant alteration in KIAA0922 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and RP11-789C1.1 expression is measured. Determine whether RP11-789C1.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and RP11-789C1.1 expression is measured. Determine whether RP11-789C1.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4303,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and GCKR expression is observed. Does this perturbation lead to a significant difference in GCKR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and GCKR expression is observed. Does this perturbation lead to a significant difference in GCKR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and CTBS expression is measured. Determine whether CTBS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and CTBS expression is measured. Determine whether CTBS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
72,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and CEBPG expression is quantified. Does this perturbation result in a significant change in CEBPG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and CEBPG expression is quantified. Does this perturbation result in a significant change in CEBPG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1123,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and RP11-640M9.1 expression is observed. Does this perturbation lead to a significant difference in RP11-640M9.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and RP11-640M9.1 expression is observed. Does this perturbation lead to a significant difference in RP11-640M9.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and PCK2 expression is quantified. Does this perturbation result in a significant change in PCK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and PCK2 expression is quantified. Does this perturbation result in a significant change in PCK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of SERPING1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of SERPING1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and RP11-132A1.4 expression is measured. Determine whether RP11-132A1.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and RP11-132A1.4 expression is measured. Determine whether RP11-132A1.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in FYTTD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in FYTTD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
250,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of LINC00657 is measured. Does this perturbation cause a significant change in LINC00657 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of LINC00657 is measured. Does this perturbation cause a significant change in LINC00657 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4838,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor RP11-390B4.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-390B4.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor RP11-390B4.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-390B4.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of RP11-38P22.2 is measured. Determine whether RP11-38P22.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of RP11-38P22.2 is measured. Determine whether RP11-38P22.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of SETD5-AS1. Does perturbing UFL1 lead to a significant change in SETD5-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of SETD5-AS1. Does perturbing UFL1 lead to a significant change in SETD5-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3213,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and TTC32 expression is observed. Does this perturbation lead to a significant difference in TTC32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and TTC32 expression is observed. Does this perturbation lead to a significant difference in TTC32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3940,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ROBO1 is measured. Does this perturbation cause a significant change in ROBO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ROBO1 is measured. Does this perturbation cause a significant change in ROBO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and PLB1 expression is quantified. Does this perturbation result in a significant change in PLB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and PLB1 expression is quantified. Does this perturbation result in a significant change in PLB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1680,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of EP300 is measured. Does this perturbation cause a significant change in EP300 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of EP300 is measured. Does this perturbation cause a significant change in EP300 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and RP11-3D4.3 expression is quantified. Does this perturbation result in a significant change in RP11-3D4.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and RP11-3D4.3 expression is quantified. Does this perturbation result in a significant change in RP11-3D4.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3888,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor RP11-573D15.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-573D15.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor RP11-573D15.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-573D15.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and NOXA1 expression is measured. Determine whether NOXA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and NOXA1 expression is measured. Determine whether NOXA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of HIST1H2AM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of HIST1H2AM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and PTPN11 expression is measured. Determine whether PTPN11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and PTPN11 expression is measured. Determine whether PTPN11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of VPS41 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of VPS41 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and PRRC2B expression is measured. Determine whether PRRC2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and PRRC2B expression is measured. Determine whether PRRC2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in LTB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in LTB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of GMEB1 is measured. Determine whether GMEB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of GMEB1 is measured. Determine whether GMEB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4238,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor RP11-666A20.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-666A20.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor RP11-666A20.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-666A20.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2050,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of EP300 is measured. Does this perturbation cause a significant change in EP300 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of EP300 is measured. Does this perturbation cause a significant change in EP300 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of RP11-430H10.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of RP11-430H10.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of NRIP1. Does perturbing EIF2S1 lead to a significant change in NRIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of NRIP1. Does perturbing EIF2S1 lead to a significant change in NRIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
858,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor ATF6 expression. Decide whether this perturbation leads to a significant alteration in ATF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor ATF6 expression. Decide whether this perturbation leads to a significant alteration in ATF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4900,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of CHD3 is measured. Does this perturbation cause a significant change in CHD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of CHD3 is measured. Does this perturbation cause a significant change in CHD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of TRPM4 is measured. Determine whether TRPM4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of TRPM4 is measured. Determine whether TRPM4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and RP11-212I21.4 expression is quantified. Does this perturbation result in a significant change in RP11-212I21.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and RP11-212I21.4 expression is quantified. Does this perturbation result in a significant change in RP11-212I21.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of SLC26A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of SLC26A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of DDX3X is measured. Determine whether DDX3X shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of DDX3X is measured. Determine whether DDX3X shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and C1GALT1 expression is quantified. Does this perturbation result in a significant change in C1GALT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and C1GALT1 expression is quantified. Does this perturbation result in a significant change in C1GALT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
498,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor LDLR expression. Decide whether this perturbation leads to a significant alteration in LDLR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor LDLR expression. Decide whether this perturbation leads to a significant alteration in LDLR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of SPEN. Does this perturbation cause a significant change in SPEN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of SPEN. Does this perturbation cause a significant change in SPEN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4108,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor LINC00938 expression. Decide whether this perturbation leads to a significant alteration in LINC00938 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor LINC00938 expression. Decide whether this perturbation leads to a significant alteration in LINC00938 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of NSD1. Does perturbing STT3A lead to a significant change in NSD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of NSD1. Does perturbing STT3A lead to a significant change in NSD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in TGOLN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in TGOLN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1673,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and AC012594.1 expression is observed. Does this perturbation lead to a significant difference in AC012594.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and AC012594.1 expression is observed. Does this perturbation lead to a significant difference in AC012594.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of CTNNB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of CTNNB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and RGS20 expression is quantified. Does this perturbation result in a significant change in RGS20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and RGS20 expression is quantified. Does this perturbation result in a significant change in RGS20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of SETX. Does perturbing GBF1 lead to a significant change in SETX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of SETX. Does perturbing GBF1 lead to a significant change in SETX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and DOK3 expression is measured. Determine whether DOK3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and DOK3 expression is measured. Determine whether DOK3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in SPEN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in SPEN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of CCDC69 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of CCDC69 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3978,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor SEC23IP expression. Decide whether this perturbation leads to a significant alteration in SEC23IP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor SEC23IP expression. Decide whether this perturbation leads to a significant alteration in SEC23IP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of HMGCS1. Does this perturbation cause a significant change in HMGCS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of HMGCS1. Does this perturbation cause a significant change in HMGCS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in SERPING1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in SERPING1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of ACRV1. Does this perturbation cause a significant change in ACRV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of ACRV1. Does this perturbation cause a significant change in ACRV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2153,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and SNRNP25 expression is observed. Does this perturbation lead to a significant difference in SNRNP25 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and SNRNP25 expression is observed. Does this perturbation lead to a significant difference in SNRNP25 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4678,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor H1FX expression. Decide whether this perturbation leads to a significant alteration in H1FX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor H1FX expression. Decide whether this perturbation leads to a significant alteration in H1FX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of VIM-AS1 is measured. Determine whether VIM-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of VIM-AS1 is measured. Determine whether VIM-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4453,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and CENPC expression is observed. Does this perturbation lead to a significant difference in CENPC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and CENPC expression is observed. Does this perturbation lead to a significant difference in CENPC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of AP000688.8. Does this perturbation cause a significant change in AP000688.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of AP000688.8. Does this perturbation cause a significant change in AP000688.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of IL32 is measured. Determine whether IL32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of IL32 is measured. Determine whether IL32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2703,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RAI14 expression is observed. Does this perturbation lead to a significant difference in RAI14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RAI14 expression is observed. Does this perturbation lead to a significant difference in RAI14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
423,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and CD9 expression is observed. Does this perturbation lead to a significant difference in CD9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and CD9 expression is observed. Does this perturbation lead to a significant difference in CD9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of S100A10. Does perturbing CARS lead to a significant change in S100A10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of S100A10. Does perturbing CARS lead to a significant change in S100A10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of WDR72. Does this perturbation cause a significant change in WDR72 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of WDR72. Does this perturbation cause a significant change in WDR72 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and ZC3H7A expression is quantified. Does this perturbation result in a significant change in ZC3H7A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and ZC3H7A expression is quantified. Does this perturbation result in a significant change in ZC3H7A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1730,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of USP37 is measured. Does this perturbation cause a significant change in USP37 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of USP37 is measured. Does this perturbation cause a significant change in USP37 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and IL18R1 expression is measured. Determine whether IL18R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and IL18R1 expression is measured. Determine whether IL18R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of PTPN11 is measured. Determine whether PTPN11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of PTPN11 is measured. Determine whether PTPN11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and SERPINH1 expression is quantified. Does this perturbation result in a significant change in SERPINH1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and SERPINH1 expression is quantified. Does this perturbation result in a significant change in SERPINH1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of ZFHX3. Does perturbing SEC61A1 lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of ZFHX3. Does perturbing SEC61A1 lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and TSPAN33 expression is quantified. Does this perturbation result in a significant change in TSPAN33 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and TSPAN33 expression is quantified. Does this perturbation result in a significant change in TSPAN33 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4960,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of EIF4B is measured. Does this perturbation cause a significant change in EIF4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of EIF4B is measured. Does this perturbation cause a significant change in EIF4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of HOTAIRM1 is measured. Determine whether HOTAIRM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of HOTAIRM1 is measured. Determine whether HOTAIRM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of HP1BP3. Does perturbing HARS lead to a significant change in HP1BP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of HP1BP3. Does perturbing HARS lead to a significant change in HP1BP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4923,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and YTHDF2 expression is observed. Does this perturbation lead to a significant difference in YTHDF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and YTHDF2 expression is observed. Does this perturbation lead to a significant difference in YTHDF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of ROCK1. Does this perturbation cause a significant change in ROCK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of ROCK1. Does this perturbation cause a significant change in ROCK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and NPDC1 expression is quantified. Does this perturbation result in a significant change in NPDC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and NPDC1 expression is quantified. Does this perturbation result in a significant change in NPDC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and RP11-435O5.4 expression is quantified. Does this perturbation result in a significant change in RP11-435O5.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and RP11-435O5.4 expression is quantified. Does this perturbation result in a significant change in RP11-435O5.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1788,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor KCNH7 expression. Decide whether this perturbation leads to a significant alteration in KCNH7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor KCNH7 expression. Decide whether this perturbation leads to a significant alteration in KCNH7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and ZNF292 expression is quantified. Does this perturbation result in a significant change in ZNF292 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and ZNF292 expression is quantified. Does this perturbation result in a significant change in ZNF292 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of HIST1H2BC is measured. Determine whether HIST1H2BC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of HIST1H2BC is measured. Determine whether HIST1H2BC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of SERPINH1. Does this perturbation cause a significant change in SERPINH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of SERPINH1. Does this perturbation cause a significant change in SERPINH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3793,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and POLR2J3 expression is observed. Does this perturbation lead to a significant difference in POLR2J3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and POLR2J3 expression is observed. Does this perturbation lead to a significant difference in POLR2J3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in RP11-2H8.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in RP11-2H8.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of LTB is measured. Determine whether LTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of LTB is measured. Determine whether LTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1633,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and DNASE2 expression is observed. Does this perturbation lead to a significant difference in DNASE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and DNASE2 expression is observed. Does this perturbation lead to a significant difference in DNASE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of GPRC5C. Does perturbing NEDD8 lead to a significant change in GPRC5C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of GPRC5C. Does perturbing NEDD8 lead to a significant change in GPRC5C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and AP000688.8 expression is quantified. Does this perturbation result in a significant change in AP000688.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and AP000688.8 expression is quantified. Does this perturbation result in a significant change in AP000688.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of SOBP. Does perturbing EIF2S1 lead to a significant change in SOBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of SOBP. Does perturbing EIF2S1 lead to a significant change in SOBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of SNHG10 is measured. Determine whether SNHG10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of SNHG10 is measured. Determine whether SNHG10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
92,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RP11-141B14.1 expression is quantified. Does this perturbation result in a significant change in RP11-141B14.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RP11-141B14.1 expression is quantified. Does this perturbation result in a significant change in RP11-141B14.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1873,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and AC096559.1 expression is observed. Does this perturbation lead to a significant difference in AC096559.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and AC096559.1 expression is observed. Does this perturbation lead to a significant difference in AC096559.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of HP1BP3 is measured. Determine whether HP1BP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of HP1BP3 is measured. Determine whether HP1BP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of WDR72 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of WDR72 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3273,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and TSC22D4 expression is observed. Does this perturbation lead to a significant difference in TSC22D4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and TSC22D4 expression is observed. Does this perturbation lead to a significant difference in TSC22D4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2688,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor KCTD19 expression. Decide whether this perturbation leads to a significant alteration in KCTD19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor KCTD19 expression. Decide whether this perturbation leads to a significant alteration in KCTD19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1120,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of RP11-640M9.1 is measured. Does this perturbation cause a significant change in RP11-640M9.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of RP11-640M9.1 is measured. Does this perturbation cause a significant change in RP11-640M9.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in RP11-16E12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in RP11-16E12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of ATP2A3. Does this perturbation cause a significant change in ATP2A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of ATP2A3. Does this perturbation cause a significant change in ATP2A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of CCRL2 is measured. Determine whether CCRL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of CCRL2 is measured. Determine whether CCRL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and ANKRD10 expression is measured. Determine whether ANKRD10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and ANKRD10 expression is measured. Determine whether ANKRD10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and RP11-363D14.1 expression is measured. Determine whether RP11-363D14.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and RP11-363D14.1 expression is measured. Determine whether RP11-363D14.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in LRIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in LRIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of VAMP2 is measured. Determine whether VAMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of VAMP2 is measured. Determine whether VAMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of RP11-471M2.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of RP11-471M2.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of PGM3. Does perturbing TTI2 lead to a significant change in PGM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of PGM3. Does perturbing TTI2 lead to a significant change in PGM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of GOT1 is measured. Determine whether GOT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of GOT1 is measured. Determine whether GOT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3448,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor CCDC69 expression. Decide whether this perturbation leads to a significant alteration in CCDC69 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor CCDC69 expression. Decide whether this perturbation leads to a significant alteration in CCDC69 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of ZNF280B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of ZNF280B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
540,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of PCF11 is measured. Does this perturbation cause a significant change in PCF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of PCF11 is measured. Does this perturbation cause a significant change in PCF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of LRIF1. Does this perturbation cause a significant change in LRIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of LRIF1. Does this perturbation cause a significant change in LRIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2360,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of FYTTD1 is measured. Does this perturbation cause a significant change in FYTTD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of FYTTD1 is measured. Does this perturbation cause a significant change in FYTTD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of CENPC is measured. Determine whether CENPC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of CENPC is measured. Determine whether CENPC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in RGS20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in RGS20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
983,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and TOB2 expression is observed. Does this perturbation lead to a significant difference in TOB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and TOB2 expression is observed. Does this perturbation lead to a significant difference in TOB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2123,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in KCNH7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in KCNH7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of TGOLN2 is measured. Determine whether TGOLN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of TGOLN2 is measured. Determine whether TGOLN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1503,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and ZNF292 expression is observed. Does this perturbation lead to a significant difference in ZNF292 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and ZNF292 expression is observed. Does this perturbation lead to a significant difference in ZNF292 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4998,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor ZCCHC11 expression. Decide whether this perturbation leads to a significant alteration in ZCCHC11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor ZCCHC11 expression. Decide whether this perturbation leads to a significant alteration in ZCCHC11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
203,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and KLK1 expression is observed. Does this perturbation lead to a significant difference in KLK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and KLK1 expression is observed. Does this perturbation lead to a significant difference in KLK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of CHST12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of CHST12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and SETX expression is quantified. Does this perturbation result in a significant change in SETX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and SETX expression is quantified. Does this perturbation result in a significant change in SETX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of SPCS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of SPCS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ZFP36L2 expression is quantified. Does this perturbation result in a significant change in ZFP36L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ZFP36L2 expression is quantified. Does this perturbation result in a significant change in ZFP36L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and POLR2J3 expression is measured. Determine whether POLR2J3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and POLR2J3 expression is measured. Determine whether POLR2J3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of MTPN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of MTPN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in RP11-138C9.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in RP11-138C9.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1663,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and RP11-247A12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-247A12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and RP11-247A12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-247A12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in CRNDE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in CRNDE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of RP11-666A20.4 is measured. Determine whether RP11-666A20.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of RP11-666A20.4 is measured. Determine whether RP11-666A20.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in TMOD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in TMOD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and EBI3 expression is measured. Determine whether EBI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and EBI3 expression is measured. Determine whether EBI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in MARCH8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in MARCH8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and RGS3 expression is measured. Determine whether RGS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and RGS3 expression is measured. Determine whether RGS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and S100A11 expression is measured. Determine whether S100A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and S100A11 expression is measured. Determine whether S100A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in NOX5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in NOX5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of HIST1H3D. Does perturbing DARS lead to a significant change in HIST1H3D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of HIST1H3D. Does perturbing DARS lead to a significant change in HIST1H3D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2300,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of DDIT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of DDIT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in UHRF1BP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in UHRF1BP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of RPL39. Does this perturbation cause a significant change in RPL39 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of RPL39. Does this perturbation cause a significant change in RPL39 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1620,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of ATP6AP2 is measured. Does this perturbation cause a significant change in ATP6AP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of ATP6AP2 is measured. Does this perturbation cause a significant change in ATP6AP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in BIRC5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in BIRC5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in TMEM60 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in TMEM60 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and FAM212A expression is measured. Determine whether FAM212A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and FAM212A expression is measured. Determine whether FAM212A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of UHRF1BP1L. Does this perturbation cause a significant change in UHRF1BP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of UHRF1BP1L. Does this perturbation cause a significant change in UHRF1BP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of RP11-573D15.2. Does perturbing DDOST lead to a significant change in RP11-573D15.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of RP11-573D15.2. Does perturbing DDOST lead to a significant change in RP11-573D15.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of GUSB. Does this perturbation cause a significant change in GUSB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of GUSB. Does this perturbation cause a significant change in GUSB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of SPEN. Does perturbing UFM1 lead to a significant change in SPEN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of SPEN. Does perturbing UFM1 lead to a significant change in SPEN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of BRWD3. Does perturbing DAD1 lead to a significant change in BRWD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of BRWD3. Does perturbing DAD1 lead to a significant change in BRWD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and SNHG10 expression is measured. Determine whether SNHG10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and SNHG10 expression is measured. Determine whether SNHG10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1723,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and VIM-AS1 expression is observed. Does this perturbation lead to a significant difference in VIM-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and VIM-AS1 expression is observed. Does this perturbation lead to a significant difference in VIM-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of USP37 is measured. Determine whether USP37 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of USP37 is measured. Determine whether USP37 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of TLK2. Does perturbing GNPNAT1 lead to a significant change in TLK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of TLK2. Does perturbing GNPNAT1 lead to a significant change in TLK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and RGS20 expression is measured. Determine whether RGS20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and RGS20 expression is measured. Determine whether RGS20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of GUSB is measured. Determine whether GUSB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of GUSB is measured. Determine whether GUSB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4840,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of EPS15 is measured. Does this perturbation cause a significant change in EPS15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of EPS15 is measured. Does this perturbation cause a significant change in EPS15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of PSORS1C1 is measured. Determine whether PSORS1C1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of PSORS1C1 is measured. Determine whether PSORS1C1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PHF19 expression is quantified. Does this perturbation result in a significant change in PHF19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PHF19 expression is quantified. Does this perturbation result in a significant change in PHF19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and ACRV1 expression is quantified. Does this perturbation result in a significant change in ACRV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and ACRV1 expression is quantified. Does this perturbation result in a significant change in ACRV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1998,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor TLK2 expression. Decide whether this perturbation leads to a significant alteration in TLK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor TLK2 expression. Decide whether this perturbation leads to a significant alteration in TLK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of CYP17A1-AS1 is measured. Determine whether CYP17A1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of CYP17A1-AS1 is measured. Determine whether CYP17A1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1748,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor RPL39 expression. Decide whether this perturbation leads to a significant alteration in RPL39 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor RPL39 expression. Decide whether this perturbation leads to a significant alteration in RPL39 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of S100A11 is measured. Determine whether S100A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of S100A11 is measured. Determine whether S100A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and LRIF1 expression is quantified. Does this perturbation result in a significant change in LRIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and LRIF1 expression is quantified. Does this perturbation result in a significant change in LRIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
848,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and TKTL1 expression is measured. Determine whether TKTL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and TKTL1 expression is measured. Determine whether TKTL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of PLA2G15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of PLA2G15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and FOXO6 expression is measured. Determine whether FOXO6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and FOXO6 expression is measured. Determine whether FOXO6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of C17orf64. Does perturbing TIMM44 lead to a significant change in C17orf64 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of C17orf64. Does perturbing TIMM44 lead to a significant change in C17orf64 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
580,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of MYH7B is measured. Does this perturbation cause a significant change in MYH7B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of MYH7B is measured. Does this perturbation cause a significant change in MYH7B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and IDS expression is measured. Determine whether IDS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and IDS expression is measured. Determine whether IDS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2470,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of SETX is measured. Does this perturbation cause a significant change in SETX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of SETX is measured. Does this perturbation cause a significant change in SETX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of GRN is measured. Determine whether GRN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of GRN is measured. Determine whether GRN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of SLC26A1 is measured. Determine whether SLC26A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of SLC26A1 is measured. Determine whether SLC26A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of KCNE3 is measured. Determine whether KCNE3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of KCNE3 is measured. Determine whether KCNE3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
263,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and DOK3 expression is observed. Does this perturbation lead to a significant difference in DOK3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and DOK3 expression is observed. Does this perturbation lead to a significant difference in DOK3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3443,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and CCDC69 expression is observed. Does this perturbation lead to a significant difference in CCDC69 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and CCDC69 expression is observed. Does this perturbation lead to a significant difference in CCDC69 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4073,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and RP1-274L7.1 expression is observed. Does this perturbation lead to a significant difference in RP1-274L7.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and RP1-274L7.1 expression is observed. Does this perturbation lead to a significant difference in RP1-274L7.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of NCKAP1L. Does this perturbation cause a significant change in NCKAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of NCKAP1L. Does this perturbation cause a significant change in NCKAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of TIPARP. Does perturbing EIF2S1 lead to a significant change in TIPARP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of TIPARP. Does perturbing EIF2S1 lead to a significant change in TIPARP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of CTCFL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of CTCFL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of HRK is measured. Determine whether HRK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of HRK is measured. Determine whether HRK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in JUND expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in JUND expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and PCK2 expression is measured. Determine whether PCK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and PCK2 expression is measured. Determine whether PCK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of CMTM6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of CMTM6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2168,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor PDK2 expression. Decide whether this perturbation leads to a significant alteration in PDK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor PDK2 expression. Decide whether this perturbation leads to a significant alteration in PDK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of QSER1. Does perturbing EIF2B2 lead to a significant change in QSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of QSER1. Does perturbing EIF2B2 lead to a significant change in QSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
333,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and PCK2 expression is observed. Does this perturbation lead to a significant difference in PCK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and PCK2 expression is observed. Does this perturbation lead to a significant difference in PCK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of S100A10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of S100A10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and PTBP3 expression is quantified. Does this perturbation result in a significant change in PTBP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and PTBP3 expression is quantified. Does this perturbation result in a significant change in PTBP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2753,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RP11-685N10.1 expression is observed. Does this perturbation lead to a significant difference in RP11-685N10.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RP11-685N10.1 expression is observed. Does this perturbation lead to a significant difference in RP11-685N10.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of DOCK8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of DOCK8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of PIK3R3. Does perturbing CCND3 lead to a significant change in PIK3R3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of PIK3R3. Does perturbing CCND3 lead to a significant change in PIK3R3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PSMD14. Does this perturbation cause a significant change in PSMD14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PSMD14. Does this perturbation cause a significant change in PSMD14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1653,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and EBI3 expression is observed. Does this perturbation lead to a significant difference in EBI3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and EBI3 expression is observed. Does this perturbation lead to a significant difference in EBI3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of SKIL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of SKIL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of EPS15. Does this perturbation cause a significant change in EPS15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of EPS15. Does this perturbation cause a significant change in EPS15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of SETX is measured. Determine whether SETX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of SETX is measured. Determine whether SETX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1910,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of CTD-2587M2.1 is measured. Does this perturbation cause a significant change in CTD-2587M2.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of CTD-2587M2.1 is measured. Does this perturbation cause a significant change in CTD-2587M2.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4548,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor CLDN11 expression. Decide whether this perturbation leads to a significant alteration in CLDN11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor CLDN11 expression. Decide whether this perturbation leads to a significant alteration in CLDN11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
463,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and ERV3-1 expression is observed. Does this perturbation lead to a significant difference in ERV3-1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and ERV3-1 expression is observed. Does this perturbation lead to a significant difference in ERV3-1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
108,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor NBEAL2 expression. Decide whether this perturbation leads to a significant alteration in NBEAL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor NBEAL2 expression. Decide whether this perturbation leads to a significant alteration in NBEAL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of ZNF341. Does perturbing PTDSS1 lead to a significant change in ZNF341 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of ZNF341. Does perturbing PTDSS1 lead to a significant change in ZNF341 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
29,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RAI14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RAI14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and TLN1 expression is quantified. Does this perturbation result in a significant change in TLN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and TLN1 expression is quantified. Does this perturbation result in a significant change in TLN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of RNF19A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of RNF19A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of S100A11. Does this perturbation cause a significant change in S100A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of S100A11. Does this perturbation cause a significant change in S100A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of RP11-435O5.4. Does this perturbation cause a significant change in RP11-435O5.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of RP11-435O5.4. Does this perturbation cause a significant change in RP11-435O5.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in RP11-863K10.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in RP11-863K10.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of PBDC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of PBDC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in PIK3R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in PIK3R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of STARD9. Does perturbing COPZ1 lead to a significant change in STARD9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of STARD9. Does perturbing COPZ1 lead to a significant change in STARD9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and WARS expression is measured. Determine whether WARS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and WARS expression is measured. Determine whether WARS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of PKDCC. Does this perturbation cause a significant change in PKDCC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of PKDCC. Does this perturbation cause a significant change in PKDCC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and ZMYND8 expression is quantified. Does this perturbation result in a significant change in ZMYND8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and ZMYND8 expression is quantified. Does this perturbation result in a significant change in ZMYND8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2053,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and EP300 expression is observed. Does this perturbation lead to a significant difference in EP300 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and EP300 expression is observed. Does this perturbation lead to a significant difference in EP300 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of RP11-430H10.1. Does this perturbation cause a significant change in RP11-430H10.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of RP11-430H10.1. Does this perturbation cause a significant change in RP11-430H10.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3840,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of TRPM4 is measured. Does this perturbation cause a significant change in TRPM4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of TRPM4 is measured. Does this perturbation cause a significant change in TRPM4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2883,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and RP11-499F3.2 expression is observed. Does this perturbation lead to a significant difference in RP11-499F3.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and RP11-499F3.2 expression is observed. Does this perturbation lead to a significant difference in RP11-499F3.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of IL8. Does perturbing DDRGK1 lead to a significant change in IL8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of IL8. Does perturbing DDRGK1 lead to a significant change in IL8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and ACE expression is measured. Determine whether ACE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and ACE expression is measured. Determine whether ACE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in UBE2V1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in UBE2V1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and MANF expression is measured. Determine whether MANF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and MANF expression is measured. Determine whether MANF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and HM13 expression is quantified. Does this perturbation result in a significant change in HM13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and HM13 expression is quantified. Does this perturbation result in a significant change in HM13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3813,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and RP11-445H22.3 expression is observed. Does this perturbation lead to a significant difference in RP11-445H22.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and RP11-445H22.3 expression is observed. Does this perturbation lead to a significant difference in RP11-445H22.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5050,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of CFH is measured. Does this perturbation cause a significant change in CFH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of CFH is measured. Does this perturbation cause a significant change in CFH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3440,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of CCDC69 is measured. Does this perturbation cause a significant change in CCDC69 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of CCDC69 is measured. Does this perturbation cause a significant change in CCDC69 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of MARCH8. Does this perturbation cause a significant change in MARCH8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of MARCH8. Does this perturbation cause a significant change in MARCH8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of IDS. Does this perturbation cause a significant change in IDS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of IDS. Does this perturbation cause a significant change in IDS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of RAD51AP1 is measured. Determine whether RAD51AP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of RAD51AP1 is measured. Determine whether RAD51AP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5148,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor RAD51AP1 expression. Decide whether this perturbation leads to a significant alteration in RAD51AP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor RAD51AP1 expression. Decide whether this perturbation leads to a significant alteration in RAD51AP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
710,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of FAM114A1 is measured. Does this perturbation cause a significant change in FAM114A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of FAM114A1 is measured. Does this perturbation cause a significant change in FAM114A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2953,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and ATP5EP2 expression is observed. Does this perturbation lead to a significant difference in ATP5EP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and ATP5EP2 expression is observed. Does this perturbation lead to a significant difference in ATP5EP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of RP11-304M2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of RP11-304M2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
6,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of ZNF429 is measured. Determine whether ZNF429 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of ZNF429 is measured. Determine whether ZNF429 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and CPQ expression is quantified. Does this perturbation result in a significant change in CPQ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and CPQ expression is quantified. Does this perturbation result in a significant change in CPQ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in MT2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in MT2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
433,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and CLINT1 expression is observed. Does this perturbation lead to a significant difference in CLINT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and CLINT1 expression is observed. Does this perturbation lead to a significant difference in CLINT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and UBE2V1 expression is measured. Determine whether UBE2V1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and UBE2V1 expression is measured. Determine whether UBE2V1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2373,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and PPP4R2 expression is observed. Does this perturbation lead to a significant difference in PPP4R2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and PPP4R2 expression is observed. Does this perturbation lead to a significant difference in PPP4R2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in SAMM50 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in SAMM50 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and HIST1H2AM expression is measured. Determine whether HIST1H2AM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and HIST1H2AM expression is measured. Determine whether HIST1H2AM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3863,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and TNFRSF10B expression is observed. Does this perturbation lead to a significant difference in TNFRSF10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and TNFRSF10B expression is observed. Does this perturbation lead to a significant difference in TNFRSF10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and TSC22D4 expression is quantified. Does this perturbation result in a significant change in TSC22D4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and TSC22D4 expression is quantified. Does this perturbation result in a significant change in TSC22D4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ZXDA. Does this perturbation cause a significant change in ZXDA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ZXDA. Does this perturbation cause a significant change in ZXDA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of RP11-95O2.5 is measured. Determine whether RP11-95O2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of RP11-95O2.5 is measured. Determine whether RP11-95O2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of ADAMTS10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of ADAMTS10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2350,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of IL13RA1 is measured. Does this perturbation cause a significant change in IL13RA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of IL13RA1 is measured. Does this perturbation cause a significant change in IL13RA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of LIMS1. Does this perturbation cause a significant change in LIMS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of LIMS1. Does this perturbation cause a significant change in LIMS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in DDIT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in DDIT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and PCF11 expression is measured. Determine whether PCF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and PCF11 expression is measured. Determine whether PCF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of TTC32 is measured. Determine whether TTC32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of TTC32 is measured. Determine whether TTC32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4288,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of NFAT5. Does perturbing GMPPB lead to a significant change in NFAT5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of NFAT5. Does perturbing GMPPB lead to a significant change in NFAT5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of CLINT1. Does this perturbation cause a significant change in CLINT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of CLINT1. Does this perturbation cause a significant change in CLINT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
440,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of NCKAP1L is measured. Does this perturbation cause a significant change in NCKAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of NCKAP1L is measured. Does this perturbation cause a significant change in NCKAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of TKTL1. Does this perturbation cause a significant change in TKTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of TKTL1. Does this perturbation cause a significant change in TKTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
350,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of IL18R1 is measured. Does this perturbation cause a significant change in IL18R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of IL18R1 is measured. Does this perturbation cause a significant change in IL18R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of SDF4. Does this perturbation cause a significant change in SDF4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of SDF4. Does this perturbation cause a significant change in SDF4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of ZNF292. Does this perturbation cause a significant change in ZNF292 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of ZNF292. Does this perturbation cause a significant change in ZNF292 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of STK17B. Does perturbing XRN1 lead to a significant change in STK17B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of STK17B. Does perturbing XRN1 lead to a significant change in STK17B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
890,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of APOL4 is measured. Does this perturbation cause a significant change in APOL4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of APOL4 is measured. Does this perturbation cause a significant change in APOL4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and SPEN expression is measured. Determine whether SPEN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and SPEN expression is measured. Determine whether SPEN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in POLR2J3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in POLR2J3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3298,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor GS1-166A23.1 expression. Decide whether this perturbation leads to a significant alteration in GS1-166A23.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor GS1-166A23.1 expression. Decide whether this perturbation leads to a significant alteration in GS1-166A23.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3938,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ZXDA expression. Decide whether this perturbation leads to a significant alteration in ZXDA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ZXDA expression. Decide whether this perturbation leads to a significant alteration in ZXDA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in CHD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in CHD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2258,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor AC015987.1 expression. Decide whether this perturbation leads to a significant alteration in AC015987.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor AC015987.1 expression. Decide whether this perturbation leads to a significant alteration in AC015987.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2088,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor PGM3 expression. Decide whether this perturbation leads to a significant alteration in PGM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor PGM3 expression. Decide whether this perturbation leads to a significant alteration in PGM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and HIST1H2BC expression is measured. Determine whether HIST1H2BC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and HIST1H2BC expression is measured. Determine whether HIST1H2BC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
838,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor RP11-138C9.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-138C9.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor RP11-138C9.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-138C9.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of RP3-465N24.6. Does perturbing SRP68 lead to a significant change in RP3-465N24.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of RP3-465N24.6. Does perturbing SRP68 lead to a significant change in RP3-465N24.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and HMGCS1 expression is quantified. Does this perturbation result in a significant change in HMGCS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and HMGCS1 expression is quantified. Does this perturbation result in a significant change in HMGCS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and PGM3 expression is measured. Determine whether PGM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and PGM3 expression is measured. Determine whether PGM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3800,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of TOPBP1 is measured. Does this perturbation cause a significant change in TOPBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of TOPBP1 is measured. Does this perturbation cause a significant change in TOPBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of UBE3A is measured. Determine whether UBE3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of UBE3A is measured. Determine whether UBE3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and NFAT5 expression is quantified. Does this perturbation result in a significant change in NFAT5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and NFAT5 expression is quantified. Does this perturbation result in a significant change in NFAT5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in TFPI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in TFPI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of PGM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of PGM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3463,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and CHST12 expression is observed. Does this perturbation lead to a significant difference in CHST12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and CHST12 expression is observed. Does this perturbation lead to a significant difference in CHST12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and SLBP expression is quantified. Does this perturbation result in a significant change in SLBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and SLBP expression is quantified. Does this perturbation result in a significant change in SLBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of ARHGAP6. Does this perturbation cause a significant change in ARHGAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of ARHGAP6. Does this perturbation cause a significant change in ARHGAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and SRP72 expression is measured. Determine whether SRP72 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and SRP72 expression is measured. Determine whether SRP72 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and TOPBP1 expression is measured. Determine whether TOPBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and TOPBP1 expression is measured. Determine whether TOPBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of VIMP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of VIMP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of IRF7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of IRF7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2468,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor NUFIP2 expression. Decide whether this perturbation leads to a significant alteration in NUFIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor NUFIP2 expression. Decide whether this perturbation leads to a significant alteration in NUFIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2408,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor P4HA2 expression. Decide whether this perturbation leads to a significant alteration in P4HA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor P4HA2 expression. Decide whether this perturbation leads to a significant alteration in P4HA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and HIST1H1D expression is measured. Determine whether HIST1H1D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and HIST1H1D expression is measured. Determine whether HIST1H1D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and USP37 expression is quantified. Does this perturbation result in a significant change in USP37 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and USP37 expression is quantified. Does this perturbation result in a significant change in USP37 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of CDCA3. Does perturbing UFM1 lead to a significant change in CDCA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of CDCA3. Does perturbing UFM1 lead to a significant change in CDCA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of AFF1. Does perturbing TARS lead to a significant change in AFF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of AFF1. Does perturbing TARS lead to a significant change in AFF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
19,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and P4HA2 expression is measured. Determine whether P4HA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and P4HA2 expression is measured. Determine whether P4HA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4498,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor SMCO1 expression. Decide whether this perturbation leads to a significant alteration in SMCO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor SMCO1 expression. Decide whether this perturbation leads to a significant alteration in SMCO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of NFE2L3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of NFE2L3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of NFE2. Does perturbing DDIT3 lead to a significant change in NFE2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of NFE2. Does perturbing DDIT3 lead to a significant change in NFE2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4980,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of UHMK1 is measured. Does this perturbation cause a significant change in UHMK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of UHMK1 is measured. Does this perturbation cause a significant change in UHMK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of ANKRD10. Does this perturbation cause a significant change in ANKRD10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of ANKRD10. Does this perturbation cause a significant change in ANKRD10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in DOK3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in DOK3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in MORF4L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in MORF4L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of LINC00938. Does perturbing UFM1 lead to a significant change in LINC00938 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of LINC00938. Does perturbing UFM1 lead to a significant change in LINC00938 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4578,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2140,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of NINJ2 is measured. Does this perturbation cause a significant change in NINJ2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of NINJ2 is measured. Does this perturbation cause a significant change in NINJ2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1468,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor RSAD2 expression. Decide whether this perturbation leads to a significant alteration in RSAD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor RSAD2 expression. Decide whether this perturbation leads to a significant alteration in RSAD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and HPCAL1 expression is measured. Determine whether HPCAL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and HPCAL1 expression is measured. Determine whether HPCAL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and RP11-227G15.8 expression is quantified. Does this perturbation result in a significant change in RP11-227G15.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and RP11-227G15.8 expression is quantified. Does this perturbation result in a significant change in RP11-227G15.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of ANKRD33. Does this perturbation cause a significant change in ANKRD33 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of ANKRD33. Does this perturbation cause a significant change in ANKRD33 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2943,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and SKIL expression is observed. Does this perturbation lead to a significant difference in SKIL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and SKIL expression is observed. Does this perturbation lead to a significant difference in SKIL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
410,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of SPINK5 is measured. Does this perturbation cause a significant change in SPINK5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of SPINK5 is measured. Does this perturbation cause a significant change in SPINK5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and RGS20 expression is measured. Determine whether RGS20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and RGS20 expression is measured. Determine whether RGS20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of RP11-95O2.5. Does perturbing PPWD1 lead to a significant change in RP11-95O2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of RP11-95O2.5. Does perturbing PPWD1 lead to a significant change in RP11-95O2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
743,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and ANXA4 expression is observed. Does this perturbation lead to a significant difference in ANXA4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and ANXA4 expression is observed. Does this perturbation lead to a significant difference in ANXA4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and NFE2L3 expression is measured. Determine whether NFE2L3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and NFE2L3 expression is measured. Determine whether NFE2L3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1823,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and DDIT4 expression is observed. Does this perturbation lead to a significant difference in DDIT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and DDIT4 expression is observed. Does this perturbation lead to a significant difference in DDIT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5138,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor CTC-308K20.1 expression. Decide whether this perturbation leads to a significant alteration in CTC-308K20.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor CTC-308K20.1 expression. Decide whether this perturbation leads to a significant alteration in CTC-308K20.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of PLB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of PLB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
59,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and C6orf48 expression is measured. Determine whether C6orf48 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and C6orf48 expression is measured. Determine whether C6orf48 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in APOBEC3D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in APOBEC3D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of UFD1L. Does perturbing GBF1 lead to a significant change in UFD1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of UFD1L. Does perturbing GBF1 lead to a significant change in UFD1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3093,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and GNPTG expression is observed. Does this perturbation lead to a significant difference in GNPTG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and GNPTG expression is observed. Does this perturbation lead to a significant difference in GNPTG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and NOSTRIN expression is measured. Determine whether NOSTRIN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and NOSTRIN expression is measured. Determine whether NOSTRIN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of AC007038.7. Does this perturbation cause a significant change in AC007038.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of AC007038.7. Does this perturbation cause a significant change in AC007038.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and KIAA0922 expression is quantified. Does this perturbation result in a significant change in KIAA0922 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and KIAA0922 expression is quantified. Does this perturbation result in a significant change in KIAA0922 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and RP11-434H6.6 expression is measured. Determine whether RP11-434H6.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and RP11-434H6.6 expression is measured. Determine whether RP11-434H6.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1420,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of RP11-61E11.1 is measured. Does this perturbation cause a significant change in RP11-61E11.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of RP11-61E11.1 is measured. Does this perturbation cause a significant change in RP11-61E11.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and TNFRSF10B expression is quantified. Does this perturbation result in a significant change in TNFRSF10B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and TNFRSF10B expression is quantified. Does this perturbation result in a significant change in TNFRSF10B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2518,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor RBM12B-AS1 expression. Decide whether this perturbation leads to a significant alteration in RBM12B-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor RBM12B-AS1 expression. Decide whether this perturbation leads to a significant alteration in RBM12B-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2023,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and ABI2 expression is observed. Does this perturbation lead to a significant difference in ABI2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and ABI2 expression is observed. Does this perturbation lead to a significant difference in ABI2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and PPM1N expression is quantified. Does this perturbation result in a significant change in PPM1N expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and PPM1N expression is quantified. Does this perturbation result in a significant change in PPM1N expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of HLTF is measured. Determine whether HLTF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of HLTF is measured. Determine whether HLTF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in NCKAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in NCKAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and RP11-789C1.1 expression is quantified. Does this perturbation result in a significant change in RP11-789C1.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and RP11-789C1.1 expression is quantified. Does this perturbation result in a significant change in RP11-789C1.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
120,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of NRIP1 is measured. Does this perturbation cause a significant change in NRIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of NRIP1 is measured. Does this perturbation cause a significant change in NRIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of CELF6. Does perturbing P4HB lead to a significant change in CELF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of CELF6. Does perturbing P4HB lead to a significant change in CELF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and SETX expression is measured. Determine whether SETX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and SETX expression is measured. Determine whether SETX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of PRRC2B. Does this perturbation cause a significant change in PRRC2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of PRRC2B. Does this perturbation cause a significant change in PRRC2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in CTSV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in CTSV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of PDK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of PDK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
20,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RP11-685N10.1 is measured. Determine whether RP11-685N10.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RP11-685N10.1 is measured. Determine whether RP11-685N10.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and SLC25A35 expression is quantified. Does this perturbation result in a significant change in SLC25A35 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and SLC25A35 expression is quantified. Does this perturbation result in a significant change in SLC25A35 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and RIMS3 expression is quantified. Does this perturbation result in a significant change in RIMS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and RIMS3 expression is quantified. Does this perturbation result in a significant change in RIMS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of ZCCHC11 is measured. Determine whether ZCCHC11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of ZCCHC11 is measured. Determine whether ZCCHC11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of RP11-132A1.4. Does perturbing DAD1 lead to a significant change in RP11-132A1.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of RP11-132A1.4. Does perturbing DAD1 lead to a significant change in RP11-132A1.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and RAD51AP1 expression is measured. Determine whether RAD51AP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and RAD51AP1 expression is measured. Determine whether RAD51AP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3723,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and ARHGAP11A expression is observed. Does this perturbation lead to a significant difference in ARHGAP11A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and ARHGAP11A expression is observed. Does this perturbation lead to a significant difference in ARHGAP11A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and KIAA0922 expression is measured. Determine whether KIAA0922 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and KIAA0922 expression is measured. Determine whether KIAA0922 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of KCNJ13. Does this perturbation cause a significant change in KCNJ13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of KCNJ13. Does this perturbation cause a significant change in KCNJ13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in LRRC4B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in LRRC4B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and ZP3 expression is measured. Determine whether ZP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and ZP3 expression is measured. Determine whether ZP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of EIF4B is measured. Determine whether EIF4B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of EIF4B is measured. Determine whether EIF4B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of PPP1R16B. Does perturbing PPWD1 lead to a significant change in PPP1R16B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of PPP1R16B. Does perturbing PPWD1 lead to a significant change in PPP1R16B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1000,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of RP11-334C17.5 is measured. Does this perturbation cause a significant change in RP11-334C17.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of RP11-334C17.5 is measured. Does this perturbation cause a significant change in RP11-334C17.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of GUSB. Does perturbing SAMM50 lead to a significant change in GUSB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of GUSB. Does perturbing SAMM50 lead to a significant change in GUSB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of MORC2-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of MORC2-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2138,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor SLBP expression. Decide whether this perturbation leads to a significant alteration in SLBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor SLBP expression. Decide whether this perturbation leads to a significant alteration in SLBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in PIK3R3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in PIK3R3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4880,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of WARS is measured. Does this perturbation cause a significant change in WARS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of WARS is measured. Does this perturbation cause a significant change in WARS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3603,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and IL2RB expression is observed. Does this perturbation lead to a significant difference in IL2RB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and IL2RB expression is observed. Does this perturbation lead to a significant difference in IL2RB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3593,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and RP11-2H8.2 expression is observed. Does this perturbation lead to a significant difference in RP11-2H8.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and RP11-2H8.2 expression is observed. Does this perturbation lead to a significant difference in RP11-2H8.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
708,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor UQCRB expression. Decide whether this perturbation leads to a significant alteration in UQCRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor UQCRB expression. Decide whether this perturbation leads to a significant alteration in UQCRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and RSAD2 expression is measured. Determine whether RSAD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and RSAD2 expression is measured. Determine whether RSAD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in EP300 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in EP300 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in PHF21A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in PHF21A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5143,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and RAD51AP1 expression is observed. Does this perturbation lead to a significant difference in RAD51AP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and RAD51AP1 expression is observed. Does this perturbation lead to a significant difference in RAD51AP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of LTB is measured. Determine whether LTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of LTB is measured. Determine whether LTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of RILPL2. Does perturbing HSD17B12 lead to a significant change in RILPL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of RILPL2. Does perturbing HSD17B12 lead to a significant change in RILPL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of CTD-2001C12.1 is measured. Determine whether CTD-2001C12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of CTD-2001C12.1 is measured. Determine whether CTD-2001C12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of SETX. Does perturbing SRP72 lead to a significant change in SETX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of SETX. Does perturbing SRP72 lead to a significant change in SETX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
80,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of PHF3 is measured. Does this perturbation cause a significant change in PHF3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of PHF3 is measured. Does this perturbation cause a significant change in PHF3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
950,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of HERC2 is measured. Does this perturbation cause a significant change in HERC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of HERC2 is measured. Does this perturbation cause a significant change in HERC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of PIK3R1. Does perturbing SPCS2 lead to a significant change in PIK3R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of PIK3R1. Does perturbing SPCS2 lead to a significant change in PIK3R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4188,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor ANKRD33 expression. Decide whether this perturbation leads to a significant alteration in ANKRD33 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor ANKRD33 expression. Decide whether this perturbation leads to a significant alteration in ANKRD33 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5103,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and PIK3R1 expression is observed. Does this perturbation lead to a significant difference in PIK3R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and PIK3R1 expression is observed. Does this perturbation lead to a significant difference in PIK3R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and PKDCC expression is quantified. Does this perturbation result in a significant change in PKDCC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and PKDCC expression is quantified. Does this perturbation result in a significant change in PKDCC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and GPR146 expression is quantified. Does this perturbation result in a significant change in GPR146 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and GPR146 expression is quantified. Does this perturbation result in a significant change in GPR146 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of LINC00862 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of LINC00862 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of KANSL1L is measured. Determine whether KANSL1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of KANSL1L is measured. Determine whether KANSL1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ZP3 expression is quantified. Does this perturbation result in a significant change in ZP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ZP3 expression is quantified. Does this perturbation result in a significant change in ZP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of KIAA0922. Does this perturbation cause a significant change in KIAA0922 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of KIAA0922. Does this perturbation cause a significant change in KIAA0922 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in ACSM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in ACSM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of EIF4B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of EIF4B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and RSAD2 expression is measured. Determine whether RSAD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and RSAD2 expression is measured. Determine whether RSAD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of RP11-838N2.4 is measured. Determine whether RP11-838N2.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of RP11-838N2.4 is measured. Determine whether RP11-838N2.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and KIAA1432 expression is measured. Determine whether KIAA1432 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and KIAA1432 expression is measured. Determine whether KIAA1432 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4240,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of LINC01031 is measured. Does this perturbation cause a significant change in LINC01031 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of LINC01031 is measured. Does this perturbation cause a significant change in LINC01031 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of KLF6 is measured. Determine whether KLF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of KLF6 is measured. Determine whether KLF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of ERV3-1 is measured. Determine whether ERV3-1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of ERV3-1 is measured. Determine whether ERV3-1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and RILPL2 expression is measured. Determine whether RILPL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and RILPL2 expression is measured. Determine whether RILPL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and SOBP expression is quantified. Does this perturbation result in a significant change in SOBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and SOBP expression is quantified. Does this perturbation result in a significant change in SOBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3900,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ARHGAP6 is measured. Does this perturbation cause a significant change in ARHGAP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ARHGAP6 is measured. Does this perturbation cause a significant change in ARHGAP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
69,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RIOK3 expression is measured. Determine whether RIOK3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RIOK3 expression is measured. Determine whether RIOK3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3383,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and TRIM38 expression is observed. Does this perturbation lead to a significant difference in TRIM38 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and TRIM38 expression is observed. Does this perturbation lead to a significant difference in TRIM38 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1328,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor NPDC1 expression. Decide whether this perturbation leads to a significant alteration in NPDC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor NPDC1 expression. Decide whether this perturbation leads to a significant alteration in NPDC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of MORF4L2. Does perturbing SEC63 lead to a significant change in MORF4L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of MORF4L2. Does perturbing SEC63 lead to a significant change in MORF4L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of RP11-95O2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of RP11-95O2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of PTBP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of PTBP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in RP11-254F7.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in RP11-254F7.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ZFP36L2. Does perturbing KCTD16 lead to a significant change in ZFP36L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ZFP36L2. Does perturbing KCTD16 lead to a significant change in ZFP36L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and SRP72 expression is quantified. Does this perturbation result in a significant change in SRP72 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and SRP72 expression is quantified. Does this perturbation result in a significant change in SRP72 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and RILPL2 expression is measured. Determine whether RILPL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and RILPL2 expression is measured. Determine whether RILPL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2030,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of RP11-212I21.4 is measured. Does this perturbation cause a significant change in RP11-212I21.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of RP11-212I21.4 is measured. Does this perturbation cause a significant change in RP11-212I21.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in NUFIP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in NUFIP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in RASGRP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in RASGRP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in WHAMM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in WHAMM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of PSORS1C1. Does this perturbation cause a significant change in PSORS1C1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of PSORS1C1. Does this perturbation cause a significant change in PSORS1C1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of AC096559.1. Does perturbing CAD lead to a significant change in AC096559.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of AC096559.1. Does perturbing CAD lead to a significant change in AC096559.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of NPAT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of NPAT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of RP11-227G15.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of RP11-227G15.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of LAMP2. Does perturbing SPCS3 lead to a significant change in LAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of LAMP2. Does perturbing SPCS3 lead to a significant change in LAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3508,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of HLTF. Does this perturbation cause a significant change in HLTF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of HLTF. Does this perturbation cause a significant change in HLTF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
340,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of MS4A6E is measured. Does this perturbation cause a significant change in MS4A6E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of MS4A6E is measured. Does this perturbation cause a significant change in MS4A6E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4058,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor RP11-15E18.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-15E18.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor RP11-15E18.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-15E18.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and CELF6 expression is quantified. Does this perturbation result in a significant change in CELF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and CELF6 expression is quantified. Does this perturbation result in a significant change in CELF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and WHAMM expression is measured. Determine whether WHAMM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and WHAMM expression is measured. Determine whether WHAMM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of CDCA3. Does this perturbation cause a significant change in CDCA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of CDCA3. Does this perturbation cause a significant change in CDCA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of RP11-423O2.5 is measured. Determine whether RP11-423O2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of RP11-423O2.5 is measured. Determine whether RP11-423O2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3790,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of POLR2J3 is measured. Does this perturbation cause a significant change in POLR2J3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of POLR2J3 is measured. Does this perturbation cause a significant change in POLR2J3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and NPAT expression is measured. Determine whether NPAT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and NPAT expression is measured. Determine whether NPAT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RGS20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RGS20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in GLG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in GLG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of ZNF292 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of ZNF292 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3648,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor RP11-3D4.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-3D4.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor RP11-3D4.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-3D4.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of HM13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of HM13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3143,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and DYNC1H1 expression is observed. Does this perturbation lead to a significant difference in DYNC1H1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and DYNC1H1 expression is observed. Does this perturbation lead to a significant difference in DYNC1H1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in HERC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in HERC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of DSC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of DSC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and C6orf120 expression is measured. Determine whether C6orf120 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and C6orf120 expression is measured. Determine whether C6orf120 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4218,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor CD46 expression. Decide whether this perturbation leads to a significant alteration in CD46 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor CD46 expression. Decide whether this perturbation leads to a significant alteration in CD46 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3610,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of TIPARP is measured. Does this perturbation cause a significant change in TIPARP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of TIPARP is measured. Does this perturbation cause a significant change in TIPARP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of AC015987.2 is measured. Determine whether AC015987.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of AC015987.2 is measured. Determine whether AC015987.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of GS1-166A23.1 is measured. Determine whether GS1-166A23.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of GS1-166A23.1 is measured. Determine whether GS1-166A23.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3000,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of QSER1 is measured. Does this perturbation cause a significant change in QSER1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of QSER1 is measured. Does this perturbation cause a significant change in QSER1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of LINC01031. Does this perturbation cause a significant change in LINC01031 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of LINC01031. Does this perturbation cause a significant change in LINC01031 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of TROAP is measured. Determine whether TROAP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of TROAP is measured. Determine whether TROAP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4170,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of FGF11 is measured. Does this perturbation cause a significant change in FGF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of FGF11 is measured. Does this perturbation cause a significant change in FGF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of LINC00938. Does this perturbation cause a significant change in LINC00938 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of LINC00938. Does this perturbation cause a significant change in LINC00938 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RAI14 is measured. Determine whether RAI14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RAI14 is measured. Determine whether RAI14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of DDX3X indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of DDX3X indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in SETX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in SETX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3698,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor TTC18 expression. Decide whether this perturbation leads to a significant alteration in TTC18 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor TTC18 expression. Decide whether this perturbation leads to a significant alteration in TTC18 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
34,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of CASP4. Does this perturbation cause a significant change in CASP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of CASP4. Does this perturbation cause a significant change in CASP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3260,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of HLA-E is measured. Does this perturbation cause a significant change in HLA-E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of HLA-E is measured. Does this perturbation cause a significant change in HLA-E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4878,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor S100A10 expression. Decide whether this perturbation leads to a significant alteration in S100A10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor S100A10 expression. Decide whether this perturbation leads to a significant alteration in S100A10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
9,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and ZNF429 expression is measured. Determine whether ZNF429 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and ZNF429 expression is measured. Determine whether ZNF429 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in S100A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in S100A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of PPP1R16B. Does perturbing YIPF5 lead to a significant change in PPP1R16B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of PPP1R16B. Does perturbing YIPF5 lead to a significant change in PPP1R16B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5023,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and RP11-430H10.1 expression is observed. Does this perturbation lead to a significant difference in RP11-430H10.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and RP11-430H10.1 expression is observed. Does this perturbation lead to a significant difference in RP11-430H10.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4990,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of ZCCHC11 is measured. Does this perturbation cause a significant change in ZCCHC11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of ZCCHC11 is measured. Does this perturbation cause a significant change in ZCCHC11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in NFE2L3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in NFE2L3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4333,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and GRN expression is observed. Does this perturbation lead to a significant difference in GRN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and GRN expression is observed. Does this perturbation lead to a significant difference in GRN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of TOB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of TOB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of RP11-15E18.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of RP11-15E18.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4270,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of IDS is measured. Does this perturbation cause a significant change in IDS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of IDS is measured. Does this perturbation cause a significant change in IDS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
50,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of C6orf48 is measured. Does this perturbation cause a significant change in C6orf48 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of C6orf48 is measured. Does this perturbation cause a significant change in C6orf48 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of ITGB2. Does perturbing QARS lead to a significant change in ITGB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of ITGB2. Does perturbing QARS lead to a significant change in ITGB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
75,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in CEBPG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in CEBPG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of HOTAIRM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of HOTAIRM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and PELO expression is quantified. Does this perturbation result in a significant change in PELO expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and PELO expression is quantified. Does this perturbation result in a significant change in PELO expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of PCK2 is measured. Determine whether PCK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of PCK2 is measured. Determine whether PCK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and PITPNB expression is measured. Determine whether PITPNB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and PITPNB expression is measured. Determine whether PITPNB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4348,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor HIST1H1D expression. Decide whether this perturbation leads to a significant alteration in HIST1H1D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor HIST1H1D expression. Decide whether this perturbation leads to a significant alteration in HIST1H1D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2528,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor RNF139-AS1 expression. Decide whether this perturbation leads to a significant alteration in RNF139-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor RNF139-AS1 expression. Decide whether this perturbation leads to a significant alteration in RNF139-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of MARCH8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of MARCH8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of PGM3 is measured. Determine whether PGM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of PGM3 is measured. Determine whether PGM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of C19orf59. Does this perturbation cause a significant change in C19orf59 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of C19orf59. Does this perturbation cause a significant change in C19orf59 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and PDRG1 expression is quantified. Does this perturbation result in a significant change in PDRG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and PDRG1 expression is quantified. Does this perturbation result in a significant change in PDRG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of ZFHX3. Does perturbing AARS lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of ZFHX3. Does perturbing AARS lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of ARSA is measured. Determine whether ARSA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of ARSA is measured. Determine whether ARSA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of SPEN is measured. Determine whether SPEN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of SPEN is measured. Determine whether SPEN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
298,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor ATP11B expression. Decide whether this perturbation leads to a significant alteration in ATP11B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor ATP11B expression. Decide whether this perturbation leads to a significant alteration in ATP11B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
200,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of KLK1 is measured. Does this perturbation cause a significant change in KLK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of KLK1 is measured. Does this perturbation cause a significant change in KLK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2938,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor RP11-227G15.8 expression. Decide whether this perturbation leads to a significant alteration in RP11-227G15.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor RP11-227G15.8 expression. Decide whether this perturbation leads to a significant alteration in RP11-227G15.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of IDH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of IDH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of MS4A6E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of MS4A6E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
503,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and PTPN11 expression is observed. Does this perturbation lead to a significant difference in PTPN11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and PTPN11 expression is observed. Does this perturbation lead to a significant difference in PTPN11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of MEX3B is measured. Determine whether MEX3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of MEX3B is measured. Determine whether MEX3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3183,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and RNF8 expression is observed. Does this perturbation lead to a significant difference in RNF8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and RNF8 expression is observed. Does this perturbation lead to a significant difference in RNF8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2453,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and CTNNB1 expression is observed. Does this perturbation lead to a significant difference in CTNNB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and CTNNB1 expression is observed. Does this perturbation lead to a significant difference in CTNNB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2523,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and RNF139-AS1 expression is observed. Does this perturbation lead to a significant difference in RNF139-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and RNF139-AS1 expression is observed. Does this perturbation lead to a significant difference in RNF139-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
493,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and LDLR expression is observed. Does this perturbation lead to a significant difference in LDLR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and LDLR expression is observed. Does this perturbation lead to a significant difference in LDLR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of RP11-838N2.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of RP11-838N2.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of GNPTG. Does perturbing SARS lead to a significant change in GNPTG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of GNPTG. Does perturbing SARS lead to a significant change in GNPTG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1400,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of GUSB is measured. Does this perturbation cause a significant change in GUSB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of GUSB is measured. Does this perturbation cause a significant change in GUSB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of GATA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of GATA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4720,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of RP11-322J23.1 is measured. Does this perturbation cause a significant change in RP11-322J23.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of RP11-322J23.1 is measured. Does this perturbation cause a significant change in RP11-322J23.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of THBS1. Does perturbing P4HB lead to a significant change in THBS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of THBS1. Does perturbing P4HB lead to a significant change in THBS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in RDH10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in RDH10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ARHGAP5 expression is measured. Determine whether ARHGAP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ARHGAP5 expression is measured. Determine whether ARHGAP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1868,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor TACC3 expression. Decide whether this perturbation leads to a significant alteration in TACC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor TACC3 expression. Decide whether this perturbation leads to a significant alteration in TACC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1900,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of AC008074.3 is measured. Does this perturbation cause a significant change in AC008074.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of AC008074.3 is measured. Does this perturbation cause a significant change in AC008074.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of FAM212A is measured. Determine whether FAM212A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of FAM212A is measured. Determine whether FAM212A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5000,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of QSER1 is measured. Does this perturbation cause a significant change in QSER1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of QSER1 is measured. Does this perturbation cause a significant change in QSER1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2763,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and CDK13 expression is observed. Does this perturbation lead to a significant difference in CDK13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and CDK13 expression is observed. Does this perturbation lead to a significant difference in CDK13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of WHAMM. Does this perturbation cause a significant change in WHAMM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of WHAMM. Does this perturbation cause a significant change in WHAMM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and CD83 expression is measured. Determine whether CD83 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and CD83 expression is measured. Determine whether CD83 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of HERPUD1 is measured. Determine whether HERPUD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of HERPUD1 is measured. Determine whether HERPUD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4708,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor LTB expression. Decide whether this perturbation leads to a significant alteration in LTB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor LTB expression. Decide whether this perturbation leads to a significant alteration in LTB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3538,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor FCGRT expression. Decide whether this perturbation leads to a significant alteration in FCGRT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor FCGRT expression. Decide whether this perturbation leads to a significant alteration in FCGRT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of RP11-789C1.1 is measured. Determine whether RP11-789C1.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of RP11-789C1.1 is measured. Determine whether RP11-789C1.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4043,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and SNHG7 expression is observed. Does this perturbation lead to a significant difference in SNHG7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and SNHG7 expression is observed. Does this perturbation lead to a significant difference in SNHG7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of PELO. Does this perturbation cause a significant change in PELO expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of PELO. Does this perturbation cause a significant change in PELO expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of DNASE2. Does this perturbation cause a significant change in DNASE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of DNASE2. Does this perturbation cause a significant change in DNASE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and GOT1 expression is quantified. Does this perturbation result in a significant change in GOT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and GOT1 expression is quantified. Does this perturbation result in a significant change in GOT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and GALNT7 expression is quantified. Does this perturbation result in a significant change in GALNT7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and GALNT7 expression is quantified. Does this perturbation result in a significant change in GALNT7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4918,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor CMTM6 expression. Decide whether this perturbation leads to a significant alteration in CMTM6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor CMTM6 expression. Decide whether this perturbation leads to a significant alteration in CMTM6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in ERV3-1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in ERV3-1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and AC007038.7 expression is measured. Determine whether AC007038.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and AC007038.7 expression is measured. Determine whether AC007038.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of PBDC1. Does this perturbation cause a significant change in PBDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of PBDC1. Does this perturbation cause a significant change in PBDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RGS20 expression is quantified. Does this perturbation result in a significant change in RGS20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RGS20 expression is quantified. Does this perturbation result in a significant change in RGS20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and SEPT5 expression is measured. Determine whether SEPT5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and SEPT5 expression is measured. Determine whether SEPT5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and P4HB expression is measured. Determine whether P4HB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and P4HB expression is measured. Determine whether P4HB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1640,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of SERPINH1 is measured. Does this perturbation cause a significant change in SERPINH1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of SERPINH1 is measured. Does this perturbation cause a significant change in SERPINH1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of QSER1. Does this perturbation cause a significant change in QSER1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of QSER1. Does this perturbation cause a significant change in QSER1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2568,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor SBF2 expression. Decide whether this perturbation leads to a significant alteration in SBF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor SBF2 expression. Decide whether this perturbation leads to a significant alteration in SBF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of HERPUD1. Does this perturbation cause a significant change in HERPUD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of HERPUD1. Does this perturbation cause a significant change in HERPUD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3490,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of DST is measured. Does this perturbation cause a significant change in DST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of DST is measured. Does this perturbation cause a significant change in DST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4650,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of KIAA1586 is measured. Does this perturbation cause a significant change in KIAA1586 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of KIAA1586 is measured. Does this perturbation cause a significant change in KIAA1586 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and CENPC expression is quantified. Does this perturbation result in a significant change in CENPC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and CENPC expression is quantified. Does this perturbation result in a significant change in CENPC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3010,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of PCK2 is measured. Does this perturbation cause a significant change in PCK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of PCK2 is measured. Does this perturbation cause a significant change in PCK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of RCBTB2. Does perturbing STT3A lead to a significant change in RCBTB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of RCBTB2. Does perturbing STT3A lead to a significant change in RCBTB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and KIAA1586 expression is measured. Determine whether KIAA1586 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and KIAA1586 expression is measured. Determine whether KIAA1586 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
978,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor VIMP expression. Decide whether this perturbation leads to a significant alteration in VIMP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor VIMP expression. Decide whether this perturbation leads to a significant alteration in VIMP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1630,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of DNASE2 is measured. Does this perturbation cause a significant change in DNASE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of DNASE2 is measured. Does this perturbation cause a significant change in DNASE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in RP11-95O2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in RP11-95O2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of DUSP21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of DUSP21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1228,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor UBE3A expression. Decide whether this perturbation leads to a significant alteration in UBE3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor UBE3A expression. Decide whether this perturbation leads to a significant alteration in UBE3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3040,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of C10orf32 is measured. Does this perturbation cause a significant change in C10orf32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of C10orf32 is measured. Does this perturbation cause a significant change in C10orf32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in RP11-146D12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in RP11-146D12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and NPAT expression is quantified. Does this perturbation result in a significant change in NPAT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and NPAT expression is quantified. Does this perturbation result in a significant change in NPAT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and LINC01137 expression is quantified. Does this perturbation result in a significant change in LINC01137 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and LINC01137 expression is quantified. Does this perturbation result in a significant change in LINC01137 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of RP11-157D23.2. Does this perturbation cause a significant change in RP11-157D23.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of RP11-157D23.2. Does this perturbation cause a significant change in RP11-157D23.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and PDRG1 expression is measured. Determine whether PDRG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and PDRG1 expression is measured. Determine whether PDRG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of RP11-242O24.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of RP11-242O24.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and HLA-AS1 expression is measured. Determine whether HLA-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and HLA-AS1 expression is measured. Determine whether HLA-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and RP11-242O24.5 expression is quantified. Does this perturbation result in a significant change in RP11-242O24.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and RP11-242O24.5 expression is quantified. Does this perturbation result in a significant change in RP11-242O24.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of SNHG12. Does perturbing AMIGO3 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of SNHG12. Does perturbing AMIGO3 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4178,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor FGF11 expression. Decide whether this perturbation leads to a significant alteration in FGF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor FGF11 expression. Decide whether this perturbation leads to a significant alteration in FGF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3660,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of EP400 is measured. Does this perturbation cause a significant change in EP400 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of EP400 is measured. Does this perturbation cause a significant change in EP400 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and EP300 expression is measured. Determine whether EP300 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and EP300 expression is measured. Determine whether EP300 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in NTRK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in NTRK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4383,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and GALNT7 expression is observed. Does this perturbation lead to a significant difference in GALNT7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and GALNT7 expression is observed. Does this perturbation lead to a significant difference in GALNT7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5118,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor GATA2 expression. Decide whether this perturbation leads to a significant alteration in GATA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor GATA2 expression. Decide whether this perturbation leads to a significant alteration in GATA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of RGS20 is measured. Determine whether RGS20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of RGS20 is measured. Determine whether RGS20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of SPAST is measured. Determine whether SPAST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of SPAST is measured. Determine whether SPAST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of EPB42 is measured. Determine whether EPB42 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of EPB42 is measured. Determine whether EPB42 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of CPQ. Does perturbing ASCC3 lead to a significant change in CPQ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of CPQ. Does perturbing ASCC3 lead to a significant change in CPQ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of C1GALT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of C1GALT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of C6orf120 is measured. Determine whether C6orf120 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of C6orf120 is measured. Determine whether C6orf120 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3893,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and ACRV1 expression is observed. Does this perturbation lead to a significant difference in ACRV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and ACRV1 expression is observed. Does this perturbation lead to a significant difference in ACRV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of RP11-499F3.2. Does this perturbation cause a significant change in RP11-499F3.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of RP11-499F3.2. Does this perturbation cause a significant change in RP11-499F3.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in PRRC2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in PRRC2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in EP400 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in EP400 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of KCNH7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of KCNH7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5038,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor CELF6 expression. Decide whether this perturbation leads to a significant alteration in CELF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor CELF6 expression. Decide whether this perturbation leads to a significant alteration in CELF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3910,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of TFPI is measured. Does this perturbation cause a significant change in TFPI expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of TFPI is measured. Does this perturbation cause a significant change in TFPI expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of RP11-390B4.5. Does this perturbation cause a significant change in RP11-390B4.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of RP11-390B4.5. Does this perturbation cause a significant change in RP11-390B4.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of MARCH8. Does perturbing SAMM50 lead to a significant change in MARCH8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of MARCH8. Does perturbing SAMM50 lead to a significant change in MARCH8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and GNPTG expression is quantified. Does this perturbation result in a significant change in GNPTG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and GNPTG expression is quantified. Does this perturbation result in a significant change in GNPTG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
908,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor PRRC2B expression. Decide whether this perturbation leads to a significant alteration in PRRC2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor PRRC2B expression. Decide whether this perturbation leads to a significant alteration in PRRC2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
630,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of VPS41 is measured. Does this perturbation cause a significant change in VPS41 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of VPS41 is measured. Does this perturbation cause a significant change in VPS41 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4140,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of RILPL2 is measured. Does this perturbation cause a significant change in RILPL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of RILPL2 is measured. Does this perturbation cause a significant change in RILPL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of DUT is measured. Determine whether DUT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of DUT is measured. Determine whether DUT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of PLB1 is measured. Determine whether PLB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of PLB1 is measured. Determine whether PLB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and PDE3B expression is measured. Determine whether PDE3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and PDE3B expression is measured. Determine whether PDE3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of CD83 is measured. Determine whether CD83 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of CD83 is measured. Determine whether CD83 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of RP11-573D15.9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of RP11-573D15.9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of SAMM50 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of SAMM50 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of NFAT5. Does this perturbation cause a significant change in NFAT5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of NFAT5. Does this perturbation cause a significant change in NFAT5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of FGF11 is measured. Determine whether FGF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of FGF11 is measured. Determine whether FGF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in SEC23IP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in SEC23IP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
49,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and LPAR5 expression is measured. Determine whether LPAR5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and LPAR5 expression is measured. Determine whether LPAR5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and VPS41 expression is measured. Determine whether VPS41 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and VPS41 expression is measured. Determine whether VPS41 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2710,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RGS20 is measured. Does this perturbation cause a significant change in RGS20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RGS20 is measured. Does this perturbation cause a significant change in RGS20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of CFH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of CFH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and PELO expression is quantified. Does this perturbation result in a significant change in PELO expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and PELO expression is quantified. Does this perturbation result in a significant change in PELO expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of CDT1. Does this perturbation cause a significant change in CDT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of CDT1. Does this perturbation cause a significant change in CDT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
528,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor DDX6 expression. Decide whether this perturbation leads to a significant alteration in DDX6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor DDX6 expression. Decide whether this perturbation leads to a significant alteration in DDX6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of KCNJ13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of KCNJ13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3390,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of TUBA1C is measured. Does this perturbation cause a significant change in TUBA1C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of TUBA1C is measured. Does this perturbation cause a significant change in TUBA1C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2343,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and C19orf59 expression is observed. Does this perturbation lead to a significant difference in C19orf59 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and C19orf59 expression is observed. Does this perturbation lead to a significant difference in C19orf59 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
358,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor IL18R1 expression. Decide whether this perturbation leads to a significant alteration in IL18R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor IL18R1 expression. Decide whether this perturbation leads to a significant alteration in IL18R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of MORC2-AS1. Does perturbing FARSB lead to a significant change in MORC2-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of MORC2-AS1. Does perturbing FARSB lead to a significant change in MORC2-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and BAMBI expression is measured. Determine whether BAMBI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and BAMBI expression is measured. Determine whether BAMBI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2743,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and DUSP21 expression is observed. Does this perturbation lead to a significant difference in DUSP21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and DUSP21 expression is observed. Does this perturbation lead to a significant difference in DUSP21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1750,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of ARHGAP6 is measured. Does this perturbation cause a significant change in ARHGAP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of ARHGAP6 is measured. Does this perturbation cause a significant change in ARHGAP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
403,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and RP11-90P5.2 expression is observed. Does this perturbation lead to a significant difference in RP11-90P5.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and RP11-90P5.2 expression is observed. Does this perturbation lead to a significant difference in RP11-90P5.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of TOB2 is measured. Determine whether TOB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of TOB2 is measured. Determine whether TOB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of PSMC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of PSMC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of SDF4. Does perturbing MTHFD1 lead to a significant change in SDF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of SDF4. Does perturbing MTHFD1 lead to a significant change in SDF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of EBI3 is measured. Determine whether EBI3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of EBI3 is measured. Determine whether EBI3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in HIST1H1E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in HIST1H1E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and UQCRB expression is quantified. Does this perturbation result in a significant change in UQCRB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and UQCRB expression is quantified. Does this perturbation result in a significant change in UQCRB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
853,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and ATF6 expression is observed. Does this perturbation lead to a significant difference in ATF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and ATF6 expression is observed. Does this perturbation lead to a significant difference in ATF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4823,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and NFE2L3 expression is observed. Does this perturbation lead to a significant difference in NFE2L3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and NFE2L3 expression is observed. Does this perturbation lead to a significant difference in NFE2L3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of QSER1. Does perturbing SEC61G lead to a significant change in QSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of QSER1. Does perturbing SEC61G lead to a significant change in QSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4048,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor SNHG7 expression. Decide whether this perturbation leads to a significant alteration in SNHG7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor SNHG7 expression. Decide whether this perturbation leads to a significant alteration in SNHG7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3493,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and DST expression is observed. Does this perturbation lead to a significant difference in DST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and DST expression is observed. Does this perturbation lead to a significant difference in DST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3090,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of GNPTG is measured. Does this perturbation cause a significant change in GNPTG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of GNPTG is measured. Does this perturbation cause a significant change in GNPTG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of SEPT5 is measured. Determine whether SEPT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of SEPT5 is measured. Determine whether SEPT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of IL8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of IL8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of IL18R1. Does this perturbation cause a significant change in IL18R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of IL18R1. Does this perturbation cause a significant change in IL18R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of PCF11. Does perturbing SPCS3 lead to a significant change in PCF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of PCF11. Does perturbing SPCS3 lead to a significant change in PCF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
970,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of VIMP is measured. Does this perturbation cause a significant change in VIMP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of VIMP is measured. Does this perturbation cause a significant change in VIMP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of ARHGAP6. Does perturbing MTHFD1 lead to a significant change in ARHGAP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of ARHGAP6. Does perturbing MTHFD1 lead to a significant change in ARHGAP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of SP100 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of SP100 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of BOLA3. Does perturbing EIF2B3 lead to a significant change in BOLA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of BOLA3. Does perturbing EIF2B3 lead to a significant change in BOLA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
510,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of PDE4D is measured. Does this perturbation cause a significant change in PDE4D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of PDE4D is measured. Does this perturbation cause a significant change in PDE4D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of CTSV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of CTSV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3338,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor AP000688.8 expression. Decide whether this perturbation leads to a significant alteration in AP000688.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor AP000688.8 expression. Decide whether this perturbation leads to a significant alteration in AP000688.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
660,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of PTBP3 is measured. Does this perturbation cause a significant change in PTBP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of PTBP3 is measured. Does this perturbation cause a significant change in PTBP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of KANSL1L. Does perturbing HARS lead to a significant change in KANSL1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of KANSL1L. Does perturbing HARS lead to a significant change in KANSL1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1593,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and LBX1 expression is observed. Does this perturbation lead to a significant difference in LBX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and LBX1 expression is observed. Does this perturbation lead to a significant difference in LBX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
183,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and STC2 expression is observed. Does this perturbation lead to a significant difference in STC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and STC2 expression is observed. Does this perturbation lead to a significant difference in STC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of LTB. Does perturbing SEC61A1 lead to a significant change in LTB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of LTB. Does perturbing SEC61A1 lead to a significant change in LTB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and BOLA3 expression is measured. Determine whether BOLA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and BOLA3 expression is measured. Determine whether BOLA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and COPB1 expression is quantified. Does this perturbation result in a significant change in COPB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and COPB1 expression is quantified. Does this perturbation result in a significant change in COPB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1093,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and RP11-328J2.1 expression is observed. Does this perturbation lead to a significant difference in RP11-328J2.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and RP11-328J2.1 expression is observed. Does this perturbation lead to a significant difference in RP11-328J2.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of EIF3A is measured. Determine whether EIF3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of EIF3A is measured. Determine whether EIF3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1078,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor ADAMTS10 expression. Decide whether this perturbation leads to a significant alteration in ADAMTS10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor ADAMTS10 expression. Decide whether this perturbation leads to a significant alteration in ADAMTS10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and GATA2 expression is quantified. Does this perturbation result in a significant change in GATA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and GATA2 expression is quantified. Does this perturbation result in a significant change in GATA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4638,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor BOLA3 expression. Decide whether this perturbation leads to a significant alteration in BOLA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor BOLA3 expression. Decide whether this perturbation leads to a significant alteration in BOLA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of ATF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of ATF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4938,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor ATXN7L3B expression. Decide whether this perturbation leads to a significant alteration in ATXN7L3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor ATXN7L3B expression. Decide whether this perturbation leads to a significant alteration in ATXN7L3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and CDK13 expression is measured. Determine whether CDK13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and CDK13 expression is measured. Determine whether CDK13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2898,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor TOPBP1 expression. Decide whether this perturbation leads to a significant alteration in TOPBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor TOPBP1 expression. Decide whether this perturbation leads to a significant alteration in TOPBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5020,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of RP11-430H10.1 is measured. Does this perturbation cause a significant change in RP11-430H10.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of RP11-430H10.1 is measured. Does this perturbation cause a significant change in RP11-430H10.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of CDK13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of CDK13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in KIAA0922 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in KIAA0922 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4448,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor CTBS expression. Decide whether this perturbation leads to a significant alteration in CTBS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor CTBS expression. Decide whether this perturbation leads to a significant alteration in CTBS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3470,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of BACH2 is measured. Does this perturbation cause a significant change in BACH2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of BACH2 is measured. Does this perturbation cause a significant change in BACH2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of HPCAL1. Does perturbing ASCC3 lead to a significant change in HPCAL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of HPCAL1. Does perturbing ASCC3 lead to a significant change in HPCAL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in P4HA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in P4HA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4553,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and CTC-550B14.7 expression is observed. Does this perturbation lead to a significant difference in CTC-550B14.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and CTC-550B14.7 expression is observed. Does this perturbation lead to a significant difference in CTC-550B14.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of TAP1 is measured. Determine whether TAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of TAP1 is measured. Determine whether TAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of MANF. Does this perturbation cause a significant change in MANF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of MANF. Does this perturbation cause a significant change in MANF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in AMOTL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in AMOTL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of NFE2L3. Does this perturbation cause a significant change in NFE2L3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of NFE2L3. Does this perturbation cause a significant change in NFE2L3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of RP11-390B4.5. Does perturbing XRN1 lead to a significant change in RP11-390B4.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of RP11-390B4.5. Does perturbing XRN1 lead to a significant change in RP11-390B4.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in HAGH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in HAGH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and MED13 expression is quantified. Does this perturbation result in a significant change in MED13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and MED13 expression is quantified. Does this perturbation result in a significant change in MED13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
143,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and RDH10 expression is observed. Does this perturbation lead to a significant difference in RDH10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and RDH10 expression is observed. Does this perturbation lead to a significant difference in RDH10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of PIK3R1. Does this perturbation cause a significant change in PIK3R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of PIK3R1. Does this perturbation cause a significant change in PIK3R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of KIAA1731 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of KIAA1731 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and SKIL expression is quantified. Does this perturbation result in a significant change in SKIL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and SKIL expression is quantified. Does this perturbation result in a significant change in SKIL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and RP11-146D12.2 expression is quantified. Does this perturbation result in a significant change in RP11-146D12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and RP11-146D12.2 expression is quantified. Does this perturbation result in a significant change in RP11-146D12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PIF1 is measured. Determine whether PIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PIF1 is measured. Determine whether PIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in VPS41 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in VPS41 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4243,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and LINC01031 expression is observed. Does this perturbation lead to a significant difference in LINC01031 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and LINC01031 expression is observed. Does this perturbation lead to a significant difference in LINC01031 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and PCK2 expression is quantified. Does this perturbation result in a significant change in PCK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and PCK2 expression is quantified. Does this perturbation result in a significant change in PCK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and EP400 expression is measured. Determine whether EP400 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and EP400 expression is measured. Determine whether EP400 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and IL18R1 expression is quantified. Does this perturbation result in a significant change in IL18R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and IL18R1 expression is quantified. Does this perturbation result in a significant change in IL18R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5018,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor THBS1 expression. Decide whether this perturbation leads to a significant alteration in THBS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor THBS1 expression. Decide whether this perturbation leads to a significant alteration in THBS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of RP11-322J23.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of RP11-322J23.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in ARHGAP11A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in ARHGAP11A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of CTC-550B14.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of CTC-550B14.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
918,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor HIST1H3D expression. Decide whether this perturbation leads to a significant alteration in HIST1H3D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor HIST1H3D expression. Decide whether this perturbation leads to a significant alteration in HIST1H3D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of CENPF is measured. Determine whether CENPF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of CENPF is measured. Determine whether CENPF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in LINC00657 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in LINC00657 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3488,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor PTGS1 expression. Decide whether this perturbation leads to a significant alteration in PTGS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor PTGS1 expression. Decide whether this perturbation leads to a significant alteration in PTGS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2060,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of RTN2 is measured. Does this perturbation cause a significant change in RTN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of RTN2 is measured. Does this perturbation cause a significant change in RTN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2618,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor CLDN11 expression. Decide whether this perturbation leads to a significant alteration in CLDN11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor CLDN11 expression. Decide whether this perturbation leads to a significant alteration in CLDN11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of PIK3R3 is measured. Determine whether PIK3R3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of PIK3R3 is measured. Determine whether PIK3R3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of GPR146. Does perturbing SPCS3 lead to a significant change in GPR146 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of GPR146. Does perturbing SPCS3 lead to a significant change in GPR146 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and KHDC1L expression is quantified. Does this perturbation result in a significant change in KHDC1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and KHDC1L expression is quantified. Does this perturbation result in a significant change in KHDC1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4318,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor MED13 expression. Decide whether this perturbation leads to a significant alteration in MED13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor MED13 expression. Decide whether this perturbation leads to a significant alteration in MED13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3243,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and SERPING1 expression is observed. Does this perturbation lead to a significant difference in SERPING1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and SERPING1 expression is observed. Does this perturbation lead to a significant difference in SERPING1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3833,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and PLA2G15 expression is observed. Does this perturbation lead to a significant difference in PLA2G15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and PLA2G15 expression is observed. Does this perturbation lead to a significant difference in PLA2G15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and EIF4B expression is quantified. Does this perturbation result in a significant change in EIF4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and EIF4B expression is quantified. Does this perturbation result in a significant change in EIF4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of ATP6AP2. Does this perturbation cause a significant change in ATP6AP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of ATP6AP2. Does this perturbation cause a significant change in ATP6AP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in C12orf23 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in C12orf23 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of APOBEC3D is measured. Determine whether APOBEC3D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of APOBEC3D is measured. Determine whether APOBEC3D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of TRIM38 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of TRIM38 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of MEX3B. Does perturbing SLMO2 lead to a significant change in MEX3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of MEX3B. Does perturbing SLMO2 lead to a significant change in MEX3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in RP11-81A22.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in RP11-81A22.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2638,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor HAGH expression. Decide whether this perturbation leads to a significant alteration in HAGH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor HAGH expression. Decide whether this perturbation leads to a significant alteration in HAGH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of COPB1. Does perturbing TIMM23 lead to a significant change in COPB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of COPB1. Does perturbing TIMM23 lead to a significant change in COPB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and RSL24D1 expression is measured. Determine whether RSL24D1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and RSL24D1 expression is measured. Determine whether RSL24D1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PSMD14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PSMD14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of ANPEP is measured. Determine whether ANPEP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of ANPEP is measured. Determine whether ANPEP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of ARSA. Does this perturbation cause a significant change in ARSA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of ARSA. Does this perturbation cause a significant change in ARSA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of RP11-430H10.1 is measured. Determine whether RP11-430H10.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of RP11-430H10.1 is measured. Determine whether RP11-430H10.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of TRIM24 is measured. Determine whether TRIM24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of TRIM24 is measured. Determine whether TRIM24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of OR2T6 is measured. Determine whether OR2T6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of OR2T6 is measured. Determine whether OR2T6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of SPINK5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of SPINK5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4520,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of ATF7IP2 is measured. Does this perturbation cause a significant change in ATF7IP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of ATF7IP2 is measured. Does this perturbation cause a significant change in ATF7IP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of PELO is measured. Determine whether PELO shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of PELO is measured. Determine whether PELO shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3263,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and HLA-E expression is observed. Does this perturbation lead to a significant difference in HLA-E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and HLA-E expression is observed. Does this perturbation lead to a significant difference in HLA-E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of RP11-157D23.2. Does perturbing FECH lead to a significant change in RP11-157D23.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of RP11-157D23.2. Does perturbing FECH lead to a significant change in RP11-157D23.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of AMOTL1. Does this perturbation cause a significant change in AMOTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of AMOTL1. Does this perturbation cause a significant change in AMOTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in HLA-E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in HLA-E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and DNASE2 expression is measured. Determine whether DNASE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and DNASE2 expression is measured. Determine whether DNASE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2658,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor IFNGR1 expression. Decide whether this perturbation leads to a significant alteration in IFNGR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor IFNGR1 expression. Decide whether this perturbation leads to a significant alteration in IFNGR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3013,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and PCK2 expression is observed. Does this perturbation lead to a significant difference in PCK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and PCK2 expression is observed. Does this perturbation lead to a significant difference in PCK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of YTHDF2. Does perturbing TMED2 lead to a significant change in YTHDF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of YTHDF2. Does perturbing TMED2 lead to a significant change in YTHDF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and MLEC expression is measured. Determine whether MLEC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and MLEC expression is measured. Determine whether MLEC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of NUFIP2 is measured. Determine whether NUFIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of NUFIP2 is measured. Determine whether NUFIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2603,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and CTCFL expression is observed. Does this perturbation lead to a significant difference in CTCFL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and CTCFL expression is observed. Does this perturbation lead to a significant difference in CTCFL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of VIM-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of VIM-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
573,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and CTD-2001C12.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2001C12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and CTD-2001C12.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2001C12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of ATP2A3. Does perturbing GMPPB lead to a significant change in ATP2A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of ATP2A3. Does perturbing GMPPB lead to a significant change in ATP2A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of GSN is measured. Determine whether GSN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of GSN is measured. Determine whether GSN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of NAV1. Does perturbing PPWD1 lead to a significant change in NAV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of NAV1. Does perturbing PPWD1 lead to a significant change in NAV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of VIMP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of VIMP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of SERPING1. Does perturbing HSPA5 lead to a significant change in SERPING1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of SERPING1. Does perturbing HSPA5 lead to a significant change in SERPING1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of SERPINH1. Does perturbing ATP5B lead to a significant change in SERPINH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of SERPINH1. Does perturbing ATP5B lead to a significant change in SERPINH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3600,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of IL2RB is measured. Does this perturbation cause a significant change in IL2RB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of IL2RB is measured. Does this perturbation cause a significant change in IL2RB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of NSD1. Does this perturbation cause a significant change in NSD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of NSD1. Does this perturbation cause a significant change in NSD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4053,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and RP11-15E18.1 expression is observed. Does this perturbation lead to a significant difference in RP11-15E18.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and RP11-15E18.1 expression is observed. Does this perturbation lead to a significant difference in RP11-15E18.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and RP11-863K10.7 expression is measured. Determine whether RP11-863K10.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and RP11-863K10.7 expression is measured. Determine whether RP11-863K10.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and ARSA expression is measured. Determine whether ARSA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and ARSA expression is measured. Determine whether ARSA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of FGF11. Does perturbing COPB1 lead to a significant change in FGF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of FGF11. Does perturbing COPB1 lead to a significant change in FGF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of RNF139-AS1. Does this perturbation cause a significant change in RNF139-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of RNF139-AS1. Does this perturbation cause a significant change in RNF139-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of GLG1. Does perturbing TMEM167A lead to a significant change in GLG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of GLG1. Does perturbing TMEM167A lead to a significant change in GLG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and KHDC1L expression is measured. Determine whether KHDC1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and KHDC1L expression is measured. Determine whether KHDC1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PSMD14. Does perturbing SARS lead to a significant change in PSMD14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PSMD14. Does perturbing SARS lead to a significant change in PSMD14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of RP11-435O5.4. Does perturbing UFL1 lead to a significant change in RP11-435O5.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of RP11-435O5.4. Does perturbing UFL1 lead to a significant change in RP11-435O5.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of TXNIP. Does perturbing TMED10 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of TXNIP. Does perturbing TMED10 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of PPM1N indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of PPM1N indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4263,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and RASGRP2 expression is observed. Does this perturbation lead to a significant difference in RASGRP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and RASGRP2 expression is observed. Does this perturbation lead to a significant difference in RASGRP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of SSBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of SSBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of CD83. Does this perturbation cause a significant change in CD83 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of CD83. Does this perturbation cause a significant change in CD83 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in MS4A6E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in MS4A6E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1993,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and TLK2 expression is observed. Does this perturbation lead to a significant difference in TLK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and TLK2 expression is observed. Does this perturbation lead to a significant difference in TLK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of PKDCC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of PKDCC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1870,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of AC096559.1 is measured. Does this perturbation cause a significant change in AC096559.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of AC096559.1 is measured. Does this perturbation cause a significant change in AC096559.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of ANKRD11. Does perturbing SEC61G lead to a significant change in ANKRD11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of ANKRD11. Does perturbing SEC61G lead to a significant change in ANKRD11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4393,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and ATAD2B expression is observed. Does this perturbation lead to a significant difference in ATAD2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and ATAD2B expression is observed. Does this perturbation lead to a significant difference in ATAD2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in H3F3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in H3F3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3988,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor PELO expression. Decide whether this perturbation leads to a significant alteration in PELO expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor PELO expression. Decide whether this perturbation leads to a significant alteration in PELO expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in ZNF292 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in ZNF292 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of BAMBI. Does this perturbation cause a significant change in BAMBI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of BAMBI. Does this perturbation cause a significant change in BAMBI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2223,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and GPRC5C expression is observed. Does this perturbation lead to a significant difference in GPRC5C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and GPRC5C expression is observed. Does this perturbation lead to a significant difference in GPRC5C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4180,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of ANKRD33 is measured. Does this perturbation cause a significant change in ANKRD33 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of ANKRD33 is measured. Does this perturbation cause a significant change in ANKRD33 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and HERC2 expression is quantified. Does this perturbation result in a significant change in HERC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and HERC2 expression is quantified. Does this perturbation result in a significant change in HERC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and ATP2A3 expression is quantified. Does this perturbation result in a significant change in ATP2A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and ATP2A3 expression is quantified. Does this perturbation result in a significant change in ATP2A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and NSD1 expression is quantified. Does this perturbation result in a significant change in NSD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and NSD1 expression is quantified. Does this perturbation result in a significant change in NSD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in TSC22D4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in TSC22D4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of EBI3. Does perturbing ATP5B lead to a significant change in EBI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of EBI3. Does perturbing ATP5B lead to a significant change in EBI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3240,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of SERPING1 is measured. Does this perturbation cause a significant change in SERPING1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of SERPING1 is measured. Does this perturbation cause a significant change in SERPING1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1190,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of RP11-435O5.4 is measured. Does this perturbation cause a significant change in RP11-435O5.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of RP11-435O5.4 is measured. Does this perturbation cause a significant change in RP11-435O5.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of PKDCC is measured. Determine whether PKDCC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of PKDCC is measured. Determine whether PKDCC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4583,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and VIMP expression is observed. Does this perturbation lead to a significant difference in VIMP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and VIMP expression is observed. Does this perturbation lead to a significant difference in VIMP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and RAD51AP1 expression is quantified. Does this perturbation result in a significant change in RAD51AP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and RAD51AP1 expression is quantified. Does this perturbation result in a significant change in RAD51AP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and LINC01137 expression is measured. Determine whether LINC01137 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and LINC01137 expression is measured. Determine whether LINC01137 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
513,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and PDE4D expression is observed. Does this perturbation lead to a significant difference in PDE4D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and PDE4D expression is observed. Does this perturbation lead to a significant difference in PDE4D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2968,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor CPQ expression. Decide whether this perturbation leads to a significant alteration in CPQ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor CPQ expression. Decide whether this perturbation leads to a significant alteration in CPQ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of IFNGR1. Does this perturbation cause a significant change in IFNGR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of IFNGR1. Does this perturbation cause a significant change in IFNGR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in SP100 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in SP100 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and ARHGDIB expression is measured. Determine whether ARHGDIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and ARHGDIB expression is measured. Determine whether ARHGDIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in GUSB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in GUSB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in CCDC69 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in CCDC69 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3578,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor APOBEC3D expression. Decide whether this perturbation leads to a significant alteration in APOBEC3D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor APOBEC3D expression. Decide whether this perturbation leads to a significant alteration in APOBEC3D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of TAGLN. Does this perturbation cause a significant change in TAGLN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of TAGLN. Does this perturbation cause a significant change in TAGLN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and ZCCHC11 expression is measured. Determine whether ZCCHC11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and ZCCHC11 expression is measured. Determine whether ZCCHC11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4928,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor YTHDF2 expression. Decide whether this perturbation leads to a significant alteration in YTHDF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor YTHDF2 expression. Decide whether this perturbation leads to a significant alteration in YTHDF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
8,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor ZNF429 expression. Decide whether this perturbation leads to a significant alteration in ZNF429 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor ZNF429 expression. Decide whether this perturbation leads to a significant alteration in ZNF429 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
678,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor MEX3B expression. Decide whether this perturbation leads to a significant alteration in MEX3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor MEX3B expression. Decide whether this perturbation leads to a significant alteration in MEX3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2620,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of MORF4L2 is measured. Does this perturbation cause a significant change in MORF4L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of MORF4L2 is measured. Does this perturbation cause a significant change in MORF4L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of RP11-247A12.2. Does this perturbation cause a significant change in RP11-247A12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of RP11-247A12.2. Does this perturbation cause a significant change in RP11-247A12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and OXLD1 expression is quantified. Does this perturbation result in a significant change in OXLD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and OXLD1 expression is quantified. Does this perturbation result in a significant change in OXLD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in KLK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in KLK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of PDE4D. Does this perturbation cause a significant change in PDE4D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of PDE4D. Does this perturbation cause a significant change in PDE4D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of APOBEC3D. Does this perturbation cause a significant change in APOBEC3D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of APOBEC3D. Does this perturbation cause a significant change in APOBEC3D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of KIAA1432. Does this perturbation cause a significant change in KIAA1432 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of KIAA1432. Does this perturbation cause a significant change in KIAA1432 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ZXDA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ZXDA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of ACRV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of ACRV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and C6orf120 expression is quantified. Does this perturbation result in a significant change in C6orf120 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and C6orf120 expression is quantified. Does this perturbation result in a significant change in C6orf120 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of RP11-363D14.1. Does perturbing EIF2B2 lead to a significant change in RP11-363D14.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of RP11-363D14.1. Does perturbing EIF2B2 lead to a significant change in RP11-363D14.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4600,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of STARD9 is measured. Does this perturbation cause a significant change in STARD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of STARD9 is measured. Does this perturbation cause a significant change in STARD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of AC015987.2. Does perturbing GNPNAT1 lead to a significant change in AC015987.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of AC015987.2. Does perturbing GNPNAT1 lead to a significant change in AC015987.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1490,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of RP11-24F11.2 is measured. Does this perturbation cause a significant change in RP11-24F11.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of RP11-24F11.2 is measured. Does this perturbation cause a significant change in RP11-24F11.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and EIF3A expression is quantified. Does this perturbation result in a significant change in EIF3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and EIF3A expression is quantified. Does this perturbation result in a significant change in EIF3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and SBF2 expression is quantified. Does this perturbation result in a significant change in SBF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and SBF2 expression is quantified. Does this perturbation result in a significant change in SBF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and SEPT5 expression is quantified. Does this perturbation result in a significant change in SEPT5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and SEPT5 expression is quantified. Does this perturbation result in a significant change in SEPT5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4028,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor PIK3R3 expression. Decide whether this perturbation leads to a significant alteration in PIK3R3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor PIK3R3 expression. Decide whether this perturbation leads to a significant alteration in PIK3R3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of STC2 is measured. Determine whether STC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of STC2 is measured. Determine whether STC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and RP11-360L9.8 expression is quantified. Does this perturbation result in a significant change in RP11-360L9.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and RP11-360L9.8 expression is quantified. Does this perturbation result in a significant change in RP11-360L9.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
773,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and JUND expression is observed. Does this perturbation lead to a significant difference in JUND expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and JUND expression is observed. Does this perturbation lead to a significant difference in JUND expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2498,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor CD58 expression. Decide whether this perturbation leads to a significant alteration in CD58 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor CD58 expression. Decide whether this perturbation leads to a significant alteration in CD58 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and CYP17A1-AS1 expression is measured. Determine whether CYP17A1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and CYP17A1-AS1 expression is measured. Determine whether CYP17A1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and SPAST expression is measured. Determine whether SPAST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and SPAST expression is measured. Determine whether SPAST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of C17orf64 is measured. Determine whether C17orf64 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of C17orf64 is measured. Determine whether C17orf64 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in PBDC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in PBDC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of TMOD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of TMOD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of RP11-304M2.5 is measured. Determine whether RP11-304M2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of RP11-304M2.5 is measured. Determine whether RP11-304M2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of DYNC1H1 is measured. Determine whether DYNC1H1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of DYNC1H1 is measured. Determine whether DYNC1H1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of GATA3. Does this perturbation cause a significant change in GATA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of GATA3. Does this perturbation cause a significant change in GATA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3960,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of SETX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of SETX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and NCKAP1L expression is measured. Determine whether NCKAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and NCKAP1L expression is measured. Determine whether NCKAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1903,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and AC008074.3 expression is observed. Does this perturbation lead to a significant difference in AC008074.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and AC008074.3 expression is observed. Does this perturbation lead to a significant difference in AC008074.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of KIAA1432 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of KIAA1432 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of COPB1. Does this perturbation cause a significant change in COPB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of COPB1. Does this perturbation cause a significant change in COPB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5043,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and LAMP2 expression is observed. Does this perturbation lead to a significant difference in LAMP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and LAMP2 expression is observed. Does this perturbation lead to a significant difference in LAMP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in RNF8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in RNF8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and LDLR expression is quantified. Does this perturbation result in a significant change in LDLR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and LDLR expression is quantified. Does this perturbation result in a significant change in LDLR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of WDR72. Does perturbing UFM1 lead to a significant change in WDR72 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of WDR72. Does perturbing UFM1 lead to a significant change in WDR72 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2220,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of GPRC5C is measured. Does this perturbation cause a significant change in GPRC5C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of GPRC5C is measured. Does this perturbation cause a significant change in GPRC5C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of RP11-146D12.2. Does perturbing SRPR lead to a significant change in RP11-146D12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of RP11-146D12.2. Does perturbing SRPR lead to a significant change in RP11-146D12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of LINC00862 is measured. Determine whether LINC00862 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of LINC00862 is measured. Determine whether LINC00862 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2613,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and CLDN11 expression is observed. Does this perturbation lead to a significant difference in CLDN11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and CLDN11 expression is observed. Does this perturbation lead to a significant difference in CLDN11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3438,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ARHGAP5 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ARHGAP5 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of DNMBP. Does this perturbation cause a significant change in DNMBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of DNMBP. Does this perturbation cause a significant change in DNMBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of POLR2J3. Does perturbing HYOU1 lead to a significant change in POLR2J3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of POLR2J3. Does perturbing HYOU1 lead to a significant change in POLR2J3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3103,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PSMD14 expression is observed. Does this perturbation lead to a significant difference in PSMD14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PSMD14 expression is observed. Does this perturbation lead to a significant difference in PSMD14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of BRWD3. Does this perturbation cause a significant change in BRWD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of BRWD3. Does this perturbation cause a significant change in BRWD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of HLA-E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of HLA-E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ZFP36L2 expression is measured. Determine whether ZFP36L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ZFP36L2 expression is measured. Determine whether ZFP36L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2663,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and ASPM expression is observed. Does this perturbation lead to a significant difference in ASPM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and ASPM expression is observed. Does this perturbation lead to a significant difference in ASPM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and SLC37A1 expression is quantified. Does this perturbation result in a significant change in SLC37A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and SLC37A1 expression is quantified. Does this perturbation result in a significant change in SLC37A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2098,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
70,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of CEBPG is measured. Does this perturbation cause a significant change in CEBPG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of CEBPG is measured. Does this perturbation cause a significant change in CEBPG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of GPR146. Does this perturbation cause a significant change in GPR146 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of GPR146. Does this perturbation cause a significant change in GPR146 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of CDKN2C. Does perturbing HSD17B12 lead to a significant change in CDKN2C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of CDKN2C. Does perturbing HSD17B12 lead to a significant change in CDKN2C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in BACH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in BACH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3233,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and RP11-16E12.1 expression is observed. Does this perturbation lead to a significant difference in RP11-16E12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and RP11-16E12.1 expression is observed. Does this perturbation lead to a significant difference in RP11-16E12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of EXO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of EXO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in PDE4D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in PDE4D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and AMOTL1 expression is measured. Determine whether AMOTL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and AMOTL1 expression is measured. Determine whether AMOTL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3220,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of ZNF789 is measured. Does this perturbation cause a significant change in ZNF789 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of ZNF789 is measured. Does this perturbation cause a significant change in ZNF789 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of CDK13. Does this perturbation cause a significant change in CDK13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of CDK13. Does this perturbation cause a significant change in CDK13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in ANKRD10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in ANKRD10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4173,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and FGF11 expression is observed. Does this perturbation lead to a significant difference in FGF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and FGF11 expression is observed. Does this perturbation lead to a significant difference in FGF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of C9orf64. Does perturbing DDOST lead to a significant change in C9orf64 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of C9orf64. Does perturbing DDOST lead to a significant change in C9orf64 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ZFP36L2. Does this perturbation cause a significant change in ZFP36L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ZFP36L2. Does this perturbation cause a significant change in ZFP36L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in GALNT7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in GALNT7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of ZNF292. Does perturbing SRP68 lead to a significant change in ZNF292 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of ZNF292. Does perturbing SRP68 lead to a significant change in ZNF292 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2833,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and EXO1 expression is observed. Does this perturbation lead to a significant difference in EXO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and EXO1 expression is observed. Does this perturbation lead to a significant difference in EXO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of ATP6AP2. Does perturbing ATP5B lead to a significant change in ATP6AP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of ATP6AP2. Does perturbing ATP5B lead to a significant change in ATP6AP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and APOBEC3D expression is quantified. Does this perturbation result in a significant change in APOBEC3D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and APOBEC3D expression is quantified. Does this perturbation result in a significant change in APOBEC3D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of RHCE. Does perturbing SCYL1 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of RHCE. Does perturbing SCYL1 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
903,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and PRRC2B expression is observed. Does this perturbation lead to a significant difference in PRRC2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and PRRC2B expression is observed. Does this perturbation lead to a significant difference in PRRC2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP6 is measured. Determine whether ARHGAP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP6 is measured. Determine whether ARHGAP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in PTBP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in PTBP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and RP11-90P5.2 expression is measured. Determine whether RP11-90P5.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and RP11-90P5.2 expression is measured. Determine whether RP11-90P5.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
733,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and BRWD3 expression is observed. Does this perturbation lead to a significant difference in BRWD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and BRWD3 expression is observed. Does this perturbation lead to a significant difference in BRWD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in AC008074.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in AC008074.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and KANSL1L expression is measured. Determine whether KANSL1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and KANSL1L expression is measured. Determine whether KANSL1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and PCF11 expression is measured. Determine whether PCF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and PCF11 expression is measured. Determine whether PCF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2543,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and ZP3 expression is observed. Does this perturbation lead to a significant difference in ZP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and ZP3 expression is observed. Does this perturbation lead to a significant difference in ZP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of WDR3. Does this perturbation cause a significant change in WDR3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of WDR3. Does this perturbation cause a significant change in WDR3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of RP11-95O2.5. Does this perturbation cause a significant change in RP11-95O2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of RP11-95O2.5. Does this perturbation cause a significant change in RP11-95O2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of EP400. Does this perturbation cause a significant change in EP400 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of EP400. Does this perturbation cause a significant change in EP400 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of BIRC5. Does this perturbation cause a significant change in BIRC5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of BIRC5. Does this perturbation cause a significant change in BIRC5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3953,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and SERPINF2 expression is observed. Does this perturbation lead to a significant difference in SERPINF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and SERPINF2 expression is observed. Does this perturbation lead to a significant difference in SERPINF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1118,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor GOT1 expression. Decide whether this perturbation leads to a significant alteration in GOT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor GOT1 expression. Decide whether this perturbation leads to a significant alteration in GOT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and QSER1 expression is quantified. Does this perturbation result in a significant change in QSER1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and QSER1 expression is quantified. Does this perturbation result in a significant change in QSER1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and AC096559.1 expression is quantified. Does this perturbation result in a significant change in AC096559.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and AC096559.1 expression is quantified. Does this perturbation result in a significant change in AC096559.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of THBS1. Does this perturbation cause a significant change in THBS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of THBS1. Does this perturbation cause a significant change in THBS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2158,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor SNRNP25 expression. Decide whether this perturbation leads to a significant alteration in SNRNP25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor SNRNP25 expression. Decide whether this perturbation leads to a significant alteration in SNRNP25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and CTSF expression is measured. Determine whether CTSF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and CTSF expression is measured. Determine whether CTSF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1768,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor C12orf23 expression. Decide whether this perturbation leads to a significant alteration in C12orf23 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor C12orf23 expression. Decide whether this perturbation leads to a significant alteration in C12orf23 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in ZNF292 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in ZNF292 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of ATP11B is measured. Determine whether ATP11B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of ATP11B is measured. Determine whether ATP11B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of AFF1 is measured. Determine whether AFF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of AFF1 is measured. Determine whether AFF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in PTPN11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in PTPN11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and DDIT4 expression is measured. Determine whether DDIT4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and DDIT4 expression is measured. Determine whether DDIT4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of PPP4R2 is measured. Determine whether PPP4R2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of PPP4R2 is measured. Determine whether PPP4R2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of BACH2. Does perturbing KCTD16 lead to a significant change in BACH2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of BACH2. Does perturbing KCTD16 lead to a significant change in BACH2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of PTAR1 is measured. Determine whether PTAR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of PTAR1 is measured. Determine whether PTAR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
21,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of RUNX1. Does perturbing CREB1 lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of RUNX1. Does perturbing CREB1 lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4100,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of LINC00938 is measured. Does this perturbation cause a significant change in LINC00938 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of LINC00938 is measured. Does this perturbation cause a significant change in LINC00938 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and RP13-216E22.4 expression is quantified. Does this perturbation result in a significant change in RP13-216E22.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and RP13-216E22.4 expression is quantified. Does this perturbation result in a significant change in RP13-216E22.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1618,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor RP11-81A22.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-81A22.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor RP11-81A22.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-81A22.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4888,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor WARS expression. Decide whether this perturbation leads to a significant alteration in WARS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor WARS expression. Decide whether this perturbation leads to a significant alteration in WARS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and PPP1R16B expression is quantified. Does this perturbation result in a significant change in PPP1R16B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and PPP1R16B expression is quantified. Does this perturbation result in a significant change in PPP1R16B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of EXOC3L2 is measured. Determine whether EXOC3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of EXOC3L2 is measured. Determine whether EXOC3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2880,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of RP11-499F3.2 is measured. Does this perturbation cause a significant change in RP11-499F3.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of RP11-499F3.2 is measured. Does this perturbation cause a significant change in RP11-499F3.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and ASPM expression is measured. Determine whether ASPM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and ASPM expression is measured. Determine whether ASPM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in UBE3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in UBE3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in MBNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in MBNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2888,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor RP11-499F3.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-499F3.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor RP11-499F3.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-499F3.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of ABI2. Does this perturbation cause a significant change in ABI2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of ABI2. Does this perturbation cause a significant change in ABI2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and ZNF292 expression is measured. Determine whether ZNF292 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and ZNF292 expression is measured. Determine whether ZNF292 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and GLG1 expression is measured. Determine whether GLG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and GLG1 expression is measured. Determine whether GLG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in TOB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in TOB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1180,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of SETD5-AS1 is measured. Does this perturbation cause a significant change in SETD5-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of SETD5-AS1 is measured. Does this perturbation cause a significant change in SETD5-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RP11-65L19.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RP11-65L19.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and UFD1L expression is measured. Determine whether UFD1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and UFD1L expression is measured. Determine whether UFD1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and UHMK1 expression is measured. Determine whether UHMK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and UHMK1 expression is measured. Determine whether UHMK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and CCRL2 expression is measured. Determine whether CCRL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and CCRL2 expression is measured. Determine whether CCRL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of IL18R1 is measured. Determine whether IL18R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of IL18R1 is measured. Determine whether IL18R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in NBEAL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in NBEAL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3200,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of GSN is measured. Does this perturbation cause a significant change in GSN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of GSN is measured. Does this perturbation cause a significant change in GSN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5093,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and TGOLN2 expression is observed. Does this perturbation lead to a significant difference in TGOLN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and TGOLN2 expression is observed. Does this perturbation lead to a significant difference in TGOLN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and VIMP expression is quantified. Does this perturbation result in a significant change in VIMP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and VIMP expression is quantified. Does this perturbation result in a significant change in VIMP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and TTC32 expression is quantified. Does this perturbation result in a significant change in TTC32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and TTC32 expression is quantified. Does this perturbation result in a significant change in TTC32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and RP11-360L9.8 expression is quantified. Does this perturbation result in a significant change in RP11-360L9.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and RP11-360L9.8 expression is quantified. Does this perturbation result in a significant change in RP11-360L9.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1100,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of ZNF280B is measured. Does this perturbation cause a significant change in ZNF280B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of ZNF280B is measured. Does this perturbation cause a significant change in ZNF280B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2960,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of CPQ is measured. Does this perturbation cause a significant change in CPQ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of CPQ is measured. Does this perturbation cause a significant change in CPQ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
253,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and LINC00657 expression is observed. Does this perturbation lead to a significant difference in LINC00657 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and LINC00657 expression is observed. Does this perturbation lead to a significant difference in LINC00657 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and PAK1IP1 expression is measured. Determine whether PAK1IP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and PAK1IP1 expression is measured. Determine whether PAK1IP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of LAMP2. Does this perturbation cause a significant change in LAMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of LAMP2. Does this perturbation cause a significant change in LAMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in AC015987.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in AC015987.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of HIST1H1E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of HIST1H1E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of PCF11. Does this perturbation cause a significant change in PCF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of PCF11. Does this perturbation cause a significant change in PCF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of AMOTL1. Does perturbing NEDD8 lead to a significant change in AMOTL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of AMOTL1. Does perturbing NEDD8 lead to a significant change in AMOTL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of SPCS2 is measured. Determine whether SPCS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of SPCS2 is measured. Determine whether SPCS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1738,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor USP37 expression. Decide whether this perturbation leads to a significant alteration in USP37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor USP37 expression. Decide whether this perturbation leads to a significant alteration in USP37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
32,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and CASP4 expression is quantified. Does this perturbation result in a significant change in CASP4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and CASP4 expression is quantified. Does this perturbation result in a significant change in CASP4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of RP11-24F11.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of RP11-24F11.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and AC007038.7 expression is quantified. Does this perturbation result in a significant change in AC007038.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and AC007038.7 expression is quantified. Does this perturbation result in a significant change in AC007038.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1508,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor ZNF292 expression. Decide whether this perturbation leads to a significant alteration in ZNF292 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor ZNF292 expression. Decide whether this perturbation leads to a significant alteration in ZNF292 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in AC007038.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in AC007038.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and EP400 expression is quantified. Does this perturbation result in a significant change in EP400 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and EP400 expression is quantified. Does this perturbation result in a significant change in EP400 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4743,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and PAXBP1 expression is observed. Does this perturbation lead to a significant difference in PAXBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and PAXBP1 expression is observed. Does this perturbation lead to a significant difference in PAXBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and FOXO6 expression is quantified. Does this perturbation result in a significant change in FOXO6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and FOXO6 expression is quantified. Does this perturbation result in a significant change in FOXO6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and WHSC1 expression is measured. Determine whether WHSC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and WHSC1 expression is measured. Determine whether WHSC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of UQCRB is measured. Determine whether UQCRB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of UQCRB is measured. Determine whether UQCRB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of ZEB1. Does this perturbation cause a significant change in ZEB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of ZEB1. Does this perturbation cause a significant change in ZEB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2233,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and FAM212A expression is observed. Does this perturbation lead to a significant difference in FAM212A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and FAM212A expression is observed. Does this perturbation lead to a significant difference in FAM212A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in KANSL1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in KANSL1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and PPP1R16B expression is measured. Determine whether PPP1R16B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and PPP1R16B expression is measured. Determine whether PPP1R16B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3810,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of RP11-445H22.3 is measured. Does this perturbation cause a significant change in RP11-445H22.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of RP11-445H22.3 is measured. Does this perturbation cause a significant change in RP11-445H22.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of STARD9 is measured. Determine whether STARD9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of STARD9 is measured. Determine whether STARD9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of P4HA2. Does this perturbation cause a significant change in P4HA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of P4HA2. Does this perturbation cause a significant change in P4HA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of TSNAXIP1. Does this perturbation cause a significant change in TSNAXIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of TSNAXIP1. Does this perturbation cause a significant change in TSNAXIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and HPCAL1 expression is quantified. Does this perturbation result in a significant change in HPCAL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and HPCAL1 expression is quantified. Does this perturbation result in a significant change in HPCAL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of CHD3. Does this perturbation cause a significant change in CHD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of CHD3. Does this perturbation cause a significant change in CHD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and PDE3B expression is quantified. Does this perturbation result in a significant change in PDE3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and PDE3B expression is quantified. Does this perturbation result in a significant change in PDE3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of ZFHX3. Does perturbing SOCS1 lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of ZFHX3. Does perturbing SOCS1 lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of KLF6. Does this perturbation cause a significant change in KLF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of KLF6. Does this perturbation cause a significant change in KLF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2788,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor S100A13 expression. Decide whether this perturbation leads to a significant alteration in S100A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor S100A13 expression. Decide whether this perturbation leads to a significant alteration in S100A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and WARS expression is quantified. Does this perturbation result in a significant change in WARS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and WARS expression is quantified. Does this perturbation result in a significant change in WARS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
993,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and SHOX2 expression is observed. Does this perturbation lead to a significant difference in SHOX2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and SHOX2 expression is observed. Does this perturbation lead to a significant difference in SHOX2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3590,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of RP11-2H8.2 is measured. Does this perturbation cause a significant change in RP11-2H8.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of RP11-2H8.2 is measured. Does this perturbation cause a significant change in RP11-2H8.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and SPINK5 expression is quantified. Does this perturbation result in a significant change in SPINK5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and SPINK5 expression is quantified. Does this perturbation result in a significant change in SPINK5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ARHGAP6. Does this perturbation cause a significant change in ARHGAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ARHGAP6. Does this perturbation cause a significant change in ARHGAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3868,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor TNFRSF10B expression. Decide whether this perturbation leads to a significant alteration in TNFRSF10B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor TNFRSF10B expression. Decide whether this perturbation leads to a significant alteration in TNFRSF10B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1623,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and ATP6AP2 expression is observed. Does this perturbation lead to a significant difference in ATP6AP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and ATP6AP2 expression is observed. Does this perturbation lead to a significant difference in ATP6AP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of SMCO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of SMCO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of AMOTL1 is measured. Determine whether AMOTL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of AMOTL1 is measured. Determine whether AMOTL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in SERPINH1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in SERPINH1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5078,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor ERP29 expression. Decide whether this perturbation leads to a significant alteration in ERP29 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor ERP29 expression. Decide whether this perturbation leads to a significant alteration in ERP29 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of NOSTRIN. Does this perturbation cause a significant change in NOSTRIN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of NOSTRIN. Does this perturbation cause a significant change in NOSTRIN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2813,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and CDKN2C expression is observed. Does this perturbation lead to a significant difference in CDKN2C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and CDKN2C expression is observed. Does this perturbation lead to a significant difference in CDKN2C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of IFT27 is measured. Determine whether IFT27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of IFT27 is measured. Determine whether IFT27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in FGF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in FGF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of IDS. Does perturbing AARS lead to a significant change in IDS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of IDS. Does perturbing AARS lead to a significant change in IDS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in NOSTRIN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in NOSTRIN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4388,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor GALNT7 expression. Decide whether this perturbation leads to a significant alteration in GALNT7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor GALNT7 expression. Decide whether this perturbation leads to a significant alteration in GALNT7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3653,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and KCNJ13 expression is observed. Does this perturbation lead to a significant difference in KCNJ13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and KCNJ13 expression is observed. Does this perturbation lead to a significant difference in KCNJ13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and RTN2 expression is measured. Determine whether RTN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and RTN2 expression is measured. Determine whether RTN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3780,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of LTN1 is measured. Does this perturbation cause a significant change in LTN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of LTN1 is measured. Does this perturbation cause a significant change in LTN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and C19orf59 expression is measured. Determine whether C19orf59 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and C19orf59 expression is measured. Determine whether C19orf59 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of DUT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of DUT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of IL8. Does this perturbation cause a significant change in IL8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of IL8. Does this perturbation cause a significant change in IL8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2680,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of KCTD19 is measured. Does this perturbation cause a significant change in KCTD19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of KCTD19 is measured. Does this perturbation cause a significant change in KCTD19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and PCF11 expression is quantified. Does this perturbation result in a significant change in PCF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and PCF11 expression is quantified. Does this perturbation result in a significant change in PCF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in C12orf44 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in C12orf44 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and RP11-430H10.1 expression is measured. Determine whether RP11-430H10.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and RP11-430H10.1 expression is measured. Determine whether RP11-430H10.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1210,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of JARID2 is measured. Does this perturbation cause a significant change in JARID2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of JARID2 is measured. Does this perturbation cause a significant change in JARID2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of DDIT4 is measured. Determine whether DDIT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of DDIT4 is measured. Determine whether DDIT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4758,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of RASGRP2 is measured. Determine whether RASGRP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of RASGRP2 is measured. Determine whether RASGRP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of HOTAIRM1. Does this perturbation cause a significant change in HOTAIRM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of HOTAIRM1. Does this perturbation cause a significant change in HOTAIRM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of LTBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of LTBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4490,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of SMCO1 is measured. Does this perturbation cause a significant change in SMCO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of SMCO1 is measured. Does this perturbation cause a significant change in SMCO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of COPB1 is measured. Determine whether COPB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of COPB1 is measured. Determine whether COPB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of APOL4 is measured. Determine whether APOL4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of APOL4 is measured. Determine whether APOL4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of IL32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of IL32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2893,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and TOPBP1 expression is observed. Does this perturbation lead to a significant difference in TOPBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and TOPBP1 expression is observed. Does this perturbation lead to a significant difference in TOPBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of AC104532.4 is measured. Determine whether AC104532.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of AC104532.4 is measured. Determine whether AC104532.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2980,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of AC104532.4 is measured. Does this perturbation cause a significant change in AC104532.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of AC104532.4 is measured. Does this perturbation cause a significant change in AC104532.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and HOTAIRM1 expression is quantified. Does this perturbation result in a significant change in HOTAIRM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and HOTAIRM1 expression is quantified. Does this perturbation result in a significant change in HOTAIRM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3168,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor MT2A expression. Decide whether this perturbation leads to a significant alteration in MT2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor MT2A expression. Decide whether this perturbation leads to a significant alteration in MT2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and SLC26A1 expression is measured. Determine whether SLC26A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and SLC26A1 expression is measured. Determine whether SLC26A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4353,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and ANKRD10 expression is observed. Does this perturbation lead to a significant difference in ANKRD10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and ANKRD10 expression is observed. Does this perturbation lead to a significant difference in ANKRD10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in ZEB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in ZEB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1880,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of SNHG10 is measured. Does this perturbation cause a significant change in SNHG10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of SNHG10 is measured. Does this perturbation cause a significant change in SNHG10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and CDT1 expression is quantified. Does this perturbation result in a significant change in CDT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and CDT1 expression is quantified. Does this perturbation result in a significant change in CDT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2340,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of C19orf59 is measured. Does this perturbation cause a significant change in C19orf59 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of C19orf59 is measured. Does this perturbation cause a significant change in C19orf59 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in WDR3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in WDR3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of TROAP. Does this perturbation cause a significant change in TROAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of TROAP. Does this perturbation cause a significant change in TROAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of TNFRSF10B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of TNFRSF10B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3408,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor C3AR1 expression. Decide whether this perturbation leads to a significant alteration in C3AR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor C3AR1 expression. Decide whether this perturbation leads to a significant alteration in C3AR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and CDT1 expression is measured. Determine whether CDT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and CDT1 expression is measured. Determine whether CDT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of ZP3. Does perturbing FARSB lead to a significant change in ZP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of ZP3. Does perturbing FARSB lead to a significant change in ZP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of TMOD3 is measured. Determine whether TMOD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of TMOD3 is measured. Determine whether TMOD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and LTN1 expression is measured. Determine whether LTN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and LTN1 expression is measured. Determine whether LTN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of CD46. Does this perturbation cause a significant change in CD46 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of CD46. Does this perturbation cause a significant change in CD46 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of S100A13. Does this perturbation cause a significant change in S100A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of S100A13. Does this perturbation cause a significant change in S100A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of RP11-254F7.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of RP11-254F7.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of KCNJ13 is measured. Determine whether KCNJ13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of KCNJ13 is measured. Determine whether KCNJ13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3333,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and AP000688.8 expression is observed. Does this perturbation lead to a significant difference in AP000688.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and AP000688.8 expression is observed. Does this perturbation lead to a significant difference in AP000688.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of RP11-360L9.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of RP11-360L9.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in PCK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in PCK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1313,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and SNHG10 expression is observed. Does this perturbation lead to a significant difference in SNHG10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and SNHG10 expression is observed. Does this perturbation lead to a significant difference in SNHG10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
373,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and HMGCS1 expression is observed. Does this perturbation lead to a significant difference in HMGCS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and HMGCS1 expression is observed. Does this perturbation lead to a significant difference in HMGCS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in PIK3IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in PIK3IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of TOPBP1 is measured. Determine whether TOPBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of TOPBP1 is measured. Determine whether TOPBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and EPB42 expression is measured. Determine whether EPB42 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and EPB42 expression is measured. Determine whether EPB42 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of KLF3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of KLF3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in RGS20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in RGS20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in RP11-334C17.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in RP11-334C17.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of F2RL2. Does this perturbation cause a significant change in F2RL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of F2RL2. Does this perturbation cause a significant change in F2RL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4478,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor RP11-95O2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-95O2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor RP11-95O2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-95O2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2390,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of RP11-254F7.4 is measured. Does this perturbation cause a significant change in RP11-254F7.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of RP11-254F7.4 is measured. Does this perturbation cause a significant change in RP11-254F7.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
363,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and DOCK11 expression is observed. Does this perturbation lead to a significant difference in DOCK11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and DOCK11 expression is observed. Does this perturbation lead to a significant difference in DOCK11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and ACRV1 expression is measured. Determine whether ACRV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and ACRV1 expression is measured. Determine whether ACRV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of NCKAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of NCKAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of LTN1. Does perturbing HYOU1 lead to a significant change in LTN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of LTN1. Does perturbing HYOU1 lead to a significant change in LTN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3268,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor HLA-E expression. Decide whether this perturbation leads to a significant alteration in HLA-E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor HLA-E expression. Decide whether this perturbation leads to a significant alteration in HLA-E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in HLA-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in HLA-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ACE expression is quantified. Does this perturbation result in a significant change in ACE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ACE expression is quantified. Does this perturbation result in a significant change in ACE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2798,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor RP11-360L9.8 expression. Decide whether this perturbation leads to a significant alteration in RP11-360L9.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor RP11-360L9.8 expression. Decide whether this perturbation leads to a significant alteration in RP11-360L9.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and UHMK1 expression is quantified. Does this perturbation result in a significant change in UHMK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and UHMK1 expression is quantified. Does this perturbation result in a significant change in UHMK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of AP000688.8. Does perturbing PSMD4 lead to a significant change in AP000688.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of AP000688.8. Does perturbing PSMD4 lead to a significant change in AP000688.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
820,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of TMEM87B is measured. Does this perturbation cause a significant change in TMEM87B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of TMEM87B is measured. Does this perturbation cause a significant change in TMEM87B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in ANKLE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in ANKLE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of KCTD1. Does perturbing STT3A lead to a significant change in KCTD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of KCTD1. Does perturbing STT3A lead to a significant change in KCTD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of SHOX2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of SHOX2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1770,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of SDF4 is measured. Does this perturbation cause a significant change in SDF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of SDF4 is measured. Does this perturbation cause a significant change in SDF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in SLFNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in SLFNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in ZNF280B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in ZNF280B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4673,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and H1FX expression is observed. Does this perturbation lead to a significant difference in H1FX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and H1FX expression is observed. Does this perturbation lead to a significant difference in H1FX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of ZNF678. Does this perturbation cause a significant change in ZNF678 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of ZNF678. Does this perturbation cause a significant change in ZNF678 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2963,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and CPQ expression is observed. Does this perturbation lead to a significant difference in CPQ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and CPQ expression is observed. Does this perturbation lead to a significant difference in CPQ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5010,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of THBS1 is measured. Does this perturbation cause a significant change in THBS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of THBS1 is measured. Does this perturbation cause a significant change in THBS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and SMCO1 expression is quantified. Does this perturbation result in a significant change in SMCO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and SMCO1 expression is quantified. Does this perturbation result in a significant change in SMCO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4633,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and BOLA3 expression is observed. Does this perturbation lead to a significant difference in BOLA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and BOLA3 expression is observed. Does this perturbation lead to a significant difference in BOLA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of ANKRD10 is measured. Determine whether ANKRD10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of ANKRD10 is measured. Determine whether ANKRD10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of PAXBP1 is measured. Determine whether PAXBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of PAXBP1 is measured. Determine whether PAXBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of DNASE2. Does perturbing ATP5B lead to a significant change in DNASE2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of DNASE2. Does perturbing ATP5B lead to a significant change in DNASE2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of PDE3B. Does this perturbation cause a significant change in PDE3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of PDE3B. Does this perturbation cause a significant change in PDE3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2800,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of RILPL2 is measured. Does this perturbation cause a significant change in RILPL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of RILPL2 is measured. Does this perturbation cause a significant change in RILPL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1333,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and RCBTB2 expression is observed. Does this perturbation lead to a significant difference in RCBTB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and RCBTB2 expression is observed. Does this perturbation lead to a significant difference in RCBTB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and APOL4 expression is measured. Determine whether APOL4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and APOL4 expression is measured. Determine whether APOL4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of RP1-274L7.1. Does perturbing CCND3 lead to a significant change in RP1-274L7.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of RP1-274L7.1. Does perturbing CCND3 lead to a significant change in RP1-274L7.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
703,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and UQCRB expression is observed. Does this perturbation lead to a significant difference in UQCRB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and UQCRB expression is observed. Does this perturbation lead to a significant difference in UQCRB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of NOXA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of NOXA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3930,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ZXDA is measured. Does this perturbation cause a significant change in ZXDA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ZXDA is measured. Does this perturbation cause a significant change in ZXDA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in UHMK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in UHMK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of KHDC1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of KHDC1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2858,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor OXLD1 expression. Decide whether this perturbation leads to a significant alteration in OXLD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor OXLD1 expression. Decide whether this perturbation leads to a significant alteration in OXLD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and TAGLN expression is measured. Determine whether TAGLN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and TAGLN expression is measured. Determine whether TAGLN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of NTRK1. Does this perturbation cause a significant change in NTRK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of NTRK1. Does this perturbation cause a significant change in NTRK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and AFF1 expression is measured. Determine whether AFF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and AFF1 expression is measured. Determine whether AFF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and GPRC5C expression is measured. Determine whether GPRC5C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and GPRC5C expression is measured. Determine whether GPRC5C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2838,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor EXO1 expression. Decide whether this perturbation leads to a significant alteration in EXO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor EXO1 expression. Decide whether this perturbation leads to a significant alteration in EXO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of F2RL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of F2RL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
823,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and TMEM87B expression is observed. Does this perturbation lead to a significant difference in TMEM87B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and TMEM87B expression is observed. Does this perturbation lead to a significant difference in TMEM87B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of TMOD3. Does perturbing SEL1L lead to a significant change in TMOD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of TMOD3. Does perturbing SEL1L lead to a significant change in TMOD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and PTGS1 expression is quantified. Does this perturbation result in a significant change in PTGS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and PTGS1 expression is quantified. Does this perturbation result in a significant change in PTGS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of SETD5-AS1. Does this perturbation cause a significant change in SETD5-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of SETD5-AS1. Does this perturbation cause a significant change in SETD5-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of KIAA1432. Does perturbing PTDSS1 lead to a significant change in KIAA1432 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of KIAA1432. Does perturbing PTDSS1 lead to a significant change in KIAA1432 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of ANKRD11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of ANKRD11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of MS4A6E. Does this perturbation cause a significant change in MS4A6E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of MS4A6E. Does this perturbation cause a significant change in MS4A6E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of GCKR. Does this perturbation cause a significant change in GCKR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of GCKR. Does this perturbation cause a significant change in GCKR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
10,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of P4HA2 is measured. Does this perturbation cause a significant change in P4HA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of P4HA2 is measured. Does this perturbation cause a significant change in P4HA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
258,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor LINC00657 expression. Decide whether this perturbation leads to a significant alteration in LINC00657 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor LINC00657 expression. Decide whether this perturbation leads to a significant alteration in LINC00657 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1953,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of AC012594.1. Does this perturbation cause a significant change in AC012594.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of AC012594.1. Does this perturbation cause a significant change in AC012594.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and IDH3A expression is quantified. Does this perturbation result in a significant change in IDH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and IDH3A expression is quantified. Does this perturbation result in a significant change in IDH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3823,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and OBSCN expression is observed. Does this perturbation lead to a significant difference in OBSCN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and OBSCN expression is observed. Does this perturbation lead to a significant difference in OBSCN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
360,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of DOCK11 is measured. Does this perturbation cause a significant change in DOCK11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of DOCK11 is measured. Does this perturbation cause a significant change in DOCK11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of SNHG10. Does this perturbation cause a significant change in SNHG10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of SNHG10. Does this perturbation cause a significant change in SNHG10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and SLC27A2 expression is quantified. Does this perturbation result in a significant change in SLC27A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and SLC27A2 expression is quantified. Does this perturbation result in a significant change in SLC27A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and EP300 expression is quantified. Does this perturbation result in a significant change in EP300 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and EP300 expression is quantified. Does this perturbation result in a significant change in EP300 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3630,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of SOBP is measured. Does this perturbation cause a significant change in SOBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of SOBP is measured. Does this perturbation cause a significant change in SOBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
583,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and MYH7B expression is observed. Does this perturbation lead to a significant difference in MYH7B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and MYH7B expression is observed. Does this perturbation lead to a significant difference in MYH7B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3248,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor SERPING1 expression. Decide whether this perturbation leads to a significant alteration in SERPING1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor SERPING1 expression. Decide whether this perturbation leads to a significant alteration in SERPING1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of SMCO1. Does perturbing PPWD1 lead to a significant change in SMCO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of SMCO1. Does perturbing PPWD1 lead to a significant change in SMCO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in SPINK5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in SPINK5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2760,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of CDK13 is measured. Does this perturbation cause a significant change in CDK13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of CDK13 is measured. Does this perturbation cause a significant change in CDK13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and GS1-166A23.1 expression is measured. Determine whether GS1-166A23.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and GS1-166A23.1 expression is measured. Determine whether GS1-166A23.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of IL13RA1. Does perturbing HSPA9 lead to a significant change in IL13RA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of IL13RA1. Does perturbing HSPA9 lead to a significant change in IL13RA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5030,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of CELF6 is measured. Does this perturbation cause a significant change in CELF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of CELF6 is measured. Does this perturbation cause a significant change in CELF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and KLF6 expression is measured. Determine whether KLF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and KLF6 expression is measured. Determine whether KLF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in ATP5EP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in ATP5EP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of TAGLN is measured. Determine whether TAGLN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of TAGLN is measured. Determine whether TAGLN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of TKTL1. Does perturbing BHLHE40 lead to a significant change in TKTL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of TKTL1. Does perturbing BHLHE40 lead to a significant change in TKTL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and AP000688.8 expression is measured. Determine whether AP000688.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and AP000688.8 expression is measured. Determine whether AP000688.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in RP11-212I21.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in RP11-212I21.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of RNF8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of RNF8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in CLDN11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in CLDN11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and USP34 expression is measured. Determine whether USP34 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and USP34 expression is measured. Determine whether USP34 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in OR2T6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in OR2T6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4070,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of RP1-274L7.1 is measured. Does this perturbation cause a significant change in RP1-274L7.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of RP1-274L7.1 is measured. Does this perturbation cause a significant change in RP1-274L7.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5128,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor CDT1 expression. Decide whether this perturbation leads to a significant alteration in CDT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor CDT1 expression. Decide whether this perturbation leads to a significant alteration in CDT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in STK17B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in STK17B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and ATP2A3 expression is measured. Determine whether ATP2A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and ATP2A3 expression is measured. Determine whether ATP2A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and GLG1 expression is quantified. Does this perturbation result in a significant change in GLG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and GLG1 expression is quantified. Does this perturbation result in a significant change in GLG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4258,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor PAK1IP1 expression. Decide whether this perturbation leads to a significant alteration in PAK1IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor PAK1IP1 expression. Decide whether this perturbation leads to a significant alteration in PAK1IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and AC104532.4 expression is measured. Determine whether AC104532.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and AC104532.4 expression is measured. Determine whether AC104532.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and NAV2 expression is measured. Determine whether NAV2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and NAV2 expression is measured. Determine whether NAV2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of RP11-838N2.4. Does perturbing EIF2B2 lead to a significant change in RP11-838N2.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of RP11-838N2.4. Does perturbing EIF2B2 lead to a significant change in RP11-838N2.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of SNHG7. Does this perturbation cause a significant change in SNHG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of SNHG7. Does this perturbation cause a significant change in SNHG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of RILPL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of RILPL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of SEC23IP is measured. Determine whether SEC23IP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of SEC23IP is measured. Determine whether SEC23IP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2690,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of CD83 is measured. Does this perturbation cause a significant change in CD83 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of CD83 is measured. Does this perturbation cause a significant change in CD83 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4273,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and IDS expression is observed. Does this perturbation lead to a significant difference in IDS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and IDS expression is observed. Does this perturbation lead to a significant difference in IDS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1918,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor CTD-2587M2.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2587M2.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor CTD-2587M2.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2587M2.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of SERPINH1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of SERPINH1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of NRIP1. Does this perturbation cause a significant change in NRIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of NRIP1. Does this perturbation cause a significant change in NRIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in BAMBI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in BAMBI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of RP11-789C1.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of RP11-789C1.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of CENPC. Does this perturbation cause a significant change in CENPC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of CENPC. Does this perturbation cause a significant change in CENPC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in DNMBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in DNMBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and ZNF280B expression is quantified. Does this perturbation result in a significant change in ZNF280B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and ZNF280B expression is quantified. Does this perturbation result in a significant change in ZNF280B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of LINC00657 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of LINC00657 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of WHSC1. Does this perturbation cause a significant change in WHSC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of WHSC1. Does this perturbation cause a significant change in WHSC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of HM13. Does this perturbation cause a significant change in HM13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of HM13. Does this perturbation cause a significant change in HM13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and AC079466.1 expression is quantified. Does this perturbation result in a significant change in AC079466.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and AC079466.1 expression is quantified. Does this perturbation result in a significant change in AC079466.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2593,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and RP11-471M2.3 expression is observed. Does this perturbation lead to a significant difference in RP11-471M2.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and RP11-471M2.3 expression is observed. Does this perturbation lead to a significant difference in RP11-471M2.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of VPS41. Does this perturbation cause a significant change in VPS41 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of VPS41. Does this perturbation cause a significant change in VPS41 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and RPL39 expression is quantified. Does this perturbation result in a significant change in RPL39 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and RPL39 expression is quantified. Does this perturbation result in a significant change in RPL39 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1718,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor EPB42 expression. Decide whether this perturbation leads to a significant alteration in EPB42 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor EPB42 expression. Decide whether this perturbation leads to a significant alteration in EPB42 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of NAV2. Does this perturbation cause a significant change in NAV2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of NAV2. Does this perturbation cause a significant change in NAV2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and CCRL2 expression is quantified. Does this perturbation result in a significant change in CCRL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and CCRL2 expression is quantified. Does this perturbation result in a significant change in CCRL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1060,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of KHDC1L is measured. Does this perturbation cause a significant change in KHDC1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of KHDC1L is measured. Does this perturbation cause a significant change in KHDC1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and TIPARP expression is measured. Determine whether TIPARP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and TIPARP expression is measured. Determine whether TIPARP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3580,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of RP3-465N24.6 is measured. Does this perturbation cause a significant change in RP3-465N24.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of RP3-465N24.6 is measured. Does this perturbation cause a significant change in RP3-465N24.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of SLFNL1. Does perturbing SRPR lead to a significant change in SLFNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of SLFNL1. Does perturbing SRPR lead to a significant change in SLFNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1740,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of RPL39 is measured. Does this perturbation cause a significant change in RPL39 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of RPL39 is measured. Does this perturbation cause a significant change in RPL39 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of HIST1H2AC. Does perturbing EIF2B2 lead to a significant change in HIST1H2AC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of HIST1H2AC. Does perturbing EIF2B2 lead to a significant change in HIST1H2AC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in HIST1H2AM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in HIST1H2AM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3773,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and ZNF341 expression is observed. Does this perturbation lead to a significant difference in ZNF341 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and ZNF341 expression is observed. Does this perturbation lead to a significant difference in ZNF341 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4933,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and ATXN7L3B expression is observed. Does this perturbation lead to a significant difference in ATXN7L3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and ATXN7L3B expression is observed. Does this perturbation lead to a significant difference in ATXN7L3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and ANKRD33 expression is quantified. Does this perturbation result in a significant change in ANKRD33 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and ANKRD33 expression is quantified. Does this perturbation result in a significant change in ANKRD33 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of ZNF789 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of ZNF789 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and CTD-2267D19.3 expression is quantified. Does this perturbation result in a significant change in CTD-2267D19.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and CTD-2267D19.3 expression is quantified. Does this perturbation result in a significant change in CTD-2267D19.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of C19orf59. Does perturbing HSPA9 lead to a significant change in C19orf59 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of C19orf59. Does perturbing HSPA9 lead to a significant change in C19orf59 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3820,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of OBSCN is measured. Does this perturbation cause a significant change in OBSCN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of OBSCN is measured. Does this perturbation cause a significant change in OBSCN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of RP11-138C9.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of RP11-138C9.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of ITGB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of ITGB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of CTD-2521M24.9. Does this perturbation cause a significant change in CTD-2521M24.9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of CTD-2521M24.9. Does this perturbation cause a significant change in CTD-2521M24.9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of RP11-360L9.8. Does perturbing AARS lead to a significant change in RP11-360L9.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of RP11-360L9.8. Does perturbing AARS lead to a significant change in RP11-360L9.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in CDKN2C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in CDKN2C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of TLN1. Does this perturbation cause a significant change in TLN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of TLN1. Does this perturbation cause a significant change in TLN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2058,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor EP300 expression. Decide whether this perturbation leads to a significant alteration in EP300 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor EP300 expression. Decide whether this perturbation leads to a significant alteration in EP300 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and LRIF1 expression is measured. Determine whether LRIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and LRIF1 expression is measured. Determine whether LRIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and IDH3A expression is measured. Determine whether IDH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and IDH3A expression is measured. Determine whether IDH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5068,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor PCF11 expression. Decide whether this perturbation leads to a significant alteration in PCF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor PCF11 expression. Decide whether this perturbation leads to a significant alteration in PCF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of HIST1H2AC is measured. Determine whether HIST1H2AC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of HIST1H2AC is measured. Determine whether HIST1H2AC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of SPEN. Does this perturbation cause a significant change in SPEN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of SPEN. Does this perturbation cause a significant change in SPEN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1538,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor C12orf44 expression. Decide whether this perturbation leads to a significant alteration in C12orf44 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor C12orf44 expression. Decide whether this perturbation leads to a significant alteration in C12orf44 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1608,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor ATP6V1B2 expression. Decide whether this perturbation leads to a significant alteration in ATP6V1B2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor ATP6V1B2 expression. Decide whether this perturbation leads to a significant alteration in ATP6V1B2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of RSL24D1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of RSL24D1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4533,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and RP11-304M2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-304M2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and RP11-304M2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-304M2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of DOCK8. Does perturbing PDIA6 lead to a significant change in DOCK8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of DOCK8. Does perturbing PDIA6 lead to a significant change in DOCK8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2103,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and PTAR1 expression is observed. Does this perturbation lead to a significant difference in PTAR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and PTAR1 expression is observed. Does this perturbation lead to a significant difference in PTAR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of RP11-360L9.8. Does this perturbation cause a significant change in RP11-360L9.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of RP11-360L9.8. Does this perturbation cause a significant change in RP11-360L9.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of LBX1 is measured. Determine whether LBX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of LBX1 is measured. Determine whether LBX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in BOLA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in BOLA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and LTB expression is measured. Determine whether LTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and LTB expression is measured. Determine whether LTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in TUBA1C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in TUBA1C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3923,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and PPM1N expression is observed. Does this perturbation lead to a significant difference in PPM1N expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and PPM1N expression is observed. Does this perturbation lead to a significant difference in PPM1N expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of HLTF. Does perturbing GBF1 lead to a significant change in HLTF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of HLTF. Does perturbing GBF1 lead to a significant change in HLTF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and MORC2-AS1 expression is quantified. Does this perturbation result in a significant change in MORC2-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and MORC2-AS1 expression is quantified. Does this perturbation result in a significant change in MORC2-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of PHF21A. Does this perturbation cause a significant change in PHF21A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of PHF21A. Does this perturbation cause a significant change in PHF21A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2293,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and KLF6 expression is observed. Does this perturbation lead to a significant difference in KLF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and KLF6 expression is observed. Does this perturbation lead to a significant difference in KLF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of PDRG1. Does perturbing COPB1 lead to a significant change in PDRG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of PDRG1. Does perturbing COPB1 lead to a significant change in PDRG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of ZNF678. Does perturbing STT3A lead to a significant change in ZNF678 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of ZNF678. Does perturbing STT3A lead to a significant change in ZNF678 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3340,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of SIGLEC6 is measured. Does this perturbation cause a significant change in SIGLEC6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of SIGLEC6 is measured. Does this perturbation cause a significant change in SIGLEC6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and DNMBP expression is quantified. Does this perturbation result in a significant change in DNMBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and DNMBP expression is quantified. Does this perturbation result in a significant change in DNMBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in ERP29 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in ERP29 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of RBM12B-AS1. Does this perturbation cause a significant change in RBM12B-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of RBM12B-AS1. Does this perturbation cause a significant change in RBM12B-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of UQCRB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of UQCRB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and FCGRT expression is quantified. Does this perturbation result in a significant change in FCGRT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and FCGRT expression is quantified. Does this perturbation result in a significant change in FCGRT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3558,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor CCRL2 expression. Decide whether this perturbation leads to a significant alteration in CCRL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor CCRL2 expression. Decide whether this perturbation leads to a significant alteration in CCRL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
353,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and IL18R1 expression is observed. Does this perturbation lead to a significant difference in IL18R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and IL18R1 expression is observed. Does this perturbation lead to a significant difference in IL18R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in SKIL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in SKIL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of RP11-227G15.8 is measured. Determine whether RP11-227G15.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of RP11-227G15.8 is measured. Determine whether RP11-227G15.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of APOBEC3D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of APOBEC3D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1493,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and RP11-24F11.2 expression is observed. Does this perturbation lead to a significant difference in RP11-24F11.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and RP11-24F11.2 expression is observed. Does this perturbation lead to a significant difference in RP11-24F11.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of VIM-AS1. Does perturbing SYVN1 lead to a significant change in VIM-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of VIM-AS1. Does perturbing SYVN1 lead to a significant change in VIM-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
90,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RP11-141B14.1 is measured. Does this perturbation cause a significant change in RP11-141B14.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RP11-141B14.1 is measured. Does this perturbation cause a significant change in RP11-141B14.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in RIMS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in RIMS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
608,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor PBDC1 expression. Decide whether this perturbation leads to a significant alteration in PBDC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor PBDC1 expression. Decide whether this perturbation leads to a significant alteration in PBDC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2828,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor PSMC1 expression. Decide whether this perturbation leads to a significant alteration in PSMC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor PSMC1 expression. Decide whether this perturbation leads to a significant alteration in PSMC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and EP300 expression is quantified. Does this perturbation result in a significant change in EP300 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and EP300 expression is quantified. Does this perturbation result in a significant change in EP300 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of RBM12B-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of RBM12B-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2733,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of ADAMTS10. Does perturbing IARS2 lead to a significant change in ADAMTS10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of ADAMTS10. Does perturbing IARS2 lead to a significant change in ADAMTS10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in ANKRD11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in ANKRD11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4810,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of MBNL1 is measured. Does this perturbation cause a significant change in MBNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of MBNL1 is measured. Does this perturbation cause a significant change in MBNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3313,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and EGLN3 expression is observed. Does this perturbation lead to a significant difference in EGLN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and EGLN3 expression is observed. Does this perturbation lead to a significant difference in EGLN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of SETX is measured. Determine whether SETX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of SETX is measured. Determine whether SETX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of S100A11 is measured. Determine whether S100A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of S100A11 is measured. Determine whether S100A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
488,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor VIM-AS1 expression. Decide whether this perturbation leads to a significant alteration in VIM-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor VIM-AS1 expression. Decide whether this perturbation leads to a significant alteration in VIM-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2458,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor CTNNB1 expression. Decide whether this perturbation leads to a significant alteration in CTNNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor CTNNB1 expression. Decide whether this perturbation leads to a significant alteration in CTNNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and GALNT7 expression is measured. Determine whether GALNT7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and GALNT7 expression is measured. Determine whether GALNT7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2650,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of IFNGR1 is measured. Does this perturbation cause a significant change in IFNGR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of IFNGR1 is measured. Does this perturbation cause a significant change in IFNGR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RP11-65L19.4 expression is measured. Determine whether RP11-65L19.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RP11-65L19.4 expression is measured. Determine whether RP11-65L19.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in PLB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in PLB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and ARHGAP30 expression is measured. Determine whether ARHGAP30 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and ARHGAP30 expression is measured. Determine whether ARHGAP30 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of CD9. Does this perturbation cause a significant change in CD9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of CD9. Does this perturbation cause a significant change in CD9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in VAMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in VAMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of AFF1. Does this perturbation cause a significant change in AFF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of AFF1. Does this perturbation cause a significant change in AFF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2270,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of PSORS1C1 is measured. Does this perturbation cause a significant change in PSORS1C1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of PSORS1C1 is measured. Does this perturbation cause a significant change in PSORS1C1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3533,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and FCGRT expression is observed. Does this perturbation lead to a significant difference in FCGRT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and FCGRT expression is observed. Does this perturbation lead to a significant difference in FCGRT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and ACSM3 expression is measured. Determine whether ACSM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and ACSM3 expression is measured. Determine whether ACSM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of PTAR1. Does perturbing SLC39A7 lead to a significant change in PTAR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of PTAR1. Does perturbing SLC39A7 lead to a significant change in PTAR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and GNPTG expression is measured. Determine whether GNPTG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and GNPTG expression is measured. Determine whether GNPTG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of ZEB2. Does perturbing IDH3A lead to a significant change in ZEB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of ZEB2. Does perturbing IDH3A lead to a significant change in ZEB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and PBDC1 expression is measured. Determine whether PBDC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and PBDC1 expression is measured. Determine whether PBDC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ZXDA expression is measured. Determine whether ZXDA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ZXDA expression is measured. Determine whether ZXDA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and PDK2 expression is measured. Determine whether PDK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and PDK2 expression is measured. Determine whether PDK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in CHST12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in CHST12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of PBDC1 is measured. Determine whether PBDC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of PBDC1 is measured. Determine whether PBDC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ARHGAP6 is measured. Determine whether ARHGAP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ARHGAP6 is measured. Determine whether ARHGAP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in RTN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in RTN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and HLA-AS1 expression is quantified. Does this perturbation result in a significant change in HLA-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and HLA-AS1 expression is quantified. Does this perturbation result in a significant change in HLA-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and DDIT4 expression is quantified. Does this perturbation result in a significant change in DDIT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and DDIT4 expression is quantified. Does this perturbation result in a significant change in DDIT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3908,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ARHGAP6 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ARHGAP6 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1013,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and KCNE3 expression is observed. Does this perturbation lead to a significant difference in KCNE3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and KCNE3 expression is observed. Does this perturbation lead to a significant difference in KCNE3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
118,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RP11-65L19.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-65L19.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RP11-65L19.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-65L19.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of PDRG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of PDRG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and UHRF1BP1L expression is quantified. Does this perturbation result in a significant change in UHRF1BP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and UHRF1BP1L expression is quantified. Does this perturbation result in a significant change in UHRF1BP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
683,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and ARSA expression is observed. Does this perturbation lead to a significant difference in ARSA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and ARSA expression is observed. Does this perturbation lead to a significant difference in ARSA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and IL18R1 expression is quantified. Does this perturbation result in a significant change in IL18R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and IL18R1 expression is quantified. Does this perturbation result in a significant change in IL18R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of UBE2V1 is measured. Determine whether UBE2V1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of UBE2V1 is measured. Determine whether UBE2V1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of SLC37A1 is measured. Determine whether SLC37A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of SLC37A1 is measured. Determine whether SLC37A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of EXOC3L2. Does perturbing PSMD4 lead to a significant change in EXOC3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of EXOC3L2. Does perturbing PSMD4 lead to a significant change in EXOC3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and EIF3A expression is measured. Determine whether EIF3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and EIF3A expression is measured. Determine whether EIF3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of CDCA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of CDCA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and RP11-16E12.1 expression is measured. Determine whether RP11-16E12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and RP11-16E12.1 expression is measured. Determine whether RP11-16E12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of PSORS1C1. Does perturbing NEDD8 lead to a significant change in PSORS1C1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of PSORS1C1. Does perturbing NEDD8 lead to a significant change in PSORS1C1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of H1FX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of H1FX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of FAM212A. Does this perturbation cause a significant change in FAM212A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of FAM212A. Does this perturbation cause a significant change in FAM212A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3818,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor RP11-445H22.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-445H22.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor RP11-445H22.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-445H22.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of BRWD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of BRWD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of STK17B is measured. Determine whether STK17B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of STK17B is measured. Determine whether STK17B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4313,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and MED13 expression is observed. Does this perturbation lead to a significant difference in MED13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and MED13 expression is observed. Does this perturbation lead to a significant difference in MED13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1348,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor NSD1 expression. Decide whether this perturbation leads to a significant alteration in NSD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor NSD1 expression. Decide whether this perturbation leads to a significant alteration in NSD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and ATP6V1B2 expression is measured. Determine whether ATP6V1B2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and ATP6V1B2 expression is measured. Determine whether ATP6V1B2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of WARS. Does this perturbation cause a significant change in WARS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of WARS. Does this perturbation cause a significant change in WARS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
308,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor RP11-423O2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-423O2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor RP11-423O2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-423O2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of AC015987.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of AC015987.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and IFNGR1 expression is measured. Determine whether IFNGR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and IFNGR1 expression is measured. Determine whether IFNGR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in TOPBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in TOPBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of LDLR. Does this perturbation cause a significant change in LDLR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of LDLR. Does this perturbation cause a significant change in LDLR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in HP1BP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in HP1BP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
35,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in CASP4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in CASP4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in IL8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in IL8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3400,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of C3AR1 is measured. Does this perturbation cause a significant change in C3AR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of C3AR1 is measured. Does this perturbation cause a significant change in C3AR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of PCK2. Does this perturbation cause a significant change in PCK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of PCK2. Does this perturbation cause a significant change in PCK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of SLC37A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of SLC37A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and DDX6 expression is quantified. Does this perturbation result in a significant change in DDX6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and DDX6 expression is quantified. Does this perturbation result in a significant change in DDX6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
830,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of RP11-138C9.1 is measured. Does this perturbation cause a significant change in RP11-138C9.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of RP11-138C9.1 is measured. Does this perturbation cause a significant change in RP11-138C9.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4248,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor LINC01031 expression. Decide whether this perturbation leads to a significant alteration in LINC01031 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor LINC01031 expression. Decide whether this perturbation leads to a significant alteration in LINC01031 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of KIAA1731 is measured. Determine whether KIAA1731 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of KIAA1731 is measured. Determine whether KIAA1731 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and ZCCHC11 expression is quantified. Does this perturbation result in a significant change in ZCCHC11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and ZCCHC11 expression is quantified. Does this perturbation result in a significant change in ZCCHC11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2998,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor CTD-2521M24.9 expression. Decide whether this perturbation leads to a significant alteration in CTD-2521M24.9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor CTD-2521M24.9 expression. Decide whether this perturbation leads to a significant alteration in CTD-2521M24.9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4660,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of LINC01137 is measured. Does this perturbation cause a significant change in LINC01137 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of LINC01137 is measured. Does this perturbation cause a significant change in LINC01137 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
448,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor NCKAP1L expression. Decide whether this perturbation leads to a significant alteration in NCKAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor NCKAP1L expression. Decide whether this perturbation leads to a significant alteration in NCKAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of RP11-360L9.8. Does this perturbation cause a significant change in RP11-360L9.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of RP11-360L9.8. Does this perturbation cause a significant change in RP11-360L9.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of POLR2J3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of POLR2J3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and OBSCN expression is measured. Determine whether OBSCN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and OBSCN expression is measured. Determine whether OBSCN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of SP100. Does this perturbation cause a significant change in SP100 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of SP100. Does this perturbation cause a significant change in SP100 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
453,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and SLFNL1 expression is observed. Does this perturbation lead to a significant difference in SLFNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and SLFNL1 expression is observed. Does this perturbation lead to a significant difference in SLFNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of ACE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of ACE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3238,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor RP11-16E12.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-16E12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor RP11-16E12.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-16E12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
71,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of CEBPG. Does perturbing ZNF326 lead to a significant change in CEBPG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of CEBPG. Does perturbing ZNF326 lead to a significant change in CEBPG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ROBO1. Does this perturbation cause a significant change in ROBO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ROBO1. Does this perturbation cause a significant change in ROBO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of RP11-24F11.2. Does perturbing MRGBP lead to a significant change in RP11-24F11.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of RP11-24F11.2. Does perturbing MRGBP lead to a significant change in RP11-24F11.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of CTD-2020K17.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of CTD-2020K17.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of ATP2A3 is measured. Determine whether ATP2A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of ATP2A3 is measured. Determine whether ATP2A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4153,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and PDRG1 expression is observed. Does this perturbation lead to a significant difference in PDRG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and PDRG1 expression is observed. Does this perturbation lead to a significant difference in PDRG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and ESCO1 expression is quantified. Does this perturbation result in a significant change in ESCO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and ESCO1 expression is quantified. Does this perturbation result in a significant change in ESCO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2540,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of ZP3 is measured. Does this perturbation cause a significant change in ZP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of ZP3 is measured. Does this perturbation cause a significant change in ZP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of LTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of LTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1668,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor RP11-247A12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-247A12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor RP11-247A12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-247A12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of SPAST. Does perturbing SEC61B lead to a significant change in SPAST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of SPAST. Does perturbing SEC61B lead to a significant change in SPAST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3180,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of RNF8 is measured. Does this perturbation cause a significant change in RNF8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of RNF8 is measured. Does this perturbation cause a significant change in RNF8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4663,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and LINC01137 expression is observed. Does this perturbation lead to a significant difference in LINC01137 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and LINC01137 expression is observed. Does this perturbation lead to a significant difference in LINC01137 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and PTAR1 expression is measured. Determine whether PTAR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and PTAR1 expression is measured. Determine whether PTAR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1693,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of MBNL1. Does perturbing XRN1 lead to a significant change in MBNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of MBNL1. Does perturbing XRN1 lead to a significant change in MBNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of P4HB. Does this perturbation cause a significant change in P4HB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of P4HB. Does this perturbation cause a significant change in P4HB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of TLK2. Does this perturbation cause a significant change in TLK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of TLK2. Does this perturbation cause a significant change in TLK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2450,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of CTNNB1 is measured. Does this perturbation cause a significant change in CTNNB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of CTNNB1 is measured. Does this perturbation cause a significant change in CTNNB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and RP11-254F7.4 expression is quantified. Does this perturbation result in a significant change in RP11-254F7.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and RP11-254F7.4 expression is quantified. Does this perturbation result in a significant change in RP11-254F7.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and SLC25A35 expression is measured. Determine whether SLC25A35 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and SLC25A35 expression is measured. Determine whether SLC25A35 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in RP11-363D14.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in RP11-363D14.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of ANKRD33. Does perturbing COPB1 lead to a significant change in ANKRD33 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of ANKRD33. Does perturbing COPB1 lead to a significant change in ANKRD33 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1888,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor SNHG10 expression. Decide whether this perturbation leads to a significant alteration in SNHG10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor SNHG10 expression. Decide whether this perturbation leads to a significant alteration in SNHG10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of UBE3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of UBE3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of SLC27A2. Does perturbing TIMM44 lead to a significant change in SLC27A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of SLC27A2. Does perturbing TIMM44 lead to a significant change in SLC27A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of SETD5-AS1 is measured. Determine whether SETD5-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of SETD5-AS1 is measured. Determine whether SETD5-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in SLC26A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in SLC26A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of LAMP2. Does this perturbation cause a significant change in LAMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of LAMP2. Does this perturbation cause a significant change in LAMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of TSC22D4 is measured. Determine whether TSC22D4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of TSC22D4 is measured. Determine whether TSC22D4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4913,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and CMTM6 expression is observed. Does this perturbation lead to a significant difference in CMTM6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and CMTM6 expression is observed. Does this perturbation lead to a significant difference in CMTM6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of SMIM14. Does this perturbation cause a significant change in SMIM14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of SMIM14. Does this perturbation cause a significant change in SMIM14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2318,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor ANKLE2 expression. Decide whether this perturbation leads to a significant alteration in ANKLE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor ANKLE2 expression. Decide whether this perturbation leads to a significant alteration in ANKLE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
140,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of RDH10 is measured. Does this perturbation cause a significant change in RDH10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of RDH10 is measured. Does this perturbation cause a significant change in RDH10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of HIST1H2AC. Does this perturbation cause a significant change in HIST1H2AC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of HIST1H2AC. Does this perturbation cause a significant change in HIST1H2AC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of SNHG10. Does this perturbation cause a significant change in SNHG10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of SNHG10. Does this perturbation cause a significant change in SNHG10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1820,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of DDIT4 is measured. Does this perturbation cause a significant change in DDIT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of DDIT4 is measured. Does this perturbation cause a significant change in DDIT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of RSAD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of RSAD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3730,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of PITPNB is measured. Does this perturbation cause a significant change in PITPNB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of PITPNB is measured. Does this perturbation cause a significant change in PITPNB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PSMD14 expression is measured. Determine whether PSMD14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PSMD14 expression is measured. Determine whether PSMD14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5120,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of CDT1 is measured. Does this perturbation cause a significant change in CDT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of CDT1 is measured. Does this perturbation cause a significant change in CDT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and TLK2 expression is quantified. Does this perturbation result in a significant change in TLK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and TLK2 expression is quantified. Does this perturbation result in a significant change in TLK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in MED13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in MED13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of ARHGAP11A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of ARHGAP11A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1153,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and SLC37A1 expression is observed. Does this perturbation lead to a significant difference in SLC37A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and SLC37A1 expression is observed. Does this perturbation lead to a significant difference in SLC37A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
590,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of PPP1R16B is measured. Does this perturbation cause a significant change in PPP1R16B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of PPP1R16B is measured. Does this perturbation cause a significant change in PPP1R16B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in LINC01031 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in LINC01031 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and LTN1 expression is measured. Determine whether LTN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and LTN1 expression is measured. Determine whether LTN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of RILPL2. Does this perturbation cause a significant change in RILPL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of RILPL2. Does this perturbation cause a significant change in RILPL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
810,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of DNTTIP2 is measured. Does this perturbation cause a significant change in DNTTIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of DNTTIP2 is measured. Does this perturbation cause a significant change in DNTTIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of POU2F2. Does perturbing HARS lead to a significant change in POU2F2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of POU2F2. Does perturbing HARS lead to a significant change in POU2F2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in UFD1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in UFD1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3133,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and LTN1 expression is observed. Does this perturbation lead to a significant difference in LTN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and LTN1 expression is observed. Does this perturbation lead to a significant difference in LTN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and CTD-2020K17.1 expression is quantified. Does this perturbation result in a significant change in CTD-2020K17.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and CTD-2020K17.1 expression is quantified. Does this perturbation result in a significant change in CTD-2020K17.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of SP100. Does perturbing UFL1 lead to a significant change in SP100 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of SP100. Does perturbing UFL1 lead to a significant change in SP100 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of MANF is measured. Determine whether MANF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of MANF is measured. Determine whether MANF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
27,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of PHF21A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of PHF21A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of CENPC. Does perturbing PPWD1 lead to a significant change in CENPC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of CENPC. Does perturbing PPWD1 lead to a significant change in CENPC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of MANF. Does this perturbation cause a significant change in MANF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of MANF. Does this perturbation cause a significant change in MANF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of HIST1H1E. Does this perturbation cause a significant change in HIST1H1E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of HIST1H1E. Does this perturbation cause a significant change in HIST1H1E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in KLF3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in KLF3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and ESCO1 expression is measured. Determine whether ESCO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and ESCO1 expression is measured. Determine whether ESCO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2978,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor HPCAL1 expression. Decide whether this perturbation leads to a significant alteration in HPCAL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor HPCAL1 expression. Decide whether this perturbation leads to a significant alteration in HPCAL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and MLEC expression is quantified. Does this perturbation result in a significant change in MLEC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and MLEC expression is quantified. Does this perturbation result in a significant change in MLEC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RGS20. Does perturbing MARS lead to a significant change in RGS20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RGS20. Does perturbing MARS lead to a significant change in RGS20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in HMGCS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in HMGCS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and H1FX expression is measured. Determine whether H1FX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and H1FX expression is measured. Determine whether H1FX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of C6orf120. Does this perturbation cause a significant change in C6orf120 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of C6orf120. Does this perturbation cause a significant change in C6orf120 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and CHST12 expression is measured. Determine whether CHST12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and CHST12 expression is measured. Determine whether CHST12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of ZCCHC11. Does perturbing P4HB lead to a significant change in ZCCHC11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of ZCCHC11. Does perturbing P4HB lead to a significant change in ZCCHC11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
283,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and CDRT4 expression is observed. Does this perturbation lead to a significant difference in CDRT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and CDRT4 expression is observed. Does this perturbation lead to a significant difference in CDRT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
76,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of CEBPG is measured. Determine whether CEBPG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of CEBPG is measured. Determine whether CEBPG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and RP11-390B4.5 expression is measured. Determine whether RP11-390B4.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and RP11-390B4.5 expression is measured. Determine whether RP11-390B4.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2678,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor CTSV expression. Decide whether this perturbation leads to a significant alteration in CTSV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor CTSV expression. Decide whether this perturbation leads to a significant alteration in CTSV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of RP11-242O24.5. Does this perturbation cause a significant change in RP11-242O24.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of RP11-242O24.5. Does this perturbation cause a significant change in RP11-242O24.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and NRIP1 expression is measured. Determine whether NRIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and NRIP1 expression is measured. Determine whether NRIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and QSER1 expression is quantified. Does this perturbation result in a significant change in QSER1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and QSER1 expression is quantified. Does this perturbation result in a significant change in QSER1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and PLA2G15 expression is quantified. Does this perturbation result in a significant change in PLA2G15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and PLA2G15 expression is quantified. Does this perturbation result in a significant change in PLA2G15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and TRAPPC10 expression is measured. Determine whether TRAPPC10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and TRAPPC10 expression is measured. Determine whether TRAPPC10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4400,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of RSAD2 is measured. Does this perturbation cause a significant change in RSAD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of RSAD2 is measured. Does this perturbation cause a significant change in RSAD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of FOXO6 is measured. Determine whether FOXO6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of FOXO6 is measured. Determine whether FOXO6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of KDM1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of KDM1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of RP11-38P22.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of RP11-38P22.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3478,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor BACH2 expression. Decide whether this perturbation leads to a significant alteration in BACH2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor BACH2 expression. Decide whether this perturbation leads to a significant alteration in BACH2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and VIMP expression is quantified. Does this perturbation result in a significant change in VIMP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and VIMP expression is quantified. Does this perturbation result in a significant change in VIMP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2400,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of P4HA2 is measured. Does this perturbation cause a significant change in P4HA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of P4HA2 is measured. Does this perturbation cause a significant change in P4HA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of RP11-360L9.8 is measured. Determine whether RP11-360L9.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of RP11-360L9.8 is measured. Determine whether RP11-360L9.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in TTC32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in TTC32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of RNF139-AS1 is measured. Determine whether RNF139-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of RNF139-AS1 is measured. Determine whether RNF139-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of CDKN2C is measured. Determine whether CDKN2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of CDKN2C is measured. Determine whether CDKN2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
313,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2660,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of ASPM is measured. Does this perturbation cause a significant change in ASPM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of ASPM is measured. Does this perturbation cause a significant change in ASPM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1423,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and RP11-61E11.1 expression is observed. Does this perturbation lead to a significant difference in RP11-61E11.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and RP11-61E11.1 expression is observed. Does this perturbation lead to a significant difference in RP11-61E11.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of AC005540.3 is measured. Determine whether AC005540.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of AC005540.3 is measured. Determine whether AC005540.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2698,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor CD83 expression. Decide whether this perturbation leads to a significant alteration in CD83 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor CD83 expression. Decide whether this perturbation leads to a significant alteration in CD83 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of DNTTIP2. Does this perturbation cause a significant change in DNTTIP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of DNTTIP2. Does this perturbation cause a significant change in DNTTIP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in RP11-304M2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in RP11-304M2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4850,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of STK17B is measured. Does this perturbation cause a significant change in STK17B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of STK17B is measured. Does this perturbation cause a significant change in STK17B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3768,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor RNF19A expression. Decide whether this perturbation leads to a significant alteration in RNF19A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor RNF19A expression. Decide whether this perturbation leads to a significant alteration in RNF19A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of CTD-2267D19.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of CTD-2267D19.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in PLA2G15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in PLA2G15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
680,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of ARSA is measured. Does this perturbation cause a significant change in ARSA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of ARSA is measured. Does this perturbation cause a significant change in ARSA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of KCTD19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of KCTD19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and TGOLN2 expression is quantified. Does this perturbation result in a significant change in TGOLN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and TGOLN2 expression is quantified. Does this perturbation result in a significant change in TGOLN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of RP11-16E12.1 is measured. Determine whether RP11-16E12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of RP11-16E12.1 is measured. Determine whether RP11-16E12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of PTBP3. Does this perturbation cause a significant change in PTBP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of PTBP3. Does this perturbation cause a significant change in PTBP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of TSNAXIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of TSNAXIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of STARD9. Does this perturbation cause a significant change in STARD9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of STARD9. Does this perturbation cause a significant change in STARD9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of MLEC. Does this perturbation cause a significant change in MLEC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of MLEC. Does this perturbation cause a significant change in MLEC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
780,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of WHAMM is measured. Does this perturbation cause a significant change in WHAMM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of WHAMM is measured. Does this perturbation cause a significant change in WHAMM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and DNASE2 expression is quantified. Does this perturbation result in a significant change in DNASE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and DNASE2 expression is quantified. Does this perturbation result in a significant change in DNASE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and C3AR1 expression is quantified. Does this perturbation result in a significant change in C3AR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and C3AR1 expression is quantified. Does this perturbation result in a significant change in C3AR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and CTD-2001C12.1 expression is quantified. Does this perturbation result in a significant change in CTD-2001C12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and CTD-2001C12.1 expression is quantified. Does this perturbation result in a significant change in CTD-2001C12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
943,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and RP11-789C1.1 expression is observed. Does this perturbation lead to a significant difference in RP11-789C1.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and RP11-789C1.1 expression is observed. Does this perturbation lead to a significant difference in RP11-789C1.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of DUSP21. Does this perturbation cause a significant change in DUSP21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of DUSP21. Does this perturbation cause a significant change in DUSP21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of BAMBI. Does this perturbation cause a significant change in BAMBI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of BAMBI. Does this perturbation cause a significant change in BAMBI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of ARHGDIB is measured. Determine whether ARHGDIB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of ARHGDIB is measured. Determine whether ARHGDIB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3880,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of RP11-573D15.2 is measured. Does this perturbation cause a significant change in RP11-573D15.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of RP11-573D15.2 is measured. Does this perturbation cause a significant change in RP11-573D15.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in NAV2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in NAV2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and RP11-138C9.1 expression is quantified. Does this perturbation result in a significant change in RP11-138C9.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and RP11-138C9.1 expression is quantified. Does this perturbation result in a significant change in RP11-138C9.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of SKIL is measured. Determine whether SKIL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of SKIL is measured. Determine whether SKIL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of PELO indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of PELO indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4778,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor HIST1H2BC expression. Decide whether this perturbation leads to a significant alteration in HIST1H2BC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor HIST1H2BC expression. Decide whether this perturbation leads to a significant alteration in HIST1H2BC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of PTGS1 is measured. Determine whether PTGS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of PTGS1 is measured. Determine whether PTGS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4750,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of CLDN11 is measured. Determine whether CLDN11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of CLDN11 is measured. Determine whether CLDN11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of USP37. Does perturbing SYVN1 lead to a significant change in USP37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of USP37. Does perturbing SYVN1 lead to a significant change in USP37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and TOPBP1 expression is quantified. Does this perturbation result in a significant change in TOPBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and TOPBP1 expression is quantified. Does this perturbation result in a significant change in TOPBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of ESCO1. Does perturbing AMIGO3 lead to a significant change in ESCO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of ESCO1. Does perturbing AMIGO3 lead to a significant change in ESCO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of PELO. Does perturbing SLC39A7 lead to a significant change in PELO expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of PELO. Does perturbing SLC39A7 lead to a significant change in PELO expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2863,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and PIK3IP1 expression is observed. Does this perturbation lead to a significant difference in PIK3IP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and PIK3IP1 expression is observed. Does this perturbation lead to a significant difference in PIK3IP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of DSC2. Does perturbing UFM1 lead to a significant change in DSC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of DSC2. Does perturbing UFM1 lead to a significant change in DSC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1923,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and AKAP11 expression is observed. Does this perturbation lead to a significant difference in AKAP11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and AKAP11 expression is observed. Does this perturbation lead to a significant difference in AKAP11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and WHAMM expression is quantified. Does this perturbation result in a significant change in WHAMM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and WHAMM expression is quantified. Does this perturbation result in a significant change in WHAMM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of PIK3IP1 is measured. Determine whether PIK3IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of PIK3IP1 is measured. Determine whether PIK3IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of HP1BP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of HP1BP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in S100A10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in S100A10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of ZNF292. Does perturbing SEL1L lead to a significant change in ZNF292 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of ZNF292. Does perturbing SEL1L lead to a significant change in ZNF292 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of RP11-360L9.8. Does perturbing HSD17B12 lead to a significant change in RP11-360L9.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of RP11-360L9.8. Does perturbing HSD17B12 lead to a significant change in RP11-360L9.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of SOBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of SOBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
57,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of C6orf48 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of C6orf48 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of GRN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of GRN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2480,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of HLTF is measured. Does this perturbation cause a significant change in HLTF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of HLTF is measured. Does this perturbation cause a significant change in HLTF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4713,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and TAP1 expression is observed. Does this perturbation lead to a significant difference in TAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and TAP1 expression is observed. Does this perturbation lead to a significant difference in TAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of DOK3. Does perturbing OST4 lead to a significant change in DOK3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of DOK3. Does perturbing OST4 lead to a significant change in DOK3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1283,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and ZNF280B expression is observed. Does this perturbation lead to a significant difference in ZNF280B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and ZNF280B expression is observed. Does this perturbation lead to a significant difference in ZNF280B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of RP11-381O7.3. Does perturbing SEL1L lead to a significant change in RP11-381O7.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of RP11-381O7.3. Does perturbing SEL1L lead to a significant change in RP11-381O7.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of PITPNB. Does this perturbation cause a significant change in PITPNB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of PITPNB. Does this perturbation cause a significant change in PITPNB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of ARSA. Does perturbing SLMO2 lead to a significant change in ARSA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of ARSA. Does perturbing SLMO2 lead to a significant change in ARSA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in GUSB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in GUSB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2588,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor KIF4A expression. Decide whether this perturbation leads to a significant alteration in KIF4A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor KIF4A expression. Decide whether this perturbation leads to a significant alteration in KIF4A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and NXF1 expression is measured. Determine whether NXF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and NXF1 expression is measured. Determine whether NXF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of USP34. Does this perturbation cause a significant change in USP34 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of USP34. Does this perturbation cause a significant change in USP34 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of TFPI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of TFPI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and HOTAIRM1 expression is measured. Determine whether HOTAIRM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and HOTAIRM1 expression is measured. Determine whether HOTAIRM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of HERC2. Does this perturbation cause a significant change in HERC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of HERC2. Does this perturbation cause a significant change in HERC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of TSC22D4. Does perturbing HSPA5 lead to a significant change in TSC22D4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of TSC22D4. Does perturbing HSPA5 lead to a significant change in TSC22D4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1950,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of SMCO1. Does this perturbation cause a significant change in SMCO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of SMCO1. Does this perturbation cause a significant change in SMCO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of HAGH. Does this perturbation cause a significant change in HAGH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of HAGH. Does this perturbation cause a significant change in HAGH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of QSER1 is measured. Determine whether QSER1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of QSER1 is measured. Determine whether QSER1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and ZEB1 expression is quantified. Does this perturbation result in a significant change in ZEB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and ZEB1 expression is quantified. Does this perturbation result in a significant change in ZEB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of CTC-308K20.1 is measured. Determine whether CTC-308K20.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of CTC-308K20.1 is measured. Determine whether CTC-308K20.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3903,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ARHGAP6 expression is observed. Does this perturbation lead to a significant difference in ARHGAP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ARHGAP6 expression is observed. Does this perturbation lead to a significant difference in ARHGAP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of SDF4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of SDF4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and NUF2 expression is measured. Determine whether NUF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and NUF2 expression is measured. Determine whether NUF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2580,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of KIF4A is measured. Does this perturbation cause a significant change in KIF4A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of KIF4A is measured. Does this perturbation cause a significant change in KIF4A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2368,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor FYTTD1 expression. Decide whether this perturbation leads to a significant alteration in FYTTD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor FYTTD1 expression. Decide whether this perturbation leads to a significant alteration in FYTTD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4953,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and PLB1 expression is observed. Does this perturbation lead to a significant difference in PLB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and PLB1 expression is observed. Does this perturbation lead to a significant difference in PLB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2010,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of AC015987.2 is measured. Does this perturbation cause a significant change in AC015987.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of AC015987.2 is measured. Does this perturbation cause a significant change in AC015987.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of PPP4R2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of PPP4R2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of LAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of LAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and EIF4B expression is measured. Determine whether EIF4B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and EIF4B expression is measured. Determine whether EIF4B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of KIAA1586 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of KIAA1586 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and GPR146 expression is measured. Determine whether GPR146 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and GPR146 expression is measured. Determine whether GPR146 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in RP11-471M2.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in RP11-471M2.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of NOXA1. Does this perturbation cause a significant change in NOXA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of NOXA1. Does this perturbation cause a significant change in NOXA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2473,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and SETX expression is observed. Does this perturbation lead to a significant difference in SETX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and SETX expression is observed. Does this perturbation lead to a significant difference in SETX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4853,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and STK17B expression is observed. Does this perturbation lead to a significant difference in STK17B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and STK17B expression is observed. Does this perturbation lead to a significant difference in STK17B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of RP11-573D15.9. Does perturbing QARS lead to a significant change in RP11-573D15.9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of RP11-573D15.9. Does perturbing QARS lead to a significant change in RP11-573D15.9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and DOCK11 expression is measured. Determine whether DOCK11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and DOCK11 expression is measured. Determine whether DOCK11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1803,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and LTBP1 expression is observed. Does this perturbation lead to a significant difference in LTBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and LTBP1 expression is observed. Does this perturbation lead to a significant difference in LTBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3253,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and S100A11 expression is observed. Does this perturbation lead to a significant difference in S100A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and S100A11 expression is observed. Does this perturbation lead to a significant difference in S100A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of HLA-E is measured. Determine whether HLA-E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of HLA-E is measured. Determine whether HLA-E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of EBI3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of EBI3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5080,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of GPR146 is measured. Does this perturbation cause a significant change in GPR146 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of GPR146 is measured. Does this perturbation cause a significant change in GPR146 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in RP11-499F3.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in RP11-499F3.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and CLINT1 expression is quantified. Does this perturbation result in a significant change in CLINT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and CLINT1 expression is quantified. Does this perturbation result in a significant change in CLINT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and SERPINH1 expression is measured. Determine whether SERPINH1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and SERPINH1 expression is measured. Determine whether SERPINH1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of MS4A6E. Does perturbing SEC61A1 lead to a significant change in MS4A6E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of MS4A6E. Does perturbing SEC61A1 lead to a significant change in MS4A6E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in ATP6AP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in ATP6AP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
643,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and KANSL1L expression is observed. Does this perturbation lead to a significant difference in KANSL1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and KANSL1L expression is observed. Does this perturbation lead to a significant difference in KANSL1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3373,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and LIMS1 expression is observed. Does this perturbation lead to a significant difference in LIMS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and LIMS1 expression is observed. Does this perturbation lead to a significant difference in LIMS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ARHGAP6. Does perturbing KCTD16 lead to a significant change in ARHGAP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ARHGAP6. Does perturbing KCTD16 lead to a significant change in ARHGAP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
84,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of PHF3. Does this perturbation cause a significant change in PHF3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of PHF3. Does this perturbation cause a significant change in PHF3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of IRF7. Does this perturbation cause a significant change in IRF7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of IRF7. Does this perturbation cause a significant change in IRF7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of RP11-2H8.2 is measured. Determine whether RP11-2H8.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of RP11-2H8.2 is measured. Determine whether RP11-2H8.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
648,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor KANSL1L expression. Decide whether this perturbation leads to a significant alteration in KANSL1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor KANSL1L expression. Decide whether this perturbation leads to a significant alteration in KANSL1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of CRNDE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of CRNDE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and H1FX expression is quantified. Does this perturbation result in a significant change in H1FX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and H1FX expression is quantified. Does this perturbation result in a significant change in H1FX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3993,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and RP11-242O24.5 expression is observed. Does this perturbation lead to a significant difference in RP11-242O24.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and RP11-242O24.5 expression is observed. Does this perturbation lead to a significant difference in RP11-242O24.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2448,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor RP11-119J18.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-119J18.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor RP11-119J18.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-119J18.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and WHSC1 expression is quantified. Does this perturbation result in a significant change in WHSC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and WHSC1 expression is quantified. Does this perturbation result in a significant change in WHSC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
213,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and NFE2 expression is observed. Does this perturbation lead to a significant difference in NFE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and NFE2 expression is observed. Does this perturbation lead to a significant difference in NFE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in GDF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in GDF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
208,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor KLK1 expression. Decide whether this perturbation leads to a significant alteration in KLK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor KLK1 expression. Decide whether this perturbation leads to a significant alteration in KLK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of KLK1. Does perturbing DDIT3 lead to a significant change in KLK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of KLK1. Does perturbing DDIT3 lead to a significant change in KLK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2128,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of TRAPPC10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of TRAPPC10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of AC096559.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of AC096559.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of KIF4A is measured. Determine whether KIF4A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of KIF4A is measured. Determine whether KIF4A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of ACRV1. Does perturbing DDOST lead to a significant change in ACRV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of ACRV1. Does perturbing DDOST lead to a significant change in ACRV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of GOT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of GOT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of RP11-61E11.1. Does perturbing SAMM50 lead to a significant change in RP11-61E11.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of RP11-61E11.1. Does perturbing SAMM50 lead to a significant change in RP11-61E11.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2770,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of LAMP2 is measured. Does this perturbation cause a significant change in LAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of LAMP2 is measured. Does this perturbation cause a significant change in LAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
653,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and POU2F2 expression is observed. Does this perturbation lead to a significant difference in POU2F2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and POU2F2 expression is observed. Does this perturbation lead to a significant difference in POU2F2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of PPP1R16B is measured. Determine whether PPP1R16B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of PPP1R16B is measured. Determine whether PPP1R16B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of C19orf59 is measured. Determine whether C19orf59 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of C19orf59 is measured. Determine whether C19orf59 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of CTC-308K20.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of CTC-308K20.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of NTRK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of NTRK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in NAV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in NAV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and TRIM38 expression is quantified. Does this perturbation result in a significant change in TRIM38 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and TRIM38 expression is quantified. Does this perturbation result in a significant change in TRIM38 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of HERC2 is measured. Determine whether HERC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of HERC2 is measured. Determine whether HERC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of PGM3. Does this perturbation cause a significant change in PGM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of PGM3. Does this perturbation cause a significant change in PGM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and RP11-360L9.8 expression is measured. Determine whether RP11-360L9.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and RP11-360L9.8 expression is measured. Determine whether RP11-360L9.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4283,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4450,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of CENPC is measured. Does this perturbation cause a significant change in CENPC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of CENPC is measured. Does this perturbation cause a significant change in CENPC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and CMTM6 expression is measured. Determine whether CMTM6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and CMTM6 expression is measured. Determine whether CMTM6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of PSMC1. Does this perturbation cause a significant change in PSMC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of PSMC1. Does this perturbation cause a significant change in PSMC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of EGLN3 is measured. Determine whether EGLN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of EGLN3 is measured. Determine whether EGLN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4433,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and HERPUD1 expression is observed. Does this perturbation lead to a significant difference in HERPUD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and HERPUD1 expression is observed. Does this perturbation lead to a significant difference in HERPUD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of TOB2. Does perturbing IDH3A lead to a significant change in TOB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of TOB2. Does perturbing IDH3A lead to a significant change in TOB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5123,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and CDT1 expression is observed. Does this perturbation lead to a significant difference in CDT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and CDT1 expression is observed. Does this perturbation lead to a significant difference in CDT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and SP100 expression is measured. Determine whether SP100 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and SP100 expression is measured. Determine whether SP100 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of SEPT5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of SEPT5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3530,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of FCGRT is measured. Does this perturbation cause a significant change in FCGRT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of FCGRT is measured. Does this perturbation cause a significant change in FCGRT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and S100A11 expression is measured. Determine whether S100A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and S100A11 expression is measured. Determine whether S100A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and SEC23IP expression is quantified. Does this perturbation result in a significant change in SEC23IP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and SEC23IP expression is quantified. Does this perturbation result in a significant change in SEC23IP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of TRPM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of TRPM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of PDE3B. Does perturbing DNAJC19 lead to a significant change in PDE3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of PDE3B. Does perturbing DNAJC19 lead to a significant change in PDE3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of CTCFL. Does this perturbation cause a significant change in CTCFL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of CTCFL. Does this perturbation cause a significant change in CTCFL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2283,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and TNFRSF10B expression is observed. Does this perturbation lead to a significant difference in TNFRSF10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and TNFRSF10B expression is observed. Does this perturbation lead to a significant difference in TNFRSF10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1460,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of RSAD2 is measured. Does this perturbation cause a significant change in RSAD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of RSAD2 is measured. Does this perturbation cause a significant change in RSAD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
153,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and CTSF expression is observed. Does this perturbation lead to a significant difference in CTSF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and CTSF expression is observed. Does this perturbation lead to a significant difference in CTSF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
23,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of ZNF341. Does this perturbation cause a significant change in ZNF341 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of ZNF341. Does this perturbation cause a significant change in ZNF341 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and HRK expression is quantified. Does this perturbation result in a significant change in HRK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and HRK expression is quantified. Does this perturbation result in a significant change in HRK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3223,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and ZNF789 expression is observed. Does this perturbation lead to a significant difference in ZNF789 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and ZNF789 expression is observed. Does this perturbation lead to a significant difference in ZNF789 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and CTSF expression is quantified. Does this perturbation result in a significant change in CTSF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and CTSF expression is quantified. Does this perturbation result in a significant change in CTSF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and USP34 expression is quantified. Does this perturbation result in a significant change in USP34 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and USP34 expression is quantified. Does this perturbation result in a significant change in USP34 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of AFF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of AFF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and TNFRSF10B expression is measured. Determine whether TNFRSF10B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and TNFRSF10B expression is measured. Determine whether TNFRSF10B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and PIK3R3 expression is measured. Determine whether PIK3R3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and PIK3R3 expression is measured. Determine whether PIK3R3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and C3AR1 expression is measured. Determine whether C3AR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and C3AR1 expression is measured. Determine whether C3AR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of ZNF280B. Does perturbing SOCS1 lead to a significant change in ZNF280B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of ZNF280B. Does perturbing SOCS1 lead to a significant change in ZNF280B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and KCNH7 expression is quantified. Does this perturbation result in a significant change in KCNH7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and KCNH7 expression is quantified. Does this perturbation result in a significant change in KCNH7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of EPB42 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of EPB42 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and RP11-61E11.1 expression is measured. Determine whether RP11-61E11.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and RP11-61E11.1 expression is measured. Determine whether RP11-61E11.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in SMIM14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in SMIM14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of CD46. Does perturbing CHERP lead to a significant change in CD46 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of CD46. Does perturbing CHERP lead to a significant change in CD46 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of VAMP2. Does this perturbation cause a significant change in VAMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of VAMP2. Does this perturbation cause a significant change in VAMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of HIST1H2BC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of HIST1H2BC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2653,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and IFNGR1 expression is observed. Does this perturbation lead to a significant difference in IFNGR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and IFNGR1 expression is observed. Does this perturbation lead to a significant difference in IFNGR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
933,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and RP11-863K10.7 expression is observed. Does this perturbation lead to a significant difference in RP11-863K10.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and RP11-863K10.7 expression is observed. Does this perturbation lead to a significant difference in RP11-863K10.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of RDH10. Does this perturbation cause a significant change in RDH10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of RDH10. Does this perturbation cause a significant change in RDH10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
318,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and APOBEC3D expression is measured. Determine whether APOBEC3D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and APOBEC3D expression is measured. Determine whether APOBEC3D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of TUBA1C. Does perturbing SRP72 lead to a significant change in TUBA1C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of TUBA1C. Does perturbing SRP72 lead to a significant change in TUBA1C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and PCF11 expression is quantified. Does this perturbation result in a significant change in PCF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and PCF11 expression is quantified. Does this perturbation result in a significant change in PCF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of CENPC is measured. Determine whether CENPC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of CENPC is measured. Determine whether CENPC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2973,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and HPCAL1 expression is observed. Does this perturbation lead to a significant difference in HPCAL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and HPCAL1 expression is observed. Does this perturbation lead to a significant difference in HPCAL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in USP34 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in USP34 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and CDKN2C expression is quantified. Does this perturbation result in a significant change in CDKN2C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and CDKN2C expression is quantified. Does this perturbation result in a significant change in CDKN2C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of AC018878.3 is measured. Determine whether AC018878.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of AC018878.3 is measured. Determine whether AC018878.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of YTHDF2 is measured. Determine whether YTHDF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of YTHDF2 is measured. Determine whether YTHDF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of RP11-640M9.1. Does this perturbation cause a significant change in RP11-640M9.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of RP11-640M9.1. Does this perturbation cause a significant change in RP11-640M9.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and STK17B expression is quantified. Does this perturbation result in a significant change in STK17B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and STK17B expression is quantified. Does this perturbation result in a significant change in STK17B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and SPCS2 expression is quantified. Does this perturbation result in a significant change in SPCS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and SPCS2 expression is quantified. Does this perturbation result in a significant change in SPCS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1600,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of ATP6V1B2 is measured. Does this perturbation cause a significant change in ATP6V1B2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of ATP6V1B2 is measured. Does this perturbation cause a significant change in ATP6V1B2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of POU2F2 is measured. Determine whether POU2F2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of POU2F2 is measured. Determine whether POU2F2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1783,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and KCNH7 expression is observed. Does this perturbation lead to a significant difference in KCNH7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and KCNH7 expression is observed. Does this perturbation lead to a significant difference in KCNH7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2623,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and MORF4L2 expression is observed. Does this perturbation lead to a significant difference in MORF4L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and MORF4L2 expression is observed. Does this perturbation lead to a significant difference in MORF4L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and RP11-334C17.5 expression is measured. Determine whether RP11-334C17.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and RP11-334C17.5 expression is measured. Determine whether RP11-334C17.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of VIM-AS1. Does this perturbation cause a significant change in VIM-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of VIM-AS1. Does this perturbation cause a significant change in VIM-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3368,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor SETX expression. Decide whether this perturbation leads to a significant alteration in SETX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor SETX expression. Decide whether this perturbation leads to a significant alteration in SETX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1453,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and LRIF1 expression is observed. Does this perturbation lead to a significant difference in LRIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and LRIF1 expression is observed. Does this perturbation lead to a significant difference in LRIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4890,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of KIAA1731 is measured. Does this perturbation cause a significant change in KIAA1731 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of KIAA1731 is measured. Does this perturbation cause a significant change in KIAA1731 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2290,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of KLF6 is measured. Does this perturbation cause a significant change in KLF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of KLF6 is measured. Does this perturbation cause a significant change in KLF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and KCTD1 expression is quantified. Does this perturbation result in a significant change in KCTD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and KCTD1 expression is quantified. Does this perturbation result in a significant change in KCTD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of TSNAXIP1 is measured. Determine whether TSNAXIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of TSNAXIP1 is measured. Determine whether TSNAXIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and CASP8 expression is measured. Determine whether CASP8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and CASP8 expression is measured. Determine whether CASP8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4160,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of SSBP2 is measured. Does this perturbation cause a significant change in SSBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of SSBP2 is measured. Does this perturbation cause a significant change in SSBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of ERP29 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of ERP29 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
698,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor SPCS2 expression. Decide whether this perturbation leads to a significant alteration in SPCS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor SPCS2 expression. Decide whether this perturbation leads to a significant alteration in SPCS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1513,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and TMOD3 expression is observed. Does this perturbation lead to a significant difference in TMOD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and TMOD3 expression is observed. Does this perturbation lead to a significant difference in TMOD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of PCK2 is measured. Determine whether PCK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of PCK2 is measured. Determine whether PCK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
828,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor TMEM87B expression. Decide whether this perturbation leads to a significant alteration in TMEM87B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor TMEM87B expression. Decide whether this perturbation leads to a significant alteration in TMEM87B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and DST expression is quantified. Does this perturbation result in a significant change in DST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and DST expression is quantified. Does this perturbation result in a significant change in DST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of TGOLN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of TGOLN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of EPS15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of EPS15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2878,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor RGS3 expression. Decide whether this perturbation leads to a significant alteration in RGS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor RGS3 expression. Decide whether this perturbation leads to a significant alteration in RGS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2493,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and CD58 expression is observed. Does this perturbation lead to a significant difference in CD58 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and CD58 expression is observed. Does this perturbation lead to a significant difference in CD58 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of EGLN3. Does perturbing PSMD4 lead to a significant change in EGLN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of EGLN3. Does perturbing PSMD4 lead to a significant change in EGLN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3933,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ZXDA expression is observed. Does this perturbation lead to a significant difference in ZXDA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ZXDA expression is observed. Does this perturbation lead to a significant difference in ZXDA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and LINC01031 expression is quantified. Does this perturbation result in a significant change in LINC01031 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and LINC01031 expression is quantified. Does this perturbation result in a significant change in LINC01031 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and RP11-363D14.1 expression is quantified. Does this perturbation result in a significant change in RP11-363D14.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and RP11-363D14.1 expression is quantified. Does this perturbation result in a significant change in RP11-363D14.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of KCTD1. Does this perturbation cause a significant change in KCTD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of KCTD1. Does this perturbation cause a significant change in KCTD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1168,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor KDM1B expression. Decide whether this perturbation leads to a significant alteration in KDM1B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor KDM1B expression. Decide whether this perturbation leads to a significant alteration in KDM1B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and AC015987.1 expression is measured. Determine whether AC015987.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and AC015987.1 expression is measured. Determine whether AC015987.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in SPAST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in SPAST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4158,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor PDRG1 expression. Decide whether this perturbation leads to a significant alteration in PDRG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor PDRG1 expression. Decide whether this perturbation leads to a significant alteration in PDRG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in H1FX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in H1FX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4768,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor TLK2 expression. Decide whether this perturbation leads to a significant alteration in TLK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor TLK2 expression. Decide whether this perturbation leads to a significant alteration in TLK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and PDK2 expression is quantified. Does this perturbation result in a significant change in PDK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and PDK2 expression is quantified. Does this perturbation result in a significant change in PDK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of RBM12B-AS1 is measured. Determine whether RBM12B-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of RBM12B-AS1 is measured. Determine whether RBM12B-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of PDK2. Does this perturbation cause a significant change in PDK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of PDK2. Does this perturbation cause a significant change in PDK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3588,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor RP3-465N24.6 expression. Decide whether this perturbation leads to a significant alteration in RP3-465N24.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor RP3-465N24.6 expression. Decide whether this perturbation leads to a significant alteration in RP3-465N24.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and CPQ expression is measured. Determine whether CPQ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and CPQ expression is measured. Determine whether CPQ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of STK17B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of STK17B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of CENPF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of CENPF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
44,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of LPAR5. Does this perturbation cause a significant change in LPAR5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of LPAR5. Does this perturbation cause a significant change in LPAR5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of RP11-2H8.2. Does this perturbation cause a significant change in RP11-2H8.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of RP11-2H8.2. Does this perturbation cause a significant change in RP11-2H8.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of TACC3 is measured. Determine whether TACC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of TACC3 is measured. Determine whether TACC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of CLINT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of CLINT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of PHF21A. Does perturbing DDOST lead to a significant change in PHF21A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of PHF21A. Does perturbing DDOST lead to a significant change in PHF21A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2148,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor NINJ2 expression. Decide whether this perturbation leads to a significant alteration in NINJ2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor NINJ2 expression. Decide whether this perturbation leads to a significant alteration in NINJ2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1450,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of LRIF1 is measured. Does this perturbation cause a significant change in LRIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of LRIF1 is measured. Does this perturbation cause a significant change in LRIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of LAMP2. Does perturbing HSD17B12 lead to a significant change in LAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of LAMP2. Does perturbing HSD17B12 lead to a significant change in LAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of S100A11. Does this perturbation cause a significant change in S100A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of S100A11. Does this perturbation cause a significant change in S100A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and ANKRD33 expression is measured. Determine whether ANKRD33 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and ANKRD33 expression is measured. Determine whether ANKRD33 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of UQCRB. Does this perturbation cause a significant change in UQCRB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of UQCRB. Does this perturbation cause a significant change in UQCRB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and PITPNB expression is quantified. Does this perturbation result in a significant change in PITPNB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and PITPNB expression is quantified. Does this perturbation result in a significant change in PITPNB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in IL18R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in IL18R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2380,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of DKFZP779L1853 is measured. Does this perturbation cause a significant change in DKFZP779L1853 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of DKFZP779L1853 is measured. Does this perturbation cause a significant change in DKFZP779L1853 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1813,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and NFAT5 expression is observed. Does this perturbation lead to a significant difference in NFAT5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and NFAT5 expression is observed. Does this perturbation lead to a significant difference in NFAT5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4770,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of HIST1H2BC is measured. Does this perturbation cause a significant change in HIST1H2BC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of HIST1H2BC is measured. Does this perturbation cause a significant change in HIST1H2BC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1080,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of DDX3X is measured. Does this perturbation cause a significant change in DDX3X expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of DDX3X is measured. Does this perturbation cause a significant change in DDX3X expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1290,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of RP11-573D15.9 is measured. Does this perturbation cause a significant change in RP11-573D15.9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of RP11-573D15.9 is measured. Does this perturbation cause a significant change in RP11-573D15.9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of RP11-471M2.3. Does perturbing SEC63 lead to a significant change in RP11-471M2.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of RP11-471M2.3. Does perturbing SEC63 lead to a significant change in RP11-471M2.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4358,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor ANKRD10 expression. Decide whether this perturbation leads to a significant alteration in ANKRD10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor ANKRD10 expression. Decide whether this perturbation leads to a significant alteration in ANKRD10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and C1GALT1 expression is measured. Determine whether C1GALT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and C1GALT1 expression is measured. Determine whether C1GALT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of PTPN11. Does this perturbation cause a significant change in PTPN11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of PTPN11. Does this perturbation cause a significant change in PTPN11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in SERPINF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in SERPINF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in RP1-274L7.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in RP1-274L7.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2478,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor SETX expression. Decide whether this perturbation leads to a significant alteration in SETX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor SETX expression. Decide whether this perturbation leads to a significant alteration in SETX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of MEX3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of MEX3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and QSER1 expression is measured. Determine whether QSER1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and QSER1 expression is measured. Determine whether QSER1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
948,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor RP11-789C1.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-789C1.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor RP11-789C1.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-789C1.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
28,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1990,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of TLK2 is measured. Does this perturbation cause a significant change in TLK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of TLK2 is measured. Does this perturbation cause a significant change in TLK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and SP100 expression is quantified. Does this perturbation result in a significant change in SP100 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and SP100 expression is quantified. Does this perturbation result in a significant change in SP100 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in HPCAL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in HPCAL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4420,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of RP11-157D23.2 is measured. Does this perturbation cause a significant change in RP11-157D23.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of RP11-157D23.2 is measured. Does this perturbation cause a significant change in RP11-157D23.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
14,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of P4HA2. Does this perturbation cause a significant change in P4HA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of P4HA2. Does this perturbation cause a significant change in P4HA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of PIK3R3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of PIK3R3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and ARHGAP11A expression is measured. Determine whether ARHGAP11A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and ARHGAP11A expression is measured. Determine whether ARHGAP11A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and AC079466.1 expression is measured. Determine whether AC079466.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and AC079466.1 expression is measured. Determine whether AC079466.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4950,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of PLB1 is measured. Does this perturbation cause a significant change in PLB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of PLB1 is measured. Does this perturbation cause a significant change in PLB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of UBE2V1. Does perturbing SYVN1 lead to a significant change in UBE2V1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of UBE2V1. Does perturbing SYVN1 lead to a significant change in UBE2V1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of SERPINF2. Does this perturbation cause a significant change in SERPINF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of SERPINF2. Does this perturbation cause a significant change in SERPINF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of CTD-2587M2.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of CTD-2587M2.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3173,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and MLEC expression is observed. Does this perturbation lead to a significant difference in MLEC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and MLEC expression is observed. Does this perturbation lead to a significant difference in MLEC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and PSORS1C1 expression is measured. Determine whether PSORS1C1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and PSORS1C1 expression is measured. Determine whether PSORS1C1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and RP11-381O7.3 expression is quantified. Does this perturbation result in a significant change in RP11-381O7.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and RP11-381O7.3 expression is quantified. Does this perturbation result in a significant change in RP11-381O7.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of DNTTIP2 is measured. Determine whether DNTTIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of DNTTIP2 is measured. Determine whether DNTTIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of C10orf32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of C10orf32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RAI14. Does perturbing MARS lead to a significant change in RAI14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RAI14. Does perturbing MARS lead to a significant change in RAI14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2013,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and AC015987.2 expression is observed. Does this perturbation lead to a significant difference in AC015987.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and AC015987.2 expression is observed. Does this perturbation lead to a significant difference in AC015987.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of PPM1N is measured. Determine whether PPM1N shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of PPM1N is measured. Determine whether PPM1N shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of FYTTD1. Does this perturbation cause a significant change in FYTTD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of FYTTD1. Does this perturbation cause a significant change in FYTTD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ZXDA. Does perturbing SLC35B1 lead to a significant change in ZXDA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ZXDA. Does perturbing SLC35B1 lead to a significant change in ZXDA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3148,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor DYNC1H1 expression. Decide whether this perturbation leads to a significant alteration in DYNC1H1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor DYNC1H1 expression. Decide whether this perturbation leads to a significant alteration in DYNC1H1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of SSBP2. Does perturbing COPB1 lead to a significant change in SSBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of SSBP2. Does perturbing COPB1 lead to a significant change in SSBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
82,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and PHF3 expression is quantified. Does this perturbation result in a significant change in PHF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and PHF3 expression is quantified. Does this perturbation result in a significant change in PHF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of MYH7B. Does this perturbation cause a significant change in MYH7B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of MYH7B. Does this perturbation cause a significant change in MYH7B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1603,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and ATP6V1B2 expression is observed. Does this perturbation lead to a significant difference in ATP6V1B2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and ATP6V1B2 expression is observed. Does this perturbation lead to a significant difference in ATP6V1B2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ARHGAP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ARHGAP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and NAV1 expression is quantified. Does this perturbation result in a significant change in NAV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and NAV1 expression is quantified. Does this perturbation result in a significant change in NAV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1033,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and TLN1 expression is observed. Does this perturbation lead to a significant difference in TLN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and TLN1 expression is observed. Does this perturbation lead to a significant difference in TLN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
998,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor SHOX2 expression. Decide whether this perturbation leads to a significant alteration in SHOX2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor SHOX2 expression. Decide whether this perturbation leads to a significant alteration in SHOX2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of TRIM38. Does perturbing SRP72 lead to a significant change in TRIM38 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of TRIM38. Does perturbing SRP72 lead to a significant change in TRIM38 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of RP11-212I21.4. Does perturbing GNPNAT1 lead to a significant change in RP11-212I21.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of RP11-212I21.4. Does perturbing GNPNAT1 lead to a significant change in RP11-212I21.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1463,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and RSAD2 expression is observed. Does this perturbation lead to a significant difference in RSAD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and RSAD2 expression is observed. Does this perturbation lead to a significant difference in RSAD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2670,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of CTSV is measured. Does this perturbation cause a significant change in CTSV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of CTSV is measured. Does this perturbation cause a significant change in CTSV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of RNF8 is measured. Determine whether RNF8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of RNF8 is measured. Determine whether RNF8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2520,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of RNF139-AS1 is measured. Does this perturbation cause a significant change in RNF139-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of RNF139-AS1 is measured. Does this perturbation cause a significant change in RNF139-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2178,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor LRRC4B expression. Decide whether this perturbation leads to a significant alteration in LRRC4B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor LRRC4B expression. Decide whether this perturbation leads to a significant alteration in LRRC4B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of NPDC1 is measured. Determine whether NPDC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of NPDC1 is measured. Determine whether NPDC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2720,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4000,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of IL2RB is measured. Does this perturbation cause a significant change in IL2RB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of IL2RB is measured. Does this perturbation cause a significant change in IL2RB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of PCF11. Does perturbing YIPF5 lead to a significant change in PCF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of PCF11. Does perturbing YIPF5 lead to a significant change in PCF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2573,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and ACE expression is observed. Does this perturbation lead to a significant difference in ACE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and ACE expression is observed. Does this perturbation lead to a significant difference in ACE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
738,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor BRWD3 expression. Decide whether this perturbation leads to a significant alteration in BRWD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor BRWD3 expression. Decide whether this perturbation leads to a significant alteration in BRWD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in ZNF789 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in ZNF789 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
458,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor SLFNL1 expression. Decide whether this perturbation leads to a significant alteration in SLFNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor SLFNL1 expression. Decide whether this perturbation leads to a significant alteration in SLFNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3048,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor C10orf32 expression. Decide whether this perturbation leads to a significant alteration in C10orf32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor C10orf32 expression. Decide whether this perturbation leads to a significant alteration in C10orf32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in WARS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in WARS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4943,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and RGS20 expression is observed. Does this perturbation lead to a significant difference in RGS20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and RGS20 expression is observed. Does this perturbation lead to a significant difference in RGS20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of HMGCS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of HMGCS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of CD58. Does this perturbation cause a significant change in CD58 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of CD58. Does this perturbation cause a significant change in CD58 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and C9orf64 expression is measured. Determine whether C9orf64 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and C9orf64 expression is measured. Determine whether C9orf64 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of NXF1. Does perturbing SARS lead to a significant change in NXF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of NXF1. Does perturbing SARS lead to a significant change in NXF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4588,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor VIMP expression. Decide whether this perturbation leads to a significant alteration in VIMP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor VIMP expression. Decide whether this perturbation leads to a significant alteration in VIMP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
390,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of GDF11 is measured. Does this perturbation cause a significant change in GDF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of GDF11 is measured. Does this perturbation cause a significant change in GDF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and AC008074.3 expression is quantified. Does this perturbation result in a significant change in AC008074.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and AC008074.3 expression is quantified. Does this perturbation result in a significant change in AC008074.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1028,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor HIST1H1E expression. Decide whether this perturbation leads to a significant alteration in HIST1H1E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor HIST1H1E expression. Decide whether this perturbation leads to a significant alteration in HIST1H1E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of KDM1B is measured. Determine whether KDM1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of KDM1B is measured. Determine whether KDM1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2420,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of HIST1H2AM is measured. Does this perturbation cause a significant change in HIST1H2AM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of HIST1H2AM is measured. Does this perturbation cause a significant change in HIST1H2AM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and STC2 expression is quantified. Does this perturbation result in a significant change in STC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and STC2 expression is quantified. Does this perturbation result in a significant change in STC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3088,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor TROAP expression. Decide whether this perturbation leads to a significant alteration in TROAP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor TROAP expression. Decide whether this perturbation leads to a significant alteration in TROAP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4863,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and NAV2 expression is observed. Does this perturbation lead to a significant difference in NAV2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and NAV2 expression is observed. Does this perturbation lead to a significant difference in NAV2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of BACH2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of BACH2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of PDK2 is measured. Determine whether PDK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of PDK2 is measured. Determine whether PDK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2048,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and OR2T6 expression is measured. Determine whether OR2T6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and OR2T6 expression is measured. Determine whether OR2T6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of KCNH7 is measured. Determine whether KCNH7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of KCNH7 is measured. Determine whether KCNH7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2490,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of CD58 is measured. Does this perturbation cause a significant change in CD58 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of CD58 is measured. Does this perturbation cause a significant change in CD58 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of TFPI. Does this perturbation cause a significant change in TFPI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of TFPI. Does this perturbation cause a significant change in TFPI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and AC018878.3 expression is quantified. Does this perturbation result in a significant change in AC018878.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and AC018878.3 expression is quantified. Does this perturbation result in a significant change in AC018878.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of ZEB2 is measured. Determine whether ZEB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of ZEB2 is measured. Determine whether ZEB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4438,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor HERPUD1 expression. Decide whether this perturbation leads to a significant alteration in HERPUD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor HERPUD1 expression. Decide whether this perturbation leads to a significant alteration in HERPUD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of KIAA1731. Does perturbing CARS lead to a significant change in KIAA1731 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of KIAA1731. Does perturbing CARS lead to a significant change in KIAA1731 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of RP11-435O5.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of RP11-435O5.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of EXOC3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of EXOC3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4560,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of WDR3 is measured. Does this perturbation cause a significant change in WDR3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of WDR3 is measured. Does this perturbation cause a significant change in WDR3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PHF19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PHF19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in WHSC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in WHSC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2353,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and IL13RA1 expression is observed. Does this perturbation lead to a significant difference in IL13RA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and IL13RA1 expression is observed. Does this perturbation lead to a significant difference in IL13RA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1833,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and ATP2A3 expression is observed. Does this perturbation lead to a significant difference in ATP2A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and ATP2A3 expression is observed. Does this perturbation lead to a significant difference in ATP2A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and KCNE3 expression is quantified. Does this perturbation result in a significant change in KCNE3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and KCNE3 expression is quantified. Does this perturbation result in a significant change in KCNE3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and KCNJ13 expression is quantified. Does this perturbation result in a significant change in KCNJ13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and KCNJ13 expression is quantified. Does this perturbation result in a significant change in KCNJ13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1733,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and USP37 expression is observed. Does this perturbation lead to a significant difference in USP37 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and USP37 expression is observed. Does this perturbation lead to a significant difference in USP37 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4038,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor NTRK1 expression. Decide whether this perturbation leads to a significant alteration in NTRK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor NTRK1 expression. Decide whether this perturbation leads to a significant alteration in NTRK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of RP11-445H22.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of RP11-445H22.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and LTB expression is quantified. Does this perturbation result in a significant change in LTB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and LTB expression is quantified. Does this perturbation result in a significant change in LTB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and RP11-434H6.6 expression is quantified. Does this perturbation result in a significant change in RP11-434H6.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and RP11-434H6.6 expression is quantified. Does this perturbation result in a significant change in RP11-434H6.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of S100A13. Does perturbing HSD17B12 lead to a significant change in S100A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of S100A13. Does perturbing HSD17B12 lead to a significant change in S100A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of RP11-146D12.2. Does this perturbation cause a significant change in RP11-146D12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of RP11-146D12.2. Does this perturbation cause a significant change in RP11-146D12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of CTSV. Does this perturbation cause a significant change in CTSV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of CTSV. Does this perturbation cause a significant change in CTSV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and KLK1 expression is quantified. Does this perturbation result in a significant change in KLK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and KLK1 expression is quantified. Does this perturbation result in a significant change in KLK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of PCK2. Does perturbing SEC61A1 lead to a significant change in PCK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of PCK2. Does perturbing SEC61A1 lead to a significant change in PCK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in GPR146 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in GPR146 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3503,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1018,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor KCNE3 expression. Decide whether this perturbation leads to a significant alteration in KCNE3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor KCNE3 expression. Decide whether this perturbation leads to a significant alteration in KCNE3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1370,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of KCTD1 is measured. Does this perturbation cause a significant change in KCTD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of KCTD1 is measured. Does this perturbation cause a significant change in KCTD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and RP11-423O2.5 expression is measured. Determine whether RP11-423O2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and RP11-423O2.5 expression is measured. Determine whether RP11-423O2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of HIST1H1E is measured. Determine whether HIST1H1E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of HIST1H1E is measured. Determine whether HIST1H1E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1208,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor GMEB1 expression. Decide whether this perturbation leads to a significant alteration in GMEB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor GMEB1 expression. Decide whether this perturbation leads to a significant alteration in GMEB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in PDRG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in PDRG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of C12orf44 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of C12orf44 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of RP11-227G15.8. Does perturbing TARS lead to a significant change in RP11-227G15.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of RP11-227G15.8. Does perturbing TARS lead to a significant change in RP11-227G15.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and RP11-322J23.1 expression is quantified. Does this perturbation result in a significant change in RP11-322J23.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and RP11-322J23.1 expression is quantified. Does this perturbation result in a significant change in RP11-322J23.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3433,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ARHGAP5 expression is observed. Does this perturbation lead to a significant difference in ARHGAP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ARHGAP5 expression is observed. Does this perturbation lead to a significant difference in ARHGAP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3770,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of ZNF341 is measured. Does this perturbation cause a significant change in ZNF341 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of ZNF341 is measured. Does this perturbation cause a significant change in ZNF341 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of PARP11. Does perturbing TIMM44 lead to a significant change in PARP11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of PARP11. Does perturbing TIMM44 lead to a significant change in PARP11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2783,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and S100A13 expression is observed. Does this perturbation lead to a significant difference in S100A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and S100A13 expression is observed. Does this perturbation lead to a significant difference in S100A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and IL2RB expression is measured. Determine whether IL2RB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and IL2RB expression is measured. Determine whether IL2RB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of RAD51AP1. Does perturbing SPCS2 lead to a significant change in RAD51AP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of RAD51AP1. Does perturbing SPCS2 lead to a significant change in RAD51AP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3323,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and NPAT expression is observed. Does this perturbation lead to a significant difference in NPAT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and NPAT expression is observed. Does this perturbation lead to a significant difference in NPAT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of ANPEP. Does this perturbation cause a significant change in ANPEP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of ANPEP. Does this perturbation cause a significant change in ANPEP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2278,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor PSORS1C1 expression. Decide whether this perturbation leads to a significant alteration in PSORS1C1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor PSORS1C1 expression. Decide whether this perturbation leads to a significant alteration in PSORS1C1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of VAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of VAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in ROCK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in ROCK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of NFE2L3 is measured. Determine whether NFE2L3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of NFE2L3 is measured. Determine whether NFE2L3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4910,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of CMTM6 is measured. Does this perturbation cause a significant change in CMTM6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of CMTM6 is measured. Does this perturbation cause a significant change in CMTM6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and HIST1H3D expression is measured. Determine whether HIST1H3D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and HIST1H3D expression is measured. Determine whether HIST1H3D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and TTC18 expression is measured. Determine whether TTC18 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and TTC18 expression is measured. Determine whether TTC18 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of STK17B. Does this perturbation cause a significant change in STK17B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of STK17B. Does this perturbation cause a significant change in STK17B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1560,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of DOCK8 is measured. Does this perturbation cause a significant change in DOCK8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of DOCK8 is measured. Does this perturbation cause a significant change in DOCK8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in FAM114A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in FAM114A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in CTC-308K20.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in CTC-308K20.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in RP11-227G15.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in RP11-227G15.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and REST expression is quantified. Does this perturbation result in a significant change in REST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and REST expression is quantified. Does this perturbation result in a significant change in REST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4790,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of ANPEP is measured. Does this perturbation cause a significant change in ANPEP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of ANPEP is measured. Does this perturbation cause a significant change in ANPEP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of H3F3B. Does this perturbation cause a significant change in H3F3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of H3F3B. Does this perturbation cause a significant change in H3F3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of AC079466.1. Does this perturbation cause a significant change in AC079466.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of AC079466.1. Does this perturbation cause a significant change in AC079466.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4103,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and LINC00938 expression is observed. Does this perturbation lead to a significant difference in LINC00938 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and LINC00938 expression is observed. Does this perturbation lead to a significant difference in LINC00938 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of RP11-181G12.2. Does this perturbation cause a significant change in RP11-181G12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of RP11-181G12.2. Does this perturbation cause a significant change in RP11-181G12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of PIK3IP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of PIK3IP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1848,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor OR2T6 expression. Decide whether this perturbation leads to a significant alteration in OR2T6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor OR2T6 expression. Decide whether this perturbation leads to a significant alteration in OR2T6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of TNFRSF10B. Does perturbing DDOST lead to a significant change in TNFRSF10B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of TNFRSF10B. Does perturbing DDOST lead to a significant change in TNFRSF10B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4573,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of TRPM4. Does this perturbation cause a significant change in TRPM4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of TRPM4. Does this perturbation cause a significant change in TRPM4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of GPR146 is measured. Determine whether GPR146 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of GPR146 is measured. Determine whether GPR146 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of SEPT5. Does this perturbation cause a significant change in SEPT5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of SEPT5. Does this perturbation cause a significant change in SEPT5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of RCBTB2. Does this perturbation cause a significant change in RCBTB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of RCBTB2. Does this perturbation cause a significant change in RCBTB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and TMEM87B expression is measured. Determine whether TMEM87B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and TMEM87B expression is measured. Determine whether TMEM87B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1498,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor RP11-24F11.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-24F11.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor RP11-24F11.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-24F11.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RGS20 is measured. Determine whether RGS20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RGS20 is measured. Determine whether RGS20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in RP11-666A20.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in RP11-666A20.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in ATXN7L3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in ATXN7L3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of DKFZP779L1853. Does perturbing HSPA9 lead to a significant change in DKFZP779L1853 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of DKFZP779L1853. Does perturbing HSPA9 lead to a significant change in DKFZP779L1853 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of SPINK5. Does this perturbation cause a significant change in SPINK5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of SPINK5. Does this perturbation cause a significant change in SPINK5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4893,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and KIAA1731 expression is observed. Does this perturbation lead to a significant difference in KIAA1731 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and KIAA1731 expression is observed. Does this perturbation lead to a significant difference in KIAA1731 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of VPS41 is measured. Determine whether VPS41 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of VPS41 is measured. Determine whether VPS41 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of TTC32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of TTC32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
218,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor NFE2 expression. Decide whether this perturbation leads to a significant alteration in NFE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor NFE2 expression. Decide whether this perturbation leads to a significant alteration in NFE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of PARP11 is measured. Determine whether PARP11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of PARP11 is measured. Determine whether PARP11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of TACC3. Does this perturbation cause a significant change in TACC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of TACC3. Does this perturbation cause a significant change in TACC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of DOK3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of DOK3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of RP11-363D14.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of RP11-363D14.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4293,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and RP11-360L9.8 expression is observed. Does this perturbation lead to a significant difference in RP11-360L9.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and RP11-360L9.8 expression is observed. Does this perturbation lead to a significant difference in RP11-360L9.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3068,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PHF19 expression. Decide whether this perturbation leads to a significant alteration in PHF19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PHF19 expression. Decide whether this perturbation leads to a significant alteration in PHF19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of KANSL1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of KANSL1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1928,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor AKAP11 expression. Decide whether this perturbation leads to a significant alteration in AKAP11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor AKAP11 expression. Decide whether this perturbation leads to a significant alteration in AKAP11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of RAD51AP1. Does this perturbation cause a significant change in RAD51AP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of RAD51AP1. Does this perturbation cause a significant change in RAD51AP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of GRN. Does this perturbation cause a significant change in GRN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of GRN. Does this perturbation cause a significant change in GRN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1070,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of ADAMTS10 is measured. Does this perturbation cause a significant change in ADAMTS10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of ADAMTS10 is measured. Does this perturbation cause a significant change in ADAMTS10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
850,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of ATF6 is measured. Does this perturbation cause a significant change in ATF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of ATF6 is measured. Does this perturbation cause a significant change in ATF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3480,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of PTGS1 is measured. Does this perturbation cause a significant change in PTGS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of PTGS1 is measured. Does this perturbation cause a significant change in PTGS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
558,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor OPTN expression. Decide whether this perturbation leads to a significant alteration in OPTN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor OPTN expression. Decide whether this perturbation leads to a significant alteration in OPTN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and TACC3 expression is quantified. Does this perturbation result in a significant change in TACC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and TACC3 expression is quantified. Does this perturbation result in a significant change in TACC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of RP11-15E18.1 is measured. Determine whether RP11-15E18.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of RP11-15E18.1 is measured. Determine whether RP11-15E18.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of NSD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of NSD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of RGS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of RGS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of KLF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of KLF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and RNF19A expression is quantified. Does this perturbation result in a significant change in RNF19A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and RNF19A expression is quantified. Does this perturbation result in a significant change in RNF19A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of GATA2. Does perturbing SPCS2 lead to a significant change in GATA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of GATA2. Does perturbing SPCS2 lead to a significant change in GATA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4113,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and CDCA3 expression is observed. Does this perturbation lead to a significant difference in CDCA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and CDCA3 expression is observed. Does this perturbation lead to a significant difference in CDCA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of RP11-838N2.4. Does this perturbation cause a significant change in RP11-838N2.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of RP11-838N2.4. Does this perturbation cause a significant change in RP11-838N2.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of C1GALT1. Does this perturbation cause a significant change in C1GALT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of C1GALT1. Does this perturbation cause a significant change in C1GALT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4183,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and ANKRD33 expression is observed. Does this perturbation lead to a significant difference in ANKRD33 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and ANKRD33 expression is observed. Does this perturbation lead to a significant difference in ANKRD33 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of ZNF678 is measured. Determine whether ZNF678 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of ZNF678 is measured. Determine whether ZNF678 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1700,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of UBE2V1 is measured. Does this perturbation cause a significant change in UBE2V1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of UBE2V1 is measured. Does this perturbation cause a significant change in UBE2V1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of CMTM6. Does this perturbation cause a significant change in CMTM6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of CMTM6. Does this perturbation cause a significant change in CMTM6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and NINJ2 expression is measured. Determine whether NINJ2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and NINJ2 expression is measured. Determine whether NINJ2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and RP11-666A20.4 expression is quantified. Does this perturbation result in a significant change in RP11-666A20.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and RP11-666A20.4 expression is quantified. Does this perturbation result in a significant change in RP11-666A20.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of RP11-3D4.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of RP11-3D4.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and TROAP expression is quantified. Does this perturbation result in a significant change in TROAP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and TROAP expression is quantified. Does this perturbation result in a significant change in TROAP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and BIRC5 expression is measured. Determine whether BIRC5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and BIRC5 expression is measured. Determine whether BIRC5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
300,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of RP11-423O2.5 is measured. Does this perturbation cause a significant change in RP11-423O2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of RP11-423O2.5 is measured. Does this perturbation cause a significant change in RP11-423O2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3838,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor PLA2G15 expression. Decide whether this perturbation leads to a significant alteration in PLA2G15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor PLA2G15 expression. Decide whether this perturbation leads to a significant alteration in PLA2G15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in NOXA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in NOXA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of NFE2. Does this perturbation cause a significant change in NFE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of NFE2. Does this perturbation cause a significant change in NFE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of PTBP3. Does perturbing SLMO2 lead to a significant change in PTBP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of PTBP3. Does perturbing SLMO2 lead to a significant change in PTBP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of ANXA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of ANXA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4123,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and FOXO6 expression is observed. Does this perturbation lead to a significant difference in FOXO6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and FOXO6 expression is observed. Does this perturbation lead to a significant difference in FOXO6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and SPCS2 expression is measured. Determine whether SPCS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and SPCS2 expression is measured. Determine whether SPCS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
160,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of RIMS3 is measured. Does this perturbation cause a significant change in RIMS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of RIMS3 is measured. Does this perturbation cause a significant change in RIMS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3353,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and EXOC3L2 expression is observed. Does this perturbation lead to a significant difference in EXOC3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and EXOC3L2 expression is observed. Does this perturbation lead to a significant difference in EXOC3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
800,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of COPB1 is measured. Does this perturbation cause a significant change in COPB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of COPB1 is measured. Does this perturbation cause a significant change in COPB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in POU2F2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in POU2F2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of MORC2-AS1. Does this perturbation cause a significant change in MORC2-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of MORC2-AS1. Does this perturbation cause a significant change in MORC2-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in DDX6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in DDX6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1840,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of OR2T6 is measured. Does this perturbation cause a significant change in OR2T6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of OR2T6 is measured. Does this perturbation cause a significant change in OR2T6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and DYNC1H1 expression is quantified. Does this perturbation result in a significant change in DYNC1H1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and DYNC1H1 expression is quantified. Does this perturbation result in a significant change in DYNC1H1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1233,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and SRP72 expression is observed. Does this perturbation lead to a significant difference in SRP72 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and SRP72 expression is observed. Does this perturbation lead to a significant difference in SRP72 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of PPP1R16B. Does this perturbation cause a significant change in PPP1R16B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of PPP1R16B. Does this perturbation cause a significant change in PPP1R16B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4690,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of ANKRD11 is measured. Does this perturbation cause a significant change in ANKRD11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of ANKRD11 is measured. Does this perturbation cause a significant change in ANKRD11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in SIGLEC6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in SIGLEC6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4680,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of QSER1 is measured. Does this perturbation cause a significant change in QSER1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of QSER1 is measured. Does this perturbation cause a significant change in QSER1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of SHOX2. Does this perturbation cause a significant change in SHOX2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of SHOX2. Does this perturbation cause a significant change in SHOX2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in SRP72 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in SRP72 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and TIPARP expression is quantified. Does this perturbation result in a significant change in TIPARP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and TIPARP expression is quantified. Does this perturbation result in a significant change in TIPARP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2333,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and F2RL2 expression is observed. Does this perturbation lead to a significant difference in F2RL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and F2RL2 expression is observed. Does this perturbation lead to a significant difference in F2RL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5028,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor RP11-430H10.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-430H10.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor RP11-430H10.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-430H10.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of KIAA0922. Does perturbing PTDSS1 lead to a significant change in KIAA0922 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of KIAA0922. Does perturbing PTDSS1 lead to a significant change in KIAA0922 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
51,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of C6orf48. Does perturbing CREB1 lead to a significant change in C6orf48 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of C6orf48. Does perturbing CREB1 lead to a significant change in C6orf48 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and SPAST expression is quantified. Does this perturbation result in a significant change in SPAST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and SPAST expression is quantified. Does this perturbation result in a significant change in SPAST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of CTC-550B14.7. Does this perturbation cause a significant change in CTC-550B14.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of CTC-550B14.7. Does this perturbation cause a significant change in CTC-550B14.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of RSL24D1. Does this perturbation cause a significant change in RSL24D1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of RSL24D1. Does this perturbation cause a significant change in RSL24D1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and ERP29 expression is quantified. Does this perturbation result in a significant change in ERP29 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and ERP29 expression is quantified. Does this perturbation result in a significant change in ERP29 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
343,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and MS4A6E expression is observed. Does this perturbation lead to a significant difference in MS4A6E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and MS4A6E expression is observed. Does this perturbation lead to a significant difference in MS4A6E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of DDX3X. Does perturbing SOCS1 lead to a significant change in DDX3X expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of DDX3X. Does perturbing SOCS1 lead to a significant change in DDX3X expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in LTB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in LTB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of TMEM87B is measured. Determine whether TMEM87B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of TMEM87B is measured. Determine whether TMEM87B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ARHGAP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ARHGAP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4688,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor QSER1 expression. Decide whether this perturbation leads to a significant alteration in QSER1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor QSER1 expression. Decide whether this perturbation leads to a significant alteration in QSER1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in TLN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in TLN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and TMOD3 expression is measured. Determine whether TMOD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and TMOD3 expression is measured. Determine whether TMOD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2860,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of PIK3IP1 is measured. Does this perturbation cause a significant change in PIK3IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of PIK3IP1 is measured. Does this perturbation cause a significant change in PIK3IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
840,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of ATP5EP2. Does this perturbation cause a significant change in ATP5EP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of ATP5EP2. Does this perturbation cause a significant change in ATP5EP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3950,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of SERPINF2 is measured. Does this perturbation cause a significant change in SERPINF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of SERPINF2 is measured. Does this perturbation cause a significant change in SERPINF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of H3F3B. Does perturbing TELO2 lead to a significant change in H3F3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of H3F3B. Does perturbing TELO2 lead to a significant change in H3F3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of TAP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of TAP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3043,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and C10orf32 expression is observed. Does this perturbation lead to a significant difference in C10orf32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and C10orf32 expression is observed. Does this perturbation lead to a significant difference in C10orf32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5130,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of CTC-308K20.1 is measured. Does this perturbation cause a significant change in CTC-308K20.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of CTC-308K20.1 is measured. Does this perturbation cause a significant change in CTC-308K20.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and HIST1H1E expression is quantified. Does this perturbation result in a significant change in HIST1H1E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and HIST1H1E expression is quantified. Does this perturbation result in a significant change in HIST1H1E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of SRP72 is measured. Determine whether SRP72 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of SRP72 is measured. Determine whether SRP72 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and FAM212A expression is quantified. Does this perturbation result in a significant change in FAM212A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and FAM212A expression is quantified. Does this perturbation result in a significant change in FAM212A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of HAGH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of HAGH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1583,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and NFE2L3 expression is observed. Does this perturbation lead to a significant difference in NFE2L3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and NFE2L3 expression is observed. Does this perturbation lead to a significant difference in NFE2L3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3203,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and GSN expression is observed. Does this perturbation lead to a significant difference in GSN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and GSN expression is observed. Does this perturbation lead to a significant difference in GSN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3718,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor C17orf64 expression. Decide whether this perturbation leads to a significant alteration in C17orf64 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor C17orf64 expression. Decide whether this perturbation leads to a significant alteration in C17orf64 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of PPP1R16B is measured. Determine whether PPP1R16B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of PPP1R16B is measured. Determine whether PPP1R16B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1243,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and CYP17A1-AS1 expression is observed. Does this perturbation lead to a significant difference in CYP17A1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and CYP17A1-AS1 expression is observed. Does this perturbation lead to a significant difference in CYP17A1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of HLA-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of HLA-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
36,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of CASP4 is measured. Determine whether CASP4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of CASP4 is measured. Determine whether CASP4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in EPS15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in EPS15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of RP11-254F7.4 is measured. Determine whether RP11-254F7.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of RP11-254F7.4 is measured. Determine whether RP11-254F7.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of GDF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of GDF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3348,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor SIGLEC6 expression. Decide whether this perturbation leads to a significant alteration in SIGLEC6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor SIGLEC6 expression. Decide whether this perturbation leads to a significant alteration in SIGLEC6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in ZP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in ZP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RAI14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RAI14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and NOXA1 expression is quantified. Does this perturbation result in a significant change in NOXA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and NOXA1 expression is quantified. Does this perturbation result in a significant change in NOXA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
600,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of PBDC1 is measured. Does this perturbation cause a significant change in PBDC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of PBDC1 is measured. Does this perturbation cause a significant change in PBDC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of LRIF1 is measured. Determine whether LRIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of LRIF1 is measured. Determine whether LRIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3460,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of CHST12 is measured. Does this perturbation cause a significant change in CHST12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of CHST12 is measured. Does this perturbation cause a significant change in CHST12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1048,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor HRK expression. Decide whether this perturbation leads to a significant alteration in HRK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor HRK expression. Decide whether this perturbation leads to a significant alteration in HRK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of P4HB. Does perturbing COPZ1 lead to a significant change in P4HB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of P4HB. Does perturbing COPZ1 lead to a significant change in P4HB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and SPEN expression is quantified. Does this perturbation result in a significant change in SPEN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and SPEN expression is quantified. Does this perturbation result in a significant change in SPEN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of C12orf44. Does perturbing SEL1L lead to a significant change in C12orf44 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of C12orf44. Does perturbing SEL1L lead to a significant change in C12orf44 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2100,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of PTAR1 is measured. Does this perturbation cause a significant change in PTAR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of PTAR1 is measured. Does this perturbation cause a significant change in PTAR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2263,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and C6orf120 expression is observed. Does this perturbation lead to a significant difference in C6orf120 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and C6orf120 expression is observed. Does this perturbation lead to a significant difference in C6orf120 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1138,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of KCTD19. Does this perturbation cause a significant change in KCTD19 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of KCTD19. Does this perturbation cause a significant change in KCTD19 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and EGLN3 expression is quantified. Does this perturbation result in a significant change in EGLN3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and EGLN3 expression is quantified. Does this perturbation result in a significant change in EGLN3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2110,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of PELO is measured. Does this perturbation cause a significant change in PELO expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of PELO is measured. Does this perturbation cause a significant change in PELO expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of AP000688.8 is measured. Determine whether AP000688.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of AP000688.8 is measured. Determine whether AP000688.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in KCNE3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in KCNE3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4130,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of WDR72 is measured. Does this perturbation cause a significant change in WDR72 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of WDR72 is measured. Does this perturbation cause a significant change in WDR72 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2608,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor CTCFL expression. Decide whether this perturbation leads to a significant alteration in CTCFL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor CTCFL expression. Decide whether this perturbation leads to a significant alteration in CTCFL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3228,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor ZNF789 expression. Decide whether this perturbation leads to a significant alteration in ZNF789 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor ZNF789 expression. Decide whether this perturbation leads to a significant alteration in ZNF789 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of NAV1 is measured. Determine whether NAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of NAV1 is measured. Determine whether NAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of CTBS. Does perturbing PPWD1 lead to a significant change in CTBS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of CTBS. Does perturbing PPWD1 lead to a significant change in CTBS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ARHGAP6 expression is quantified. Does this perturbation result in a significant change in ARHGAP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ARHGAP6 expression is quantified. Does this perturbation result in a significant change in ARHGAP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of HERC2. Does perturbing DARS lead to a significant change in HERC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of HERC2. Does perturbing DARS lead to a significant change in HERC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of PPP1R16B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of PPP1R16B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and HMGCS1 expression is measured. Determine whether HMGCS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and HMGCS1 expression is measured. Determine whether HMGCS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of DDX6. Does this perturbation cause a significant change in DDX6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of DDX6. Does this perturbation cause a significant change in DDX6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and NOX5 expression is measured. Determine whether NOX5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and NOX5 expression is measured. Determine whether NOX5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of KCNJ13. Does perturbing EIF2S1 lead to a significant change in KCNJ13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of KCNJ13. Does perturbing EIF2S1 lead to a significant change in KCNJ13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and RP11-16E12.1 expression is quantified. Does this perturbation result in a significant change in RP11-16E12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and RP11-16E12.1 expression is quantified. Does this perturbation result in a significant change in RP11-16E12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
73,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and CEBPG expression is observed. Does this perturbation lead to a significant difference in CEBPG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and CEBPG expression is observed. Does this perturbation lead to a significant difference in CEBPG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and NCKAP1L expression is quantified. Does this perturbation result in a significant change in NCKAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and NCKAP1L expression is quantified. Does this perturbation result in a significant change in NCKAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2213,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and ACSM3 expression is observed. Does this perturbation lead to a significant difference in ACSM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and ACSM3 expression is observed. Does this perturbation lead to a significant difference in ACSM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of POU2F2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of POU2F2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of CASP8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of CASP8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1368,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor ZNF678 expression. Decide whether this perturbation leads to a significant alteration in ZNF678 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor ZNF678 expression. Decide whether this perturbation leads to a significant alteration in ZNF678 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of PTGS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of PTGS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of DKFZP779L1853 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of DKFZP779L1853 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and GUSB expression is quantified. Does this perturbation result in a significant change in GUSB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and GUSB expression is quantified. Does this perturbation result in a significant change in GUSB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3620,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of NRIP1 is measured. Does this perturbation cause a significant change in NRIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of NRIP1 is measured. Does this perturbation cause a significant change in NRIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4298,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor RP11-360L9.8 expression. Decide whether this perturbation leads to a significant alteration in RP11-360L9.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor RP11-360L9.8 expression. Decide whether this perturbation leads to a significant alteration in RP11-360L9.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and SPEN expression is quantified. Does this perturbation result in a significant change in SPEN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and SPEN expression is quantified. Does this perturbation result in a significant change in SPEN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of VIMP. Does this perturbation cause a significant change in VIMP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of VIMP. Does this perturbation cause a significant change in VIMP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1413,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and NOXA1 expression is observed. Does this perturbation lead to a significant difference in NOXA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and NOXA1 expression is observed. Does this perturbation lead to a significant difference in NOXA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of PPP1R16B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of PPP1R16B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of RNF8. Does this perturbation cause a significant change in RNF8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of RNF8. Does this perturbation cause a significant change in RNF8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3598,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor RP11-2H8.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-2H8.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor RP11-2H8.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-2H8.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of TMEM60. Does this perturbation cause a significant change in TMEM60 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of TMEM60. Does this perturbation cause a significant change in TMEM60 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and CASP8 expression is quantified. Does this perturbation result in a significant change in CASP8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and CASP8 expression is quantified. Does this perturbation result in a significant change in CASP8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and IL2RB expression is measured. Determine whether IL2RB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and IL2RB expression is measured. Determine whether IL2RB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of RP11-328J2.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of RP11-328J2.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and GDF11 expression is measured. Determine whether GDF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and GDF11 expression is measured. Determine whether GDF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2383,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and DKFZP779L1853 expression is observed. Does this perturbation lead to a significant difference in DKFZP779L1853 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and DKFZP779L1853 expression is observed. Does this perturbation lead to a significant difference in DKFZP779L1853 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1470,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of ARHGAP30 is measured. Does this perturbation cause a significant change in ARHGAP30 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of ARHGAP30 is measured. Does this perturbation cause a significant change in ARHGAP30 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and RGS20 expression is quantified. Does this perturbation result in a significant change in RGS20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and RGS20 expression is quantified. Does this perturbation result in a significant change in RGS20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
880,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of GATA3 is measured. Does this perturbation cause a significant change in GATA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of GATA3 is measured. Does this perturbation cause a significant change in GATA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and SNHG10 expression is measured. Determine whether SNHG10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and SNHG10 expression is measured. Determine whether SNHG10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in ANKRD33 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in ANKRD33 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4300,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of GCKR is measured. Does this perturbation cause a significant change in GCKR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of GCKR is measured. Does this perturbation cause a significant change in GCKR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in OPTN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in OPTN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4978,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor TMEM60 expression. Decide whether this perturbation leads to a significant alteration in TMEM60 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor TMEM60 expression. Decide whether this perturbation leads to a significant alteration in TMEM60 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and S100A13 expression is quantified. Does this perturbation result in a significant change in S100A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and S100A13 expression is quantified. Does this perturbation result in a significant change in S100A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of RP11-322J23.1. Does perturbing SEC61G lead to a significant change in RP11-322J23.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of RP11-322J23.1. Does perturbing SEC61G lead to a significant change in RP11-322J23.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and KLK1 expression is measured. Determine whether KLK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and KLK1 expression is measured. Determine whether KLK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of UBE3A. Does perturbing DDRGK1 lead to a significant change in UBE3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of UBE3A. Does perturbing DDRGK1 lead to a significant change in UBE3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of ANXA4. Does perturbing DAD1 lead to a significant change in ANXA4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of ANXA4. Does perturbing DAD1 lead to a significant change in ANXA4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of NFE2L3. Does perturbing XRN1 lead to a significant change in NFE2L3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of NFE2L3. Does perturbing XRN1 lead to a significant change in NFE2L3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in AC104532.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in AC104532.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RAI14 expression is quantified. Does this perturbation result in a significant change in RAI14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RAI14 expression is quantified. Does this perturbation result in a significant change in RAI14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of RSAD2. Does perturbing MRGBP lead to a significant change in RSAD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of RSAD2. Does perturbing MRGBP lead to a significant change in RSAD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in SETX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in SETX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of MANF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of MANF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of RP11-181G12.2. Does perturbing SRPRB lead to a significant change in RP11-181G12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of RP11-181G12.2. Does perturbing SRPRB lead to a significant change in RP11-181G12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
60,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RIOK3 is measured. Does this perturbation cause a significant change in RIOK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RIOK3 is measured. Does this perturbation cause a significant change in RIOK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and LBX1 expression is measured. Determine whether LBX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and LBX1 expression is measured. Determine whether LBX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in PAK1IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in PAK1IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and CTSV expression is measured. Determine whether CTSV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and CTSV expression is measured. Determine whether CTSV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of JUND. Does perturbing DAD1 lead to a significant change in JUND expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of JUND. Does perturbing DAD1 lead to a significant change in JUND expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4570,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2630,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of HAGH is measured. Does this perturbation cause a significant change in HAGH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of HAGH is measured. Does this perturbation cause a significant change in HAGH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
808,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor COPB1 expression. Decide whether this perturbation leads to a significant alteration in COPB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor COPB1 expression. Decide whether this perturbation leads to a significant alteration in COPB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and IL2RB expression is quantified. Does this perturbation result in a significant change in IL2RB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and IL2RB expression is quantified. Does this perturbation result in a significant change in IL2RB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of TXNIP. Does perturbing SLC39A7 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of TXNIP. Does perturbing SLC39A7 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and LTBP1 expression is measured. Determine whether LTBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and LTBP1 expression is measured. Determine whether LTBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of AC012594.1. Does perturbing ATP5B lead to a significant change in AC012594.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of AC012594.1. Does perturbing ATP5B lead to a significant change in AC012594.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1930,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of GUSB is measured. Does this perturbation cause a significant change in GUSB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of GUSB is measured. Does this perturbation cause a significant change in GUSB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
450,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of SLFNL1 is measured. Does this perturbation cause a significant change in SLFNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of SLFNL1 is measured. Does this perturbation cause a significant change in SLFNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4210,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of CD46 is measured. Does this perturbation cause a significant change in CD46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of CD46 is measured. Does this perturbation cause a significant change in CD46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4620,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of KCNQ1OT1 is measured. Does this perturbation cause a significant change in KCNQ1OT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of KCNQ1OT1 is measured. Does this perturbation cause a significant change in KCNQ1OT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of C12orf44 is measured. Determine whether C12orf44 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of C12orf44 is measured. Determine whether C12orf44 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of GDF11. Does perturbing EIF2B4 lead to a significant change in GDF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of GDF11. Does perturbing EIF2B4 lead to a significant change in GDF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and VIMP expression is measured. Determine whether VIMP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and VIMP expression is measured. Determine whether VIMP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of RIMS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of RIMS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RP11-685N10.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RP11-685N10.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and RP11-90P5.2 expression is quantified. Does this perturbation result in a significant change in RP11-90P5.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and RP11-90P5.2 expression is quantified. Does this perturbation result in a significant change in RP11-90P5.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of CCDC69. Does this perturbation cause a significant change in CCDC69 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of CCDC69. Does this perturbation cause a significant change in CCDC69 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in CENPC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in CENPC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
66,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RIOK3 is measured. Determine whether RIOK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RIOK3 is measured. Determine whether RIOK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
25,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1798,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor PKDCC expression. Decide whether this perturbation leads to a significant alteration in PKDCC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor PKDCC expression. Decide whether this perturbation leads to a significant alteration in PKDCC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of RP3-465N24.6 is measured. Determine whether RP3-465N24.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of RP3-465N24.6 is measured. Determine whether RP3-465N24.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of MTPN. Does this perturbation cause a significant change in MTPN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of MTPN. Does this perturbation cause a significant change in MTPN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of RP11-16E12.1. Does perturbing TTI1 lead to a significant change in RP11-16E12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of RP11-16E12.1. Does perturbing TTI1 lead to a significant change in RP11-16E12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2820,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of PSMC1 is measured. Does this perturbation cause a significant change in PSMC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of PSMC1 is measured. Does this perturbation cause a significant change in PSMC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of ARHGAP30. Does this perturbation cause a significant change in ARHGAP30 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of ARHGAP30. Does this perturbation cause a significant change in ARHGAP30 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of HPCAL1 is measured. Determine whether HPCAL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of HPCAL1 is measured. Determine whether HPCAL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
86,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of PHF3 is measured. Determine whether PHF3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of PHF3 is measured. Determine whether PHF3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and HIST1H2AM expression is quantified. Does this perturbation result in a significant change in HIST1H2AM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and HIST1H2AM expression is quantified. Does this perturbation result in a significant change in HIST1H2AM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of IL18R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of IL18R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and SAMM50 expression is quantified. Does this perturbation result in a significant change in SAMM50 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and SAMM50 expression is quantified. Does this perturbation result in a significant change in SAMM50 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4613,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and P4HB expression is observed. Does this perturbation lead to a significant difference in P4HB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and P4HB expression is observed. Does this perturbation lead to a significant difference in P4HB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of UHRF1BP1L is measured. Determine whether UHRF1BP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of UHRF1BP1L is measured. Determine whether UHRF1BP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and GUSB expression is quantified. Does this perturbation result in a significant change in GUSB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and GUSB expression is quantified. Does this perturbation result in a significant change in GUSB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of NOX5. Does this perturbation cause a significant change in NOX5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of NOX5. Does this perturbation cause a significant change in NOX5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and RILPL2 expression is quantified. Does this perturbation result in a significant change in RILPL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and RILPL2 expression is quantified. Does this perturbation result in a significant change in RILPL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
550,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of OPTN is measured. Does this perturbation cause a significant change in OPTN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of OPTN is measured. Does this perturbation cause a significant change in OPTN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of PCK2. Does this perturbation cause a significant change in PCK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of PCK2. Does this perturbation cause a significant change in PCK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of RP11-863K10.7. Does this perturbation cause a significant change in RP11-863K10.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of RP11-863K10.7. Does this perturbation cause a significant change in RP11-863K10.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and MBNL1 expression is measured. Determine whether MBNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and MBNL1 expression is measured. Determine whether MBNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of ACE is measured. Determine whether ACE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of ACE is measured. Determine whether ACE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of RP11-61E11.1 is measured. Determine whether RP11-61E11.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of RP11-61E11.1 is measured. Determine whether RP11-61E11.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and ZNF341 expression is measured. Determine whether ZNF341 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and ZNF341 expression is measured. Determine whether ZNF341 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and HERPUD1 expression is measured. Determine whether HERPUD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and HERPUD1 expression is measured. Determine whether HERPUD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of NUF2 is measured. Determine whether NUF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of NUF2 is measured. Determine whether NUF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2238,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor FAM212A expression. Decide whether this perturbation leads to a significant alteration in FAM212A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor FAM212A expression. Decide whether this perturbation leads to a significant alteration in FAM212A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and CTD-2001C12.1 expression is measured. Determine whether CTD-2001C12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and CTD-2001C12.1 expression is measured. Determine whether CTD-2001C12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
47,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of LPAR5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of LPAR5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of PTAR1. Does this perturbation cause a significant change in PTAR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of PTAR1. Does this perturbation cause a significant change in PTAR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of RP13-216E22.4. Does perturbing MRPL39 lead to a significant change in RP13-216E22.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of RP13-216E22.4. Does perturbing MRPL39 lead to a significant change in RP13-216E22.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of DDX6 is measured. Determine whether DDX6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of DDX6 is measured. Determine whether DDX6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4848,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor EPS15 expression. Decide whether this perturbation leads to a significant alteration in EPS15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor EPS15 expression. Decide whether this perturbation leads to a significant alteration in EPS15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and SNRNP25 expression is quantified. Does this perturbation result in a significant change in SNRNP25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and SNRNP25 expression is quantified. Does this perturbation result in a significant change in SNRNP25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and ZNF292 expression is quantified. Does this perturbation result in a significant change in ZNF292 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and ZNF292 expression is quantified. Does this perturbation result in a significant change in ZNF292 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in YTHDF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in YTHDF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3080,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of TROAP is measured. Does this perturbation cause a significant change in TROAP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of TROAP is measured. Does this perturbation cause a significant change in TROAP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of CTD-2001C12.1. Does perturbing YIPF5 lead to a significant change in CTD-2001C12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of CTD-2001C12.1. Does perturbing YIPF5 lead to a significant change in CTD-2001C12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4543,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and CLDN11 expression is observed. Does this perturbation lead to a significant difference in CLDN11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and CLDN11 expression is observed. Does this perturbation lead to a significant difference in CLDN11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in TRIM24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in TRIM24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of KHDC1L. Does this perturbation cause a significant change in KHDC1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of KHDC1L. Does this perturbation cause a significant change in KHDC1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of CTD-2521M24.9 is measured. Determine whether CTD-2521M24.9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of CTD-2521M24.9 is measured. Determine whether CTD-2521M24.9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1530,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of C12orf44 is measured. Does this perturbation cause a significant change in C12orf44 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of C12orf44 is measured. Does this perturbation cause a significant change in C12orf44 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4093,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and DSC2 expression is observed. Does this perturbation lead to a significant difference in DSC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and DSC2 expression is observed. Does this perturbation lead to a significant difference in DSC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of KCNH7. Does this perturbation cause a significant change in KCNH7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of KCNH7. Does this perturbation cause a significant change in KCNH7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of RP11-499F3.2 is measured. Determine whether RP11-499F3.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of RP11-499F3.2 is measured. Determine whether RP11-499F3.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PIF1 expression is measured. Determine whether PIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PIF1 expression is measured. Determine whether PIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3453,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ZFP36L2 expression is observed. Does this perturbation lead to a significant difference in ZFP36L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ZFP36L2 expression is observed. Does this perturbation lead to a significant difference in ZFP36L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of SIGLEC6. Does perturbing PSMD4 lead to a significant change in SIGLEC6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of SIGLEC6. Does perturbing PSMD4 lead to a significant change in SIGLEC6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of KCTD19. Does perturbing MANF lead to a significant change in KCTD19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of KCTD19. Does perturbing MANF lead to a significant change in KCTD19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and QSER1 expression is measured. Determine whether QSER1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and QSER1 expression is measured. Determine whether QSER1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ARHGAP5. Does this perturbation cause a significant change in ARHGAP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ARHGAP5. Does this perturbation cause a significant change in ARHGAP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and TAP1 expression is measured. Determine whether TAP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and TAP1 expression is measured. Determine whether TAP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3583,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and RP3-465N24.6 expression is observed. Does this perturbation lead to a significant difference in RP3-465N24.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and RP3-465N24.6 expression is observed. Does this perturbation lead to a significant difference in RP3-465N24.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and KIAA1731 expression is quantified. Does this perturbation result in a significant change in KIAA1731 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and KIAA1731 expression is quantified. Does this perturbation result in a significant change in KIAA1731 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
7,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of ZNF429 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of ZNF429 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and NFE2L3 expression is measured. Determine whether NFE2L3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and NFE2L3 expression is measured. Determine whether NFE2L3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of HIST1H1D is measured. Determine whether HIST1H1D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of HIST1H1D is measured. Determine whether HIST1H1D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3713,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and C17orf64 expression is observed. Does this perturbation lead to a significant difference in C17orf64 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and C17orf64 expression is observed. Does this perturbation lead to a significant difference in C17orf64 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of AC018878.3. Does perturbing HSPA5 lead to a significant change in AC018878.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of AC018878.3. Does perturbing HSPA5 lead to a significant change in AC018878.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2598,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor RP11-471M2.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-471M2.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor RP11-471M2.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-471M2.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in CTD-2587M2.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in CTD-2587M2.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3758,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor KIAA1432 expression. Decide whether this perturbation leads to a significant alteration in KIAA1432 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor KIAA1432 expression. Decide whether this perturbation leads to a significant alteration in KIAA1432 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of ZC3H7A is measured. Determine whether ZC3H7A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of ZC3H7A is measured. Determine whether ZC3H7A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3063,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PHF19 expression is observed. Does this perturbation lead to a significant difference in PHF19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PHF19 expression is observed. Does this perturbation lead to a significant difference in PHF19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and ZNF678 expression is quantified. Does this perturbation result in a significant change in ZNF678 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and ZNF678 expression is quantified. Does this perturbation result in a significant change in ZNF678 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
238,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor PTPRC expression. Decide whether this perturbation leads to a significant alteration in PTPRC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor PTPRC expression. Decide whether this perturbation leads to a significant alteration in PTPRC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of RNF19A. Does this perturbation cause a significant change in RNF19A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of RNF19A. Does this perturbation cause a significant change in RNF19A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of QSER1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of QSER1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2273,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and PSORS1C1 expression is observed. Does this perturbation lead to a significant difference in PSORS1C1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and PSORS1C1 expression is observed. Does this perturbation lead to a significant difference in PSORS1C1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of DUT. Does this perturbation cause a significant change in DUT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of DUT. Does this perturbation cause a significant change in DUT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4973,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and TMEM60 expression is observed. Does this perturbation lead to a significant difference in TMEM60 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and TMEM60 expression is observed. Does this perturbation lead to a significant difference in TMEM60 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and RP11-666A20.4 expression is measured. Determine whether RP11-666A20.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and RP11-666A20.4 expression is measured. Determine whether RP11-666A20.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of TMEM60. Does perturbing SCYL1 lead to a significant change in TMEM60 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of TMEM60. Does perturbing SCYL1 lead to a significant change in TMEM60 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1758,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor ARHGAP6 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor ARHGAP6 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5098,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor TGOLN2 expression. Decide whether this perturbation leads to a significant alteration in TGOLN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor TGOLN2 expression. Decide whether this perturbation leads to a significant alteration in TGOLN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of TNFRSF10B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of TNFRSF10B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of RP11-863K10.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of RP11-863K10.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4373,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and RP11-181G12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-181G12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and RP11-181G12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-181G12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in DUSP21 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in DUSP21 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of TMEM87B. Does this perturbation cause a significant change in TMEM87B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of TMEM87B. Does this perturbation cause a significant change in TMEM87B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of SPINK5. Does perturbing EIF2B4 lead to a significant change in SPINK5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of SPINK5. Does perturbing EIF2B4 lead to a significant change in SPINK5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of RP11-132A1.4. Does this perturbation cause a significant change in RP11-132A1.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of RP11-132A1.4. Does this perturbation cause a significant change in RP11-132A1.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1178,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor BAMBI expression. Decide whether this perturbation leads to a significant alteration in BAMBI expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor BAMBI expression. Decide whether this perturbation leads to a significant alteration in BAMBI expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and MEX3B expression is measured. Determine whether MEX3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and MEX3B expression is measured. Determine whether MEX3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
960,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of ZEB2 is measured. Does this perturbation cause a significant change in ZEB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of ZEB2 is measured. Does this perturbation cause a significant change in ZEB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of ZNF280B. Does this perturbation cause a significant change in ZNF280B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of ZNF280B. Does this perturbation cause a significant change in ZNF280B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of CCRL2. Does this perturbation cause a significant change in CCRL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of CCRL2. Does this perturbation cause a significant change in CCRL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2410,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of MANF is measured. Does this perturbation cause a significant change in MANF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of MANF is measured. Does this perturbation cause a significant change in MANF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4428,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor RP11-157D23.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-157D23.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor RP11-157D23.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-157D23.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
568,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor IL32 expression. Decide whether this perturbation leads to a significant alteration in IL32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor IL32 expression. Decide whether this perturbation leads to a significant alteration in IL32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of DDIT4. Does perturbing GMPPB lead to a significant change in DDIT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of DDIT4. Does perturbing GMPPB lead to a significant change in DDIT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and ZNF789 expression is quantified. Does this perturbation result in a significant change in ZNF789 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and ZNF789 expression is quantified. Does this perturbation result in a significant change in ZNF789 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of CTSV. Does perturbing MANF lead to a significant change in CTSV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of CTSV. Does perturbing MANF lead to a significant change in CTSV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
868,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor ESCO1 expression. Decide whether this perturbation leads to a significant alteration in ESCO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor ESCO1 expression. Decide whether this perturbation leads to a significant alteration in ESCO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1323,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and NPDC1 expression is observed. Does this perturbation lead to a significant difference in NPDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and NPDC1 expression is observed. Does this perturbation lead to a significant difference in NPDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of RP11-119J18.1 is measured. Determine whether RP11-119J18.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of RP11-119J18.1 is measured. Determine whether RP11-119J18.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of AC008074.3. Does this perturbation cause a significant change in AC008074.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of AC008074.3. Does this perturbation cause a significant change in AC008074.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and EXO1 expression is quantified. Does this perturbation result in a significant change in EXO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and EXO1 expression is quantified. Does this perturbation result in a significant change in EXO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2948,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor SKIL expression. Decide whether this perturbation leads to a significant alteration in SKIL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor SKIL expression. Decide whether this perturbation leads to a significant alteration in SKIL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3788,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor LTN1 expression. Decide whether this perturbation leads to a significant alteration in LTN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor LTN1 expression. Decide whether this perturbation leads to a significant alteration in LTN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of ZNF280B. Does perturbing QARS lead to a significant change in ZNF280B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of ZNF280B. Does perturbing QARS lead to a significant change in ZNF280B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of IDH3A. Does perturbing MANF lead to a significant change in IDH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of IDH3A. Does perturbing MANF lead to a significant change in IDH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of ARHGAP30 is measured. Determine whether ARHGAP30 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of ARHGAP30 is measured. Determine whether ARHGAP30 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2530,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and PPP4R2 expression is quantified. Does this perturbation result in a significant change in PPP4R2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and PPP4R2 expression is quantified. Does this perturbation result in a significant change in PPP4R2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of P4HA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of P4HA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of LIMS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of LIMS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of CTD-2020K17.1 is measured. Determine whether CTD-2020K17.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of CTD-2020K17.1 is measured. Determine whether CTD-2020K17.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of IDS is measured. Determine whether IDS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of IDS is measured. Determine whether IDS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2003,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and C1GALT1 expression is observed. Does this perturbation lead to a significant difference in C1GALT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and C1GALT1 expression is observed. Does this perturbation lead to a significant difference in C1GALT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of RGS3 is measured. Determine whether RGS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of RGS3 is measured. Determine whether RGS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of ARSA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of ARSA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4050,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of RP11-15E18.1 is measured. Does this perturbation cause a significant change in RP11-15E18.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of RP11-15E18.1 is measured. Does this perturbation cause a significant change in RP11-15E18.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and EBI3 expression is quantified. Does this perturbation result in a significant change in EBI3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and EBI3 expression is quantified. Does this perturbation result in a significant change in EBI3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of IL18R1 is measured. Determine whether IL18R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of IL18R1 is measured. Determine whether IL18R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and PTPN11 expression is quantified. Does this perturbation result in a significant change in PTPN11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and PTPN11 expression is quantified. Does this perturbation result in a significant change in PTPN11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and CTSV expression is quantified. Does this perturbation result in a significant change in CTSV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and CTSV expression is quantified. Does this perturbation result in a significant change in CTSV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1050,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of RP11-38P22.2 is measured. Does this perturbation cause a significant change in RP11-38P22.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of RP11-38P22.2 is measured. Does this perturbation cause a significant change in RP11-38P22.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
48,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor LPAR5 expression. Decide whether this perturbation leads to a significant alteration in LPAR5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor LPAR5 expression. Decide whether this perturbation leads to a significant alteration in LPAR5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and AC104532.4 expression is quantified. Does this perturbation result in a significant change in AC104532.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and AC104532.4 expression is quantified. Does this perturbation result in a significant change in AC104532.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in MANF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in MANF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and ARHGAP6 expression is quantified. Does this perturbation result in a significant change in ARHGAP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and ARHGAP6 expression is quantified. Does this perturbation result in a significant change in ARHGAP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of ARHGAP11A is measured. Determine whether ARHGAP11A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of ARHGAP11A is measured. Determine whether ARHGAP11A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3618,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor TIPARP expression. Decide whether this perturbation leads to a significant alteration in TIPARP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor TIPARP expression. Decide whether this perturbation leads to a significant alteration in TIPARP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1960,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of ARHGDIB is measured. Does this perturbation cause a significant change in ARHGDIB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of ARHGDIB is measured. Does this perturbation cause a significant change in ARHGDIB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and RP1-274L7.1 expression is measured. Determine whether RP1-274L7.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and RP1-274L7.1 expression is measured. Determine whether RP1-274L7.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and RP11-304M2.5 expression is quantified. Does this perturbation result in a significant change in RP11-304M2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and RP11-304M2.5 expression is quantified. Does this perturbation result in a significant change in RP11-304M2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of WARS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of WARS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and ANPEP expression is measured. Determine whether ANPEP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and ANPEP expression is measured. Determine whether ANPEP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1853,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and TRAPPC10 expression is observed. Does this perturbation lead to a significant difference in TRAPPC10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and TRAPPC10 expression is observed. Does this perturbation lead to a significant difference in TRAPPC10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2870,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of RGS3 is measured. Does this perturbation cause a significant change in RGS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of RGS3 is measured. Does this perturbation cause a significant change in RGS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of SLC27A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of SLC27A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in LDLR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in LDLR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of AC012594.1 is measured. Determine whether AC012594.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of AC012594.1 is measured. Determine whether AC012594.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3638,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor SOBP expression. Decide whether this perturbation leads to a significant alteration in SOBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor SOBP expression. Decide whether this perturbation leads to a significant alteration in SOBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3553,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and CCRL2 expression is observed. Does this perturbation lead to a significant difference in CCRL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and CCRL2 expression is observed. Does this perturbation lead to a significant difference in CCRL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of EP400. Does perturbing TIMM44 lead to a significant change in EP400 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of EP400. Does perturbing TIMM44 lead to a significant change in EP400 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and C17orf64 expression is measured. Determine whether C17orf64 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and C17orf64 expression is measured. Determine whether C17orf64 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3110,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of NXF1 is measured. Does this perturbation cause a significant change in NXF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of NXF1 is measured. Does this perturbation cause a significant change in NXF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and CENPF expression is measured. Determine whether CENPF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and CENPF expression is measured. Determine whether CENPF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of PLB1. Does this perturbation cause a significant change in PLB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of PLB1. Does this perturbation cause a significant change in PLB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of TLK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of TLK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in TROAP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in TROAP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and C9orf64 expression is quantified. Does this perturbation result in a significant change in C9orf64 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and C9orf64 expression is quantified. Does this perturbation result in a significant change in C9orf64 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3913,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and TFPI expression is observed. Does this perturbation lead to a significant difference in TFPI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and TFPI expression is observed. Does this perturbation lead to a significant difference in TFPI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2303,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and H3F3B expression is measured. Determine whether H3F3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and H3F3B expression is measured. Determine whether H3F3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and TSC22D4 expression is measured. Determine whether TSC22D4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and TSC22D4 expression is measured. Determine whether TSC22D4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of CLCA1. Does perturbing TELO2 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of CLCA1. Does perturbing TELO2 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of PDE9A. Does this perturbation cause a significant change in PDE9A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of PDE9A. Does this perturbation cause a significant change in PDE9A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of RP11-573D15.2. Does this perturbation cause a significant change in RP11-573D15.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of RP11-573D15.2. Does this perturbation cause a significant change in RP11-573D15.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of RP11-227G15.8. Does this perturbation cause a significant change in RP11-227G15.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of RP11-227G15.8. Does this perturbation cause a significant change in RP11-227G15.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of AC005540.3. Does this perturbation cause a significant change in AC005540.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of AC005540.3. Does this perturbation cause a significant change in AC005540.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and ATXN7L3B expression is measured. Determine whether ATXN7L3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and ATXN7L3B expression is measured. Determine whether ATXN7L3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1398,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor NUF2 expression. Decide whether this perturbation leads to a significant alteration in NUF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor NUF2 expression. Decide whether this perturbation leads to a significant alteration in NUF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of NOX5. Does perturbing SRP72 lead to a significant change in NOX5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of NOX5. Does perturbing SRP72 lead to a significant change in NOX5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
753,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and TSNAXIP1 expression is observed. Does this perturbation lead to a significant difference in TSNAXIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and TSNAXIP1 expression is observed. Does this perturbation lead to a significant difference in TSNAXIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of JARID2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of JARID2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of ITGB2 is measured. Determine whether ITGB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of ITGB2 is measured. Determine whether ITGB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5133,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and CTC-308K20.1 expression is observed. Does this perturbation lead to a significant difference in CTC-308K20.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and CTC-308K20.1 expression is observed. Does this perturbation lead to a significant difference in CTC-308K20.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and STARD9 expression is measured. Determine whether STARD9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and STARD9 expression is measured. Determine whether STARD9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
723,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and RP11-132A1.4 expression is observed. Does this perturbation lead to a significant difference in RP11-132A1.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and RP11-132A1.4 expression is observed. Does this perturbation lead to a significant difference in RP11-132A1.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and RSAD2 expression is quantified. Does this perturbation result in a significant change in RSAD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and RSAD2 expression is quantified. Does this perturbation result in a significant change in RSAD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of HERPUD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of HERPUD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of QSER1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of QSER1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of EIF3A. Does this perturbation cause a significant change in EIF3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of EIF3A. Does this perturbation cause a significant change in EIF3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2040,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of AC015987.1. Does perturbing NEDD8 lead to a significant change in AC015987.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of AC015987.1. Does perturbing NEDD8 lead to a significant change in AC015987.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of PLA2G15. Does this perturbation cause a significant change in PLA2G15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of PLA2G15. Does this perturbation cause a significant change in PLA2G15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and CDKN2C expression is measured. Determine whether CDKN2C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and CDKN2C expression is measured. Determine whether CDKN2C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1658,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor EBI3 expression. Decide whether this perturbation leads to a significant alteration in EBI3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor EBI3 expression. Decide whether this perturbation leads to a significant alteration in EBI3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of BIRC5 is measured. Determine whether BIRC5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of BIRC5 is measured. Determine whether BIRC5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of TIPARP is measured. Determine whether TIPARP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of TIPARP is measured. Determine whether TIPARP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of C10orf32. Does perturbing EIF2B2 lead to a significant change in C10orf32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of C10orf32. Does perturbing EIF2B2 lead to a significant change in C10orf32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3658,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor KCNJ13 expression. Decide whether this perturbation leads to a significant alteration in KCNJ13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor KCNJ13 expression. Decide whether this perturbation leads to a significant alteration in KCNJ13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and IL32 expression is quantified. Does this perturbation result in a significant change in IL32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and IL32 expression is quantified. Does this perturbation result in a significant change in IL32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of FYTTD1. Does perturbing HSPA9 lead to a significant change in FYTTD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of FYTTD1. Does perturbing HSPA9 lead to a significant change in FYTTD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and DKFZP779L1853 expression is quantified. Does this perturbation result in a significant change in DKFZP779L1853 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and DKFZP779L1853 expression is quantified. Does this perturbation result in a significant change in DKFZP779L1853 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and IL2RB expression is quantified. Does this perturbation result in a significant change in IL2RB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and IL2RB expression is quantified. Does this perturbation result in a significant change in IL2RB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3153,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and SLC25A35 expression is observed. Does this perturbation lead to a significant difference in SLC25A35 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and SLC25A35 expression is observed. Does this perturbation lead to a significant difference in SLC25A35 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2183,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and CENPC expression is observed. Does this perturbation lead to a significant difference in CENPC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and CENPC expression is observed. Does this perturbation lead to a significant difference in CENPC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1488,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor WHSC1 expression. Decide whether this perturbation leads to a significant alteration in WHSC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor WHSC1 expression. Decide whether this perturbation leads to a significant alteration in WHSC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3528,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor TSPAN33 expression. Decide whether this perturbation leads to a significant alteration in TSPAN33 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor TSPAN33 expression. Decide whether this perturbation leads to a significant alteration in TSPAN33 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of KLK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of KLK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
483,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and VIM-AS1 expression is observed. Does this perturbation lead to a significant difference in VIM-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and VIM-AS1 expression is observed. Does this perturbation lead to a significant difference in VIM-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
663,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and PTBP3 expression is observed. Does this perturbation lead to a significant difference in PTBP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and PTBP3 expression is observed. Does this perturbation lead to a significant difference in PTBP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of RGS20. Does this perturbation cause a significant change in RGS20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of RGS20. Does this perturbation cause a significant change in RGS20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of LINC01137 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of LINC01137 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in RP11-322J23.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in RP11-322J23.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of MBNL1 is measured. Determine whether MBNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of MBNL1 is measured. Determine whether MBNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
670,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of MEX3B is measured. Does this perturbation cause a significant change in MEX3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of MEX3B is measured. Does this perturbation cause a significant change in MEX3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of NFE2 is measured. Determine whether NFE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of NFE2 is measured. Determine whether NFE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
26,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and SMCO1 expression is measured. Determine whether SMCO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and SMCO1 expression is measured. Determine whether SMCO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
288,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor CDRT4 expression. Decide whether this perturbation leads to a significant alteration in CDRT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor CDRT4 expression. Decide whether this perturbation leads to a significant alteration in CDRT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and H3F3B expression is quantified. Does this perturbation result in a significant change in H3F3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and H3F3B expression is quantified. Does this perturbation result in a significant change in H3F3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
130,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of TET1 is measured. Does this perturbation cause a significant change in TET1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of TET1 is measured. Does this perturbation cause a significant change in TET1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and S100A11 expression is quantified. Does this perturbation result in a significant change in S100A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and S100A11 expression is quantified. Does this perturbation result in a significant change in S100A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of HIST1H2AM. Does perturbing EIF2B4 lead to a significant change in HIST1H2AM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of HIST1H2AM. Does perturbing EIF2B4 lead to a significant change in HIST1H2AM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of SLFNL1 is measured. Determine whether SLFNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of SLFNL1 is measured. Determine whether SLFNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of GLG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of GLG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of MBNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of MBNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3178,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor MLEC expression. Decide whether this perturbation leads to a significant alteration in MLEC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor MLEC expression. Decide whether this perturbation leads to a significant alteration in MLEC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3423,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ARHGAP6 expression is observed. Does this perturbation lead to a significant difference in ARHGAP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ARHGAP6 expression is observed. Does this perturbation lead to a significant difference in ARHGAP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of ZP3. Does this perturbation cause a significant change in ZP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of ZP3. Does this perturbation cause a significant change in ZP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4510,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of HM13 is measured. Does this perturbation cause a significant change in HM13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of HM13 is measured. Does this perturbation cause a significant change in HM13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of ATP11B. Does perturbing OST4 lead to a significant change in ATP11B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of ATP11B. Does perturbing OST4 lead to a significant change in ATP11B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and RP11-430H10.1 expression is quantified. Does this perturbation result in a significant change in RP11-430H10.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and RP11-430H10.1 expression is quantified. Does this perturbation result in a significant change in RP11-430H10.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
98,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RP11-141B14.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-141B14.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RP11-141B14.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-141B14.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and SETX expression is measured. Determine whether SETX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and SETX expression is measured. Determine whether SETX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and AMOTL1 expression is quantified. Does this perturbation result in a significant change in AMOTL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and AMOTL1 expression is quantified. Does this perturbation result in a significant change in AMOTL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2208,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor CST7 expression. Decide whether this perturbation leads to a significant alteration in CST7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor CST7 expression. Decide whether this perturbation leads to a significant alteration in CST7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of KLK1 is measured. Determine whether KLK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of KLK1 is measured. Determine whether KLK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of TNFRSF10B is measured. Determine whether TNFRSF10B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of TNFRSF10B is measured. Determine whether TNFRSF10B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5108,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor PIK3R1 expression. Decide whether this perturbation leads to a significant alteration in PIK3R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor PIK3R1 expression. Decide whether this perturbation leads to a significant alteration in PIK3R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and RASGRP2 expression is measured. Determine whether RASGRP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and RASGRP2 expression is measured. Determine whether RASGRP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of PDE9A. Does perturbing DDIT3 lead to a significant change in PDE9A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of PDE9A. Does perturbing DDIT3 lead to a significant change in PDE9A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of GUSB is measured. Determine whether GUSB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of GUSB is measured. Determine whether GUSB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2190,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of SLC26A1 is measured. Does this perturbation cause a significant change in SLC26A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of SLC26A1 is measured. Does this perturbation cause a significant change in SLC26A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of RASGRP2. Does perturbing AARS lead to a significant change in RASGRP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of RASGRP2. Does perturbing AARS lead to a significant change in RASGRP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of IL13RA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of IL13RA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1938,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor GUSB expression. Decide whether this perturbation leads to a significant alteration in GUSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor GUSB expression. Decide whether this perturbation leads to a significant alteration in GUSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5153,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and ROCK1 expression is observed. Does this perturbation lead to a significant difference in ROCK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and ROCK1 expression is observed. Does this perturbation lead to a significant difference in ROCK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of TNFRSF10B is measured. Determine whether TNFRSF10B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of TNFRSF10B is measured. Determine whether TNFRSF10B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1563,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and DOCK8 expression is observed. Does this perturbation lead to a significant difference in DOCK8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and DOCK8 expression is observed. Does this perturbation lead to a significant difference in DOCK8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4403,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and RSAD2 expression is observed. Does this perturbation lead to a significant difference in RSAD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and RSAD2 expression is observed. Does this perturbation lead to a significant difference in RSAD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of LTN1. Does this perturbation cause a significant change in LTN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of LTN1. Does this perturbation cause a significant change in LTN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of TMEM60. Does perturbing TMED2 lead to a significant change in TMEM60 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of TMEM60. Does perturbing TMED2 lead to a significant change in TMEM60 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of ROCK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of ROCK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of CTD-2521M24.9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of CTD-2521M24.9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4738,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor MTPN expression. Decide whether this perturbation leads to a significant alteration in MTPN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor MTPN expression. Decide whether this perturbation leads to a significant alteration in MTPN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4653,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and KIAA1586 expression is observed. Does this perturbation lead to a significant difference in KIAA1586 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and KIAA1586 expression is observed. Does this perturbation lead to a significant difference in KIAA1586 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and GATA2 expression is measured. Determine whether GATA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and GATA2 expression is measured. Determine whether GATA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4730,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of MTPN is measured. Does this perturbation cause a significant change in MTPN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of MTPN is measured. Does this perturbation cause a significant change in MTPN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in GPRC5C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in GPRC5C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4610,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of P4HB is measured. Does this perturbation cause a significant change in P4HB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of P4HB is measured. Does this perturbation cause a significant change in P4HB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in S100A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in S100A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and TNFRSF10B expression is measured. Determine whether TNFRSF10B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and TNFRSF10B expression is measured. Determine whether TNFRSF10B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of LINC01137 is measured. Determine whether LINC01137 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of LINC01137 is measured. Determine whether LINC01137 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of IL8 is measured. Determine whether IL8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of IL8 is measured. Determine whether IL8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of RP11-390B4.5 is measured. Determine whether RP11-390B4.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of RP11-390B4.5 is measured. Determine whether RP11-390B4.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of EGLN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of EGLN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of RNF19A is measured. Determine whether RNF19A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of RNF19A is measured. Determine whether RNF19A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in SMCO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in SMCO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of RP11-181G12.2 is measured. Determine whether RP11-181G12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of RP11-181G12.2 is measured. Determine whether RP11-181G12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
198,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor PDE9A expression. Decide whether this perturbation leads to a significant alteration in PDE9A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor PDE9A expression. Decide whether this perturbation leads to a significant alteration in PDE9A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2248,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor AMOTL1 expression. Decide whether this perturbation leads to a significant alteration in AMOTL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor AMOTL1 expression. Decide whether this perturbation leads to a significant alteration in AMOTL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and JARID2 expression is quantified. Does this perturbation result in a significant change in JARID2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and JARID2 expression is quantified. Does this perturbation result in a significant change in JARID2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in CENPC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in CENPC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
480,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of VIM-AS1 is measured. Does this perturbation cause a significant change in VIM-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of VIM-AS1 is measured. Does this perturbation cause a significant change in VIM-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of IL18R1. Does perturbing CHERP lead to a significant change in IL18R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of IL18R1. Does perturbing CHERP lead to a significant change in IL18R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of USP34. Does perturbing SRPRB lead to a significant change in USP34 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of USP34. Does perturbing SRPRB lead to a significant change in USP34 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of SSBP2 is measured. Determine whether SSBP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of SSBP2 is measured. Determine whether SSBP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4780,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of PDE3B is measured. Does this perturbation cause a significant change in PDE3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of PDE3B is measured. Does this perturbation cause a significant change in PDE3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of RP11-3D4.3. Does this perturbation cause a significant change in RP11-3D4.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of RP11-3D4.3. Does this perturbation cause a significant change in RP11-3D4.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2673,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and CTSV expression is observed. Does this perturbation lead to a significant difference in CTSV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and CTSV expression is observed. Does this perturbation lead to a significant difference in CTSV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of SEC23IP. Does perturbing TMED10 lead to a significant change in SEC23IP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of SEC23IP. Does perturbing TMED10 lead to a significant change in SEC23IP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of RP11-471M2.3. Does this perturbation cause a significant change in RP11-471M2.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of RP11-471M2.3. Does this perturbation cause a significant change in RP11-471M2.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of PDE3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of PDE3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of RP11-132A1.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of RP11-132A1.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
67,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RIOK3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RIOK3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in RP3-465N24.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in RP3-465N24.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of GLG1 is measured. Determine whether GLG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of GLG1 is measured. Determine whether GLG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1973,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and CRNDE expression is observed. Does this perturbation lead to a significant difference in CRNDE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and CRNDE expression is observed. Does this perturbation lead to a significant difference in CRNDE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of CST7. Does perturbing DERL2 lead to a significant change in CST7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of CST7. Does perturbing DERL2 lead to a significant change in CST7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and ZNF678 expression is measured. Determine whether ZNF678 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and ZNF678 expression is measured. Determine whether ZNF678 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of CTC-550B14.7. Does perturbing DHDDS lead to a significant change in CTC-550B14.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of CTC-550B14.7. Does perturbing DHDDS lead to a significant change in CTC-550B14.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3320,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of NPAT is measured. Does this perturbation cause a significant change in NPAT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of NPAT is measured. Does this perturbation cause a significant change in NPAT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1173,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and BAMBI expression is observed. Does this perturbation lead to a significant difference in BAMBI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and BAMBI expression is observed. Does this perturbation lead to a significant difference in BAMBI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of ERP29. Does this perturbation cause a significant change in ERP29 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of ERP29. Does this perturbation cause a significant change in ERP29 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and WDR3 expression is measured. Determine whether WDR3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and WDR3 expression is measured. Determine whether WDR3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of TMEM87B. Does perturbing TIMM23 lead to a significant change in TMEM87B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of TMEM87B. Does perturbing TIMM23 lead to a significant change in TMEM87B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and YTHDF2 expression is quantified. Does this perturbation result in a significant change in YTHDF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and YTHDF2 expression is quantified. Does this perturbation result in a significant change in YTHDF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
833,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and RP11-138C9.1 expression is observed. Does this perturbation lead to a significant difference in RP11-138C9.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and RP11-138C9.1 expression is observed. Does this perturbation lead to a significant difference in RP11-138C9.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3500,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of MANF. Does perturbing MRPL39 lead to a significant change in MANF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of MANF. Does perturbing MRPL39 lead to a significant change in MANF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in LINC01137 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in LINC01137 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2078,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor MANF expression. Decide whether this perturbation leads to a significant alteration in MANF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor MANF expression. Decide whether this perturbation leads to a significant alteration in MANF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2748,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor DUSP21 expression. Decide whether this perturbation leads to a significant alteration in DUSP21 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor DUSP21 expression. Decide whether this perturbation leads to a significant alteration in DUSP21 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4150,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of PDRG1 is measured. Does this perturbation cause a significant change in PDRG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of PDRG1 is measured. Does this perturbation cause a significant change in PDRG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3140,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of DYNC1H1 is measured. Does this perturbation cause a significant change in DYNC1H1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of DYNC1H1 is measured. Does this perturbation cause a significant change in DYNC1H1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of TLK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of TLK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
65,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RIOK3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RIOK3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4280,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of RGS3. Does perturbing SEC61B lead to a significant change in RGS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of RGS3. Does perturbing SEC61B lead to a significant change in RGS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in QSER1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in QSER1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of RP11-334C17.5. Does this perturbation cause a significant change in RP11-334C17.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of RP11-334C17.5. Does this perturbation cause a significant change in RP11-334C17.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4380,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of GALNT7 is measured. Does this perturbation cause a significant change in GALNT7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of GALNT7 is measured. Does this perturbation cause a significant change in GALNT7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4360,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of USP34 is measured. Does this perturbation cause a significant change in USP34 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of USP34 is measured. Does this perturbation cause a significant change in USP34 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4320,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of NOSTRIN is measured. Does this perturbation cause a significant change in NOSTRIN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of NOSTRIN is measured. Does this perturbation cause a significant change in NOSTRIN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of SERPINH1 is measured. Determine whether SERPINH1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of SERPINH1 is measured. Determine whether SERPINH1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of BIRC5. Does perturbing DHDDS lead to a significant change in BIRC5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of BIRC5. Does perturbing DHDDS lead to a significant change in BIRC5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of IL18R1. Does this perturbation cause a significant change in IL18R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of IL18R1. Does this perturbation cause a significant change in IL18R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RP11-685N10.1. Does perturbing MARS lead to a significant change in RP11-685N10.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RP11-685N10.1. Does perturbing MARS lead to a significant change in RP11-685N10.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and CDRT4 expression is quantified. Does this perturbation result in a significant change in CDRT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and CDRT4 expression is quantified. Does this perturbation result in a significant change in CDRT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of HRK. Does this perturbation cause a significant change in HRK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of HRK. Does this perturbation cause a significant change in HRK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1083,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and DDX3X expression is observed. Does this perturbation lead to a significant difference in DDX3X expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and DDX3X expression is observed. Does this perturbation lead to a significant difference in DDX3X expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in RSAD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in RSAD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and DOCK8 expression is quantified. Does this perturbation result in a significant change in DOCK8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and DOCK8 expression is quantified. Does this perturbation result in a significant change in DOCK8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of AC008074.3. Does perturbing CAD lead to a significant change in AC008074.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of AC008074.3. Does perturbing CAD lead to a significant change in AC008074.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and THBS1 expression is quantified. Does this perturbation result in a significant change in THBS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and THBS1 expression is quantified. Does this perturbation result in a significant change in THBS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in ATP2A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in ATP2A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of CD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of CD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2920,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of AC007038.7 is measured. Does this perturbation cause a significant change in AC007038.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of AC007038.7 is measured. Does this perturbation cause a significant change in AC007038.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of CST7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of CST7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of AC007038.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of AC007038.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of AC079466.1 is measured. Determine whether AC079466.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of AC079466.1 is measured. Determine whether AC079466.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and RNF19A expression is measured. Determine whether RNF19A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and RNF19A expression is measured. Determine whether RNF19A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of DOK3 is measured. Determine whether DOK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of DOK3 is measured. Determine whether DOK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and RDH10 expression is measured. Determine whether RDH10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and RDH10 expression is measured. Determine whether RDH10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in RP11-423O2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in RP11-423O2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4590,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of LINC00862 is measured. Does this perturbation cause a significant change in LINC00862 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of LINC00862 is measured. Does this perturbation cause a significant change in LINC00862 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in ITGB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in ITGB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of GPRC5C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of GPRC5C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of RSL24D1 is measured. Determine whether RSL24D1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of RSL24D1 is measured. Determine whether RSL24D1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2610,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of CLDN11 is measured. Does this perturbation cause a significant change in CLDN11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of CLDN11 is measured. Does this perturbation cause a significant change in CLDN11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of MORF4L2 is measured. Determine whether MORF4L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of MORF4L2 is measured. Determine whether MORF4L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of SNRNP25. Does this perturbation cause a significant change in SNRNP25 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of SNRNP25. Does this perturbation cause a significant change in SNRNP25 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and PSMC1 expression is quantified. Does this perturbation result in a significant change in PSMC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and PSMC1 expression is quantified. Does this perturbation result in a significant change in PSMC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and LINC00657 expression is measured. Determine whether LINC00657 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and LINC00657 expression is measured. Determine whether LINC00657 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2793,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and RP11-360L9.8 expression is observed. Does this perturbation lead to a significant difference in RP11-360L9.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and RP11-360L9.8 expression is observed. Does this perturbation lead to a significant difference in RP11-360L9.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in RP11-3D4.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in RP11-3D4.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in KCTD19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in KCTD19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of AC012594.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of AC012594.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of ATP2A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of ATP2A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and F2RL2 expression is quantified. Does this perturbation result in a significant change in F2RL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and F2RL2 expression is quantified. Does this perturbation result in a significant change in F2RL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
598,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor PPP1R16B expression. Decide whether this perturbation leads to a significant alteration in PPP1R16B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor PPP1R16B expression. Decide whether this perturbation leads to a significant alteration in PPP1R16B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and PIK3R1 expression is quantified. Does this perturbation result in a significant change in PIK3R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and PIK3R1 expression is quantified. Does this perturbation result in a significant change in PIK3R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and MYH7B expression is measured. Determine whether MYH7B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and MYH7B expression is measured. Determine whether MYH7B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and CTD-2020K17.1 expression is measured. Determine whether CTD-2020K17.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and CTD-2020K17.1 expression is measured. Determine whether CTD-2020K17.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ARHGAP5. Does perturbing KCTD16 lead to a significant change in ARHGAP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ARHGAP5. Does perturbing KCTD16 lead to a significant change in ARHGAP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of JARID2 is measured. Determine whether JARID2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of JARID2 is measured. Determine whether JARID2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of PITPNB. Does perturbing PTDSS1 lead to a significant change in PITPNB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of PITPNB. Does perturbing PTDSS1 lead to a significant change in PITPNB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2440,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of RP11-119J18.1 is measured. Does this perturbation cause a significant change in RP11-119J18.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of RP11-119J18.1 is measured. Does this perturbation cause a significant change in RP11-119J18.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
638,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor VPS41 expression. Decide whether this perturbation leads to a significant alteration in VPS41 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor VPS41 expression. Decide whether this perturbation leads to a significant alteration in VPS41 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and CTD-2267D19.3 expression is measured. Determine whether CTD-2267D19.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and CTD-2267D19.3 expression is measured. Determine whether CTD-2267D19.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and IL8 expression is quantified. Does this perturbation result in a significant change in IL8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and IL8 expression is quantified. Does this perturbation result in a significant change in IL8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and RP11-146D12.2 expression is measured. Determine whether RP11-146D12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and RP11-146D12.2 expression is measured. Determine whether RP11-146D12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and GPRC5C expression is quantified. Does this perturbation result in a significant change in GPRC5C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and GPRC5C expression is quantified. Does this perturbation result in a significant change in GPRC5C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
898,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor APOL4 expression. Decide whether this perturbation leads to a significant alteration in APOL4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor APOL4 expression. Decide whether this perturbation leads to a significant alteration in APOL4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of DOCK11 is measured. Determine whether DOCK11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of DOCK11 is measured. Determine whether DOCK11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of DNTTIP2. Does perturbing TIMM23 lead to a significant change in DNTTIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of DNTTIP2. Does perturbing TIMM23 lead to a significant change in DNTTIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of RP11-81A22.5. Does this perturbation cause a significant change in RP11-81A22.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of RP11-81A22.5. Does this perturbation cause a significant change in RP11-81A22.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1510,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of TMOD3 is measured. Does this perturbation cause a significant change in TMOD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of TMOD3 is measured. Does this perturbation cause a significant change in TMOD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4118,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor CDCA3 expression. Decide whether this perturbation leads to a significant alteration in CDCA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor CDCA3 expression. Decide whether this perturbation leads to a significant alteration in CDCA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
58,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor C6orf48 expression. Decide whether this perturbation leads to a significant alteration in C6orf48 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor C6orf48 expression. Decide whether this perturbation leads to a significant alteration in C6orf48 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in HM13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in HM13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
94,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RP11-141B14.1. Does this perturbation cause a significant change in RP11-141B14.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RP11-141B14.1. Does this perturbation cause a significant change in RP11-141B14.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2988,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor AC104532.4 expression. Decide whether this perturbation leads to a significant alteration in AC104532.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor AC104532.4 expression. Decide whether this perturbation leads to a significant alteration in AC104532.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1230,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of SRP72 is measured. Does this perturbation cause a significant change in SRP72 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of SRP72 is measured. Does this perturbation cause a significant change in SRP72 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2348,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor C19orf59 expression. Decide whether this perturbation leads to a significant alteration in C19orf59 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor C19orf59 expression. Decide whether this perturbation leads to a significant alteration in C19orf59 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of PTPRC. Does perturbing DDIT3 lead to a significant change in PTPRC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of PTPRC. Does perturbing DDIT3 lead to a significant change in PTPRC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of ASPM is measured. Determine whether ASPM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of ASPM is measured. Determine whether ASPM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3560,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of ZNF292 is measured. Does this perturbation cause a significant change in ZNF292 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of ZNF292 is measured. Does this perturbation cause a significant change in ZNF292 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1053,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and RP11-38P22.2 expression is observed. Does this perturbation lead to a significant difference in RP11-38P22.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and RP11-38P22.2 expression is observed. Does this perturbation lead to a significant difference in RP11-38P22.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1430,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of MARCH8 is measured. Does this perturbation cause a significant change in MARCH8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of MARCH8 is measured. Does this perturbation cause a significant change in MARCH8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of CHD3 is measured. Determine whether CHD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of CHD3 is measured. Determine whether CHD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and AKAP11 expression is measured. Determine whether AKAP11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and AKAP11 expression is measured. Determine whether AKAP11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
578,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor CTD-2001C12.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2001C12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor CTD-2001C12.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2001C12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of GMEB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of GMEB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4470,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of RP11-95O2.5 is measured. Does this perturbation cause a significant change in RP11-95O2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of RP11-95O2.5 is measured. Does this perturbation cause a significant change in RP11-95O2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and CDRT4 expression is measured. Determine whether CDRT4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and CDRT4 expression is measured. Determine whether CDRT4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and NFE2L3 expression is quantified. Does this perturbation result in a significant change in NFE2L3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and NFE2L3 expression is quantified. Does this perturbation result in a significant change in NFE2L3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and HERC2 expression is measured. Determine whether HERC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and HERC2 expression is measured. Determine whether HERC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of APOL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of APOL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and CCDC69 expression is quantified. Does this perturbation result in a significant change in CCDC69 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and CCDC69 expression is quantified. Does this perturbation result in a significant change in CCDC69 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1520,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of ZMYND8 is measured. Does this perturbation cause a significant change in ZMYND8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of ZMYND8 is measured. Does this perturbation cause a significant change in ZMYND8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3188,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor RNF8 expression. Decide whether this perturbation leads to a significant alteration in RNF8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor RNF8 expression. Decide whether this perturbation leads to a significant alteration in RNF8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in PARP11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in PARP11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of LINC01031 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of LINC01031 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in RP11-38P22.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in RP11-38P22.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
843,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of RGS20 is measured. Determine whether RGS20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of RGS20 is measured. Determine whether RGS20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and RNF8 expression is measured. Determine whether RNF8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and RNF8 expression is measured. Determine whether RNF8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of IL32. Does perturbing YIPF5 lead to a significant change in IL32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of IL32. Does perturbing YIPF5 lead to a significant change in IL32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and PLB1 expression is measured. Determine whether PLB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and PLB1 expression is measured. Determine whether PLB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and UBE3A expression is measured. Determine whether UBE3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and UBE3A expression is measured. Determine whether UBE3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2298,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor KLF6 expression. Decide whether this perturbation leads to a significant alteration in KLF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor KLF6 expression. Decide whether this perturbation leads to a significant alteration in KLF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and LINC00938 expression is measured. Determine whether LINC00938 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and LINC00938 expression is measured. Determine whether LINC00938 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2713,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RGS20 expression is observed. Does this perturbation lead to a significant difference in RGS20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RGS20 expression is observed. Does this perturbation lead to a significant difference in RGS20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1038,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor TLN1 expression. Decide whether this perturbation leads to a significant alteration in TLN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor TLN1 expression. Decide whether this perturbation leads to a significant alteration in TLN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of LINC01137. Does perturbing EIF2B3 lead to a significant change in LINC01137 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of LINC01137. Does perturbing EIF2B3 lead to a significant change in LINC01137 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of TTC18 is measured. Determine whether TTC18 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of TTC18 is measured. Determine whether TTC18 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of CENPC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of CENPC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of OR2T6. Does this perturbation cause a significant change in OR2T6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of OR2T6. Does this perturbation cause a significant change in OR2T6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of MED13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of MED13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of DDX6. Does perturbing IER3IP1 lead to a significant change in DDX6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of DDX6. Does perturbing IER3IP1 lead to a significant change in DDX6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of FOXO6. Does perturbing UFM1 lead to a significant change in FOXO6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of FOXO6. Does perturbing UFM1 lead to a significant change in FOXO6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2108,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor PTAR1 expression. Decide whether this perturbation leads to a significant alteration in PTAR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor PTAR1 expression. Decide whether this perturbation leads to a significant alteration in PTAR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of CD58 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of CD58 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of HIST1H2AM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of HIST1H2AM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4440,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of CTBS is measured. Does this perturbation cause a significant change in CTBS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of CTBS is measured. Does this perturbation cause a significant change in CTBS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of POLR2J3. Does this perturbation cause a significant change in POLR2J3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of POLR2J3. Does this perturbation cause a significant change in POLR2J3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1678,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor AC012594.1 expression. Decide whether this perturbation leads to a significant alteration in AC012594.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor AC012594.1 expression. Decide whether this perturbation leads to a significant alteration in AC012594.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of OBSCN is measured. Determine whether OBSCN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of OBSCN is measured. Determine whether OBSCN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of MT2A. Does perturbing ARHGAP22 lead to a significant change in MT2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of MT2A. Does perturbing ARHGAP22 lead to a significant change in MT2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of RP11-322J23.1 is measured. Determine whether RP11-322J23.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of RP11-322J23.1 is measured. Determine whether RP11-322J23.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
158,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor CTSF expression. Decide whether this perturbation leads to a significant alteration in CTSF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor CTSF expression. Decide whether this perturbation leads to a significant alteration in CTSF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in EXOC3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in EXOC3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3523,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and TSPAN33 expression is observed. Does this perturbation lead to a significant difference in TSPAN33 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and TSPAN33 expression is observed. Does this perturbation lead to a significant difference in TSPAN33 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of RP11-328J2.1. Does this perturbation cause a significant change in RP11-328J2.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of RP11-328J2.1. Does this perturbation cause a significant change in RP11-328J2.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of SNRNP25 is measured. Determine whether SNRNP25 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of SNRNP25 is measured. Determine whether SNRNP25 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of EP400 is measured. Determine whether EP400 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of EP400 is measured. Determine whether EP400 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and VIM-AS1 expression is quantified. Does this perturbation result in a significant change in VIM-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and VIM-AS1 expression is quantified. Does this perturbation result in a significant change in VIM-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
87,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of PHF3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of PHF3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of SPEN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of SPEN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in AC018878.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in AC018878.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of EBI3. Does this perturbation cause a significant change in EBI3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of EBI3. Does this perturbation cause a significant change in EBI3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of S100A10. Does this perturbation cause a significant change in S100A10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of S100A10. Does this perturbation cause a significant change in S100A10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of GUSB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of GUSB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of TMEM60 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of TMEM60 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4138,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor WDR72 expression. Decide whether this perturbation leads to a significant alteration in WDR72 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor WDR72 expression. Decide whether this perturbation leads to a significant alteration in WDR72 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of PPP4R2. Does perturbing HSPA9 lead to a significant change in PPP4R2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of PPP4R2. Does perturbing HSPA9 lead to a significant change in PPP4R2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3670,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of ZC3H7A is measured. Does this perturbation cause a significant change in ZC3H7A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of ZC3H7A is measured. Does this perturbation cause a significant change in ZC3H7A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1528,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor ZMYND8 expression. Decide whether this perturbation leads to a significant alteration in ZMYND8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor ZMYND8 expression. Decide whether this perturbation leads to a significant alteration in ZMYND8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in CD58 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in CD58 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of CD58 is measured. Determine whether CD58 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of CD58 is measured. Determine whether CD58 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of RP11-640M9.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of RP11-640M9.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of C6orf120. Does perturbing NEDD8 lead to a significant change in C6orf120 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of C6orf120. Does perturbing NEDD8 lead to a significant change in C6orf120 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of LTN1 is measured. Determine whether LTN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of LTN1 is measured. Determine whether LTN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3690,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of TTC18 is measured. Does this perturbation cause a significant change in TTC18 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of TTC18 is measured. Does this perturbation cause a significant change in TTC18 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1303,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and ITGB2 expression is observed. Does this perturbation lead to a significant difference in ITGB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and ITGB2 expression is observed. Does this perturbation lead to a significant difference in ITGB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of TKTL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of TKTL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of HIST1H2BC. Does perturbing DNAJC19 lead to a significant change in HIST1H2BC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of HIST1H2BC. Does perturbing DNAJC19 lead to a significant change in HIST1H2BC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1258,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor IL8 expression. Decide whether this perturbation leads to a significant alteration in IL8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor IL8 expression. Decide whether this perturbation leads to a significant alteration in IL8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and PSMC1 expression is measured. Determine whether PSMC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and PSMC1 expression is measured. Determine whether PSMC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3943,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ROBO1 expression is observed. Does this perturbation lead to a significant difference in ROBO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ROBO1 expression is observed. Does this perturbation lead to a significant difference in ROBO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and RSAD2 expression is quantified. Does this perturbation result in a significant change in RSAD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and RSAD2 expression is quantified. Does this perturbation result in a significant change in RSAD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4423,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and RP11-157D23.2 expression is observed. Does this perturbation lead to a significant difference in RP11-157D23.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and RP11-157D23.2 expression is observed. Does this perturbation lead to a significant difference in RP11-157D23.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and NINJ2 expression is quantified. Does this perturbation result in a significant change in NINJ2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and NINJ2 expression is quantified. Does this perturbation result in a significant change in NINJ2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3100,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PSMD14 is measured. Does this perturbation cause a significant change in PSMD14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PSMD14 is measured. Does this perturbation cause a significant change in PSMD14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2790,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of RP11-360L9.8 is measured. Does this perturbation cause a significant change in RP11-360L9.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of RP11-360L9.8 is measured. Does this perturbation cause a significant change in RP11-360L9.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of RP11-38P22.2. Does perturbing IARS2 lead to a significant change in RP11-38P22.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of RP11-38P22.2. Does perturbing IARS2 lead to a significant change in RP11-38P22.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
418,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor SPINK5 expression. Decide whether this perturbation leads to a significant alteration in SPINK5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor SPINK5 expression. Decide whether this perturbation leads to a significant alteration in SPINK5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and SNHG7 expression is quantified. Does this perturbation result in a significant change in SNHG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and SNHG7 expression is quantified. Does this perturbation result in a significant change in SNHG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of HMGCS1. Does perturbing EIF2B4 lead to a significant change in HMGCS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of HMGCS1. Does perturbing EIF2B4 lead to a significant change in HMGCS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1110,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of GOT1 is measured. Does this perturbation cause a significant change in GOT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of GOT1 is measured. Does this perturbation cause a significant change in GOT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and COPB1 expression is measured. Determine whether COPB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and COPB1 expression is measured. Determine whether COPB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3668,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor EP400 expression. Decide whether this perturbation leads to a significant alteration in EP400 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor EP400 expression. Decide whether this perturbation leads to a significant alteration in EP400 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1613,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and RP11-81A22.5 expression is observed. Does this perturbation lead to a significant difference in RP11-81A22.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and RP11-81A22.5 expression is observed. Does this perturbation lead to a significant difference in RP11-81A22.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of OBSCN. Does this perturbation cause a significant change in OBSCN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of OBSCN. Does this perturbation cause a significant change in OBSCN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2323,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and H3F3B expression is observed. Does this perturbation lead to a significant difference in H3F3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and H3F3B expression is observed. Does this perturbation lead to a significant difference in H3F3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of ZNF292 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of ZNF292 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of CLDN11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of CLDN11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of RBM12B-AS1. Does perturbing GBF1 lead to a significant change in RBM12B-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of RBM12B-AS1. Does perturbing GBF1 lead to a significant change in RBM12B-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and FAM114A1 expression is quantified. Does this perturbation result in a significant change in FAM114A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and FAM114A1 expression is quantified. Does this perturbation result in a significant change in FAM114A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in CTD-2521M24.9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in CTD-2521M24.9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of TRAPPC10. Does perturbing GMPPB lead to a significant change in TRAPPC10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of TRAPPC10. Does perturbing GMPPB lead to a significant change in TRAPPC10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of AC015987.1 is measured. Determine whether AC015987.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of AC015987.1 is measured. Determine whether AC015987.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
52,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and C6orf48 expression is quantified. Does this perturbation result in a significant change in C6orf48 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and C6orf48 expression is quantified. Does this perturbation result in a significant change in C6orf48 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of MLEC. Does perturbing ARHGAP22 lead to a significant change in MLEC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of MLEC. Does perturbing ARHGAP22 lead to a significant change in MLEC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3053,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and RP11-363D14.1 expression is observed. Does this perturbation lead to a significant difference in RP11-363D14.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and RP11-363D14.1 expression is observed. Does this perturbation lead to a significant difference in RP11-363D14.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of CD9 is measured. Determine whether CD9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of CD9 is measured. Determine whether CD9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of CDRT4 is measured. Determine whether CDRT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of CDRT4 is measured. Determine whether CDRT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
783,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and WHAMM expression is observed. Does this perturbation lead to a significant difference in WHAMM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and WHAMM expression is observed. Does this perturbation lead to a significant difference in WHAMM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and KCNH7 expression is measured. Determine whether KCNH7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and KCNH7 expression is measured. Determine whether KCNH7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of TRIM24 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of TRIM24 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of HOTAIRM1. Does perturbing QARS lead to a significant change in HOTAIRM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of HOTAIRM1. Does perturbing QARS lead to a significant change in HOTAIRM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and RP11-640M9.1 expression is quantified. Does this perturbation result in a significant change in RP11-640M9.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and RP11-640M9.1 expression is quantified. Does this perturbation result in a significant change in RP11-640M9.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
560,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of IL32 is measured. Does this perturbation cause a significant change in IL32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of IL32 is measured. Does this perturbation cause a significant change in IL32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
243,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and UHRF1BP1L expression is observed. Does this perturbation lead to a significant difference in UHRF1BP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and UHRF1BP1L expression is observed. Does this perturbation lead to a significant difference in UHRF1BP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of MTPN is measured. Determine whether MTPN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of MTPN is measured. Determine whether MTPN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3798,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor POLR2J3 expression. Decide whether this perturbation leads to a significant alteration in POLR2J3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor POLR2J3 expression. Decide whether this perturbation leads to a significant alteration in POLR2J3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and LAMP2 expression is quantified. Does this perturbation result in a significant change in LAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and LAMP2 expression is quantified. Does this perturbation result in a significant change in LAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of BAMBI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of BAMBI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2443,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and RP11-119J18.1 expression is observed. Does this perturbation lead to a significant difference in RP11-119J18.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and RP11-119J18.1 expression is observed. Does this perturbation lead to a significant difference in RP11-119J18.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of WHSC1 is measured. Determine whether WHSC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of WHSC1 is measured. Determine whether WHSC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and IFT27 expression is measured. Determine whether IFT27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and IFT27 expression is measured. Determine whether IFT27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of ARHGAP11A. Does this perturbation cause a significant change in ARHGAP11A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of ARHGAP11A. Does this perturbation cause a significant change in ARHGAP11A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of CYP17A1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of CYP17A1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and PDE9A expression is measured. Determine whether PDE9A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and PDE9A expression is measured. Determine whether PDE9A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in TSNAXIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in TSNAXIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1280,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of ZNF280B is measured. Does this perturbation cause a significant change in ZNF280B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of ZNF280B is measured. Does this perturbation cause a significant change in ZNF280B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5088,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor GPR146 expression. Decide whether this perturbation leads to a significant alteration in GPR146 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor GPR146 expression. Decide whether this perturbation leads to a significant alteration in GPR146 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and YTHDF2 expression is measured. Determine whether YTHDF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and YTHDF2 expression is measured. Determine whether YTHDF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of CTNNB1. Does perturbing MRPL39 lead to a significant change in CTNNB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of CTNNB1. Does perturbing MRPL39 lead to a significant change in CTNNB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4088,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor SPEN expression. Decide whether this perturbation leads to a significant alteration in SPEN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor SPEN expression. Decide whether this perturbation leads to a significant alteration in SPEN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and FYTTD1 expression is measured. Determine whether FYTTD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and FYTTD1 expression is measured. Determine whether FYTTD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and HIST1H2AM expression is measured. Determine whether HIST1H2AM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and HIST1H2AM expression is measured. Determine whether HIST1H2AM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in CTBS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in CTBS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1193,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and RP11-435O5.4 expression is observed. Does this perturbation lead to a significant difference in RP11-435O5.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and RP11-435O5.4 expression is observed. Does this perturbation lead to a significant difference in RP11-435O5.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of KIF4A. Does this perturbation cause a significant change in KIF4A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of KIF4A. Does this perturbation cause a significant change in KIF4A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3020,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of HIST1H2AC is measured. Does this perturbation cause a significant change in HIST1H2AC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of HIST1H2AC is measured. Does this perturbation cause a significant change in HIST1H2AC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of ATF6. Does perturbing AMIGO3 lead to a significant change in ATF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of ATF6. Does perturbing AMIGO3 lead to a significant change in ATF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of HIST1H2AM. Does perturbing MRPL39 lead to a significant change in HIST1H2AM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of HIST1H2AM. Does perturbing MRPL39 lead to a significant change in HIST1H2AM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of RP11-146D12.2 is measured. Determine whether RP11-146D12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of RP11-146D12.2 is measured. Determine whether RP11-146D12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in VIMP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in VIMP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of LTBP1. Does perturbing GMPPB lead to a significant change in LTBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of LTBP1. Does perturbing GMPPB lead to a significant change in LTBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1218,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor JARID2 expression. Decide whether this perturbation leads to a significant alteration in JARID2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor JARID2 expression. Decide whether this perturbation leads to a significant alteration in JARID2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of ZNF429. Does perturbing CREB1 lead to a significant change in ZNF429 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of ZNF429. Does perturbing CREB1 lead to a significant change in ZNF429 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1358,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor TAGLN expression. Decide whether this perturbation leads to a significant alteration in TAGLN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor TAGLN expression. Decide whether this perturbation leads to a significant alteration in TAGLN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1480,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of WHSC1 is measured. Does this perturbation cause a significant change in WHSC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of WHSC1 is measured. Does this perturbation cause a significant change in WHSC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of SERPING1. Does this perturbation cause a significant change in SERPING1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of SERPING1. Does this perturbation cause a significant change in SERPING1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3883,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and RP11-573D15.2 expression is observed. Does this perturbation lead to a significant difference in RP11-573D15.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and RP11-573D15.2 expression is observed. Does this perturbation lead to a significant difference in RP11-573D15.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3870,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of C9orf64 is measured. Does this perturbation cause a significant change in C9orf64 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of C9orf64 is measured. Does this perturbation cause a significant change in C9orf64 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in SNHG10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in SNHG10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3663,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and EP400 expression is observed. Does this perturbation lead to a significant difference in EP400 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and EP400 expression is observed. Does this perturbation lead to a significant difference in EP400 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of THBS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of THBS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4530,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of RP11-304M2.5 is measured. Does this perturbation cause a significant change in RP11-304M2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of RP11-304M2.5 is measured. Does this perturbation cause a significant change in RP11-304M2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and RCBTB2 expression is measured. Determine whether RCBTB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and RCBTB2 expression is measured. Determine whether RCBTB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and TMEM60 expression is quantified. Does this perturbation result in a significant change in TMEM60 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and TMEM60 expression is quantified. Does this perturbation result in a significant change in TMEM60 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of NAV2. Does perturbing CARS lead to a significant change in NAV2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of NAV2. Does perturbing CARS lead to a significant change in NAV2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of LINC01137. Does this perturbation cause a significant change in LINC01137 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of LINC01137. Does this perturbation cause a significant change in LINC01137 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in TNFRSF10B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in TNFRSF10B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4930,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of ATXN7L3B is measured. Does this perturbation cause a significant change in ATXN7L3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of ATXN7L3B is measured. Does this perturbation cause a significant change in ATXN7L3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of ABI2. Does perturbing GNPNAT1 lead to a significant change in ABI2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of ABI2. Does perturbing GNPNAT1 lead to a significant change in ABI2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of MARCH8 is measured. Determine whether MARCH8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of MARCH8 is measured. Determine whether MARCH8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1793,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and PKDCC expression is observed. Does this perturbation lead to a significant difference in PKDCC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and PKDCC expression is observed. Does this perturbation lead to a significant difference in PKDCC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1473,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and ARHGAP30 expression is observed. Does this perturbation lead to a significant difference in ARHGAP30 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and ARHGAP30 expression is observed. Does this perturbation lead to a significant difference in ARHGAP30 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of CENPC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of CENPC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of ROCK1 is measured. Determine whether ROCK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of ROCK1 is measured. Determine whether ROCK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and DST expression is measured. Determine whether DST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and DST expression is measured. Determine whether DST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of VIMP is measured. Determine whether VIMP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of VIMP is measured. Determine whether VIMP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of ATP5EP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of ATP5EP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of TRIM38. Does this perturbation cause a significant change in TRIM38 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of TRIM38. Does this perturbation cause a significant change in TRIM38 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of MYH7B is measured. Determine whether MYH7B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of MYH7B is measured. Determine whether MYH7B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4940,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of RGS20 is measured. Does this perturbation cause a significant change in RGS20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of RGS20 is measured. Does this perturbation cause a significant change in RGS20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2628,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor MORF4L2 expression. Decide whether this perturbation leads to a significant alteration in MORF4L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor MORF4L2 expression. Decide whether this perturbation leads to a significant alteration in MORF4L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of SERPINF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of SERPINF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of AC104532.4. Does this perturbation cause a significant change in AC104532.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of AC104532.4. Does this perturbation cause a significant change in AC104532.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
413,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and SPINK5 expression is observed. Does this perturbation lead to a significant difference in SPINK5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and SPINK5 expression is observed. Does this perturbation lead to a significant difference in SPINK5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and VPS41 expression is quantified. Does this perturbation result in a significant change in VPS41 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and VPS41 expression is quantified. Does this perturbation result in a significant change in VPS41 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1548,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor CTD-2267D19.3 expression. Decide whether this perturbation leads to a significant alteration in CTD-2267D19.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor CTD-2267D19.3 expression. Decide whether this perturbation leads to a significant alteration in CTD-2267D19.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3113,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and NXF1 expression is observed. Does this perturbation lead to a significant difference in NXF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and NXF1 expression is observed. Does this perturbation lead to a significant difference in NXF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of CTD-2587M2.1. Does perturbing CAD lead to a significant change in CTD-2587M2.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of CTD-2587M2.1. Does perturbing CAD lead to a significant change in CTD-2587M2.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of PAK1IP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of PAK1IP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and NUFIP2 expression is measured. Determine whether NUFIP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and NUFIP2 expression is measured. Determine whether NUFIP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1683,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and EP300 expression is observed. Does this perturbation lead to a significant difference in EP300 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and EP300 expression is observed. Does this perturbation lead to a significant difference in EP300 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2120,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of SEC23IP. Does this perturbation cause a significant change in SEC23IP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of SEC23IP. Does this perturbation cause a significant change in SEC23IP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3708,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor PARP11 expression. Decide whether this perturbation leads to a significant alteration in PARP11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor PARP11 expression. Decide whether this perturbation leads to a significant alteration in PARP11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and CST7 expression is quantified. Does this perturbation result in a significant change in CST7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and CST7 expression is quantified. Does this perturbation result in a significant change in CST7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of GSN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of GSN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of C10orf32. Does this perturbation cause a significant change in C10orf32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of C10orf32. Does this perturbation cause a significant change in C10orf32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2850,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of OXLD1 is measured. Does this perturbation cause a significant change in OXLD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of OXLD1 is measured. Does this perturbation cause a significant change in OXLD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1878,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor AC096559.1 expression. Decide whether this perturbation leads to a significant alteration in AC096559.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor AC096559.1 expression. Decide whether this perturbation leads to a significant alteration in AC096559.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of HIST1H1D. Does this perturbation cause a significant change in HIST1H1D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of HIST1H1D. Does this perturbation cause a significant change in HIST1H1D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of UHMK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of UHMK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of AC005540.3. Does perturbing FECH lead to a significant change in AC005540.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of AC005540.3. Does perturbing FECH lead to a significant change in AC005540.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and RP11-573D15.9 expression is measured. Determine whether RP11-573D15.9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and RP11-573D15.9 expression is measured. Determine whether RP11-573D15.9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and OPTN expression is measured. Determine whether OPTN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and OPTN expression is measured. Determine whether OPTN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4250,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of PAK1IP1 is measured. Does this perturbation cause a significant change in PAK1IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of PAK1IP1 is measured. Does this perturbation cause a significant change in PAK1IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4898,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor KIAA1731 expression. Decide whether this perturbation leads to a significant alteration in KIAA1731 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor KIAA1731 expression. Decide whether this perturbation leads to a significant alteration in KIAA1731 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in ZNF341 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in ZNF341 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of BRWD3 is measured. Determine whether BRWD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of BRWD3 is measured. Determine whether BRWD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and DUT expression is quantified. Does this perturbation result in a significant change in DUT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and DUT expression is quantified. Does this perturbation result in a significant change in DUT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and RP11-242O24.5 expression is measured. Determine whether RP11-242O24.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and RP11-242O24.5 expression is measured. Determine whether RP11-242O24.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
96,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RP11-141B14.1 is measured. Determine whether RP11-141B14.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RP11-141B14.1 is measured. Determine whether RP11-141B14.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
913,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and HIST1H3D expression is observed. Does this perturbation lead to a significant difference in HIST1H3D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and HIST1H3D expression is observed. Does this perturbation lead to a significant difference in HIST1H3D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of IRF7. Does perturbing IER3IP1 lead to a significant change in IRF7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of IRF7. Does perturbing IER3IP1 lead to a significant change in IRF7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of HIST1H2AM is measured. Determine whether HIST1H2AM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of HIST1H2AM is measured. Determine whether HIST1H2AM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and CELF6 expression is measured. Determine whether CELF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and CELF6 expression is measured. Determine whether CELF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3083,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and TROAP expression is observed. Does this perturbation lead to a significant difference in TROAP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and TROAP expression is observed. Does this perturbation lead to a significant difference in TROAP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of QSER1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of QSER1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of RP11-3D4.3. Does perturbing EIF2S1 lead to a significant change in RP11-3D4.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of RP11-3D4.3. Does perturbing EIF2S1 lead to a significant change in RP11-3D4.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and RP11-212I21.4 expression is measured. Determine whether RP11-212I21.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and RP11-212I21.4 expression is measured. Determine whether RP11-212I21.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of OR2T6. Does perturbing GMPPB lead to a significant change in OR2T6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of OR2T6. Does perturbing GMPPB lead to a significant change in OR2T6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and ATP5EP2 expression is quantified. Does this perturbation result in a significant change in ATP5EP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and ATP5EP2 expression is quantified. Does this perturbation result in a significant change in ATP5EP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4668,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor LINC01137 expression. Decide whether this perturbation leads to a significant alteration in LINC01137 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor LINC01137 expression. Decide whether this perturbation leads to a significant alteration in LINC01137 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of CENPF. Does perturbing CCND3 lead to a significant change in CENPF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of CENPF. Does perturbing CCND3 lead to a significant change in CENPF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1720,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of VIM-AS1 is measured. Does this perturbation cause a significant change in VIM-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of VIM-AS1 is measured. Does this perturbation cause a significant change in VIM-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of WHAMM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of WHAMM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3210,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of TTC32 is measured. Does this perturbation cause a significant change in TTC32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of TTC32 is measured. Does this perturbation cause a significant change in TTC32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in HIST1H2AM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in HIST1H2AM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2388,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor DKFZP779L1853 expression. Decide whether this perturbation leads to a significant alteration in DKFZP779L1853 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor DKFZP779L1853 expression. Decide whether this perturbation leads to a significant alteration in DKFZP779L1853 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4223,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and IFT27 expression is observed. Does this perturbation lead to a significant difference in IFT27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and IFT27 expression is observed. Does this perturbation lead to a significant difference in IFT27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of NBEAL2 is measured. Determine whether NBEAL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of NBEAL2 is measured. Determine whether NBEAL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and ARHGAP6 expression is measured. Determine whether ARHGAP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and ARHGAP6 expression is measured. Determine whether ARHGAP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of RP11-38P22.2. Does this perturbation cause a significant change in RP11-38P22.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of RP11-38P22.2. Does this perturbation cause a significant change in RP11-38P22.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and TET1 expression is quantified. Does this perturbation result in a significant change in TET1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and TET1 expression is quantified. Does this perturbation result in a significant change in TET1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of LST1. Does perturbing DNAJC19 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of LST1. Does perturbing DNAJC19 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in MLEC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in MLEC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of CCDC69 is measured. Determine whether CCDC69 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of CCDC69 is measured. Determine whether CCDC69 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of PPM1N. Does this perturbation cause a significant change in PPM1N expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of PPM1N. Does this perturbation cause a significant change in PPM1N expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of RTN2. Does perturbing TTI2 lead to a significant change in RTN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of RTN2. Does perturbing TTI2 lead to a significant change in RTN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in PPM1N expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in PPM1N expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and ZEB1 expression is measured. Determine whether ZEB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and ZEB1 expression is measured. Determine whether ZEB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of GOT1. Does perturbing SOCS1 lead to a significant change in GOT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of GOT1. Does perturbing SOCS1 lead to a significant change in GOT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in RAD51AP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in RAD51AP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1410,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of NOXA1 is measured. Does this perturbation cause a significant change in NOXA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of NOXA1 is measured. Does this perturbation cause a significant change in NOXA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of ATF7IP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of ATF7IP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of CTD-2001C12.1. Does this perturbation cause a significant change in CTD-2001C12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of CTD-2001C12.1. Does this perturbation cause a significant change in CTD-2001C12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3760,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of RNF19A is measured. Does this perturbation cause a significant change in RNF19A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of RNF19A is measured. Does this perturbation cause a significant change in RNF19A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3873,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and C9orf64 expression is observed. Does this perturbation lead to a significant difference in C9orf64 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and C9orf64 expression is observed. Does this perturbation lead to a significant difference in C9orf64 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in C17orf64 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in C17orf64 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of NOX5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of NOX5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of ABI2 is measured. Determine whether ABI2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of ABI2 is measured. Determine whether ABI2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2730,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of CTD-2587M2.1 is measured. Determine whether CTD-2587M2.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of CTD-2587M2.1 is measured. Determine whether CTD-2587M2.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of PIK3IP1. Does this perturbation cause a significant change in PIK3IP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of PIK3IP1. Does this perturbation cause a significant change in PIK3IP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of SMIM14. Does perturbing PSMD4 lead to a significant change in SMIM14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of SMIM14. Does perturbing PSMD4 lead to a significant change in SMIM14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of RP11-16E12.1. Does this perturbation cause a significant change in RP11-16E12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of RP11-16E12.1. Does this perturbation cause a significant change in RP11-16E12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2080,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of PGM3 is measured. Does this perturbation cause a significant change in PGM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of PGM3 is measured. Does this perturbation cause a significant change in PGM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of RP11-90P5.2 is measured. Determine whether RP11-90P5.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of RP11-90P5.2 is measured. Determine whether RP11-90P5.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3300,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of SMIM14 is measured. Does this perturbation cause a significant change in SMIM14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of SMIM14 is measured. Does this perturbation cause a significant change in SMIM14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of HLA-E. Does perturbing HSPA5 lead to a significant change in HLA-E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of HLA-E. Does perturbing HSPA5 lead to a significant change in HLA-E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4483,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and PPP1R16B expression is observed. Does this perturbation lead to a significant difference in PPP1R16B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and PPP1R16B expression is observed. Does this perturbation lead to a significant difference in PPP1R16B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and IDS expression is quantified. Does this perturbation result in a significant change in IDS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and IDS expression is quantified. Does this perturbation result in a significant change in IDS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in CTD-2001C12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in CTD-2001C12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of S100A13 is measured. Determine whether S100A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of S100A13 is measured. Determine whether S100A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
500,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of PTPN11 is measured. Does this perturbation cause a significant change in PTPN11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of PTPN11 is measured. Does this perturbation cause a significant change in PTPN11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in TRAPPC10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in TRAPPC10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3410,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of NOX5 is measured. Does this perturbation cause a significant change in NOX5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of NOX5 is measured. Does this perturbation cause a significant change in NOX5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
470,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of RP11-146D12.2 is measured. Does this perturbation cause a significant change in RP11-146D12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of RP11-146D12.2 is measured. Does this perturbation cause a significant change in RP11-146D12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4800,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of EIF3A is measured. Does this perturbation cause a significant change in EIF3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of EIF3A is measured. Does this perturbation cause a significant change in EIF3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and WDR72 expression is measured. Determine whether WDR72 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and WDR72 expression is measured. Determine whether WDR72 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and RP11-838N2.4 expression is measured. Determine whether RP11-838N2.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and RP11-838N2.4 expression is measured. Determine whether RP11-838N2.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of PTPRC. Does this perturbation cause a significant change in PTPRC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of PTPRC. Does this perturbation cause a significant change in PTPRC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of GNPTG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of GNPTG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of FAM114A1. Does this perturbation cause a significant change in FAM114A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of FAM114A1. Does this perturbation cause a significant change in FAM114A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and GUSB expression is measured. Determine whether GUSB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and GUSB expression is measured. Determine whether GUSB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2243,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and AMOTL1 expression is observed. Does this perturbation lead to a significant difference in AMOTL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and AMOTL1 expression is observed. Does this perturbation lead to a significant difference in AMOTL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in QSER1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in QSER1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and EP300 expression is measured. Determine whether EP300 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and EP300 expression is measured. Determine whether EP300 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in CASP8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in CASP8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1650,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of EBI3 is measured. Does this perturbation cause a significant change in EBI3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of EBI3 is measured. Does this perturbation cause a significant change in EBI3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of RIMS3. Does perturbing BHLHE40 lead to a significant change in RIMS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of RIMS3. Does perturbing BHLHE40 lead to a significant change in RIMS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3613,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and TIPARP expression is observed. Does this perturbation lead to a significant difference in TIPARP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and TIPARP expression is observed. Does this perturbation lead to a significant difference in TIPARP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and HLA-E expression is quantified. Does this perturbation result in a significant change in HLA-E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and HLA-E expression is quantified. Does this perturbation result in a significant change in HLA-E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
54,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of C6orf48. Does this perturbation cause a significant change in C6orf48 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of C6orf48. Does this perturbation cause a significant change in C6orf48 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in FCGRT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in FCGRT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of SNHG10. Does perturbing QARS lead to a significant change in SNHG10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of SNHG10. Does perturbing QARS lead to a significant change in SNHG10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and TMEM87B expression is quantified. Does this perturbation result in a significant change in TMEM87B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and TMEM87B expression is quantified. Does this perturbation result in a significant change in TMEM87B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4948,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor RGS20 expression. Decide whether this perturbation leads to a significant alteration in RGS20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor RGS20 expression. Decide whether this perturbation leads to a significant alteration in RGS20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of RP1-274L7.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of RP1-274L7.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1340,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of NSD1 is measured. Does this perturbation cause a significant change in NSD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of NSD1 is measured. Does this perturbation cause a significant change in NSD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in CFH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in CFH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of PCK2. Does perturbing EIF2B2 lead to a significant change in PCK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of PCK2. Does perturbing EIF2B2 lead to a significant change in PCK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4078,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor RP1-274L7.1 expression. Decide whether this perturbation leads to a significant alteration in RP1-274L7.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor RP1-274L7.1 expression. Decide whether this perturbation leads to a significant alteration in RP1-274L7.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1628,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor ATP6AP2 expression. Decide whether this perturbation leads to a significant alteration in ATP6AP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor ATP6AP2 expression. Decide whether this perturbation leads to a significant alteration in ATP6AP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4310,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of MED13 is measured. Does this perturbation cause a significant change in MED13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of MED13 is measured. Does this perturbation cause a significant change in MED13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and ATF7IP2 expression is quantified. Does this perturbation result in a significant change in ATF7IP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and ATF7IP2 expression is quantified. Does this perturbation result in a significant change in ATF7IP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3418,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor NOX5 expression. Decide whether this perturbation leads to a significant alteration in NOX5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor NOX5 expression. Decide whether this perturbation leads to a significant alteration in NOX5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of REST. Does perturbing TIMM23 lead to a significant change in REST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of REST. Does perturbing TIMM23 lead to a significant change in REST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and EPS15 expression is quantified. Does this perturbation result in a significant change in EPS15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and EPS15 expression is quantified. Does this perturbation result in a significant change in EPS15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2503,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and UFD1L expression is observed. Does this perturbation lead to a significant difference in UFD1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and UFD1L expression is observed. Does this perturbation lead to a significant difference in UFD1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4143,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and RILPL2 expression is observed. Does this perturbation lead to a significant difference in RILPL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and RILPL2 expression is observed. Does this perturbation lead to a significant difference in RILPL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of MYH7B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of MYH7B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1223,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and UBE3A expression is observed. Does this perturbation lead to a significant difference in UBE3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and UBE3A expression is observed. Does this perturbation lead to a significant difference in UBE3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of TIPARP. Does this perturbation cause a significant change in TIPARP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of TIPARP. Does this perturbation cause a significant change in TIPARP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and GRN expression is quantified. Does this perturbation result in a significant change in GRN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and GRN expression is quantified. Does this perturbation result in a significant change in GRN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of C12orf44. Does this perturbation cause a significant change in C12orf44 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of C12orf44. Does this perturbation cause a significant change in C12orf44 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in UQCRB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in UQCRB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2848,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor SPAST expression. Decide whether this perturbation leads to a significant alteration in SPAST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor SPAST expression. Decide whether this perturbation leads to a significant alteration in SPAST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1968,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor ARHGDIB expression. Decide whether this perturbation leads to a significant alteration in ARHGDIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor ARHGDIB expression. Decide whether this perturbation leads to a significant alteration in ARHGDIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of ERP29 is measured. Determine whether ERP29 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of ERP29 is measured. Determine whether ERP29 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of AC079466.1. Does perturbing MRGBP lead to a significant change in AC079466.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of AC079466.1. Does perturbing MRGBP lead to a significant change in AC079466.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and PTPRC expression is quantified. Does this perturbation result in a significant change in PTPRC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and PTPRC expression is quantified. Does this perturbation result in a significant change in PTPRC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of GCKR is measured. Determine whether GCKR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of GCKR is measured. Determine whether GCKR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and CD46 expression is measured. Determine whether CD46 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and CD46 expression is measured. Determine whether CD46 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3350,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of EXOC3L2 is measured. Does this perturbation cause a significant change in EXOC3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of EXOC3L2 is measured. Does this perturbation cause a significant change in EXOC3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2768,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor CDK13 expression. Decide whether this perturbation leads to a significant alteration in CDK13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor CDK13 expression. Decide whether this perturbation leads to a significant alteration in CDK13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and CRNDE expression is measured. Determine whether CRNDE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and CRNDE expression is measured. Determine whether CRNDE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2230,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of FAM212A is measured. Does this perturbation cause a significant change in FAM212A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of FAM212A is measured. Does this perturbation cause a significant change in FAM212A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of RP11-573D15.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of RP11-573D15.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of PELO is measured. Determine whether PELO shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of PELO is measured. Determine whether PELO shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of PDK2. Does perturbing DERL2 lead to a significant change in PDK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of PDK2. Does perturbing DERL2 lead to a significant change in PDK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
56,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of C6orf48 is measured. Determine whether C6orf48 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of C6orf48 is measured. Determine whether C6orf48 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of ARHGAP6 is measured. Determine whether ARHGAP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of ARHGAP6 is measured. Determine whether ARHGAP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4020,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of PIK3R3 is measured. Does this perturbation cause a significant change in PIK3R3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of PIK3R3 is measured. Does this perturbation cause a significant change in PIK3R3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of PELO. Does this perturbation cause a significant change in PELO expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of PELO. Does this perturbation cause a significant change in PELO expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
39,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and CASP4 expression is measured. Determine whether CASP4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and CASP4 expression is measured. Determine whether CASP4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of STC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of STC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of CTSF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of CTSF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in JARID2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in JARID2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2508,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor UFD1L expression. Decide whether this perturbation leads to a significant alteration in UFD1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor UFD1L expression. Decide whether this perturbation leads to a significant alteration in UFD1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and TLN1 expression is measured. Determine whether TLN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and TLN1 expression is measured. Determine whether TLN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of RP11-138C9.1 is measured. Determine whether RP11-138C9.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of RP11-138C9.1 is measured. Determine whether RP11-138C9.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of SBF2. Does perturbing FARSB lead to a significant change in SBF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of SBF2. Does perturbing FARSB lead to a significant change in SBF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3518,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor TMEM60 expression. Decide whether this perturbation leads to a significant alteration in TMEM60 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor TMEM60 expression. Decide whether this perturbation leads to a significant alteration in TMEM60 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in DNASE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in DNASE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4208,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor IL18R1 expression. Decide whether this perturbation leads to a significant alteration in IL18R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor IL18R1 expression. Decide whether this perturbation leads to a significant alteration in IL18R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and ARHGAP30 expression is quantified. Does this perturbation result in a significant change in ARHGAP30 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and ARHGAP30 expression is quantified. Does this perturbation result in a significant change in ARHGAP30 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of RP13-216E22.4. Does this perturbation cause a significant change in RP13-216E22.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of RP13-216E22.4. Does this perturbation cause a significant change in RP13-216E22.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3498,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor DST expression. Decide whether this perturbation leads to a significant alteration in DST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor DST expression. Decide whether this perturbation leads to a significant alteration in DST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4793,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and ANPEP expression is observed. Does this perturbation lead to a significant difference in ANPEP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and ANPEP expression is observed. Does this perturbation lead to a significant difference in ANPEP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4760,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of TLK2 is measured. Does this perturbation cause a significant change in TLK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of TLK2 is measured. Does this perturbation cause a significant change in TLK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in SLC37A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in SLC37A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4718,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor TAP1 expression. Decide whether this perturbation leads to a significant alteration in TAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor TAP1 expression. Decide whether this perturbation leads to a significant alteration in TAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and AC005540.3 expression is quantified. Does this perturbation result in a significant change in AC005540.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and AC005540.3 expression is quantified. Does this perturbation result in a significant change in AC005540.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of QSER1. Does perturbing P4HB lead to a significant change in QSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of QSER1. Does perturbing P4HB lead to a significant change in QSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
523,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and DDX6 expression is observed. Does this perturbation lead to a significant difference in DDX6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and DDX6 expression is observed. Does this perturbation lead to a significant difference in DDX6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of SERPINF2. Does perturbing SLC35B1 lead to a significant change in SERPINF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of SERPINF2. Does perturbing SLC35B1 lead to a significant change in SERPINF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of RP11-24F11.2. Does this perturbation cause a significant change in RP11-24F11.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of RP11-24F11.2. Does this perturbation cause a significant change in RP11-24F11.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in P4HB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in P4HB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3728,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor ARHGAP11A expression. Decide whether this perturbation leads to a significant alteration in ARHGAP11A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor ARHGAP11A expression. Decide whether this perturbation leads to a significant alteration in ARHGAP11A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in RP11-789C1.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in RP11-789C1.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of CDT1. Does perturbing SPCS2 lead to a significant change in CDT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of CDT1. Does perturbing SPCS2 lead to a significant change in CDT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of PDE9A is measured. Determine whether PDE9A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of PDE9A is measured. Determine whether PDE9A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and PIK3R1 expression is measured. Determine whether PIK3R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and PIK3R1 expression is measured. Determine whether PIK3R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of DUSP21. Does perturbing MARS lead to a significant change in DUSP21 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of DUSP21. Does perturbing MARS lead to a significant change in DUSP21 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of ROCK1. Does perturbing SPCS2 lead to a significant change in ROCK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of ROCK1. Does perturbing SPCS2 lead to a significant change in ROCK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of RASGRP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of RASGRP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1343,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and NSD1 expression is observed. Does this perturbation lead to a significant difference in NSD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and NSD1 expression is observed. Does this perturbation lead to a significant difference in NSD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of LTN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of LTN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4008,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor IL2RB expression. Decide whether this perturbation leads to a significant alteration in IL2RB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor IL2RB expression. Decide whether this perturbation leads to a significant alteration in IL2RB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of KCNH7. Does perturbing MTHFD1 lead to a significant change in KCNH7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of KCNH7. Does perturbing MTHFD1 lead to a significant change in KCNH7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of ZNF280B. Does this perturbation cause a significant change in ZNF280B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of ZNF280B. Does this perturbation cause a significant change in ZNF280B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of IL13RA1 is measured. Determine whether IL13RA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of IL13RA1 is measured. Determine whether IL13RA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of HIST1H3D is measured. Determine whether HIST1H3D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of HIST1H3D is measured. Determine whether HIST1H3D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
233,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and PTPRC expression is observed. Does this perturbation lead to a significant difference in PTPRC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and PTPRC expression is observed. Does this perturbation lead to a significant difference in PTPRC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of EP300 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of EP300 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of SPEN is measured. Determine whether SPEN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of SPEN is measured. Determine whether SPEN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2708,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RAI14 expression. Decide whether this perturbation leads to a significant alteration in RAI14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RAI14 expression. Decide whether this perturbation leads to a significant alteration in RAI14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and TLK2 expression is measured. Determine whether TLK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and TLK2 expression is measured. Determine whether TLK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of UBE2V1. Does this perturbation cause a significant change in UBE2V1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of UBE2V1. Does this perturbation cause a significant change in UBE2V1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and ZNF341 expression is quantified. Does this perturbation result in a significant change in ZNF341 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and ZNF341 expression is quantified. Does this perturbation result in a significant change in ZNF341 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of RP11-381O7.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of RP11-381O7.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of CASP8. Does perturbing DDIT3 lead to a significant change in CASP8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of CASP8. Does perturbing DDIT3 lead to a significant change in CASP8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3848,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor TRPM4 expression. Decide whether this perturbation leads to a significant alteration in TRPM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor TRPM4 expression. Decide whether this perturbation leads to a significant alteration in TRPM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of SNHG10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of SNHG10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in CD46 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in CD46 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in STARD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in STARD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of TSC22D4. Does this perturbation cause a significant change in TSC22D4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of TSC22D4. Does this perturbation cause a significant change in TSC22D4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3208,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor GSN expression. Decide whether this perturbation leads to a significant alteration in GSN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor GSN expression. Decide whether this perturbation leads to a significant alteration in GSN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of SLBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of SLBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
770,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of JUND is measured. Does this perturbation cause a significant change in JUND expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of JUND is measured. Does this perturbation cause a significant change in JUND expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of RSAD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of RSAD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of TOPBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of TOPBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and RBM12B-AS1 expression is quantified. Does this perturbation result in a significant change in RBM12B-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and RBM12B-AS1 expression is quantified. Does this perturbation result in a significant change in RBM12B-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of NFE2L3. Does this perturbation cause a significant change in NFE2L3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of NFE2L3. Does this perturbation cause a significant change in NFE2L3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of CDT1 is measured. Determine whether CDT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of CDT1 is measured. Determine whether CDT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of CELF6 is measured. Determine whether CELF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of CELF6 is measured. Determine whether CELF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4618,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor P4HB expression. Decide whether this perturbation leads to a significant alteration in P4HB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor P4HB expression. Decide whether this perturbation leads to a significant alteration in P4HB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
230,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of PTPRC is measured. Does this perturbation cause a significant change in PTPRC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of PTPRC is measured. Does this perturbation cause a significant change in PTPRC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and DNTTIP2 expression is quantified. Does this perturbation result in a significant change in DNTTIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and DNTTIP2 expression is quantified. Does this perturbation result in a significant change in DNTTIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and UBE3A expression is quantified. Does this perturbation result in a significant change in UBE3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and UBE3A expression is quantified. Does this perturbation result in a significant change in UBE3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in USP37 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in USP37 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3328,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor NPAT expression. Decide whether this perturbation leads to a significant alteration in NPAT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor NPAT expression. Decide whether this perturbation leads to a significant alteration in NPAT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of ESCO1. Does this perturbation cause a significant change in ESCO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of ESCO1. Does this perturbation cause a significant change in ESCO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4080,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of SPEN is measured. Does this perturbation cause a significant change in SPEN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of SPEN is measured. Does this perturbation cause a significant change in SPEN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of ANKRD33 is measured. Determine whether ANKRD33 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of ANKRD33 is measured. Determine whether ANKRD33 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of CTNNB1. Does this perturbation cause a significant change in CTNNB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of CTNNB1. Does this perturbation cause a significant change in CTNNB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of ANKRD33 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of ANKRD33 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and RP11-573D15.2 expression is measured. Determine whether RP11-573D15.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and RP11-573D15.2 expression is measured. Determine whether RP11-573D15.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
380,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of HIST1H2AM is measured. Does this perturbation cause a significant change in HIST1H2AM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of HIST1H2AM is measured. Does this perturbation cause a significant change in HIST1H2AM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and IL18R1 expression is measured. Determine whether IL18R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and IL18R1 expression is measured. Determine whether IL18R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of KDM1B. Does this perturbation cause a significant change in KDM1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of KDM1B. Does this perturbation cause a significant change in KDM1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in RP11-435O5.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in RP11-435O5.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of TACC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of TACC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in EIF4B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in EIF4B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and KCTD19 expression is quantified. Does this perturbation result in a significant change in KCTD19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and KCTD19 expression is quantified. Does this perturbation result in a significant change in KCTD19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of ZNF341 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of ZNF341 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of HPCAL1. Does this perturbation cause a significant change in HPCAL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of HPCAL1. Does this perturbation cause a significant change in HPCAL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4480,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of PPP1R16B is measured. Does this perturbation cause a significant change in PPP1R16B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of PPP1R16B is measured. Does this perturbation cause a significant change in PPP1R16B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of S100A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of S100A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and PIK3IP1 expression is quantified. Does this perturbation result in a significant change in PIK3IP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and PIK3IP1 expression is quantified. Does this perturbation result in a significant change in PIK3IP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2970,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of HPCAL1 is measured. Does this perturbation cause a significant change in HPCAL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of HPCAL1 is measured. Does this perturbation cause a significant change in HPCAL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of WHAMM is measured. Determine whether WHAMM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of WHAMM is measured. Determine whether WHAMM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in CLINT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in CLINT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of PRSS57. Does perturbing TMEM167A lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of PRSS57. Does perturbing TMEM167A lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of LTBP1 is measured. Determine whether LTBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of LTBP1 is measured. Determine whether LTBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PIF1. Does perturbing SARS lead to a significant change in PIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PIF1. Does perturbing SARS lead to a significant change in PIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4903,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and CHD3 expression is observed. Does this perturbation lead to a significant difference in CHD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and CHD3 expression is observed. Does this perturbation lead to a significant difference in CHD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2090,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of LTN1 is measured. Determine whether LTN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of LTN1 is measured. Determine whether LTN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2750,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RP11-685N10.1 is measured. Does this perturbation cause a significant change in RP11-685N10.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RP11-685N10.1 is measured. Does this perturbation cause a significant change in RP11-685N10.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
763,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and HLA-AS1 expression is observed. Does this perturbation lead to a significant difference in HLA-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and HLA-AS1 expression is observed. Does this perturbation lead to a significant difference in HLA-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of SP100 is measured. Determine whether SP100 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of SP100 is measured. Determine whether SP100 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1170,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of BAMBI is measured. Does this perturbation cause a significant change in BAMBI expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of BAMBI is measured. Does this perturbation cause a significant change in BAMBI expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1958,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of SLC25A35 is measured. Determine whether SLC25A35 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of SLC25A35 is measured. Determine whether SLC25A35 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and C12orf23 expression is measured. Determine whether C12orf23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and C12orf23 expression is measured. Determine whether C12orf23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
63,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RIOK3 expression is observed. Does this perturbation lead to a significant difference in RIOK3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RIOK3 expression is observed. Does this perturbation lead to a significant difference in RIOK3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and HAGH expression is quantified. Does this perturbation result in a significant change in HAGH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and HAGH expression is quantified. Does this perturbation result in a significant change in HAGH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of RP11-573D15.9 is measured. Determine whether RP11-573D15.9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of RP11-573D15.9 is measured. Determine whether RP11-573D15.9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4368,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor USP34 expression. Decide whether this perturbation leads to a significant alteration in USP34 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor USP34 expression. Decide whether this perturbation leads to a significant alteration in USP34 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PSMD14 is measured. Determine whether PSMD14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PSMD14 is measured. Determine whether PSMD14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and CD58 expression is quantified. Does this perturbation result in a significant change in CD58 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and CD58 expression is quantified. Does this perturbation result in a significant change in CD58 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of LTN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of LTN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3628,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor NRIP1 expression. Decide whether this perturbation leads to a significant alteration in NRIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor NRIP1 expression. Decide whether this perturbation leads to a significant alteration in NRIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of GUSB. Does this perturbation cause a significant change in GUSB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of GUSB. Does this perturbation cause a significant change in GUSB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of OXLD1 is measured. Determine whether OXLD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of OXLD1 is measured. Determine whether OXLD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and RP11-157D23.2 expression is quantified. Does this perturbation result in a significant change in RP11-157D23.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and RP11-157D23.2 expression is quantified. Does this perturbation result in a significant change in RP11-157D23.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of PELO. Does perturbing TMED10 lead to a significant change in PELO expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of PELO. Does perturbing TMED10 lead to a significant change in PELO expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in DDX3X expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in DDX3X expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3700,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of PARP11 is measured. Does this perturbation cause a significant change in PARP11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of PARP11 is measured. Does this perturbation cause a significant change in PARP11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
468,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor ERV3-1 expression. Decide whether this perturbation leads to a significant alteration in ERV3-1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor ERV3-1 expression. Decide whether this perturbation leads to a significant alteration in ERV3-1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of KIAA1586 is measured. Determine whether KIAA1586 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of KIAA1586 is measured. Determine whether KIAA1586 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of EP300 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of EP300 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1090,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of RP11-328J2.1 is measured. Does this perturbation cause a significant change in RP11-328J2.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of RP11-328J2.1 is measured. Does this perturbation cause a significant change in RP11-328J2.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in RP11-434H6.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in RP11-434H6.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1200,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of GMEB1 is measured. Does this perturbation cause a significant change in GMEB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of GMEB1 is measured. Does this perturbation cause a significant change in GMEB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of HERPUD1. Does perturbing FECH lead to a significant change in HERPUD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of HERPUD1. Does perturbing FECH lead to a significant change in HERPUD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of HIST1H3D. Does this perturbation cause a significant change in HIST1H3D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of HIST1H3D. Does this perturbation cause a significant change in HIST1H3D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of SIGLEC6 is measured. Determine whether SIGLEC6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of SIGLEC6 is measured. Determine whether SIGLEC6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of RP11-390B4.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of RP11-390B4.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in KCTD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in KCTD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in ZNF429 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in ZNF429 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of SIGLEC6. Does this perturbation cause a significant change in SIGLEC6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of SIGLEC6. Does this perturbation cause a significant change in SIGLEC6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of RP11-212I21.4 is measured. Determine whether RP11-212I21.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of RP11-212I21.4 is measured. Determine whether RP11-212I21.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of RILPL2 is measured. Determine whether RILPL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of RILPL2 is measured. Determine whether RILPL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in RP11-242O24.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in RP11-242O24.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1810,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of NFAT5 is measured. Does this perturbation cause a significant change in NFAT5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of NFAT5 is measured. Does this perturbation cause a significant change in NFAT5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and MTPN expression is quantified. Does this perturbation result in a significant change in MTPN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and MTPN expression is quantified. Does this perturbation result in a significant change in MTPN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of SMIM14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of SMIM14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and GUSB expression is measured. Determine whether GUSB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and GUSB expression is measured. Determine whether GUSB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and ARHGAP11A expression is quantified. Does this perturbation result in a significant change in ARHGAP11A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and ARHGAP11A expression is quantified. Does this perturbation result in a significant change in ARHGAP11A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and NFE2L3 expression is quantified. Does this perturbation result in a significant change in NFE2L3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and NFE2L3 expression is quantified. Does this perturbation result in a significant change in NFE2L3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and NOSTRIN expression is quantified. Does this perturbation result in a significant change in NOSTRIN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and NOSTRIN expression is quantified. Does this perturbation result in a significant change in NOSTRIN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4340,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of HIST1H1D is measured. Does this perturbation cause a significant change in HIST1H1D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of HIST1H1D is measured. Does this perturbation cause a significant change in HIST1H1D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of PIK3R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of PIK3R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of OBSCN. Does perturbing HYOU1 lead to a significant change in OBSCN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of OBSCN. Does perturbing HYOU1 lead to a significant change in OBSCN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
588,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor MYH7B expression. Decide whether this perturbation leads to a significant alteration in MYH7B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor MYH7B expression. Decide whether this perturbation leads to a significant alteration in MYH7B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of SNHG10 is measured. Determine whether SNHG10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of SNHG10 is measured. Determine whether SNHG10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and RP11-95O2.5 expression is quantified. Does this perturbation result in a significant change in RP11-95O2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and RP11-95O2.5 expression is quantified. Does this perturbation result in a significant change in RP11-95O2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of HAGH is measured. Determine whether HAGH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of HAGH is measured. Determine whether HAGH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in IRF7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in IRF7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
273,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and DUT expression is observed. Does this perturbation lead to a significant difference in DUT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and DUT expression is observed. Does this perturbation lead to a significant difference in DUT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
813,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and DNTTIP2 expression is observed. Does this perturbation lead to a significant difference in DNTTIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and DNTTIP2 expression is observed. Does this perturbation lead to a significant difference in DNTTIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of SKIL. Does this perturbation cause a significant change in SKIL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of SKIL. Does this perturbation cause a significant change in SKIL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and CFH expression is quantified. Does this perturbation result in a significant change in CFH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and CFH expression is quantified. Does this perturbation result in a significant change in CFH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and CENPC expression is measured. Determine whether CENPC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and CENPC expression is measured. Determine whether CENPC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3763,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and RNF19A expression is observed. Does this perturbation lead to a significant difference in RNF19A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and RNF19A expression is observed. Does this perturbation lead to a significant difference in RNF19A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and IRF7 expression is measured. Determine whether IRF7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and IRF7 expression is measured. Determine whether IRF7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2063,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and RTN2 expression is observed. Does this perturbation lead to a significant difference in RTN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and RTN2 expression is observed. Does this perturbation lead to a significant difference in RTN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of PAK1IP1 is measured. Determine whether PAK1IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of PAK1IP1 is measured. Determine whether PAK1IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and TFPI expression is measured. Determine whether TFPI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and TFPI expression is measured. Determine whether TFPI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2073,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and MANF expression is observed. Does this perturbation lead to a significant difference in MANF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and MANF expression is observed. Does this perturbation lead to a significant difference in MANF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and ANKRD11 expression is quantified. Does this perturbation result in a significant change in ANKRD11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and ANKRD11 expression is quantified. Does this perturbation result in a significant change in ANKRD11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and ROCK1 expression is quantified. Does this perturbation result in a significant change in ROCK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and ROCK1 expression is quantified. Does this perturbation result in a significant change in ROCK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1963,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and ARHGDIB expression is observed. Does this perturbation lead to a significant difference in ARHGDIB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and ARHGDIB expression is observed. Does this perturbation lead to a significant difference in ARHGDIB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in RSL24D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in RSL24D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and DOK3 expression is quantified. Does this perturbation result in a significant change in DOK3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and DOK3 expression is quantified. Does this perturbation result in a significant change in DOK3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and DDX6 expression is measured. Determine whether DDX6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and DDX6 expression is measured. Determine whether DDX6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of SPINK5 is measured. Determine whether SPINK5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of SPINK5 is measured. Determine whether SPINK5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2193,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and SLC26A1 expression is observed. Does this perturbation lead to a significant difference in SLC26A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and SLC26A1 expression is observed. Does this perturbation lead to a significant difference in SLC26A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of CASP8 is measured. Determine whether CASP8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of CASP8 is measured. Determine whether CASP8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and BAMBI expression is quantified. Does this perturbation result in a significant change in BAMBI expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and BAMBI expression is quantified. Does this perturbation result in a significant change in BAMBI expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and TACC3 expression is measured. Determine whether TACC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and TACC3 expression is measured. Determine whether TACC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of CDK13 is measured. Determine whether CDK13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of CDK13 is measured. Determine whether CDK13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
940,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of RP11-789C1.1 is measured. Does this perturbation cause a significant change in RP11-789C1.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of RP11-789C1.1 is measured. Does this perturbation cause a significant change in RP11-789C1.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and VIM-AS1 expression is measured. Determine whether VIM-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and VIM-AS1 expression is measured. Determine whether VIM-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
730,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of BRWD3 is measured. Does this perturbation cause a significant change in BRWD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of BRWD3 is measured. Does this perturbation cause a significant change in BRWD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and MS4A6E expression is measured. Determine whether MS4A6E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and MS4A6E expression is measured. Determine whether MS4A6E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3963,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2810,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of CDKN2C is measured. Does this perturbation cause a significant change in CDKN2C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of CDKN2C is measured. Does this perturbation cause a significant change in CDKN2C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5113,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and GATA2 expression is observed. Does this perturbation lead to a significant difference in GATA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and GATA2 expression is observed. Does this perturbation lead to a significant difference in GATA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and GSN expression is quantified. Does this perturbation result in a significant change in GSN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and GSN expression is quantified. Does this perturbation result in a significant change in GSN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of GUSB. Does perturbing TMEM167A lead to a significant change in GUSB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of GUSB. Does perturbing TMEM167A lead to a significant change in GUSB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of GNPTG is measured. Determine whether GNPTG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of GNPTG is measured. Determine whether GNPTG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and PSORS1C1 expression is quantified. Does this perturbation result in a significant change in PSORS1C1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and PSORS1C1 expression is quantified. Does this perturbation result in a significant change in PSORS1C1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and MANF expression is quantified. Does this perturbation result in a significant change in MANF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and MANF expression is quantified. Does this perturbation result in a significant change in MANF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
62,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RIOK3 expression is quantified. Does this perturbation result in a significant change in RIOK3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RIOK3 expression is quantified. Does this perturbation result in a significant change in RIOK3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and CD58 expression is measured. Determine whether CD58 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and CD58 expression is measured. Determine whether CD58 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of IL13RA1. Does this perturbation cause a significant change in IL13RA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of IL13RA1. Does this perturbation cause a significant change in IL13RA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of RP11-138C9.1. Does perturbing TIMM23 lead to a significant change in RP11-138C9.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of RP11-138C9.1. Does perturbing TIMM23 lead to a significant change in RP11-138C9.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2940,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of SKIL is measured. Does this perturbation cause a significant change in SKIL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of SKIL is measured. Does this perturbation cause a significant change in SKIL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of AKAP11. Does this perturbation cause a significant change in AKAP11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of AKAP11. Does this perturbation cause a significant change in AKAP11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
40,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of LPAR5 is measured. Does this perturbation cause a significant change in LPAR5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of LPAR5 is measured. Does this perturbation cause a significant change in LPAR5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of HM13. Does perturbing DHDDS lead to a significant change in HM13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of HM13. Does perturbing DHDDS lead to a significant change in HM13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and HIST1H2BC expression is quantified. Does this perturbation result in a significant change in HIST1H2BC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and HIST1H2BC expression is quantified. Does this perturbation result in a significant change in HIST1H2BC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of CTSV is measured. Determine whether CTSV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of CTSV is measured. Determine whether CTSV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in KIAA1731 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in KIAA1731 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and SLFNL1 expression is measured. Determine whether SLFNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and SLFNL1 expression is measured. Determine whether SLFNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of REST. Does this perturbation cause a significant change in REST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of REST. Does this perturbation cause a significant change in REST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3850,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of PHF21A is measured. Does this perturbation cause a significant change in PHF21A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of PHF21A is measured. Does this perturbation cause a significant change in PHF21A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of HIST1H2AM. Does this perturbation cause a significant change in HIST1H2AM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of HIST1H2AM. Does this perturbation cause a significant change in HIST1H2AM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of EXO1. Does perturbing SEC61B lead to a significant change in EXO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of EXO1. Does perturbing SEC61B lead to a significant change in EXO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and SLC26A1 expression is quantified. Does this perturbation result in a significant change in SLC26A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and SLC26A1 expression is quantified. Does this perturbation result in a significant change in SLC26A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of GS1-166A23.1. Does perturbing HSPA5 lead to a significant change in GS1-166A23.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of GS1-166A23.1. Does perturbing HSPA5 lead to a significant change in GS1-166A23.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in IL32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in IL32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in KIF4A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in KIF4A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of KLF3. Does perturbing GNPNAT1 lead to a significant change in KLF3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of KLF3. Does perturbing GNPNAT1 lead to a significant change in KLF3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
980,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of TOB2 is measured. Does this perturbation cause a significant change in TOB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of TOB2 is measured. Does this perturbation cause a significant change in TOB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and ANKLE2 expression is measured. Determine whether ANKLE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and ANKLE2 expression is measured. Determine whether ANKLE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2308,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and PLA2G15 expression is measured. Determine whether PLA2G15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and PLA2G15 expression is measured. Determine whether PLA2G15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2740,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of DUSP21 is measured. Does this perturbation cause a significant change in DUSP21 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of DUSP21 is measured. Does this perturbation cause a significant change in DUSP21 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of FYTTD1 is measured. Determine whether FYTTD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of FYTTD1 is measured. Determine whether FYTTD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of APOL4. Does perturbing AMIGO3 lead to a significant change in APOL4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of APOL4. Does perturbing AMIGO3 lead to a significant change in APOL4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of RP11-304M2.5. Does this perturbation cause a significant change in RP11-304M2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of RP11-304M2.5. Does this perturbation cause a significant change in RP11-304M2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4643,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and S100A11 expression is observed. Does this perturbation lead to a significant difference in S100A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and S100A11 expression is observed. Does this perturbation lead to a significant difference in S100A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in RP11-838N2.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in RP11-838N2.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of ZEB2. Does this perturbation cause a significant change in ZEB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of ZEB2. Does this perturbation cause a significant change in ZEB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and ATP11B expression is measured. Determine whether ATP11B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and ATP11B expression is measured. Determine whether ATP11B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and NUF2 expression is quantified. Does this perturbation result in a significant change in NUF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and NUF2 expression is quantified. Does this perturbation result in a significant change in NUF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and TSNAXIP1 expression is measured. Determine whether TSNAXIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and TSNAXIP1 expression is measured. Determine whether TSNAXIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of RP11-3D4.3 is measured. Determine whether RP11-3D4.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of RP11-3D4.3 is measured. Determine whether RP11-3D4.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of GPRC5C is measured. Determine whether GPRC5C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of GPRC5C is measured. Determine whether GPRC5C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and SLBP expression is measured. Determine whether SLBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and SLBP expression is measured. Determine whether SLBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of RP11-24F11.2 is measured. Determine whether RP11-24F11.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of RP11-24F11.2 is measured. Determine whether RP11-24F11.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1568,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor DOCK8 expression. Decide whether this perturbation leads to a significant alteration in DOCK8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor DOCK8 expression. Decide whether this perturbation leads to a significant alteration in DOCK8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3890,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of ACRV1 is measured. Does this perturbation cause a significant change in ACRV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of ACRV1 is measured. Does this perturbation cause a significant change in ACRV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of BACH2 is measured. Determine whether BACH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of BACH2 is measured. Determine whether BACH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of SPAST. Does this perturbation cause a significant change in SPAST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of SPAST. Does this perturbation cause a significant change in SPAST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3948,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ROBO1 expression. Decide whether this perturbation leads to a significant alteration in ROBO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ROBO1 expression. Decide whether this perturbation leads to a significant alteration in ROBO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of GDF11. Does this perturbation cause a significant change in GDF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of GDF11. Does this perturbation cause a significant change in GDF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of ASPM. Does this perturbation cause a significant change in ASPM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of ASPM. Does this perturbation cause a significant change in ASPM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and SNHG10 expression is quantified. Does this perturbation result in a significant change in SNHG10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and SNHG10 expression is quantified. Does this perturbation result in a significant change in SNHG10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of RP11-90P5.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of RP11-90P5.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in PPP1R16B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in PPP1R16B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in CELF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in CELF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
490,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of LDLR is measured. Does this perturbation cause a significant change in LDLR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of LDLR is measured. Does this perturbation cause a significant change in LDLR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of RP11-328J2.1 is measured. Determine whether RP11-328J2.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of RP11-328J2.1 is measured. Determine whether RP11-328J2.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3288,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor AC018878.3 expression. Decide whether this perturbation leads to a significant alteration in AC018878.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor AC018878.3 expression. Decide whether this perturbation leads to a significant alteration in AC018878.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and CTCFL expression is measured. Determine whether CTCFL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and CTCFL expression is measured. Determine whether CTCFL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of KLK1. Does this perturbation cause a significant change in KLK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of KLK1. Does this perturbation cause a significant change in KLK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of NCKAP1L. Does perturbing SRPR lead to a significant change in NCKAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of NCKAP1L. Does perturbing SRPR lead to a significant change in NCKAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
873,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and RSL24D1 expression is observed. Does this perturbation lead to a significant difference in RSL24D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and RSL24D1 expression is observed. Does this perturbation lead to a significant difference in RSL24D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in KLF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in KLF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4398,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor ATAD2B expression. Decide whether this perturbation leads to a significant alteration in ATAD2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor ATAD2B expression. Decide whether this perturbation leads to a significant alteration in ATAD2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
0,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of ZNF429 is measured. Does this perturbation cause a significant change in ZNF429 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of ZNF429 is measured. Does this perturbation cause a significant change in ZNF429 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
658,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor POU2F2 expression. Decide whether this perturbation leads to a significant alteration in POU2F2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor POU2F2 expression. Decide whether this perturbation leads to a significant alteration in POU2F2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and AC015987.2 expression is quantified. Does this perturbation result in a significant change in AC015987.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and AC015987.2 expression is quantified. Does this perturbation result in a significant change in AC015987.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of HIST1H2BC. Does this perturbation cause a significant change in HIST1H2BC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of HIST1H2BC. Does this perturbation cause a significant change in HIST1H2BC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of IL2RB. Does perturbing EIF2S1 lead to a significant change in IL2RB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of IL2RB. Does perturbing EIF2S1 lead to a significant change in IL2RB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
368,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor DOCK11 expression. Decide whether this perturbation leads to a significant alteration in DOCK11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor DOCK11 expression. Decide whether this perturbation leads to a significant alteration in DOCK11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and PHF21A expression is measured. Determine whether PHF21A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and PHF21A expression is measured. Determine whether PHF21A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3563,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and ZNF292 expression is observed. Does this perturbation lead to a significant difference in ZNF292 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and ZNF292 expression is observed. Does this perturbation lead to a significant difference in ZNF292 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of VIM-AS1. Does this perturbation cause a significant change in VIM-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of VIM-AS1. Does this perturbation cause a significant change in VIM-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2500,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of UFD1L is measured. Does this perturbation cause a significant change in UFD1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of UFD1L is measured. Does this perturbation cause a significant change in UFD1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
370,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of HMGCS1 is measured. Does this perturbation cause a significant change in HMGCS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of HMGCS1 is measured. Does this perturbation cause a significant change in HMGCS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3990,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of RP11-242O24.5 is measured. Does this perturbation cause a significant change in RP11-242O24.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of RP11-242O24.5 is measured. Does this perturbation cause a significant change in RP11-242O24.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in QSER1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in QSER1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4773,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and HIST1H2BC expression is observed. Does this perturbation lead to a significant difference in HIST1H2BC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and HIST1H2BC expression is observed. Does this perturbation lead to a significant difference in HIST1H2BC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of MTPN. Does perturbing SEC61G lead to a significant change in MTPN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of MTPN. Does perturbing SEC61G lead to a significant change in MTPN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of TTC32. Does perturbing TTI1 lead to a significant change in TTC32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of TTC32. Does perturbing TTI1 lead to a significant change in TTC32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2553,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and MORC2-AS1 expression is observed. Does this perturbation lead to a significant difference in MORC2-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and MORC2-AS1 expression is observed. Does this perturbation lead to a significant difference in MORC2-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of TLN1 is measured. Determine whether TLN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of TLN1 is measured. Determine whether TLN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and LRRC4B expression is measured. Determine whether LRRC4B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and LRRC4B expression is measured. Determine whether LRRC4B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and NRIP1 expression is quantified. Does this perturbation result in a significant change in NRIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and NRIP1 expression is quantified. Does this perturbation result in a significant change in NRIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of PCF11. Does this perturbation cause a significant change in PCF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of PCF11. Does this perturbation cause a significant change in PCF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of JARID2. Does perturbing DDRGK1 lead to a significant change in JARID2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of JARID2. Does perturbing DDRGK1 lead to a significant change in JARID2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of DKFZP779L1853 is measured. Determine whether DKFZP779L1853 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of DKFZP779L1853 is measured. Determine whether DKFZP779L1853 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of IRF7 is measured. Determine whether IRF7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of IRF7 is measured. Determine whether IRF7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2578,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor ACE expression. Decide whether this perturbation leads to a significant alteration in ACE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor ACE expression. Decide whether this perturbation leads to a significant alteration in ACE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and CDCA3 expression is measured. Determine whether CDCA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and CDCA3 expression is measured. Determine whether CDCA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in NXF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in NXF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and TSPAN33 expression is measured. Determine whether TSPAN33 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and TSPAN33 expression is measured. Determine whether TSPAN33 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of DNMBP. Does perturbing TMED10 lead to a significant change in DNMBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of DNMBP. Does perturbing TMED10 lead to a significant change in DNMBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of VPS41. Does perturbing HARS lead to a significant change in VPS41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of VPS41. Does perturbing HARS lead to a significant change in VPS41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in CTD-2267D19.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in CTD-2267D19.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of GALNT7 is measured. Determine whether GALNT7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of GALNT7 is measured. Determine whether GALNT7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of FAM212A. Does perturbing NEDD8 lead to a significant change in FAM212A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of FAM212A. Does perturbing NEDD8 lead to a significant change in FAM212A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of SLC25A35 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of SLC25A35 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of RSAD2 is measured. Determine whether RSAD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of RSAD2 is measured. Determine whether RSAD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and RP11-138C9.1 expression is measured. Determine whether RP11-138C9.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and RP11-138C9.1 expression is measured. Determine whether RP11-138C9.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."