[
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RP11-141B14.1 expression is measured. Determine whether RP11-141B14.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RP11-141B14.1 expression is measured. Determine whether RP11-141B14.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of GUSB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of GUSB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1937
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and CD46 expression is quantified. Does this perturbation result in a significant change in CD46 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and CD46 expression is quantified. Does this perturbation result in a significant change in CD46 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4212
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in PCF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in PCF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5065
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and OR2T6 expression is observed. Does this perturbation lead to a significant difference in OR2T6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and OR2T6 expression is observed. Does this perturbation lead to a significant difference in OR2T6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1843
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of ZCCHC11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of ZCCHC11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4997
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in PGM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in PGM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2085
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of RP11-157D23.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of RP11-157D23.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4427
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of GALNT7. Does perturbing FECH lead to a significant change in GALNT7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of GALNT7. Does perturbing FECH lead to a significant change in GALNT7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4381
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of CD9. Does perturbing SRPR lead to a significant change in CD9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of CD9. Does perturbing SRPR lead to a significant change in CD9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":421
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of MT2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of MT2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3167
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and RNF139-AS1 expression is measured. Determine whether RNF139-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and RNF139-AS1 expression is measured. Determine whether RNF139-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2529
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2789
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of FCGRT. Does this perturbation cause a significant change in FCGRT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of FCGRT. Does this perturbation cause a significant change in FCGRT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3534
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of QSER1. Does this perturbation cause a significant change in QSER1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of QSER1. Does this perturbation cause a significant change in QSER1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5004
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and GMEB1 expression is quantified. Does this perturbation result in a significant change in GMEB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and GMEB1 expression is quantified. Does this perturbation result in a significant change in GMEB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1202
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of ACE. Does perturbing FARSB lead to a significant change in ACE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of ACE. Does perturbing FARSB lead to a significant change in ACE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2571
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and DOCK11 expression is quantified. Does this perturbation result in a significant change in DOCK11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and DOCK11 expression is quantified. Does this perturbation result in a significant change in DOCK11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":362
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor RIMS3 expression. Decide whether this perturbation leads to a significant alteration in RIMS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor RIMS3 expression. Decide whether this perturbation leads to a significant alteration in RIMS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":168
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of KIAA1432 is measured. Does this perturbation cause a significant change in KIAA1432 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of KIAA1432 is measured. Does this perturbation cause a significant change in KIAA1432 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3750
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of PLA2G15. Does perturbing HYOU1 lead to a significant change in PLA2G15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of PLA2G15. Does perturbing HYOU1 lead to a significant change in PLA2G15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3831
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of TKTL1 is measured. Determine whether TKTL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of TKTL1 is measured. Determine whether TKTL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":176
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of RP11-430H10.1. Does perturbing P4HB lead to a significant change in RP11-430H10.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of RP11-430H10.1. Does perturbing P4HB lead to a significant change in RP11-430H10.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5021
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and ANKLE2 expression is observed. Does this perturbation lead to a significant difference in ANKLE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and ANKLE2 expression is observed. Does this perturbation lead to a significant difference in ANKLE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2313
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and LAMP2 expression is measured. Determine whether LAMP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and LAMP2 expression is measured. Determine whether LAMP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5049
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and MARCH8 expression is quantified. Does this perturbation result in a significant change in MARCH8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and MARCH8 expression is quantified. Does this perturbation result in a significant change in MARCH8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1432
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of GATA3 is measured. Determine whether GATA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of GATA3 is measured. Determine whether GATA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":886
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and CD46 expression is observed. Does this perturbation lead to a significant difference in CD46 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and CD46 expression is observed. Does this perturbation lead to a significant difference in CD46 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4213
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in RP11-90P5.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in RP11-90P5.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":405
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of NINJ2. Does perturbing SLC39A7 lead to a significant change in NINJ2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of NINJ2. Does perturbing SLC39A7 lead to a significant change in NINJ2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2141
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of KIAA1432 is measured. Determine whether KIAA1432 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of KIAA1432 is measured. Determine whether KIAA1432 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3756
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and ATP6V1B2 expression is quantified. Does this perturbation result in a significant change in ATP6V1B2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and ATP6V1B2 expression is quantified. Does this perturbation result in a significant change in ATP6V1B2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1602
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of AC104532.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of AC104532.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2987
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of RP11-334C17.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of RP11-334C17.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1007
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of PCF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of PCF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5067
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor SLC27A2 expression. Decide whether this perturbation leads to a significant alteration in SLC27A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor SLC27A2 expression. Decide whether this perturbation leads to a significant alteration in SLC27A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3688
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and P4HA2 expression is quantified. Does this perturbation result in a significant change in P4HA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and P4HA2 expression is quantified. Does this perturbation result in a significant change in P4HA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of C1GALT1 is measured. Does this perturbation cause a significant change in C1GALT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of C1GALT1 is measured. Does this perturbation cause a significant change in C1GALT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2000
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of NINJ2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of NINJ2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2147
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and MARCH8 expression is measured. Determine whether MARCH8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and MARCH8 expression is measured. Determine whether MARCH8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1439
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4572
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and RP11-471M2.3 expression is measured. Determine whether RP11-471M2.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and RP11-471M2.3 expression is measured. Determine whether RP11-471M2.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2599
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of ATP6AP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of ATP6AP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1627
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of LINC00862. Does this perturbation cause a significant change in LINC00862 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of LINC00862. Does this perturbation cause a significant change in LINC00862 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4594
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of TAGLN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of TAGLN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1357
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of TTC18. Does perturbing TIMM44 lead to a significant change in TTC18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of TTC18. Does perturbing TIMM44 lead to a significant change in TTC18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3691
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor KIAA0922 expression. Decide whether this perturbation leads to a significant alteration in KIAA0922 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor KIAA0922 expression. Decide whether this perturbation leads to a significant alteration in KIAA0922 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3748
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and RP11-789C1.1 expression is measured. Determine whether RP11-789C1.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and RP11-789C1.1 expression is measured. Determine whether RP11-789C1.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":949
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and GCKR expression is observed. Does this perturbation lead to a significant difference in GCKR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and GCKR expression is observed. Does this perturbation lead to a significant difference in GCKR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4303
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and CTBS expression is measured. Determine whether CTBS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and CTBS expression is measured. Determine whether CTBS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4449
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and CEBPG expression is quantified. Does this perturbation result in a significant change in CEBPG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and CEBPG expression is quantified. Does this perturbation result in a significant change in CEBPG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and RP11-640M9.1 expression is observed. Does this perturbation lead to a significant difference in RP11-640M9.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and RP11-640M9.1 expression is observed. Does this perturbation lead to a significant difference in RP11-640M9.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1123
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and PCK2 expression is quantified. Does this perturbation result in a significant change in PCK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and PCK2 expression is quantified. Does this perturbation result in a significant change in PCK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":332
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of SERPING1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of SERPING1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3247
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and RP11-132A1.4 expression is measured. Determine whether RP11-132A1.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and RP11-132A1.4 expression is measured. Determine whether RP11-132A1.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":729
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in FYTTD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in FYTTD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2365
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of LINC00657 is measured. Does this perturbation cause a significant change in LINC00657 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of LINC00657 is measured. Does this perturbation cause a significant change in LINC00657 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":250
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4282
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor RP11-390B4.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-390B4.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor RP11-390B4.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-390B4.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4838
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of RP11-38P22.2 is measured. Determine whether RP11-38P22.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of RP11-38P22.2 is measured. Determine whether RP11-38P22.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1056
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of SETD5-AS1. Does perturbing UFL1 lead to a significant change in SETD5-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of SETD5-AS1. Does perturbing UFL1 lead to a significant change in SETD5-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1181
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and TTC32 expression is observed. Does this perturbation lead to a significant difference in TTC32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and TTC32 expression is observed. Does this perturbation lead to a significant difference in TTC32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3213
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ROBO1 is measured. Does this perturbation cause a significant change in ROBO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ROBO1 is measured. Does this perturbation cause a significant change in ROBO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3940
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and PLB1 expression is quantified. Does this perturbation result in a significant change in PLB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and PLB1 expression is quantified. Does this perturbation result in a significant change in PLB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4952
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of EP300 is measured. Does this perturbation cause a significant change in EP300 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of EP300 is measured. Does this perturbation cause a significant change in EP300 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1680
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and RP11-3D4.3 expression is quantified. Does this perturbation result in a significant change in RP11-3D4.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and RP11-3D4.3 expression is quantified. Does this perturbation result in a significant change in RP11-3D4.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3642
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor RP11-573D15.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-573D15.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor RP11-573D15.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-573D15.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3888
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and NOXA1 expression is measured. Determine whether NOXA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and NOXA1 expression is measured. Determine whether NOXA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1419
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of HIST1H2AM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of HIST1H2AM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":387
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and PTPN11 expression is measured. Determine whether PTPN11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and PTPN11 expression is measured. Determine whether PTPN11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":509
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of VPS41 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of VPS41 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":637
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and PRRC2B expression is measured. Determine whether PRRC2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and PRRC2B expression is measured. Determine whether PRRC2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":909
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in LTB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in LTB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":325
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of GMEB1 is measured. Determine whether GMEB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of GMEB1 is measured. Determine whether GMEB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1206
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor RP11-666A20.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-666A20.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor RP11-666A20.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-666A20.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4238
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of EP300 is measured. Does this perturbation cause a significant change in EP300 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of EP300 is measured. Does this perturbation cause a significant change in EP300 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2050
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of RP11-430H10.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of RP11-430H10.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5027
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of NRIP1. Does perturbing EIF2S1 lead to a significant change in NRIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of NRIP1. Does perturbing EIF2S1 lead to a significant change in NRIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3621
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor ATF6 expression. Decide whether this perturbation leads to a significant alteration in ATF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor ATF6 expression. Decide whether this perturbation leads to a significant alteration in ATF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":858
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of CHD3 is measured. Does this perturbation cause a significant change in CHD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of CHD3 is measured. Does this perturbation cause a significant change in CHD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4900
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of TRPM4 is measured. Determine whether TRPM4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of TRPM4 is measured. Determine whether TRPM4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3846
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and RP11-212I21.4 expression is quantified. Does this perturbation result in a significant change in RP11-212I21.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and RP11-212I21.4 expression is quantified. Does this perturbation result in a significant change in RP11-212I21.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2032
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of SLC26A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of SLC26A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2197
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of DDX3X is measured. Determine whether DDX3X shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of DDX3X is measured. Determine whether DDX3X shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1086
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and C1GALT1 expression is quantified. Does this perturbation result in a significant change in C1GALT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and C1GALT1 expression is quantified. Does this perturbation result in a significant change in C1GALT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2002
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor LDLR expression. Decide whether this perturbation leads to a significant alteration in LDLR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor LDLR expression. Decide whether this perturbation leads to a significant alteration in LDLR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":498
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of SPEN. Does this perturbation cause a significant change in SPEN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of SPEN. Does this perturbation cause a significant change in SPEN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4084
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor LINC00938 expression. Decide whether this perturbation leads to a significant alteration in LINC00938 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor LINC00938 expression. Decide whether this perturbation leads to a significant alteration in LINC00938 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4108
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of NSD1. Does perturbing STT3A lead to a significant change in NSD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of NSD1. Does perturbing STT3A lead to a significant change in NSD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1341
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in TGOLN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in TGOLN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5095
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and AC012594.1 expression is observed. Does this perturbation lead to a significant difference in AC012594.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and AC012594.1 expression is observed. Does this perturbation lead to a significant difference in AC012594.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1673
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of CTNNB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of CTNNB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2457
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and RGS20 expression is quantified. Does this perturbation result in a significant change in RGS20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and RGS20 expression is quantified. Does this perturbation result in a significant change in RGS20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3122
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of SETX. Does perturbing GBF1 lead to a significant change in SETX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of SETX. Does perturbing GBF1 lead to a significant change in SETX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2471
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and DOK3 expression is measured. Determine whether DOK3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and DOK3 expression is measured. Determine whether DOK3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":269
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in SPEN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in SPEN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1575
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of CCDC69 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of CCDC69 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3447
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor SEC23IP expression. Decide whether this perturbation leads to a significant alteration in SEC23IP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor SEC23IP expression. Decide whether this perturbation leads to a significant alteration in SEC23IP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3978
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of HMGCS1. Does this perturbation cause a significant change in HMGCS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of HMGCS1. Does this perturbation cause a significant change in HMGCS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":374
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in SERPING1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in SERPING1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3245
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of ACRV1. Does this perturbation cause a significant change in ACRV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of ACRV1. Does this perturbation cause a significant change in ACRV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3894
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and SNRNP25 expression is observed. Does this perturbation lead to a significant difference in SNRNP25 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and SNRNP25 expression is observed. Does this perturbation lead to a significant difference in SNRNP25 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2153
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor H1FX expression. Decide whether this perturbation leads to a significant alteration in H1FX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor H1FX expression. Decide whether this perturbation leads to a significant alteration in H1FX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4678
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of VIM-AS1 is measured. Determine whether VIM-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of VIM-AS1 is measured. Determine whether VIM-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1726
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and CENPC expression is observed. Does this perturbation lead to a significant difference in CENPC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and CENPC expression is observed. Does this perturbation lead to a significant difference in CENPC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4453
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of AP000688.8. Does this perturbation cause a significant change in AP000688.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of AP000688.8. Does this perturbation cause a significant change in AP000688.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3334
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of IL32 is measured. Determine whether IL32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of IL32 is measured. Determine whether IL32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":566
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RAI14 expression is observed. Does this perturbation lead to a significant difference in RAI14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RAI14 expression is observed. Does this perturbation lead to a significant difference in RAI14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2703
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and CD9 expression is observed. Does this perturbation lead to a significant difference in CD9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and CD9 expression is observed. Does this perturbation lead to a significant difference in CD9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":423
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of S100A10. Does perturbing CARS lead to a significant change in S100A10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of S100A10. Does perturbing CARS lead to a significant change in S100A10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4871
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of WDR72. Does this perturbation cause a significant change in WDR72 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of WDR72. Does this perturbation cause a significant change in WDR72 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4134
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and ZC3H7A expression is quantified. Does this perturbation result in a significant change in ZC3H7A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and ZC3H7A expression is quantified. Does this perturbation result in a significant change in ZC3H7A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3672
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of USP37 is measured. Does this perturbation cause a significant change in USP37 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of USP37 is measured. Does this perturbation cause a significant change in USP37 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1730
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and IL18R1 expression is measured. Determine whether IL18R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and IL18R1 expression is measured. Determine whether IL18R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":359
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of PTPN11 is measured. Determine whether PTPN11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of PTPN11 is measured. Determine whether PTPN11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":506
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and SERPINH1 expression is quantified. Does this perturbation result in a significant change in SERPINH1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and SERPINH1 expression is quantified. Does this perturbation result in a significant change in SERPINH1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1642
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of ZFHX3. Does perturbing SEC61A1 lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of ZFHX3. Does perturbing SEC61A1 lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":311
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and TSPAN33 expression is quantified. Does this perturbation result in a significant change in TSPAN33 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and TSPAN33 expression is quantified. Does this perturbation result in a significant change in TSPAN33 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3522
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of EIF4B is measured. Does this perturbation cause a significant change in EIF4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of EIF4B is measured. Does this perturbation cause a significant change in EIF4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4960
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of HOTAIRM1 is measured. Determine whether HOTAIRM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of HOTAIRM1 is measured. Determine whether HOTAIRM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1266
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of HP1BP3. Does perturbing HARS lead to a significant change in HP1BP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of HP1BP3. Does perturbing HARS lead to a significant change in HP1BP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":611
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and YTHDF2 expression is observed. Does this perturbation lead to a significant difference in YTHDF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and YTHDF2 expression is observed. Does this perturbation lead to a significant difference in YTHDF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4923
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of ROCK1. Does this perturbation cause a significant change in ROCK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of ROCK1. Does this perturbation cause a significant change in ROCK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5154
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and NPDC1 expression is quantified. Does this perturbation result in a significant change in NPDC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and NPDC1 expression is quantified. Does this perturbation result in a significant change in NPDC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1322
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and RP11-435O5.4 expression is quantified. Does this perturbation result in a significant change in RP11-435O5.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and RP11-435O5.4 expression is quantified. Does this perturbation result in a significant change in RP11-435O5.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1192
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor KCNH7 expression. Decide whether this perturbation leads to a significant alteration in KCNH7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor KCNH7 expression. Decide whether this perturbation leads to a significant alteration in KCNH7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1788
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and ZNF292 expression is quantified. Does this perturbation result in a significant change in ZNF292 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and ZNF292 expression is quantified. Does this perturbation result in a significant change in ZNF292 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3562
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of HIST1H2BC is measured. Determine whether HIST1H2BC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of HIST1H2BC is measured. Determine whether HIST1H2BC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4776
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of SERPINH1. Does this perturbation cause a significant change in SERPINH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of SERPINH1. Does this perturbation cause a significant change in SERPINH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1644
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and POLR2J3 expression is observed. Does this perturbation lead to a significant difference in POLR2J3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and POLR2J3 expression is observed. Does this perturbation lead to a significant difference in POLR2J3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3793
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in RP11-2H8.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in RP11-2H8.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3595
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of LTB is measured. Determine whether LTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of LTB is measured. Determine whether LTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4706
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and DNASE2 expression is observed. Does this perturbation lead to a significant difference in DNASE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and DNASE2 expression is observed. Does this perturbation lead to a significant difference in DNASE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1633
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of GPRC5C. Does perturbing NEDD8 lead to a significant change in GPRC5C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of GPRC5C. Does perturbing NEDD8 lead to a significant change in GPRC5C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2221
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and AP000688.8 expression is quantified. Does this perturbation result in a significant change in AP000688.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and AP000688.8 expression is quantified. Does this perturbation result in a significant change in AP000688.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3332
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of SOBP. Does perturbing EIF2S1 lead to a significant change in SOBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of SOBP. Does perturbing EIF2S1 lead to a significant change in SOBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3631
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of SNHG10 is measured. Determine whether SNHG10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of SNHG10 is measured. Determine whether SNHG10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1316
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RP11-141B14.1 expression is quantified. Does this perturbation result in a significant change in RP11-141B14.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RP11-141B14.1 expression is quantified. Does this perturbation result in a significant change in RP11-141B14.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and AC096559.1 expression is observed. Does this perturbation lead to a significant difference in AC096559.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and AC096559.1 expression is observed. Does this perturbation lead to a significant difference in AC096559.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1873
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of HP1BP3 is measured. Determine whether HP1BP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of HP1BP3 is measured. Determine whether HP1BP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":616
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of WDR72 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of WDR72 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4137
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and TSC22D4 expression is observed. Does this perturbation lead to a significant difference in TSC22D4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and TSC22D4 expression is observed. Does this perturbation lead to a significant difference in TSC22D4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3273
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor KCTD19 expression. Decide whether this perturbation leads to a significant alteration in KCTD19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor KCTD19 expression. Decide whether this perturbation leads to a significant alteration in KCTD19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2688
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of RP11-640M9.1 is measured. Does this perturbation cause a significant change in RP11-640M9.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of RP11-640M9.1 is measured. Does this perturbation cause a significant change in RP11-640M9.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1120
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in RP11-16E12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in RP11-16E12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3235
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of ATP2A3. Does this perturbation cause a significant change in ATP2A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of ATP2A3. Does this perturbation cause a significant change in ATP2A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1834
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of CCRL2 is measured. Determine whether CCRL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of CCRL2 is measured. Determine whether CCRL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3556
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and ANKRD10 expression is measured. Determine whether ANKRD10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and ANKRD10 expression is measured. Determine whether ANKRD10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4359
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and RP11-363D14.1 expression is measured. Determine whether RP11-363D14.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and RP11-363D14.1 expression is measured. Determine whether RP11-363D14.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3059
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in LRIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in LRIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1455
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of VAMP2 is measured. Determine whether VAMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of VAMP2 is measured. Determine whether VAMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2906
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of RP11-471M2.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of RP11-471M2.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2597
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of PGM3. Does perturbing TTI2 lead to a significant change in PGM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of PGM3. Does perturbing TTI2 lead to a significant change in PGM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2081
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of GOT1 is measured. Determine whether GOT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of GOT1 is measured. Determine whether GOT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1116
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor CCDC69 expression. Decide whether this perturbation leads to a significant alteration in CCDC69 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor CCDC69 expression. Decide whether this perturbation leads to a significant alteration in CCDC69 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3448
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of ZNF280B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of ZNF280B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1287
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of PCF11 is measured. Does this perturbation cause a significant change in PCF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of PCF11 is measured. Does this perturbation cause a significant change in PCF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":540
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of LRIF1. Does this perturbation cause a significant change in LRIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of LRIF1. Does this perturbation cause a significant change in LRIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1454
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of FYTTD1 is measured. Does this perturbation cause a significant change in FYTTD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of FYTTD1 is measured. Does this perturbation cause a significant change in FYTTD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2360
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of CENPC is measured. Determine whether CENPC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of CENPC is measured. Determine whether CENPC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2186
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in RGS20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in RGS20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4945
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and TOB2 expression is observed. Does this perturbation lead to a significant difference in TOB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and TOB2 expression is observed. Does this perturbation lead to a significant difference in TOB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":983
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2123
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in KCNH7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in KCNH7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1785
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2092
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of TGOLN2 is measured. Determine whether TGOLN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of TGOLN2 is measured. Determine whether TGOLN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5096
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and ZNF292 expression is observed. Does this perturbation lead to a significant difference in ZNF292 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and ZNF292 expression is observed. Does this perturbation lead to a significant difference in ZNF292 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1503
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor ZCCHC11 expression. Decide whether this perturbation leads to a significant alteration in ZCCHC11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor ZCCHC11 expression. Decide whether this perturbation leads to a significant alteration in ZCCHC11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4998
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and KLK1 expression is observed. Does this perturbation lead to a significant difference in KLK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and KLK1 expression is observed. Does this perturbation lead to a significant difference in KLK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":203
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of CHST12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of CHST12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3467
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and SETX expression is quantified. Does this perturbation result in a significant change in SETX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and SETX expression is quantified. Does this perturbation result in a significant change in SETX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2472
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of SPCS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of SPCS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":697
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ZFP36L2 expression is quantified. Does this perturbation result in a significant change in ZFP36L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ZFP36L2 expression is quantified. Does this perturbation result in a significant change in ZFP36L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3452
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and POLR2J3 expression is measured. Determine whether POLR2J3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and POLR2J3 expression is measured. Determine whether POLR2J3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3799
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of MTPN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of MTPN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4737
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in RP11-138C9.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in RP11-138C9.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":835
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and RP11-247A12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-247A12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and RP11-247A12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-247A12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1663
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in CRNDE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in CRNDE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1975
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of RP11-666A20.4 is measured. Determine whether RP11-666A20.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of RP11-666A20.4 is measured. Determine whether RP11-666A20.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4236
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in TMOD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in TMOD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1515
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and EBI3 expression is measured. Determine whether EBI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and EBI3 expression is measured. Determine whether EBI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1659
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in MARCH8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in MARCH8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1435
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and RGS3 expression is measured. Determine whether RGS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and RGS3 expression is measured. Determine whether RGS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2879
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4284
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and S100A11 expression is measured. Determine whether S100A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and S100A11 expression is measured. Determine whether S100A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3259
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in NOX5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in NOX5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3415
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of HIST1H3D. Does perturbing DARS lead to a significant change in HIST1H3D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of HIST1H3D. Does perturbing DARS lead to a significant change in HIST1H3D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":911
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2300
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of DDIT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of DDIT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1827
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in UHRF1BP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in UHRF1BP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":245
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of RPL39. Does this perturbation cause a significant change in RPL39 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of RPL39. Does this perturbation cause a significant change in RPL39 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1744
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of ATP6AP2 is measured. Does this perturbation cause a significant change in ATP6AP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of ATP6AP2 is measured. Does this perturbation cause a significant change in ATP6AP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1620
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in BIRC5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in BIRC5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4505
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in TMEM60 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in TMEM60 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4975
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and FAM212A expression is measured. Determine whether FAM212A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and FAM212A expression is measured. Determine whether FAM212A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2239
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of UHRF1BP1L. Does this perturbation cause a significant change in UHRF1BP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of UHRF1BP1L. Does this perturbation cause a significant change in UHRF1BP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":244
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of RP11-573D15.2. Does perturbing DDOST lead to a significant change in RP11-573D15.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of RP11-573D15.2. Does perturbing DDOST lead to a significant change in RP11-573D15.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3881
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of GUSB. Does this perturbation cause a significant change in GUSB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of GUSB. Does this perturbation cause a significant change in GUSB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1934
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of SPEN. Does perturbing UFM1 lead to a significant change in SPEN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of SPEN. Does perturbing UFM1 lead to a significant change in SPEN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4081
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of BRWD3. Does perturbing DAD1 lead to a significant change in BRWD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of BRWD3. Does perturbing DAD1 lead to a significant change in BRWD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":731
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and SNHG10 expression is measured. Determine whether SNHG10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and SNHG10 expression is measured. Determine whether SNHG10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1319
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and VIM-AS1 expression is observed. Does this perturbation lead to a significant difference in VIM-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and VIM-AS1 expression is observed. Does this perturbation lead to a significant difference in VIM-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1723
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of USP37 is measured. Determine whether USP37 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of USP37 is measured. Determine whether USP37 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1736
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of TLK2. Does perturbing GNPNAT1 lead to a significant change in TLK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of TLK2. Does perturbing GNPNAT1 lead to a significant change in TLK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1991
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and RGS20 expression is measured. Determine whether RGS20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and RGS20 expression is measured. Determine whether RGS20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4949
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of GUSB is measured. Determine whether GUSB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of GUSB is measured. Determine whether GUSB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1936
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of EPS15 is measured. Does this perturbation cause a significant change in EPS15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of EPS15 is measured. Does this perturbation cause a significant change in EPS15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4840
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of PSORS1C1 is measured. Determine whether PSORS1C1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of PSORS1C1 is measured. Determine whether PSORS1C1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2276
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PHF19 expression is quantified. Does this perturbation result in a significant change in PHF19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PHF19 expression is quantified. Does this perturbation result in a significant change in PHF19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3062
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and ACRV1 expression is quantified. Does this perturbation result in a significant change in ACRV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and ACRV1 expression is quantified. Does this perturbation result in a significant change in ACRV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3892
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor TLK2 expression. Decide whether this perturbation leads to a significant alteration in TLK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor TLK2 expression. Decide whether this perturbation leads to a significant alteration in TLK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1998
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of CYP17A1-AS1 is measured. Determine whether CYP17A1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of CYP17A1-AS1 is measured. Determine whether CYP17A1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1246
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor RPL39 expression. Decide whether this perturbation leads to a significant alteration in RPL39 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor RPL39 expression. Decide whether this perturbation leads to a significant alteration in RPL39 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1748
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of S100A11 is measured. Determine whether S100A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of S100A11 is measured. Determine whether S100A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3256
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and LRIF1 expression is quantified. Does this perturbation result in a significant change in LRIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and LRIF1 expression is quantified. Does this perturbation result in a significant change in LRIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1452
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":848
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and TKTL1 expression is measured. Determine whether TKTL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and TKTL1 expression is measured. Determine whether TKTL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":179
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of PLA2G15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of PLA2G15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3837
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and FOXO6 expression is measured. Determine whether FOXO6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and FOXO6 expression is measured. Determine whether FOXO6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4129
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of C17orf64. Does perturbing TIMM44 lead to a significant change in C17orf64 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of C17orf64. Does perturbing TIMM44 lead to a significant change in C17orf64 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3711
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of MYH7B is measured. Does this perturbation cause a significant change in MYH7B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of MYH7B is measured. Does this perturbation cause a significant change in MYH7B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":580
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and IDS expression is measured. Determine whether IDS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and IDS expression is measured. Determine whether IDS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4279
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of SETX is measured. Does this perturbation cause a significant change in SETX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of SETX is measured. Does this perturbation cause a significant change in SETX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2470
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of GRN is measured. Determine whether GRN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of GRN is measured. Determine whether GRN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4336
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of SLC26A1 is measured. Determine whether SLC26A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of SLC26A1 is measured. Determine whether SLC26A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2196
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of KCNE3 is measured. Determine whether KCNE3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of KCNE3 is measured. Determine whether KCNE3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1016
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and DOK3 expression is observed. Does this perturbation lead to a significant difference in DOK3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and DOK3 expression is observed. Does this perturbation lead to a significant difference in DOK3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":263
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and CCDC69 expression is observed. Does this perturbation lead to a significant difference in CCDC69 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and CCDC69 expression is observed. Does this perturbation lead to a significant difference in CCDC69 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3443
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and RP1-274L7.1 expression is observed. Does this perturbation lead to a significant difference in RP1-274L7.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and RP1-274L7.1 expression is observed. Does this perturbation lead to a significant difference in RP1-274L7.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4073
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of NCKAP1L. Does this perturbation cause a significant change in NCKAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of NCKAP1L. Does this perturbation cause a significant change in NCKAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":444
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of TIPARP. Does perturbing EIF2S1 lead to a significant change in TIPARP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of TIPARP. Does perturbing EIF2S1 lead to a significant change in TIPARP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3611
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of CTCFL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of CTCFL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2607
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of HRK is measured. Determine whether HRK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of HRK is measured. Determine whether HRK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1046
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in JUND expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in JUND expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":775
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and PCK2 expression is measured. Determine whether PCK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and PCK2 expression is measured. Determine whether PCK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":339
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of CMTM6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of CMTM6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4917
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor PDK2 expression. Decide whether this perturbation leads to a significant alteration in PDK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor PDK2 expression. Decide whether this perturbation leads to a significant alteration in PDK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2168
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of QSER1. Does perturbing EIF2B2 lead to a significant change in QSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of QSER1. Does perturbing EIF2B2 lead to a significant change in QSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3001
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and PCK2 expression is observed. Does this perturbation lead to a significant difference in PCK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and PCK2 expression is observed. Does this perturbation lead to a significant difference in PCK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":333
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of S100A10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of S100A10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4877
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and PTBP3 expression is quantified. Does this perturbation result in a significant change in PTBP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and PTBP3 expression is quantified. Does this perturbation result in a significant change in PTBP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":662
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RP11-685N10.1 expression is observed. Does this perturbation lead to a significant difference in RP11-685N10.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RP11-685N10.1 expression is observed. Does this perturbation lead to a significant difference in RP11-685N10.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2753
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of DOCK8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of DOCK8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1567
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of PIK3R3. Does perturbing CCND3 lead to a significant change in PIK3R3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of PIK3R3. Does perturbing CCND3 lead to a significant change in PIK3R3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4021
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PSMD14. Does this perturbation cause a significant change in PSMD14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PSMD14. Does this perturbation cause a significant change in PSMD14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3104
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and EBI3 expression is observed. Does this perturbation lead to a significant difference in EBI3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and EBI3 expression is observed. Does this perturbation lead to a significant difference in EBI3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1653
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of SKIL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of SKIL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2947
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of EPS15. Does this perturbation cause a significant change in EPS15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of EPS15. Does this perturbation cause a significant change in EPS15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4844
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of SETX is measured. Determine whether SETX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of SETX is measured. Determine whether SETX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2476
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of CTD-2587M2.1 is measured. Does this perturbation cause a significant change in CTD-2587M2.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of CTD-2587M2.1 is measured. Does this perturbation cause a significant change in CTD-2587M2.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1910
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor CLDN11 expression. Decide whether this perturbation leads to a significant alteration in CLDN11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor CLDN11 expression. Decide whether this perturbation leads to a significant alteration in CLDN11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4548
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and ERV3-1 expression is observed. Does this perturbation lead to a significant difference in ERV3-1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and ERV3-1 expression is observed. Does this perturbation lead to a significant difference in ERV3-1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":463
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor NBEAL2 expression. Decide whether this perturbation leads to a significant alteration in NBEAL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor NBEAL2 expression. Decide whether this perturbation leads to a significant alteration in NBEAL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of ZNF341. Does perturbing PTDSS1 lead to a significant change in ZNF341 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of ZNF341. Does perturbing PTDSS1 lead to a significant change in ZNF341 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3771
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RAI14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RAI14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2705
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and TLN1 expression is quantified. Does this perturbation result in a significant change in TLN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and TLN1 expression is quantified. Does this perturbation result in a significant change in TLN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1032
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of RNF19A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of RNF19A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3767
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of S100A11. Does this perturbation cause a significant change in S100A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of S100A11. Does this perturbation cause a significant change in S100A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4644
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of RP11-435O5.4. Does this perturbation cause a significant change in RP11-435O5.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of RP11-435O5.4. Does this perturbation cause a significant change in RP11-435O5.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1194
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in RP11-863K10.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in RP11-863K10.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":935
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2725
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of PBDC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of PBDC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":607
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in PIK3R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in PIK3R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5105
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of STARD9. Does perturbing COPZ1 lead to a significant change in STARD9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of STARD9. Does perturbing COPZ1 lead to a significant change in STARD9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4601
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and WARS expression is measured. Determine whether WARS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and WARS expression is measured. Determine whether WARS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4889
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of PKDCC. Does this perturbation cause a significant change in PKDCC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of PKDCC. Does this perturbation cause a significant change in PKDCC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1794
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and ZMYND8 expression is quantified. Does this perturbation result in a significant change in ZMYND8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and ZMYND8 expression is quantified. Does this perturbation result in a significant change in ZMYND8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1522
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and EP300 expression is observed. Does this perturbation lead to a significant difference in EP300 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and EP300 expression is observed. Does this perturbation lead to a significant difference in EP300 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2053
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of RP11-430H10.1. Does this perturbation cause a significant change in RP11-430H10.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of RP11-430H10.1. Does this perturbation cause a significant change in RP11-430H10.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5024
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of TRPM4 is measured. Does this perturbation cause a significant change in TRPM4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of TRPM4 is measured. Does this perturbation cause a significant change in TRPM4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3840
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and RP11-499F3.2 expression is observed. Does this perturbation lead to a significant difference in RP11-499F3.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and RP11-499F3.2 expression is observed. Does this perturbation lead to a significant difference in RP11-499F3.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2883
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of IL8. Does perturbing DDRGK1 lead to a significant change in IL8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of IL8. Does perturbing DDRGK1 lead to a significant change in IL8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1251
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and ACE expression is measured. Determine whether ACE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and ACE expression is measured. Determine whether ACE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2579
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in UBE2V1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in UBE2V1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1705
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and MANF expression is measured. Determine whether MANF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and MANF expression is measured. Determine whether MANF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2419
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and HM13 expression is quantified. Does this perturbation result in a significant change in HM13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and HM13 expression is quantified. Does this perturbation result in a significant change in HM13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4512
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and RP11-445H22.3 expression is observed. Does this perturbation lead to a significant difference in RP11-445H22.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and RP11-445H22.3 expression is observed. Does this perturbation lead to a significant difference in RP11-445H22.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3813
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of CFH is measured. Does this perturbation cause a significant change in CFH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of CFH is measured. Does this perturbation cause a significant change in CFH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5050
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of CCDC69 is measured. Does this perturbation cause a significant change in CCDC69 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of CCDC69 is measured. Does this perturbation cause a significant change in CCDC69 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3440
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of MARCH8. Does this perturbation cause a significant change in MARCH8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of MARCH8. Does this perturbation cause a significant change in MARCH8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1434
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of IDS. Does this perturbation cause a significant change in IDS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of IDS. Does this perturbation cause a significant change in IDS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4274
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of RAD51AP1 is measured. Determine whether RAD51AP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of RAD51AP1 is measured. Determine whether RAD51AP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5146
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor RAD51AP1 expression. Decide whether this perturbation leads to a significant alteration in RAD51AP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor RAD51AP1 expression. Decide whether this perturbation leads to a significant alteration in RAD51AP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5148
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":842
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of FAM114A1 is measured. Does this perturbation cause a significant change in FAM114A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of FAM114A1 is measured. Does this perturbation cause a significant change in FAM114A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":710
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and ATP5EP2 expression is observed. Does this perturbation lead to a significant difference in ATP5EP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and ATP5EP2 expression is observed. Does this perturbation lead to a significant difference in ATP5EP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2953
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of RP11-304M2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of RP11-304M2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4537
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of ZNF429 is measured. Determine whether ZNF429 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of ZNF429 is measured. Determine whether ZNF429 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and CPQ expression is quantified. Does this perturbation result in a significant change in CPQ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and CPQ expression is quantified. Does this perturbation result in a significant change in CPQ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2962
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in MT2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in MT2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3165
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and CLINT1 expression is observed. Does this perturbation lead to a significant difference in CLINT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and CLINT1 expression is observed. Does this perturbation lead to a significant difference in CLINT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":433
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and UBE2V1 expression is measured. Determine whether UBE2V1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and UBE2V1 expression is measured. Determine whether UBE2V1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1709
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and PPP4R2 expression is observed. Does this perturbation lead to a significant difference in PPP4R2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and PPP4R2 expression is observed. Does this perturbation lead to a significant difference in PPP4R2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2373
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in SAMM50 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in SAMM50 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":625
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and HIST1H2AM expression is measured. Determine whether HIST1H2AM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and HIST1H2AM expression is measured. Determine whether HIST1H2AM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":389
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and TNFRSF10B expression is observed. Does this perturbation lead to a significant difference in TNFRSF10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and TNFRSF10B expression is observed. Does this perturbation lead to a significant difference in TNFRSF10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3863
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and TSC22D4 expression is quantified. Does this perturbation result in a significant change in TSC22D4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and TSC22D4 expression is quantified. Does this perturbation result in a significant change in TSC22D4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3272
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ZXDA. Does this perturbation cause a significant change in ZXDA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ZXDA. Does this perturbation cause a significant change in ZXDA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3934
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of RP11-95O2.5 is measured. Determine whether RP11-95O2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of RP11-95O2.5 is measured. Determine whether RP11-95O2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4476
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of ADAMTS10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of ADAMTS10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1077
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of IL13RA1 is measured. Does this perturbation cause a significant change in IL13RA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of IL13RA1 is measured. Does this perturbation cause a significant change in IL13RA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2350
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of LIMS1. Does this perturbation cause a significant change in LIMS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of LIMS1. Does this perturbation cause a significant change in LIMS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3374
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in DDIT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in DDIT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1825
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and PCF11 expression is measured. Determine whether PCF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and PCF11 expression is measured. Determine whether PCF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5069
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of TTC32 is measured. Determine whether TTC32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of TTC32 is measured. Determine whether TTC32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3216
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4288
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of NFAT5. Does perturbing GMPPB lead to a significant change in NFAT5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of NFAT5. Does perturbing GMPPB lead to a significant change in NFAT5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1811
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of CLINT1. Does this perturbation cause a significant change in CLINT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of CLINT1. Does this perturbation cause a significant change in CLINT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":434
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of NCKAP1L is measured. Does this perturbation cause a significant change in NCKAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of NCKAP1L is measured. Does this perturbation cause a significant change in NCKAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":440
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of TKTL1. Does this perturbation cause a significant change in TKTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of TKTL1. Does this perturbation cause a significant change in TKTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":174
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of IL18R1 is measured. Does this perturbation cause a significant change in IL18R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of IL18R1 is measured. Does this perturbation cause a significant change in IL18R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":350
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of SDF4. Does this perturbation cause a significant change in SDF4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of SDF4. Does this perturbation cause a significant change in SDF4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1774
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of ZNF292. Does this perturbation cause a significant change in ZNF292 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of ZNF292. Does this perturbation cause a significant change in ZNF292 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1504
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of STK17B. Does perturbing XRN1 lead to a significant change in STK17B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of STK17B. Does perturbing XRN1 lead to a significant change in STK17B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4851
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of APOL4 is measured. Does this perturbation cause a significant change in APOL4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of APOL4 is measured. Does this perturbation cause a significant change in APOL4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":890
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and SPEN expression is measured. Determine whether SPEN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and SPEN expression is measured. Determine whether SPEN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1579
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in POLR2J3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in POLR2J3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3795
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor GS1-166A23.1 expression. Decide whether this perturbation leads to a significant alteration in GS1-166A23.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor GS1-166A23.1 expression. Decide whether this perturbation leads to a significant alteration in GS1-166A23.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3298
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ZXDA expression. Decide whether this perturbation leads to a significant alteration in ZXDA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ZXDA expression. Decide whether this perturbation leads to a significant alteration in ZXDA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3938
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in CHD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in CHD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4905
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor AC015987.1 expression. Decide whether this perturbation leads to a significant alteration in AC015987.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor AC015987.1 expression. Decide whether this perturbation leads to a significant alteration in AC015987.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2258
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor PGM3 expression. Decide whether this perturbation leads to a significant alteration in PGM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor PGM3 expression. Decide whether this perturbation leads to a significant alteration in PGM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2088
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and HIST1H2BC expression is measured. Determine whether HIST1H2BC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and HIST1H2BC expression is measured. Determine whether HIST1H2BC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4779
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor RP11-138C9.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-138C9.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor RP11-138C9.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-138C9.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":838
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of RP3-465N24.6. Does perturbing SRP68 lead to a significant change in RP3-465N24.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of RP3-465N24.6. Does perturbing SRP68 lead to a significant change in RP3-465N24.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3581
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and HMGCS1 expression is quantified. Does this perturbation result in a significant change in HMGCS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and HMGCS1 expression is quantified. Does this perturbation result in a significant change in HMGCS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":372
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and PGM3 expression is measured. Determine whether PGM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and PGM3 expression is measured. Determine whether PGM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2089
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of TOPBP1 is measured. Does this perturbation cause a significant change in TOPBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of TOPBP1 is measured. Does this perturbation cause a significant change in TOPBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3800
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of UBE3A is measured. Determine whether UBE3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of UBE3A is measured. Determine whether UBE3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1226
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and NFAT5 expression is quantified. Does this perturbation result in a significant change in NFAT5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and NFAT5 expression is quantified. Does this perturbation result in a significant change in NFAT5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1812
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in TFPI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in TFPI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3915
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of PGM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of PGM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2087
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and CHST12 expression is observed. Does this perturbation lead to a significant difference in CHST12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and CHST12 expression is observed. Does this perturbation lead to a significant difference in CHST12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3463
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and SLBP expression is quantified. Does this perturbation result in a significant change in SLBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and SLBP expression is quantified. Does this perturbation result in a significant change in SLBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2132
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of ARHGAP6. Does this perturbation cause a significant change in ARHGAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of ARHGAP6. Does this perturbation cause a significant change in ARHGAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1754
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and SRP72 expression is measured. Determine whether SRP72 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and SRP72 expression is measured. Determine whether SRP72 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1239
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and TOPBP1 expression is measured. Determine whether TOPBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and TOPBP1 expression is measured. Determine whether TOPBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2899
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of VIMP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of VIMP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":977
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of IRF7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of IRF7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":537
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor NUFIP2 expression. Decide whether this perturbation leads to a significant alteration in NUFIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor NUFIP2 expression. Decide whether this perturbation leads to a significant alteration in NUFIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2468
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor P4HA2 expression. Decide whether this perturbation leads to a significant alteration in P4HA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor P4HA2 expression. Decide whether this perturbation leads to a significant alteration in P4HA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2408
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and HIST1H1D expression is measured. Determine whether HIST1H1D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and HIST1H1D expression is measured. Determine whether HIST1H1D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4349
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and USP37 expression is quantified. Does this perturbation result in a significant change in USP37 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and USP37 expression is quantified. Does this perturbation result in a significant change in USP37 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1732
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of CDCA3. Does perturbing UFM1 lead to a significant change in CDCA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of CDCA3. Does perturbing UFM1 lead to a significant change in CDCA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4111
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of AFF1. Does perturbing TARS lead to a significant change in AFF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of AFF1. Does perturbing TARS lead to a significant change in AFF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2911
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and P4HA2 expression is measured. Determine whether P4HA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and P4HA2 expression is measured. Determine whether P4HA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor SMCO1 expression. Decide whether this perturbation leads to a significant alteration in SMCO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor SMCO1 expression. Decide whether this perturbation leads to a significant alteration in SMCO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4498
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of NFE2L3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of NFE2L3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4827
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of NFE2. Does perturbing DDIT3 lead to a significant change in NFE2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of NFE2. Does perturbing DDIT3 lead to a significant change in NFE2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":211
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of UHMK1 is measured. Does this perturbation cause a significant change in UHMK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of UHMK1 is measured. Does this perturbation cause a significant change in UHMK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4980
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of ANKRD10. Does this perturbation cause a significant change in ANKRD10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of ANKRD10. Does this perturbation cause a significant change in ANKRD10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4354
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in DOK3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in DOK3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":265
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in MORF4L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in MORF4L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2625
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of LINC00938. Does perturbing UFM1 lead to a significant change in LINC00938 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of LINC00938. Does perturbing UFM1 lead to a significant change in LINC00938 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4101
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4578
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of NINJ2 is measured. Does this perturbation cause a significant change in NINJ2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of NINJ2 is measured. Does this perturbation cause a significant change in NINJ2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2140
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor RSAD2 expression. Decide whether this perturbation leads to a significant alteration in RSAD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor RSAD2 expression. Decide whether this perturbation leads to a significant alteration in RSAD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1468
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and HPCAL1 expression is measured. Determine whether HPCAL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and HPCAL1 expression is measured. Determine whether HPCAL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2979
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and RP11-227G15.8 expression is quantified. Does this perturbation result in a significant change in RP11-227G15.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and RP11-227G15.8 expression is quantified. Does this perturbation result in a significant change in RP11-227G15.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2932
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of ANKRD33. Does this perturbation cause a significant change in ANKRD33 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of ANKRD33. Does this perturbation cause a significant change in ANKRD33 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4184
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and SKIL expression is observed. Does this perturbation lead to a significant difference in SKIL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and SKIL expression is observed. Does this perturbation lead to a significant difference in SKIL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2943
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of SPINK5 is measured. Does this perturbation cause a significant change in SPINK5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of SPINK5 is measured. Does this perturbation cause a significant change in SPINK5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":410
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and RGS20 expression is measured. Determine whether RGS20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and RGS20 expression is measured. Determine whether RGS20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3129
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of RP11-95O2.5. Does perturbing PPWD1 lead to a significant change in RP11-95O2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of RP11-95O2.5. Does perturbing PPWD1 lead to a significant change in RP11-95O2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4471
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and ANXA4 expression is observed. Does this perturbation lead to a significant difference in ANXA4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and ANXA4 expression is observed. Does this perturbation lead to a significant difference in ANXA4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":743
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and NFE2L3 expression is measured. Determine whether NFE2L3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and NFE2L3 expression is measured. Determine whether NFE2L3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1589
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and DDIT4 expression is observed. Does this perturbation lead to a significant difference in DDIT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and DDIT4 expression is observed. Does this perturbation lead to a significant difference in DDIT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1823
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor CTC-308K20.1 expression. Decide whether this perturbation leads to a significant alteration in CTC-308K20.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor CTC-308K20.1 expression. Decide whether this perturbation leads to a significant alteration in CTC-308K20.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5138
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of PLB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of PLB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4957
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and C6orf48 expression is measured. Determine whether C6orf48 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and C6orf48 expression is measured. Determine whether C6orf48 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in APOBEC3D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in APOBEC3D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3575
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of UFD1L. Does perturbing GBF1 lead to a significant change in UFD1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of UFD1L. Does perturbing GBF1 lead to a significant change in UFD1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2501
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and GNPTG expression is observed. Does this perturbation lead to a significant difference in GNPTG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and GNPTG expression is observed. Does this perturbation lead to a significant difference in GNPTG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3093
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and NOSTRIN expression is measured. Determine whether NOSTRIN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and NOSTRIN expression is measured. Determine whether NOSTRIN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4329
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of AC007038.7. Does this perturbation cause a significant change in AC007038.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of AC007038.7. Does this perturbation cause a significant change in AC007038.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2924
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and KIAA0922 expression is quantified. Does this perturbation result in a significant change in KIAA0922 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and KIAA0922 expression is quantified. Does this perturbation result in a significant change in KIAA0922 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3742
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and RP11-434H6.6 expression is measured. Determine whether RP11-434H6.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and RP11-434H6.6 expression is measured. Determine whether RP11-434H6.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1899
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of RP11-61E11.1 is measured. Does this perturbation cause a significant change in RP11-61E11.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of RP11-61E11.1 is measured. Does this perturbation cause a significant change in RP11-61E11.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1420
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and TNFRSF10B expression is quantified. Does this perturbation result in a significant change in TNFRSF10B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and TNFRSF10B expression is quantified. Does this perturbation result in a significant change in TNFRSF10B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2282
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor RBM12B-AS1 expression. Decide whether this perturbation leads to a significant alteration in RBM12B-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor RBM12B-AS1 expression. Decide whether this perturbation leads to a significant alteration in RBM12B-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2518
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and ABI2 expression is observed. Does this perturbation lead to a significant difference in ABI2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and ABI2 expression is observed. Does this perturbation lead to a significant difference in ABI2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2023
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and PPM1N expression is quantified. Does this perturbation result in a significant change in PPM1N expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and PPM1N expression is quantified. Does this perturbation result in a significant change in PPM1N expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3922
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of HLTF is measured. Determine whether HLTF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of HLTF is measured. Determine whether HLTF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2486
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in NCKAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in NCKAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":445
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and RP11-789C1.1 expression is quantified. Does this perturbation result in a significant change in RP11-789C1.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and RP11-789C1.1 expression is quantified. Does this perturbation result in a significant change in RP11-789C1.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":942
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of NRIP1 is measured. Does this perturbation cause a significant change in NRIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of NRIP1 is measured. Does this perturbation cause a significant change in NRIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of CELF6. Does perturbing P4HB lead to a significant change in CELF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of CELF6. Does perturbing P4HB lead to a significant change in CELF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5031
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and SETX expression is measured. Determine whether SETX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and SETX expression is measured. Determine whether SETX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2479
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of PRRC2B. Does this perturbation cause a significant change in PRRC2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of PRRC2B. Does this perturbation cause a significant change in PRRC2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":904
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in CTSV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in CTSV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2675
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of PDK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of PDK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2167
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RP11-685N10.1 is measured. Determine whether RP11-685N10.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RP11-685N10.1 is measured. Determine whether RP11-685N10.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2756
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and SLC25A35 expression is quantified. Does this perturbation result in a significant change in SLC25A35 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and SLC25A35 expression is quantified. Does this perturbation result in a significant change in SLC25A35 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3152
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and RIMS3 expression is quantified. Does this perturbation result in a significant change in RIMS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and RIMS3 expression is quantified. Does this perturbation result in a significant change in RIMS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":162
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of ZCCHC11 is measured. Determine whether ZCCHC11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of ZCCHC11 is measured. Determine whether ZCCHC11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4996
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of RP11-132A1.4. Does perturbing DAD1 lead to a significant change in RP11-132A1.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of RP11-132A1.4. Does perturbing DAD1 lead to a significant change in RP11-132A1.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":721
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and RAD51AP1 expression is measured. Determine whether RAD51AP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and RAD51AP1 expression is measured. Determine whether RAD51AP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5149
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and ARHGAP11A expression is observed. Does this perturbation lead to a significant difference in ARHGAP11A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and ARHGAP11A expression is observed. Does this perturbation lead to a significant difference in ARHGAP11A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3723
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and KIAA0922 expression is measured. Determine whether KIAA0922 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and KIAA0922 expression is measured. Determine whether KIAA0922 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3749
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of KCNJ13. Does this perturbation cause a significant change in KCNJ13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of KCNJ13. Does this perturbation cause a significant change in KCNJ13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3654
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in LRRC4B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in LRRC4B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2175
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and ZP3 expression is measured. Determine whether ZP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and ZP3 expression is measured. Determine whether ZP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2549
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of EIF4B is measured. Determine whether EIF4B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of EIF4B is measured. Determine whether EIF4B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4966
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of PPP1R16B. Does perturbing PPWD1 lead to a significant change in PPP1R16B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of PPP1R16B. Does perturbing PPWD1 lead to a significant change in PPP1R16B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4481
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of RP11-334C17.5 is measured. Does this perturbation cause a significant change in RP11-334C17.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of RP11-334C17.5 is measured. Does this perturbation cause a significant change in RP11-334C17.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1000
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of GUSB. Does perturbing SAMM50 lead to a significant change in GUSB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of GUSB. Does perturbing SAMM50 lead to a significant change in GUSB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1401
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of MORC2-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of MORC2-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2557
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor SLBP expression. Decide whether this perturbation leads to a significant alteration in SLBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor SLBP expression. Decide whether this perturbation leads to a significant alteration in SLBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2138
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in PIK3R3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in PIK3R3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4025
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of WARS is measured. Does this perturbation cause a significant change in WARS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of WARS is measured. Does this perturbation cause a significant change in WARS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4880
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and IL2RB expression is observed. Does this perturbation lead to a significant difference in IL2RB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and IL2RB expression is observed. Does this perturbation lead to a significant difference in IL2RB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3603
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and RP11-2H8.2 expression is observed. Does this perturbation lead to a significant difference in RP11-2H8.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and RP11-2H8.2 expression is observed. Does this perturbation lead to a significant difference in RP11-2H8.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3593
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor UQCRB expression. Decide whether this perturbation leads to a significant alteration in UQCRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor UQCRB expression. Decide whether this perturbation leads to a significant alteration in UQCRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":708
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and RSAD2 expression is measured. Determine whether RSAD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and RSAD2 expression is measured. Determine whether RSAD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1469
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in EP300 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in EP300 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1685
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in PHF21A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in PHF21A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3855
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and RAD51AP1 expression is observed. Does this perturbation lead to a significant difference in RAD51AP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and RAD51AP1 expression is observed. Does this perturbation lead to a significant difference in RAD51AP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5143
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of LTB is measured. Determine whether LTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of LTB is measured. Determine whether LTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":326
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of RILPL2. Does perturbing HSD17B12 lead to a significant change in RILPL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of RILPL2. Does perturbing HSD17B12 lead to a significant change in RILPL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2801
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of CTD-2001C12.1 is measured. Determine whether CTD-2001C12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of CTD-2001C12.1 is measured. Determine whether CTD-2001C12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":576
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of SETX. Does perturbing SRP72 lead to a significant change in SETX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of SETX. Does perturbing SRP72 lead to a significant change in SETX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3361
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of PHF3 is measured. Does this perturbation cause a significant change in PHF3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of PHF3 is measured. Does this perturbation cause a significant change in PHF3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":80
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of HERC2 is measured. Does this perturbation cause a significant change in HERC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of HERC2 is measured. Does this perturbation cause a significant change in HERC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":950
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of PIK3R1. Does perturbing SPCS2 lead to a significant change in PIK3R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of PIK3R1. Does perturbing SPCS2 lead to a significant change in PIK3R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5101
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor ANKRD33 expression. Decide whether this perturbation leads to a significant alteration in ANKRD33 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor ANKRD33 expression. Decide whether this perturbation leads to a significant alteration in ANKRD33 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4188
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and PIK3R1 expression is observed. Does this perturbation lead to a significant difference in PIK3R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and PIK3R1 expression is observed. Does this perturbation lead to a significant difference in PIK3R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5103
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and PKDCC expression is quantified. Does this perturbation result in a significant change in PKDCC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and PKDCC expression is quantified. Does this perturbation result in a significant change in PKDCC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1792
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and GPR146 expression is quantified. Does this perturbation result in a significant change in GPR146 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and GPR146 expression is quantified. Does this perturbation result in a significant change in GPR146 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5082
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of LINC00862 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of LINC00862 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4597
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of KANSL1L is measured. Determine whether KANSL1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of KANSL1L is measured. Determine whether KANSL1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":646
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ZP3 expression is quantified. Does this perturbation result in a significant change in ZP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ZP3 expression is quantified. Does this perturbation result in a significant change in ZP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2542
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of KIAA0922. Does this perturbation cause a significant change in KIAA0922 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of KIAA0922. Does this perturbation cause a significant change in KIAA0922 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3744
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in ACSM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in ACSM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2215
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of EIF4B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of EIF4B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4967
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and RSAD2 expression is measured. Determine whether RSAD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and RSAD2 expression is measured. Determine whether RSAD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4409
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of RP11-838N2.4 is measured. Determine whether RP11-838N2.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of RP11-838N2.4 is measured. Determine whether RP11-838N2.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3036
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and KIAA1432 expression is measured. Determine whether KIAA1432 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and KIAA1432 expression is measured. Determine whether KIAA1432 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3759
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of LINC01031 is measured. Does this perturbation cause a significant change in LINC01031 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of LINC01031 is measured. Does this perturbation cause a significant change in LINC01031 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4240
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of KLF6 is measured. Determine whether KLF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of KLF6 is measured. Determine whether KLF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2296
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of ERV3-1 is measured. Determine whether ERV3-1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of ERV3-1 is measured. Determine whether ERV3-1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":466
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and RILPL2 expression is measured. Determine whether RILPL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and RILPL2 expression is measured. Determine whether RILPL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4149
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and SOBP expression is quantified. Does this perturbation result in a significant change in SOBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and SOBP expression is quantified. Does this perturbation result in a significant change in SOBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3632
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ARHGAP6 is measured. Does this perturbation cause a significant change in ARHGAP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ARHGAP6 is measured. Does this perturbation cause a significant change in ARHGAP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3900
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RIOK3 expression is measured. Determine whether RIOK3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RIOK3 expression is measured. Determine whether RIOK3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and TRIM38 expression is observed. Does this perturbation lead to a significant difference in TRIM38 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and TRIM38 expression is observed. Does this perturbation lead to a significant difference in TRIM38 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3383
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor NPDC1 expression. Decide whether this perturbation leads to a significant alteration in NPDC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor NPDC1 expression. Decide whether this perturbation leads to a significant alteration in NPDC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1328
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of MORF4L2. Does perturbing SEC63 lead to a significant change in MORF4L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of MORF4L2. Does perturbing SEC63 lead to a significant change in MORF4L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2621
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of RP11-95O2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of RP11-95O2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4477
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of PTBP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of PTBP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":667
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in RP11-254F7.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in RP11-254F7.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2395
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ZFP36L2. Does perturbing KCTD16 lead to a significant change in ZFP36L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ZFP36L2. Does perturbing KCTD16 lead to a significant change in ZFP36L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3451
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and SRP72 expression is quantified. Does this perturbation result in a significant change in SRP72 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and SRP72 expression is quantified. Does this perturbation result in a significant change in SRP72 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1232
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and RILPL2 expression is measured. Determine whether RILPL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and RILPL2 expression is measured. Determine whether RILPL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2809
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of RP11-212I21.4 is measured. Does this perturbation cause a significant change in RP11-212I21.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of RP11-212I21.4 is measured. Does this perturbation cause a significant change in RP11-212I21.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2030
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in NUFIP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in NUFIP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2465
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in RASGRP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in RASGRP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4265
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in WHAMM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in WHAMM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":785
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of PSORS1C1. Does this perturbation cause a significant change in PSORS1C1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of PSORS1C1. Does this perturbation cause a significant change in PSORS1C1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2274
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of AC096559.1. Does perturbing CAD lead to a significant change in AC096559.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of AC096559.1. Does perturbing CAD lead to a significant change in AC096559.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1871
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of NPAT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of NPAT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3327
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of RP11-227G15.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of RP11-227G15.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2937
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of LAMP2. Does perturbing SPCS3 lead to a significant change in LAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of LAMP2. Does perturbing SPCS3 lead to a significant change in LAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5041
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3508
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of HLTF. Does this perturbation cause a significant change in HLTF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of HLTF. Does this perturbation cause a significant change in HLTF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2484
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of MS4A6E is measured. Does this perturbation cause a significant change in MS4A6E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of MS4A6E is measured. Does this perturbation cause a significant change in MS4A6E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":340
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor RP11-15E18.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-15E18.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor RP11-15E18.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-15E18.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4058
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and CELF6 expression is quantified. Does this perturbation result in a significant change in CELF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and CELF6 expression is quantified. Does this perturbation result in a significant change in CELF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5032
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and WHAMM expression is measured. Determine whether WHAMM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and WHAMM expression is measured. Determine whether WHAMM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":789
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of CDCA3. Does this perturbation cause a significant change in CDCA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of CDCA3. Does this perturbation cause a significant change in CDCA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4114
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of RP11-423O2.5 is measured. Determine whether RP11-423O2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of RP11-423O2.5 is measured. Determine whether RP11-423O2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":306
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of POLR2J3 is measured. Does this perturbation cause a significant change in POLR2J3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of POLR2J3 is measured. Does this perturbation cause a significant change in POLR2J3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3790
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and NPAT expression is measured. Determine whether NPAT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and NPAT expression is measured. Determine whether NPAT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3329
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RGS20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RGS20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2715
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in GLG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in GLG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1945
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3964
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of ZNF292 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of ZNF292 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1507
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor RP11-3D4.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-3D4.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor RP11-3D4.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-3D4.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3648
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of HM13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of HM13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4517
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and DYNC1H1 expression is observed. Does this perturbation lead to a significant difference in DYNC1H1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and DYNC1H1 expression is observed. Does this perturbation lead to a significant difference in DYNC1H1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3143
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in HERC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in HERC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":955
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of DSC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of DSC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4097
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and C6orf120 expression is measured. Determine whether C6orf120 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and C6orf120 expression is measured. Determine whether C6orf120 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2269
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor CD46 expression. Decide whether this perturbation leads to a significant alteration in CD46 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor CD46 expression. Decide whether this perturbation leads to a significant alteration in CD46 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4218
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of TIPARP is measured. Does this perturbation cause a significant change in TIPARP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of TIPARP is measured. Does this perturbation cause a significant change in TIPARP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3610
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of AC015987.2 is measured. Determine whether AC015987.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of AC015987.2 is measured. Determine whether AC015987.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2016
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of GS1-166A23.1 is measured. Determine whether GS1-166A23.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of GS1-166A23.1 is measured. Determine whether GS1-166A23.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3296
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of QSER1 is measured. Does this perturbation cause a significant change in QSER1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of QSER1 is measured. Does this perturbation cause a significant change in QSER1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3000
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of LINC01031. Does this perturbation cause a significant change in LINC01031 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of LINC01031. Does this perturbation cause a significant change in LINC01031 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4244
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of TROAP is measured. Determine whether TROAP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of TROAP is measured. Determine whether TROAP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3086
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of FGF11 is measured. Does this perturbation cause a significant change in FGF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of FGF11 is measured. Does this perturbation cause a significant change in FGF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4170
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of LINC00938. Does this perturbation cause a significant change in LINC00938 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of LINC00938. Does this perturbation cause a significant change in LINC00938 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4104
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RAI14 is measured. Determine whether RAI14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RAI14 is measured. Determine whether RAI14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2706
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of DDX3X indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of DDX3X indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1087
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in SETX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in SETX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3365
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor TTC18 expression. Decide whether this perturbation leads to a significant alteration in TTC18 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor TTC18 expression. Decide whether this perturbation leads to a significant alteration in TTC18 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3698
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of CASP4. Does this perturbation cause a significant change in CASP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of CASP4. Does this perturbation cause a significant change in CASP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of HLA-E is measured. Does this perturbation cause a significant change in HLA-E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of HLA-E is measured. Does this perturbation cause a significant change in HLA-E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3260
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor S100A10 expression. Decide whether this perturbation leads to a significant alteration in S100A10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor S100A10 expression. Decide whether this perturbation leads to a significant alteration in S100A10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4878
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and ZNF429 expression is measured. Determine whether ZNF429 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and ZNF429 expression is measured. Determine whether ZNF429 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in S100A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in S100A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4645
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of PPP1R16B. Does perturbing YIPF5 lead to a significant change in PPP1R16B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of PPP1R16B. Does perturbing YIPF5 lead to a significant change in PPP1R16B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":591
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and RP11-430H10.1 expression is observed. Does this perturbation lead to a significant difference in RP11-430H10.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and RP11-430H10.1 expression is observed. Does this perturbation lead to a significant difference in RP11-430H10.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5023
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of ZCCHC11 is measured. Does this perturbation cause a significant change in ZCCHC11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of ZCCHC11 is measured. Does this perturbation cause a significant change in ZCCHC11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4990
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in NFE2L3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in NFE2L3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4825
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and GRN expression is observed. Does this perturbation lead to a significant difference in GRN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and GRN expression is observed. Does this perturbation lead to a significant difference in GRN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4333
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of TOB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of TOB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":987
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of RP11-15E18.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of RP11-15E18.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4057
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of IDS is measured. Does this perturbation cause a significant change in IDS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of IDS is measured. Does this perturbation cause a significant change in IDS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4270
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of C6orf48 is measured. Does this perturbation cause a significant change in C6orf48 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of C6orf48 is measured. Does this perturbation cause a significant change in C6orf48 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of ITGB2. Does perturbing QARS lead to a significant change in ITGB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of ITGB2. Does perturbing QARS lead to a significant change in ITGB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1301
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in CEBPG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in CEBPG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of HOTAIRM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of HOTAIRM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1267
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and PELO expression is quantified. Does this perturbation result in a significant change in PELO expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and PELO expression is quantified. Does this perturbation result in a significant change in PELO expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3982
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of PCK2 is measured. Determine whether PCK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of PCK2 is measured. Determine whether PCK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3016
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and PITPNB expression is measured. Determine whether PITPNB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and PITPNB expression is measured. Determine whether PITPNB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3739
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor HIST1H1D expression. Decide whether this perturbation leads to a significant alteration in HIST1H1D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor HIST1H1D expression. Decide whether this perturbation leads to a significant alteration in HIST1H1D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4348
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor RNF139-AS1 expression. Decide whether this perturbation leads to a significant alteration in RNF139-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor RNF139-AS1 expression. Decide whether this perturbation leads to a significant alteration in RNF139-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2528
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of MARCH8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of MARCH8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1437
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of PGM3 is measured. Determine whether PGM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of PGM3 is measured. Determine whether PGM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2086
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of C19orf59. Does this perturbation cause a significant change in C19orf59 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of C19orf59. Does this perturbation cause a significant change in C19orf59 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2344
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and PDRG1 expression is quantified. Does this perturbation result in a significant change in PDRG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and PDRG1 expression is quantified. Does this perturbation result in a significant change in PDRG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4152
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of ZFHX3. Does perturbing AARS lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of ZFHX3. Does perturbing AARS lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4281
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of ARSA is measured. Determine whether ARSA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of ARSA is measured. Determine whether ARSA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":686
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of SPEN is measured. Determine whether SPEN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of SPEN is measured. Determine whether SPEN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4086
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor ATP11B expression. Decide whether this perturbation leads to a significant alteration in ATP11B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor ATP11B expression. Decide whether this perturbation leads to a significant alteration in ATP11B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":298
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of KLK1 is measured. Does this perturbation cause a significant change in KLK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of KLK1 is measured. Does this perturbation cause a significant change in KLK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":200
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor RP11-227G15.8 expression. Decide whether this perturbation leads to a significant alteration in RP11-227G15.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor RP11-227G15.8 expression. Decide whether this perturbation leads to a significant alteration in RP11-227G15.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2938
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of IDH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of IDH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2647
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of MS4A6E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of MS4A6E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":347
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and PTPN11 expression is observed. Does this perturbation lead to a significant difference in PTPN11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and PTPN11 expression is observed. Does this perturbation lead to a significant difference in PTPN11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":503
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of MEX3B is measured. Determine whether MEX3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of MEX3B is measured. Determine whether MEX3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":676
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and RNF8 expression is observed. Does this perturbation lead to a significant difference in RNF8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and RNF8 expression is observed. Does this perturbation lead to a significant difference in RNF8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3183
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and CTNNB1 expression is observed. Does this perturbation lead to a significant difference in CTNNB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and CTNNB1 expression is observed. Does this perturbation lead to a significant difference in CTNNB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2453
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and RNF139-AS1 expression is observed. Does this perturbation lead to a significant difference in RNF139-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and RNF139-AS1 expression is observed. Does this perturbation lead to a significant difference in RNF139-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2523
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and LDLR expression is observed. Does this perturbation lead to a significant difference in LDLR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and LDLR expression is observed. Does this perturbation lead to a significant difference in LDLR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":493
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of RP11-838N2.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of RP11-838N2.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3037
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of GNPTG. Does perturbing SARS lead to a significant change in GNPTG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of GNPTG. Does perturbing SARS lead to a significant change in GNPTG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3091
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of GUSB is measured. Does this perturbation cause a significant change in GUSB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of GUSB is measured. Does this perturbation cause a significant change in GUSB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1400
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of GATA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of GATA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":887
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of RP11-322J23.1 is measured. Does this perturbation cause a significant change in RP11-322J23.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of RP11-322J23.1 is measured. Does this perturbation cause a significant change in RP11-322J23.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4720
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of THBS1. Does perturbing P4HB lead to a significant change in THBS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of THBS1. Does perturbing P4HB lead to a significant change in THBS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5011
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in RDH10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in RDH10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":145
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ARHGAP5 expression is measured. Determine whether ARHGAP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ARHGAP5 expression is measured. Determine whether ARHGAP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3439
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor TACC3 expression. Decide whether this perturbation leads to a significant alteration in TACC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor TACC3 expression. Decide whether this perturbation leads to a significant alteration in TACC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1868
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of AC008074.3 is measured. Does this perturbation cause a significant change in AC008074.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of AC008074.3 is measured. Does this perturbation cause a significant change in AC008074.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1900
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2534
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of FAM212A is measured. Determine whether FAM212A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of FAM212A is measured. Determine whether FAM212A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2236
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of QSER1 is measured. Does this perturbation cause a significant change in QSER1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of QSER1 is measured. Does this perturbation cause a significant change in QSER1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5000
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and CDK13 expression is observed. Does this perturbation lead to a significant difference in CDK13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and CDK13 expression is observed. Does this perturbation lead to a significant difference in CDK13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2763
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of WHAMM. Does this perturbation cause a significant change in WHAMM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of WHAMM. Does this perturbation cause a significant change in WHAMM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":784
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and CD83 expression is measured. Determine whether CD83 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and CD83 expression is measured. Determine whether CD83 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2699
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of HERPUD1 is measured. Determine whether HERPUD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of HERPUD1 is measured. Determine whether HERPUD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4436
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor LTB expression. Decide whether this perturbation leads to a significant alteration in LTB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor LTB expression. Decide whether this perturbation leads to a significant alteration in LTB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4708
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor FCGRT expression. Decide whether this perturbation leads to a significant alteration in FCGRT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor FCGRT expression. Decide whether this perturbation leads to a significant alteration in FCGRT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3538
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of RP11-789C1.1 is measured. Determine whether RP11-789C1.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of RP11-789C1.1 is measured. Determine whether RP11-789C1.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":946
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and SNHG7 expression is observed. Does this perturbation lead to a significant difference in SNHG7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and SNHG7 expression is observed. Does this perturbation lead to a significant difference in SNHG7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4043
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of PELO. Does this perturbation cause a significant change in PELO expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of PELO. Does this perturbation cause a significant change in PELO expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2114
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of DNASE2. Does this perturbation cause a significant change in DNASE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of DNASE2. Does this perturbation cause a significant change in DNASE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1634
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and GOT1 expression is quantified. Does this perturbation result in a significant change in GOT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and GOT1 expression is quantified. Does this perturbation result in a significant change in GOT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1112
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and GALNT7 expression is quantified. Does this perturbation result in a significant change in GALNT7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and GALNT7 expression is quantified. Does this perturbation result in a significant change in GALNT7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4382
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor CMTM6 expression. Decide whether this perturbation leads to a significant alteration in CMTM6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor CMTM6 expression. Decide whether this perturbation leads to a significant alteration in CMTM6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4918
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1132
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in ERV3-1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in ERV3-1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":465
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and AC007038.7 expression is measured. Determine whether AC007038.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and AC007038.7 expression is measured. Determine whether AC007038.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2929
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of PBDC1. Does this perturbation cause a significant change in PBDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of PBDC1. Does this perturbation cause a significant change in PBDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":604
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RGS20 expression is quantified. Does this perturbation result in a significant change in RGS20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RGS20 expression is quantified. Does this perturbation result in a significant change in RGS20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2712
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and SEPT5 expression is measured. Determine whether SEPT5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and SEPT5 expression is measured. Determine whether SEPT5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3549
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and P4HB expression is measured. Determine whether P4HB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and P4HB expression is measured. Determine whether P4HB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4619
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of SERPINH1 is measured. Does this perturbation cause a significant change in SERPINH1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of SERPINH1 is measured. Does this perturbation cause a significant change in SERPINH1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1640
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of QSER1. Does this perturbation cause a significant change in QSER1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of QSER1. Does this perturbation cause a significant change in QSER1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4684
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor SBF2 expression. Decide whether this perturbation leads to a significant alteration in SBF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor SBF2 expression. Decide whether this perturbation leads to a significant alteration in SBF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2568
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of HERPUD1. Does this perturbation cause a significant change in HERPUD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of HERPUD1. Does this perturbation cause a significant change in HERPUD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4434
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of DST is measured. Does this perturbation cause a significant change in DST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of DST is measured. Does this perturbation cause a significant change in DST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3490
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of KIAA1586 is measured. Does this perturbation cause a significant change in KIAA1586 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of KIAA1586 is measured. Does this perturbation cause a significant change in KIAA1586 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4650
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and CENPC expression is quantified. Does this perturbation result in a significant change in CENPC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and CENPC expression is quantified. Does this perturbation result in a significant change in CENPC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4452
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of PCK2 is measured. Does this perturbation cause a significant change in PCK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of PCK2 is measured. Does this perturbation cause a significant change in PCK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3010
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of RCBTB2. Does perturbing STT3A lead to a significant change in RCBTB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of RCBTB2. Does perturbing STT3A lead to a significant change in RCBTB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1331
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and KIAA1586 expression is measured. Determine whether KIAA1586 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and KIAA1586 expression is measured. Determine whether KIAA1586 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4659
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor VIMP expression. Decide whether this perturbation leads to a significant alteration in VIMP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor VIMP expression. Decide whether this perturbation leads to a significant alteration in VIMP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":978
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of DNASE2 is measured. Does this perturbation cause a significant change in DNASE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of DNASE2 is measured. Does this perturbation cause a significant change in DNASE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1630
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in RP11-95O2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in RP11-95O2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4475
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of DUSP21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of DUSP21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2747
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor UBE3A expression. Decide whether this perturbation leads to a significant alteration in UBE3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor UBE3A expression. Decide whether this perturbation leads to a significant alteration in UBE3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1228
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of C10orf32 is measured. Does this perturbation cause a significant change in C10orf32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of C10orf32 is measured. Does this perturbation cause a significant change in C10orf32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3040
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in RP11-146D12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in RP11-146D12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":475
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and NPAT expression is quantified. Does this perturbation result in a significant change in NPAT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and NPAT expression is quantified. Does this perturbation result in a significant change in NPAT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3322
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and LINC01137 expression is quantified. Does this perturbation result in a significant change in LINC01137 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and LINC01137 expression is quantified. Does this perturbation result in a significant change in LINC01137 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4662
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of RP11-157D23.2. Does this perturbation cause a significant change in RP11-157D23.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of RP11-157D23.2. Does this perturbation cause a significant change in RP11-157D23.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4424
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and PDRG1 expression is measured. Determine whether PDRG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and PDRG1 expression is measured. Determine whether PDRG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4159
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of RP11-242O24.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of RP11-242O24.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3997
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and HLA-AS1 expression is measured. Determine whether HLA-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and HLA-AS1 expression is measured. Determine whether HLA-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":769
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and RP11-242O24.5 expression is quantified. Does this perturbation result in a significant change in RP11-242O24.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and RP11-242O24.5 expression is quantified. Does this perturbation result in a significant change in RP11-242O24.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3992
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of SNHG12. Does perturbing AMIGO3 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of SNHG12. Does perturbing AMIGO3 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":841
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor FGF11 expression. Decide whether this perturbation leads to a significant alteration in FGF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor FGF11 expression. Decide whether this perturbation leads to a significant alteration in FGF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4178
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of EP400 is measured. Does this perturbation cause a significant change in EP400 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of EP400 is measured. Does this perturbation cause a significant change in EP400 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3660
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and EP300 expression is measured. Determine whether EP300 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and EP300 expression is measured. Determine whether EP300 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2059
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in NTRK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in NTRK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4035
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3505
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and GALNT7 expression is observed. Does this perturbation lead to a significant difference in GALNT7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and GALNT7 expression is observed. Does this perturbation lead to a significant difference in GALNT7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4383
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor GATA2 expression. Decide whether this perturbation leads to a significant alteration in GATA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor GATA2 expression. Decide whether this perturbation leads to a significant alteration in GATA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5118
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of RGS20 is measured. Determine whether RGS20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of RGS20 is measured. Determine whether RGS20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4946
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of SPAST is measured. Determine whether SPAST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of SPAST is measured. Determine whether SPAST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":926
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of EPB42 is measured. Determine whether EPB42 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of EPB42 is measured. Determine whether EPB42 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1716
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of CPQ. Does perturbing ASCC3 lead to a significant change in CPQ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of CPQ. Does perturbing ASCC3 lead to a significant change in CPQ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2961
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of C1GALT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of C1GALT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2007
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of C6orf120 is measured. Determine whether C6orf120 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of C6orf120 is measured. Determine whether C6orf120 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2266
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and ACRV1 expression is observed. Does this perturbation lead to a significant difference in ACRV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and ACRV1 expression is observed. Does this perturbation lead to a significant difference in ACRV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3893
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of RP11-499F3.2. Does this perturbation cause a significant change in RP11-499F3.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of RP11-499F3.2. Does this perturbation cause a significant change in RP11-499F3.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2884
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in PRRC2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in PRRC2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":905
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in EP400 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in EP400 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3665
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of KCNH7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of KCNH7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1787
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor CELF6 expression. Decide whether this perturbation leads to a significant alteration in CELF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor CELF6 expression. Decide whether this perturbation leads to a significant alteration in CELF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5038
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of TFPI is measured. Does this perturbation cause a significant change in TFPI expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of TFPI is measured. Does this perturbation cause a significant change in TFPI expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3910
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2049
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of RP11-390B4.5. Does this perturbation cause a significant change in RP11-390B4.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of RP11-390B4.5. Does this perturbation cause a significant change in RP11-390B4.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4834
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of MARCH8. Does perturbing SAMM50 lead to a significant change in MARCH8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of MARCH8. Does perturbing SAMM50 lead to a significant change in MARCH8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1431
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2785
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and GNPTG expression is quantified. Does this perturbation result in a significant change in GNPTG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and GNPTG expression is quantified. Does this perturbation result in a significant change in GNPTG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3092
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor PRRC2B expression. Decide whether this perturbation leads to a significant alteration in PRRC2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor PRRC2B expression. Decide whether this perturbation leads to a significant alteration in PRRC2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":908
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of VPS41 is measured. Does this perturbation cause a significant change in VPS41 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of VPS41 is measured. Does this perturbation cause a significant change in VPS41 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":630
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of RILPL2 is measured. Does this perturbation cause a significant change in RILPL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of RILPL2 is measured. Does this perturbation cause a significant change in RILPL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4140
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of DUT is measured. Determine whether DUT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of DUT is measured. Determine whether DUT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":276
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of PLB1 is measured. Determine whether PLB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of PLB1 is measured. Determine whether PLB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4956
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and PDE3B expression is measured. Determine whether PDE3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and PDE3B expression is measured. Determine whether PDE3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4789
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of CD83 is measured. Determine whether CD83 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of CD83 is measured. Determine whether CD83 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2696
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of RP11-573D15.9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of RP11-573D15.9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1297
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of SAMM50 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of SAMM50 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":627
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of NFAT5. Does this perturbation cause a significant change in NFAT5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of NFAT5. Does this perturbation cause a significant change in NFAT5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1814
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of FGF11 is measured. Determine whether FGF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of FGF11 is measured. Determine whether FGF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4176
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in SEC23IP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in SEC23IP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3975
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and LPAR5 expression is measured. Determine whether LPAR5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and LPAR5 expression is measured. Determine whether LPAR5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and VPS41 expression is measured. Determine whether VPS41 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and VPS41 expression is measured. Determine whether VPS41 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":639
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RGS20 is measured. Does this perturbation cause a significant change in RGS20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RGS20 is measured. Does this perturbation cause a significant change in RGS20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2710
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of CFH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of CFH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5057
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and PELO expression is quantified. Does this perturbation result in a significant change in PELO expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and PELO expression is quantified. Does this perturbation result in a significant change in PELO expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2112
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of CDT1. Does this perturbation cause a significant change in CDT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of CDT1. Does this perturbation cause a significant change in CDT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5124
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor DDX6 expression. Decide whether this perturbation leads to a significant alteration in DDX6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor DDX6 expression. Decide whether this perturbation leads to a significant alteration in DDX6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":528
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of KCNJ13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of KCNJ13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3657
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of TUBA1C is measured. Does this perturbation cause a significant change in TUBA1C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of TUBA1C is measured. Does this perturbation cause a significant change in TUBA1C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3390
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and C19orf59 expression is observed. Does this perturbation lead to a significant difference in C19orf59 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and C19orf59 expression is observed. Does this perturbation lead to a significant difference in C19orf59 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2343
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor IL18R1 expression. Decide whether this perturbation leads to a significant alteration in IL18R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor IL18R1 expression. Decide whether this perturbation leads to a significant alteration in IL18R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":358
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of MORC2-AS1. Does perturbing FARSB lead to a significant change in MORC2-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of MORC2-AS1. Does perturbing FARSB lead to a significant change in MORC2-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2551
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and BAMBI expression is measured. Determine whether BAMBI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and BAMBI expression is measured. Determine whether BAMBI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1179
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and DUSP21 expression is observed. Does this perturbation lead to a significant difference in DUSP21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and DUSP21 expression is observed. Does this perturbation lead to a significant difference in DUSP21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2743
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of ARHGAP6 is measured. Does this perturbation cause a significant change in ARHGAP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of ARHGAP6 is measured. Does this perturbation cause a significant change in ARHGAP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1750
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and RP11-90P5.2 expression is observed. Does this perturbation lead to a significant difference in RP11-90P5.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and RP11-90P5.2 expression is observed. Does this perturbation lead to a significant difference in RP11-90P5.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":403
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of TOB2 is measured. Determine whether TOB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of TOB2 is measured. Determine whether TOB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":986
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of PSMC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of PSMC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2827
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of SDF4. Does perturbing MTHFD1 lead to a significant change in SDF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of SDF4. Does perturbing MTHFD1 lead to a significant change in SDF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1771
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of EBI3 is measured. Determine whether EBI3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of EBI3 is measured. Determine whether EBI3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1656
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in HIST1H1E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in HIST1H1E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1025
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4577
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and UQCRB expression is quantified. Does this perturbation result in a significant change in UQCRB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and UQCRB expression is quantified. Does this perturbation result in a significant change in UQCRB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":702
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and ATF6 expression is observed. Does this perturbation lead to a significant difference in ATF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and ATF6 expression is observed. Does this perturbation lead to a significant difference in ATF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":853
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and NFE2L3 expression is observed. Does this perturbation lead to a significant difference in NFE2L3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and NFE2L3 expression is observed. Does this perturbation lead to a significant difference in NFE2L3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4823
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of QSER1. Does perturbing SEC61G lead to a significant change in QSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of QSER1. Does perturbing SEC61G lead to a significant change in QSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4681
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor SNHG7 expression. Decide whether this perturbation leads to a significant alteration in SNHG7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor SNHG7 expression. Decide whether this perturbation leads to a significant alteration in SNHG7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4048
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and DST expression is observed. Does this perturbation lead to a significant difference in DST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and DST expression is observed. Does this perturbation lead to a significant difference in DST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3493
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of GNPTG is measured. Does this perturbation cause a significant change in GNPTG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of GNPTG is measured. Does this perturbation cause a significant change in GNPTG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3090
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of SEPT5 is measured. Determine whether SEPT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of SEPT5 is measured. Determine whether SEPT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3546
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of IL8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of IL8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1257
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of IL18R1. Does this perturbation cause a significant change in IL18R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of IL18R1. Does this perturbation cause a significant change in IL18R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4204
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of PCF11. Does perturbing SPCS3 lead to a significant change in PCF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of PCF11. Does perturbing SPCS3 lead to a significant change in PCF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5061
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of VIMP is measured. Does this perturbation cause a significant change in VIMP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of VIMP is measured. Does this perturbation cause a significant change in VIMP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":970
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of ARHGAP6. Does perturbing MTHFD1 lead to a significant change in ARHGAP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of ARHGAP6. Does perturbing MTHFD1 lead to a significant change in ARHGAP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1751
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of SP100 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of SP100 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1147
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of BOLA3. Does perturbing EIF2B3 lead to a significant change in BOLA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of BOLA3. Does perturbing EIF2B3 lead to a significant change in BOLA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4631
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of PDE4D is measured. Does this perturbation cause a significant change in PDE4D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of PDE4D is measured. Does this perturbation cause a significant change in PDE4D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":510
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of CTSV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of CTSV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2677
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor AP000688.8 expression. Decide whether this perturbation leads to a significant alteration in AP000688.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor AP000688.8 expression. Decide whether this perturbation leads to a significant alteration in AP000688.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3338
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of PTBP3 is measured. Does this perturbation cause a significant change in PTBP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of PTBP3 is measured. Does this perturbation cause a significant change in PTBP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":660
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of KANSL1L. Does perturbing HARS lead to a significant change in KANSL1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of KANSL1L. Does perturbing HARS lead to a significant change in KANSL1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":641
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and LBX1 expression is observed. Does this perturbation lead to a significant difference in LBX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and LBX1 expression is observed. Does this perturbation lead to a significant difference in LBX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1593
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and STC2 expression is observed. Does this perturbation lead to a significant difference in STC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and STC2 expression is observed. Does this perturbation lead to a significant difference in STC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":183
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of LTB. Does perturbing SEC61A1 lead to a significant change in LTB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of LTB. Does perturbing SEC61A1 lead to a significant change in LTB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":321
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and BOLA3 expression is measured. Determine whether BOLA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and BOLA3 expression is measured. Determine whether BOLA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4639
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2539
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and COPB1 expression is quantified. Does this perturbation result in a significant change in COPB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and COPB1 expression is quantified. Does this perturbation result in a significant change in COPB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":802
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and RP11-328J2.1 expression is observed. Does this perturbation lead to a significant difference in RP11-328J2.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and RP11-328J2.1 expression is observed. Does this perturbation lead to a significant difference in RP11-328J2.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1093
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of EIF3A is measured. Determine whether EIF3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of EIF3A is measured. Determine whether EIF3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4806
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor ADAMTS10 expression. Decide whether this perturbation leads to a significant alteration in ADAMTS10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor ADAMTS10 expression. Decide whether this perturbation leads to a significant alteration in ADAMTS10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1078
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and GATA2 expression is quantified. Does this perturbation result in a significant change in GATA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and GATA2 expression is quantified. Does this perturbation result in a significant change in GATA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5112
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor BOLA3 expression. Decide whether this perturbation leads to a significant alteration in BOLA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor BOLA3 expression. Decide whether this perturbation leads to a significant alteration in BOLA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4638
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of ATF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of ATF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":857
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor ATXN7L3B expression. Decide whether this perturbation leads to a significant alteration in ATXN7L3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor ATXN7L3B expression. Decide whether this perturbation leads to a significant alteration in ATXN7L3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4938
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and CDK13 expression is measured. Determine whether CDK13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and CDK13 expression is measured. Determine whether CDK13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2769
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor TOPBP1 expression. Decide whether this perturbation leads to a significant alteration in TOPBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor TOPBP1 expression. Decide whether this perturbation leads to a significant alteration in TOPBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2898
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of RP11-430H10.1 is measured. Does this perturbation cause a significant change in RP11-430H10.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of RP11-430H10.1 is measured. Does this perturbation cause a significant change in RP11-430H10.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5020
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of CDK13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of CDK13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2767
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in KIAA0922 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in KIAA0922 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3745
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor CTBS expression. Decide whether this perturbation leads to a significant alteration in CTBS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor CTBS expression. Decide whether this perturbation leads to a significant alteration in CTBS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4448
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of BACH2 is measured. Does this perturbation cause a significant change in BACH2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of BACH2 is measured. Does this perturbation cause a significant change in BACH2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3470
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of HPCAL1. Does perturbing ASCC3 lead to a significant change in HPCAL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of HPCAL1. Does perturbing ASCC3 lead to a significant change in HPCAL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2971
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in P4HA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in P4HA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2405
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and CTC-550B14.7 expression is observed. Does this perturbation lead to a significant difference in CTC-550B14.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and CTC-550B14.7 expression is observed. Does this perturbation lead to a significant difference in CTC-550B14.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4553
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of TAP1 is measured. Determine whether TAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of TAP1 is measured. Determine whether TAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4716
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of MANF. Does this perturbation cause a significant change in MANF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of MANF. Does this perturbation cause a significant change in MANF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2414
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in AMOTL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in AMOTL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2245
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of NFE2L3. Does this perturbation cause a significant change in NFE2L3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of NFE2L3. Does this perturbation cause a significant change in NFE2L3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4824
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of RP11-390B4.5. Does perturbing XRN1 lead to a significant change in RP11-390B4.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of RP11-390B4.5. Does perturbing XRN1 lead to a significant change in RP11-390B4.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4831
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in HAGH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in HAGH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2635
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and MED13 expression is quantified. Does this perturbation result in a significant change in MED13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and MED13 expression is quantified. Does this perturbation result in a significant change in MED13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4312
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and RDH10 expression is observed. Does this perturbation lead to a significant difference in RDH10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and RDH10 expression is observed. Does this perturbation lead to a significant difference in RDH10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":143
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of PIK3R1. Does this perturbation cause a significant change in PIK3R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of PIK3R1. Does this perturbation cause a significant change in PIK3R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5104
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of KIAA1731 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of KIAA1731 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4897
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and SKIL expression is quantified. Does this perturbation result in a significant change in SKIL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and SKIL expression is quantified. Does this perturbation result in a significant change in SKIL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2942
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and RP11-146D12.2 expression is quantified. Does this perturbation result in a significant change in RP11-146D12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and RP11-146D12.2 expression is quantified. Does this perturbation result in a significant change in RP11-146D12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":472
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PIF1 is measured. Determine whether PIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PIF1 is measured. Determine whether PIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3076
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in VPS41 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in VPS41 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":635
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":846
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and LINC01031 expression is observed. Does this perturbation lead to a significant difference in LINC01031 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and LINC01031 expression is observed. Does this perturbation lead to a significant difference in LINC01031 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4243
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and PCK2 expression is quantified. Does this perturbation result in a significant change in PCK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and PCK2 expression is quantified. Does this perturbation result in a significant change in PCK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3012
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and EP400 expression is measured. Determine whether EP400 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and EP400 expression is measured. Determine whether EP400 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3669
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and IL18R1 expression is quantified. Does this perturbation result in a significant change in IL18R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and IL18R1 expression is quantified. Does this perturbation result in a significant change in IL18R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4202
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor THBS1 expression. Decide whether this perturbation leads to a significant alteration in THBS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor THBS1 expression. Decide whether this perturbation leads to a significant alteration in THBS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5018
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of RP11-322J23.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of RP11-322J23.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4727
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in ARHGAP11A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in ARHGAP11A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3725
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of CTC-550B14.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of CTC-550B14.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4557
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor HIST1H3D expression. Decide whether this perturbation leads to a significant alteration in HIST1H3D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor HIST1H3D expression. Decide whether this perturbation leads to a significant alteration in HIST1H3D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":918
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of CENPF is measured. Determine whether CENPF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of CENPF is measured. Determine whether CENPF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4066
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in LINC00657 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in LINC00657 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":255
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor PTGS1 expression. Decide whether this perturbation leads to a significant alteration in PTGS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor PTGS1 expression. Decide whether this perturbation leads to a significant alteration in PTGS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3488
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of RTN2 is measured. Does this perturbation cause a significant change in RTN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of RTN2 is measured. Does this perturbation cause a significant change in RTN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2060
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor CLDN11 expression. Decide whether this perturbation leads to a significant alteration in CLDN11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor CLDN11 expression. Decide whether this perturbation leads to a significant alteration in CLDN11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2618
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of PIK3R3 is measured. Determine whether PIK3R3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of PIK3R3 is measured. Determine whether PIK3R3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4026
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of GPR146. Does perturbing SPCS3 lead to a significant change in GPR146 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of GPR146. Does perturbing SPCS3 lead to a significant change in GPR146 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5081
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and KHDC1L expression is quantified. Does this perturbation result in a significant change in KHDC1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and KHDC1L expression is quantified. Does this perturbation result in a significant change in KHDC1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1062
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor MED13 expression. Decide whether this perturbation leads to a significant alteration in MED13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor MED13 expression. Decide whether this perturbation leads to a significant alteration in MED13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4318
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and SERPING1 expression is observed. Does this perturbation lead to a significant difference in SERPING1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and SERPING1 expression is observed. Does this perturbation lead to a significant difference in SERPING1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3243
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and PLA2G15 expression is observed. Does this perturbation lead to a significant difference in PLA2G15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and PLA2G15 expression is observed. Does this perturbation lead to a significant difference in PLA2G15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3833
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and EIF4B expression is quantified. Does this perturbation result in a significant change in EIF4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and EIF4B expression is quantified. Does this perturbation result in a significant change in EIF4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4962
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of ATP6AP2. Does this perturbation cause a significant change in ATP6AP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of ATP6AP2. Does this perturbation cause a significant change in ATP6AP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1624
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in C12orf23 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in C12orf23 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1765
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of APOBEC3D is measured. Determine whether APOBEC3D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of APOBEC3D is measured. Determine whether APOBEC3D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3576
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of TRIM38 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of TRIM38 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3387
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of MEX3B. Does perturbing SLMO2 lead to a significant change in MEX3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of MEX3B. Does perturbing SLMO2 lead to a significant change in MEX3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":671
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in RP11-81A22.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in RP11-81A22.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1615
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor HAGH expression. Decide whether this perturbation leads to a significant alteration in HAGH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor HAGH expression. Decide whether this perturbation leads to a significant alteration in HAGH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2638
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of COPB1. Does perturbing TIMM23 lead to a significant change in COPB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of COPB1. Does perturbing TIMM23 lead to a significant change in COPB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":801
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and RSL24D1 expression is measured. Determine whether RSL24D1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and RSL24D1 expression is measured. Determine whether RSL24D1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":879
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PSMD14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PSMD14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3107
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of ANPEP is measured. Determine whether ANPEP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of ANPEP is measured. Determine whether ANPEP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4796
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of ARSA. Does this perturbation cause a significant change in ARSA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of ARSA. Does this perturbation cause a significant change in ARSA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":684
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of RP11-430H10.1 is measured. Determine whether RP11-430H10.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of RP11-430H10.1 is measured. Determine whether RP11-430H10.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5026
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of TRIM24 is measured. Determine whether TRIM24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of TRIM24 is measured. Determine whether TRIM24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3196
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of OR2T6 is measured. Determine whether OR2T6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of OR2T6 is measured. Determine whether OR2T6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1846
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3967
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of SPINK5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of SPINK5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":417
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of ATF7IP2 is measured. Does this perturbation cause a significant change in ATF7IP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of ATF7IP2 is measured. Does this perturbation cause a significant change in ATF7IP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4520
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of PELO is measured. Determine whether PELO shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of PELO is measured. Determine whether PELO shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3986
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and HLA-E expression is observed. Does this perturbation lead to a significant difference in HLA-E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and HLA-E expression is observed. Does this perturbation lead to a significant difference in HLA-E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3263
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of RP11-157D23.2. Does perturbing FECH lead to a significant change in RP11-157D23.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of RP11-157D23.2. Does perturbing FECH lead to a significant change in RP11-157D23.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4421
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of AMOTL1. Does this perturbation cause a significant change in AMOTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of AMOTL1. Does this perturbation cause a significant change in AMOTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2244
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in HLA-E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in HLA-E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3265
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and DNASE2 expression is measured. Determine whether DNASE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and DNASE2 expression is measured. Determine whether DNASE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1639
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor IFNGR1 expression. Decide whether this perturbation leads to a significant alteration in IFNGR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor IFNGR1 expression. Decide whether this perturbation leads to a significant alteration in IFNGR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2658
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3507
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and PCK2 expression is observed. Does this perturbation lead to a significant difference in PCK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and PCK2 expression is observed. Does this perturbation lead to a significant difference in PCK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3013
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of YTHDF2. Does perturbing TMED2 lead to a significant change in YTHDF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of YTHDF2. Does perturbing TMED2 lead to a significant change in YTHDF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4921
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and MLEC expression is measured. Determine whether MLEC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and MLEC expression is measured. Determine whether MLEC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3179
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of NUFIP2 is measured. Determine whether NUFIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of NUFIP2 is measured. Determine whether NUFIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2466
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and CTCFL expression is observed. Does this perturbation lead to a significant difference in CTCFL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and CTCFL expression is observed. Does this perturbation lead to a significant difference in CTCFL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2603
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of VIM-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of VIM-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1727
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and CTD-2001C12.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2001C12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and CTD-2001C12.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2001C12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":573
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of ATP2A3. Does perturbing GMPPB lead to a significant change in ATP2A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of ATP2A3. Does perturbing GMPPB lead to a significant change in ATP2A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1831
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of GSN is measured. Determine whether GSN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of GSN is measured. Determine whether GSN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3206
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of NAV1. Does perturbing PPWD1 lead to a significant change in NAV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of NAV1. Does perturbing PPWD1 lead to a significant change in NAV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4461
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of VIMP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of VIMP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4587
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of SERPING1. Does perturbing HSPA5 lead to a significant change in SERPING1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of SERPING1. Does perturbing HSPA5 lead to a significant change in SERPING1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3241
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of SERPINH1. Does perturbing ATP5B lead to a significant change in SERPINH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of SERPINH1. Does perturbing ATP5B lead to a significant change in SERPINH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1641
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of IL2RB is measured. Does this perturbation cause a significant change in IL2RB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of IL2RB is measured. Does this perturbation cause a significant change in IL2RB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3600
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of NSD1. Does this perturbation cause a significant change in NSD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of NSD1. Does this perturbation cause a significant change in NSD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1344
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and RP11-15E18.1 expression is observed. Does this perturbation lead to a significant difference in RP11-15E18.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and RP11-15E18.1 expression is observed. Does this perturbation lead to a significant difference in RP11-15E18.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4053
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and RP11-863K10.7 expression is measured. Determine whether RP11-863K10.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and RP11-863K10.7 expression is measured. Determine whether RP11-863K10.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":939
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and ARSA expression is measured. Determine whether ARSA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and ARSA expression is measured. Determine whether ARSA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":689
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of FGF11. Does perturbing COPB1 lead to a significant change in FGF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of FGF11. Does perturbing COPB1 lead to a significant change in FGF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4171
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of RNF139-AS1. Does this perturbation cause a significant change in RNF139-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of RNF139-AS1. Does this perturbation cause a significant change in RNF139-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2524
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of GLG1. Does perturbing TMEM167A lead to a significant change in GLG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of GLG1. Does perturbing TMEM167A lead to a significant change in GLG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1941
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and KHDC1L expression is measured. Determine whether KHDC1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and KHDC1L expression is measured. Determine whether KHDC1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1069
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PSMD14. Does perturbing SARS lead to a significant change in PSMD14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PSMD14. Does perturbing SARS lead to a significant change in PSMD14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3101
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of RP11-435O5.4. Does perturbing UFL1 lead to a significant change in RP11-435O5.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of RP11-435O5.4. Does perturbing UFL1 lead to a significant change in RP11-435O5.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1191
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of TXNIP. Does perturbing TMED10 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of TXNIP. Does perturbing TMED10 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3961
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of PPM1N indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of PPM1N indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3927
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and RASGRP2 expression is observed. Does this perturbation lead to a significant difference in RASGRP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and RASGRP2 expression is observed. Does this perturbation lead to a significant difference in RASGRP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4263
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of SSBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of SSBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4167
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of CD83. Does this perturbation cause a significant change in CD83 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of CD83. Does this perturbation cause a significant change in CD83 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2694
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in MS4A6E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in MS4A6E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":345
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and TLK2 expression is observed. Does this perturbation lead to a significant difference in TLK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and TLK2 expression is observed. Does this perturbation lead to a significant difference in TLK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1993
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of PKDCC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of PKDCC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1797
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of AC096559.1 is measured. Does this perturbation cause a significant change in AC096559.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of AC096559.1 is measured. Does this perturbation cause a significant change in AC096559.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1870
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of ANKRD11. Does perturbing SEC61G lead to a significant change in ANKRD11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of ANKRD11. Does perturbing SEC61G lead to a significant change in ANKRD11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4691
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and ATAD2B expression is observed. Does this perturbation lead to a significant difference in ATAD2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and ATAD2B expression is observed. Does this perturbation lead to a significant difference in ATAD2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4393
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in H3F3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in H3F3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2325
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor PELO expression. Decide whether this perturbation leads to a significant alteration in PELO expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor PELO expression. Decide whether this perturbation leads to a significant alteration in PELO expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3988
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in ZNF292 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in ZNF292 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1505
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of BAMBI. Does this perturbation cause a significant change in BAMBI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of BAMBI. Does this perturbation cause a significant change in BAMBI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1174
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and GPRC5C expression is observed. Does this perturbation lead to a significant difference in GPRC5C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and GPRC5C expression is observed. Does this perturbation lead to a significant difference in GPRC5C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2223
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of ANKRD33 is measured. Does this perturbation cause a significant change in ANKRD33 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of ANKRD33 is measured. Does this perturbation cause a significant change in ANKRD33 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4180
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and HERC2 expression is quantified. Does this perturbation result in a significant change in HERC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and HERC2 expression is quantified. Does this perturbation result in a significant change in HERC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":952
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and ATP2A3 expression is quantified. Does this perturbation result in a significant change in ATP2A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and ATP2A3 expression is quantified. Does this perturbation result in a significant change in ATP2A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1832
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and NSD1 expression is quantified. Does this perturbation result in a significant change in NSD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and NSD1 expression is quantified. Does this perturbation result in a significant change in NSD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1342
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in TSC22D4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in TSC22D4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3275
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of EBI3. Does perturbing ATP5B lead to a significant change in EBI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of EBI3. Does perturbing ATP5B lead to a significant change in EBI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1651
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3504
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of SERPING1 is measured. Does this perturbation cause a significant change in SERPING1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of SERPING1 is measured. Does this perturbation cause a significant change in SERPING1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3240
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of RP11-435O5.4 is measured. Does this perturbation cause a significant change in RP11-435O5.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of RP11-435O5.4 is measured. Does this perturbation cause a significant change in RP11-435O5.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1190
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of PKDCC is measured. Determine whether PKDCC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of PKDCC is measured. Determine whether PKDCC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1796
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and VIMP expression is observed. Does this perturbation lead to a significant difference in VIMP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and VIMP expression is observed. Does this perturbation lead to a significant difference in VIMP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4583
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and RAD51AP1 expression is quantified. Does this perturbation result in a significant change in RAD51AP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and RAD51AP1 expression is quantified. Does this perturbation result in a significant change in RAD51AP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5142
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and LINC01137 expression is measured. Determine whether LINC01137 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and LINC01137 expression is measured. Determine whether LINC01137 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4669
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and PDE4D expression is observed. Does this perturbation lead to a significant difference in PDE4D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and PDE4D expression is observed. Does this perturbation lead to a significant difference in PDE4D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":513
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor CPQ expression. Decide whether this perturbation leads to a significant alteration in CPQ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor CPQ expression. Decide whether this perturbation leads to a significant alteration in CPQ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2968
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of IFNGR1. Does this perturbation cause a significant change in IFNGR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of IFNGR1. Does this perturbation cause a significant change in IFNGR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2654
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in SP100 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in SP100 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1145
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and ARHGDIB expression is measured. Determine whether ARHGDIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and ARHGDIB expression is measured. Determine whether ARHGDIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1969
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in GUSB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in GUSB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1935
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in CCDC69 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in CCDC69 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3445
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor APOBEC3D expression. Decide whether this perturbation leads to a significant alteration in APOBEC3D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor APOBEC3D expression. Decide whether this perturbation leads to a significant alteration in APOBEC3D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3578
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of TAGLN. Does this perturbation cause a significant change in TAGLN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of TAGLN. Does this perturbation cause a significant change in TAGLN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1354
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and ZCCHC11 expression is measured. Determine whether ZCCHC11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and ZCCHC11 expression is measured. Determine whether ZCCHC11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4999
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor YTHDF2 expression. Decide whether this perturbation leads to a significant alteration in YTHDF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor YTHDF2 expression. Decide whether this perturbation leads to a significant alteration in YTHDF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4928
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1134
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor ZNF429 expression. Decide whether this perturbation leads to a significant alteration in ZNF429 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor ZNF429 expression. Decide whether this perturbation leads to a significant alteration in ZNF429 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor MEX3B expression. Decide whether this perturbation leads to a significant alteration in MEX3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor MEX3B expression. Decide whether this perturbation leads to a significant alteration in MEX3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":678
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of MORF4L2 is measured. Does this perturbation cause a significant change in MORF4L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of MORF4L2 is measured. Does this perturbation cause a significant change in MORF4L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2620
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of RP11-247A12.2. Does this perturbation cause a significant change in RP11-247A12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of RP11-247A12.2. Does this perturbation cause a significant change in RP11-247A12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1664
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and OXLD1 expression is quantified. Does this perturbation result in a significant change in OXLD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and OXLD1 expression is quantified. Does this perturbation result in a significant change in OXLD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2852
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in KLK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in KLK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":205
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of PDE4D. Does this perturbation cause a significant change in PDE4D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of PDE4D. Does this perturbation cause a significant change in PDE4D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":514
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of APOBEC3D. Does this perturbation cause a significant change in APOBEC3D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of APOBEC3D. Does this perturbation cause a significant change in APOBEC3D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3574
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of KIAA1432. Does this perturbation cause a significant change in KIAA1432 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of KIAA1432. Does this perturbation cause a significant change in KIAA1432 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3754
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ZXDA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ZXDA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3937
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of ACRV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of ACRV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3897
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and C6orf120 expression is quantified. Does this perturbation result in a significant change in C6orf120 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and C6orf120 expression is quantified. Does this perturbation result in a significant change in C6orf120 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2262
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of RP11-363D14.1. Does perturbing EIF2B2 lead to a significant change in RP11-363D14.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of RP11-363D14.1. Does perturbing EIF2B2 lead to a significant change in RP11-363D14.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3051
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of STARD9 is measured. Does this perturbation cause a significant change in STARD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of STARD9 is measured. Does this perturbation cause a significant change in STARD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4600
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4755
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of AC015987.2. Does perturbing GNPNAT1 lead to a significant change in AC015987.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of AC015987.2. Does perturbing GNPNAT1 lead to a significant change in AC015987.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2011
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of RP11-24F11.2 is measured. Does this perturbation cause a significant change in RP11-24F11.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of RP11-24F11.2 is measured. Does this perturbation cause a significant change in RP11-24F11.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1490
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and EIF3A expression is quantified. Does this perturbation result in a significant change in EIF3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and EIF3A expression is quantified. Does this perturbation result in a significant change in EIF3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4802
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and SBF2 expression is quantified. Does this perturbation result in a significant change in SBF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and SBF2 expression is quantified. Does this perturbation result in a significant change in SBF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2562
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and SEPT5 expression is quantified. Does this perturbation result in a significant change in SEPT5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and SEPT5 expression is quantified. Does this perturbation result in a significant change in SEPT5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3542
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor PIK3R3 expression. Decide whether this perturbation leads to a significant alteration in PIK3R3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor PIK3R3 expression. Decide whether this perturbation leads to a significant alteration in PIK3R3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4028
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of STC2 is measured. Determine whether STC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of STC2 is measured. Determine whether STC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":186
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and RP11-360L9.8 expression is quantified. Does this perturbation result in a significant change in RP11-360L9.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and RP11-360L9.8 expression is quantified. Does this perturbation result in a significant change in RP11-360L9.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4292
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and JUND expression is observed. Does this perturbation lead to a significant difference in JUND expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and JUND expression is observed. Does this perturbation lead to a significant difference in JUND expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":773
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor CD58 expression. Decide whether this perturbation leads to a significant alteration in CD58 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor CD58 expression. Decide whether this perturbation leads to a significant alteration in CD58 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2498
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and CYP17A1-AS1 expression is measured. Determine whether CYP17A1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and CYP17A1-AS1 expression is measured. Determine whether CYP17A1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1249
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and SPAST expression is measured. Determine whether SPAST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and SPAST expression is measured. Determine whether SPAST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":929
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of C17orf64 is measured. Determine whether C17orf64 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of C17orf64 is measured. Determine whether C17orf64 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3716
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in PBDC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in PBDC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":605
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of TMOD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of TMOD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1517
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of RP11-304M2.5 is measured. Determine whether RP11-304M2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of RP11-304M2.5 is measured. Determine whether RP11-304M2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4536
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of DYNC1H1 is measured. Determine whether DYNC1H1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of DYNC1H1 is measured. Determine whether DYNC1H1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3146
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of GATA3. Does this perturbation cause a significant change in GATA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of GATA3. Does this perturbation cause a significant change in GATA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":884
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3960
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of SETX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of SETX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3367
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and NCKAP1L expression is measured. Determine whether NCKAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and NCKAP1L expression is measured. Determine whether NCKAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":449
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and AC008074.3 expression is observed. Does this perturbation lead to a significant difference in AC008074.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and AC008074.3 expression is observed. Does this perturbation lead to a significant difference in AC008074.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1903
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of KIAA1432 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of KIAA1432 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3757
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of COPB1. Does this perturbation cause a significant change in COPB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of COPB1. Does this perturbation cause a significant change in COPB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":804
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and LAMP2 expression is observed. Does this perturbation lead to a significant difference in LAMP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and LAMP2 expression is observed. Does this perturbation lead to a significant difference in LAMP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5043
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in RNF8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in RNF8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3185
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and LDLR expression is quantified. Does this perturbation result in a significant change in LDLR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and LDLR expression is quantified. Does this perturbation result in a significant change in LDLR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":492
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of WDR72. Does perturbing UFM1 lead to a significant change in WDR72 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of WDR72. Does perturbing UFM1 lead to a significant change in WDR72 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4131
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of GPRC5C is measured. Does this perturbation cause a significant change in GPRC5C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of GPRC5C is measured. Does this perturbation cause a significant change in GPRC5C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2220
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of RP11-146D12.2. Does perturbing SRPR lead to a significant change in RP11-146D12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of RP11-146D12.2. Does perturbing SRPR lead to a significant change in RP11-146D12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":471
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of LINC00862 is measured. Determine whether LINC00862 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of LINC00862 is measured. Determine whether LINC00862 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4596
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and CLDN11 expression is observed. Does this perturbation lead to a significant difference in CLDN11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and CLDN11 expression is observed. Does this perturbation lead to a significant difference in CLDN11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2613
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ARHGAP5 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ARHGAP5 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3438
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of DNMBP. Does this perturbation cause a significant change in DNMBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of DNMBP. Does this perturbation cause a significant change in DNMBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4014
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of POLR2J3. Does perturbing HYOU1 lead to a significant change in POLR2J3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of POLR2J3. Does perturbing HYOU1 lead to a significant change in POLR2J3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3791
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PSMD14 expression is observed. Does this perturbation lead to a significant difference in PSMD14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PSMD14 expression is observed. Does this perturbation lead to a significant difference in PSMD14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3103
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of BRWD3. Does this perturbation cause a significant change in BRWD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of BRWD3. Does this perturbation cause a significant change in BRWD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":734
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of HLA-E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of HLA-E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3267
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ZFP36L2 expression is measured. Determine whether ZFP36L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ZFP36L2 expression is measured. Determine whether ZFP36L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3459
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and ASPM expression is observed. Does this perturbation lead to a significant difference in ASPM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and ASPM expression is observed. Does this perturbation lead to a significant difference in ASPM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2663
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and SLC37A1 expression is quantified. Does this perturbation result in a significant change in SLC37A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and SLC37A1 expression is quantified. Does this perturbation result in a significant change in SLC37A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1152
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2098
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of CEBPG is measured. Does this perturbation cause a significant change in CEBPG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of CEBPG is measured. Does this perturbation cause a significant change in CEBPG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of GPR146. Does this perturbation cause a significant change in GPR146 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of GPR146. Does this perturbation cause a significant change in GPR146 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5084
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of CDKN2C. Does perturbing HSD17B12 lead to a significant change in CDKN2C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of CDKN2C. Does perturbing HSD17B12 lead to a significant change in CDKN2C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2811
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in BACH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in BACH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3475
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and RP11-16E12.1 expression is observed. Does this perturbation lead to a significant difference in RP11-16E12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and RP11-16E12.1 expression is observed. Does this perturbation lead to a significant difference in RP11-16E12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3233
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of EXO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of EXO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2837
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in PDE4D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in PDE4D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":515
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and AMOTL1 expression is measured. Determine whether AMOTL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and AMOTL1 expression is measured. Determine whether AMOTL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2249
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of ZNF789 is measured. Does this perturbation cause a significant change in ZNF789 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of ZNF789 is measured. Does this perturbation cause a significant change in ZNF789 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3220
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of CDK13. Does this perturbation cause a significant change in CDK13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of CDK13. Does this perturbation cause a significant change in CDK13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2764
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in ANKRD10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in ANKRD10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4355
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and FGF11 expression is observed. Does this perturbation lead to a significant difference in FGF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and FGF11 expression is observed. Does this perturbation lead to a significant difference in FGF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4173
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of C9orf64. Does perturbing DDOST lead to a significant change in C9orf64 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of C9orf64. Does perturbing DDOST lead to a significant change in C9orf64 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3871
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ZFP36L2. Does this perturbation cause a significant change in ZFP36L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ZFP36L2. Does this perturbation cause a significant change in ZFP36L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3454
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in GALNT7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in GALNT7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4385
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of ZNF292. Does perturbing SRP68 lead to a significant change in ZNF292 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of ZNF292. Does perturbing SRP68 lead to a significant change in ZNF292 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3561
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and EXO1 expression is observed. Does this perturbation lead to a significant difference in EXO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and EXO1 expression is observed. Does this perturbation lead to a significant difference in EXO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2833
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of ATP6AP2. Does perturbing ATP5B lead to a significant change in ATP6AP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of ATP6AP2. Does perturbing ATP5B lead to a significant change in ATP6AP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1621
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and APOBEC3D expression is quantified. Does this perturbation result in a significant change in APOBEC3D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and APOBEC3D expression is quantified. Does this perturbation result in a significant change in APOBEC3D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3572
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of RHCE. Does perturbing SCYL1 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of RHCE. Does perturbing SCYL1 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3501
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and PRRC2B expression is observed. Does this perturbation lead to a significant difference in PRRC2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and PRRC2B expression is observed. Does this perturbation lead to a significant difference in PRRC2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":903
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP6 is measured. Determine whether ARHGAP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP6 is measured. Determine whether ARHGAP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3426
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in PTBP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in PTBP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":665
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and RP11-90P5.2 expression is measured. Determine whether RP11-90P5.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and RP11-90P5.2 expression is measured. Determine whether RP11-90P5.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":409
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and BRWD3 expression is observed. Does this perturbation lead to a significant difference in BRWD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and BRWD3 expression is observed. Does this perturbation lead to a significant difference in BRWD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":733
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in AC008074.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in AC008074.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1905
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and KANSL1L expression is measured. Determine whether KANSL1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and KANSL1L expression is measured. Determine whether KANSL1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":649
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and PCF11 expression is measured. Determine whether PCF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and PCF11 expression is measured. Determine whether PCF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":549
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and ZP3 expression is observed. Does this perturbation lead to a significant difference in ZP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and ZP3 expression is observed. Does this perturbation lead to a significant difference in ZP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2543
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of WDR3. Does this perturbation cause a significant change in WDR3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of WDR3. Does this perturbation cause a significant change in WDR3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4564
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of RP11-95O2.5. Does this perturbation cause a significant change in RP11-95O2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of RP11-95O2.5. Does this perturbation cause a significant change in RP11-95O2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4474
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of EP400. Does this perturbation cause a significant change in EP400 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of EP400. Does this perturbation cause a significant change in EP400 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3664
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of BIRC5. Does this perturbation cause a significant change in BIRC5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of BIRC5. Does this perturbation cause a significant change in BIRC5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4504
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and SERPINF2 expression is observed. Does this perturbation lead to a significant difference in SERPINF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and SERPINF2 expression is observed. Does this perturbation lead to a significant difference in SERPINF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3953
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor GOT1 expression. Decide whether this perturbation leads to a significant alteration in GOT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor GOT1 expression. Decide whether this perturbation leads to a significant alteration in GOT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1118
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and QSER1 expression is quantified. Does this perturbation result in a significant change in QSER1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and QSER1 expression is quantified. Does this perturbation result in a significant change in QSER1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4682
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and AC096559.1 expression is quantified. Does this perturbation result in a significant change in AC096559.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and AC096559.1 expression is quantified. Does this perturbation result in a significant change in AC096559.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1872
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of THBS1. Does this perturbation cause a significant change in THBS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of THBS1. Does this perturbation cause a significant change in THBS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5014
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor SNRNP25 expression. Decide whether this perturbation leads to a significant alteration in SNRNP25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor SNRNP25 expression. Decide whether this perturbation leads to a significant alteration in SNRNP25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2158
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and CTSF expression is measured. Determine whether CTSF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and CTSF expression is measured. Determine whether CTSF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":159
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor C12orf23 expression. Decide whether this perturbation leads to a significant alteration in C12orf23 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor C12orf23 expression. Decide whether this perturbation leads to a significant alteration in C12orf23 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1768
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in ZNF292 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in ZNF292 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3565
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of ATP11B is measured. Determine whether ATP11B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of ATP11B is measured. Determine whether ATP11B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":296
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of AFF1 is measured. Determine whether AFF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of AFF1 is measured. Determine whether AFF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2916
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in PTPN11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in PTPN11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":505
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and DDIT4 expression is measured. Determine whether DDIT4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and DDIT4 expression is measured. Determine whether DDIT4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1829
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of PPP4R2 is measured. Determine whether PPP4R2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of PPP4R2 is measured. Determine whether PPP4R2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2376
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of BACH2. Does perturbing KCTD16 lead to a significant change in BACH2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of BACH2. Does perturbing KCTD16 lead to a significant change in BACH2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3471
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of PTAR1 is measured. Determine whether PTAR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of PTAR1 is measured. Determine whether PTAR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2106
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of RUNX1. Does perturbing CREB1 lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of RUNX1. Does perturbing CREB1 lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of LINC00938 is measured. Does this perturbation cause a significant change in LINC00938 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of LINC00938 is measured. Does this perturbation cause a significant change in LINC00938 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4100
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and RP13-216E22.4 expression is quantified. Does this perturbation result in a significant change in RP13-216E22.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and RP13-216E22.4 expression is quantified. Does this perturbation result in a significant change in RP13-216E22.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2432
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor RP11-81A22.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-81A22.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor RP11-81A22.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-81A22.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1618
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor WARS expression. Decide whether this perturbation leads to a significant alteration in WARS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor WARS expression. Decide whether this perturbation leads to a significant alteration in WARS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4888
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and PPP1R16B expression is quantified. Does this perturbation result in a significant change in PPP1R16B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and PPP1R16B expression is quantified. Does this perturbation result in a significant change in PPP1R16B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":592
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of EXOC3L2 is measured. Determine whether EXOC3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of EXOC3L2 is measured. Determine whether EXOC3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3356
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of RP11-499F3.2 is measured. Does this perturbation cause a significant change in RP11-499F3.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of RP11-499F3.2 is measured. Does this perturbation cause a significant change in RP11-499F3.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2880
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and ASPM expression is measured. Determine whether ASPM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and ASPM expression is measured. Determine whether ASPM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2669
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in UBE3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in UBE3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1225
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in MBNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in MBNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4815
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor RP11-499F3.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-499F3.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor RP11-499F3.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-499F3.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2888
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of ABI2. Does this perturbation cause a significant change in ABI2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of ABI2. Does this perturbation cause a significant change in ABI2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2024
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and ZNF292 expression is measured. Determine whether ZNF292 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and ZNF292 expression is measured. Determine whether ZNF292 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3569
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and GLG1 expression is measured. Determine whether GLG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and GLG1 expression is measured. Determine whether GLG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1949
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in TOB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in TOB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":985
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of SETD5-AS1 is measured. Does this perturbation cause a significant change in SETD5-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of SETD5-AS1 is measured. Does this perturbation cause a significant change in SETD5-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1180
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RP11-65L19.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RP11-65L19.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and UFD1L expression is measured. Determine whether UFD1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and UFD1L expression is measured. Determine whether UFD1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2509
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and UHMK1 expression is measured. Determine whether UHMK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and UHMK1 expression is measured. Determine whether UHMK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4989
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2125
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and CCRL2 expression is measured. Determine whether CCRL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and CCRL2 expression is measured. Determine whether CCRL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3559
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of IL18R1 is measured. Determine whether IL18R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of IL18R1 is measured. Determine whether IL18R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":356
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2304
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in NBEAL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in NBEAL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of GSN is measured. Does this perturbation cause a significant change in GSN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of GSN is measured. Does this perturbation cause a significant change in GSN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3200
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and TGOLN2 expression is observed. Does this perturbation lead to a significant difference in TGOLN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and TGOLN2 expression is observed. Does this perturbation lead to a significant difference in TGOLN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5093
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and VIMP expression is quantified. Does this perturbation result in a significant change in VIMP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and VIMP expression is quantified. Does this perturbation result in a significant change in VIMP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4582
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and TTC32 expression is quantified. Does this perturbation result in a significant change in TTC32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and TTC32 expression is quantified. Does this perturbation result in a significant change in TTC32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3212
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and RP11-360L9.8 expression is quantified. Does this perturbation result in a significant change in RP11-360L9.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and RP11-360L9.8 expression is quantified. Does this perturbation result in a significant change in RP11-360L9.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2792
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of ZNF280B is measured. Does this perturbation cause a significant change in ZNF280B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of ZNF280B is measured. Does this perturbation cause a significant change in ZNF280B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1100
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of CPQ is measured. Does this perturbation cause a significant change in CPQ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of CPQ is measured. Does this perturbation cause a significant change in CPQ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2960
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and LINC00657 expression is observed. Does this perturbation lead to a significant difference in LINC00657 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and LINC00657 expression is observed. Does this perturbation lead to a significant difference in LINC00657 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":253
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and PAK1IP1 expression is measured. Determine whether PAK1IP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and PAK1IP1 expression is measured. Determine whether PAK1IP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4259
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of LAMP2. Does this perturbation cause a significant change in LAMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of LAMP2. Does this perturbation cause a significant change in LAMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2774
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in AC015987.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in AC015987.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2255
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of HIST1H1E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of HIST1H1E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1027
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of PCF11. Does this perturbation cause a significant change in PCF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of PCF11. Does this perturbation cause a significant change in PCF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":544
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of AMOTL1. Does perturbing NEDD8 lead to a significant change in AMOTL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of AMOTL1. Does perturbing NEDD8 lead to a significant change in AMOTL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2241
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of SPCS2 is measured. Determine whether SPCS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of SPCS2 is measured. Determine whether SPCS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":696
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor USP37 expression. Decide whether this perturbation leads to a significant alteration in USP37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor USP37 expression. Decide whether this perturbation leads to a significant alteration in USP37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1738
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and CASP4 expression is quantified. Does this perturbation result in a significant change in CASP4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and CASP4 expression is quantified. Does this perturbation result in a significant change in CASP4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of RP11-24F11.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of RP11-24F11.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1497
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and AC007038.7 expression is quantified. Does this perturbation result in a significant change in AC007038.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and AC007038.7 expression is quantified. Does this perturbation result in a significant change in AC007038.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2922
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor ZNF292 expression. Decide whether this perturbation leads to a significant alteration in ZNF292 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor ZNF292 expression. Decide whether this perturbation leads to a significant alteration in ZNF292 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1508
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in AC007038.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in AC007038.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2925
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and EP400 expression is quantified. Does this perturbation result in a significant change in EP400 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and EP400 expression is quantified. Does this perturbation result in a significant change in EP400 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3662
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and PAXBP1 expression is observed. Does this perturbation lead to a significant difference in PAXBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and PAXBP1 expression is observed. Does this perturbation lead to a significant difference in PAXBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4743
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and FOXO6 expression is quantified. Does this perturbation result in a significant change in FOXO6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and FOXO6 expression is quantified. Does this perturbation result in a significant change in FOXO6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4122
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and WHSC1 expression is measured. Determine whether WHSC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and WHSC1 expression is measured. Determine whether WHSC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1489
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of UQCRB is measured. Determine whether UQCRB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of UQCRB is measured. Determine whether UQCRB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":706
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of ZEB1. Does this perturbation cause a significant change in ZEB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of ZEB1. Does this perturbation cause a significant change in ZEB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1384
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and FAM212A expression is observed. Does this perturbation lead to a significant difference in FAM212A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and FAM212A expression is observed. Does this perturbation lead to a significant difference in FAM212A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2233
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in KANSL1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in KANSL1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":645
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and PPP1R16B expression is measured. Determine whether PPP1R16B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and PPP1R16B expression is measured. Determine whether PPP1R16B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4489
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of RP11-445H22.3 is measured. Does this perturbation cause a significant change in RP11-445H22.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of RP11-445H22.3 is measured. Does this perturbation cause a significant change in RP11-445H22.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3810
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of STARD9 is measured. Determine whether STARD9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of STARD9 is measured. Determine whether STARD9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4606
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of P4HA2. Does this perturbation cause a significant change in P4HA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of P4HA2. Does this perturbation cause a significant change in P4HA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2404
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of TSNAXIP1. Does this perturbation cause a significant change in TSNAXIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of TSNAXIP1. Does this perturbation cause a significant change in TSNAXIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":754
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and HPCAL1 expression is quantified. Does this perturbation result in a significant change in HPCAL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and HPCAL1 expression is quantified. Does this perturbation result in a significant change in HPCAL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2972
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of CHD3. Does this perturbation cause a significant change in CHD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of CHD3. Does this perturbation cause a significant change in CHD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4904
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and PDE3B expression is quantified. Does this perturbation result in a significant change in PDE3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and PDE3B expression is quantified. Does this perturbation result in a significant change in PDE3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4782
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of ZFHX3. Does perturbing SOCS1 lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of ZFHX3. Does perturbing SOCS1 lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1131
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of KLF6. Does this perturbation cause a significant change in KLF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of KLF6. Does this perturbation cause a significant change in KLF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2294
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor S100A13 expression. Decide whether this perturbation leads to a significant alteration in S100A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor S100A13 expression. Decide whether this perturbation leads to a significant alteration in S100A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2788
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and WARS expression is quantified. Does this perturbation result in a significant change in WARS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and WARS expression is quantified. Does this perturbation result in a significant change in WARS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4882
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and SHOX2 expression is observed. Does this perturbation lead to a significant difference in SHOX2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and SHOX2 expression is observed. Does this perturbation lead to a significant difference in SHOX2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":993
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of RP11-2H8.2 is measured. Does this perturbation cause a significant change in RP11-2H8.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of RP11-2H8.2 is measured. Does this perturbation cause a significant change in RP11-2H8.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3590
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and SPINK5 expression is quantified. Does this perturbation result in a significant change in SPINK5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and SPINK5 expression is quantified. Does this perturbation result in a significant change in SPINK5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":412
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ARHGAP6. Does this perturbation cause a significant change in ARHGAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ARHGAP6. Does this perturbation cause a significant change in ARHGAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3424
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor TNFRSF10B expression. Decide whether this perturbation leads to a significant alteration in TNFRSF10B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor TNFRSF10B expression. Decide whether this perturbation leads to a significant alteration in TNFRSF10B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3868
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and ATP6AP2 expression is observed. Does this perturbation lead to a significant difference in ATP6AP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and ATP6AP2 expression is observed. Does this perturbation lead to a significant difference in ATP6AP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1623
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of SMCO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of SMCO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4497
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of AMOTL1 is measured. Determine whether AMOTL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of AMOTL1 is measured. Determine whether AMOTL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2246
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in SERPINH1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in SERPINH1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1645
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor ERP29 expression. Decide whether this perturbation leads to a significant alteration in ERP29 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor ERP29 expression. Decide whether this perturbation leads to a significant alteration in ERP29 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5078
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of NOSTRIN. Does this perturbation cause a significant change in NOSTRIN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of NOSTRIN. Does this perturbation cause a significant change in NOSTRIN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4324
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and CDKN2C expression is observed. Does this perturbation lead to a significant difference in CDKN2C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and CDKN2C expression is observed. Does this perturbation lead to a significant difference in CDKN2C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2813
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of IFT27 is measured. Determine whether IFT27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of IFT27 is measured. Determine whether IFT27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4226
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in FGF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in FGF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4175
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of IDS. Does perturbing AARS lead to a significant change in IDS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of IDS. Does perturbing AARS lead to a significant change in IDS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4271
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in NOSTRIN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in NOSTRIN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4325
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor GALNT7 expression. Decide whether this perturbation leads to a significant alteration in GALNT7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor GALNT7 expression. Decide whether this perturbation leads to a significant alteration in GALNT7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4388
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and KCNJ13 expression is observed. Does this perturbation lead to a significant difference in KCNJ13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and KCNJ13 expression is observed. Does this perturbation lead to a significant difference in KCNJ13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3653
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and RTN2 expression is measured. Determine whether RTN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and RTN2 expression is measured. Determine whether RTN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2069
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of LTN1 is measured. Does this perturbation cause a significant change in LTN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of LTN1 is measured. Does this perturbation cause a significant change in LTN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3780
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and C19orf59 expression is measured. Determine whether C19orf59 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and C19orf59 expression is measured. Determine whether C19orf59 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2349
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of DUT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of DUT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":277
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of IL8. Does this perturbation cause a significant change in IL8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of IL8. Does this perturbation cause a significant change in IL8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1254
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of KCTD19 is measured. Does this perturbation cause a significant change in KCTD19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of KCTD19 is measured. Does this perturbation cause a significant change in KCTD19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2680
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and PCF11 expression is quantified. Does this perturbation result in a significant change in PCF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and PCF11 expression is quantified. Does this perturbation result in a significant change in PCF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":542
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in C12orf44 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in C12orf44 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1535
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and RP11-430H10.1 expression is measured. Determine whether RP11-430H10.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and RP11-430H10.1 expression is measured. Determine whether RP11-430H10.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5029
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of JARID2 is measured. Does this perturbation cause a significant change in JARID2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of JARID2 is measured. Does this perturbation cause a significant change in JARID2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1210
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of DDIT4 is measured. Determine whether DDIT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of DDIT4 is measured. Determine whether DDIT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1826
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4758
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of RASGRP2 is measured. Determine whether RASGRP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of RASGRP2 is measured. Determine whether RASGRP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4266
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of HOTAIRM1. Does this perturbation cause a significant change in HOTAIRM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of HOTAIRM1. Does this perturbation cause a significant change in HOTAIRM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1264
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of LTBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of LTBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1807
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of SMCO1 is measured. Does this perturbation cause a significant change in SMCO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of SMCO1 is measured. Does this perturbation cause a significant change in SMCO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4490
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of COPB1 is measured. Determine whether COPB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of COPB1 is measured. Determine whether COPB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":806
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of APOL4 is measured. Determine whether APOL4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of APOL4 is measured. Determine whether APOL4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":896
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of IL32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of IL32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":567
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and TOPBP1 expression is observed. Does this perturbation lead to a significant difference in TOPBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and TOPBP1 expression is observed. Does this perturbation lead to a significant difference in TOPBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2893
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of AC104532.4 is measured. Determine whether AC104532.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of AC104532.4 is measured. Determine whether AC104532.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2986
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of AC104532.4 is measured. Does this perturbation cause a significant change in AC104532.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of AC104532.4 is measured. Does this perturbation cause a significant change in AC104532.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2980
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and HOTAIRM1 expression is quantified. Does this perturbation result in a significant change in HOTAIRM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and HOTAIRM1 expression is quantified. Does this perturbation result in a significant change in HOTAIRM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1262
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor MT2A expression. Decide whether this perturbation leads to a significant alteration in MT2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor MT2A expression. Decide whether this perturbation leads to a significant alteration in MT2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3168
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and SLC26A1 expression is measured. Determine whether SLC26A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and SLC26A1 expression is measured. Determine whether SLC26A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2199
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and ANKRD10 expression is observed. Does this perturbation lead to a significant difference in ANKRD10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and ANKRD10 expression is observed. Does this perturbation lead to a significant difference in ANKRD10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4353
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in ZEB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in ZEB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1385
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of SNHG10 is measured. Does this perturbation cause a significant change in SNHG10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of SNHG10 is measured. Does this perturbation cause a significant change in SNHG10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1880
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and CDT1 expression is quantified. Does this perturbation result in a significant change in CDT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and CDT1 expression is quantified. Does this perturbation result in a significant change in CDT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5122
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of C19orf59 is measured. Does this perturbation cause a significant change in C19orf59 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of C19orf59 is measured. Does this perturbation cause a significant change in C19orf59 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2340
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in WDR3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in WDR3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4565
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of TROAP. Does this perturbation cause a significant change in TROAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of TROAP. Does this perturbation cause a significant change in TROAP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3084
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of TNFRSF10B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of TNFRSF10B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2287
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor C3AR1 expression. Decide whether this perturbation leads to a significant alteration in C3AR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor C3AR1 expression. Decide whether this perturbation leads to a significant alteration in C3AR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3408
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and CDT1 expression is measured. Determine whether CDT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and CDT1 expression is measured. Determine whether CDT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5129
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of ZP3. Does perturbing FARSB lead to a significant change in ZP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of ZP3. Does perturbing FARSB lead to a significant change in ZP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2541
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1957
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of TMOD3 is measured. Determine whether TMOD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of TMOD3 is measured. Determine whether TMOD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1516
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and LTN1 expression is measured. Determine whether LTN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and LTN1 expression is measured. Determine whether LTN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3789
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of CD46. Does this perturbation cause a significant change in CD46 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of CD46. Does this perturbation cause a significant change in CD46 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4214
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of S100A13. Does this perturbation cause a significant change in S100A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of S100A13. Does this perturbation cause a significant change in S100A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2784
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of RP11-254F7.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of RP11-254F7.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2397
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of KCNJ13 is measured. Determine whether KCNJ13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of KCNJ13 is measured. Determine whether KCNJ13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3656
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and AP000688.8 expression is observed. Does this perturbation lead to a significant difference in AP000688.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and AP000688.8 expression is observed. Does this perturbation lead to a significant difference in AP000688.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3333
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of RP11-360L9.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of RP11-360L9.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4297
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in PCK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in PCK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3015
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and SNHG10 expression is observed. Does this perturbation lead to a significant difference in SNHG10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and SNHG10 expression is observed. Does this perturbation lead to a significant difference in SNHG10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1313
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and HMGCS1 expression is observed. Does this perturbation lead to a significant difference in HMGCS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and HMGCS1 expression is observed. Does this perturbation lead to a significant difference in HMGCS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":373
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in PIK3IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in PIK3IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2865
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of TOPBP1 is measured. Determine whether TOPBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of TOPBP1 is measured. Determine whether TOPBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2896
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and EPB42 expression is measured. Determine whether EPB42 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and EPB42 expression is measured. Determine whether EPB42 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1719
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of KLF3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of KLF3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1987
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in RGS20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in RGS20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3125
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in RP11-334C17.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in RP11-334C17.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1005
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of F2RL2. Does this perturbation cause a significant change in F2RL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of F2RL2. Does this perturbation cause a significant change in F2RL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2334
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor RP11-95O2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-95O2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor RP11-95O2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-95O2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4478
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of RP11-254F7.4 is measured. Does this perturbation cause a significant change in RP11-254F7.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of RP11-254F7.4 is measured. Does this perturbation cause a significant change in RP11-254F7.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2390
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and DOCK11 expression is observed. Does this perturbation lead to a significant difference in DOCK11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and DOCK11 expression is observed. Does this perturbation lead to a significant difference in DOCK11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":363
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and ACRV1 expression is measured. Determine whether ACRV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and ACRV1 expression is measured. Determine whether ACRV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3899
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of NCKAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of NCKAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":447
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of LTN1. Does perturbing HYOU1 lead to a significant change in LTN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of LTN1. Does perturbing HYOU1 lead to a significant change in LTN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3781
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor HLA-E expression. Decide whether this perturbation leads to a significant alteration in HLA-E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor HLA-E expression. Decide whether this perturbation leads to a significant alteration in HLA-E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3268
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in HLA-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in HLA-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":765
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ACE expression is quantified. Does this perturbation result in a significant change in ACE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ACE expression is quantified. Does this perturbation result in a significant change in ACE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2572
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor RP11-360L9.8 expression. Decide whether this perturbation leads to a significant alteration in RP11-360L9.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor RP11-360L9.8 expression. Decide whether this perturbation leads to a significant alteration in RP11-360L9.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2798
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and UHMK1 expression is quantified. Does this perturbation result in a significant change in UHMK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and UHMK1 expression is quantified. Does this perturbation result in a significant change in UHMK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4982
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of AP000688.8. Does perturbing PSMD4 lead to a significant change in AP000688.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of AP000688.8. Does perturbing PSMD4 lead to a significant change in AP000688.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3331
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of TMEM87B is measured. Does this perturbation cause a significant change in TMEM87B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of TMEM87B is measured. Does this perturbation cause a significant change in TMEM87B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":820
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in ANKLE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in ANKLE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2315
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of KCTD1. Does perturbing STT3A lead to a significant change in KCTD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of KCTD1. Does perturbing STT3A lead to a significant change in KCTD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1371
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of SHOX2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of SHOX2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":997
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of SDF4 is measured. Does this perturbation cause a significant change in SDF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of SDF4 is measured. Does this perturbation cause a significant change in SDF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1770
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in SLFNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in SLFNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":455
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in ZNF280B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in ZNF280B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1285
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and H1FX expression is observed. Does this perturbation lead to a significant difference in H1FX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and H1FX expression is observed. Does this perturbation lead to a significant difference in H1FX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4673
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of ZNF678. Does this perturbation cause a significant change in ZNF678 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of ZNF678. Does this perturbation cause a significant change in ZNF678 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1364
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and CPQ expression is observed. Does this perturbation lead to a significant difference in CPQ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and CPQ expression is observed. Does this perturbation lead to a significant difference in CPQ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2963
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of THBS1 is measured. Does this perturbation cause a significant change in THBS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of THBS1 is measured. Does this perturbation cause a significant change in THBS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5010
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and SMCO1 expression is quantified. Does this perturbation result in a significant change in SMCO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and SMCO1 expression is quantified. Does this perturbation result in a significant change in SMCO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4492
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and BOLA3 expression is observed. Does this perturbation lead to a significant difference in BOLA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and BOLA3 expression is observed. Does this perturbation lead to a significant difference in BOLA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4633
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of ANKRD10 is measured. Determine whether ANKRD10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of ANKRD10 is measured. Determine whether ANKRD10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4356
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of PAXBP1 is measured. Determine whether PAXBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of PAXBP1 is measured. Determine whether PAXBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4746
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of DNASE2. Does perturbing ATP5B lead to a significant change in DNASE2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of DNASE2. Does perturbing ATP5B lead to a significant change in DNASE2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1631
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of PDE3B. Does this perturbation cause a significant change in PDE3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of PDE3B. Does this perturbation cause a significant change in PDE3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4784
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1695
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of RILPL2 is measured. Does this perturbation cause a significant change in RILPL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of RILPL2 is measured. Does this perturbation cause a significant change in RILPL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2800
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and RCBTB2 expression is observed. Does this perturbation lead to a significant difference in RCBTB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and RCBTB2 expression is observed. Does this perturbation lead to a significant difference in RCBTB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1333
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and APOL4 expression is measured. Determine whether APOL4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and APOL4 expression is measured. Determine whether APOL4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":899
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of RP1-274L7.1. Does perturbing CCND3 lead to a significant change in RP1-274L7.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of RP1-274L7.1. Does perturbing CCND3 lead to a significant change in RP1-274L7.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4071
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and UQCRB expression is observed. Does this perturbation lead to a significant difference in UQCRB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and UQCRB expression is observed. Does this perturbation lead to a significant difference in UQCRB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":703
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of NOXA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of NOXA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1417
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ZXDA is measured. Does this perturbation cause a significant change in ZXDA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ZXDA is measured. Does this perturbation cause a significant change in ZXDA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3930
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in UHMK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in UHMK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4985
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of KHDC1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of KHDC1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1067
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor OXLD1 expression. Decide whether this perturbation leads to a significant alteration in OXLD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor OXLD1 expression. Decide whether this perturbation leads to a significant alteration in OXLD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2858
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and TAGLN expression is measured. Determine whether TAGLN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and TAGLN expression is measured. Determine whether TAGLN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1359
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of NTRK1. Does this perturbation cause a significant change in NTRK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of NTRK1. Does this perturbation cause a significant change in NTRK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4034
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and AFF1 expression is measured. Determine whether AFF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and AFF1 expression is measured. Determine whether AFF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2919
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and GPRC5C expression is measured. Determine whether GPRC5C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and GPRC5C expression is measured. Determine whether GPRC5C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2229
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor EXO1 expression. Decide whether this perturbation leads to a significant alteration in EXO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor EXO1 expression. Decide whether this perturbation leads to a significant alteration in EXO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2838
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of F2RL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of F2RL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2337
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and TMEM87B expression is observed. Does this perturbation lead to a significant difference in TMEM87B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and TMEM87B expression is observed. Does this perturbation lead to a significant difference in TMEM87B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":823
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of TMOD3. Does perturbing SEL1L lead to a significant change in TMOD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of TMOD3. Does perturbing SEL1L lead to a significant change in TMOD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1511
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and PTGS1 expression is quantified. Does this perturbation result in a significant change in PTGS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and PTGS1 expression is quantified. Does this perturbation result in a significant change in PTGS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3482
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of SETD5-AS1. Does this perturbation cause a significant change in SETD5-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of SETD5-AS1. Does this perturbation cause a significant change in SETD5-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1184
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of KIAA1432. Does perturbing PTDSS1 lead to a significant change in KIAA1432 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of KIAA1432. Does perturbing PTDSS1 lead to a significant change in KIAA1432 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3751
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of ANKRD11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of ANKRD11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4697
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of MS4A6E. Does this perturbation cause a significant change in MS4A6E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of MS4A6E. Does this perturbation cause a significant change in MS4A6E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":344
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of GCKR. Does this perturbation cause a significant change in GCKR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of GCKR. Does this perturbation cause a significant change in GCKR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4304
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of P4HA2 is measured. Does this perturbation cause a significant change in P4HA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of P4HA2 is measured. Does this perturbation cause a significant change in P4HA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor LINC00657 expression. Decide whether this perturbation leads to a significant alteration in LINC00657 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor LINC00657 expression. Decide whether this perturbation leads to a significant alteration in LINC00657 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":258
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1953
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of AC012594.1. Does this perturbation cause a significant change in AC012594.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of AC012594.1. Does this perturbation cause a significant change in AC012594.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1674
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and IDH3A expression is quantified. Does this perturbation result in a significant change in IDH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and IDH3A expression is quantified. Does this perturbation result in a significant change in IDH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2642
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and OBSCN expression is observed. Does this perturbation lead to a significant difference in OBSCN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and OBSCN expression is observed. Does this perturbation lead to a significant difference in OBSCN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3823
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of DOCK11 is measured. Does this perturbation cause a significant change in DOCK11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of DOCK11 is measured. Does this perturbation cause a significant change in DOCK11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":360
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of SNHG10. Does this perturbation cause a significant change in SNHG10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of SNHG10. Does this perturbation cause a significant change in SNHG10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1884
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and SLC27A2 expression is quantified. Does this perturbation result in a significant change in SLC27A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and SLC27A2 expression is quantified. Does this perturbation result in a significant change in SLC27A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3682
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":319
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and EP300 expression is quantified. Does this perturbation result in a significant change in EP300 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and EP300 expression is quantified. Does this perturbation result in a significant change in EP300 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1682
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of SOBP is measured. Does this perturbation cause a significant change in SOBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of SOBP is measured. Does this perturbation cause a significant change in SOBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3630
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and MYH7B expression is observed. Does this perturbation lead to a significant difference in MYH7B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and MYH7B expression is observed. Does this perturbation lead to a significant difference in MYH7B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":583
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor SERPING1 expression. Decide whether this perturbation leads to a significant alteration in SERPING1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor SERPING1 expression. Decide whether this perturbation leads to a significant alteration in SERPING1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3248
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of SMCO1. Does perturbing PPWD1 lead to a significant change in SMCO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of SMCO1. Does perturbing PPWD1 lead to a significant change in SMCO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4491
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in SPINK5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in SPINK5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":415
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1956
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of CDK13 is measured. Does this perturbation cause a significant change in CDK13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of CDK13 is measured. Does this perturbation cause a significant change in CDK13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2760
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and GS1-166A23.1 expression is measured. Determine whether GS1-166A23.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and GS1-166A23.1 expression is measured. Determine whether GS1-166A23.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3299
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of IL13RA1. Does perturbing HSPA9 lead to a significant change in IL13RA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of IL13RA1. Does perturbing HSPA9 lead to a significant change in IL13RA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2351
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of CELF6 is measured. Does this perturbation cause a significant change in CELF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of CELF6 is measured. Does this perturbation cause a significant change in CELF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5030
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and KLF6 expression is measured. Determine whether KLF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and KLF6 expression is measured. Determine whether KLF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2299
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in ATP5EP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in ATP5EP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2955
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of TAGLN is measured. Determine whether TAGLN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of TAGLN is measured. Determine whether TAGLN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1356
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of TKTL1. Does perturbing BHLHE40 lead to a significant change in TKTL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of TKTL1. Does perturbing BHLHE40 lead to a significant change in TKTL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":171
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and AP000688.8 expression is measured. Determine whether AP000688.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and AP000688.8 expression is measured. Determine whether AP000688.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3339
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in RP11-212I21.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in RP11-212I21.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2035
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of RNF8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of RNF8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3187
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in CLDN11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in CLDN11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2615
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and USP34 expression is measured. Determine whether USP34 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and USP34 expression is measured. Determine whether USP34 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4369
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1135
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in OR2T6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in OR2T6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1845
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of RP1-274L7.1 is measured. Does this perturbation cause a significant change in RP1-274L7.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of RP1-274L7.1 is measured. Does this perturbation cause a significant change in RP1-274L7.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4070
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor CDT1 expression. Decide whether this perturbation leads to a significant alteration in CDT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor CDT1 expression. Decide whether this perturbation leads to a significant alteration in CDT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5128
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in STK17B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in STK17B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4855
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and ATP2A3 expression is measured. Determine whether ATP2A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and ATP2A3 expression is measured. Determine whether ATP2A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1839
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and GLG1 expression is quantified. Does this perturbation result in a significant change in GLG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and GLG1 expression is quantified. Does this perturbation result in a significant change in GLG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1942
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor PAK1IP1 expression. Decide whether this perturbation leads to a significant alteration in PAK1IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor PAK1IP1 expression. Decide whether this perturbation leads to a significant alteration in PAK1IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4258
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and AC104532.4 expression is measured. Determine whether AC104532.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and AC104532.4 expression is measured. Determine whether AC104532.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2989
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and NAV2 expression is measured. Determine whether NAV2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and NAV2 expression is measured. Determine whether NAV2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4869
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of RP11-838N2.4. Does perturbing EIF2B2 lead to a significant change in RP11-838N2.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of RP11-838N2.4. Does perturbing EIF2B2 lead to a significant change in RP11-838N2.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3031
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of SNHG7. Does this perturbation cause a significant change in SNHG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of SNHG7. Does this perturbation cause a significant change in SNHG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4044
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of RILPL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of RILPL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2807
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of SEC23IP is measured. Determine whether SEC23IP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of SEC23IP is measured. Determine whether SEC23IP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3976
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1136
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of CD83 is measured. Does this perturbation cause a significant change in CD83 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of CD83 is measured. Does this perturbation cause a significant change in CD83 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2690
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and IDS expression is observed. Does this perturbation lead to a significant difference in IDS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and IDS expression is observed. Does this perturbation lead to a significant difference in IDS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4273
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor CTD-2587M2.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2587M2.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor CTD-2587M2.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2587M2.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1918
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of SERPINH1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of SERPINH1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1647
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of NRIP1. Does this perturbation cause a significant change in NRIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of NRIP1. Does this perturbation cause a significant change in NRIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":124
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in BAMBI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in BAMBI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1175
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of RP11-789C1.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of RP11-789C1.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":947
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of CENPC. Does this perturbation cause a significant change in CENPC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of CENPC. Does this perturbation cause a significant change in CENPC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4454
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in DNMBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in DNMBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4015
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and ZNF280B expression is quantified. Does this perturbation result in a significant change in ZNF280B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and ZNF280B expression is quantified. Does this perturbation result in a significant change in ZNF280B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1102
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of LINC00657 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of LINC00657 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":257
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of WHSC1. Does this perturbation cause a significant change in WHSC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of WHSC1. Does this perturbation cause a significant change in WHSC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1484
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of HM13. Does this perturbation cause a significant change in HM13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of HM13. Does this perturbation cause a significant change in HM13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4514
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and AC079466.1 expression is quantified. Does this perturbation result in a significant change in AC079466.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and AC079466.1 expression is quantified. Does this perturbation result in a significant change in AC079466.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1442
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and RP11-471M2.3 expression is observed. Does this perturbation lead to a significant difference in RP11-471M2.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and RP11-471M2.3 expression is observed. Does this perturbation lead to a significant difference in RP11-471M2.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2593
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of VPS41. Does this perturbation cause a significant change in VPS41 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of VPS41. Does this perturbation cause a significant change in VPS41 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":634
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and RPL39 expression is quantified. Does this perturbation result in a significant change in RPL39 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and RPL39 expression is quantified. Does this perturbation result in a significant change in RPL39 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1742
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor EPB42 expression. Decide whether this perturbation leads to a significant alteration in EPB42 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor EPB42 expression. Decide whether this perturbation leads to a significant alteration in EPB42 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1718
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of NAV2. Does this perturbation cause a significant change in NAV2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of NAV2. Does this perturbation cause a significant change in NAV2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4864
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and CCRL2 expression is quantified. Does this perturbation result in a significant change in CCRL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and CCRL2 expression is quantified. Does this perturbation result in a significant change in CCRL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3552
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of KHDC1L is measured. Does this perturbation cause a significant change in KHDC1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of KHDC1L is measured. Does this perturbation cause a significant change in KHDC1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1060
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and TIPARP expression is measured. Determine whether TIPARP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and TIPARP expression is measured. Determine whether TIPARP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3619
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of RP3-465N24.6 is measured. Does this perturbation cause a significant change in RP3-465N24.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of RP3-465N24.6 is measured. Does this perturbation cause a significant change in RP3-465N24.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3580
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of SLFNL1. Does perturbing SRPR lead to a significant change in SLFNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of SLFNL1. Does perturbing SRPR lead to a significant change in SLFNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":451
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of RPL39 is measured. Does this perturbation cause a significant change in RPL39 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of RPL39 is measured. Does this perturbation cause a significant change in RPL39 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1740
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of HIST1H2AC. Does perturbing EIF2B2 lead to a significant change in HIST1H2AC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of HIST1H2AC. Does perturbing EIF2B2 lead to a significant change in HIST1H2AC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3021
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in HIST1H2AM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in HIST1H2AM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2425
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and ZNF341 expression is observed. Does this perturbation lead to a significant difference in ZNF341 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and ZNF341 expression is observed. Does this perturbation lead to a significant difference in ZNF341 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3773
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and ATXN7L3B expression is observed. Does this perturbation lead to a significant difference in ATXN7L3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and ATXN7L3B expression is observed. Does this perturbation lead to a significant difference in ATXN7L3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4933
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and ANKRD33 expression is quantified. Does this perturbation result in a significant change in ANKRD33 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and ANKRD33 expression is quantified. Does this perturbation result in a significant change in ANKRD33 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4182
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of ZNF789 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of ZNF789 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3227
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and CTD-2267D19.3 expression is quantified. Does this perturbation result in a significant change in CTD-2267D19.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and CTD-2267D19.3 expression is quantified. Does this perturbation result in a significant change in CTD-2267D19.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1542
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of C19orf59. Does perturbing HSPA9 lead to a significant change in C19orf59 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of C19orf59. Does perturbing HSPA9 lead to a significant change in C19orf59 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2341
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of OBSCN is measured. Does this perturbation cause a significant change in OBSCN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of OBSCN is measured. Does this perturbation cause a significant change in OBSCN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3820
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of RP11-138C9.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of RP11-138C9.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":837
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of ITGB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of ITGB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1307
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of CTD-2521M24.9. Does this perturbation cause a significant change in CTD-2521M24.9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of CTD-2521M24.9. Does this perturbation cause a significant change in CTD-2521M24.9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2994
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of RP11-360L9.8. Does perturbing AARS lead to a significant change in RP11-360L9.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of RP11-360L9.8. Does perturbing AARS lead to a significant change in RP11-360L9.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4291
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in CDKN2C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in CDKN2C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2815
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of TLN1. Does this perturbation cause a significant change in TLN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of TLN1. Does this perturbation cause a significant change in TLN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1034
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor EP300 expression. Decide whether this perturbation leads to a significant alteration in EP300 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor EP300 expression. Decide whether this perturbation leads to a significant alteration in EP300 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2058
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and LRIF1 expression is measured. Determine whether LRIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and LRIF1 expression is measured. Determine whether LRIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1459
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and IDH3A expression is measured. Determine whether IDH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and IDH3A expression is measured. Determine whether IDH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2649
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor PCF11 expression. Decide whether this perturbation leads to a significant alteration in PCF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor PCF11 expression. Decide whether this perturbation leads to a significant alteration in PCF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5068
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of HIST1H2AC is measured. Determine whether HIST1H2AC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of HIST1H2AC is measured. Determine whether HIST1H2AC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3026
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of SPEN. Does this perturbation cause a significant change in SPEN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of SPEN. Does this perturbation cause a significant change in SPEN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1574
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor C12orf44 expression. Decide whether this perturbation leads to a significant alteration in C12orf44 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor C12orf44 expression. Decide whether this perturbation leads to a significant alteration in C12orf44 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1538
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor ATP6V1B2 expression. Decide whether this perturbation leads to a significant alteration in ATP6V1B2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor ATP6V1B2 expression. Decide whether this perturbation leads to a significant alteration in ATP6V1B2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1608
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of RSL24D1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of RSL24D1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":877
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and RP11-304M2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-304M2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and RP11-304M2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-304M2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4533
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of DOCK8. Does perturbing PDIA6 lead to a significant change in DOCK8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of DOCK8. Does perturbing PDIA6 lead to a significant change in DOCK8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1561
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and PTAR1 expression is observed. Does this perturbation lead to a significant difference in PTAR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and PTAR1 expression is observed. Does this perturbation lead to a significant difference in PTAR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2103
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of RP11-360L9.8. Does this perturbation cause a significant change in RP11-360L9.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of RP11-360L9.8. Does this perturbation cause a significant change in RP11-360L9.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2794
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of LBX1 is measured. Determine whether LBX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of LBX1 is measured. Determine whether LBX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1596
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in BOLA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in BOLA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4635
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and LTB expression is measured. Determine whether LTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and LTB expression is measured. Determine whether LTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":329
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in TUBA1C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in TUBA1C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3395
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and PPM1N expression is observed. Does this perturbation lead to a significant difference in PPM1N expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and PPM1N expression is observed. Does this perturbation lead to a significant difference in PPM1N expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3923
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of HLTF. Does perturbing GBF1 lead to a significant change in HLTF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of HLTF. Does perturbing GBF1 lead to a significant change in HLTF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2481
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and MORC2-AS1 expression is quantified. Does this perturbation result in a significant change in MORC2-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and MORC2-AS1 expression is quantified. Does this perturbation result in a significant change in MORC2-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2552
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of PHF21A. Does this perturbation cause a significant change in PHF21A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of PHF21A. Does this perturbation cause a significant change in PHF21A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3854
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and KLF6 expression is observed. Does this perturbation lead to a significant difference in KLF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and KLF6 expression is observed. Does this perturbation lead to a significant difference in KLF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2293
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of PDRG1. Does perturbing COPB1 lead to a significant change in PDRG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of PDRG1. Does perturbing COPB1 lead to a significant change in PDRG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4151
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of ZNF678. Does perturbing STT3A lead to a significant change in ZNF678 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of ZNF678. Does perturbing STT3A lead to a significant change in ZNF678 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1361
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of SIGLEC6 is measured. Does this perturbation cause a significant change in SIGLEC6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of SIGLEC6 is measured. Does this perturbation cause a significant change in SIGLEC6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3340
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and DNMBP expression is quantified. Does this perturbation result in a significant change in DNMBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and DNMBP expression is quantified. Does this perturbation result in a significant change in DNMBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4012
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in ERP29 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in ERP29 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5075
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of RBM12B-AS1. Does this perturbation cause a significant change in RBM12B-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of RBM12B-AS1. Does this perturbation cause a significant change in RBM12B-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2514
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of UQCRB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of UQCRB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":707
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and FCGRT expression is quantified. Does this perturbation result in a significant change in FCGRT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and FCGRT expression is quantified. Does this perturbation result in a significant change in FCGRT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3532
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor CCRL2 expression. Decide whether this perturbation leads to a significant alteration in CCRL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor CCRL2 expression. Decide whether this perturbation leads to a significant alteration in CCRL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3558
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and IL18R1 expression is observed. Does this perturbation lead to a significant difference in IL18R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and IL18R1 expression is observed. Does this perturbation lead to a significant difference in IL18R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":353
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in SKIL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in SKIL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2945
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of RP11-227G15.8 is measured. Determine whether RP11-227G15.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of RP11-227G15.8 is measured. Determine whether RP11-227G15.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2936
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of APOBEC3D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of APOBEC3D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3577
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and RP11-24F11.2 expression is observed. Does this perturbation lead to a significant difference in RP11-24F11.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and RP11-24F11.2 expression is observed. Does this perturbation lead to a significant difference in RP11-24F11.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1493
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of VIM-AS1. Does perturbing SYVN1 lead to a significant change in VIM-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of VIM-AS1. Does perturbing SYVN1 lead to a significant change in VIM-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1721
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RP11-141B14.1 is measured. Does this perturbation cause a significant change in RP11-141B14.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RP11-141B14.1 is measured. Does this perturbation cause a significant change in RP11-141B14.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in RIMS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in RIMS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":165
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor PBDC1 expression. Decide whether this perturbation leads to a significant alteration in PBDC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor PBDC1 expression. Decide whether this perturbation leads to a significant alteration in PBDC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":608
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor PSMC1 expression. Decide whether this perturbation leads to a significant alteration in PSMC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor PSMC1 expression. Decide whether this perturbation leads to a significant alteration in PSMC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2828
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and EP300 expression is quantified. Does this perturbation result in a significant change in EP300 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and EP300 expression is quantified. Does this perturbation result in a significant change in EP300 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2052
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of RBM12B-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of RBM12B-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2517
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2733
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of ADAMTS10. Does perturbing IARS2 lead to a significant change in ADAMTS10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of ADAMTS10. Does perturbing IARS2 lead to a significant change in ADAMTS10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1071
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in ANKRD11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in ANKRD11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4695
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of MBNL1 is measured. Does this perturbation cause a significant change in MBNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of MBNL1 is measured. Does this perturbation cause a significant change in MBNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4810
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and EGLN3 expression is observed. Does this perturbation lead to a significant difference in EGLN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and EGLN3 expression is observed. Does this perturbation lead to a significant difference in EGLN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3313
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of SETX is measured. Determine whether SETX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of SETX is measured. Determine whether SETX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3366
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of S100A11 is measured. Determine whether S100A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of S100A11 is measured. Determine whether S100A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4646
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor VIM-AS1 expression. Decide whether this perturbation leads to a significant alteration in VIM-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor VIM-AS1 expression. Decide whether this perturbation leads to a significant alteration in VIM-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":488
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor CTNNB1 expression. Decide whether this perturbation leads to a significant alteration in CTNNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor CTNNB1 expression. Decide whether this perturbation leads to a significant alteration in CTNNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2458
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and GALNT7 expression is measured. Determine whether GALNT7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and GALNT7 expression is measured. Determine whether GALNT7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4389
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of IFNGR1 is measured. Does this perturbation cause a significant change in IFNGR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of IFNGR1 is measured. Does this perturbation cause a significant change in IFNGR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2650
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RP11-65L19.4 expression is measured. Determine whether RP11-65L19.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RP11-65L19.4 expression is measured. Determine whether RP11-65L19.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in PLB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in PLB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4955
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and ARHGAP30 expression is measured. Determine whether ARHGAP30 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and ARHGAP30 expression is measured. Determine whether ARHGAP30 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1479
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of CD9. Does this perturbation cause a significant change in CD9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of CD9. Does this perturbation cause a significant change in CD9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":424
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in VAMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in VAMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2905
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of AFF1. Does this perturbation cause a significant change in AFF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of AFF1. Does this perturbation cause a significant change in AFF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2914
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2307
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of PSORS1C1 is measured. Does this perturbation cause a significant change in PSORS1C1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of PSORS1C1 is measured. Does this perturbation cause a significant change in PSORS1C1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2270
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and FCGRT expression is observed. Does this perturbation lead to a significant difference in FCGRT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and FCGRT expression is observed. Does this perturbation lead to a significant difference in FCGRT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3533
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and ACSM3 expression is measured. Determine whether ACSM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and ACSM3 expression is measured. Determine whether ACSM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2219
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of PTAR1. Does perturbing SLC39A7 lead to a significant change in PTAR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of PTAR1. Does perturbing SLC39A7 lead to a significant change in PTAR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2101
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and GNPTG expression is measured. Determine whether GNPTG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and GNPTG expression is measured. Determine whether GNPTG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3099
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of ZEB2. Does perturbing IDH3A lead to a significant change in ZEB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of ZEB2. Does perturbing IDH3A lead to a significant change in ZEB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":961
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and PBDC1 expression is measured. Determine whether PBDC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and PBDC1 expression is measured. Determine whether PBDC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":609
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ZXDA expression is measured. Determine whether ZXDA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ZXDA expression is measured. Determine whether ZXDA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3939
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and PDK2 expression is measured. Determine whether PDK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and PDK2 expression is measured. Determine whether PDK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2169
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in CHST12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in CHST12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3465
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4574
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of PBDC1 is measured. Determine whether PBDC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of PBDC1 is measured. Determine whether PBDC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":606
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":315
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ARHGAP6 is measured. Determine whether ARHGAP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ARHGAP6 is measured. Determine whether ARHGAP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3906
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in RTN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in RTN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2065
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and HLA-AS1 expression is quantified. Does this perturbation result in a significant change in HLA-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and HLA-AS1 expression is quantified. Does this perturbation result in a significant change in HLA-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":762
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and DDIT4 expression is quantified. Does this perturbation result in a significant change in DDIT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and DDIT4 expression is quantified. Does this perturbation result in a significant change in DDIT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1822
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ARHGAP6 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ARHGAP6 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3908
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and KCNE3 expression is observed. Does this perturbation lead to a significant difference in KCNE3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and KCNE3 expression is observed. Does this perturbation lead to a significant difference in KCNE3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1013
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RP11-65L19.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-65L19.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RP11-65L19.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-65L19.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of PDRG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of PDRG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4157
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and UHRF1BP1L expression is quantified. Does this perturbation result in a significant change in UHRF1BP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and UHRF1BP1L expression is quantified. Does this perturbation result in a significant change in UHRF1BP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":242
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and ARSA expression is observed. Does this perturbation lead to a significant difference in ARSA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and ARSA expression is observed. Does this perturbation lead to a significant difference in ARSA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":683
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and IL18R1 expression is quantified. Does this perturbation result in a significant change in IL18R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and IL18R1 expression is quantified. Does this perturbation result in a significant change in IL18R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":352
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of UBE2V1 is measured. Determine whether UBE2V1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of UBE2V1 is measured. Determine whether UBE2V1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1706
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of SLC37A1 is measured. Determine whether SLC37A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of SLC37A1 is measured. Determine whether SLC37A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1156
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of EXOC3L2. Does perturbing PSMD4 lead to a significant change in EXOC3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of EXOC3L2. Does perturbing PSMD4 lead to a significant change in EXOC3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3351
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and EIF3A expression is measured. Determine whether EIF3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and EIF3A expression is measured. Determine whether EIF3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4809
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of CDCA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of CDCA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4117
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and RP11-16E12.1 expression is measured. Determine whether RP11-16E12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and RP11-16E12.1 expression is measured. Determine whether RP11-16E12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3239
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of PSORS1C1. Does perturbing NEDD8 lead to a significant change in PSORS1C1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of PSORS1C1. Does perturbing NEDD8 lead to a significant change in PSORS1C1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2271
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of H1FX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of H1FX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4677
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of FAM212A. Does this perturbation cause a significant change in FAM212A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of FAM212A. Does this perturbation cause a significant change in FAM212A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2234
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor RP11-445H22.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-445H22.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor RP11-445H22.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-445H22.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3818
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of BRWD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of BRWD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":737
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of STK17B is measured. Determine whether STK17B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of STK17B is measured. Determine whether STK17B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4856
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and MED13 expression is observed. Does this perturbation lead to a significant difference in MED13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and MED13 expression is observed. Does this perturbation lead to a significant difference in MED13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4313
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor NSD1 expression. Decide whether this perturbation leads to a significant alteration in NSD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor NSD1 expression. Decide whether this perturbation leads to a significant alteration in NSD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1348
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and ATP6V1B2 expression is measured. Determine whether ATP6V1B2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and ATP6V1B2 expression is measured. Determine whether ATP6V1B2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1609
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of WARS. Does this perturbation cause a significant change in WARS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of WARS. Does this perturbation cause a significant change in WARS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4884
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor RP11-423O2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-423O2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor RP11-423O2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-423O2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":308
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of AC015987.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of AC015987.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2257
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and IFNGR1 expression is measured. Determine whether IFNGR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and IFNGR1 expression is measured. Determine whether IFNGR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2659
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in TOPBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in TOPBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2895
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of LDLR. Does this perturbation cause a significant change in LDLR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of LDLR. Does this perturbation cause a significant change in LDLR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":494
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in HP1BP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in HP1BP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":615
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in CASP4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in CASP4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in IL8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in IL8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1255
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of C3AR1 is measured. Does this perturbation cause a significant change in C3AR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of C3AR1 is measured. Does this perturbation cause a significant change in C3AR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3400
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of PCK2. Does this perturbation cause a significant change in PCK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of PCK2. Does this perturbation cause a significant change in PCK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3014
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of SLC37A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of SLC37A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1157
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and DDX6 expression is quantified. Does this perturbation result in a significant change in DDX6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and DDX6 expression is quantified. Does this perturbation result in a significant change in DDX6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":522
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of RP11-138C9.1 is measured. Does this perturbation cause a significant change in RP11-138C9.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of RP11-138C9.1 is measured. Does this perturbation cause a significant change in RP11-138C9.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":830
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor LINC01031 expression. Decide whether this perturbation leads to a significant alteration in LINC01031 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor LINC01031 expression. Decide whether this perturbation leads to a significant alteration in LINC01031 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4248
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of KIAA1731 is measured. Determine whether KIAA1731 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of KIAA1731 is measured. Determine whether KIAA1731 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4896
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and ZCCHC11 expression is quantified. Does this perturbation result in a significant change in ZCCHC11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and ZCCHC11 expression is quantified. Does this perturbation result in a significant change in ZCCHC11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4992
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor CTD-2521M24.9 expression. Decide whether this perturbation leads to a significant alteration in CTD-2521M24.9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor CTD-2521M24.9 expression. Decide whether this perturbation leads to a significant alteration in CTD-2521M24.9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2998
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of LINC01137 is measured. Does this perturbation cause a significant change in LINC01137 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of LINC01137 is measured. Does this perturbation cause a significant change in LINC01137 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4660
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor NCKAP1L expression. Decide whether this perturbation leads to a significant alteration in NCKAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor NCKAP1L expression. Decide whether this perturbation leads to a significant alteration in NCKAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":448
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of RP11-360L9.8. Does this perturbation cause a significant change in RP11-360L9.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of RP11-360L9.8. Does this perturbation cause a significant change in RP11-360L9.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4294
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of POLR2J3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of POLR2J3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3797
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and OBSCN expression is measured. Determine whether OBSCN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and OBSCN expression is measured. Determine whether OBSCN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3829
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of SP100. Does this perturbation cause a significant change in SP100 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of SP100. Does this perturbation cause a significant change in SP100 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1144
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and SLFNL1 expression is observed. Does this perturbation lead to a significant difference in SLFNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and SLFNL1 expression is observed. Does this perturbation lead to a significant difference in SLFNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":453
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of ACE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of ACE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2577
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor RP11-16E12.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-16E12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor RP11-16E12.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-16E12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3238
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of CEBPG. Does perturbing ZNF326 lead to a significant change in CEBPG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of CEBPG. Does perturbing ZNF326 lead to a significant change in CEBPG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ROBO1. Does this perturbation cause a significant change in ROBO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ROBO1. Does this perturbation cause a significant change in ROBO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3944
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of RP11-24F11.2. Does perturbing MRGBP lead to a significant change in RP11-24F11.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of RP11-24F11.2. Does perturbing MRGBP lead to a significant change in RP11-24F11.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1491
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of CTD-2020K17.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of CTD-2020K17.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4197
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of ATP2A3 is measured. Determine whether ATP2A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of ATP2A3 is measured. Determine whether ATP2A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1836
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and PDRG1 expression is observed. Does this perturbation lead to a significant difference in PDRG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and PDRG1 expression is observed. Does this perturbation lead to a significant difference in PDRG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4153
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and ESCO1 expression is quantified. Does this perturbation result in a significant change in ESCO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and ESCO1 expression is quantified. Does this perturbation result in a significant change in ESCO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":862
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of ZP3 is measured. Does this perturbation cause a significant change in ZP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of ZP3 is measured. Does this perturbation cause a significant change in ZP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2540
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of LTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of LTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4707
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor RP11-247A12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-247A12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor RP11-247A12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-247A12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1668
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of SPAST. Does perturbing SEC61B lead to a significant change in SPAST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of SPAST. Does perturbing SEC61B lead to a significant change in SPAST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2841
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of RNF8 is measured. Does this perturbation cause a significant change in RNF8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of RNF8 is measured. Does this perturbation cause a significant change in RNF8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3180
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and LINC01137 expression is observed. Does this perturbation lead to a significant difference in LINC01137 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and LINC01137 expression is observed. Does this perturbation lead to a significant difference in LINC01137 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4663
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and PTAR1 expression is measured. Determine whether PTAR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and PTAR1 expression is measured. Determine whether PTAR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2109
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1693
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of MBNL1. Does perturbing XRN1 lead to a significant change in MBNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of MBNL1. Does perturbing XRN1 lead to a significant change in MBNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4811
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of P4HB. Does this perturbation cause a significant change in P4HB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of P4HB. Does this perturbation cause a significant change in P4HB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4614
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of TLK2. Does this perturbation cause a significant change in TLK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of TLK2. Does this perturbation cause a significant change in TLK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1994
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of CTNNB1 is measured. Does this perturbation cause a significant change in CTNNB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of CTNNB1 is measured. Does this perturbation cause a significant change in CTNNB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2450
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and RP11-254F7.4 expression is quantified. Does this perturbation result in a significant change in RP11-254F7.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and RP11-254F7.4 expression is quantified. Does this perturbation result in a significant change in RP11-254F7.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2392
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and SLC25A35 expression is measured. Determine whether SLC25A35 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and SLC25A35 expression is measured. Determine whether SLC25A35 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3159
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in RP11-363D14.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in RP11-363D14.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3055
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of ANKRD33. Does perturbing COPB1 lead to a significant change in ANKRD33 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of ANKRD33. Does perturbing COPB1 lead to a significant change in ANKRD33 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4181
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor SNHG10 expression. Decide whether this perturbation leads to a significant alteration in SNHG10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor SNHG10 expression. Decide whether this perturbation leads to a significant alteration in SNHG10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1888
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of UBE3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of UBE3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1227
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of SLC27A2. Does perturbing TIMM44 lead to a significant change in SLC27A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of SLC27A2. Does perturbing TIMM44 lead to a significant change in SLC27A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3681
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of SETD5-AS1 is measured. Determine whether SETD5-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of SETD5-AS1 is measured. Determine whether SETD5-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1186
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in SLC26A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in SLC26A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2195
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3075
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of LAMP2. Does this perturbation cause a significant change in LAMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of LAMP2. Does this perturbation cause a significant change in LAMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5044
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of TSC22D4 is measured. Determine whether TSC22D4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of TSC22D4 is measured. Determine whether TSC22D4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3276
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and CMTM6 expression is observed. Does this perturbation lead to a significant difference in CMTM6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and CMTM6 expression is observed. Does this perturbation lead to a significant difference in CMTM6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4913
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of SMIM14. Does this perturbation cause a significant change in SMIM14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of SMIM14. Does this perturbation cause a significant change in SMIM14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3304
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor ANKLE2 expression. Decide whether this perturbation leads to a significant alteration in ANKLE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor ANKLE2 expression. Decide whether this perturbation leads to a significant alteration in ANKLE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2318
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of RDH10 is measured. Does this perturbation cause a significant change in RDH10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of RDH10 is measured. Does this perturbation cause a significant change in RDH10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":140
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of HIST1H2AC. Does this perturbation cause a significant change in HIST1H2AC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of HIST1H2AC. Does this perturbation cause a significant change in HIST1H2AC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3024
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of SNHG10. Does this perturbation cause a significant change in SNHG10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of SNHG10. Does this perturbation cause a significant change in SNHG10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1314
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of DDIT4 is measured. Does this perturbation cause a significant change in DDIT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of DDIT4 is measured. Does this perturbation cause a significant change in DDIT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1820
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of RSAD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of RSAD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4407
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of PITPNB is measured. Does this perturbation cause a significant change in PITPNB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of PITPNB is measured. Does this perturbation cause a significant change in PITPNB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3730
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PSMD14 expression is measured. Determine whether PSMD14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PSMD14 expression is measured. Determine whether PSMD14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3109
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of CDT1 is measured. Does this perturbation cause a significant change in CDT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of CDT1 is measured. Does this perturbation cause a significant change in CDT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5120
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and TLK2 expression is quantified. Does this perturbation result in a significant change in TLK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and TLK2 expression is quantified. Does this perturbation result in a significant change in TLK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4762
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in MED13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in MED13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4315
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of ARHGAP11A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of ARHGAP11A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3727
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and SLC37A1 expression is observed. Does this perturbation lead to a significant difference in SLC37A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and SLC37A1 expression is observed. Does this perturbation lead to a significant difference in SLC37A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1153
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of PPP1R16B is measured. Does this perturbation cause a significant change in PPP1R16B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of PPP1R16B is measured. Does this perturbation cause a significant change in PPP1R16B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":590
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in LINC01031 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in LINC01031 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4245
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and LTN1 expression is measured. Determine whether LTN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and LTN1 expression is measured. Determine whether LTN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3139
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of RILPL2. Does this perturbation cause a significant change in RILPL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of RILPL2. Does this perturbation cause a significant change in RILPL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2804
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of DNTTIP2 is measured. Does this perturbation cause a significant change in DNTTIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of DNTTIP2 is measured. Does this perturbation cause a significant change in DNTTIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":810
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of POU2F2. Does perturbing HARS lead to a significant change in POU2F2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of POU2F2. Does perturbing HARS lead to a significant change in POU2F2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":651
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in UFD1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in UFD1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2505
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and LTN1 expression is observed. Does this perturbation lead to a significant difference in LTN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and LTN1 expression is observed. Does this perturbation lead to a significant difference in LTN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3133
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and CTD-2020K17.1 expression is quantified. Does this perturbation result in a significant change in CTD-2020K17.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and CTD-2020K17.1 expression is quantified. Does this perturbation result in a significant change in CTD-2020K17.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4192
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of SP100. Does perturbing UFL1 lead to a significant change in SP100 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of SP100. Does perturbing UFL1 lead to a significant change in SP100 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1141
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of MANF is measured. Determine whether MANF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of MANF is measured. Determine whether MANF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2076
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of PHF21A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of PHF21A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3857
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of CENPC. Does perturbing PPWD1 lead to a significant change in CENPC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of CENPC. Does perturbing PPWD1 lead to a significant change in CENPC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4451
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of MANF. Does this perturbation cause a significant change in MANF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of MANF. Does this perturbation cause a significant change in MANF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2074
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of HIST1H1E. Does this perturbation cause a significant change in HIST1H1E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of HIST1H1E. Does this perturbation cause a significant change in HIST1H1E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1024
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in KLF3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in KLF3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1985
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and ESCO1 expression is measured. Determine whether ESCO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and ESCO1 expression is measured. Determine whether ESCO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":869
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor HPCAL1 expression. Decide whether this perturbation leads to a significant alteration in HPCAL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor HPCAL1 expression. Decide whether this perturbation leads to a significant alteration in HPCAL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2978
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and MLEC expression is quantified. Does this perturbation result in a significant change in MLEC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and MLEC expression is quantified. Does this perturbation result in a significant change in MLEC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3172
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RGS20. Does perturbing MARS lead to a significant change in RGS20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RGS20. Does perturbing MARS lead to a significant change in RGS20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2711
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in HMGCS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in HMGCS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":375
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and H1FX expression is measured. Determine whether H1FX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and H1FX expression is measured. Determine whether H1FX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4679
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of C6orf120. Does this perturbation cause a significant change in C6orf120 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of C6orf120. Does this perturbation cause a significant change in C6orf120 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2264
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and CHST12 expression is measured. Determine whether CHST12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and CHST12 expression is measured. Determine whether CHST12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3469
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of ZCCHC11. Does perturbing P4HB lead to a significant change in ZCCHC11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of ZCCHC11. Does perturbing P4HB lead to a significant change in ZCCHC11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4991
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and CDRT4 expression is observed. Does this perturbation lead to a significant difference in CDRT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and CDRT4 expression is observed. Does this perturbation lead to a significant difference in CDRT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":283
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of CEBPG is measured. Determine whether CEBPG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of CEBPG is measured. Determine whether CEBPG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and RP11-390B4.5 expression is measured. Determine whether RP11-390B4.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and RP11-390B4.5 expression is measured. Determine whether RP11-390B4.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4839
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor CTSV expression. Decide whether this perturbation leads to a significant alteration in CTSV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor CTSV expression. Decide whether this perturbation leads to a significant alteration in CTSV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2678
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of RP11-242O24.5. Does this perturbation cause a significant change in RP11-242O24.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of RP11-242O24.5. Does this perturbation cause a significant change in RP11-242O24.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3994
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and NRIP1 expression is measured. Determine whether NRIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and NRIP1 expression is measured. Determine whether NRIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3629
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and QSER1 expression is quantified. Does this perturbation result in a significant change in QSER1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and QSER1 expression is quantified. Does this perturbation result in a significant change in QSER1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5002
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and PLA2G15 expression is quantified. Does this perturbation result in a significant change in PLA2G15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and PLA2G15 expression is quantified. Does this perturbation result in a significant change in PLA2G15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3832
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and TRAPPC10 expression is measured. Determine whether TRAPPC10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and TRAPPC10 expression is measured. Determine whether TRAPPC10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1859
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of RSAD2 is measured. Does this perturbation cause a significant change in RSAD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of RSAD2 is measured. Does this perturbation cause a significant change in RSAD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4400
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of FOXO6 is measured. Determine whether FOXO6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of FOXO6 is measured. Determine whether FOXO6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4126
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2129
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of KDM1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of KDM1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1167
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of RP11-38P22.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of RP11-38P22.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1057
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor BACH2 expression. Decide whether this perturbation leads to a significant alteration in BACH2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor BACH2 expression. Decide whether this perturbation leads to a significant alteration in BACH2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3478
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and VIMP expression is quantified. Does this perturbation result in a significant change in VIMP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and VIMP expression is quantified. Does this perturbation result in a significant change in VIMP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":972
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of P4HA2 is measured. Does this perturbation cause a significant change in P4HA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of P4HA2 is measured. Does this perturbation cause a significant change in P4HA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2400
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of RP11-360L9.8 is measured. Determine whether RP11-360L9.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of RP11-360L9.8 is measured. Determine whether RP11-360L9.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2796
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in TTC32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in TTC32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3215
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of RNF139-AS1 is measured. Determine whether RNF139-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of RNF139-AS1 is measured. Determine whether RNF139-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2526
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of CDKN2C is measured. Determine whether CDKN2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of CDKN2C is measured. Determine whether CDKN2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2816
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":313
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of ASPM is measured. Does this perturbation cause a significant change in ASPM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of ASPM is measured. Does this perturbation cause a significant change in ASPM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2660
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and RP11-61E11.1 expression is observed. Does this perturbation lead to a significant difference in RP11-61E11.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and RP11-61E11.1 expression is observed. Does this perturbation lead to a significant difference in RP11-61E11.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1423
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of AC005540.3 is measured. Determine whether AC005540.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of AC005540.3 is measured. Determine whether AC005540.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4416
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor CD83 expression. Decide whether this perturbation leads to a significant alteration in CD83 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor CD83 expression. Decide whether this perturbation leads to a significant alteration in CD83 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2698
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of DNTTIP2. Does this perturbation cause a significant change in DNTTIP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of DNTTIP2. Does this perturbation cause a significant change in DNTTIP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":814
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in RP11-304M2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in RP11-304M2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4535
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of STK17B is measured. Does this perturbation cause a significant change in STK17B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of STK17B is measured. Does this perturbation cause a significant change in STK17B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4850
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor RNF19A expression. Decide whether this perturbation leads to a significant alteration in RNF19A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor RNF19A expression. Decide whether this perturbation leads to a significant alteration in RNF19A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3768
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of CTD-2267D19.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of CTD-2267D19.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1547
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in PLA2G15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in PLA2G15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3835
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of ARSA is measured. Does this perturbation cause a significant change in ARSA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of ARSA is measured. Does this perturbation cause a significant change in ARSA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":680
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of KCTD19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of KCTD19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2687
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and TGOLN2 expression is quantified. Does this perturbation result in a significant change in TGOLN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and TGOLN2 expression is quantified. Does this perturbation result in a significant change in TGOLN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5092
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of RP11-16E12.1 is measured. Determine whether RP11-16E12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of RP11-16E12.1 is measured. Determine whether RP11-16E12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3236
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of PTBP3. Does this perturbation cause a significant change in PTBP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of PTBP3. Does this perturbation cause a significant change in PTBP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":664
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of TSNAXIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of TSNAXIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":757
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of STARD9. Does this perturbation cause a significant change in STARD9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of STARD9. Does this perturbation cause a significant change in STARD9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4604
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of MLEC. Does this perturbation cause a significant change in MLEC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of MLEC. Does this perturbation cause a significant change in MLEC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3174
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of WHAMM is measured. Does this perturbation cause a significant change in WHAMM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of WHAMM is measured. Does this perturbation cause a significant change in WHAMM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":780
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and DNASE2 expression is quantified. Does this perturbation result in a significant change in DNASE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and DNASE2 expression is quantified. Does this perturbation result in a significant change in DNASE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1632
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and C3AR1 expression is quantified. Does this perturbation result in a significant change in C3AR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and C3AR1 expression is quantified. Does this perturbation result in a significant change in C3AR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3402
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and CTD-2001C12.1 expression is quantified. Does this perturbation result in a significant change in CTD-2001C12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and CTD-2001C12.1 expression is quantified. Does this perturbation result in a significant change in CTD-2001C12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":572
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and RP11-789C1.1 expression is observed. Does this perturbation lead to a significant difference in RP11-789C1.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and RP11-789C1.1 expression is observed. Does this perturbation lead to a significant difference in RP11-789C1.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":943
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of DUSP21. Does this perturbation cause a significant change in DUSP21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of DUSP21. Does this perturbation cause a significant change in DUSP21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2744
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of BAMBI. Does this perturbation cause a significant change in BAMBI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of BAMBI. Does this perturbation cause a significant change in BAMBI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1274
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of ARHGDIB is measured. Determine whether ARHGDIB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of ARHGDIB is measured. Determine whether ARHGDIB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1966
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of RP11-573D15.2 is measured. Does this perturbation cause a significant change in RP11-573D15.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of RP11-573D15.2 is measured. Does this perturbation cause a significant change in RP11-573D15.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3880
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in NAV2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in NAV2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4865
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and RP11-138C9.1 expression is quantified. Does this perturbation result in a significant change in RP11-138C9.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and RP11-138C9.1 expression is quantified. Does this perturbation result in a significant change in RP11-138C9.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":832
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of SKIL is measured. Determine whether SKIL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of SKIL is measured. Determine whether SKIL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2946
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of PELO indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of PELO indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2117
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor HIST1H2BC expression. Decide whether this perturbation leads to a significant alteration in HIST1H2BC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor HIST1H2BC expression. Decide whether this perturbation leads to a significant alteration in HIST1H2BC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4778
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of PTGS1 is measured. Determine whether PTGS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of PTGS1 is measured. Determine whether PTGS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3486
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4750
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of CLDN11 is measured. Determine whether CLDN11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of CLDN11 is measured. Determine whether CLDN11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4546
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of USP37. Does perturbing SYVN1 lead to a significant change in USP37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of USP37. Does perturbing SYVN1 lead to a significant change in USP37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1731
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and TOPBP1 expression is quantified. Does this perturbation result in a significant change in TOPBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and TOPBP1 expression is quantified. Does this perturbation result in a significant change in TOPBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3802
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of ESCO1. Does perturbing AMIGO3 lead to a significant change in ESCO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of ESCO1. Does perturbing AMIGO3 lead to a significant change in ESCO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":861
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of PELO. Does perturbing SLC39A7 lead to a significant change in PELO expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of PELO. Does perturbing SLC39A7 lead to a significant change in PELO expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2111
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and PIK3IP1 expression is observed. Does this perturbation lead to a significant difference in PIK3IP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and PIK3IP1 expression is observed. Does this perturbation lead to a significant difference in PIK3IP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2863
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of DSC2. Does perturbing UFM1 lead to a significant change in DSC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of DSC2. Does perturbing UFM1 lead to a significant change in DSC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4091
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and AKAP11 expression is observed. Does this perturbation lead to a significant difference in AKAP11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and AKAP11 expression is observed. Does this perturbation lead to a significant difference in AKAP11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1923
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and WHAMM expression is quantified. Does this perturbation result in a significant change in WHAMM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and WHAMM expression is quantified. Does this perturbation result in a significant change in WHAMM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":782
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of PIK3IP1 is measured. Determine whether PIK3IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of PIK3IP1 is measured. Determine whether PIK3IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2866
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of HP1BP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of HP1BP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":617
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in S100A10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in S100A10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4875
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of ZNF292. Does perturbing SEL1L lead to a significant change in ZNF292 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of ZNF292. Does perturbing SEL1L lead to a significant change in ZNF292 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1501
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of RP11-360L9.8. Does perturbing HSD17B12 lead to a significant change in RP11-360L9.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of RP11-360L9.8. Does perturbing HSD17B12 lead to a significant change in RP11-360L9.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2791
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of SOBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of SOBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3637
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of C6orf48 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of C6orf48 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of GRN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of GRN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4337
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of HLTF is measured. Does this perturbation cause a significant change in HLTF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of HLTF is measured. Does this perturbation cause a significant change in HLTF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2480
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and TAP1 expression is observed. Does this perturbation lead to a significant difference in TAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and TAP1 expression is observed. Does this perturbation lead to a significant difference in TAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4713
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of DOK3. Does perturbing OST4 lead to a significant change in DOK3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of DOK3. Does perturbing OST4 lead to a significant change in DOK3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":261
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and ZNF280B expression is observed. Does this perturbation lead to a significant difference in ZNF280B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and ZNF280B expression is observed. Does this perturbation lead to a significant difference in ZNF280B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1283
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of RP11-381O7.3. Does perturbing SEL1L lead to a significant change in RP11-381O7.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of RP11-381O7.3. Does perturbing SEL1L lead to a significant change in RP11-381O7.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1551
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of PITPNB. Does this perturbation cause a significant change in PITPNB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of PITPNB. Does this perturbation cause a significant change in PITPNB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3734
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of ARSA. Does perturbing SLMO2 lead to a significant change in ARSA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of ARSA. Does perturbing SLMO2 lead to a significant change in ARSA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":681
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in GUSB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in GUSB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1405
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor KIF4A expression. Decide whether this perturbation leads to a significant alteration in KIF4A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor KIF4A expression. Decide whether this perturbation leads to a significant alteration in KIF4A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2588
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and NXF1 expression is measured. Determine whether NXF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and NXF1 expression is measured. Determine whether NXF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3119
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of USP34. Does this perturbation cause a significant change in USP34 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of USP34. Does this perturbation cause a significant change in USP34 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4364
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of TFPI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of TFPI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3917
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and HOTAIRM1 expression is measured. Determine whether HOTAIRM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and HOTAIRM1 expression is measured. Determine whether HOTAIRM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1269
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of HERC2. Does this perturbation cause a significant change in HERC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of HERC2. Does this perturbation cause a significant change in HERC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":954
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of TSC22D4. Does perturbing HSPA5 lead to a significant change in TSC22D4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of TSC22D4. Does perturbing HSPA5 lead to a significant change in TSC22D4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3271
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1950
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of SMCO1. Does this perturbation cause a significant change in SMCO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of SMCO1. Does this perturbation cause a significant change in SMCO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4494
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of HAGH. Does this perturbation cause a significant change in HAGH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of HAGH. Does this perturbation cause a significant change in HAGH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2634
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of QSER1 is measured. Determine whether QSER1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of QSER1 is measured. Determine whether QSER1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5006
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and ZEB1 expression is quantified. Does this perturbation result in a significant change in ZEB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and ZEB1 expression is quantified. Does this perturbation result in a significant change in ZEB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1382
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of CTC-308K20.1 is measured. Determine whether CTC-308K20.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of CTC-308K20.1 is measured. Determine whether CTC-308K20.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5136
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ARHGAP6 expression is observed. Does this perturbation lead to a significant difference in ARHGAP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ARHGAP6 expression is observed. Does this perturbation lead to a significant difference in ARHGAP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3903
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of SDF4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of SDF4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1777
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and NUF2 expression is measured. Determine whether NUF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and NUF2 expression is measured. Determine whether NUF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1399
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of KIF4A is measured. Does this perturbation cause a significant change in KIF4A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of KIF4A is measured. Does this perturbation cause a significant change in KIF4A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2580
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor FYTTD1 expression. Decide whether this perturbation leads to a significant alteration in FYTTD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor FYTTD1 expression. Decide whether this perturbation leads to a significant alteration in FYTTD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2368
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and PLB1 expression is observed. Does this perturbation lead to a significant difference in PLB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and PLB1 expression is observed. Does this perturbation lead to a significant difference in PLB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4953
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of AC015987.2 is measured. Does this perturbation cause a significant change in AC015987.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of AC015987.2 is measured. Does this perturbation cause a significant change in AC015987.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2010
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of PPP4R2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of PPP4R2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2377
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of LAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of LAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5047
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and EIF4B expression is measured. Determine whether EIF4B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and EIF4B expression is measured. Determine whether EIF4B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4969
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of KIAA1586 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of KIAA1586 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4657
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and GPR146 expression is measured. Determine whether GPR146 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and GPR146 expression is measured. Determine whether GPR146 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5089
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in RP11-471M2.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in RP11-471M2.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2595
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of NOXA1. Does this perturbation cause a significant change in NOXA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of NOXA1. Does this perturbation cause a significant change in NOXA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1414
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and SETX expression is observed. Does this perturbation lead to a significant difference in SETX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and SETX expression is observed. Does this perturbation lead to a significant difference in SETX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2473
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and STK17B expression is observed. Does this perturbation lead to a significant difference in STK17B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and STK17B expression is observed. Does this perturbation lead to a significant difference in STK17B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4853
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of RP11-573D15.9. Does perturbing QARS lead to a significant change in RP11-573D15.9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of RP11-573D15.9. Does perturbing QARS lead to a significant change in RP11-573D15.9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1291
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and DOCK11 expression is measured. Determine whether DOCK11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and DOCK11 expression is measured. Determine whether DOCK11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":369
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and LTBP1 expression is observed. Does this perturbation lead to a significant difference in LTBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and LTBP1 expression is observed. Does this perturbation lead to a significant difference in LTBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1803
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and S100A11 expression is observed. Does this perturbation lead to a significant difference in S100A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and S100A11 expression is observed. Does this perturbation lead to a significant difference in S100A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3253
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of HLA-E is measured. Determine whether HLA-E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of HLA-E is measured. Determine whether HLA-E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3266
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of EBI3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of EBI3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1657
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of GPR146 is measured. Does this perturbation cause a significant change in GPR146 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of GPR146 is measured. Does this perturbation cause a significant change in GPR146 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5080
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in RP11-499F3.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in RP11-499F3.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2885
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and CLINT1 expression is quantified. Does this perturbation result in a significant change in CLINT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and CLINT1 expression is quantified. Does this perturbation result in a significant change in CLINT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":432
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and SERPINH1 expression is measured. Determine whether SERPINH1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and SERPINH1 expression is measured. Determine whether SERPINH1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1649
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of MS4A6E. Does perturbing SEC61A1 lead to a significant change in MS4A6E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of MS4A6E. Does perturbing SEC61A1 lead to a significant change in MS4A6E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":341
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in ATP6AP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in ATP6AP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1625
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and KANSL1L expression is observed. Does this perturbation lead to a significant difference in KANSL1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and KANSL1L expression is observed. Does this perturbation lead to a significant difference in KANSL1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":643
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and LIMS1 expression is observed. Does this perturbation lead to a significant difference in LIMS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and LIMS1 expression is observed. Does this perturbation lead to a significant difference in LIMS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3373
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ARHGAP6. Does perturbing KCTD16 lead to a significant change in ARHGAP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ARHGAP6. Does perturbing KCTD16 lead to a significant change in ARHGAP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3421
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":314
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of PHF3. Does this perturbation cause a significant change in PHF3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of PHF3. Does this perturbation cause a significant change in PHF3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of IRF7. Does this perturbation cause a significant change in IRF7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of IRF7. Does this perturbation cause a significant change in IRF7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":534
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of RP11-2H8.2 is measured. Determine whether RP11-2H8.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of RP11-2H8.2 is measured. Determine whether RP11-2H8.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3596
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor KANSL1L expression. Decide whether this perturbation leads to a significant alteration in KANSL1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor KANSL1L expression. Decide whether this perturbation leads to a significant alteration in KANSL1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":648
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of CRNDE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of CRNDE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1977
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and H1FX expression is quantified. Does this perturbation result in a significant change in H1FX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and H1FX expression is quantified. Does this perturbation result in a significant change in H1FX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4672
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and RP11-242O24.5 expression is observed. Does this perturbation lead to a significant difference in RP11-242O24.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and RP11-242O24.5 expression is observed. Does this perturbation lead to a significant difference in RP11-242O24.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3993
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor RP11-119J18.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-119J18.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor RP11-119J18.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-119J18.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2448
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and WHSC1 expression is quantified. Does this perturbation result in a significant change in WHSC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and WHSC1 expression is quantified. Does this perturbation result in a significant change in WHSC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1482
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and NFE2 expression is observed. Does this perturbation lead to a significant difference in NFE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and NFE2 expression is observed. Does this perturbation lead to a significant difference in NFE2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":213
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in GDF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in GDF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":395
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor KLK1 expression. Decide whether this perturbation leads to a significant alteration in KLK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor KLK1 expression. Decide whether this perturbation leads to a significant alteration in KLK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":208
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of KLK1. Does perturbing DDIT3 lead to a significant change in KLK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of KLK1. Does perturbing DDIT3 lead to a significant change in KLK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":201
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2128
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of TRAPPC10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of TRAPPC10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1857
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of AC096559.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of AC096559.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1877
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of KIF4A is measured. Determine whether KIF4A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of KIF4A is measured. Determine whether KIF4A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2586
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of ACRV1. Does perturbing DDOST lead to a significant change in ACRV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of ACRV1. Does perturbing DDOST lead to a significant change in ACRV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3891
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of GOT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of GOT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1117
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of RP11-61E11.1. Does perturbing SAMM50 lead to a significant change in RP11-61E11.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of RP11-61E11.1. Does perturbing SAMM50 lead to a significant change in RP11-61E11.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1421
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of LAMP2 is measured. Does this perturbation cause a significant change in LAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of LAMP2 is measured. Does this perturbation cause a significant change in LAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2770
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and POU2F2 expression is observed. Does this perturbation lead to a significant difference in POU2F2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and POU2F2 expression is observed. Does this perturbation lead to a significant difference in POU2F2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":653
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of PPP1R16B is measured. Determine whether PPP1R16B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of PPP1R16B is measured. Determine whether PPP1R16B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4486
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of C19orf59 is measured. Determine whether C19orf59 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of C19orf59 is measured. Determine whether C19orf59 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2346
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of CTC-308K20.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of CTC-308K20.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5137
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of NTRK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of NTRK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4037
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in NAV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in NAV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4465
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and TRIM38 expression is quantified. Does this perturbation result in a significant change in TRIM38 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and TRIM38 expression is quantified. Does this perturbation result in a significant change in TRIM38 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3382
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of HERC2 is measured. Determine whether HERC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of HERC2 is measured. Determine whether HERC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":956
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of PGM3. Does this perturbation cause a significant change in PGM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of PGM3. Does this perturbation cause a significant change in PGM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2084
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and RP11-360L9.8 expression is measured. Determine whether RP11-360L9.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and RP11-360L9.8 expression is measured. Determine whether RP11-360L9.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2799
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4283
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2302
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of CENPC is measured. Does this perturbation cause a significant change in CENPC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of CENPC is measured. Does this perturbation cause a significant change in CENPC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4450
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and CMTM6 expression is measured. Determine whether CMTM6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and CMTM6 expression is measured. Determine whether CMTM6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4919
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of PSMC1. Does this perturbation cause a significant change in PSMC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of PSMC1. Does this perturbation cause a significant change in PSMC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2824
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of EGLN3 is measured. Determine whether EGLN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of EGLN3 is measured. Determine whether EGLN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3316
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and HERPUD1 expression is observed. Does this perturbation lead to a significant difference in HERPUD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and HERPUD1 expression is observed. Does this perturbation lead to a significant difference in HERPUD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4433
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of TOB2. Does perturbing IDH3A lead to a significant change in TOB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of TOB2. Does perturbing IDH3A lead to a significant change in TOB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":981
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and CDT1 expression is observed. Does this perturbation lead to a significant difference in CDT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and CDT1 expression is observed. Does this perturbation lead to a significant difference in CDT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5123
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and SP100 expression is measured. Determine whether SP100 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and SP100 expression is measured. Determine whether SP100 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1149
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of SEPT5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of SEPT5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3547
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of FCGRT is measured. Does this perturbation cause a significant change in FCGRT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of FCGRT is measured. Does this perturbation cause a significant change in FCGRT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3530
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and S100A11 expression is measured. Determine whether S100A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and S100A11 expression is measured. Determine whether S100A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4649
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and SEC23IP expression is quantified. Does this perturbation result in a significant change in SEC23IP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and SEC23IP expression is quantified. Does this perturbation result in a significant change in SEC23IP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3972
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of TRPM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of TRPM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3847
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of PDE3B. Does perturbing DNAJC19 lead to a significant change in PDE3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of PDE3B. Does perturbing DNAJC19 lead to a significant change in PDE3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4781
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of CTCFL. Does this perturbation cause a significant change in CTCFL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of CTCFL. Does this perturbation cause a significant change in CTCFL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2604
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and TNFRSF10B expression is observed. Does this perturbation lead to a significant difference in TNFRSF10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and TNFRSF10B expression is observed. Does this perturbation lead to a significant difference in TNFRSF10B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2283
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of RSAD2 is measured. Does this perturbation cause a significant change in RSAD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of RSAD2 is measured. Does this perturbation cause a significant change in RSAD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1460
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and CTSF expression is observed. Does this perturbation lead to a significant difference in CTSF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and CTSF expression is observed. Does this perturbation lead to a significant difference in CTSF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":153
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of ZNF341. Does this perturbation cause a significant change in ZNF341 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of ZNF341. Does this perturbation cause a significant change in ZNF341 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3774
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and HRK expression is quantified. Does this perturbation result in a significant change in HRK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and HRK expression is quantified. Does this perturbation result in a significant change in HRK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1042
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and ZNF789 expression is observed. Does this perturbation lead to a significant difference in ZNF789 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and ZNF789 expression is observed. Does this perturbation lead to a significant difference in ZNF789 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3223
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and CTSF expression is quantified. Does this perturbation result in a significant change in CTSF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and CTSF expression is quantified. Does this perturbation result in a significant change in CTSF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":152
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and USP34 expression is quantified. Does this perturbation result in a significant change in USP34 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and USP34 expression is quantified. Does this perturbation result in a significant change in USP34 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4362
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of AFF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of AFF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2917
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and TNFRSF10B expression is measured. Determine whether TNFRSF10B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and TNFRSF10B expression is measured. Determine whether TNFRSF10B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3869
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and PIK3R3 expression is measured. Determine whether PIK3R3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and PIK3R3 expression is measured. Determine whether PIK3R3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4029
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and C3AR1 expression is measured. Determine whether C3AR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and C3AR1 expression is measured. Determine whether C3AR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3409
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of ZNF280B. Does perturbing SOCS1 lead to a significant change in ZNF280B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of ZNF280B. Does perturbing SOCS1 lead to a significant change in ZNF280B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1101
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and KCNH7 expression is quantified. Does this perturbation result in a significant change in KCNH7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and KCNH7 expression is quantified. Does this perturbation result in a significant change in KCNH7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1782
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of EPB42 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of EPB42 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1717
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and RP11-61E11.1 expression is measured. Determine whether RP11-61E11.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and RP11-61E11.1 expression is measured. Determine whether RP11-61E11.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1429
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in SMIM14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in SMIM14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3305
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of CD46. Does perturbing CHERP lead to a significant change in CD46 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of CD46. Does perturbing CHERP lead to a significant change in CD46 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4211
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of VAMP2. Does this perturbation cause a significant change in VAMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of VAMP2. Does this perturbation cause a significant change in VAMP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2904
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of HIST1H2BC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of HIST1H2BC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4777
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and IFNGR1 expression is observed. Does this perturbation lead to a significant difference in IFNGR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and IFNGR1 expression is observed. Does this perturbation lead to a significant difference in IFNGR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2653
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and RP11-863K10.7 expression is observed. Does this perturbation lead to a significant difference in RP11-863K10.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and RP11-863K10.7 expression is observed. Does this perturbation lead to a significant difference in RP11-863K10.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":933
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of RDH10. Does this perturbation cause a significant change in RDH10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of RDH10. Does this perturbation cause a significant change in RDH10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":144
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":318
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and APOBEC3D expression is measured. Determine whether APOBEC3D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and APOBEC3D expression is measured. Determine whether APOBEC3D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3579
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of TUBA1C. Does perturbing SRP72 lead to a significant change in TUBA1C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of TUBA1C. Does perturbing SRP72 lead to a significant change in TUBA1C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3391
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and PCF11 expression is quantified. Does this perturbation result in a significant change in PCF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and PCF11 expression is quantified. Does this perturbation result in a significant change in PCF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5062
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of CENPC is measured. Determine whether CENPC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of CENPC is measured. Determine whether CENPC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4456
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and HPCAL1 expression is observed. Does this perturbation lead to a significant difference in HPCAL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and HPCAL1 expression is observed. Does this perturbation lead to a significant difference in HPCAL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2973
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in USP34 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in USP34 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4365
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and CDKN2C expression is quantified. Does this perturbation result in a significant change in CDKN2C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and CDKN2C expression is quantified. Does this perturbation result in a significant change in CDKN2C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2812
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of AC018878.3 is measured. Determine whether AC018878.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of AC018878.3 is measured. Determine whether AC018878.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3286
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of YTHDF2 is measured. Determine whether YTHDF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of YTHDF2 is measured. Determine whether YTHDF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4926
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of RP11-640M9.1. Does this perturbation cause a significant change in RP11-640M9.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of RP11-640M9.1. Does this perturbation cause a significant change in RP11-640M9.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1124
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and STK17B expression is quantified. Does this perturbation result in a significant change in STK17B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and STK17B expression is quantified. Does this perturbation result in a significant change in STK17B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4852
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and SPCS2 expression is quantified. Does this perturbation result in a significant change in SPCS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and SPCS2 expression is quantified. Does this perturbation result in a significant change in SPCS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":692
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of ATP6V1B2 is measured. Does this perturbation cause a significant change in ATP6V1B2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of ATP6V1B2 is measured. Does this perturbation cause a significant change in ATP6V1B2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1600
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of POU2F2 is measured. Determine whether POU2F2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of POU2F2 is measured. Determine whether POU2F2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":656
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and KCNH7 expression is observed. Does this perturbation lead to a significant difference in KCNH7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and KCNH7 expression is observed. Does this perturbation lead to a significant difference in KCNH7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1783
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and MORF4L2 expression is observed. Does this perturbation lead to a significant difference in MORF4L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and MORF4L2 expression is observed. Does this perturbation lead to a significant difference in MORF4L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2623
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and RP11-334C17.5 expression is measured. Determine whether RP11-334C17.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and RP11-334C17.5 expression is measured. Determine whether RP11-334C17.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1009
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of VIM-AS1. Does this perturbation cause a significant change in VIM-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of VIM-AS1. Does this perturbation cause a significant change in VIM-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":484
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor SETX expression. Decide whether this perturbation leads to a significant alteration in SETX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor SETX expression. Decide whether this perturbation leads to a significant alteration in SETX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3368
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and LRIF1 expression is observed. Does this perturbation lead to a significant difference in LRIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and LRIF1 expression is observed. Does this perturbation lead to a significant difference in LRIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1453
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of KIAA1731 is measured. Does this perturbation cause a significant change in KIAA1731 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of KIAA1731 is measured. Does this perturbation cause a significant change in KIAA1731 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4890
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of KLF6 is measured. Does this perturbation cause a significant change in KLF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of KLF6 is measured. Does this perturbation cause a significant change in KLF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2290
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and KCTD1 expression is quantified. Does this perturbation result in a significant change in KCTD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and KCTD1 expression is quantified. Does this perturbation result in a significant change in KCTD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1372
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2095
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of TSNAXIP1 is measured. Determine whether TSNAXIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of TSNAXIP1 is measured. Determine whether TSNAXIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":756
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and CASP8 expression is measured. Determine whether CASP8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and CASP8 expression is measured. Determine whether CASP8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":229
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of SSBP2 is measured. Does this perturbation cause a significant change in SSBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of SSBP2 is measured. Does this perturbation cause a significant change in SSBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4160
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of ERP29 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of ERP29 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5077
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor SPCS2 expression. Decide whether this perturbation leads to a significant alteration in SPCS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor SPCS2 expression. Decide whether this perturbation leads to a significant alteration in SPCS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":698
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and TMOD3 expression is observed. Does this perturbation lead to a significant difference in TMOD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and TMOD3 expression is observed. Does this perturbation lead to a significant difference in TMOD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1513
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of PCK2 is measured. Determine whether PCK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of PCK2 is measured. Determine whether PCK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":336
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor TMEM87B expression. Decide whether this perturbation leads to a significant alteration in TMEM87B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor TMEM87B expression. Decide whether this perturbation leads to a significant alteration in TMEM87B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":828
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and DST expression is quantified. Does this perturbation result in a significant change in DST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and DST expression is quantified. Does this perturbation result in a significant change in DST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3492
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of TGOLN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of TGOLN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5097
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of EPS15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of EPS15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4847
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor RGS3 expression. Decide whether this perturbation leads to a significant alteration in RGS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor RGS3 expression. Decide whether this perturbation leads to a significant alteration in RGS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2878
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and CD58 expression is observed. Does this perturbation lead to a significant difference in CD58 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and CD58 expression is observed. Does this perturbation lead to a significant difference in CD58 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2493
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of EGLN3. Does perturbing PSMD4 lead to a significant change in EGLN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of EGLN3. Does perturbing PSMD4 lead to a significant change in EGLN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3311
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ZXDA expression is observed. Does this perturbation lead to a significant difference in ZXDA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ZXDA expression is observed. Does this perturbation lead to a significant difference in ZXDA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3933
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and LINC01031 expression is quantified. Does this perturbation result in a significant change in LINC01031 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and LINC01031 expression is quantified. Does this perturbation result in a significant change in LINC01031 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4242
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and RP11-363D14.1 expression is quantified. Does this perturbation result in a significant change in RP11-363D14.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and RP11-363D14.1 expression is quantified. Does this perturbation result in a significant change in RP11-363D14.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3052
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of KCTD1. Does this perturbation cause a significant change in KCTD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of KCTD1. Does this perturbation cause a significant change in KCTD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1374
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor KDM1B expression. Decide whether this perturbation leads to a significant alteration in KDM1B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor KDM1B expression. Decide whether this perturbation leads to a significant alteration in KDM1B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1168
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and AC015987.1 expression is measured. Determine whether AC015987.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and AC015987.1 expression is measured. Determine whether AC015987.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2259
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in SPAST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in SPAST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2845
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor PDRG1 expression. Decide whether this perturbation leads to a significant alteration in PDRG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor PDRG1 expression. Decide whether this perturbation leads to a significant alteration in PDRG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4158
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in H1FX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in H1FX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4675
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor TLK2 expression. Decide whether this perturbation leads to a significant alteration in TLK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor TLK2 expression. Decide whether this perturbation leads to a significant alteration in TLK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4768
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and PDK2 expression is quantified. Does this perturbation result in a significant change in PDK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and PDK2 expression is quantified. Does this perturbation result in a significant change in PDK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2162
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of RBM12B-AS1 is measured. Determine whether RBM12B-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of RBM12B-AS1 is measured. Determine whether RBM12B-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2516
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2726
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of PDK2. Does this perturbation cause a significant change in PDK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of PDK2. Does this perturbation cause a significant change in PDK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2164
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor RP3-465N24.6 expression. Decide whether this perturbation leads to a significant alteration in RP3-465N24.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor RP3-465N24.6 expression. Decide whether this perturbation leads to a significant alteration in RP3-465N24.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3588
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and CPQ expression is measured. Determine whether CPQ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and CPQ expression is measured. Determine whether CPQ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2969
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of STK17B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of STK17B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4857
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of CENPF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of CENPF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4067
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of LPAR5. Does this perturbation cause a significant change in LPAR5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of LPAR5. Does this perturbation cause a significant change in LPAR5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of RP11-2H8.2. Does this perturbation cause a significant change in RP11-2H8.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of RP11-2H8.2. Does this perturbation cause a significant change in RP11-2H8.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3594
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of TACC3 is measured. Determine whether TACC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of TACC3 is measured. Determine whether TACC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1866
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of CLINT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of CLINT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":437
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of PHF21A. Does perturbing DDOST lead to a significant change in PHF21A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of PHF21A. Does perturbing DDOST lead to a significant change in PHF21A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3851
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor NINJ2 expression. Decide whether this perturbation leads to a significant alteration in NINJ2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor NINJ2 expression. Decide whether this perturbation leads to a significant alteration in NINJ2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2148
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of LRIF1 is measured. Does this perturbation cause a significant change in LRIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of LRIF1 is measured. Does this perturbation cause a significant change in LRIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1450
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of LAMP2. Does perturbing HSD17B12 lead to a significant change in LAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of LAMP2. Does perturbing HSD17B12 lead to a significant change in LAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2771
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of S100A11. Does this perturbation cause a significant change in S100A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of S100A11. Does this perturbation cause a significant change in S100A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3254
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and ANKRD33 expression is measured. Determine whether ANKRD33 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and ANKRD33 expression is measured. Determine whether ANKRD33 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4189
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of UQCRB. Does this perturbation cause a significant change in UQCRB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of UQCRB. Does this perturbation cause a significant change in UQCRB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":704
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and PITPNB expression is quantified. Does this perturbation result in a significant change in PITPNB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and PITPNB expression is quantified. Does this perturbation result in a significant change in PITPNB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3732
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in IL18R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in IL18R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4205
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of DKFZP779L1853 is measured. Does this perturbation cause a significant change in DKFZP779L1853 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of DKFZP779L1853 is measured. Does this perturbation cause a significant change in DKFZP779L1853 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2380
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and NFAT5 expression is observed. Does this perturbation lead to a significant difference in NFAT5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and NFAT5 expression is observed. Does this perturbation lead to a significant difference in NFAT5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1813
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of HIST1H2BC is measured. Does this perturbation cause a significant change in HIST1H2BC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of HIST1H2BC is measured. Does this perturbation cause a significant change in HIST1H2BC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4770
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of DDX3X is measured. Does this perturbation cause a significant change in DDX3X expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of DDX3X is measured. Does this perturbation cause a significant change in DDX3X expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1080
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of RP11-573D15.9 is measured. Does this perturbation cause a significant change in RP11-573D15.9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of RP11-573D15.9 is measured. Does this perturbation cause a significant change in RP11-573D15.9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1290
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of RP11-471M2.3. Does perturbing SEC63 lead to a significant change in RP11-471M2.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of RP11-471M2.3. Does perturbing SEC63 lead to a significant change in RP11-471M2.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2591
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor ANKRD10 expression. Decide whether this perturbation leads to a significant alteration in ANKRD10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor ANKRD10 expression. Decide whether this perturbation leads to a significant alteration in ANKRD10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4358
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and C1GALT1 expression is measured. Determine whether C1GALT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and C1GALT1 expression is measured. Determine whether C1GALT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2009
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of PTPN11. Does this perturbation cause a significant change in PTPN11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of PTPN11. Does this perturbation cause a significant change in PTPN11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":504
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in SERPINF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in SERPINF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3955
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in RP1-274L7.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in RP1-274L7.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4075
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor SETX expression. Decide whether this perturbation leads to a significant alteration in SETX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor SETX expression. Decide whether this perturbation leads to a significant alteration in SETX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2478
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of MEX3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of MEX3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":677
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and QSER1 expression is measured. Determine whether QSER1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and QSER1 expression is measured. Determine whether QSER1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3009
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor RP11-789C1.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-789C1.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor RP11-789C1.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-789C1.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":948
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of TLK2 is measured. Does this perturbation cause a significant change in TLK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of TLK2 is measured. Does this perturbation cause a significant change in TLK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1990
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and SP100 expression is quantified. Does this perturbation result in a significant change in SP100 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and SP100 expression is quantified. Does this perturbation result in a significant change in SP100 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1142
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in HPCAL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in HPCAL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2975
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of RP11-157D23.2 is measured. Does this perturbation cause a significant change in RP11-157D23.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of RP11-157D23.2 is measured. Does this perturbation cause a significant change in RP11-157D23.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4420
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of P4HA2. Does this perturbation cause a significant change in P4HA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of P4HA2. Does this perturbation cause a significant change in P4HA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of PIK3R3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of PIK3R3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4027
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and ARHGAP11A expression is measured. Determine whether ARHGAP11A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and ARHGAP11A expression is measured. Determine whether ARHGAP11A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3729
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and AC079466.1 expression is measured. Determine whether AC079466.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and AC079466.1 expression is measured. Determine whether AC079466.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1449
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of PLB1 is measured. Does this perturbation cause a significant change in PLB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of PLB1 is measured. Does this perturbation cause a significant change in PLB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4950
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and ZFHX3 expression is quantified. Does this perturbation result in a significant change in ZFHX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":312
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of UBE2V1. Does perturbing SYVN1 lead to a significant change in UBE2V1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of UBE2V1. Does perturbing SYVN1 lead to a significant change in UBE2V1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1701
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of SERPINF2. Does this perturbation cause a significant change in SERPINF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of SERPINF2. Does this perturbation cause a significant change in SERPINF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3954
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of CTD-2587M2.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of CTD-2587M2.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1917
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and MLEC expression is observed. Does this perturbation lead to a significant difference in MLEC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and MLEC expression is observed. Does this perturbation lead to a significant difference in MLEC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3173
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and PSORS1C1 expression is measured. Determine whether PSORS1C1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and PSORS1C1 expression is measured. Determine whether PSORS1C1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2279
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and RP11-381O7.3 expression is quantified. Does this perturbation result in a significant change in RP11-381O7.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and RP11-381O7.3 expression is quantified. Does this perturbation result in a significant change in RP11-381O7.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1552
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of DNTTIP2 is measured. Determine whether DNTTIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of DNTTIP2 is measured. Determine whether DNTTIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":816
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of C10orf32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of C10orf32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3047
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RAI14. Does perturbing MARS lead to a significant change in RAI14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RAI14. Does perturbing MARS lead to a significant change in RAI14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2701
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and AC015987.2 expression is observed. Does this perturbation lead to a significant difference in AC015987.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and AC015987.2 expression is observed. Does this perturbation lead to a significant difference in AC015987.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2013
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of PPM1N is measured. Determine whether PPM1N shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of PPM1N is measured. Determine whether PPM1N shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3926
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of FYTTD1. Does this perturbation cause a significant change in FYTTD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of FYTTD1. Does this perturbation cause a significant change in FYTTD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2364
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ZXDA. Does perturbing SLC35B1 lead to a significant change in ZXDA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ZXDA. Does perturbing SLC35B1 lead to a significant change in ZXDA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3931
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor DYNC1H1 expression. Decide whether this perturbation leads to a significant alteration in DYNC1H1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor DYNC1H1 expression. Decide whether this perturbation leads to a significant alteration in DYNC1H1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3148
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of SSBP2. Does perturbing COPB1 lead to a significant change in SSBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of SSBP2. Does perturbing COPB1 lead to a significant change in SSBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4161
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and PHF3 expression is quantified. Does this perturbation result in a significant change in PHF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and PHF3 expression is quantified. Does this perturbation result in a significant change in PHF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of MYH7B. Does this perturbation cause a significant change in MYH7B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of MYH7B. Does this perturbation cause a significant change in MYH7B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":584
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and ATP6V1B2 expression is observed. Does this perturbation lead to a significant difference in ATP6V1B2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and ATP6V1B2 expression is observed. Does this perturbation lead to a significant difference in ATP6V1B2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1603
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ARHGAP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ARHGAP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3437
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and NAV1 expression is quantified. Does this perturbation result in a significant change in NAV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and NAV1 expression is quantified. Does this perturbation result in a significant change in NAV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4462
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and TLN1 expression is observed. Does this perturbation lead to a significant difference in TLN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and TLN1 expression is observed. Does this perturbation lead to a significant difference in TLN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1033
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor SHOX2 expression. Decide whether this perturbation leads to a significant alteration in SHOX2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor SHOX2 expression. Decide whether this perturbation leads to a significant alteration in SHOX2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":998
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of TRIM38. Does perturbing SRP72 lead to a significant change in TRIM38 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of TRIM38. Does perturbing SRP72 lead to a significant change in TRIM38 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3381
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of RP11-212I21.4. Does perturbing GNPNAT1 lead to a significant change in RP11-212I21.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of RP11-212I21.4. Does perturbing GNPNAT1 lead to a significant change in RP11-212I21.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2031
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and RSAD2 expression is observed. Does this perturbation lead to a significant difference in RSAD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and RSAD2 expression is observed. Does this perturbation lead to a significant difference in RSAD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1463
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of CTSV is measured. Does this perturbation cause a significant change in CTSV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of CTSV is measured. Does this perturbation cause a significant change in CTSV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2670
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of RNF8 is measured. Determine whether RNF8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of RNF8 is measured. Determine whether RNF8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3186
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of RNF139-AS1 is measured. Does this perturbation cause a significant change in RNF139-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of RNF139-AS1 is measured. Does this perturbation cause a significant change in RNF139-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2520
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor LRRC4B expression. Decide whether this perturbation leads to a significant alteration in LRRC4B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor LRRC4B expression. Decide whether this perturbation leads to a significant alteration in LRRC4B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2178
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of NPDC1 is measured. Determine whether NPDC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of NPDC1 is measured. Determine whether NPDC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1326
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2720
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of IL2RB is measured. Does this perturbation cause a significant change in IL2RB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of IL2RB is measured. Does this perturbation cause a significant change in IL2RB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4000
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of PCF11. Does perturbing YIPF5 lead to a significant change in PCF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of PCF11. Does perturbing YIPF5 lead to a significant change in PCF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":541
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and ACE expression is observed. Does this perturbation lead to a significant difference in ACE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and ACE expression is observed. Does this perturbation lead to a significant difference in ACE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2573
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor BRWD3 expression. Decide whether this perturbation leads to a significant alteration in BRWD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor BRWD3 expression. Decide whether this perturbation leads to a significant alteration in BRWD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":738
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in ZNF789 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in ZNF789 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3225
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor SLFNL1 expression. Decide whether this perturbation leads to a significant alteration in SLFNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor SLFNL1 expression. Decide whether this perturbation leads to a significant alteration in SLFNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":458
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor C10orf32 expression. Decide whether this perturbation leads to a significant alteration in C10orf32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor C10orf32 expression. Decide whether this perturbation leads to a significant alteration in C10orf32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3048
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in WARS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in WARS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4885
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and RGS20 expression is observed. Does this perturbation lead to a significant difference in RGS20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and RGS20 expression is observed. Does this perturbation lead to a significant difference in RGS20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4943
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of HMGCS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of HMGCS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":377
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of CD58. Does this perturbation cause a significant change in CD58 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of CD58. Does this perturbation cause a significant change in CD58 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2494
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and C9orf64 expression is measured. Determine whether C9orf64 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and C9orf64 expression is measured. Determine whether C9orf64 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3879
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of NXF1. Does perturbing SARS lead to a significant change in NXF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of NXF1. Does perturbing SARS lead to a significant change in NXF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3111
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor VIMP expression. Decide whether this perturbation leads to a significant alteration in VIMP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor VIMP expression. Decide whether this perturbation leads to a significant alteration in VIMP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4588
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of GDF11 is measured. Does this perturbation cause a significant change in GDF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of GDF11 is measured. Does this perturbation cause a significant change in GDF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":390
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and AC008074.3 expression is quantified. Does this perturbation result in a significant change in AC008074.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and AC008074.3 expression is quantified. Does this perturbation result in a significant change in AC008074.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1902
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor HIST1H1E expression. Decide whether this perturbation leads to a significant alteration in HIST1H1E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor HIST1H1E expression. Decide whether this perturbation leads to a significant alteration in HIST1H1E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1028
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of KDM1B is measured. Determine whether KDM1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of KDM1B is measured. Determine whether KDM1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1166
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of HIST1H2AM is measured. Does this perturbation cause a significant change in HIST1H2AM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of HIST1H2AM is measured. Does this perturbation cause a significant change in HIST1H2AM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2420
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and STC2 expression is quantified. Does this perturbation result in a significant change in STC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and STC2 expression is quantified. Does this perturbation result in a significant change in STC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":182
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor TROAP expression. Decide whether this perturbation leads to a significant alteration in TROAP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor TROAP expression. Decide whether this perturbation leads to a significant alteration in TROAP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3088
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and NAV2 expression is observed. Does this perturbation lead to a significant difference in NAV2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and NAV2 expression is observed. Does this perturbation lead to a significant difference in NAV2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4863
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of BACH2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of BACH2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3477
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of PDK2 is measured. Determine whether PDK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of PDK2 is measured. Determine whether PDK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2166
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2048
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and OR2T6 expression is measured. Determine whether OR2T6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and OR2T6 expression is measured. Determine whether OR2T6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1849
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of KCNH7 is measured. Determine whether KCNH7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of KCNH7 is measured. Determine whether KCNH7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1786
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of CD58 is measured. Does this perturbation cause a significant change in CD58 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of CD58 is measured. Does this perturbation cause a significant change in CD58 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2490
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of TFPI. Does this perturbation cause a significant change in TFPI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of TFPI. Does this perturbation cause a significant change in TFPI expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3914
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and AC018878.3 expression is quantified. Does this perturbation result in a significant change in AC018878.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and AC018878.3 expression is quantified. Does this perturbation result in a significant change in AC018878.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3282
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of ZEB2 is measured. Determine whether ZEB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of ZEB2 is measured. Determine whether ZEB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":966
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor HERPUD1 expression. Decide whether this perturbation leads to a significant alteration in HERPUD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor HERPUD1 expression. Decide whether this perturbation leads to a significant alteration in HERPUD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4438
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of KIAA1731. Does perturbing CARS lead to a significant change in KIAA1731 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of KIAA1731. Does perturbing CARS lead to a significant change in KIAA1731 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4891
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of RP11-435O5.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of RP11-435O5.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1197
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of EXOC3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of EXOC3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3357
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of WDR3 is measured. Does this perturbation cause a significant change in WDR3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of WDR3 is measured. Does this perturbation cause a significant change in WDR3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4560
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PHF19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PHF19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3065
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in WHSC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in WHSC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1485
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and IL13RA1 expression is observed. Does this perturbation lead to a significant difference in IL13RA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and IL13RA1 expression is observed. Does this perturbation lead to a significant difference in IL13RA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2353
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and ATP2A3 expression is observed. Does this perturbation lead to a significant difference in ATP2A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and ATP2A3 expression is observed. Does this perturbation lead to a significant difference in ATP2A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1833
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and KCNE3 expression is quantified. Does this perturbation result in a significant change in KCNE3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and KCNE3 expression is quantified. Does this perturbation result in a significant change in KCNE3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1012
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and KCNJ13 expression is quantified. Does this perturbation result in a significant change in KCNJ13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and KCNJ13 expression is quantified. Does this perturbation result in a significant change in KCNJ13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3652
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and USP37 expression is observed. Does this perturbation lead to a significant difference in USP37 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and USP37 expression is observed. Does this perturbation lead to a significant difference in USP37 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1733
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor NTRK1 expression. Decide whether this perturbation leads to a significant alteration in NTRK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor NTRK1 expression. Decide whether this perturbation leads to a significant alteration in NTRK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4038
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of RP11-445H22.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of RP11-445H22.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3817
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and LTB expression is quantified. Does this perturbation result in a significant change in LTB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and LTB expression is quantified. Does this perturbation result in a significant change in LTB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":322
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and RP11-434H6.6 expression is quantified. Does this perturbation result in a significant change in RP11-434H6.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and RP11-434H6.6 expression is quantified. Does this perturbation result in a significant change in RP11-434H6.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1892
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of S100A13. Does perturbing HSD17B12 lead to a significant change in S100A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of S100A13. Does perturbing HSD17B12 lead to a significant change in S100A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2781
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of RP11-146D12.2. Does this perturbation cause a significant change in RP11-146D12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of RP11-146D12.2. Does this perturbation cause a significant change in RP11-146D12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":474
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of CTSV. Does this perturbation cause a significant change in CTSV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of CTSV. Does this perturbation cause a significant change in CTSV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2674
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and KLK1 expression is quantified. Does this perturbation result in a significant change in KLK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and KLK1 expression is quantified. Does this perturbation result in a significant change in KLK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":202
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of PCK2. Does perturbing SEC61A1 lead to a significant change in PCK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of PCK2. Does perturbing SEC61A1 lead to a significant change in PCK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":331
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in GPR146 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in GPR146 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5085
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3503
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor KCNE3 expression. Decide whether this perturbation leads to a significant alteration in KCNE3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor KCNE3 expression. Decide whether this perturbation leads to a significant alteration in KCNE3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1018
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of KCTD1 is measured. Does this perturbation cause a significant change in KCTD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of KCTD1 is measured. Does this perturbation cause a significant change in KCTD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1370
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and RP11-423O2.5 expression is measured. Determine whether RP11-423O2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and RP11-423O2.5 expression is measured. Determine whether RP11-423O2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":309
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of HIST1H1E is measured. Determine whether HIST1H1E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of HIST1H1E is measured. Determine whether HIST1H1E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1026
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor GMEB1 expression. Decide whether this perturbation leads to a significant alteration in GMEB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor GMEB1 expression. Decide whether this perturbation leads to a significant alteration in GMEB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1208
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in PDRG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in PDRG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4155
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of C12orf44 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of C12orf44 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1537
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of RP11-227G15.8. Does perturbing TARS lead to a significant change in RP11-227G15.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of RP11-227G15.8. Does perturbing TARS lead to a significant change in RP11-227G15.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2931
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and RP11-322J23.1 expression is quantified. Does this perturbation result in a significant change in RP11-322J23.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and RP11-322J23.1 expression is quantified. Does this perturbation result in a significant change in RP11-322J23.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4722
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ARHGAP5 expression is observed. Does this perturbation lead to a significant difference in ARHGAP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ARHGAP5 expression is observed. Does this perturbation lead to a significant difference in ARHGAP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3433
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of ZNF341 is measured. Does this perturbation cause a significant change in ZNF341 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of ZNF341 is measured. Does this perturbation cause a significant change in ZNF341 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3770
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of PARP11. Does perturbing TIMM44 lead to a significant change in PARP11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of PARP11. Does perturbing TIMM44 lead to a significant change in PARP11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3701
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and S100A13 expression is observed. Does this perturbation lead to a significant difference in S100A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and S100A13 expression is observed. Does this perturbation lead to a significant difference in S100A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2783
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and IL2RB expression is measured. Determine whether IL2RB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and IL2RB expression is measured. Determine whether IL2RB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4009
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of RAD51AP1. Does perturbing SPCS2 lead to a significant change in RAD51AP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of RAD51AP1. Does perturbing SPCS2 lead to a significant change in RAD51AP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5141
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and NPAT expression is observed. Does this perturbation lead to a significant difference in NPAT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and NPAT expression is observed. Does this perturbation lead to a significant difference in NPAT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3323
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of ANPEP. Does this perturbation cause a significant change in ANPEP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of ANPEP. Does this perturbation cause a significant change in ANPEP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4794
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor PSORS1C1 expression. Decide whether this perturbation leads to a significant alteration in PSORS1C1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor PSORS1C1 expression. Decide whether this perturbation leads to a significant alteration in PSORS1C1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2278
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of VAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of VAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2907
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in ROCK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in ROCK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5155
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of NFE2L3 is measured. Determine whether NFE2L3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of NFE2L3 is measured. Determine whether NFE2L3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4826
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of CMTM6 is measured. Does this perturbation cause a significant change in CMTM6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of CMTM6 is measured. Does this perturbation cause a significant change in CMTM6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4910
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and HIST1H3D expression is measured. Determine whether HIST1H3D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and HIST1H3D expression is measured. Determine whether HIST1H3D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":919
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and TTC18 expression is measured. Determine whether TTC18 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and TTC18 expression is measured. Determine whether TTC18 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3699
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of STK17B. Does this perturbation cause a significant change in STK17B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of STK17B. Does this perturbation cause a significant change in STK17B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4854
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of DOCK8 is measured. Does this perturbation cause a significant change in DOCK8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of DOCK8 is measured. Does this perturbation cause a significant change in DOCK8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1560
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in FAM114A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in FAM114A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":715
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3966
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in CTC-308K20.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in CTC-308K20.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5135
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in RP11-227G15.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in RP11-227G15.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2935
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and REST expression is quantified. Does this perturbation result in a significant change in REST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and REST expression is quantified. Does this perturbation result in a significant change in REST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":792
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of ANPEP is measured. Does this perturbation cause a significant change in ANPEP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of ANPEP is measured. Does this perturbation cause a significant change in ANPEP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4790
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of H3F3B. Does this perturbation cause a significant change in H3F3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of H3F3B. Does this perturbation cause a significant change in H3F3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2324
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of AC079466.1. Does this perturbation cause a significant change in AC079466.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of AC079466.1. Does this perturbation cause a significant change in AC079466.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1444
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and LINC00938 expression is observed. Does this perturbation lead to a significant difference in LINC00938 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and LINC00938 expression is observed. Does this perturbation lead to a significant difference in LINC00938 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4103
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of RP11-181G12.2. Does this perturbation cause a significant change in RP11-181G12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of RP11-181G12.2. Does this perturbation cause a significant change in RP11-181G12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4374
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of PIK3IP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of PIK3IP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2867
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor OR2T6 expression. Decide whether this perturbation leads to a significant alteration in OR2T6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor OR2T6 expression. Decide whether this perturbation leads to a significant alteration in OR2T6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1848
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of TNFRSF10B. Does perturbing DDOST lead to a significant change in TNFRSF10B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of TNFRSF10B. Does perturbing DDOST lead to a significant change in TNFRSF10B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3861
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4573
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of TRPM4. Does this perturbation cause a significant change in TRPM4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of TRPM4. Does this perturbation cause a significant change in TRPM4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3844
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of GPR146 is measured. Determine whether GPR146 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of GPR146 is measured. Determine whether GPR146 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5086
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of SEPT5. Does this perturbation cause a significant change in SEPT5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of SEPT5. Does this perturbation cause a significant change in SEPT5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3544
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of RCBTB2. Does this perturbation cause a significant change in RCBTB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of RCBTB2. Does this perturbation cause a significant change in RCBTB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1334
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and TMEM87B expression is measured. Determine whether TMEM87B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and TMEM87B expression is measured. Determine whether TMEM87B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":829
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor RP11-24F11.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-24F11.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor RP11-24F11.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-24F11.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1498
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RGS20 is measured. Determine whether RGS20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RGS20 is measured. Determine whether RGS20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2716
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in RP11-666A20.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in RP11-666A20.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4235
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in ATXN7L3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in ATXN7L3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4935
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of DKFZP779L1853. Does perturbing HSPA9 lead to a significant change in DKFZP779L1853 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of DKFZP779L1853. Does perturbing HSPA9 lead to a significant change in DKFZP779L1853 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2381
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of SPINK5. Does this perturbation cause a significant change in SPINK5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of SPINK5. Does this perturbation cause a significant change in SPINK5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":414
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and KIAA1731 expression is observed. Does this perturbation lead to a significant difference in KIAA1731 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and KIAA1731 expression is observed. Does this perturbation lead to a significant difference in KIAA1731 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4893
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of VPS41 is measured. Determine whether VPS41 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of VPS41 is measured. Determine whether VPS41 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":636
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of TTC32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of TTC32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3217
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor NFE2 expression. Decide whether this perturbation leads to a significant alteration in NFE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor NFE2 expression. Decide whether this perturbation leads to a significant alteration in NFE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":218
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of PARP11 is measured. Determine whether PARP11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of PARP11 is measured. Determine whether PARP11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3706
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of TACC3. Does this perturbation cause a significant change in TACC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of TACC3. Does this perturbation cause a significant change in TACC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1864
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of DOK3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of DOK3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":267
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of RP11-363D14.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of RP11-363D14.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3057
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and RP11-360L9.8 expression is observed. Does this perturbation lead to a significant difference in RP11-360L9.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and RP11-360L9.8 expression is observed. Does this perturbation lead to a significant difference in RP11-360L9.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4293
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PHF19 expression. Decide whether this perturbation leads to a significant alteration in PHF19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PHF19 expression. Decide whether this perturbation leads to a significant alteration in PHF19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3068
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of KANSL1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of KANSL1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":647
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor AKAP11 expression. Decide whether this perturbation leads to a significant alteration in AKAP11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor AKAP11 expression. Decide whether this perturbation leads to a significant alteration in AKAP11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1928
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of RAD51AP1. Does this perturbation cause a significant change in RAD51AP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of RAD51AP1. Does this perturbation cause a significant change in RAD51AP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5144
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of GRN. Does this perturbation cause a significant change in GRN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of GRN. Does this perturbation cause a significant change in GRN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4334
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of ADAMTS10 is measured. Does this perturbation cause a significant change in ADAMTS10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of ADAMTS10 is measured. Does this perturbation cause a significant change in ADAMTS10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1070
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of ATF6 is measured. Does this perturbation cause a significant change in ATF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of ATF6 is measured. Does this perturbation cause a significant change in ATF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":850
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of PTGS1 is measured. Does this perturbation cause a significant change in PTGS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of PTGS1 is measured. Does this perturbation cause a significant change in PTGS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3480
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor OPTN expression. Decide whether this perturbation leads to a significant alteration in OPTN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor OPTN expression. Decide whether this perturbation leads to a significant alteration in OPTN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":558
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and TACC3 expression is quantified. Does this perturbation result in a significant change in TACC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and TACC3 expression is quantified. Does this perturbation result in a significant change in TACC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1862
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of RP11-15E18.1 is measured. Determine whether RP11-15E18.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of RP11-15E18.1 is measured. Determine whether RP11-15E18.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4056
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of NSD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of NSD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1347
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of RGS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of RGS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3127
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of KLF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of KLF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2297
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and RNF19A expression is quantified. Does this perturbation result in a significant change in RNF19A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and RNF19A expression is quantified. Does this perturbation result in a significant change in RNF19A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3762
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of GATA2. Does perturbing SPCS2 lead to a significant change in GATA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of GATA2. Does perturbing SPCS2 lead to a significant change in GATA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5111
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and CDCA3 expression is observed. Does this perturbation lead to a significant difference in CDCA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and CDCA3 expression is observed. Does this perturbation lead to a significant difference in CDCA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4113
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of RP11-838N2.4. Does this perturbation cause a significant change in RP11-838N2.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of RP11-838N2.4. Does this perturbation cause a significant change in RP11-838N2.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3034
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of C1GALT1. Does this perturbation cause a significant change in C1GALT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of C1GALT1. Does this perturbation cause a significant change in C1GALT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2004
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and ANKRD33 expression is observed. Does this perturbation lead to a significant difference in ANKRD33 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and ANKRD33 expression is observed. Does this perturbation lead to a significant difference in ANKRD33 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4183
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of ZNF678 is measured. Determine whether ZNF678 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of ZNF678 is measured. Determine whether ZNF678 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1366
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of UBE2V1 is measured. Does this perturbation cause a significant change in UBE2V1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of UBE2V1 is measured. Does this perturbation cause a significant change in UBE2V1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1700
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of CMTM6. Does this perturbation cause a significant change in CMTM6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of CMTM6. Does this perturbation cause a significant change in CMTM6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4914
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and NINJ2 expression is measured. Determine whether NINJ2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and NINJ2 expression is measured. Determine whether NINJ2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2149
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and RP11-666A20.4 expression is quantified. Does this perturbation result in a significant change in RP11-666A20.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and RP11-666A20.4 expression is quantified. Does this perturbation result in a significant change in RP11-666A20.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4232
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of RP11-3D4.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of RP11-3D4.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3647
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and TROAP expression is quantified. Does this perturbation result in a significant change in TROAP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and TROAP expression is quantified. Does this perturbation result in a significant change in TROAP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3082
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and BIRC5 expression is measured. Determine whether BIRC5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and BIRC5 expression is measured. Determine whether BIRC5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4509
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of RP11-423O2.5 is measured. Does this perturbation cause a significant change in RP11-423O2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of RP11-423O2.5 is measured. Does this perturbation cause a significant change in RP11-423O2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":300
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor PLA2G15 expression. Decide whether this perturbation leads to a significant alteration in PLA2G15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor PLA2G15 expression. Decide whether this perturbation leads to a significant alteration in PLA2G15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3838
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in NOXA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in NOXA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1415
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of NFE2. Does this perturbation cause a significant change in NFE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of NFE2. Does this perturbation cause a significant change in NFE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":214
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of PTBP3. Does perturbing SLMO2 lead to a significant change in PTBP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of PTBP3. Does perturbing SLMO2 lead to a significant change in PTBP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":661
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of ANXA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of ANXA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":747
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and FOXO6 expression is observed. Does this perturbation lead to a significant difference in FOXO6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and FOXO6 expression is observed. Does this perturbation lead to a significant difference in FOXO6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4123
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and SPCS2 expression is measured. Determine whether SPCS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and SPCS2 expression is measured. Determine whether SPCS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":699
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of RIMS3 is measured. Does this perturbation cause a significant change in RIMS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of RIMS3 is measured. Does this perturbation cause a significant change in RIMS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":160
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and EXOC3L2 expression is observed. Does this perturbation lead to a significant difference in EXOC3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and EXOC3L2 expression is observed. Does this perturbation lead to a significant difference in EXOC3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3353
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of COPB1 is measured. Does this perturbation cause a significant change in COPB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of COPB1 is measured. Does this perturbation cause a significant change in COPB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":800
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in POU2F2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in POU2F2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":655
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of MORC2-AS1. Does this perturbation cause a significant change in MORC2-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of MORC2-AS1. Does this perturbation cause a significant change in MORC2-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2554
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in DDX6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in DDX6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":525
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of OR2T6 is measured. Does this perturbation cause a significant change in OR2T6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of OR2T6 is measured. Does this perturbation cause a significant change in OR2T6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1840
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and DYNC1H1 expression is quantified. Does this perturbation result in a significant change in DYNC1H1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and DYNC1H1 expression is quantified. Does this perturbation result in a significant change in DYNC1H1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3142
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and SRP72 expression is observed. Does this perturbation lead to a significant difference in SRP72 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and SRP72 expression is observed. Does this perturbation lead to a significant difference in SRP72 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1233
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of PPP1R16B. Does this perturbation cause a significant change in PPP1R16B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of PPP1R16B. Does this perturbation cause a significant change in PPP1R16B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4484
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of ANKRD11 is measured. Does this perturbation cause a significant change in ANKRD11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of ANKRD11 is measured. Does this perturbation cause a significant change in ANKRD11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4690
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in SIGLEC6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in SIGLEC6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3345
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of QSER1 is measured. Does this perturbation cause a significant change in QSER1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of QSER1 is measured. Does this perturbation cause a significant change in QSER1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4680
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of SHOX2. Does this perturbation cause a significant change in SHOX2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of SHOX2. Does this perturbation cause a significant change in SHOX2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":994
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in SRP72 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in SRP72 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1235
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and TIPARP expression is quantified. Does this perturbation result in a significant change in TIPARP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and TIPARP expression is quantified. Does this perturbation result in a significant change in TIPARP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3612
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and F2RL2 expression is observed. Does this perturbation lead to a significant difference in F2RL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and F2RL2 expression is observed. Does this perturbation lead to a significant difference in F2RL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2333
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor RP11-430H10.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-430H10.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor RP11-430H10.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-430H10.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5028
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of KIAA0922. Does perturbing PTDSS1 lead to a significant change in KIAA0922 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of KIAA0922. Does perturbing PTDSS1 lead to a significant change in KIAA0922 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3741
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of C6orf48. Does perturbing CREB1 lead to a significant change in C6orf48 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of C6orf48. Does perturbing CREB1 lead to a significant change in C6orf48 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and SPAST expression is quantified. Does this perturbation result in a significant change in SPAST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and SPAST expression is quantified. Does this perturbation result in a significant change in SPAST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2842
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of CTC-550B14.7. Does this perturbation cause a significant change in CTC-550B14.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of CTC-550B14.7. Does this perturbation cause a significant change in CTC-550B14.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4554
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of RSL24D1. Does this perturbation cause a significant change in RSL24D1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of RSL24D1. Does this perturbation cause a significant change in RSL24D1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":874
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and ERP29 expression is quantified. Does this perturbation result in a significant change in ERP29 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and ERP29 expression is quantified. Does this perturbation result in a significant change in ERP29 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5072
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and MS4A6E expression is observed. Does this perturbation lead to a significant difference in MS4A6E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and MS4A6E expression is observed. Does this perturbation lead to a significant difference in MS4A6E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":343
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of DDX3X. Does perturbing SOCS1 lead to a significant change in DDX3X expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of DDX3X. Does perturbing SOCS1 lead to a significant change in DDX3X expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1081
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in LTB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in LTB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4705
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of TMEM87B is measured. Determine whether TMEM87B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of TMEM87B is measured. Determine whether TMEM87B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":826
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ARHGAP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ARHGAP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3435
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor QSER1 expression. Decide whether this perturbation leads to a significant alteration in QSER1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor QSER1 expression. Decide whether this perturbation leads to a significant alteration in QSER1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4688
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in TLN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in TLN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1035
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and TMOD3 expression is measured. Determine whether TMOD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and TMOD3 expression is measured. Determine whether TMOD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1519
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of PIK3IP1 is measured. Does this perturbation cause a significant change in PIK3IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of PIK3IP1 is measured. Does this perturbation cause a significant change in PIK3IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2860
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":840
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of ATP5EP2. Does this perturbation cause a significant change in ATP5EP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of ATP5EP2. Does this perturbation cause a significant change in ATP5EP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2954
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of SERPINF2 is measured. Does this perturbation cause a significant change in SERPINF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of SERPINF2 is measured. Does this perturbation cause a significant change in SERPINF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3950
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of H3F3B. Does perturbing TELO2 lead to a significant change in H3F3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of H3F3B. Does perturbing TELO2 lead to a significant change in H3F3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2321
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of TAP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of TAP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4717
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and C10orf32 expression is observed. Does this perturbation lead to a significant difference in C10orf32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and C10orf32 expression is observed. Does this perturbation lead to a significant difference in C10orf32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3043
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of CTC-308K20.1 is measured. Does this perturbation cause a significant change in CTC-308K20.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of CTC-308K20.1 is measured. Does this perturbation cause a significant change in CTC-308K20.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5130
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and HIST1H1E expression is quantified. Does this perturbation result in a significant change in HIST1H1E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and HIST1H1E expression is quantified. Does this perturbation result in a significant change in HIST1H1E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1022
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of SRP72 is measured. Determine whether SRP72 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of SRP72 is measured. Determine whether SRP72 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1236
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and FAM212A expression is quantified. Does this perturbation result in a significant change in FAM212A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and FAM212A expression is quantified. Does this perturbation result in a significant change in FAM212A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2232
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of HAGH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of HAGH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2637
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and NFE2L3 expression is observed. Does this perturbation lead to a significant difference in NFE2L3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and NFE2L3 expression is observed. Does this perturbation lead to a significant difference in NFE2L3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1583
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and GSN expression is observed. Does this perturbation lead to a significant difference in GSN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and GSN expression is observed. Does this perturbation lead to a significant difference in GSN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3203
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor C17orf64 expression. Decide whether this perturbation leads to a significant alteration in C17orf64 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor C17orf64 expression. Decide whether this perturbation leads to a significant alteration in C17orf64 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3718
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of PPP1R16B is measured. Determine whether PPP1R16B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of PPP1R16B is measured. Determine whether PPP1R16B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":596
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and CYP17A1-AS1 expression is observed. Does this perturbation lead to a significant difference in CYP17A1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and CYP17A1-AS1 expression is observed. Does this perturbation lead to a significant difference in CYP17A1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1243
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of HLA-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of HLA-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":767
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of CASP4 is measured. Determine whether CASP4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of CASP4 is measured. Determine whether CASP4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in EPS15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in EPS15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4845
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of RP11-254F7.4 is measured. Determine whether RP11-254F7.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of RP11-254F7.4 is measured. Determine whether RP11-254F7.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2396
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of GDF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of GDF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":397
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor SIGLEC6 expression. Decide whether this perturbation leads to a significant alteration in SIGLEC6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor SIGLEC6 expression. Decide whether this perturbation leads to a significant alteration in SIGLEC6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3348
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in ZP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in ZP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2545
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RAI14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RAI14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2707
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and NOXA1 expression is quantified. Does this perturbation result in a significant change in NOXA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and NOXA1 expression is quantified. Does this perturbation result in a significant change in NOXA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1412
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of PBDC1 is measured. Does this perturbation cause a significant change in PBDC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of PBDC1 is measured. Does this perturbation cause a significant change in PBDC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":600
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of LRIF1 is measured. Determine whether LRIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of LRIF1 is measured. Determine whether LRIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1456
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of CHST12 is measured. Does this perturbation cause a significant change in CHST12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of CHST12 is measured. Does this perturbation cause a significant change in CHST12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3460
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor HRK expression. Decide whether this perturbation leads to a significant alteration in HRK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor HRK expression. Decide whether this perturbation leads to a significant alteration in HRK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1048
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of P4HB. Does perturbing COPZ1 lead to a significant change in P4HB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of P4HB. Does perturbing COPZ1 lead to a significant change in P4HB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4611
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and SPEN expression is quantified. Does this perturbation result in a significant change in SPEN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and SPEN expression is quantified. Does this perturbation result in a significant change in SPEN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1572
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of C12orf44. Does perturbing SEL1L lead to a significant change in C12orf44 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of C12orf44. Does perturbing SEL1L lead to a significant change in C12orf44 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1531
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of PTAR1 is measured. Does this perturbation cause a significant change in PTAR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of PTAR1 is measured. Does this perturbation cause a significant change in PTAR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2100
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and C6orf120 expression is observed. Does this perturbation lead to a significant difference in C6orf120 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and C6orf120 expression is observed. Does this perturbation lead to a significant difference in C6orf120 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2263
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor ZFHX3 expression. Decide whether this perturbation leads to a significant alteration in ZFHX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1138
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of KCTD19. Does this perturbation cause a significant change in KCTD19 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of KCTD19. Does this perturbation cause a significant change in KCTD19 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2684
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and EGLN3 expression is quantified. Does this perturbation result in a significant change in EGLN3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and EGLN3 expression is quantified. Does this perturbation result in a significant change in EGLN3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3312
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of PELO is measured. Does this perturbation cause a significant change in PELO expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of PELO is measured. Does this perturbation cause a significant change in PELO expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2110
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of AP000688.8 is measured. Determine whether AP000688.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of AP000688.8 is measured. Determine whether AP000688.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3336
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in KCNE3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in KCNE3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1015
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of WDR72 is measured. Does this perturbation cause a significant change in WDR72 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of WDR72 is measured. Does this perturbation cause a significant change in WDR72 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4130
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor CTCFL expression. Decide whether this perturbation leads to a significant alteration in CTCFL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor CTCFL expression. Decide whether this perturbation leads to a significant alteration in CTCFL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2608
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor ZNF789 expression. Decide whether this perturbation leads to a significant alteration in ZNF789 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor ZNF789 expression. Decide whether this perturbation leads to a significant alteration in ZNF789 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3228
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of NAV1 is measured. Determine whether NAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of NAV1 is measured. Determine whether NAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4466
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of CTBS. Does perturbing PPWD1 lead to a significant change in CTBS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of CTBS. Does perturbing PPWD1 lead to a significant change in CTBS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4441
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ARHGAP6 expression is quantified. Does this perturbation result in a significant change in ARHGAP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ARHGAP6 expression is quantified. Does this perturbation result in a significant change in ARHGAP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3422
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of HERC2. Does perturbing DARS lead to a significant change in HERC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of HERC2. Does perturbing DARS lead to a significant change in HERC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":951
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of PPP1R16B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of PPP1R16B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4487
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and HMGCS1 expression is measured. Determine whether HMGCS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and HMGCS1 expression is measured. Determine whether HMGCS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":379
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of DDX6. Does this perturbation cause a significant change in DDX6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of DDX6. Does this perturbation cause a significant change in DDX6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":524
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and NOX5 expression is measured. Determine whether NOX5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and NOX5 expression is measured. Determine whether NOX5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3419
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of KCNJ13. Does perturbing EIF2S1 lead to a significant change in KCNJ13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of KCNJ13. Does perturbing EIF2S1 lead to a significant change in KCNJ13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3651
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and RP11-16E12.1 expression is quantified. Does this perturbation result in a significant change in RP11-16E12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and RP11-16E12.1 expression is quantified. Does this perturbation result in a significant change in RP11-16E12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3232
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and CEBPG expression is observed. Does this perturbation lead to a significant difference in CEBPG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and CEBPG expression is observed. Does this perturbation lead to a significant difference in CEBPG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and NCKAP1L expression is quantified. Does this perturbation result in a significant change in NCKAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and NCKAP1L expression is quantified. Does this perturbation result in a significant change in NCKAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":442
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and ACSM3 expression is observed. Does this perturbation lead to a significant difference in ACSM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and ACSM3 expression is observed. Does this perturbation lead to a significant difference in ACSM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2213
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of POU2F2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of POU2F2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":657
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of CASP8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of CASP8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":227
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor ZNF678 expression. Decide whether this perturbation leads to a significant alteration in ZNF678 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor ZNF678 expression. Decide whether this perturbation leads to a significant alteration in ZNF678 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1368
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of PTGS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of PTGS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3487
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of DKFZP779L1853 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of DKFZP779L1853 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2387
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and GUSB expression is quantified. Does this perturbation result in a significant change in GUSB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and GUSB expression is quantified. Does this perturbation result in a significant change in GUSB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1932
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of NRIP1 is measured. Does this perturbation cause a significant change in NRIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of NRIP1 is measured. Does this perturbation cause a significant change in NRIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3620
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor RP11-360L9.8 expression. Decide whether this perturbation leads to a significant alteration in RP11-360L9.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor RP11-360L9.8 expression. Decide whether this perturbation leads to a significant alteration in RP11-360L9.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4298
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and SPEN expression is quantified. Does this perturbation result in a significant change in SPEN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and SPEN expression is quantified. Does this perturbation result in a significant change in SPEN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4082
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of VIMP. Does this perturbation cause a significant change in VIMP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of VIMP. Does this perturbation cause a significant change in VIMP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":974
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and NOXA1 expression is observed. Does this perturbation lead to a significant difference in NOXA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and NOXA1 expression is observed. Does this perturbation lead to a significant difference in NOXA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1413
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2042
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of PPP1R16B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of PPP1R16B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":597
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of RNF8. Does this perturbation cause a significant change in RNF8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of RNF8. Does this perturbation cause a significant change in RNF8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3184
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor RP11-2H8.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-2H8.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor RP11-2H8.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-2H8.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3598
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of TMEM60. Does this perturbation cause a significant change in TMEM60 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of TMEM60. Does this perturbation cause a significant change in TMEM60 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4974
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and CASP8 expression is quantified. Does this perturbation result in a significant change in CASP8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and CASP8 expression is quantified. Does this perturbation result in a significant change in CASP8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":222
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and IL2RB expression is measured. Determine whether IL2RB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and IL2RB expression is measured. Determine whether IL2RB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3609
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of RP11-328J2.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of RP11-328J2.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1097
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and GDF11 expression is measured. Determine whether GDF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and GDF11 expression is measured. Determine whether GDF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":399
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and DKFZP779L1853 expression is observed. Does this perturbation lead to a significant difference in DKFZP779L1853 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and DKFZP779L1853 expression is observed. Does this perturbation lead to a significant difference in DKFZP779L1853 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2383
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of ARHGAP30 is measured. Does this perturbation cause a significant change in ARHGAP30 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of ARHGAP30 is measured. Does this perturbation cause a significant change in ARHGAP30 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1470
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and RGS20 expression is quantified. Does this perturbation result in a significant change in RGS20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and RGS20 expression is quantified. Does this perturbation result in a significant change in RGS20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4942
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of GATA3 is measured. Does this perturbation cause a significant change in GATA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of GATA3 is measured. Does this perturbation cause a significant change in GATA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":880
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and SNHG10 expression is measured. Determine whether SNHG10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and SNHG10 expression is measured. Determine whether SNHG10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1889
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in ANKRD33 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in ANKRD33 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4185
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2099
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of GCKR is measured. Does this perturbation cause a significant change in GCKR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of GCKR is measured. Does this perturbation cause a significant change in GCKR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4300
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in OPTN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in OPTN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":555
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor TMEM60 expression. Decide whether this perturbation leads to a significant alteration in TMEM60 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor TMEM60 expression. Decide whether this perturbation leads to a significant alteration in TMEM60 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4978
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and S100A13 expression is quantified. Does this perturbation result in a significant change in S100A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and S100A13 expression is quantified. Does this perturbation result in a significant change in S100A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2782
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of RP11-322J23.1. Does perturbing SEC61G lead to a significant change in RP11-322J23.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of RP11-322J23.1. Does perturbing SEC61G lead to a significant change in RP11-322J23.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4721
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and KLK1 expression is measured. Determine whether KLK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and KLK1 expression is measured. Determine whether KLK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":209
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of UBE3A. Does perturbing DDRGK1 lead to a significant change in UBE3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of UBE3A. Does perturbing DDRGK1 lead to a significant change in UBE3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1221
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of ANXA4. Does perturbing DAD1 lead to a significant change in ANXA4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of ANXA4. Does perturbing DAD1 lead to a significant change in ANXA4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":741
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of NFE2L3. Does perturbing XRN1 lead to a significant change in NFE2L3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of NFE2L3. Does perturbing XRN1 lead to a significant change in NFE2L3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4821
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in AC104532.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in AC104532.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2985
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RAI14 expression is quantified. Does this perturbation result in a significant change in RAI14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RAI14 expression is quantified. Does this perturbation result in a significant change in RAI14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2702
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of RSAD2. Does perturbing MRGBP lead to a significant change in RSAD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of RSAD2. Does perturbing MRGBP lead to a significant change in RSAD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1461
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in SETX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in SETX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2475
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of MANF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of MANF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2417
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of RP11-181G12.2. Does perturbing SRPRB lead to a significant change in RP11-181G12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of RP11-181G12.2. Does perturbing SRPRB lead to a significant change in RP11-181G12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4371
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RIOK3 is measured. Does this perturbation cause a significant change in RIOK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RIOK3 is measured. Does this perturbation cause a significant change in RIOK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and LBX1 expression is measured. Determine whether LBX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and LBX1 expression is measured. Determine whether LBX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1599
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in PAK1IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in PAK1IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4255
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and CTSV expression is measured. Determine whether CTSV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and CTSV expression is measured. Determine whether CTSV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2679
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of JUND. Does perturbing DAD1 lead to a significant change in JUND expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of JUND. Does perturbing DAD1 lead to a significant change in JUND expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":771
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4570
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of HAGH is measured. Does this perturbation cause a significant change in HAGH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of HAGH is measured. Does this perturbation cause a significant change in HAGH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2630
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor COPB1 expression. Decide whether this perturbation leads to a significant alteration in COPB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor COPB1 expression. Decide whether this perturbation leads to a significant alteration in COPB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":808
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and IL2RB expression is quantified. Does this perturbation result in a significant change in IL2RB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and IL2RB expression is quantified. Does this perturbation result in a significant change in IL2RB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4002
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of TXNIP. Does perturbing SLC39A7 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of TXNIP. Does perturbing SLC39A7 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2121
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and LTBP1 expression is measured. Determine whether LTBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and LTBP1 expression is measured. Determine whether LTBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1809
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of AC012594.1. Does perturbing ATP5B lead to a significant change in AC012594.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of AC012594.1. Does perturbing ATP5B lead to a significant change in AC012594.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1671
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of GUSB is measured. Does this perturbation cause a significant change in GUSB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of GUSB is measured. Does this perturbation cause a significant change in GUSB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1930
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of SLFNL1 is measured. Does this perturbation cause a significant change in SLFNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of SLFNL1 is measured. Does this perturbation cause a significant change in SLFNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":450
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of CD46 is measured. Does this perturbation cause a significant change in CD46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of CD46 is measured. Does this perturbation cause a significant change in CD46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4210
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of KCNQ1OT1 is measured. Does this perturbation cause a significant change in KCNQ1OT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of KCNQ1OT1 is measured. Does this perturbation cause a significant change in KCNQ1OT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4620
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of C12orf44 is measured. Determine whether C12orf44 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of C12orf44 is measured. Determine whether C12orf44 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1536
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of GDF11. Does perturbing EIF2B4 lead to a significant change in GDF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of GDF11. Does perturbing EIF2B4 lead to a significant change in GDF11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":391
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and VIMP expression is measured. Determine whether VIMP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and VIMP expression is measured. Determine whether VIMP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":979
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of RIMS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of RIMS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":167
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RP11-685N10.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RP11-685N10.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2755
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and RP11-90P5.2 expression is quantified. Does this perturbation result in a significant change in RP11-90P5.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and RP11-90P5.2 expression is quantified. Does this perturbation result in a significant change in RP11-90P5.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":402
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of CCDC69. Does this perturbation cause a significant change in CCDC69 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of CCDC69. Does this perturbation cause a significant change in CCDC69 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3444
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in CENPC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in CENPC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4455
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RIOK3 is measured. Determine whether RIOK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RIOK3 is measured. Determine whether RIOK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor PKDCC expression. Decide whether this perturbation leads to a significant alteration in PKDCC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor PKDCC expression. Decide whether this perturbation leads to a significant alteration in PKDCC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1798
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of RP3-465N24.6 is measured. Determine whether RP3-465N24.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of RP3-465N24.6 is measured. Determine whether RP3-465N24.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3586
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of MTPN. Does this perturbation cause a significant change in MTPN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of MTPN. Does this perturbation cause a significant change in MTPN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4734
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of RP11-16E12.1. Does perturbing TTI1 lead to a significant change in RP11-16E12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of RP11-16E12.1. Does perturbing TTI1 lead to a significant change in RP11-16E12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3231
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of PSMC1 is measured. Does this perturbation cause a significant change in PSMC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of PSMC1 is measured. Does this perturbation cause a significant change in PSMC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2820
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of ARHGAP30. Does this perturbation cause a significant change in ARHGAP30 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of ARHGAP30. Does this perturbation cause a significant change in ARHGAP30 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1474
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of HPCAL1 is measured. Determine whether HPCAL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of HPCAL1 is measured. Determine whether HPCAL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2976
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of PHF3 is measured. Determine whether PHF3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of PHF3 is measured. Determine whether PHF3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and HIST1H2AM expression is quantified. Does this perturbation result in a significant change in HIST1H2AM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and HIST1H2AM expression is quantified. Does this perturbation result in a significant change in HIST1H2AM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":382
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of IL18R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of IL18R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":357
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and SAMM50 expression is quantified. Does this perturbation result in a significant change in SAMM50 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and SAMM50 expression is quantified. Does this perturbation result in a significant change in SAMM50 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":622
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and P4HB expression is observed. Does this perturbation lead to a significant difference in P4HB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and P4HB expression is observed. Does this perturbation lead to a significant difference in P4HB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4613
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of UHRF1BP1L is measured. Determine whether UHRF1BP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of UHRF1BP1L is measured. Determine whether UHRF1BP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":246
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and GUSB expression is quantified. Does this perturbation result in a significant change in GUSB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and GUSB expression is quantified. Does this perturbation result in a significant change in GUSB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1402
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of NOX5. Does this perturbation cause a significant change in NOX5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of NOX5. Does this perturbation cause a significant change in NOX5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3414
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and RILPL2 expression is quantified. Does this perturbation result in a significant change in RILPL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and RILPL2 expression is quantified. Does this perturbation result in a significant change in RILPL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4142
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of OPTN is measured. Does this perturbation cause a significant change in OPTN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of OPTN is measured. Does this perturbation cause a significant change in OPTN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":550
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4756
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of PCK2. Does this perturbation cause a significant change in PCK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of PCK2. Does this perturbation cause a significant change in PCK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":334
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of RP11-863K10.7. Does this perturbation cause a significant change in RP11-863K10.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of RP11-863K10.7. Does this perturbation cause a significant change in RP11-863K10.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":934
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and MBNL1 expression is measured. Determine whether MBNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and MBNL1 expression is measured. Determine whether MBNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4819
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of ACE is measured. Determine whether ACE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of ACE is measured. Determine whether ACE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2576
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of RP11-61E11.1 is measured. Determine whether RP11-61E11.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of RP11-61E11.1 is measured. Determine whether RP11-61E11.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1426
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and ZNF341 expression is measured. Determine whether ZNF341 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and ZNF341 expression is measured. Determine whether ZNF341 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3779
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and HERPUD1 expression is measured. Determine whether HERPUD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and HERPUD1 expression is measured. Determine whether HERPUD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4439
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of NUF2 is measured. Determine whether NUF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of NUF2 is measured. Determine whether NUF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1396
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor FAM212A expression. Decide whether this perturbation leads to a significant alteration in FAM212A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor FAM212A expression. Decide whether this perturbation leads to a significant alteration in FAM212A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2238
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and CTD-2001C12.1 expression is measured. Determine whether CTD-2001C12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and CTD-2001C12.1 expression is measured. Determine whether CTD-2001C12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":579
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of LPAR5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of LPAR5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of PTAR1. Does this perturbation cause a significant change in PTAR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of PTAR1. Does this perturbation cause a significant change in PTAR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2104
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of RP13-216E22.4. Does perturbing MRPL39 lead to a significant change in RP13-216E22.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of RP13-216E22.4. Does perturbing MRPL39 lead to a significant change in RP13-216E22.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2431
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of DDX6 is measured. Determine whether DDX6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of DDX6 is measured. Determine whether DDX6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":526
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor EPS15 expression. Decide whether this perturbation leads to a significant alteration in EPS15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor EPS15 expression. Decide whether this perturbation leads to a significant alteration in EPS15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4848
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and SNRNP25 expression is quantified. Does this perturbation result in a significant change in SNRNP25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and SNRNP25 expression is quantified. Does this perturbation result in a significant change in SNRNP25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2152
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and ZNF292 expression is quantified. Does this perturbation result in a significant change in ZNF292 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and ZNF292 expression is quantified. Does this perturbation result in a significant change in ZNF292 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1502
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in YTHDF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in YTHDF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4925
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of TROAP is measured. Does this perturbation cause a significant change in TROAP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of TROAP is measured. Does this perturbation cause a significant change in TROAP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3080
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of CTD-2001C12.1. Does perturbing YIPF5 lead to a significant change in CTD-2001C12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of CTD-2001C12.1. Does perturbing YIPF5 lead to a significant change in CTD-2001C12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":571
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and CLDN11 expression is observed. Does this perturbation lead to a significant difference in CLDN11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and CLDN11 expression is observed. Does this perturbation lead to a significant difference in CLDN11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4543
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in TRIM24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in TRIM24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3195
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of KHDC1L. Does this perturbation cause a significant change in KHDC1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of KHDC1L. Does this perturbation cause a significant change in KHDC1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1064
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of CTD-2521M24.9 is measured. Determine whether CTD-2521M24.9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of CTD-2521M24.9 is measured. Determine whether CTD-2521M24.9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2996
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of C12orf44 is measured. Does this perturbation cause a significant change in C12orf44 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of C12orf44 is measured. Does this perturbation cause a significant change in C12orf44 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1530
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and DSC2 expression is observed. Does this perturbation lead to a significant difference in DSC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and DSC2 expression is observed. Does this perturbation lead to a significant difference in DSC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4093
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of KCNH7. Does this perturbation cause a significant change in KCNH7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of KCNH7. Does this perturbation cause a significant change in KCNH7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1784
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of RP11-499F3.2 is measured. Determine whether RP11-499F3.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of RP11-499F3.2 is measured. Determine whether RP11-499F3.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2886
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PIF1 expression is measured. Determine whether PIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PIF1 expression is measured. Determine whether PIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3079
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ZFP36L2 expression is observed. Does this perturbation lead to a significant difference in ZFP36L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ZFP36L2 expression is observed. Does this perturbation lead to a significant difference in ZFP36L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3453
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of SIGLEC6. Does perturbing PSMD4 lead to a significant change in SIGLEC6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of SIGLEC6. Does perturbing PSMD4 lead to a significant change in SIGLEC6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3341
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of KCTD19. Does perturbing MANF lead to a significant change in KCTD19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of KCTD19. Does perturbing MANF lead to a significant change in KCTD19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2681
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and QSER1 expression is measured. Determine whether QSER1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and QSER1 expression is measured. Determine whether QSER1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4689
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ARHGAP5. Does this perturbation cause a significant change in ARHGAP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ARHGAP5. Does this perturbation cause a significant change in ARHGAP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3434
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and TAP1 expression is measured. Determine whether TAP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and TAP1 expression is measured. Determine whether TAP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4719
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and RP3-465N24.6 expression is observed. Does this perturbation lead to a significant difference in RP3-465N24.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and RP3-465N24.6 expression is observed. Does this perturbation lead to a significant difference in RP3-465N24.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3583
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and KIAA1731 expression is quantified. Does this perturbation result in a significant change in KIAA1731 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and KIAA1731 expression is quantified. Does this perturbation result in a significant change in KIAA1731 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4892
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of ZNF429 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of ZNF429 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and NFE2L3 expression is measured. Determine whether NFE2L3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and NFE2L3 expression is measured. Determine whether NFE2L3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4829
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2727
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of HIST1H1D is measured. Determine whether HIST1H1D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of HIST1H1D is measured. Determine whether HIST1H1D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4346
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and C17orf64 expression is observed. Does this perturbation lead to a significant difference in C17orf64 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and C17orf64 expression is observed. Does this perturbation lead to a significant difference in C17orf64 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3713
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of AC018878.3. Does perturbing HSPA5 lead to a significant change in AC018878.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of AC018878.3. Does perturbing HSPA5 lead to a significant change in AC018878.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3281
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor RP11-471M2.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-471M2.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor RP11-471M2.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-471M2.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2598
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in CTD-2587M2.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in CTD-2587M2.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1915
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor KIAA1432 expression. Decide whether this perturbation leads to a significant alteration in KIAA1432 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor KIAA1432 expression. Decide whether this perturbation leads to a significant alteration in KIAA1432 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3758
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of ZC3H7A is measured. Determine whether ZC3H7A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of ZC3H7A is measured. Determine whether ZC3H7A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3676
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PHF19 expression is observed. Does this perturbation lead to a significant difference in PHF19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PHF19 expression is observed. Does this perturbation lead to a significant difference in PHF19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3063
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and ZNF678 expression is quantified. Does this perturbation result in a significant change in ZNF678 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and ZNF678 expression is quantified. Does this perturbation result in a significant change in ZNF678 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1362
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor PTPRC expression. Decide whether this perturbation leads to a significant alteration in PTPRC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor PTPRC expression. Decide whether this perturbation leads to a significant alteration in PTPRC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":238
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of RNF19A. Does this perturbation cause a significant change in RNF19A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of RNF19A. Does this perturbation cause a significant change in RNF19A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3764
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of QSER1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of QSER1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5007
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and PSORS1C1 expression is observed. Does this perturbation lead to a significant difference in PSORS1C1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and PSORS1C1 expression is observed. Does this perturbation lead to a significant difference in PSORS1C1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2273
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of DUT. Does this perturbation cause a significant change in DUT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of DUT. Does this perturbation cause a significant change in DUT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":274
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and TMEM60 expression is observed. Does this perturbation lead to a significant difference in TMEM60 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and TMEM60 expression is observed. Does this perturbation lead to a significant difference in TMEM60 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4973
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and RP11-666A20.4 expression is measured. Determine whether RP11-666A20.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and RP11-666A20.4 expression is measured. Determine whether RP11-666A20.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4239
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of TMEM60. Does perturbing SCYL1 lead to a significant change in TMEM60 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of TMEM60. Does perturbing SCYL1 lead to a significant change in TMEM60 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3511
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor ARHGAP6 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor ARHGAP6 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1758
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor TGOLN2 expression. Decide whether this perturbation leads to a significant alteration in TGOLN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor TGOLN2 expression. Decide whether this perturbation leads to a significant alteration in TGOLN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5098
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of TNFRSF10B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of TNFRSF10B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3867
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of RP11-863K10.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of RP11-863K10.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":937
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and RP11-181G12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-181G12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and RP11-181G12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-181G12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4373
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in DUSP21 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in DUSP21 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2745
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of TMEM87B. Does this perturbation cause a significant change in TMEM87B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of TMEM87B. Does this perturbation cause a significant change in TMEM87B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":824
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of SPINK5. Does perturbing EIF2B4 lead to a significant change in SPINK5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of SPINK5. Does perturbing EIF2B4 lead to a significant change in SPINK5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":411
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of RP11-132A1.4. Does this perturbation cause a significant change in RP11-132A1.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of RP11-132A1.4. Does this perturbation cause a significant change in RP11-132A1.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":724
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor BAMBI expression. Decide whether this perturbation leads to a significant alteration in BAMBI expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor BAMBI expression. Decide whether this perturbation leads to a significant alteration in BAMBI expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1178
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and MEX3B expression is measured. Determine whether MEX3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and MEX3B expression is measured. Determine whether MEX3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":679
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of ZEB2 is measured. Does this perturbation cause a significant change in ZEB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of ZEB2 is measured. Does this perturbation cause a significant change in ZEB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":960
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of ZNF280B. Does this perturbation cause a significant change in ZNF280B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of ZNF280B. Does this perturbation cause a significant change in ZNF280B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1104
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of CCRL2. Does this perturbation cause a significant change in CCRL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of CCRL2. Does this perturbation cause a significant change in CCRL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3554
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of MANF is measured. Does this perturbation cause a significant change in MANF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of MANF is measured. Does this perturbation cause a significant change in MANF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2410
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor RP11-157D23.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-157D23.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor RP11-157D23.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-157D23.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4428
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor IL32 expression. Decide whether this perturbation leads to a significant alteration in IL32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor IL32 expression. Decide whether this perturbation leads to a significant alteration in IL32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":568
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of DDIT4. Does perturbing GMPPB lead to a significant change in DDIT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of DDIT4. Does perturbing GMPPB lead to a significant change in DDIT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1821
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and ZNF789 expression is quantified. Does this perturbation result in a significant change in ZNF789 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and ZNF789 expression is quantified. Does this perturbation result in a significant change in ZNF789 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3222
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of CTSV. Does perturbing MANF lead to a significant change in CTSV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of CTSV. Does perturbing MANF lead to a significant change in CTSV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2671
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor ESCO1 expression. Decide whether this perturbation leads to a significant alteration in ESCO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor ESCO1 expression. Decide whether this perturbation leads to a significant alteration in ESCO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":868
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1692
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and NPDC1 expression is observed. Does this perturbation lead to a significant difference in NPDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and NPDC1 expression is observed. Does this perturbation lead to a significant difference in NPDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1323
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of RP11-119J18.1 is measured. Determine whether RP11-119J18.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of RP11-119J18.1 is measured. Determine whether RP11-119J18.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2446
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of AC008074.3. Does this perturbation cause a significant change in AC008074.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of AC008074.3. Does this perturbation cause a significant change in AC008074.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1904
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and EXO1 expression is quantified. Does this perturbation result in a significant change in EXO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and EXO1 expression is quantified. Does this perturbation result in a significant change in EXO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2832
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor SKIL expression. Decide whether this perturbation leads to a significant alteration in SKIL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor SKIL expression. Decide whether this perturbation leads to a significant alteration in SKIL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2948
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor LTN1 expression. Decide whether this perturbation leads to a significant alteration in LTN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor LTN1 expression. Decide whether this perturbation leads to a significant alteration in LTN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3788
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of ZNF280B. Does perturbing QARS lead to a significant change in ZNF280B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of ZNF280B. Does perturbing QARS lead to a significant change in ZNF280B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1281
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of IDH3A. Does perturbing MANF lead to a significant change in IDH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of IDH3A. Does perturbing MANF lead to a significant change in IDH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2641
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of ARHGAP30 is measured. Determine whether ARHGAP30 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of ARHGAP30 is measured. Determine whether ARHGAP30 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1476
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2530
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and PPP4R2 expression is quantified. Does this perturbation result in a significant change in PPP4R2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and PPP4R2 expression is quantified. Does this perturbation result in a significant change in PPP4R2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2372
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of P4HA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of P4HA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2407
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of LIMS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of LIMS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3377
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of CTD-2020K17.1 is measured. Determine whether CTD-2020K17.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of CTD-2020K17.1 is measured. Determine whether CTD-2020K17.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4196
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of IDS is measured. Determine whether IDS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of IDS is measured. Determine whether IDS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4276
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and C1GALT1 expression is observed. Does this perturbation lead to a significant difference in C1GALT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and C1GALT1 expression is observed. Does this perturbation lead to a significant difference in C1GALT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2003
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of RGS3 is measured. Determine whether RGS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of RGS3 is measured. Determine whether RGS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2876
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of ARSA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of ARSA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":687
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of RP11-15E18.1 is measured. Does this perturbation cause a significant change in RP11-15E18.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of RP11-15E18.1 is measured. Does this perturbation cause a significant change in RP11-15E18.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4050
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and EBI3 expression is quantified. Does this perturbation result in a significant change in EBI3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and EBI3 expression is quantified. Does this perturbation result in a significant change in EBI3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1652
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of IL18R1 is measured. Determine whether IL18R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of IL18R1 is measured. Determine whether IL18R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4206
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and PTPN11 expression is quantified. Does this perturbation result in a significant change in PTPN11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and PTPN11 expression is quantified. Does this perturbation result in a significant change in PTPN11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":502
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and CTSV expression is quantified. Does this perturbation result in a significant change in CTSV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and CTSV expression is quantified. Does this perturbation result in a significant change in CTSV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2672
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of RP11-38P22.2 is measured. Does this perturbation cause a significant change in RP11-38P22.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of RP11-38P22.2 is measured. Does this perturbation cause a significant change in RP11-38P22.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1050
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor LPAR5 expression. Decide whether this perturbation leads to a significant alteration in LPAR5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor LPAR5 expression. Decide whether this perturbation leads to a significant alteration in LPAR5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and AC104532.4 expression is quantified. Does this perturbation result in a significant change in AC104532.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and AC104532.4 expression is quantified. Does this perturbation result in a significant change in AC104532.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2982
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in MANF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in MANF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2075
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and ARHGAP6 expression is quantified. Does this perturbation result in a significant change in ARHGAP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and ARHGAP6 expression is quantified. Does this perturbation result in a significant change in ARHGAP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1752
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of ARHGAP11A is measured. Determine whether ARHGAP11A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of ARHGAP11A is measured. Determine whether ARHGAP11A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3726
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor TIPARP expression. Decide whether this perturbation leads to a significant alteration in TIPARP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor TIPARP expression. Decide whether this perturbation leads to a significant alteration in TIPARP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3618
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of ARHGDIB is measured. Does this perturbation cause a significant change in ARHGDIB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of ARHGDIB is measured. Does this perturbation cause a significant change in ARHGDIB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1960
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and RP1-274L7.1 expression is measured. Determine whether RP1-274L7.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and RP1-274L7.1 expression is measured. Determine whether RP1-274L7.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4079
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and RP11-304M2.5 expression is quantified. Does this perturbation result in a significant change in RP11-304M2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and RP11-304M2.5 expression is quantified. Does this perturbation result in a significant change in RP11-304M2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4532
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1697
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of WARS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of WARS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4887
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and ANPEP expression is measured. Determine whether ANPEP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and ANPEP expression is measured. Determine whether ANPEP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4799
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2737
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and TRAPPC10 expression is observed. Does this perturbation lead to a significant difference in TRAPPC10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and TRAPPC10 expression is observed. Does this perturbation lead to a significant difference in TRAPPC10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1853
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of RGS3 is measured. Does this perturbation cause a significant change in RGS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of RGS3 is measured. Does this perturbation cause a significant change in RGS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2870
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of SLC27A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of SLC27A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3687
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in LDLR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in LDLR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":495
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of AC012594.1 is measured. Determine whether AC012594.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of AC012594.1 is measured. Determine whether AC012594.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1676
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor SOBP expression. Decide whether this perturbation leads to a significant alteration in SOBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor SOBP expression. Decide whether this perturbation leads to a significant alteration in SOBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3638
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and CCRL2 expression is observed. Does this perturbation lead to a significant difference in CCRL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and CCRL2 expression is observed. Does this perturbation lead to a significant difference in CCRL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3553
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of EP400. Does perturbing TIMM44 lead to a significant change in EP400 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of EP400. Does perturbing TIMM44 lead to a significant change in EP400 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3661
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2127
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and C17orf64 expression is measured. Determine whether C17orf64 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and C17orf64 expression is measured. Determine whether C17orf64 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3719
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of NXF1 is measured. Does this perturbation cause a significant change in NXF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of NXF1 is measured. Does this perturbation cause a significant change in NXF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3110
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4287
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and CENPF expression is measured. Determine whether CENPF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and CENPF expression is measured. Determine whether CENPF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4069
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of PLB1. Does this perturbation cause a significant change in PLB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of PLB1. Does this perturbation cause a significant change in PLB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4954
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of TLK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of TLK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1997
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in TROAP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in TROAP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3085
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and C9orf64 expression is quantified. Does this perturbation result in a significant change in C9orf64 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and C9orf64 expression is quantified. Does this perturbation result in a significant change in C9orf64 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3872
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and TFPI expression is observed. Does this perturbation lead to a significant difference in TFPI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and TFPI expression is observed. Does this perturbation lead to a significant difference in TFPI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3913
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2303
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and H3F3B expression is measured. Determine whether H3F3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and H3F3B expression is measured. Determine whether H3F3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2329
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and TSC22D4 expression is measured. Determine whether TSC22D4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and TSC22D4 expression is measured. Determine whether TSC22D4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3279
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of CLCA1. Does perturbing TELO2 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of CLCA1. Does perturbing TELO2 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2301
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of PDE9A. Does this perturbation cause a significant change in PDE9A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of PDE9A. Does this perturbation cause a significant change in PDE9A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":194
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of RP11-573D15.2. Does this perturbation cause a significant change in RP11-573D15.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of RP11-573D15.2. Does this perturbation cause a significant change in RP11-573D15.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3884
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of RP11-227G15.8. Does this perturbation cause a significant change in RP11-227G15.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of RP11-227G15.8. Does this perturbation cause a significant change in RP11-227G15.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2934
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of AC005540.3. Does this perturbation cause a significant change in AC005540.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of AC005540.3. Does this perturbation cause a significant change in AC005540.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4414
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and ATXN7L3B expression is measured. Determine whether ATXN7L3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and ATXN7L3B expression is measured. Determine whether ATXN7L3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4939
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor NUF2 expression. Decide whether this perturbation leads to a significant alteration in NUF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor NUF2 expression. Decide whether this perturbation leads to a significant alteration in NUF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1398
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of NOX5. Does perturbing SRP72 lead to a significant change in NOX5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of NOX5. Does perturbing SRP72 lead to a significant change in NOX5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3411
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and TSNAXIP1 expression is observed. Does this perturbation lead to a significant difference in TSNAXIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and TSNAXIP1 expression is observed. Does this perturbation lead to a significant difference in TSNAXIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":753
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of JARID2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of JARID2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1217
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of ITGB2 is measured. Determine whether ITGB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of ITGB2 is measured. Determine whether ITGB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1306
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and CTC-308K20.1 expression is observed. Does this perturbation lead to a significant difference in CTC-308K20.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and CTC-308K20.1 expression is observed. Does this perturbation lead to a significant difference in CTC-308K20.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5133
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and STARD9 expression is measured. Determine whether STARD9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and STARD9 expression is measured. Determine whether STARD9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4609
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and RP11-132A1.4 expression is observed. Does this perturbation lead to a significant difference in RP11-132A1.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and RP11-132A1.4 expression is observed. Does this perturbation lead to a significant difference in RP11-132A1.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":723
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and RSAD2 expression is quantified. Does this perturbation result in a significant change in RSAD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and RSAD2 expression is quantified. Does this perturbation result in a significant change in RSAD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4402
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of HERPUD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of HERPUD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4437
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of QSER1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of QSER1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4687
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of EIF3A. Does this perturbation cause a significant change in EIF3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of EIF3A. Does this perturbation cause a significant change in EIF3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4804
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2040
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of AC015987.1. Does perturbing NEDD8 lead to a significant change in AC015987.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of AC015987.1. Does perturbing NEDD8 lead to a significant change in AC015987.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2251
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of PLA2G15. Does this perturbation cause a significant change in PLA2G15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of PLA2G15. Does this perturbation cause a significant change in PLA2G15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3834
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and CDKN2C expression is measured. Determine whether CDKN2C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and CDKN2C expression is measured. Determine whether CDKN2C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2819
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor EBI3 expression. Decide whether this perturbation leads to a significant alteration in EBI3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor EBI3 expression. Decide whether this perturbation leads to a significant alteration in EBI3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1658
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of BIRC5 is measured. Determine whether BIRC5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of BIRC5 is measured. Determine whether BIRC5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4506
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of TIPARP is measured. Determine whether TIPARP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of TIPARP is measured. Determine whether TIPARP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3616
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of C10orf32. Does perturbing EIF2B2 lead to a significant change in C10orf32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of C10orf32. Does perturbing EIF2B2 lead to a significant change in C10orf32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3041
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor KCNJ13 expression. Decide whether this perturbation leads to a significant alteration in KCNJ13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor KCNJ13 expression. Decide whether this perturbation leads to a significant alteration in KCNJ13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3658
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and IL32 expression is quantified. Does this perturbation result in a significant change in IL32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and IL32 expression is quantified. Does this perturbation result in a significant change in IL32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":562
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of FYTTD1. Does perturbing HSPA9 lead to a significant change in FYTTD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of FYTTD1. Does perturbing HSPA9 lead to a significant change in FYTTD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2361
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and DKFZP779L1853 expression is quantified. Does this perturbation result in a significant change in DKFZP779L1853 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and DKFZP779L1853 expression is quantified. Does this perturbation result in a significant change in DKFZP779L1853 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2382
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and IL2RB expression is quantified. Does this perturbation result in a significant change in IL2RB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and IL2RB expression is quantified. Does this perturbation result in a significant change in IL2RB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3602
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and SLC25A35 expression is observed. Does this perturbation lead to a significant difference in SLC25A35 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and SLC25A35 expression is observed. Does this perturbation lead to a significant difference in SLC25A35 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3153
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and CENPC expression is observed. Does this perturbation lead to a significant difference in CENPC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and CENPC expression is observed. Does this perturbation lead to a significant difference in CENPC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2183
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor WHSC1 expression. Decide whether this perturbation leads to a significant alteration in WHSC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor WHSC1 expression. Decide whether this perturbation leads to a significant alteration in WHSC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1488
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor TSPAN33 expression. Decide whether this perturbation leads to a significant alteration in TSPAN33 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor TSPAN33 expression. Decide whether this perturbation leads to a significant alteration in TSPAN33 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3528
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of KLK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of KLK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":207
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and VIM-AS1 expression is observed. Does this perturbation lead to a significant difference in VIM-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and VIM-AS1 expression is observed. Does this perturbation lead to a significant difference in VIM-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":483
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and PTBP3 expression is observed. Does this perturbation lead to a significant difference in PTBP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and PTBP3 expression is observed. Does this perturbation lead to a significant difference in PTBP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":663
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of RGS20. Does this perturbation cause a significant change in RGS20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of RGS20. Does this perturbation cause a significant change in RGS20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3124
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of LINC01137 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of LINC01137 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4667
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in RP11-322J23.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in RP11-322J23.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4725
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of MBNL1 is measured. Determine whether MBNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of MBNL1 is measured. Determine whether MBNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4816
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of MEX3B is measured. Does this perturbation cause a significant change in MEX3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of MEX3B is measured. Does this perturbation cause a significant change in MEX3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":670
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of NFE2 is measured. Determine whether NFE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of NFE2 is measured. Determine whether NFE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":216
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and SMCO1 expression is measured. Determine whether SMCO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and SMCO1 expression is measured. Determine whether SMCO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4499
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor CDRT4 expression. Decide whether this perturbation leads to a significant alteration in CDRT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor CDRT4 expression. Decide whether this perturbation leads to a significant alteration in CDRT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":288
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and H3F3B expression is quantified. Does this perturbation result in a significant change in H3F3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and H3F3B expression is quantified. Does this perturbation result in a significant change in H3F3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2322
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of TET1 is measured. Does this perturbation cause a significant change in TET1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of TET1 is measured. Does this perturbation cause a significant change in TET1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":130
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and S100A11 expression is quantified. Does this perturbation result in a significant change in S100A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and S100A11 expression is quantified. Does this perturbation result in a significant change in S100A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3252
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of HIST1H2AM. Does perturbing EIF2B4 lead to a significant change in HIST1H2AM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of HIST1H2AM. Does perturbing EIF2B4 lead to a significant change in HIST1H2AM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":381
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of SLFNL1 is measured. Determine whether SLFNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of SLFNL1 is measured. Determine whether SLFNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":456
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of GLG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of GLG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1947
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of MBNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of MBNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4817
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor MLEC expression. Decide whether this perturbation leads to a significant alteration in MLEC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor MLEC expression. Decide whether this perturbation leads to a significant alteration in MLEC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3178
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ARHGAP6 expression is observed. Does this perturbation lead to a significant difference in ARHGAP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ARHGAP6 expression is observed. Does this perturbation lead to a significant difference in ARHGAP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3423
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of ZP3. Does this perturbation cause a significant change in ZP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of ZP3. Does this perturbation cause a significant change in ZP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2544
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of HM13 is measured. Does this perturbation cause a significant change in HM13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of HM13 is measured. Does this perturbation cause a significant change in HM13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4510
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of ATP11B. Does perturbing OST4 lead to a significant change in ATP11B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of ATP11B. Does perturbing OST4 lead to a significant change in ATP11B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":291
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and RP11-430H10.1 expression is quantified. Does this perturbation result in a significant change in RP11-430H10.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and RP11-430H10.1 expression is quantified. Does this perturbation result in a significant change in RP11-430H10.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5022
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RP11-141B14.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-141B14.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RP11-141B14.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-141B14.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and SETX expression is measured. Determine whether SETX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and SETX expression is measured. Determine whether SETX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3369
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and AMOTL1 expression is quantified. Does this perturbation result in a significant change in AMOTL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and AMOTL1 expression is quantified. Does this perturbation result in a significant change in AMOTL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2242
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor CST7 expression. Decide whether this perturbation leads to a significant alteration in CST7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor CST7 expression. Decide whether this perturbation leads to a significant alteration in CST7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2208
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of KLK1 is measured. Determine whether KLK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of KLK1 is measured. Determine whether KLK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":206
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of TNFRSF10B is measured. Determine whether TNFRSF10B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of TNFRSF10B is measured. Determine whether TNFRSF10B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2286
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor PIK3R1 expression. Decide whether this perturbation leads to a significant alteration in PIK3R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor PIK3R1 expression. Decide whether this perturbation leads to a significant alteration in PIK3R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5108
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and RASGRP2 expression is measured. Determine whether RASGRP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and RASGRP2 expression is measured. Determine whether RASGRP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4269
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of PDE9A. Does perturbing DDIT3 lead to a significant change in PDE9A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of PDE9A. Does perturbing DDIT3 lead to a significant change in PDE9A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":191
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of GUSB is measured. Determine whether GUSB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of GUSB is measured. Determine whether GUSB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1406
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of SLC26A1 is measured. Does this perturbation cause a significant change in SLC26A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of SLC26A1 is measured. Does this perturbation cause a significant change in SLC26A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2190
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of RASGRP2. Does perturbing AARS lead to a significant change in RASGRP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of RASGRP2. Does perturbing AARS lead to a significant change in RASGRP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4261
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of IL13RA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of IL13RA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2357
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor GUSB expression. Decide whether this perturbation leads to a significant alteration in GUSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor GUSB expression. Decide whether this perturbation leads to a significant alteration in GUSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1938
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and ROCK1 expression is observed. Does this perturbation lead to a significant difference in ROCK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and ROCK1 expression is observed. Does this perturbation lead to a significant difference in ROCK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5153
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of TNFRSF10B is measured. Determine whether TNFRSF10B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of TNFRSF10B is measured. Determine whether TNFRSF10B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3866
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and DOCK8 expression is observed. Does this perturbation lead to a significant difference in DOCK8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and DOCK8 expression is observed. Does this perturbation lead to a significant difference in DOCK8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1563
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and RSAD2 expression is observed. Does this perturbation lead to a significant difference in RSAD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and RSAD2 expression is observed. Does this perturbation lead to a significant difference in RSAD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4403
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of LTN1. Does this perturbation cause a significant change in LTN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of LTN1. Does this perturbation cause a significant change in LTN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3134
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of TMEM60. Does perturbing TMED2 lead to a significant change in TMEM60 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of TMEM60. Does perturbing TMED2 lead to a significant change in TMEM60 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4971
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of ROCK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of ROCK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5157
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of CTD-2521M24.9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of CTD-2521M24.9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2997
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor MTPN expression. Decide whether this perturbation leads to a significant alteration in MTPN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor MTPN expression. Decide whether this perturbation leads to a significant alteration in MTPN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4738
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and KIAA1586 expression is observed. Does this perturbation lead to a significant difference in KIAA1586 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and KIAA1586 expression is observed. Does this perturbation lead to a significant difference in KIAA1586 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4653
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and GATA2 expression is measured. Determine whether GATA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and GATA2 expression is measured. Determine whether GATA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5119
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of MTPN is measured. Does this perturbation cause a significant change in MTPN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of MTPN is measured. Does this perturbation cause a significant change in MTPN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4730
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in GPRC5C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in GPRC5C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2225
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of P4HB is measured. Does this perturbation cause a significant change in P4HB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of P4HB is measured. Does this perturbation cause a significant change in P4HB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4610
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in S100A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in S100A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3255
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and TNFRSF10B expression is measured. Determine whether TNFRSF10B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and TNFRSF10B expression is measured. Determine whether TNFRSF10B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2289
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of LINC01137 is measured. Determine whether LINC01137 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of LINC01137 is measured. Determine whether LINC01137 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4666
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of IL8 is measured. Determine whether IL8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of IL8 is measured. Determine whether IL8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1256
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of RP11-390B4.5 is measured. Determine whether RP11-390B4.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of RP11-390B4.5 is measured. Determine whether RP11-390B4.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4836
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of EGLN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of EGLN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3317
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of RNF19A is measured. Determine whether RNF19A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of RNF19A is measured. Determine whether RNF19A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3766
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in SMCO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in SMCO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4495
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of RP11-181G12.2 is measured. Determine whether RP11-181G12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of RP11-181G12.2 is measured. Determine whether RP11-181G12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4376
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor PDE9A expression. Decide whether this perturbation leads to a significant alteration in PDE9A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor PDE9A expression. Decide whether this perturbation leads to a significant alteration in PDE9A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":198
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor AMOTL1 expression. Decide whether this perturbation leads to a significant alteration in AMOTL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor AMOTL1 expression. Decide whether this perturbation leads to a significant alteration in AMOTL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2248
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and JARID2 expression is quantified. Does this perturbation result in a significant change in JARID2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and JARID2 expression is quantified. Does this perturbation result in a significant change in JARID2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1212
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in CENPC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in CENPC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2185
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of VIM-AS1 is measured. Does this perturbation cause a significant change in VIM-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of VIM-AS1 is measured. Does this perturbation cause a significant change in VIM-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":480
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of IL18R1. Does perturbing CHERP lead to a significant change in IL18R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of IL18R1. Does perturbing CHERP lead to a significant change in IL18R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4201
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of USP34. Does perturbing SRPRB lead to a significant change in USP34 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of USP34. Does perturbing SRPRB lead to a significant change in USP34 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4361
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of SSBP2 is measured. Determine whether SSBP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of SSBP2 is measured. Determine whether SSBP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4166
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of PDE3B is measured. Does this perturbation cause a significant change in PDE3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of PDE3B is measured. Does this perturbation cause a significant change in PDE3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4780
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of RP11-3D4.3. Does this perturbation cause a significant change in RP11-3D4.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of RP11-3D4.3. Does this perturbation cause a significant change in RP11-3D4.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3644
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and CTSV expression is observed. Does this perturbation lead to a significant difference in CTSV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and CTSV expression is observed. Does this perturbation lead to a significant difference in CTSV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2673
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of SEC23IP. Does perturbing TMED10 lead to a significant change in SEC23IP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of SEC23IP. Does perturbing TMED10 lead to a significant change in SEC23IP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3971
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of RP11-471M2.3. Does this perturbation cause a significant change in RP11-471M2.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of RP11-471M2.3. Does this perturbation cause a significant change in RP11-471M2.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2594
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of PDE3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of PDE3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4787
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of RP11-132A1.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of RP11-132A1.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":727
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RIOK3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RIOK3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in RP3-465N24.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in RP3-465N24.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3585
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of GLG1 is measured. Determine whether GLG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of GLG1 is measured. Determine whether GLG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1946
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and CRNDE expression is observed. Does this perturbation lead to a significant difference in CRNDE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and CRNDE expression is observed. Does this perturbation lead to a significant difference in CRNDE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1973
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of CST7. Does perturbing DERL2 lead to a significant change in CST7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of CST7. Does perturbing DERL2 lead to a significant change in CST7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2201
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and ZNF678 expression is measured. Determine whether ZNF678 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and ZNF678 expression is measured. Determine whether ZNF678 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1369
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of CTC-550B14.7. Does perturbing DHDDS lead to a significant change in CTC-550B14.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of CTC-550B14.7. Does perturbing DHDDS lead to a significant change in CTC-550B14.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4551
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of NPAT is measured. Does this perturbation cause a significant change in NPAT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of NPAT is measured. Does this perturbation cause a significant change in NPAT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3320
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and BAMBI expression is observed. Does this perturbation lead to a significant difference in BAMBI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and BAMBI expression is observed. Does this perturbation lead to a significant difference in BAMBI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1173
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of ERP29. Does this perturbation cause a significant change in ERP29 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of ERP29. Does this perturbation cause a significant change in ERP29 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5074
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and WDR3 expression is measured. Determine whether WDR3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and WDR3 expression is measured. Determine whether WDR3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4569
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of TMEM87B. Does perturbing TIMM23 lead to a significant change in TMEM87B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of TMEM87B. Does perturbing TIMM23 lead to a significant change in TMEM87B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":821
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and YTHDF2 expression is quantified. Does this perturbation result in a significant change in YTHDF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and YTHDF2 expression is quantified. Does this perturbation result in a significant change in YTHDF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4922
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and RP11-138C9.1 expression is observed. Does this perturbation lead to a significant difference in RP11-138C9.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and RP11-138C9.1 expression is observed. Does this perturbation lead to a significant difference in RP11-138C9.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":833
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3500
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of MANF. Does perturbing MRPL39 lead to a significant change in MANF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of MANF. Does perturbing MRPL39 lead to a significant change in MANF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2411
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in LINC01137 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in LINC01137 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4665
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor MANF expression. Decide whether this perturbation leads to a significant alteration in MANF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor MANF expression. Decide whether this perturbation leads to a significant alteration in MANF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2078
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor DUSP21 expression. Decide whether this perturbation leads to a significant alteration in DUSP21 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor DUSP21 expression. Decide whether this perturbation leads to a significant alteration in DUSP21 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2748
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of PDRG1 is measured. Does this perturbation cause a significant change in PDRG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of PDRG1 is measured. Does this perturbation cause a significant change in PDRG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4150
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of DYNC1H1 is measured. Does this perturbation cause a significant change in DYNC1H1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of DYNC1H1 is measured. Does this perturbation cause a significant change in DYNC1H1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3140
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of TLK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of TLK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4767
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RIOK3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RIOK3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4280
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of RGS3. Does perturbing SEC61B lead to a significant change in RGS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of RGS3. Does perturbing SEC61B lead to a significant change in RGS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2871
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in QSER1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in QSER1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3005
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of RP11-334C17.5. Does this perturbation cause a significant change in RP11-334C17.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of RP11-334C17.5. Does this perturbation cause a significant change in RP11-334C17.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1004
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of GALNT7 is measured. Does this perturbation cause a significant change in GALNT7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of GALNT7 is measured. Does this perturbation cause a significant change in GALNT7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4380
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of USP34 is measured. Does this perturbation cause a significant change in USP34 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of USP34 is measured. Does this perturbation cause a significant change in USP34 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4360
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of NOSTRIN is measured. Does this perturbation cause a significant change in NOSTRIN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of NOSTRIN is measured. Does this perturbation cause a significant change in NOSTRIN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4320
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of SERPINH1 is measured. Determine whether SERPINH1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of SERPINH1 is measured. Determine whether SERPINH1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1646
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of BIRC5. Does perturbing DHDDS lead to a significant change in BIRC5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of BIRC5. Does perturbing DHDDS lead to a significant change in BIRC5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4501
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of IL18R1. Does this perturbation cause a significant change in IL18R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of IL18R1. Does this perturbation cause a significant change in IL18R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":354
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RP11-685N10.1. Does perturbing MARS lead to a significant change in RP11-685N10.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RP11-685N10.1. Does perturbing MARS lead to a significant change in RP11-685N10.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2751
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and CDRT4 expression is quantified. Does this perturbation result in a significant change in CDRT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and CDRT4 expression is quantified. Does this perturbation result in a significant change in CDRT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":282
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of HRK. Does this perturbation cause a significant change in HRK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of HRK. Does this perturbation cause a significant change in HRK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1044
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and DDX3X expression is observed. Does this perturbation lead to a significant difference in DDX3X expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and DDX3X expression is observed. Does this perturbation lead to a significant difference in DDX3X expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1083
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in RSAD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in RSAD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1465
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and DOCK8 expression is quantified. Does this perturbation result in a significant change in DOCK8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and DOCK8 expression is quantified. Does this perturbation result in a significant change in DOCK8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1562
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of AC008074.3. Does perturbing CAD lead to a significant change in AC008074.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of AC008074.3. Does perturbing CAD lead to a significant change in AC008074.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1901
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and THBS1 expression is quantified. Does this perturbation result in a significant change in THBS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and THBS1 expression is quantified. Does this perturbation result in a significant change in THBS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5012
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in ATP2A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in ATP2A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1835
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of CD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of CD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":427
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of AC007038.7 is measured. Does this perturbation cause a significant change in AC007038.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of AC007038.7 is measured. Does this perturbation cause a significant change in AC007038.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2920
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of CST7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of CST7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2207
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of AC007038.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of AC007038.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2927
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of AC079466.1 is measured. Determine whether AC079466.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of AC079466.1 is measured. Determine whether AC079466.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1446
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and RNF19A expression is measured. Determine whether RNF19A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and RNF19A expression is measured. Determine whether RNF19A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3769
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of DOK3 is measured. Determine whether DOK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of DOK3 is measured. Determine whether DOK3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":266
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and RDH10 expression is measured. Determine whether RDH10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and RDH10 expression is measured. Determine whether RDH10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":149
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in RP11-423O2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in RP11-423O2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":305
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of LINC00862 is measured. Does this perturbation cause a significant change in LINC00862 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of LINC00862 is measured. Does this perturbation cause a significant change in LINC00862 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4590
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in ITGB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in ITGB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1305
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of GPRC5C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of GPRC5C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2227
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of RSL24D1 is measured. Determine whether RSL24D1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of RSL24D1 is measured. Determine whether RSL24D1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":876
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of CLDN11 is measured. Does this perturbation cause a significant change in CLDN11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of CLDN11 is measured. Does this perturbation cause a significant change in CLDN11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2610
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":844
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of MORF4L2 is measured. Determine whether MORF4L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of MORF4L2 is measured. Determine whether MORF4L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2626
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of SNRNP25. Does this perturbation cause a significant change in SNRNP25 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of SNRNP25. Does this perturbation cause a significant change in SNRNP25 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2154
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and PSMC1 expression is quantified. Does this perturbation result in a significant change in PSMC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and PSMC1 expression is quantified. Does this perturbation result in a significant change in PSMC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2822
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and LINC00657 expression is measured. Determine whether LINC00657 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and LINC00657 expression is measured. Determine whether LINC00657 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":259
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and RP11-360L9.8 expression is observed. Does this perturbation lead to a significant difference in RP11-360L9.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and RP11-360L9.8 expression is observed. Does this perturbation lead to a significant difference in RP11-360L9.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2793
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in RP11-3D4.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in RP11-3D4.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3645
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in KCTD19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in KCTD19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2685
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of AC012594.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of AC012594.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1677
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of ATP2A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of ATP2A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1837
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and F2RL2 expression is quantified. Does this perturbation result in a significant change in F2RL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and F2RL2 expression is quantified. Does this perturbation result in a significant change in F2RL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2332
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor PPP1R16B expression. Decide whether this perturbation leads to a significant alteration in PPP1R16B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor PPP1R16B expression. Decide whether this perturbation leads to a significant alteration in PPP1R16B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":598
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and PIK3R1 expression is quantified. Does this perturbation result in a significant change in PIK3R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and PIK3R1 expression is quantified. Does this perturbation result in a significant change in PIK3R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5102
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and MYH7B expression is measured. Determine whether MYH7B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and MYH7B expression is measured. Determine whether MYH7B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":589
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and CTD-2020K17.1 expression is measured. Determine whether CTD-2020K17.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and CTD-2020K17.1 expression is measured. Determine whether CTD-2020K17.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4199
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ARHGAP5. Does perturbing KCTD16 lead to a significant change in ARHGAP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ARHGAP5. Does perturbing KCTD16 lead to a significant change in ARHGAP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3431
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of JARID2 is measured. Determine whether JARID2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of JARID2 is measured. Determine whether JARID2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1216
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of PITPNB. Does perturbing PTDSS1 lead to a significant change in PITPNB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of PITPNB. Does perturbing PTDSS1 lead to a significant change in PITPNB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3731
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of RP11-119J18.1 is measured. Does this perturbation cause a significant change in RP11-119J18.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of RP11-119J18.1 is measured. Does this perturbation cause a significant change in RP11-119J18.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2440
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor VPS41 expression. Decide whether this perturbation leads to a significant alteration in VPS41 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor VPS41 expression. Decide whether this perturbation leads to a significant alteration in VPS41 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":638
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and CTD-2267D19.3 expression is measured. Determine whether CTD-2267D19.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and CTD-2267D19.3 expression is measured. Determine whether CTD-2267D19.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1549
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and IL8 expression is quantified. Does this perturbation result in a significant change in IL8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and IL8 expression is quantified. Does this perturbation result in a significant change in IL8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1252
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and RP11-146D12.2 expression is measured. Determine whether RP11-146D12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and RP11-146D12.2 expression is measured. Determine whether RP11-146D12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":479
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and GPRC5C expression is quantified. Does this perturbation result in a significant change in GPRC5C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and GPRC5C expression is quantified. Does this perturbation result in a significant change in GPRC5C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2222
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor APOL4 expression. Decide whether this perturbation leads to a significant alteration in APOL4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor APOL4 expression. Decide whether this perturbation leads to a significant alteration in APOL4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":898
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of DOCK11 is measured. Determine whether DOCK11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of DOCK11 is measured. Determine whether DOCK11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":366
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of DNTTIP2. Does perturbing TIMM23 lead to a significant change in DNTTIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of DNTTIP2. Does perturbing TIMM23 lead to a significant change in DNTTIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":811
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of RP11-81A22.5. Does this perturbation cause a significant change in RP11-81A22.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of RP11-81A22.5. Does this perturbation cause a significant change in RP11-81A22.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1614
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of TMOD3 is measured. Does this perturbation cause a significant change in TMOD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of TMOD3 is measured. Does this perturbation cause a significant change in TMOD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1510
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor CDCA3 expression. Decide whether this perturbation leads to a significant alteration in CDCA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor CDCA3 expression. Decide whether this perturbation leads to a significant alteration in CDCA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4118
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor C6orf48 expression. Decide whether this perturbation leads to a significant alteration in C6orf48 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor C6orf48 expression. Decide whether this perturbation leads to a significant alteration in C6orf48 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in HM13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in HM13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4515
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RP11-141B14.1. Does this perturbation cause a significant change in RP11-141B14.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RP11-141B14.1. Does this perturbation cause a significant change in RP11-141B14.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor AC104532.4 expression. Decide whether this perturbation leads to a significant alteration in AC104532.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor AC104532.4 expression. Decide whether this perturbation leads to a significant alteration in AC104532.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2988
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of SRP72 is measured. Does this perturbation cause a significant change in SRP72 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of SRP72 is measured. Does this perturbation cause a significant change in SRP72 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1230
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor C19orf59 expression. Decide whether this perturbation leads to a significant alteration in C19orf59 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor C19orf59 expression. Decide whether this perturbation leads to a significant alteration in C19orf59 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2348
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of PTPRC. Does perturbing DDIT3 lead to a significant change in PTPRC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of PTPRC. Does perturbing DDIT3 lead to a significant change in PTPRC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":231
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of ASPM is measured. Determine whether ASPM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of ASPM is measured. Determine whether ASPM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2666
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of ZNF292 is measured. Does this perturbation cause a significant change in ZNF292 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of ZNF292 is measured. Does this perturbation cause a significant change in ZNF292 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3560
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and RP11-38P22.2 expression is observed. Does this perturbation lead to a significant difference in RP11-38P22.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and RP11-38P22.2 expression is observed. Does this perturbation lead to a significant difference in RP11-38P22.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1053
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of MARCH8 is measured. Does this perturbation cause a significant change in MARCH8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of MARCH8 is measured. Does this perturbation cause a significant change in MARCH8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1430
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of CHD3 is measured. Determine whether CHD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of CHD3 is measured. Determine whether CHD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4906
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and AKAP11 expression is measured. Determine whether AKAP11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and AKAP11 expression is measured. Determine whether AKAP11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1929
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor CTD-2001C12.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2001C12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor CTD-2001C12.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2001C12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":578
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of GMEB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of GMEB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1207
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of RP11-95O2.5 is measured. Does this perturbation cause a significant change in RP11-95O2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of RP11-95O2.5 is measured. Does this perturbation cause a significant change in RP11-95O2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4470
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and CDRT4 expression is measured. Determine whether CDRT4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and CDRT4 expression is measured. Determine whether CDRT4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":289
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and NFE2L3 expression is quantified. Does this perturbation result in a significant change in NFE2L3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and NFE2L3 expression is quantified. Does this perturbation result in a significant change in NFE2L3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4822
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and HERC2 expression is measured. Determine whether HERC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and HERC2 expression is measured. Determine whether HERC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":959
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of APOL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of APOL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":897
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and CCDC69 expression is quantified. Does this perturbation result in a significant change in CCDC69 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and CCDC69 expression is quantified. Does this perturbation result in a significant change in CCDC69 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3442
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of ZMYND8 is measured. Does this perturbation cause a significant change in ZMYND8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of ZMYND8 is measured. Does this perturbation cause a significant change in ZMYND8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1520
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor RNF8 expression. Decide whether this perturbation leads to a significant alteration in RNF8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor RNF8 expression. Decide whether this perturbation leads to a significant alteration in RNF8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3188
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in PARP11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in PARP11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3705
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2044
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of LINC01031 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of LINC01031 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4247
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in RP11-38P22.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in RP11-38P22.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1055
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":843
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of RGS20 is measured. Determine whether RGS20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of RGS20 is measured. Determine whether RGS20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3126
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and RNF8 expression is measured. Determine whether RNF8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and RNF8 expression is measured. Determine whether RNF8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3189
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of IL32. Does perturbing YIPF5 lead to a significant change in IL32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of IL32. Does perturbing YIPF5 lead to a significant change in IL32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":561
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and PLB1 expression is measured. Determine whether PLB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and PLB1 expression is measured. Determine whether PLB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4959
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and UBE3A expression is measured. Determine whether UBE3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and UBE3A expression is measured. Determine whether UBE3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1229
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor KLF6 expression. Decide whether this perturbation leads to a significant alteration in KLF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor KLF6 expression. Decide whether this perturbation leads to a significant alteration in KLF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2298
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and LINC00938 expression is measured. Determine whether LINC00938 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and LINC00938 expression is measured. Determine whether LINC00938 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4109
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RGS20 expression is observed. Does this perturbation lead to a significant difference in RGS20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and RGS20 expression is observed. Does this perturbation lead to a significant difference in RGS20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2713
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor TLN1 expression. Decide whether this perturbation leads to a significant alteration in TLN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor TLN1 expression. Decide whether this perturbation leads to a significant alteration in TLN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1038
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of LINC01137. Does perturbing EIF2B3 lead to a significant change in LINC01137 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of LINC01137. Does perturbing EIF2B3 lead to a significant change in LINC01137 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4661
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of TTC18 is measured. Determine whether TTC18 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of TTC18 is measured. Determine whether TTC18 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3696
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of CENPC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of CENPC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4457
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of OR2T6. Does this perturbation cause a significant change in OR2T6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of OR2T6. Does this perturbation cause a significant change in OR2T6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1844
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of MED13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of MED13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4317
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of DDX6. Does perturbing IER3IP1 lead to a significant change in DDX6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of DDX6. Does perturbing IER3IP1 lead to a significant change in DDX6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":521
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of FOXO6. Does perturbing UFM1 lead to a significant change in FOXO6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of FOXO6. Does perturbing UFM1 lead to a significant change in FOXO6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4121
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor PTAR1 expression. Decide whether this perturbation leads to a significant alteration in PTAR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor PTAR1 expression. Decide whether this perturbation leads to a significant alteration in PTAR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2108
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of CD58 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of CD58 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2497
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2724
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of HIST1H2AM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of HIST1H2AM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2427
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of CTBS is measured. Does this perturbation cause a significant change in CTBS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of CTBS is measured. Does this perturbation cause a significant change in CTBS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4440
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of POLR2J3. Does this perturbation cause a significant change in POLR2J3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of POLR2J3. Does this perturbation cause a significant change in POLR2J3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3794
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor AC012594.1 expression. Decide whether this perturbation leads to a significant alteration in AC012594.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor AC012594.1 expression. Decide whether this perturbation leads to a significant alteration in AC012594.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1678
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of OBSCN is measured. Determine whether OBSCN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of OBSCN is measured. Determine whether OBSCN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3826
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of MT2A. Does perturbing ARHGAP22 lead to a significant change in MT2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of MT2A. Does perturbing ARHGAP22 lead to a significant change in MT2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3161
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of RP11-322J23.1 is measured. Determine whether RP11-322J23.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of RP11-322J23.1 is measured. Determine whether RP11-322J23.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4726
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor CTSF expression. Decide whether this perturbation leads to a significant alteration in CTSF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor CTSF expression. Decide whether this perturbation leads to a significant alteration in CTSF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":158
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in EXOC3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in EXOC3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3355
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and TSPAN33 expression is observed. Does this perturbation lead to a significant difference in TSPAN33 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and TSPAN33 expression is observed. Does this perturbation lead to a significant difference in TSPAN33 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3523
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of RP11-328J2.1. Does this perturbation cause a significant change in RP11-328J2.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of RP11-328J2.1. Does this perturbation cause a significant change in RP11-328J2.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1094
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of SNRNP25 is measured. Determine whether SNRNP25 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of SNRNP25 is measured. Determine whether SNRNP25 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2156
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of EP400 is measured. Determine whether EP400 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of EP400 is measured. Determine whether EP400 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3666
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and VIM-AS1 expression is quantified. Does this perturbation result in a significant change in VIM-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and VIM-AS1 expression is quantified. Does this perturbation result in a significant change in VIM-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":482
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of PHF3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of PHF3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of SPEN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of SPEN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4087
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in AC018878.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in AC018878.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3285
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1139
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of EBI3. Does this perturbation cause a significant change in EBI3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of EBI3. Does this perturbation cause a significant change in EBI3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1654
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of S100A10. Does this perturbation cause a significant change in S100A10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of S100A10. Does this perturbation cause a significant change in S100A10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4874
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of GUSB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of GUSB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1407
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of TMEM60 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of TMEM60 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4977
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor WDR72 expression. Decide whether this perturbation leads to a significant alteration in WDR72 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor WDR72 expression. Decide whether this perturbation leads to a significant alteration in WDR72 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4138
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of PPP4R2. Does perturbing HSPA9 lead to a significant change in PPP4R2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of PPP4R2. Does perturbing HSPA9 lead to a significant change in PPP4R2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2371
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of ZC3H7A is measured. Does this perturbation cause a significant change in ZC3H7A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of ZC3H7A is measured. Does this perturbation cause a significant change in ZC3H7A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3670
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor ZMYND8 expression. Decide whether this perturbation leads to a significant alteration in ZMYND8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor ZMYND8 expression. Decide whether this perturbation leads to a significant alteration in ZMYND8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1528
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in CD58 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in CD58 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2495
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of CD58 is measured. Determine whether CD58 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of CD58 is measured. Determine whether CD58 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2496
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of RP11-640M9.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of RP11-640M9.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1127
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of C6orf120. Does perturbing NEDD8 lead to a significant change in C6orf120 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of C6orf120. Does perturbing NEDD8 lead to a significant change in C6orf120 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2261
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of LTN1 is measured. Determine whether LTN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of LTN1 is measured. Determine whether LTN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3786
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of TTC18 is measured. Does this perturbation cause a significant change in TTC18 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of TTC18 is measured. Does this perturbation cause a significant change in TTC18 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3690
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and ITGB2 expression is observed. Does this perturbation lead to a significant difference in ITGB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and ITGB2 expression is observed. Does this perturbation lead to a significant difference in ITGB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1303
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of TKTL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of TKTL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":177
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of HIST1H2BC. Does perturbing DNAJC19 lead to a significant change in HIST1H2BC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of HIST1H2BC. Does perturbing DNAJC19 lead to a significant change in HIST1H2BC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4771
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor IL8 expression. Decide whether this perturbation leads to a significant alteration in IL8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor IL8 expression. Decide whether this perturbation leads to a significant alteration in IL8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1258
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and PSMC1 expression is measured. Determine whether PSMC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and PSMC1 expression is measured. Determine whether PSMC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2829
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ROBO1 expression is observed. Does this perturbation lead to a significant difference in ROBO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ROBO1 expression is observed. Does this perturbation lead to a significant difference in ROBO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3943
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and RSAD2 expression is quantified. Does this perturbation result in a significant change in RSAD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and RSAD2 expression is quantified. Does this perturbation result in a significant change in RSAD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1462
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and RP11-157D23.2 expression is observed. Does this perturbation lead to a significant difference in RP11-157D23.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and RP11-157D23.2 expression is observed. Does this perturbation lead to a significant difference in RP11-157D23.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4423
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and NINJ2 expression is quantified. Does this perturbation result in a significant change in NINJ2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and NINJ2 expression is quantified. Does this perturbation result in a significant change in NINJ2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2142
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PSMD14 is measured. Does this perturbation cause a significant change in PSMD14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PSMD14 is measured. Does this perturbation cause a significant change in PSMD14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3100
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of RP11-360L9.8 is measured. Does this perturbation cause a significant change in RP11-360L9.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of RP11-360L9.8 is measured. Does this perturbation cause a significant change in RP11-360L9.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2790
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of RP11-38P22.2. Does perturbing IARS2 lead to a significant change in RP11-38P22.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of RP11-38P22.2. Does perturbing IARS2 lead to a significant change in RP11-38P22.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1051
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor SPINK5 expression. Decide whether this perturbation leads to a significant alteration in SPINK5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor SPINK5 expression. Decide whether this perturbation leads to a significant alteration in SPINK5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":418
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and SNHG7 expression is quantified. Does this perturbation result in a significant change in SNHG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and SNHG7 expression is quantified. Does this perturbation result in a significant change in SNHG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4042
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of HMGCS1. Does perturbing EIF2B4 lead to a significant change in HMGCS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of HMGCS1. Does perturbing EIF2B4 lead to a significant change in HMGCS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":371
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of GOT1 is measured. Does this perturbation cause a significant change in GOT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of GOT1 is measured. Does this perturbation cause a significant change in GOT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1110
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and COPB1 expression is measured. Determine whether COPB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and COPB1 expression is measured. Determine whether COPB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":809
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor EP400 expression. Decide whether this perturbation leads to a significant alteration in EP400 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor EP400 expression. Decide whether this perturbation leads to a significant alteration in EP400 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3668
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and RP11-81A22.5 expression is observed. Does this perturbation lead to a significant difference in RP11-81A22.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and RP11-81A22.5 expression is observed. Does this perturbation lead to a significant difference in RP11-81A22.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1613
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of OBSCN. Does this perturbation cause a significant change in OBSCN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of OBSCN. Does this perturbation cause a significant change in OBSCN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3824
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and H3F3B expression is observed. Does this perturbation lead to a significant difference in H3F3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and H3F3B expression is observed. Does this perturbation lead to a significant difference in H3F3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2323
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of ZNF292 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of ZNF292 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3567
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of CLDN11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of CLDN11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2617
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of RBM12B-AS1. Does perturbing GBF1 lead to a significant change in RBM12B-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of RBM12B-AS1. Does perturbing GBF1 lead to a significant change in RBM12B-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2511
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and FAM114A1 expression is quantified. Does this perturbation result in a significant change in FAM114A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and FAM114A1 expression is quantified. Does this perturbation result in a significant change in FAM114A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":712
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in CTD-2521M24.9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in CTD-2521M24.9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2995
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of TRAPPC10. Does perturbing GMPPB lead to a significant change in TRAPPC10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of TRAPPC10. Does perturbing GMPPB lead to a significant change in TRAPPC10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1851
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of AC015987.1 is measured. Determine whether AC015987.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of AC015987.1 is measured. Determine whether AC015987.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2256
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and C6orf48 expression is quantified. Does this perturbation result in a significant change in C6orf48 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and C6orf48 expression is quantified. Does this perturbation result in a significant change in C6orf48 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of MLEC. Does perturbing ARHGAP22 lead to a significant change in MLEC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of MLEC. Does perturbing ARHGAP22 lead to a significant change in MLEC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3171
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and RP11-363D14.1 expression is observed. Does this perturbation lead to a significant difference in RP11-363D14.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and RP11-363D14.1 expression is observed. Does this perturbation lead to a significant difference in RP11-363D14.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3053
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of CD9 is measured. Determine whether CD9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of CD9 is measured. Determine whether CD9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":426
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of CDRT4 is measured. Determine whether CDRT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of CDRT4 is measured. Determine whether CDRT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":286
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and WHAMM expression is observed. Does this perturbation lead to a significant difference in WHAMM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and WHAMM expression is observed. Does this perturbation lead to a significant difference in WHAMM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":783
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and KCNH7 expression is measured. Determine whether KCNH7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and KCNH7 expression is measured. Determine whether KCNH7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1789
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of TRIM24 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of TRIM24 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3197
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of HOTAIRM1. Does perturbing QARS lead to a significant change in HOTAIRM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of HOTAIRM1. Does perturbing QARS lead to a significant change in HOTAIRM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1261
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and RP11-640M9.1 expression is quantified. Does this perturbation result in a significant change in RP11-640M9.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and RP11-640M9.1 expression is quantified. Does this perturbation result in a significant change in RP11-640M9.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1122
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of IL32 is measured. Does this perturbation cause a significant change in IL32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of IL32 is measured. Does this perturbation cause a significant change in IL32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":560
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and UHRF1BP1L expression is observed. Does this perturbation lead to a significant difference in UHRF1BP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and UHRF1BP1L expression is observed. Does this perturbation lead to a significant difference in UHRF1BP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":243
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of MTPN is measured. Determine whether MTPN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of MTPN is measured. Determine whether MTPN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4736
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor POLR2J3 expression. Decide whether this perturbation leads to a significant alteration in POLR2J3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor POLR2J3 expression. Decide whether this perturbation leads to a significant alteration in POLR2J3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3798
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and LAMP2 expression is quantified. Does this perturbation result in a significant change in LAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and LAMP2 expression is quantified. Does this perturbation result in a significant change in LAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2772
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of BAMBI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of BAMBI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1177
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and RP11-119J18.1 expression is observed. Does this perturbation lead to a significant difference in RP11-119J18.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and RP11-119J18.1 expression is observed. Does this perturbation lead to a significant difference in RP11-119J18.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2443
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of WHSC1 is measured. Determine whether WHSC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of WHSC1 is measured. Determine whether WHSC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1486
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and IFT27 expression is measured. Determine whether IFT27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and IFT27 expression is measured. Determine whether IFT27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4229
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of ARHGAP11A. Does this perturbation cause a significant change in ARHGAP11A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of ARHGAP11A. Does this perturbation cause a significant change in ARHGAP11A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3724
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of CYP17A1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of CYP17A1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1247
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and PDE9A expression is measured. Determine whether PDE9A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and PDE9A expression is measured. Determine whether PDE9A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":199
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in TSNAXIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in TSNAXIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":755
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of ZNF280B is measured. Does this perturbation cause a significant change in ZNF280B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of ZNF280B is measured. Does this perturbation cause a significant change in ZNF280B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1280
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor GPR146 expression. Decide whether this perturbation leads to a significant alteration in GPR146 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor GPR146 expression. Decide whether this perturbation leads to a significant alteration in GPR146 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5088
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and YTHDF2 expression is measured. Determine whether YTHDF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and YTHDF2 expression is measured. Determine whether YTHDF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4929
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of CTNNB1. Does perturbing MRPL39 lead to a significant change in CTNNB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of CTNNB1. Does perturbing MRPL39 lead to a significant change in CTNNB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2451
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor SPEN expression. Decide whether this perturbation leads to a significant alteration in SPEN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor SPEN expression. Decide whether this perturbation leads to a significant alteration in SPEN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4088
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and FYTTD1 expression is measured. Determine whether FYTTD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and FYTTD1 expression is measured. Determine whether FYTTD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2369
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and HIST1H2AM expression is measured. Determine whether HIST1H2AM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and HIST1H2AM expression is measured. Determine whether HIST1H2AM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2429
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in CTBS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in CTBS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4445
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and RP11-435O5.4 expression is observed. Does this perturbation lead to a significant difference in RP11-435O5.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and RP11-435O5.4 expression is observed. Does this perturbation lead to a significant difference in RP11-435O5.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1193
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and ZFHX3 expression is measured. Determine whether ZFHX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4289
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of KIF4A. Does this perturbation cause a significant change in KIF4A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of KIF4A. Does this perturbation cause a significant change in KIF4A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2584
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of HIST1H2AC is measured. Does this perturbation cause a significant change in HIST1H2AC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of HIST1H2AC is measured. Does this perturbation cause a significant change in HIST1H2AC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3020
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of ATF6. Does perturbing AMIGO3 lead to a significant change in ATF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of ATF6. Does perturbing AMIGO3 lead to a significant change in ATF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":851
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of HIST1H2AM. Does perturbing MRPL39 lead to a significant change in HIST1H2AM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of HIST1H2AM. Does perturbing MRPL39 lead to a significant change in HIST1H2AM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2421
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of RP11-146D12.2 is measured. Determine whether RP11-146D12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of RP11-146D12.2 is measured. Determine whether RP11-146D12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":476
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in VIMP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in VIMP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":975
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of LTBP1. Does perturbing GMPPB lead to a significant change in LTBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of LTBP1. Does perturbing GMPPB lead to a significant change in LTBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1801
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor JARID2 expression. Decide whether this perturbation leads to a significant alteration in JARID2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor JARID2 expression. Decide whether this perturbation leads to a significant alteration in JARID2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1218
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of ZNF429. Does perturbing CREB1 lead to a significant change in ZNF429 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of ZNF429. Does perturbing CREB1 lead to a significant change in ZNF429 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor TAGLN expression. Decide whether this perturbation leads to a significant alteration in TAGLN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor TAGLN expression. Decide whether this perturbation leads to a significant alteration in TAGLN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1358
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of WHSC1 is measured. Does this perturbation cause a significant change in WHSC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of WHSC1 is measured. Does this perturbation cause a significant change in WHSC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1480
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of SERPING1. Does this perturbation cause a significant change in SERPING1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of SERPING1. Does this perturbation cause a significant change in SERPING1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3244
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and RP11-573D15.2 expression is observed. Does this perturbation lead to a significant difference in RP11-573D15.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and RP11-573D15.2 expression is observed. Does this perturbation lead to a significant difference in RP11-573D15.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3883
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of C9orf64 is measured. Does this perturbation cause a significant change in C9orf64 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of C9orf64 is measured. Does this perturbation cause a significant change in C9orf64 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3870
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in SNHG10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in SNHG10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1885
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4759
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and EP400 expression is observed. Does this perturbation lead to a significant difference in EP400 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and EP400 expression is observed. Does this perturbation lead to a significant difference in EP400 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3663
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of THBS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of THBS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5017
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of RP11-304M2.5 is measured. Does this perturbation cause a significant change in RP11-304M2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of RP11-304M2.5 is measured. Does this perturbation cause a significant change in RP11-304M2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4530
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and RCBTB2 expression is measured. Determine whether RCBTB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and RCBTB2 expression is measured. Determine whether RCBTB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1339
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and TMEM60 expression is quantified. Does this perturbation result in a significant change in TMEM60 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and TMEM60 expression is quantified. Does this perturbation result in a significant change in TMEM60 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3512
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of NAV2. Does perturbing CARS lead to a significant change in NAV2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of NAV2. Does perturbing CARS lead to a significant change in NAV2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4861
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of LINC01137. Does this perturbation cause a significant change in LINC01137 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of LINC01137. Does this perturbation cause a significant change in LINC01137 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4664
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in TNFRSF10B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in TNFRSF10B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2285
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of ATXN7L3B is measured. Does this perturbation cause a significant change in ATXN7L3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of ATXN7L3B is measured. Does this perturbation cause a significant change in ATXN7L3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4930
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of ABI2. Does perturbing GNPNAT1 lead to a significant change in ABI2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of ABI2. Does perturbing GNPNAT1 lead to a significant change in ABI2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2021
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of MARCH8 is measured. Determine whether MARCH8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of MARCH8 is measured. Determine whether MARCH8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1436
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and PKDCC expression is observed. Does this perturbation lead to a significant difference in PKDCC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and PKDCC expression is observed. Does this perturbation lead to a significant difference in PKDCC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1793
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and ARHGAP30 expression is observed. Does this perturbation lead to a significant difference in ARHGAP30 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and ARHGAP30 expression is observed. Does this perturbation lead to a significant difference in ARHGAP30 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1473
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of CENPC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of CENPC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2187
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of ROCK1 is measured. Determine whether ROCK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of ROCK1 is measured. Determine whether ROCK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5156
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and DST expression is measured. Determine whether DST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and DST expression is measured. Determine whether DST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3499
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of VIMP is measured. Determine whether VIMP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of VIMP is measured. Determine whether VIMP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4586
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of ATP5EP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of ATP5EP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2957
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of TRIM38. Does this perturbation cause a significant change in TRIM38 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of TRIM38. Does this perturbation cause a significant change in TRIM38 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3384
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of MYH7B is measured. Determine whether MYH7B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of MYH7B is measured. Determine whether MYH7B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":586
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of RGS20 is measured. Does this perturbation cause a significant change in RGS20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of RGS20 is measured. Does this perturbation cause a significant change in RGS20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4940
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor MORF4L2 expression. Decide whether this perturbation leads to a significant alteration in MORF4L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor MORF4L2 expression. Decide whether this perturbation leads to a significant alteration in MORF4L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2628
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of SERPINF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of SERPINF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3957
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of AC104532.4. Does this perturbation cause a significant change in AC104532.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of AC104532.4. Does this perturbation cause a significant change in AC104532.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2984
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and SPINK5 expression is observed. Does this perturbation lead to a significant difference in SPINK5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and SPINK5 expression is observed. Does this perturbation lead to a significant difference in SPINK5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":413
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and VPS41 expression is quantified. Does this perturbation result in a significant change in VPS41 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and VPS41 expression is quantified. Does this perturbation result in a significant change in VPS41 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":632
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor CTD-2267D19.3 expression. Decide whether this perturbation leads to a significant alteration in CTD-2267D19.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor CTD-2267D19.3 expression. Decide whether this perturbation leads to a significant alteration in CTD-2267D19.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1548
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and NXF1 expression is observed. Does this perturbation lead to a significant difference in NXF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and NXF1 expression is observed. Does this perturbation lead to a significant difference in NXF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3113
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of CTD-2587M2.1. Does perturbing CAD lead to a significant change in CTD-2587M2.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of CTD-2587M2.1. Does perturbing CAD lead to a significant change in CTD-2587M2.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1911
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of PAK1IP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of PAK1IP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4257
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and NUFIP2 expression is measured. Determine whether NUFIP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and NUFIP2 expression is measured. Determine whether NUFIP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2469
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and EP300 expression is observed. Does this perturbation lead to a significant difference in EP300 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and EP300 expression is observed. Does this perturbation lead to a significant difference in EP300 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1683
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2120
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of SEC23IP. Does this perturbation cause a significant change in SEC23IP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of SEC23IP. Does this perturbation cause a significant change in SEC23IP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3974
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor PARP11 expression. Decide whether this perturbation leads to a significant alteration in PARP11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor PARP11 expression. Decide whether this perturbation leads to a significant alteration in PARP11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3708
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and CST7 expression is quantified. Does this perturbation result in a significant change in CST7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and CST7 expression is quantified. Does this perturbation result in a significant change in CST7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2202
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of GSN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of GSN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3207
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of C10orf32. Does this perturbation cause a significant change in C10orf32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of C10orf32. Does this perturbation cause a significant change in C10orf32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3044
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of OXLD1 is measured. Does this perturbation cause a significant change in OXLD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of OXLD1 is measured. Does this perturbation cause a significant change in OXLD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2850
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor AC096559.1 expression. Decide whether this perturbation leads to a significant alteration in AC096559.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor AC096559.1 expression. Decide whether this perturbation leads to a significant alteration in AC096559.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1878
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of HIST1H1D. Does this perturbation cause a significant change in HIST1H1D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of HIST1H1D. Does this perturbation cause a significant change in HIST1H1D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4344
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of UHMK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of UHMK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4987
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of AC005540.3. Does perturbing FECH lead to a significant change in AC005540.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of AC005540.3. Does perturbing FECH lead to a significant change in AC005540.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4411
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and RP11-573D15.9 expression is measured. Determine whether RP11-573D15.9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and RP11-573D15.9 expression is measured. Determine whether RP11-573D15.9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1299
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and OPTN expression is measured. Determine whether OPTN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and OPTN expression is measured. Determine whether OPTN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":559
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of PAK1IP1 is measured. Does this perturbation cause a significant change in PAK1IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of PAK1IP1 is measured. Does this perturbation cause a significant change in PAK1IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4250
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor KIAA1731 expression. Decide whether this perturbation leads to a significant alteration in KIAA1731 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor KIAA1731 expression. Decide whether this perturbation leads to a significant alteration in KIAA1731 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4898
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in ZNF341 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in ZNF341 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3775
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of BRWD3 is measured. Determine whether BRWD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of BRWD3 is measured. Determine whether BRWD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":736
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and DUT expression is quantified. Does this perturbation result in a significant change in DUT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and DUT expression is quantified. Does this perturbation result in a significant change in DUT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":272
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and RP11-242O24.5 expression is measured. Determine whether RP11-242O24.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and RP11-242O24.5 expression is measured. Determine whether RP11-242O24.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3999
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RP11-141B14.1 is measured. Determine whether RP11-141B14.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RP11-141B14.1 is measured. Determine whether RP11-141B14.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and HIST1H3D expression is observed. Does this perturbation lead to a significant difference in HIST1H3D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and HIST1H3D expression is observed. Does this perturbation lead to a significant difference in HIST1H3D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":913
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of IRF7. Does perturbing IER3IP1 lead to a significant change in IRF7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of IRF7. Does perturbing IER3IP1 lead to a significant change in IRF7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":531
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of HIST1H2AM is measured. Determine whether HIST1H2AM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of HIST1H2AM is measured. Determine whether HIST1H2AM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":386
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and CELF6 expression is measured. Determine whether CELF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and CELF6 expression is measured. Determine whether CELF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5039
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and TROAP expression is observed. Does this perturbation lead to a significant difference in TROAP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and TROAP expression is observed. Does this perturbation lead to a significant difference in TROAP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3083
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of QSER1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of QSER1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3007
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of RP11-3D4.3. Does perturbing EIF2S1 lead to a significant change in RP11-3D4.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of RP11-3D4.3. Does perturbing EIF2S1 lead to a significant change in RP11-3D4.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3641
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and RP11-212I21.4 expression is measured. Determine whether RP11-212I21.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and RP11-212I21.4 expression is measured. Determine whether RP11-212I21.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2039
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of OR2T6. Does perturbing GMPPB lead to a significant change in OR2T6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of OR2T6. Does perturbing GMPPB lead to a significant change in OR2T6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1841
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and ATP5EP2 expression is quantified. Does this perturbation result in a significant change in ATP5EP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and ATP5EP2 expression is quantified. Does this perturbation result in a significant change in ATP5EP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2952
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor LINC01137 expression. Decide whether this perturbation leads to a significant alteration in LINC01137 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor LINC01137 expression. Decide whether this perturbation leads to a significant alteration in LINC01137 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4668
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of CENPF. Does perturbing CCND3 lead to a significant change in CENPF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of CENPF. Does perturbing CCND3 lead to a significant change in CENPF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4061
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of VIM-AS1 is measured. Does this perturbation cause a significant change in VIM-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of VIM-AS1 is measured. Does this perturbation cause a significant change in VIM-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1720
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of WHAMM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of WHAMM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":787
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of TTC32 is measured. Does this perturbation cause a significant change in TTC32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of TTC32 is measured. Does this perturbation cause a significant change in TTC32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3210
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in HIST1H2AM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in HIST1H2AM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":385
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor DKFZP779L1853 expression. Decide whether this perturbation leads to a significant alteration in DKFZP779L1853 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor DKFZP779L1853 expression. Decide whether this perturbation leads to a significant alteration in DKFZP779L1853 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2388
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and IFT27 expression is observed. Does this perturbation lead to a significant difference in IFT27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and IFT27 expression is observed. Does this perturbation lead to a significant difference in IFT27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4223
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of NBEAL2 is measured. Determine whether NBEAL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of NBEAL2 is measured. Determine whether NBEAL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and ARHGAP6 expression is measured. Determine whether ARHGAP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and ARHGAP6 expression is measured. Determine whether ARHGAP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1759
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of RP11-38P22.2. Does this perturbation cause a significant change in RP11-38P22.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of RP11-38P22.2. Does this perturbation cause a significant change in RP11-38P22.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1054
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and TET1 expression is quantified. Does this perturbation result in a significant change in TET1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and TET1 expression is quantified. Does this perturbation result in a significant change in TET1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":132
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of LST1. Does perturbing DNAJC19 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of LST1. Does perturbing DNAJC19 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4751
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in MLEC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in MLEC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3175
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of CCDC69 is measured. Determine whether CCDC69 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of CCDC69 is measured. Determine whether CCDC69 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3446
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of PPM1N. Does this perturbation cause a significant change in PPM1N expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of PPM1N. Does this perturbation cause a significant change in PPM1N expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3924
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of RTN2. Does perturbing TTI2 lead to a significant change in RTN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of RTN2. Does perturbing TTI2 lead to a significant change in RTN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2061
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in PPM1N expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in PPM1N expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3925
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and ZEB1 expression is measured. Determine whether ZEB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and ZEB1 expression is measured. Determine whether ZEB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1389
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of GOT1. Does perturbing SOCS1 lead to a significant change in GOT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of GOT1. Does perturbing SOCS1 lead to a significant change in GOT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1111
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in RAD51AP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in RAD51AP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5145
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of NOXA1 is measured. Does this perturbation cause a significant change in NOXA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of NOXA1 is measured. Does this perturbation cause a significant change in NOXA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1410
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of ATF7IP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of ATF7IP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4527
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of CTD-2001C12.1. Does this perturbation cause a significant change in CTD-2001C12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of CTD-2001C12.1. Does this perturbation cause a significant change in CTD-2001C12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":574
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of RNF19A is measured. Does this perturbation cause a significant change in RNF19A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of RNF19A is measured. Does this perturbation cause a significant change in RNF19A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3760
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and C9orf64 expression is observed. Does this perturbation lead to a significant difference in C9orf64 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and C9orf64 expression is observed. Does this perturbation lead to a significant difference in C9orf64 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3873
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in C17orf64 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in C17orf64 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3715
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of NOX5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of NOX5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3417
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of ABI2 is measured. Determine whether ABI2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of ABI2 is measured. Determine whether ABI2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2026
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2730
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of CTD-2587M2.1 is measured. Determine whether CTD-2587M2.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of CTD-2587M2.1 is measured. Determine whether CTD-2587M2.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1916
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of PIK3IP1. Does this perturbation cause a significant change in PIK3IP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of PIK3IP1. Does this perturbation cause a significant change in PIK3IP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2864
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of SMIM14. Does perturbing PSMD4 lead to a significant change in SMIM14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of SMIM14. Does perturbing PSMD4 lead to a significant change in SMIM14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3301
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of RP11-16E12.1. Does this perturbation cause a significant change in RP11-16E12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of RP11-16E12.1. Does this perturbation cause a significant change in RP11-16E12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3234
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of PGM3 is measured. Does this perturbation cause a significant change in PGM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of PGM3 is measured. Does this perturbation cause a significant change in PGM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2080
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of RP11-90P5.2 is measured. Determine whether RP11-90P5.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of RP11-90P5.2 is measured. Determine whether RP11-90P5.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":406
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of SMIM14 is measured. Does this perturbation cause a significant change in SMIM14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of SMIM14 is measured. Does this perturbation cause a significant change in SMIM14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3300
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of HLA-E. Does perturbing HSPA5 lead to a significant change in HLA-E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of HLA-E. Does perturbing HSPA5 lead to a significant change in HLA-E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3261
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and PPP1R16B expression is observed. Does this perturbation lead to a significant difference in PPP1R16B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and PPP1R16B expression is observed. Does this perturbation lead to a significant difference in PPP1R16B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4483
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and IDS expression is quantified. Does this perturbation result in a significant change in IDS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and IDS expression is quantified. Does this perturbation result in a significant change in IDS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4272
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in CTD-2001C12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in CTD-2001C12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":575
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of S100A13 is measured. Determine whether S100A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of S100A13 is measured. Determine whether S100A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2786
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of PTPN11 is measured. Does this perturbation cause a significant change in PTPN11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of PTPN11 is measured. Does this perturbation cause a significant change in PTPN11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":500
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in TRAPPC10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in TRAPPC10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1855
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of NOX5 is measured. Does this perturbation cause a significant change in NOX5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of NOX5 is measured. Does this perturbation cause a significant change in NOX5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3410
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of RP11-146D12.2 is measured. Does this perturbation cause a significant change in RP11-146D12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of RP11-146D12.2 is measured. Does this perturbation cause a significant change in RP11-146D12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":470
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of EIF3A is measured. Does this perturbation cause a significant change in EIF3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of EIF3A is measured. Does this perturbation cause a significant change in EIF3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4800
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and WDR72 expression is measured. Determine whether WDR72 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and WDR72 expression is measured. Determine whether WDR72 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4139
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and RP11-838N2.4 expression is measured. Determine whether RP11-838N2.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and RP11-838N2.4 expression is measured. Determine whether RP11-838N2.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3039
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of PTPRC. Does this perturbation cause a significant change in PTPRC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of PTPRC. Does this perturbation cause a significant change in PTPRC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":234
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of GNPTG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of GNPTG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3097
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of FAM114A1. Does this perturbation cause a significant change in FAM114A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of FAM114A1. Does this perturbation cause a significant change in FAM114A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":714
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and GUSB expression is measured. Determine whether GUSB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and GUSB expression is measured. Determine whether GUSB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1939
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and AMOTL1 expression is observed. Does this perturbation lead to a significant difference in AMOTL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and AMOTL1 expression is observed. Does this perturbation lead to a significant difference in AMOTL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2243
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in QSER1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in QSER1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5005
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and EP300 expression is measured. Determine whether EP300 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and EP300 expression is measured. Determine whether EP300 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1689
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in CASP8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in CASP8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":225
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of EBI3 is measured. Does this perturbation cause a significant change in EBI3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of EBI3 is measured. Does this perturbation cause a significant change in EBI3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1650
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of RIMS3. Does perturbing BHLHE40 lead to a significant change in RIMS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of RIMS3. Does perturbing BHLHE40 lead to a significant change in RIMS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":161
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and TIPARP expression is observed. Does this perturbation lead to a significant difference in TIPARP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and TIPARP expression is observed. Does this perturbation lead to a significant difference in TIPARP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3613
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and HLA-E expression is quantified. Does this perturbation result in a significant change in HLA-E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and HLA-E expression is quantified. Does this perturbation result in a significant change in HLA-E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3262
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of C6orf48. Does this perturbation cause a significant change in C6orf48 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of C6orf48. Does this perturbation cause a significant change in C6orf48 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in FCGRT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in FCGRT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3535
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of SNHG10. Does perturbing QARS lead to a significant change in SNHG10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of SNHG10. Does perturbing QARS lead to a significant change in SNHG10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1311
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and TMEM87B expression is quantified. Does this perturbation result in a significant change in TMEM87B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and TMEM87B expression is quantified. Does this perturbation result in a significant change in TMEM87B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":822
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor RGS20 expression. Decide whether this perturbation leads to a significant alteration in RGS20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor RGS20 expression. Decide whether this perturbation leads to a significant alteration in RGS20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4948
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of RP1-274L7.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of RP1-274L7.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4077
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of NSD1 is measured. Does this perturbation cause a significant change in NSD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of NSD1 is measured. Does this perturbation cause a significant change in NSD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1340
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in CFH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in CFH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5055
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of PCK2. Does perturbing EIF2B2 lead to a significant change in PCK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of PCK2. Does perturbing EIF2B2 lead to a significant change in PCK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3011
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor RP1-274L7.1 expression. Decide whether this perturbation leads to a significant alteration in RP1-274L7.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor RP1-274L7.1 expression. Decide whether this perturbation leads to a significant alteration in RP1-274L7.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4078
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor ATP6AP2 expression. Decide whether this perturbation leads to a significant alteration in ATP6AP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor ATP6AP2 expression. Decide whether this perturbation leads to a significant alteration in ATP6AP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1628
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of MED13 is measured. Does this perturbation cause a significant change in MED13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of MED13 is measured. Does this perturbation cause a significant change in MED13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4310
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and ATF7IP2 expression is quantified. Does this perturbation result in a significant change in ATF7IP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and ATF7IP2 expression is quantified. Does this perturbation result in a significant change in ATF7IP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4522
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor NOX5 expression. Decide whether this perturbation leads to a significant alteration in NOX5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor NOX5 expression. Decide whether this perturbation leads to a significant alteration in NOX5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3418
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2532
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of REST. Does perturbing TIMM23 lead to a significant change in REST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of REST. Does perturbing TIMM23 lead to a significant change in REST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":791
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and EPS15 expression is quantified. Does this perturbation result in a significant change in EPS15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and EPS15 expression is quantified. Does this perturbation result in a significant change in EPS15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4842
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and UFD1L expression is observed. Does this perturbation lead to a significant difference in UFD1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and UFD1L expression is observed. Does this perturbation lead to a significant difference in UFD1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2503
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and RILPL2 expression is observed. Does this perturbation lead to a significant difference in RILPL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and RILPL2 expression is observed. Does this perturbation lead to a significant difference in RILPL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4143
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of MYH7B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of MYH7B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":587
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and UBE3A expression is observed. Does this perturbation lead to a significant difference in UBE3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and UBE3A expression is observed. Does this perturbation lead to a significant difference in UBE3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1223
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of TIPARP. Does this perturbation cause a significant change in TIPARP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of TIPARP. Does this perturbation cause a significant change in TIPARP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3614
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and GRN expression is quantified. Does this perturbation result in a significant change in GRN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and GRN expression is quantified. Does this perturbation result in a significant change in GRN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4332
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of C12orf44. Does this perturbation cause a significant change in C12orf44 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of C12orf44. Does this perturbation cause a significant change in C12orf44 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1534
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in UQCRB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in UQCRB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":705
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor SPAST expression. Decide whether this perturbation leads to a significant alteration in SPAST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor SPAST expression. Decide whether this perturbation leads to a significant alteration in SPAST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2848
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor ARHGDIB expression. Decide whether this perturbation leads to a significant alteration in ARHGDIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor ARHGDIB expression. Decide whether this perturbation leads to a significant alteration in ARHGDIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1968
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of ERP29 is measured. Determine whether ERP29 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of ERP29 is measured. Determine whether ERP29 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5076
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of AC079466.1. Does perturbing MRGBP lead to a significant change in AC079466.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of AC079466.1. Does perturbing MRGBP lead to a significant change in AC079466.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1441
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and PTPRC expression is quantified. Does this perturbation result in a significant change in PTPRC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and PTPRC expression is quantified. Does this perturbation result in a significant change in PTPRC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":232
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of GCKR is measured. Determine whether GCKR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of GCKR is measured. Determine whether GCKR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4306
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and CD46 expression is measured. Determine whether CD46 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and CD46 expression is measured. Determine whether CD46 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4219
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of EXOC3L2 is measured. Does this perturbation cause a significant change in EXOC3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of EXOC3L2 is measured. Does this perturbation cause a significant change in EXOC3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3350
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor CDK13 expression. Decide whether this perturbation leads to a significant alteration in CDK13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor CDK13 expression. Decide whether this perturbation leads to a significant alteration in CDK13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2768
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and CRNDE expression is measured. Determine whether CRNDE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and CRNDE expression is measured. Determine whether CRNDE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1979
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of FAM212A is measured. Does this perturbation cause a significant change in FAM212A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of FAM212A is measured. Does this perturbation cause a significant change in FAM212A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2230
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of RP11-573D15.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of RP11-573D15.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3887
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of PELO is measured. Determine whether PELO shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of PELO is measured. Determine whether PELO shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2116
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of PDK2. Does perturbing DERL2 lead to a significant change in PDK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of PDK2. Does perturbing DERL2 lead to a significant change in PDK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2161
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of C6orf48 is measured. Determine whether C6orf48 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of C6orf48 is measured. Determine whether C6orf48 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of ARHGAP6 is measured. Determine whether ARHGAP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of ARHGAP6 is measured. Determine whether ARHGAP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1756
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of PIK3R3 is measured. Does this perturbation cause a significant change in PIK3R3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of PIK3R3 is measured. Does this perturbation cause a significant change in PIK3R3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4020
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of PELO. Does this perturbation cause a significant change in PELO expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of PELO. Does this perturbation cause a significant change in PELO expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3984
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and CASP4 expression is measured. Determine whether CASP4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and CASP4 expression is measured. Determine whether CASP4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of STC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of STC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":187
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of CTSF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of CTSF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":157
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in JARID2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in JARID2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1215
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor UFD1L expression. Decide whether this perturbation leads to a significant alteration in UFD1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor UFD1L expression. Decide whether this perturbation leads to a significant alteration in UFD1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2508
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and TLN1 expression is measured. Determine whether TLN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and TLN1 expression is measured. Determine whether TLN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1039
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of RP11-138C9.1 is measured. Determine whether RP11-138C9.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of RP11-138C9.1 is measured. Determine whether RP11-138C9.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":836
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of SBF2. Does perturbing FARSB lead to a significant change in SBF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of SBF2. Does perturbing FARSB lead to a significant change in SBF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2561
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor TMEM60 expression. Decide whether this perturbation leads to a significant alteration in TMEM60 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor TMEM60 expression. Decide whether this perturbation leads to a significant alteration in TMEM60 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3518
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in DNASE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in DNASE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1635
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor IL18R1 expression. Decide whether this perturbation leads to a significant alteration in IL18R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor IL18R1 expression. Decide whether this perturbation leads to a significant alteration in IL18R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4208
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and ARHGAP30 expression is quantified. Does this perturbation result in a significant change in ARHGAP30 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and ARHGAP30 expression is quantified. Does this perturbation result in a significant change in ARHGAP30 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1472
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of RP13-216E22.4. Does this perturbation cause a significant change in RP13-216E22.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of RP13-216E22.4. Does this perturbation cause a significant change in RP13-216E22.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2434
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor DST expression. Decide whether this perturbation leads to a significant alteration in DST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor DST expression. Decide whether this perturbation leads to a significant alteration in DST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3498
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and ANPEP expression is observed. Does this perturbation lead to a significant difference in ANPEP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and ANPEP expression is observed. Does this perturbation lead to a significant difference in ANPEP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4793
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of TLK2 is measured. Does this perturbation cause a significant change in TLK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of TLK2 is measured. Does this perturbation cause a significant change in TLK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4760
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in SLC37A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in SLC37A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1155
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor TAP1 expression. Decide whether this perturbation leads to a significant alteration in TAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor TAP1 expression. Decide whether this perturbation leads to a significant alteration in TAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4718
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and AC005540.3 expression is quantified. Does this perturbation result in a significant change in AC005540.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and AC005540.3 expression is quantified. Does this perturbation result in a significant change in AC005540.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4412
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of QSER1. Does perturbing P4HB lead to a significant change in QSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of QSER1. Does perturbing P4HB lead to a significant change in QSER1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5001
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and DDX6 expression is observed. Does this perturbation lead to a significant difference in DDX6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and DDX6 expression is observed. Does this perturbation lead to a significant difference in DDX6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":523
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of SERPINF2. Does perturbing SLC35B1 lead to a significant change in SERPINF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of SERPINF2. Does perturbing SLC35B1 lead to a significant change in SERPINF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3951
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of RP11-24F11.2. Does this perturbation cause a significant change in RP11-24F11.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of RP11-24F11.2. Does this perturbation cause a significant change in RP11-24F11.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1494
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in P4HB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in P4HB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4615
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":317
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor ARHGAP11A expression. Decide whether this perturbation leads to a significant alteration in ARHGAP11A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor ARHGAP11A expression. Decide whether this perturbation leads to a significant alteration in ARHGAP11A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3728
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in RP11-789C1.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in RP11-789C1.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":945
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of CDT1. Does perturbing SPCS2 lead to a significant change in CDT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of CDT1. Does perturbing SPCS2 lead to a significant change in CDT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5121
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of PDE9A is measured. Determine whether PDE9A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of PDE9A is measured. Determine whether PDE9A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":196
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and PIK3R1 expression is measured. Determine whether PIK3R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and PIK3R1 expression is measured. Determine whether PIK3R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5109
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4752
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of DUSP21. Does perturbing MARS lead to a significant change in DUSP21 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of DUSP21. Does perturbing MARS lead to a significant change in DUSP21 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2741
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of ROCK1. Does perturbing SPCS2 lead to a significant change in ROCK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of ROCK1. Does perturbing SPCS2 lead to a significant change in ROCK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5151
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of RASGRP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of RASGRP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4267
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and NSD1 expression is observed. Does this perturbation lead to a significant difference in NSD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and NSD1 expression is observed. Does this perturbation lead to a significant difference in NSD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1343
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of LTN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of LTN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3137
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor IL2RB expression. Decide whether this perturbation leads to a significant alteration in IL2RB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor IL2RB expression. Decide whether this perturbation leads to a significant alteration in IL2RB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4008
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of KCNH7. Does perturbing MTHFD1 lead to a significant change in KCNH7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of KCNH7. Does perturbing MTHFD1 lead to a significant change in KCNH7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1781
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of ZNF280B. Does this perturbation cause a significant change in ZNF280B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of ZNF280B. Does this perturbation cause a significant change in ZNF280B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1284
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of IL13RA1 is measured. Determine whether IL13RA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of IL13RA1 is measured. Determine whether IL13RA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2356
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of HIST1H3D is measured. Determine whether HIST1H3D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of HIST1H3D is measured. Determine whether HIST1H3D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":916
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and PTPRC expression is observed. Does this perturbation lead to a significant difference in PTPRC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and PTPRC expression is observed. Does this perturbation lead to a significant difference in PTPRC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":233
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of EP300 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of EP300 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2057
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of SPEN is measured. Determine whether SPEN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of SPEN is measured. Determine whether SPEN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1576
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RAI14 expression. Decide whether this perturbation leads to a significant alteration in RAI14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RAI14 expression. Decide whether this perturbation leads to a significant alteration in RAI14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2708
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and TLK2 expression is measured. Determine whether TLK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and TLK2 expression is measured. Determine whether TLK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4769
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of UBE2V1. Does this perturbation cause a significant change in UBE2V1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of UBE2V1. Does this perturbation cause a significant change in UBE2V1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1704
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and ZNF341 expression is quantified. Does this perturbation result in a significant change in ZNF341 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and ZNF341 expression is quantified. Does this perturbation result in a significant change in ZNF341 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3772
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of RP11-381O7.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of RP11-381O7.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1557
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of CASP8. Does perturbing DDIT3 lead to a significant change in CASP8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of CASP8. Does perturbing DDIT3 lead to a significant change in CASP8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":221
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor TRPM4 expression. Decide whether this perturbation leads to a significant alteration in TRPM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor TRPM4 expression. Decide whether this perturbation leads to a significant alteration in TRPM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3848
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of SNHG10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of SNHG10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1887
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in CD46 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in CD46 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4215
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in STARD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in STARD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4605
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of TSC22D4. Does this perturbation cause a significant change in TSC22D4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of TSC22D4. Does this perturbation cause a significant change in TSC22D4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3274
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor GSN expression. Decide whether this perturbation leads to a significant alteration in GSN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor GSN expression. Decide whether this perturbation leads to a significant alteration in GSN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3208
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of SLBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of SLBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2137
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of JUND is measured. Does this perturbation cause a significant change in JUND expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of JUND is measured. Does this perturbation cause a significant change in JUND expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":770
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of RSAD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of RSAD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1467
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of TOPBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of TOPBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3807
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and RBM12B-AS1 expression is quantified. Does this perturbation result in a significant change in RBM12B-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and RBM12B-AS1 expression is quantified. Does this perturbation result in a significant change in RBM12B-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2512
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of NFE2L3. Does this perturbation cause a significant change in NFE2L3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of NFE2L3. Does this perturbation cause a significant change in NFE2L3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1584
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of CDT1 is measured. Determine whether CDT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of CDT1 is measured. Determine whether CDT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5126
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of CELF6 is measured. Determine whether CELF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of CELF6 is measured. Determine whether CELF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5036
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor P4HB expression. Decide whether this perturbation leads to a significant alteration in P4HB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor P4HB expression. Decide whether this perturbation leads to a significant alteration in P4HB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4618
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of PTPRC is measured. Does this perturbation cause a significant change in PTPRC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of PTPRC is measured. Does this perturbation cause a significant change in PTPRC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":230
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and DNTTIP2 expression is quantified. Does this perturbation result in a significant change in DNTTIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and DNTTIP2 expression is quantified. Does this perturbation result in a significant change in DNTTIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":812
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and UBE3A expression is quantified. Does this perturbation result in a significant change in UBE3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and UBE3A expression is quantified. Does this perturbation result in a significant change in UBE3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1222
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in USP37 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in USP37 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1735
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor NPAT expression. Decide whether this perturbation leads to a significant alteration in NPAT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor NPAT expression. Decide whether this perturbation leads to a significant alteration in NPAT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3328
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of ESCO1. Does this perturbation cause a significant change in ESCO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of ESCO1. Does this perturbation cause a significant change in ESCO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":864
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of SPEN is measured. Does this perturbation cause a significant change in SPEN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of SPEN is measured. Does this perturbation cause a significant change in SPEN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4080
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of ANKRD33 is measured. Determine whether ANKRD33 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of ANKRD33 is measured. Determine whether ANKRD33 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4186
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of CTNNB1. Does this perturbation cause a significant change in CTNNB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of CTNNB1. Does this perturbation cause a significant change in CTNNB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2454
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of ANKRD33 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of ANKRD33 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4187
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and RP11-573D15.2 expression is measured. Determine whether RP11-573D15.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and RP11-573D15.2 expression is measured. Determine whether RP11-573D15.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3889
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of HIST1H2AM is measured. Does this perturbation cause a significant change in HIST1H2AM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of HIST1H2AM is measured. Does this perturbation cause a significant change in HIST1H2AM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":380
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and IL18R1 expression is measured. Determine whether IL18R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and IL18R1 expression is measured. Determine whether IL18R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4209
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of KDM1B. Does this perturbation cause a significant change in KDM1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of KDM1B. Does this perturbation cause a significant change in KDM1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1164
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in RP11-435O5.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in RP11-435O5.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1195
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of TACC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of TACC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1867
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in EIF4B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in EIF4B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4965
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and KCTD19 expression is quantified. Does this perturbation result in a significant change in KCTD19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and KCTD19 expression is quantified. Does this perturbation result in a significant change in KCTD19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2682
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of ZNF341 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of ZNF341 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3777
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of HPCAL1. Does this perturbation cause a significant change in HPCAL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of HPCAL1. Does this perturbation cause a significant change in HPCAL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2974
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of PPP1R16B is measured. Does this perturbation cause a significant change in PPP1R16B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of PPP1R16B is measured. Does this perturbation cause a significant change in PPP1R16B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4480
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of S100A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of S100A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2787
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and PIK3IP1 expression is quantified. Does this perturbation result in a significant change in PIK3IP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and PIK3IP1 expression is quantified. Does this perturbation result in a significant change in PIK3IP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2862
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of HPCAL1 is measured. Does this perturbation cause a significant change in HPCAL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of HPCAL1 is measured. Does this perturbation cause a significant change in HPCAL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2970
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of WHAMM is measured. Determine whether WHAMM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of WHAMM is measured. Determine whether WHAMM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":786
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in CLINT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in CLINT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":435
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of PRSS57. Does perturbing TMEM167A lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of PRSS57. Does perturbing TMEM167A lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1951
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of LTBP1 is measured. Determine whether LTBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of LTBP1 is measured. Determine whether LTBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1806
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PIF1. Does perturbing SARS lead to a significant change in PIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PIF1. Does perturbing SARS lead to a significant change in PIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3071
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and CHD3 expression is observed. Does this perturbation lead to a significant difference in CHD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and CHD3 expression is observed. Does this perturbation lead to a significant difference in CHD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4903
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2090
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of LTN1 is measured. Determine whether LTN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of LTN1 is measured. Determine whether LTN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3136
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RP11-685N10.1 is measured. Does this perturbation cause a significant change in RP11-685N10.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RP11-685N10.1 is measured. Does this perturbation cause a significant change in RP11-685N10.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2750
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and HLA-AS1 expression is observed. Does this perturbation lead to a significant difference in HLA-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and HLA-AS1 expression is observed. Does this perturbation lead to a significant difference in HLA-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":763
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of SP100 is measured. Determine whether SP100 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of SP100 is measured. Determine whether SP100 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1146
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of BAMBI is measured. Does this perturbation cause a significant change in BAMBI expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of BAMBI is measured. Does this perturbation cause a significant change in BAMBI expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1170
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1958
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of SLC25A35 is measured. Determine whether SLC25A35 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of SLC25A35 is measured. Determine whether SLC25A35 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3156
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and C12orf23 expression is measured. Determine whether C12orf23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and C12orf23 expression is measured. Determine whether C12orf23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1769
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RIOK3 expression is observed. Does this perturbation lead to a significant difference in RIOK3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RIOK3 expression is observed. Does this perturbation lead to a significant difference in RIOK3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and HAGH expression is quantified. Does this perturbation result in a significant change in HAGH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and HAGH expression is quantified. Does this perturbation result in a significant change in HAGH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2632
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of RP11-573D15.9 is measured. Determine whether RP11-573D15.9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of RP11-573D15.9 is measured. Determine whether RP11-573D15.9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1296
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2096
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor USP34 expression. Decide whether this perturbation leads to a significant alteration in USP34 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor USP34 expression. Decide whether this perturbation leads to a significant alteration in USP34 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4368
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PSMD14 is measured. Determine whether PSMD14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PSMD14 is measured. Determine whether PSMD14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3106
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and CD58 expression is quantified. Does this perturbation result in a significant change in CD58 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and CD58 expression is quantified. Does this perturbation result in a significant change in CD58 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2492
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of LTN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of LTN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3787
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor NRIP1 expression. Decide whether this perturbation leads to a significant alteration in NRIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor NRIP1 expression. Decide whether this perturbation leads to a significant alteration in NRIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3628
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of GUSB. Does this perturbation cause a significant change in GUSB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of GUSB. Does this perturbation cause a significant change in GUSB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1404
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of OXLD1 is measured. Determine whether OXLD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of OXLD1 is measured. Determine whether OXLD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2856
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and RP11-157D23.2 expression is quantified. Does this perturbation result in a significant change in RP11-157D23.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and RP11-157D23.2 expression is quantified. Does this perturbation result in a significant change in RP11-157D23.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4422
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of PELO. Does perturbing TMED10 lead to a significant change in PELO expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of PELO. Does perturbing TMED10 lead to a significant change in PELO expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3981
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in DDX3X expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in DDX3X expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1085
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of PARP11 is measured. Does this perturbation cause a significant change in PARP11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of PARP11 is measured. Does this perturbation cause a significant change in PARP11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3700
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2537
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor ERV3-1 expression. Decide whether this perturbation leads to a significant alteration in ERV3-1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor ERV3-1 expression. Decide whether this perturbation leads to a significant alteration in ERV3-1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":468
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of KIAA1586 is measured. Determine whether KIAA1586 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of KIAA1586 is measured. Determine whether KIAA1586 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4656
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of EP300 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of EP300 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1687
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of RP11-328J2.1 is measured. Does this perturbation cause a significant change in RP11-328J2.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of RP11-328J2.1 is measured. Does this perturbation cause a significant change in RP11-328J2.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1090
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in RP11-434H6.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in RP11-434H6.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1895
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of GMEB1 is measured. Does this perturbation cause a significant change in GMEB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of GMEB1 is measured. Does this perturbation cause a significant change in GMEB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1200
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of HERPUD1. Does perturbing FECH lead to a significant change in HERPUD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of HERPUD1. Does perturbing FECH lead to a significant change in HERPUD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4431
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of HIST1H3D. Does this perturbation cause a significant change in HIST1H3D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of HIST1H3D. Does this perturbation cause a significant change in HIST1H3D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":914
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of SIGLEC6 is measured. Determine whether SIGLEC6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of SIGLEC6 is measured. Determine whether SIGLEC6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3346
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of RP11-390B4.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of RP11-390B4.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4837
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in KCTD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in KCTD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1375
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in ZNF429 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in ZNF429 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of SIGLEC6. Does this perturbation cause a significant change in SIGLEC6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of SIGLEC6. Does this perturbation cause a significant change in SIGLEC6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3344
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of RP11-212I21.4 is measured. Determine whether RP11-212I21.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of RP11-212I21.4 is measured. Determine whether RP11-212I21.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2036
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of RILPL2 is measured. Determine whether RILPL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of RILPL2 is measured. Determine whether RILPL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2806
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in RP11-242O24.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in RP11-242O24.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3995
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of NFAT5 is measured. Does this perturbation cause a significant change in NFAT5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of NFAT5 is measured. Does this perturbation cause a significant change in NFAT5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1810
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and MTPN expression is quantified. Does this perturbation result in a significant change in MTPN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and MTPN expression is quantified. Does this perturbation result in a significant change in MTPN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4732
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of SMIM14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of SMIM14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3307
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and GUSB expression is measured. Determine whether GUSB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and GUSB expression is measured. Determine whether GUSB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1409
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and ARHGAP11A expression is quantified. Does this perturbation result in a significant change in ARHGAP11A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and ARHGAP11A expression is quantified. Does this perturbation result in a significant change in ARHGAP11A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3722
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and NFE2L3 expression is quantified. Does this perturbation result in a significant change in NFE2L3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and NFE2L3 expression is quantified. Does this perturbation result in a significant change in NFE2L3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1582
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and NOSTRIN expression is quantified. Does this perturbation result in a significant change in NOSTRIN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and NOSTRIN expression is quantified. Does this perturbation result in a significant change in NOSTRIN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4322
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of HIST1H1D is measured. Does this perturbation cause a significant change in HIST1H1D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of HIST1H1D is measured. Does this perturbation cause a significant change in HIST1H1D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4340
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of PIK3R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of PIK3R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5107
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of OBSCN. Does perturbing HYOU1 lead to a significant change in OBSCN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of OBSCN. Does perturbing HYOU1 lead to a significant change in OBSCN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3821
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor MYH7B expression. Decide whether this perturbation leads to a significant alteration in MYH7B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor MYH7B expression. Decide whether this perturbation leads to a significant alteration in MYH7B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":588
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of SNHG10 is measured. Determine whether SNHG10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of SNHG10 is measured. Determine whether SNHG10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1886
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and RP11-95O2.5 expression is quantified. Does this perturbation result in a significant change in RP11-95O2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and RP11-95O2.5 expression is quantified. Does this perturbation result in a significant change in RP11-95O2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4472
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of HAGH is measured. Determine whether HAGH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of HAGH is measured. Determine whether HAGH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2636
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in IRF7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in IRF7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":535
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and DUT expression is observed. Does this perturbation lead to a significant difference in DUT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and DUT expression is observed. Does this perturbation lead to a significant difference in DUT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":273
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and DNTTIP2 expression is observed. Does this perturbation lead to a significant difference in DNTTIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and DNTTIP2 expression is observed. Does this perturbation lead to a significant difference in DNTTIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":813
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of SKIL. Does this perturbation cause a significant change in SKIL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of SKIL. Does this perturbation cause a significant change in SKIL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2944
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and CFH expression is quantified. Does this perturbation result in a significant change in CFH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and CFH expression is quantified. Does this perturbation result in a significant change in CFH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5052
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and CENPC expression is measured. Determine whether CENPC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and CENPC expression is measured. Determine whether CENPC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4459
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and RNF19A expression is observed. Does this perturbation lead to a significant difference in RNF19A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and RNF19A expression is observed. Does this perturbation lead to a significant difference in RNF19A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3763
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and IRF7 expression is measured. Determine whether IRF7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and IRF7 expression is measured. Determine whether IRF7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":539
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3969
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and RTN2 expression is observed. Does this perturbation lead to a significant difference in RTN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and RTN2 expression is observed. Does this perturbation lead to a significant difference in RTN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2063
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of PAK1IP1 is measured. Determine whether PAK1IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of PAK1IP1 is measured. Determine whether PAK1IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4256
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and TFPI expression is measured. Determine whether TFPI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and TFPI expression is measured. Determine whether TFPI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3919
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and MANF expression is observed. Does this perturbation lead to a significant difference in MANF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and MANF expression is observed. Does this perturbation lead to a significant difference in MANF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2073
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and ANKRD11 expression is quantified. Does this perturbation result in a significant change in ANKRD11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and ANKRD11 expression is quantified. Does this perturbation result in a significant change in ANKRD11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4692
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and ROCK1 expression is quantified. Does this perturbation result in a significant change in ROCK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and ROCK1 expression is quantified. Does this perturbation result in a significant change in ROCK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5152
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and ARHGDIB expression is observed. Does this perturbation lead to a significant difference in ARHGDIB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and ARHGDIB expression is observed. Does this perturbation lead to a significant difference in ARHGDIB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1963
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in RSL24D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in RSL24D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":875
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and DOK3 expression is quantified. Does this perturbation result in a significant change in DOK3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and DOK3 expression is quantified. Does this perturbation result in a significant change in DOK3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":262
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and DDX6 expression is measured. Determine whether DDX6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and DDX6 expression is measured. Determine whether DDX6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":529
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of SPINK5 is measured. Determine whether SPINK5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of SPINK5 is measured. Determine whether SPINK5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":416
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4754
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and SLC26A1 expression is observed. Does this perturbation lead to a significant difference in SLC26A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and SLC26A1 expression is observed. Does this perturbation lead to a significant difference in SLC26A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2193
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of CASP8 is measured. Determine whether CASP8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of CASP8 is measured. Determine whether CASP8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":226
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and BAMBI expression is quantified. Does this perturbation result in a significant change in BAMBI expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and BAMBI expression is quantified. Does this perturbation result in a significant change in BAMBI expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1272
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and TACC3 expression is measured. Determine whether TACC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and TACC3 expression is measured. Determine whether TACC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1869
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of CDK13 is measured. Determine whether CDK13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of CDK13 is measured. Determine whether CDK13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2766
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of RP11-789C1.1 is measured. Does this perturbation cause a significant change in RP11-789C1.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of RP11-789C1.1 is measured. Does this perturbation cause a significant change in RP11-789C1.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":940
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and VIM-AS1 expression is measured. Determine whether VIM-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and VIM-AS1 expression is measured. Determine whether VIM-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1729
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of BRWD3 is measured. Does this perturbation cause a significant change in BRWD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of BRWD3 is measured. Does this perturbation cause a significant change in BRWD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":730
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and MS4A6E expression is measured. Determine whether MS4A6E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and MS4A6E expression is measured. Determine whether MS4A6E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":349
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3963
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of CDKN2C is measured. Does this perturbation cause a significant change in CDKN2C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of CDKN2C is measured. Does this perturbation cause a significant change in CDKN2C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2810
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and GATA2 expression is observed. Does this perturbation lead to a significant difference in GATA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and GATA2 expression is observed. Does this perturbation lead to a significant difference in GATA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5113
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and GSN expression is quantified. Does this perturbation result in a significant change in GSN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and GSN expression is quantified. Does this perturbation result in a significant change in GSN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3202
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of GUSB. Does perturbing TMEM167A lead to a significant change in GUSB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of GUSB. Does perturbing TMEM167A lead to a significant change in GUSB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1931
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of GNPTG is measured. Determine whether GNPTG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of GNPTG is measured. Determine whether GNPTG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3096
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and PSORS1C1 expression is quantified. Does this perturbation result in a significant change in PSORS1C1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and PSORS1C1 expression is quantified. Does this perturbation result in a significant change in PSORS1C1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2272
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2097
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and MANF expression is quantified. Does this perturbation result in a significant change in MANF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and MANF expression is quantified. Does this perturbation result in a significant change in MANF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2072
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RIOK3 expression is quantified. Does this perturbation result in a significant change in RIOK3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RIOK3 expression is quantified. Does this perturbation result in a significant change in RIOK3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and CD58 expression is measured. Determine whether CD58 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and CD58 expression is measured. Determine whether CD58 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2499
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of IL13RA1. Does this perturbation cause a significant change in IL13RA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of IL13RA1. Does this perturbation cause a significant change in IL13RA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2354
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of RP11-138C9.1. Does perturbing TIMM23 lead to a significant change in RP11-138C9.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of RP11-138C9.1. Does perturbing TIMM23 lead to a significant change in RP11-138C9.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":831
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of SKIL is measured. Does this perturbation cause a significant change in SKIL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of SKIL is measured. Does this perturbation cause a significant change in SKIL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2940
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of AKAP11. Does this perturbation cause a significant change in AKAP11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of AKAP11. Does this perturbation cause a significant change in AKAP11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1924
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of LPAR5 is measured. Does this perturbation cause a significant change in LPAR5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of LPAR5 is measured. Does this perturbation cause a significant change in LPAR5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of HM13. Does perturbing DHDDS lead to a significant change in HM13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of HM13. Does perturbing DHDDS lead to a significant change in HM13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4511
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and HIST1H2BC expression is quantified. Does this perturbation result in a significant change in HIST1H2BC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and HIST1H2BC expression is quantified. Does this perturbation result in a significant change in HIST1H2BC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4772
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of CTSV is measured. Determine whether CTSV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of CTSV is measured. Determine whether CTSV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2676
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in KIAA1731 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in KIAA1731 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4895
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and SLFNL1 expression is measured. Determine whether SLFNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and SLFNL1 expression is measured. Determine whether SLFNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":459
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of REST. Does this perturbation cause a significant change in REST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of REST. Does this perturbation cause a significant change in REST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":794
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of PHF21A is measured. Does this perturbation cause a significant change in PHF21A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of PHF21A is measured. Does this perturbation cause a significant change in PHF21A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3850
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of HIST1H2AM. Does this perturbation cause a significant change in HIST1H2AM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of HIST1H2AM. Does this perturbation cause a significant change in HIST1H2AM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":384
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of EXO1. Does perturbing SEC61B lead to a significant change in EXO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of EXO1. Does perturbing SEC61B lead to a significant change in EXO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2831
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and SLC26A1 expression is quantified. Does this perturbation result in a significant change in SLC26A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and SLC26A1 expression is quantified. Does this perturbation result in a significant change in SLC26A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2192
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of GS1-166A23.1. Does perturbing HSPA5 lead to a significant change in GS1-166A23.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of GS1-166A23.1. Does perturbing HSPA5 lead to a significant change in GS1-166A23.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3291
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in IL32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in IL32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":565
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in KIF4A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in KIF4A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2585
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of KLF3. Does perturbing GNPNAT1 lead to a significant change in KLF3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of KLF3. Does perturbing GNPNAT1 lead to a significant change in KLF3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1981
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2739
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of TOB2 is measured. Does this perturbation cause a significant change in TOB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of TOB2 is measured. Does this perturbation cause a significant change in TOB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":980
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and ANKLE2 expression is measured. Determine whether ANKLE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and ANKLE2 expression is measured. Determine whether ANKLE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2319
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2308
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and PLA2G15 expression is measured. Determine whether PLA2G15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and PLA2G15 expression is measured. Determine whether PLA2G15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3839
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of DUSP21 is measured. Does this perturbation cause a significant change in DUSP21 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of DUSP21 is measured. Does this perturbation cause a significant change in DUSP21 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2740
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of FYTTD1 is measured. Determine whether FYTTD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of FYTTD1 is measured. Determine whether FYTTD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2366
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of APOL4. Does perturbing AMIGO3 lead to a significant change in APOL4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of APOL4. Does perturbing AMIGO3 lead to a significant change in APOL4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":891
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of RP11-304M2.5. Does this perturbation cause a significant change in RP11-304M2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of RP11-304M2.5. Does this perturbation cause a significant change in RP11-304M2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4534
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and S100A11 expression is observed. Does this perturbation lead to a significant difference in S100A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and S100A11 expression is observed. Does this perturbation lead to a significant difference in S100A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4643
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in RP11-838N2.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in RP11-838N2.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3035
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of ZEB2. Does this perturbation cause a significant change in ZEB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of ZEB2. Does this perturbation cause a significant change in ZEB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":964
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and ATP11B expression is measured. Determine whether ATP11B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and ATP11B expression is measured. Determine whether ATP11B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":299
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and NUF2 expression is quantified. Does this perturbation result in a significant change in NUF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and NUF2 expression is quantified. Does this perturbation result in a significant change in NUF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1392
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and TSNAXIP1 expression is measured. Determine whether TSNAXIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and TSNAXIP1 expression is measured. Determine whether TSNAXIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":759
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of RP11-3D4.3 is measured. Determine whether RP11-3D4.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of RP11-3D4.3 is measured. Determine whether RP11-3D4.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3646
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of GPRC5C is measured. Determine whether GPRC5C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of GPRC5C is measured. Determine whether GPRC5C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2226
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and SLBP expression is measured. Determine whether SLBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and SLBP expression is measured. Determine whether SLBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2139
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of RP11-24F11.2 is measured. Determine whether RP11-24F11.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of RP11-24F11.2 is measured. Determine whether RP11-24F11.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1496
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor DOCK8 expression. Decide whether this perturbation leads to a significant alteration in DOCK8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor DOCK8 expression. Decide whether this perturbation leads to a significant alteration in DOCK8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1568
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of ACRV1 is measured. Does this perturbation cause a significant change in ACRV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of ACRV1 is measured. Does this perturbation cause a significant change in ACRV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3890
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of BACH2 is measured. Determine whether BACH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of BACH2 is measured. Determine whether BACH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3476
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of SPAST. Does this perturbation cause a significant change in SPAST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of SPAST. Does this perturbation cause a significant change in SPAST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2844
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ROBO1 expression. Decide whether this perturbation leads to a significant alteration in ROBO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ROBO1 expression. Decide whether this perturbation leads to a significant alteration in ROBO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3948
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of GDF11. Does this perturbation cause a significant change in GDF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of GDF11. Does this perturbation cause a significant change in GDF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":394
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of ASPM. Does this perturbation cause a significant change in ASPM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of ASPM. Does this perturbation cause a significant change in ASPM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2664
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and SNHG10 expression is quantified. Does this perturbation result in a significant change in SNHG10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and SNHG10 expression is quantified. Does this perturbation result in a significant change in SNHG10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1312
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of RP11-90P5.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of RP11-90P5.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":407
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in PPP1R16B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in PPP1R16B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4485
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in CELF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in CELF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5035
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of LDLR is measured. Does this perturbation cause a significant change in LDLR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of LDLR is measured. Does this perturbation cause a significant change in LDLR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":490
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of RP11-328J2.1 is measured. Determine whether RP11-328J2.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of RP11-328J2.1 is measured. Determine whether RP11-328J2.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1096
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor AC018878.3 expression. Decide whether this perturbation leads to a significant alteration in AC018878.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor AC018878.3 expression. Decide whether this perturbation leads to a significant alteration in AC018878.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3288
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and CTCFL expression is measured. Determine whether CTCFL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and CTCFL expression is measured. Determine whether CTCFL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2609
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of KLK1. Does this perturbation cause a significant change in KLK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of KLK1. Does this perturbation cause a significant change in KLK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":204
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of NCKAP1L. Does perturbing SRPR lead to a significant change in NCKAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of NCKAP1L. Does perturbing SRPR lead to a significant change in NCKAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":441
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and RSL24D1 expression is observed. Does this perturbation lead to a significant difference in RSL24D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and RSL24D1 expression is observed. Does this perturbation lead to a significant difference in RSL24D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":873
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in KLF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in KLF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2295
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor ATAD2B expression. Decide whether this perturbation leads to a significant alteration in ATAD2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor ATAD2B expression. Decide whether this perturbation leads to a significant alteration in ATAD2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4398
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of ZNF429 is measured. Does this perturbation cause a significant change in ZNF429 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of ZNF429 is measured. Does this perturbation cause a significant change in ZNF429 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":0
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor POU2F2 expression. Decide whether this perturbation leads to a significant alteration in POU2F2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor POU2F2 expression. Decide whether this perturbation leads to a significant alteration in POU2F2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":658
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and AC015987.2 expression is quantified. Does this perturbation result in a significant change in AC015987.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and AC015987.2 expression is quantified. Does this perturbation result in a significant change in AC015987.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2012
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of HIST1H2BC. Does this perturbation cause a significant change in HIST1H2BC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of HIST1H2BC. Does this perturbation cause a significant change in HIST1H2BC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4774
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of IL2RB. Does perturbing EIF2S1 lead to a significant change in IL2RB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of IL2RB. Does perturbing EIF2S1 lead to a significant change in IL2RB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3601
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor DOCK11 expression. Decide whether this perturbation leads to a significant alteration in DOCK11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor DOCK11 expression. Decide whether this perturbation leads to a significant alteration in DOCK11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":368
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and PHF21A expression is measured. Determine whether PHF21A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and PHF21A expression is measured. Determine whether PHF21A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3859
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and ZNF292 expression is observed. Does this perturbation lead to a significant difference in ZNF292 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and ZNF292 expression is observed. Does this perturbation lead to a significant difference in ZNF292 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3563
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of VIM-AS1. Does this perturbation cause a significant change in VIM-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of VIM-AS1. Does this perturbation cause a significant change in VIM-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1724
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of UFD1L is measured. Does this perturbation cause a significant change in UFD1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of UFD1L is measured. Does this perturbation cause a significant change in UFD1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2500
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of HMGCS1 is measured. Does this perturbation cause a significant change in HMGCS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of HMGCS1 is measured. Does this perturbation cause a significant change in HMGCS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":370
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of RP11-242O24.5 is measured. Does this perturbation cause a significant change in RP11-242O24.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of RP11-242O24.5 is measured. Does this perturbation cause a significant change in RP11-242O24.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3990
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in QSER1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in QSER1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4685
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and HIST1H2BC expression is observed. Does this perturbation lead to a significant difference in HIST1H2BC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and HIST1H2BC expression is observed. Does this perturbation lead to a significant difference in HIST1H2BC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4773
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of MTPN. Does perturbing SEC61G lead to a significant change in MTPN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of MTPN. Does perturbing SEC61G lead to a significant change in MTPN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4731
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of TTC32. Does perturbing TTI1 lead to a significant change in TTC32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of TTC32. Does perturbing TTI1 lead to a significant change in TTC32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3211
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and MORC2-AS1 expression is observed. Does this perturbation lead to a significant difference in MORC2-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and MORC2-AS1 expression is observed. Does this perturbation lead to a significant difference in MORC2-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2553
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of TLN1 is measured. Determine whether TLN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of TLN1 is measured. Determine whether TLN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1036
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and LRRC4B expression is measured. Determine whether LRRC4B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and LRRC4B expression is measured. Determine whether LRRC4B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2179
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and NRIP1 expression is quantified. Does this perturbation result in a significant change in NRIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and NRIP1 expression is quantified. Does this perturbation result in a significant change in NRIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of PCF11. Does this perturbation cause a significant change in PCF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of PCF11. Does this perturbation cause a significant change in PCF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5064
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of JARID2. Does perturbing DDRGK1 lead to a significant change in JARID2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of JARID2. Does perturbing DDRGK1 lead to a significant change in JARID2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1211
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of DKFZP779L1853 is measured. Determine whether DKFZP779L1853 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of DKFZP779L1853 is measured. Determine whether DKFZP779L1853 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2386
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of IRF7 is measured. Determine whether IRF7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of IRF7 is measured. Determine whether IRF7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":536
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor ACE expression. Decide whether this perturbation leads to a significant alteration in ACE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor ACE expression. Decide whether this perturbation leads to a significant alteration in ACE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2578
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and CDCA3 expression is measured. Determine whether CDCA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and CDCA3 expression is measured. Determine whether CDCA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4119
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in NXF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in NXF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3115
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and TSPAN33 expression is measured. Determine whether TSPAN33 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and TSPAN33 expression is measured. Determine whether TSPAN33 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3529
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of DNMBP. Does perturbing TMED10 lead to a significant change in DNMBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of DNMBP. Does perturbing TMED10 lead to a significant change in DNMBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4011
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of VPS41. Does perturbing HARS lead to a significant change in VPS41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of VPS41. Does perturbing HARS lead to a significant change in VPS41 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":631
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in CTD-2267D19.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in CTD-2267D19.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1545
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of GALNT7 is measured. Determine whether GALNT7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of GALNT7 is measured. Determine whether GALNT7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4386
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of FAM212A. Does perturbing NEDD8 lead to a significant change in FAM212A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of FAM212A. Does perturbing NEDD8 lead to a significant change in FAM212A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2231
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of SLC25A35 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of SLC25A35 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3157
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of RSAD2 is measured. Determine whether RSAD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of RSAD2 is measured. Determine whether RSAD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1466
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1959
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and RP11-138C9.1 expression is measured. Determine whether RP11-138C9.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and RP11-138C9.1 expression is measured. Determine whether RP11-138C9.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":839
  }
]