,question,answer,question_new
4463,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and NAV1 expression is observed. Does this perturbation lead to a significant difference in NAV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and NAV1 expression is observed. Does this perturbation lead to a significant difference in NAV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of ATP6V1B2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of ATP6V1B2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of RP13-216E22.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of RP13-216E22.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of RGS3. Does this perturbation cause a significant change in RGS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of RGS3. Does this perturbation cause a significant change in RGS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and STK17B expression is measured. Determine whether STK17B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and STK17B expression is measured. Determine whether STK17B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1198,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor RP11-435O5.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-435O5.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor RP11-435O5.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-435O5.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
713,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and FAM114A1 expression is observed. Does this perturbation lead to a significant difference in FAM114A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and FAM114A1 expression is observed. Does this perturbation lead to a significant difference in FAM114A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in PKDCC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in PKDCC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in IDS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in IDS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3570,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of APOBEC3D is measured. Does this perturbation cause a significant change in APOBEC3D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of APOBEC3D is measured. Does this perturbation cause a significant change in APOBEC3D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of TOPBP1 is measured. Determine whether TOPBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of TOPBP1 is measured. Determine whether TOPBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in KCNJ13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in KCNJ13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in NFE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in NFE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PHF19. Does perturbing SARS lead to a significant change in PHF19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PHF19. Does perturbing SARS lead to a significant change in PHF19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of UHRF1BP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of UHRF1BP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1308,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor ITGB2 expression. Decide whether this perturbation leads to a significant alteration in ITGB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor ITGB2 expression. Decide whether this perturbation leads to a significant alteration in ITGB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of TGOLN2. Does perturbing SPCS3 lead to a significant change in TGOLN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of TGOLN2. Does perturbing SPCS3 lead to a significant change in TGOLN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
223,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and CASP8 expression is observed. Does this perturbation lead to a significant difference in CASP8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and CASP8 expression is observed. Does this perturbation lead to a significant difference in CASP8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of ERV3-1. Does this perturbation cause a significant change in ERV3-1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of ERV3-1. Does this perturbation cause a significant change in ERV3-1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of HAGH. Does perturbing SEC63 lead to a significant change in HAGH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of HAGH. Does perturbing SEC63 lead to a significant change in HAGH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in ATAD2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in ATAD2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in BAMBI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in BAMBI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ZFP36L2 is measured. Determine whether ZFP36L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ZFP36L2 is measured. Determine whether ZFP36L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in VIM-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in VIM-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
310,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of ANKRD11. Does this perturbation cause a significant change in ANKRD11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of ANKRD11. Does this perturbation cause a significant change in ANKRD11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of TROAP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of TROAP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and SNRNP25 expression is measured. Determine whether SNRNP25 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and SNRNP25 expression is measured. Determine whether SNRNP25 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5040,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of LAMP2 is measured. Does this perturbation cause a significant change in LAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of LAMP2 is measured. Does this perturbation cause a significant change in LAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of YTHDF2. Does this perturbation cause a significant change in YTHDF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of YTHDF2. Does this perturbation cause a significant change in YTHDF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of CRNDE. Does this perturbation cause a significant change in CRNDE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of CRNDE. Does this perturbation cause a significant change in CRNDE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of CTD-2267D19.3. Does perturbing SEL1L lead to a significant change in CTD-2267D19.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of CTD-2267D19.3. Does perturbing SEL1L lead to a significant change in CTD-2267D19.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1863,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and TACC3 expression is observed. Does this perturbation lead to a significant difference in TACC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and TACC3 expression is observed. Does this perturbation lead to a significant difference in TACC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of NBEAL2. Does perturbing ZNF326 lead to a significant change in NBEAL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of NBEAL2. Does perturbing ZNF326 lead to a significant change in NBEAL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3078,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PIF1 expression. Decide whether this perturbation leads to a significant alteration in PIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PIF1 expression. Decide whether this perturbation leads to a significant alteration in PIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3970,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of SEC23IP is measured. Does this perturbation cause a significant change in SEC23IP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of SEC23IP is measured. Does this perturbation cause a significant change in SEC23IP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of EPS15 is measured. Determine whether EPS15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of EPS15 is measured. Determine whether EPS15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5110,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of GATA2 is measured. Does this perturbation cause a significant change in GATA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of GATA2 is measured. Does this perturbation cause a significant change in GATA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ROBO1. Does perturbing SLC35B1 lead to a significant change in ROBO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ROBO1. Does perturbing SLC35B1 lead to a significant change in ROBO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and RP11-390B4.5 expression is quantified. Does this perturbation result in a significant change in RP11-390B4.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and RP11-390B4.5 expression is quantified. Does this perturbation result in a significant change in RP11-390B4.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4700,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of LTB is measured. Does this perturbation cause a significant change in LTB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of LTB is measured. Does this perturbation cause a significant change in LTB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in TIPARP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in TIPARP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in KCNQ1OT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in KCNQ1OT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of SETX. Does this perturbation cause a significant change in SETX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of SETX. Does this perturbation cause a significant change in SETX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in ACRV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in ACRV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of PLA2G15 is measured. Determine whether PLA2G15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of PLA2G15 is measured. Determine whether PLA2G15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3108,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PSMD14 expression. Decide whether this perturbation leads to a significant alteration in PSMD14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PSMD14 expression. Decide whether this perturbation leads to a significant alteration in PSMD14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
38,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor CASP4 expression. Decide whether this perturbation leads to a significant alteration in CASP4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor CASP4 expression. Decide whether this perturbation leads to a significant alteration in CASP4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of RP13-216E22.4 is measured. Determine whether RP13-216E22.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of RP13-216E22.4 is measured. Determine whether RP13-216E22.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and MS4A6E expression is quantified. Does this perturbation result in a significant change in MS4A6E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and MS4A6E expression is quantified. Does this perturbation result in a significant change in MS4A6E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4623,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and KCNQ1OT1 expression is observed. Does this perturbation lead to a significant difference in KCNQ1OT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and KCNQ1OT1 expression is observed. Does this perturbation lead to a significant difference in KCNQ1OT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in ZMYND8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in ZMYND8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and CLINT1 expression is measured. Determine whether CLINT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and CLINT1 expression is measured. Determine whether CLINT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of ZNF292. Does this perturbation cause a significant change in ZNF292 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of ZNF292. Does this perturbation cause a significant change in ZNF292 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in PTGS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in PTGS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of KIAA1731. Does this perturbation cause a significant change in KIAA1731 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of KIAA1731. Does this perturbation cause a significant change in KIAA1731 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of HLA-AS1 is measured. Determine whether HLA-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of HLA-AS1 is measured. Determine whether HLA-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3520,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of TSPAN33 is measured. Does this perturbation cause a significant change in TSPAN33 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of TSPAN33 is measured. Does this perturbation cause a significant change in TSPAN33 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in LTBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in LTBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of LDLR is measured. Determine whether LDLR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of LDLR is measured. Determine whether LDLR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and TRIM38 expression is measured. Determine whether TRIM38 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and TRIM38 expression is measured. Determine whether TRIM38 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and RP11-81A22.5 expression is quantified. Does this perturbation result in a significant change in RP11-81A22.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and RP11-81A22.5 expression is quantified. Does this perturbation result in a significant change in RP11-81A22.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in ANPEP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in ANPEP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1753,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and ARHGAP6 expression is observed. Does this perturbation lead to a significant difference in ARHGAP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and ARHGAP6 expression is observed. Does this perturbation lead to a significant difference in ARHGAP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4168,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor SSBP2 expression. Decide whether this perturbation leads to a significant alteration in SSBP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor SSBP2 expression. Decide whether this perturbation leads to a significant alteration in SSBP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of AMOTL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of AMOTL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and C17orf64 expression is quantified. Does this perturbation result in a significant change in C17orf64 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and C17orf64 expression is quantified. Does this perturbation result in a significant change in C17orf64 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of PDRG1. Does this perturbation cause a significant change in PDRG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of PDRG1. Does this perturbation cause a significant change in PDRG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of HP1BP3. Does this perturbation cause a significant change in HP1BP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of HP1BP3. Does this perturbation cause a significant change in HP1BP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
760,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of HLA-AS1 is measured. Does this perturbation cause a significant change in HLA-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of HLA-AS1 is measured. Does this perturbation cause a significant change in HLA-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of USP34 is measured. Determine whether USP34 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of USP34 is measured. Determine whether USP34 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2758,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RP11-685N10.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-685N10.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RP11-685N10.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-685N10.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and CD9 expression is quantified. Does this perturbation result in a significant change in CD9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and CD9 expression is quantified. Does this perturbation result in a significant change in CD9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of ESCO1 is measured. Determine whether ESCO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of ESCO1 is measured. Determine whether ESCO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1478,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor ARHGAP30 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP30 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor ARHGAP30 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP30 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and MORF4L2 expression is quantified. Does this perturbation result in a significant change in MORF4L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and MORF4L2 expression is quantified. Does this perturbation result in a significant change in MORF4L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of RP11-363D14.1 is measured. Determine whether RP11-363D14.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of RP11-363D14.1 is measured. Determine whether RP11-363D14.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2958,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor ATP5EP2 expression. Decide whether this perturbation leads to a significant alteration in ATP5EP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor ATP5EP2 expression. Decide whether this perturbation leads to a significant alteration in ATP5EP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of POLR2J3 is measured. Determine whether POLR2J3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of POLR2J3 is measured. Determine whether POLR2J3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and RP11-132A1.4 expression is quantified. Does this perturbation result in a significant change in RP11-132A1.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and RP11-132A1.4 expression is quantified. Does this perturbation result in a significant change in RP11-132A1.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in ZNF678 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in ZNF678 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and MT2A expression is measured. Determine whether MT2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and MT2A expression is measured. Determine whether MT2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of RGS20. Does perturbing TMED2 lead to a significant change in RGS20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of RGS20. Does perturbing TMED2 lead to a significant change in RGS20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4883,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and WARS expression is observed. Does this perturbation lead to a significant difference in WARS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and WARS expression is observed. Does this perturbation lead to a significant difference in WARS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of RP11-423O2.5. Does perturbing SEC61A1 lead to a significant change in RP11-423O2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of RP11-423O2.5. Does perturbing SEC61A1 lead to a significant change in RP11-423O2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in AC096559.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in AC096559.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1763,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and C12orf23 expression is observed. Does this perturbation lead to a significant difference in C12orf23 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and C12orf23 expression is observed. Does this perturbation lead to a significant difference in C12orf23 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of TET1 is measured. Determine whether TET1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of TET1 is measured. Determine whether TET1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2173,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and LRRC4B expression is observed. Does this perturbation lead to a significant difference in LRRC4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and LRRC4B expression is observed. Does this perturbation lead to a significant difference in LRRC4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in IL13RA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in IL13RA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ROBO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ROBO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and SPAST expression is quantified. Does this perturbation result in a significant change in SPAST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and SPAST expression is quantified. Does this perturbation result in a significant change in SPAST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and RNF8 expression is quantified. Does this perturbation result in a significant change in RNF8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and RNF8 expression is quantified. Does this perturbation result in a significant change in RNF8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of DNMBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of DNMBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and PGM3 expression is quantified. Does this perturbation result in a significant change in PGM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and PGM3 expression is quantified. Does this perturbation result in a significant change in PGM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of SPAST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of SPAST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of C3AR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of C3AR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4148,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor RILPL2 expression. Decide whether this perturbation leads to a significant alteration in RILPL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor RILPL2 expression. Decide whether this perturbation leads to a significant alteration in RILPL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of RAD51AP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of RAD51AP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1578,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor SPEN expression. Decide whether this perturbation leads to a significant alteration in SPEN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor SPEN expression. Decide whether this perturbation leads to a significant alteration in SPEN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and GATA3 expression is quantified. Does this perturbation result in a significant change in GATA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and GATA3 expression is quantified. Does this perturbation result in a significant change in GATA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of HRK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of HRK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of PBDC1. Does perturbing HARS lead to a significant change in PBDC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of PBDC1. Does perturbing HARS lead to a significant change in PBDC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and CLDN11 expression is measured. Determine whether CLDN11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and CLDN11 expression is measured. Determine whether CLDN11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of PAK1IP1. Does perturbing CHERP lead to a significant change in PAK1IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of PAK1IP1. Does perturbing CHERP lead to a significant change in PAK1IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and NOX5 expression is quantified. Does this perturbation result in a significant change in NOX5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and NOX5 expression is quantified. Does this perturbation result in a significant change in NOX5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of GATA2. Does this perturbation cause a significant change in GATA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of GATA2. Does this perturbation cause a significant change in GATA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and UHRF1BP1L expression is measured. Determine whether UHRF1BP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and UHRF1BP1L expression is measured. Determine whether UHRF1BP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and TMEM60 expression is quantified. Does this perturbation result in a significant change in TMEM60 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and TMEM60 expression is quantified. Does this perturbation result in a significant change in TMEM60 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4753,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and CENPF expression is quantified. Does this perturbation result in a significant change in CENPF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and CENPF expression is quantified. Does this perturbation result in a significant change in CENPF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of MLEC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of MLEC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3280,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of AC018878.3 is measured. Does this perturbation cause a significant change in AC018878.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of AC018878.3 is measured. Does this perturbation cause a significant change in AC018878.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in TKTL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in TKTL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of SBF2. Does this perturbation cause a significant change in SBF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of SBF2. Does this perturbation cause a significant change in SBF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of RILPL2 is measured. Determine whether RILPL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of RILPL2 is measured. Determine whether RILPL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and HLA-E expression is measured. Determine whether HLA-E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and HLA-E expression is measured. Determine whether HLA-E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of IL18R1. Does perturbing SEC61A1 lead to a significant change in IL18R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of IL18R1. Does perturbing SEC61A1 lead to a significant change in IL18R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of ACSM3. Does perturbing DERL2 lead to a significant change in ACSM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of ACSM3. Does perturbing DERL2 lead to a significant change in ACSM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3968,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and PCK2 expression is measured. Determine whether PCK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and PCK2 expression is measured. Determine whether PCK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4710,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of TAP1 is measured. Does this perturbation cause a significant change in TAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of TAP1 is measured. Does this perturbation cause a significant change in TAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of CDK13. Does perturbing HSD17B12 lead to a significant change in CDK13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of CDK13. Does perturbing HSD17B12 lead to a significant change in CDK13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
61,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RIOK3. Does perturbing ZNF326 lead to a significant change in RIOK3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RIOK3. Does perturbing ZNF326 lead to a significant change in RIOK3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of GMEB1. Does perturbing DDRGK1 lead to a significant change in GMEB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of GMEB1. Does perturbing DDRGK1 lead to a significant change in GMEB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of DUT. Does perturbing OST4 lead to a significant change in DUT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of DUT. Does perturbing OST4 lead to a significant change in DUT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
430,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of CLINT1 is measured. Does this perturbation cause a significant change in CLINT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of CLINT1 is measured. Does this perturbation cause a significant change in CLINT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and ZNF280B expression is quantified. Does this perturbation result in a significant change in ZNF280B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and ZNF280B expression is quantified. Does this perturbation result in a significant change in ZNF280B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of MANF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of MANF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1980,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of KLF3 is measured. Does this perturbation cause a significant change in KLF3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of KLF3 is measured. Does this perturbation cause a significant change in KLF3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
633,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and VPS41 expression is observed. Does this perturbation lead to a significant difference in VPS41 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and VPS41 expression is observed. Does this perturbation lead to a significant difference in VPS41 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of GLG1. Does this perturbation cause a significant change in GLG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of GLG1. Does this perturbation cause a significant change in GLG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in RNF139-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in RNF139-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of IDH3A is measured. Determine whether IDH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of IDH3A is measured. Determine whether IDH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of APOBEC3D. Does perturbing SRP68 lead to a significant change in APOBEC3D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of APOBEC3D. Does perturbing SRP68 lead to a significant change in APOBEC3D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4260,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of RASGRP2 is measured. Does this perturbation cause a significant change in RASGRP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of RASGRP2 is measured. Does this perturbation cause a significant change in RASGRP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
110,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RP11-65L19.4 is measured. Does this perturbation cause a significant change in RP11-65L19.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RP11-65L19.4 is measured. Does this perturbation cause a significant change in RP11-65L19.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of PSMC1 is measured. Determine whether PSMC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of PSMC1 is measured. Determine whether PSMC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of CTCFL is measured. Determine whether CTCFL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of CTCFL is measured. Determine whether CTCFL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1743,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and RPL39 expression is observed. Does this perturbation lead to a significant difference in RPL39 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and RPL39 expression is observed. Does this perturbation lead to a significant difference in RPL39 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
150,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of CTSF is measured. Does this perturbation cause a significant change in CTSF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of CTSF is measured. Does this perturbation cause a significant change in CTSF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of GATA2 is measured. Determine whether GATA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of GATA2 is measured. Determine whether GATA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ZXDA expression is quantified. Does this perturbation result in a significant change in ZXDA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ZXDA expression is quantified. Does this perturbation result in a significant change in ZXDA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3413,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and NOX5 expression is observed. Does this perturbation lead to a significant difference in NOX5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and NOX5 expression is observed. Does this perturbation lead to a significant difference in NOX5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of RP11-212I21.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of RP11-212I21.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of RP11-334C17.5. Does perturbing IDH3A lead to a significant change in RP11-334C17.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of RP11-334C17.5. Does perturbing IDH3A lead to a significant change in RP11-334C17.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and BACH2 expression is measured. Determine whether BACH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and BACH2 expression is measured. Determine whether BACH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of MANF. Does perturbing TTI2 lead to a significant change in MANF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of MANF. Does perturbing TTI2 lead to a significant change in MANF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of LINC01031 is measured. Determine whether LINC01031 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of LINC01031 is measured. Determine whether LINC01031 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1320,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of NPDC1 is measured. Does this perturbation cause a significant change in NPDC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of NPDC1 is measured. Does this perturbation cause a significant change in NPDC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4748,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor PAXBP1 expression. Decide whether this perturbation leads to a significant alteration in PAXBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor PAXBP1 expression. Decide whether this perturbation leads to a significant alteration in PAXBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
478,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor RP11-146D12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-146D12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor RP11-146D12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-146D12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2378,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor PPP4R2 expression. Decide whether this perturbation leads to a significant alteration in PPP4R2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor PPP4R2 expression. Decide whether this perturbation leads to a significant alteration in PPP4R2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and LDLR expression is measured. Determine whether LDLR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and LDLR expression is measured. Determine whether LDLR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of EP300 is measured. Determine whether EP300 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of EP300 is measured. Determine whether EP300 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2910,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of AFF1 is measured. Does this perturbation cause a significant change in AFF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of AFF1 is measured. Does this perturbation cause a significant change in AFF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1688,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor EP300 expression. Decide whether this perturbation leads to a significant alteration in EP300 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor EP300 expression. Decide whether this perturbation leads to a significant alteration in EP300 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1790,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of PKDCC is measured. Does this perturbation cause a significant change in PKDCC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of PKDCC is measured. Does this perturbation cause a significant change in PKDCC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ARHGAP6. Does perturbing SLC35B1 lead to a significant change in ARHGAP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ARHGAP6. Does perturbing SLC35B1 lead to a significant change in ARHGAP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of ZCCHC11. Does this perturbation cause a significant change in ZCCHC11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of ZCCHC11. Does this perturbation cause a significant change in ZCCHC11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1098,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor RP11-328J2.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-328J2.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor RP11-328J2.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-328J2.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of ATP6V1B2. Does this perturbation cause a significant change in ATP6V1B2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of ATP6V1B2. Does this perturbation cause a significant change in ATP6V1B2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3843,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and TRPM4 expression is observed. Does this perturbation lead to a significant difference in TRPM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and TRPM4 expression is observed. Does this perturbation lead to a significant difference in TRPM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of TRIM24. Does this perturbation cause a significant change in TRIM24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of TRIM24. Does this perturbation cause a significant change in TRIM24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of CTD-2587M2.1. Does this perturbation cause a significant change in CTD-2587M2.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of CTD-2587M2.1. Does this perturbation cause a significant change in CTD-2587M2.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in ATF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in ATF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4068,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor CENPF expression. Decide whether this perturbation leads to a significant alteration in CENPF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor CENPF expression. Decide whether this perturbation leads to a significant alteration in CENPF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of AC096559.1 is measured. Determine whether AC096559.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of AC096559.1 is measured. Determine whether AC096559.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of DYNC1H1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of DYNC1H1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1103,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and ZNF280B expression is observed. Does this perturbation lead to a significant difference in ZNF280B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and ZNF280B expression is observed. Does this perturbation lead to a significant difference in ZNF280B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ARHGAP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ARHGAP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and SETD5-AS1 expression is measured. Determine whether SETD5-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and SETD5-AS1 expression is measured. Determine whether SETD5-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and MTPN expression is measured. Determine whether MTPN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and MTPN expression is measured. Determine whether MTPN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of CDRT4. Does perturbing OST4 lead to a significant change in CDRT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of CDRT4. Does perturbing OST4 lead to a significant change in CDRT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of NOX5 is measured. Determine whether NOX5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of NOX5 is measured. Determine whether NOX5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and SSBP2 expression is measured. Determine whether SSBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and SSBP2 expression is measured. Determine whether SSBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4090,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of DSC2 is measured. Does this perturbation cause a significant change in DSC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of DSC2 is measured. Does this perturbation cause a significant change in DSC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in TRIM38 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in TRIM38 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1800,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of LTBP1 is measured. Does this perturbation cause a significant change in LTBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of LTBP1 is measured. Does this perturbation cause a significant change in LTBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of ZNF341 is measured. Determine whether ZNF341 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of ZNF341 is measured. Determine whether ZNF341 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in HIST1H3D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in HIST1H3D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in AC079466.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in AC079466.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of TMOD3. Does this perturbation cause a significant change in TMOD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of TMOD3. Does this perturbation cause a significant change in TMOD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and DOCK8 expression is measured. Determine whether DOCK8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and DOCK8 expression is measured. Determine whether DOCK8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of LTB. Does this perturbation cause a significant change in LTB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of LTB. Does this perturbation cause a significant change in LTB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of RP11-640M9.1. Does perturbing SOCS1 lead to a significant change in RP11-640M9.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of RP11-640M9.1. Does perturbing SOCS1 lead to a significant change in RP11-640M9.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1393,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and NUF2 expression is observed. Does this perturbation lead to a significant difference in NUF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and NUF2 expression is observed. Does this perturbation lead to a significant difference in NUF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of PCK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of PCK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of RSAD2. Does perturbing FECH lead to a significant change in RSAD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of RSAD2. Does perturbing FECH lead to a significant change in RSAD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in RP11-640M9.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in RP11-640M9.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of RP11-157D23.2 is measured. Determine whether RP11-157D23.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of RP11-157D23.2 is measured. Determine whether RP11-157D23.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of TGOLN2. Does this perturbation cause a significant change in TGOLN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of TGOLN2. Does this perturbation cause a significant change in TGOLN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
570,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of CTD-2001C12.1 is measured. Does this perturbation cause a significant change in CTD-2001C12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of CTD-2001C12.1 is measured. Does this perturbation cause a significant change in CTD-2001C12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of HLTF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of HLTF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of CHD3. Does perturbing CARS lead to a significant change in CHD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of CHD3. Does perturbing CARS lead to a significant change in CHD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in GRN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in GRN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of EP400 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of EP400 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of SHOX2 is measured. Determine whether SHOX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of SHOX2 is measured. Determine whether SHOX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
750,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of TSNAXIP1 is measured. Does this perturbation cause a significant change in TSNAXIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of TSNAXIP1 is measured. Does this perturbation cause a significant change in TSNAXIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4203,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and IL18R1 expression is observed. Does this perturbation lead to a significant difference in IL18R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and IL18R1 expression is observed. Does this perturbation lead to a significant difference in IL18R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1020,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of HIST1H1E is measured. Does this perturbation cause a significant change in HIST1H1E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of HIST1H1E is measured. Does this perturbation cause a significant change in HIST1H1E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of SRP72 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of SRP72 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of C6orf120 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of C6orf120 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of IFT27. Does perturbing CHERP lead to a significant change in IFT27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of IFT27. Does perturbing CHERP lead to a significant change in IFT27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of IFNGR1 is measured. Determine whether IFNGR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of IFNGR1 is measured. Determine whether IFNGR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3920,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of PPM1N is measured. Does this perturbation cause a significant change in PPM1N expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of PPM1N is measured. Does this perturbation cause a significant change in PPM1N expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of ABI2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of ABI2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in VIMP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in VIMP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of IL2RB is measured. Determine whether IL2RB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of IL2RB is measured. Determine whether IL2RB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4083,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and SPEN expression is observed. Does this perturbation lead to a significant difference in SPEN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and SPEN expression is observed. Does this perturbation lead to a significant difference in SPEN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and SNHG7 expression is measured. Determine whether SNHG7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and SNHG7 expression is measured. Determine whether SNHG7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2900,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of VAMP2 is measured. Does this perturbation cause a significant change in VAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of VAMP2 is measured. Does this perturbation cause a significant change in VAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ROBO1 expression is quantified. Does this perturbation result in a significant change in ROBO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ROBO1 expression is quantified. Does this perturbation result in a significant change in ROBO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of AC018878.3. Does this perturbation cause a significant change in AC018878.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of AC018878.3. Does this perturbation cause a significant change in AC018878.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of RP11-434H6.6 is measured. Determine whether RP11-434H6.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of RP11-434H6.6 is measured. Determine whether RP11-434H6.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2188,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor CENPC expression. Decide whether this perturbation leads to a significant alteration in CENPC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor CENPC expression. Decide whether this perturbation leads to a significant alteration in CENPC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3743,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and KIAA0922 expression is observed. Does this perturbation lead to a significant difference in KIAA0922 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and KIAA0922 expression is observed. Does this perturbation lead to a significant difference in KIAA0922 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in EP300 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in EP300 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3898,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor ACRV1 expression. Decide whether this perturbation leads to a significant alteration in ACRV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor ACRV1 expression. Decide whether this perturbation leads to a significant alteration in ACRV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and LTN1 expression is quantified. Does this perturbation result in a significant change in LTN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and LTN1 expression is quantified. Does this perturbation result in a significant change in LTN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3003,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and QSER1 expression is observed. Does this perturbation lead to a significant difference in QSER1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and QSER1 expression is observed. Does this perturbation lead to a significant difference in QSER1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of IFT27. Does this perturbation cause a significant change in IFT27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of IFT27. Does this perturbation cause a significant change in IFT27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
460,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of ERV3-1 is measured. Does this perturbation cause a significant change in ERV3-1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of ERV3-1 is measured. Does this perturbation cause a significant change in ERV3-1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of DNASE2 is measured. Determine whether DNASE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of DNASE2 is measured. Determine whether DNASE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in RILPL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in RILPL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1780,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of KCNH7 is measured. Does this perturbation cause a significant change in KCNH7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of KCNH7 is measured. Does this perturbation cause a significant change in KCNH7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3998,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor RP11-242O24.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-242O24.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor RP11-242O24.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-242O24.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of ASPM. Does perturbing MANF lead to a significant change in ASPM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of ASPM. Does perturbing MANF lead to a significant change in ASPM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1518,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor TMOD3 expression. Decide whether this perturbation leads to a significant alteration in TMOD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor TMOD3 expression. Decide whether this perturbation leads to a significant alteration in TMOD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and KLF3 expression is quantified. Does this perturbation result in a significant change in KLF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and KLF3 expression is quantified. Does this perturbation result in a significant change in KLF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2928,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor AC007038.7 expression. Decide whether this perturbation leads to a significant alteration in AC007038.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor AC007038.7 expression. Decide whether this perturbation leads to a significant alteration in AC007038.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and CRNDE expression is quantified. Does this perturbation result in a significant change in CRNDE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and CRNDE expression is quantified. Does this perturbation result in a significant change in CRNDE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3450,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ZFP36L2 is measured. Does this perturbation cause a significant change in ZFP36L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ZFP36L2 is measured. Does this perturbation cause a significant change in ZFP36L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2993,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and CTD-2521M24.9 expression is observed. Does this perturbation lead to a significant difference in CTD-2521M24.9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and CTD-2521M24.9 expression is observed. Does this perturbation lead to a significant difference in CTD-2521M24.9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of RP11-242O24.5 is measured. Determine whether RP11-242O24.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of RP11-242O24.5 is measured. Determine whether RP11-242O24.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of LTN1. Does perturbing ARHGAP22 lead to a significant change in LTN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of LTN1. Does perturbing ARHGAP22 lead to a significant change in LTN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3473,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and BACH2 expression is observed. Does this perturbation lead to a significant difference in BACH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and BACH2 expression is observed. Does this perturbation lead to a significant difference in BACH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of FAM212A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of FAM212A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of C12orf23 is measured. Determine whether C12orf23 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of C12orf23 is measured. Determine whether C12orf23 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in HLTF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in HLTF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2803,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and RILPL2 expression is observed. Does this perturbation lead to a significant difference in RILPL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and RILPL2 expression is observed. Does this perturbation lead to a significant difference in RILPL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of HIST1H1D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of HIST1H1D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of LIMS1. Does perturbing SRP72 lead to a significant change in LIMS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of LIMS1. Does perturbing SRP72 lead to a significant change in LIMS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3118,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor NXF1 expression. Decide whether this perturbation leads to a significant alteration in NXF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor NXF1 expression. Decide whether this perturbation leads to a significant alteration in NXF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in TET1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in TET1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of ZMYND8. Does this perturbation cause a significant change in ZMYND8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of ZMYND8. Does this perturbation cause a significant change in ZMYND8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and RP11-863K10.7 expression is quantified. Does this perturbation result in a significant change in RP11-863K10.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and RP11-863K10.7 expression is quantified. Does this perturbation result in a significant change in RP11-863K10.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4670,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of H1FX is measured. Does this perturbation cause a significant change in H1FX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of H1FX is measured. Does this perturbation cause a significant change in H1FX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of WARS. Does perturbing CARS lead to a significant change in WARS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of WARS. Does perturbing CARS lead to a significant change in WARS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and NPDC1 expression is measured. Determine whether NPDC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and NPDC1 expression is measured. Determine whether NPDC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4740,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of PAXBP1 is measured. Does this perturbation cause a significant change in PAXBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of PAXBP1 is measured. Does this perturbation cause a significant change in PAXBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and RP11-61E11.1 expression is quantified. Does this perturbation result in a significant change in RP11-61E11.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and RP11-61E11.1 expression is quantified. Does this perturbation result in a significant change in RP11-61E11.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in TTC18 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in TTC18 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3778,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor ZNF341 expression. Decide whether this perturbation leads to a significant alteration in ZNF341 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor ZNF341 expression. Decide whether this perturbation leads to a significant alteration in ZNF341 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and TFPI expression is quantified. Does this perturbation result in a significant change in TFPI expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and TFPI expression is quantified. Does this perturbation result in a significant change in TFPI expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of ANKLE2. Does perturbing TELO2 lead to a significant change in ANKLE2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of ANKLE2. Does perturbing TELO2 lead to a significant change in ANKLE2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1443,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and AC079466.1 expression is observed. Does this perturbation lead to a significant difference in AC079466.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and AC079466.1 expression is observed. Does this perturbation lead to a significant difference in AC079466.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in AC015987.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in AC015987.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and RP11-254F7.4 expression is measured. Determine whether RP11-254F7.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and RP11-254F7.4 expression is measured. Determine whether RP11-254F7.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and ERV3-1 expression is quantified. Does this perturbation result in a significant change in ERV3-1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and ERV3-1 expression is quantified. Does this perturbation result in a significant change in ERV3-1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of RPL39. Does perturbing MTHFD1 lead to a significant change in RPL39 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of RPL39. Does perturbing MTHFD1 lead to a significant change in RPL39 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2700,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RAI14 is measured. Does this perturbation cause a significant change in RAI14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RAI14 is measured. Does this perturbation cause a significant change in RAI14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of S100A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of S100A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of MS4A6E is measured. Determine whether MS4A6E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of MS4A6E is measured. Determine whether MS4A6E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
53,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and C6orf48 expression is observed. Does this perturbation lead to a significant difference in C6orf48 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and C6orf48 expression is observed. Does this perturbation lead to a significant difference in C6orf48 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of NAV2 is measured. Determine whether NAV2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of NAV2 is measured. Determine whether NAV2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of NUF2. Does perturbing SAMM50 lead to a significant change in NUF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of NUF2. Does perturbing SAMM50 lead to a significant change in NUF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and RP11-445H22.3 expression is quantified. Does this perturbation result in a significant change in RP11-445H22.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and RP11-445H22.3 expression is quantified. Does this perturbation result in a significant change in RP11-445H22.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of TSNAXIP1. Does perturbing DAD1 lead to a significant change in TSNAXIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of TSNAXIP1. Does perturbing DAD1 lead to a significant change in TSNAXIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in RP11-573D15.9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in RP11-573D15.9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and RP3-465N24.6 expression is measured. Determine whether RP3-465N24.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and RP3-465N24.6 expression is measured. Determine whether RP3-465N24.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of PHLDA2. Does perturbing COPZ1 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of PHLDA2. Does perturbing COPZ1 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2460,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of NUFIP2 is measured. Does this perturbation cause a significant change in NUFIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of NUFIP2 is measured. Does this perturbation cause a significant change in NUFIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
603,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and PBDC1 expression is observed. Does this perturbation lead to a significant difference in PBDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and PBDC1 expression is observed. Does this perturbation lead to a significant difference in PBDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3753,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and KIAA1432 expression is observed. Does this perturbation lead to a significant difference in KIAA1432 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and KIAA1432 expression is observed. Does this perturbation lead to a significant difference in KIAA1432 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
870,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of RSL24D1 is measured. Does this perturbation cause a significant change in RSL24D1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of RSL24D1 is measured. Does this perturbation cause a significant change in RSL24D1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of SPAST. Does this perturbation cause a significant change in SPAST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of SPAST. Does this perturbation cause a significant change in SPAST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in CST7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in CST7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of AKAP11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of AKAP11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and CDCA3 expression is quantified. Does this perturbation result in a significant change in CDCA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and CDCA3 expression is quantified. Does this perturbation result in a significant change in CDCA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3050,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of RP11-363D14.1 is measured. Does this perturbation cause a significant change in RP11-363D14.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of RP11-363D14.1 is measured. Does this perturbation cause a significant change in RP11-363D14.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
920,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of SPAST is measured. Does this perturbation cause a significant change in SPAST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of SPAST is measured. Does this perturbation cause a significant change in SPAST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of RILPL2. Does this perturbation cause a significant change in RILPL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of RILPL2. Does this perturbation cause a significant change in RILPL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2018,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor AC015987.2 expression. Decide whether this perturbation leads to a significant alteration in AC015987.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor AC015987.2 expression. Decide whether this perturbation leads to a significant alteration in AC015987.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2550,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of MORC2-AS1 is measured. Does this perturbation cause a significant change in MORC2-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of MORC2-AS1 is measured. Does this perturbation cause a significant change in MORC2-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and S100A10 expression is measured. Determine whether S100A10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and S100A10 expression is measured. Determine whether S100A10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in AC012594.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in AC012594.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of SNHG7. Does perturbing CCND3 lead to a significant change in SNHG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of SNHG7. Does perturbing CCND3 lead to a significant change in SNHG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of PKDCC. Does perturbing MTHFD1 lead to a significant change in PKDCC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of PKDCC. Does perturbing MTHFD1 lead to a significant change in PKDCC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
893,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and APOL4 expression is observed. Does this perturbation lead to a significant difference in APOL4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and APOL4 expression is observed. Does this perturbation lead to a significant difference in APOL4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of UHRF1BP1L. Does perturbing OST4 lead to a significant change in UHRF1BP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of UHRF1BP1L. Does perturbing OST4 lead to a significant change in UHRF1BP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of STC2. Does this perturbation cause a significant change in STC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of STC2. Does this perturbation cause a significant change in STC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2913,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and AFF1 expression is observed. Does this perturbation lead to a significant difference in AFF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and AFF1 expression is observed. Does this perturbation lead to a significant difference in AFF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and PHF21A expression is quantified. Does this perturbation result in a significant change in PHF21A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and PHF21A expression is quantified. Does this perturbation result in a significant change in PHF21A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2640,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of IDH3A is measured. Does this perturbation cause a significant change in IDH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of IDH3A is measured. Does this perturbation cause a significant change in IDH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of RILPL2. Does perturbing COPB1 lead to a significant change in RILPL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of RILPL2. Does perturbing COPB1 lead to a significant change in RILPL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of OXLD1. Does this perturbation cause a significant change in OXLD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of OXLD1. Does this perturbation cause a significant change in OXLD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of ARHGDIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of ARHGDIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
930,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of RP11-863K10.7 is measured. Does this perturbation cause a significant change in RP11-863K10.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of RP11-863K10.7 is measured. Does this perturbation cause a significant change in RP11-863K10.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
328,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor LTB expression. Decide whether this perturbation leads to a significant alteration in LTB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor LTB expression. Decide whether this perturbation leads to a significant alteration in LTB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2738,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in CD83 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in CD83 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of TLK2. Does this perturbation cause a significant change in TLK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of TLK2. Does this perturbation cause a significant change in TLK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of ARHGDIB. Does this perturbation cause a significant change in ARHGDIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of ARHGDIB. Does this perturbation cause a significant change in ARHGDIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of ZMYND8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of ZMYND8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of SHOX2. Does perturbing IDH3A lead to a significant change in SHOX2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of SHOX2. Does perturbing IDH3A lead to a significant change in SHOX2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and NRIP1 expression is measured. Determine whether NRIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and NRIP1 expression is measured. Determine whether NRIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of ZNF789. Does this perturbation cause a significant change in ZNF789 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of ZNF789. Does this perturbation cause a significant change in ZNF789 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of LRRC4B. Does this perturbation cause a significant change in LRRC4B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of LRRC4B. Does this perturbation cause a significant change in LRRC4B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of SEC23IP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of SEC23IP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of SRP72. Does perturbing DDRGK1 lead to a significant change in SRP72 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of SRP72. Does perturbing DDRGK1 lead to a significant change in SRP72 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3360,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of SETX is measured. Does this perturbation cause a significant change in SETX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of SETX is measured. Does this perturbation cause a significant change in SETX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and RP11-95O2.5 expression is measured. Determine whether RP11-95O2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and RP11-95O2.5 expression is measured. Determine whether RP11-95O2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
100,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of NBEAL2 is measured. Does this perturbation cause a significant change in NBEAL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of NBEAL2 is measured. Does this perturbation cause a significant change in NBEAL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in EPB42 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in EPB42 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of RP11-15E18.1. Does perturbing CCND3 lead to a significant change in RP11-15E18.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of RP11-15E18.1. Does perturbing CCND3 lead to a significant change in RP11-15E18.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of KIF4A. Does perturbing SEC63 lead to a significant change in KIF4A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of KIF4A. Does perturbing SEC63 lead to a significant change in KIF4A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of S100A11. Does perturbing HSPA5 lead to a significant change in S100A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of S100A11. Does perturbing HSPA5 lead to a significant change in S100A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and LRRC4B expression is quantified. Does this perturbation result in a significant change in LRRC4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and LRRC4B expression is quantified. Does this perturbation result in a significant change in LRRC4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2133,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and SLBP expression is observed. Does this perturbation lead to a significant difference in SLBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and SLBP expression is observed. Does this perturbation lead to a significant difference in SLBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1670,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of AC012594.1 is measured. Does this perturbation cause a significant change in AC012594.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of AC012594.1 is measured. Does this perturbation cause a significant change in AC012594.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2463,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and NUFIP2 expression is observed. Does this perturbation lead to a significant difference in NUFIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and NUFIP2 expression is observed. Does this perturbation lead to a significant difference in NUFIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of DOCK8 is measured. Determine whether DOCK8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of DOCK8 is measured. Determine whether DOCK8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of ZNF280B is measured. Determine whether ZNF280B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of ZNF280B is measured. Determine whether ZNF280B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and TRAPPC10 expression is quantified. Does this perturbation result in a significant change in TRAPPC10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and TRAPPC10 expression is quantified. Does this perturbation result in a significant change in TRAPPC10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2648,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor IDH3A expression. Decide whether this perturbation leads to a significant alteration in IDH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor IDH3A expression. Decide whether this perturbation leads to a significant alteration in IDH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of RSAD2. Does this perturbation cause a significant change in RSAD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of RSAD2. Does this perturbation cause a significant change in RSAD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and TRPM4 expression is quantified. Does this perturbation result in a significant change in TRPM4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and TRPM4 expression is quantified. Does this perturbation result in a significant change in TRPM4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2633,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and HAGH expression is observed. Does this perturbation lead to a significant difference in HAGH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and HAGH expression is observed. Does this perturbation lead to a significant difference in HAGH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in ARSA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in ARSA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and CTC-550B14.7 expression is measured. Determine whether CTC-550B14.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and CTC-550B14.7 expression is measured. Determine whether CTC-550B14.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in PPP1R16B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in PPP1R16B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of H3F3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of H3F3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5033,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and CELF6 expression is observed. Does this perturbation lead to a significant difference in CELF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and CELF6 expression is observed. Does this perturbation lead to a significant difference in CELF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in HIST1H2BC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in HIST1H2BC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and S100A10 expression is quantified. Does this perturbation result in a significant change in S100A10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and S100A10 expression is quantified. Does this perturbation result in a significant change in S100A10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in SDF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in SDF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and AC015987.1 expression is quantified. Does this perturbation result in a significant change in AC015987.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and AC015987.1 expression is quantified. Does this perturbation result in a significant change in AC015987.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of UHMK1. Does perturbing P4HB lead to a significant change in UHMK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of UHMK1. Does perturbing P4HB lead to a significant change in UHMK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and RP11-499F3.2 expression is quantified. Does this perturbation result in a significant change in RP11-499F3.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and RP11-499F3.2 expression is quantified. Does this perturbation result in a significant change in RP11-499F3.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of AC008074.3 is measured. Determine whether AC008074.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of AC008074.3 is measured. Determine whether AC008074.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of NBEAL2. Does this perturbation cause a significant change in NBEAL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of NBEAL2. Does this perturbation cause a significant change in NBEAL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and RP11-445H22.3 expression is measured. Determine whether RP11-445H22.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and RP11-445H22.3 expression is measured. Determine whether RP11-445H22.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1818,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor NFAT5 expression. Decide whether this perturbation leads to a significant alteration in NFAT5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor NFAT5 expression. Decide whether this perturbation leads to a significant alteration in NFAT5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3193,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and TRIM24 expression is observed. Does this perturbation lead to a significant difference in TRIM24 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and TRIM24 expression is observed. Does this perturbation lead to a significant difference in TRIM24 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and RSL24D1 expression is quantified. Does this perturbation result in a significant change in RSL24D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and RSL24D1 expression is quantified. Does this perturbation result in a significant change in RSL24D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of RPL39 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of RPL39 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of NBEAL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of NBEAL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4128,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor FOXO6 expression. Decide whether this perturbation leads to a significant alteration in FOXO6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor FOXO6 expression. Decide whether this perturbation leads to a significant alteration in FOXO6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of FOXO6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of FOXO6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in KIAA1586 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in KIAA1586 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of CTBS is measured. Determine whether CTBS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of CTBS is measured. Determine whether CTBS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1043,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and HRK expression is observed. Does this perturbation lead to a significant difference in HRK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and HRK expression is observed. Does this perturbation lead to a significant difference in HRK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of CD46 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of CD46 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1610,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of RP11-81A22.5 is measured. Does this perturbation cause a significant change in RP11-81A22.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of RP11-81A22.5 is measured. Does this perturbation cause a significant change in RP11-81A22.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
85,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in PHF3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in PHF3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and PTAR1 expression is quantified. Does this perturbation result in a significant change in PTAR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and PTAR1 expression is quantified. Does this perturbation result in a significant change in PTAR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in IL2RB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in IL2RB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of MORF4L2. Does this perturbation cause a significant change in MORF4L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of MORF4L2. Does this perturbation cause a significant change in MORF4L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of KCNQ1OT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of KCNQ1OT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and SMIM14 expression is quantified. Does this perturbation result in a significant change in SMIM14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and SMIM14 expression is quantified. Does this perturbation result in a significant change in SMIM14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of POU2F2. Does this perturbation cause a significant change in POU2F2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of POU2F2. Does this perturbation cause a significant change in POU2F2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1573,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and SPEN expression is observed. Does this perturbation lead to a significant difference in SPEN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and SPEN expression is observed. Does this perturbation lead to a significant difference in SPEN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of ZP3 is measured. Determine whether ZP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of ZP3 is measured. Determine whether ZP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of SLC26A1. Does this perturbation cause a significant change in SLC26A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of SLC26A1. Does this perturbation cause a significant change in SLC26A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of SKIL. Does perturbing ASCC3 lead to a significant change in SKIL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of SKIL. Does perturbing ASCC3 lead to a significant change in SKIL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of ANPEP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of ANPEP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
43,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and LPAR5 expression is observed. Does this perturbation lead to a significant difference in LPAR5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and LPAR5 expression is observed. Does this perturbation lead to a significant difference in LPAR5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of RDH10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of RDH10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3643,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and RP11-3D4.3 expression is observed. Does this perturbation lead to a significant difference in RP11-3D4.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and RP11-3D4.3 expression is observed. Does this perturbation lead to a significant difference in RP11-3D4.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1270,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of BAMBI is measured. Does this perturbation cause a significant change in BAMBI expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of BAMBI is measured. Does this perturbation cause a significant change in BAMBI expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4338,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor GRN expression. Decide whether this perturbation leads to a significant alteration in GRN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor GRN expression. Decide whether this perturbation leads to a significant alteration in GRN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3128,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor RGS20 expression. Decide whether this perturbation leads to a significant alteration in RGS20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor RGS20 expression. Decide whether this perturbation leads to a significant alteration in RGS20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of LINC01031. Does perturbing CHERP lead to a significant change in LINC01031 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of LINC01031. Does perturbing CHERP lead to a significant change in LINC01031 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and ZNF280B expression is measured. Determine whether ZNF280B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and ZNF280B expression is measured. Determine whether ZNF280B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in F2RL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in F2RL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of MT2A. Does this perturbation cause a significant change in MT2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of MT2A. Does this perturbation cause a significant change in MT2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of RP11-119J18.1. Does this perturbation cause a significant change in RP11-119J18.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of RP11-119J18.1. Does this perturbation cause a significant change in RP11-119J18.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of TOPBP1. Does this perturbation cause a significant change in TOPBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of TOPBP1. Does this perturbation cause a significant change in TOPBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
863,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and ESCO1 expression is observed. Does this perturbation lead to a significant difference in ESCO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and ESCO1 expression is observed. Does this perturbation lead to a significant difference in ESCO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2393,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and RP11-254F7.4 expression is observed. Does this perturbation lead to a significant difference in RP11-254F7.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and RP11-254F7.4 expression is observed. Does this perturbation lead to a significant difference in RP11-254F7.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of HMGCS1 is measured. Determine whether HMGCS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of HMGCS1 is measured. Determine whether HMGCS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of RCBTB2 is measured. Determine whether RCBTB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of RCBTB2 is measured. Determine whether RCBTB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of JARID2. Does this perturbation cause a significant change in JARID2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of JARID2. Does this perturbation cause a significant change in JARID2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3803,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and TOPBP1 expression is observed. Does this perturbation lead to a significant difference in TOPBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and TOPBP1 expression is observed. Does this perturbation lead to a significant difference in TOPBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3023,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and HIST1H2AC expression is observed. Does this perturbation lead to a significant difference in HIST1H2AC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and HIST1H2AC expression is observed. Does this perturbation lead to a significant difference in HIST1H2AC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of TET1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of TET1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of RP11-119J18.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of RP11-119J18.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and RP11-423O2.5 expression is quantified. Does this perturbation result in a significant change in RP11-423O2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and RP11-423O2.5 expression is quantified. Does this perturbation result in a significant change in RP11-423O2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1643,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and SERPINH1 expression is observed. Does this perturbation lead to a significant difference in SERPINH1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and SERPINH1 expression is observed. Does this perturbation lead to a significant difference in SERPINH1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in GMEB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in GMEB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in NRIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in NRIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2260,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of C6orf120 is measured. Does this perturbation cause a significant change in C6orf120 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of C6orf120 is measured. Does this perturbation cause a significant change in C6orf120 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1380,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of ZEB1 is measured. Does this perturbation cause a significant change in ZEB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of ZEB1 is measured. Does this perturbation cause a significant change in ZEB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in DYNC1H1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in DYNC1H1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1913,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and CTD-2587M2.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2587M2.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and CTD-2587M2.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2587M2.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of NOXA1 is measured. Determine whether NOXA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of NOXA1 is measured. Determine whether NOXA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of LINC00938 is measured. Determine whether LINC00938 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of LINC00938 is measured. Determine whether LINC00938 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
910,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of HIST1H3D is measured. Does this perturbation cause a significant change in HIST1H3D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of HIST1H3D is measured. Does this perturbation cause a significant change in HIST1H3D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of PARP11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of PARP11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of RTN2. Does this perturbation cause a significant change in RTN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of RTN2. Does this perturbation cause a significant change in RTN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of CTD-2267D19.3 is measured. Determine whether CTD-2267D19.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of CTD-2267D19.3 is measured. Determine whether CTD-2267D19.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and SLC37A1 expression is measured. Determine whether SLC37A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and SLC37A1 expression is measured. Determine whether SLC37A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and RP1-274L7.1 expression is quantified. Does this perturbation result in a significant change in RP1-274L7.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and RP1-274L7.1 expression is quantified. Does this perturbation result in a significant change in RP1-274L7.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and ZEB2 expression is measured. Determine whether ZEB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and ZEB2 expression is measured. Determine whether ZEB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1158,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor SLC37A1 expression. Decide whether this perturbation leads to a significant alteration in SLC37A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor SLC37A1 expression. Decide whether this perturbation leads to a significant alteration in SLC37A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of ATP5EP2 is measured. Determine whether ATP5EP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of ATP5EP2 is measured. Determine whether ATP5EP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in SEPT5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in SEPT5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of REST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of REST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PIF1. Does this perturbation cause a significant change in PIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PIF1. Does this perturbation cause a significant change in PIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of RNF139-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of RNF139-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1660,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of RP11-247A12.2 is measured. Does this perturbation cause a significant change in RP11-247A12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of RP11-247A12.2 is measured. Does this perturbation cause a significant change in RP11-247A12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and CFH expression is measured. Determine whether CFH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and CFH expression is measured. Determine whether CFH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3163,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and MT2A expression is observed. Does this perturbation lead to a significant difference in MT2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and MT2A expression is observed. Does this perturbation lead to a significant difference in MT2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of RP11-81A22.5. Does perturbing PDIA6 lead to a significant change in RP11-81A22.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of RP11-81A22.5. Does perturbing PDIA6 lead to a significant change in RP11-81A22.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2818,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor CDKN2C expression. Decide whether this perturbation leads to a significant alteration in CDKN2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor CDKN2C expression. Decide whether this perturbation leads to a significant alteration in CDKN2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in ATF7IP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in ATF7IP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of CCRL2. Does perturbing SRP68 lead to a significant change in CCRL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of CCRL2. Does perturbing SRP68 lead to a significant change in CCRL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of GCKR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of GCKR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in GSN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in GSN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2723,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of CLDN11. Does perturbing SEC63 lead to a significant change in CLDN11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of CLDN11. Does perturbing SEC63 lead to a significant change in CLDN11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of NINJ2 is measured. Determine whether NINJ2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of NINJ2 is measured. Determine whether NINJ2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1298,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor RP11-573D15.9 expression. Decide whether this perturbation leads to a significant alteration in RP11-573D15.9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor RP11-573D15.9 expression. Decide whether this perturbation leads to a significant alteration in RP11-573D15.9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and APOL4 expression is quantified. Does this perturbation result in a significant change in APOL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and APOL4 expression is quantified. Does this perturbation result in a significant change in APOL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of GS1-166A23.1. Does this perturbation cause a significant change in GS1-166A23.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of GS1-166A23.1. Does this perturbation cause a significant change in GS1-166A23.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in C6orf120 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in C6orf120 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of CASP8. Does this perturbation cause a significant change in CASP8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of CASP8. Does this perturbation cause a significant change in CASP8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of TMEM60 is measured. Determine whether TMEM60 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of TMEM60 is measured. Determine whether TMEM60 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3918,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor TFPI expression. Decide whether this perturbation leads to a significant alteration in TFPI expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor TFPI expression. Decide whether this perturbation leads to a significant alteration in TFPI expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and DSC2 expression is measured. Determine whether DSC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and DSC2 expression is measured. Determine whether DSC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of RP11-146D12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of RP11-146D12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and P4HA2 expression is measured. Determine whether P4HA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and P4HA2 expression is measured. Determine whether P4HA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of NUF2. Does this perturbation cause a significant change in NUF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of NUF2. Does this perturbation cause a significant change in NUF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3270,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of TSC22D4 is measured. Does this perturbation cause a significant change in TSC22D4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of TSC22D4 is measured. Does this perturbation cause a significant change in TSC22D4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and MORF4L2 expression is measured. Determine whether MORF4L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and MORF4L2 expression is measured. Determine whether MORF4L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of CTD-2020K17.1. Does this perturbation cause a significant change in CTD-2020K17.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of CTD-2020K17.1. Does this perturbation cause a significant change in CTD-2020K17.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of OXLD1. Does perturbing SEC61B lead to a significant change in OXLD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of OXLD1. Does perturbing SEC61B lead to a significant change in OXLD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of FCGRT. Does perturbing SCYL1 lead to a significant change in FCGRT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of FCGRT. Does perturbing SCYL1 lead to a significant change in FCGRT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3828,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor OBSCN expression. Decide whether this perturbation leads to a significant alteration in OBSCN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor OBSCN expression. Decide whether this perturbation leads to a significant alteration in OBSCN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in NRIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in NRIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2288,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor TNFRSF10B expression. Decide whether this perturbation leads to a significant alteration in TNFRSF10B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor TNFRSF10B expression. Decide whether this perturbation leads to a significant alteration in TNFRSF10B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and LBX1 expression is quantified. Does this perturbation result in a significant change in LBX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and LBX1 expression is quantified. Does this perturbation result in a significant change in LBX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4323,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and NOSTRIN expression is observed. Does this perturbation lead to a significant difference in NOSTRIN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and NOSTRIN expression is observed. Does this perturbation lead to a significant difference in NOSTRIN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and P4HA2 expression is quantified. Does this perturbation result in a significant change in P4HA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and P4HA2 expression is quantified. Does this perturbation result in a significant change in P4HA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
103,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and NBEAL2 expression is observed. Does this perturbation lead to a significant difference in NBEAL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and NBEAL2 expression is observed. Does this perturbation lead to a significant difference in NBEAL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3458,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ZFP36L2 expression. Decide whether this perturbation leads to a significant alteration in ZFP36L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ZFP36L2 expression. Decide whether this perturbation leads to a significant alteration in ZFP36L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and THBS1 expression is measured. Determine whether THBS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and THBS1 expression is measured. Determine whether THBS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RP11-65L19.4. Does this perturbation cause a significant change in RP11-65L19.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RP11-65L19.4. Does this perturbation cause a significant change in RP11-65L19.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
30,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of CASP4 is measured. Does this perturbation cause a significant change in CASP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of CASP4 is measured. Does this perturbation cause a significant change in CASP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
190,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of PDE9A is measured. Does this perturbation cause a significant change in PDE9A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of PDE9A is measured. Does this perturbation cause a significant change in PDE9A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and CST7 expression is measured. Determine whether CST7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and CST7 expression is measured. Determine whether CST7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2250,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of AC015987.1 is measured. Does this perturbation cause a significant change in AC015987.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of AC015987.1 is measured. Does this perturbation cause a significant change in AC015987.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1648,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor SERPINH1 expression. Decide whether this perturbation leads to a significant alteration in SERPINH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor SERPINH1 expression. Decide whether this perturbation leads to a significant alteration in SERPINH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1710,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of EPB42 is measured. Does this perturbation cause a significant change in EPB42 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of EPB42 is measured. Does this perturbation cause a significant change in EPB42 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
13,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and P4HA2 expression is observed. Does this perturbation lead to a significant difference in P4HA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and P4HA2 expression is observed. Does this perturbation lead to a significant difference in P4HA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4030,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of NTRK1 is measured. Does this perturbation cause a significant change in NTRK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of NTRK1 is measured. Does this perturbation cause a significant change in NTRK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and RP11-119J18.1 expression is quantified. Does this perturbation result in a significant change in RP11-119J18.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and RP11-119J18.1 expression is quantified. Does this perturbation result in a significant change in RP11-119J18.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in ACE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in ACE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and SERPINF2 expression is quantified. Does this perturbation result in a significant change in SERPINF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and SERPINF2 expression is quantified. Does this perturbation result in a significant change in SERPINF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and ANXA4 expression is measured. Determine whether ANXA4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and ANXA4 expression is measured. Determine whether ANXA4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4968,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor EIF4B expression. Decide whether this perturbation leads to a significant alteration in EIF4B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor EIF4B expression. Decide whether this perturbation leads to a significant alteration in EIF4B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of TLK2 is measured. Determine whether TLK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of TLK2 is measured. Determine whether TLK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of SLBP is measured. Determine whether SLBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of SLBP is measured. Determine whether SLBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of RP1-274L7.1 is measured. Determine whether RP1-274L7.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of RP1-274L7.1 is measured. Determine whether RP1-274L7.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and PDE9A expression is quantified. Does this perturbation result in a significant change in PDE9A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and PDE9A expression is quantified. Does this perturbation result in a significant change in PDE9A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of SLFNL1. Does this perturbation cause a significant change in SLFNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of SLFNL1. Does this perturbation cause a significant change in SLFNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of IL18R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of IL18R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3058,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor RP11-363D14.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-363D14.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor RP11-363D14.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-363D14.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in PAXBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in PAXBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of KCTD19 is measured. Determine whether KCTD19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of KCTD19 is measured. Determine whether KCTD19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and SPEN expression is measured. Determine whether SPEN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and SPEN expression is measured. Determine whether SPEN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5100,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of PIK3R1 is measured. Does this perturbation cause a significant change in PIK3R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of PIK3R1 is measured. Does this perturbation cause a significant change in PIK3R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of NPDC1. Does this perturbation cause a significant change in NPDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of NPDC1. Does this perturbation cause a significant change in NPDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of IL2RB. Does perturbing TMED10 lead to a significant change in IL2RB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of IL2RB. Does perturbing TMED10 lead to a significant change in IL2RB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and CTBS expression is quantified. Does this perturbation result in a significant change in CTBS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and CTBS expression is quantified. Does this perturbation result in a significant change in CTBS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in LINC00862 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in LINC00862 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1293,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and RP11-573D15.9 expression is observed. Does this perturbation lead to a significant difference in RP11-573D15.9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and RP11-573D15.9 expression is observed. Does this perturbation lead to a significant difference in RP11-573D15.9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of TSPAN33. Does perturbing SCYL1 lead to a significant change in TSPAN33 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of TSPAN33. Does perturbing SCYL1 lead to a significant change in TSPAN33 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in HIST1H1D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in HIST1H1D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of RP11-322J23.1. Does this perturbation cause a significant change in RP11-322J23.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of RP11-322J23.1. Does this perturbation cause a significant change in RP11-322J23.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of AKAP11 is measured. Determine whether AKAP11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of AKAP11 is measured. Determine whether AKAP11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in GATA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in GATA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4018,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor DNMBP expression. Decide whether this perturbation leads to a significant alteration in DNMBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor DNMBP expression. Decide whether this perturbation leads to a significant alteration in DNMBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and SDF4 expression is measured. Determine whether SDF4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and SDF4 expression is measured. Determine whether SDF4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of CLDN11. Does this perturbation cause a significant change in CLDN11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of CLDN11. Does this perturbation cause a significant change in CLDN11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of TMEM60 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of TMEM60 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and DSC2 expression is quantified. Does this perturbation result in a significant change in DSC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and DSC2 expression is quantified. Does this perturbation result in a significant change in DSC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of MED13 is measured. Determine whether MED13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of MED13 is measured. Determine whether MED13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3198,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor TRIM24 expression. Decide whether this perturbation leads to a significant alteration in TRIM24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor TRIM24 expression. Decide whether this perturbation leads to a significant alteration in TRIM24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4460,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of NAV1 is measured. Does this perturbation cause a significant change in NAV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of NAV1 is measured. Does this perturbation cause a significant change in NAV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of SPEN. Does perturbing PDIA6 lead to a significant change in SPEN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of SPEN. Does perturbing PDIA6 lead to a significant change in SPEN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of CCRL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of CCRL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2843,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and SPAST expression is observed. Does this perturbation lead to a significant difference in SPAST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and SPAST expression is observed. Does this perturbation lead to a significant difference in SPAST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4308,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor GCKR expression. Decide whether this perturbation leads to a significant alteration in GCKR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor GCKR expression. Decide whether this perturbation leads to a significant alteration in GCKR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and NTRK1 expression is measured. Determine whether NTRK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and NTRK1 expression is measured. Determine whether NTRK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of COPB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of COPB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of EP300. Does perturbing TTI2 lead to a significant change in EP300 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of EP300. Does perturbing TTI2 lead to a significant change in EP300 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in NPAT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in NPAT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4193,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and CTD-2020K17.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2020K17.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and CTD-2020K17.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2020K17.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1448,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor AC079466.1 expression. Decide whether this perturbation leads to a significant alteration in AC079466.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor AC079466.1 expression. Decide whether this perturbation leads to a significant alteration in AC079466.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of SLBP. Does this perturbation cause a significant change in SLBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of SLBP. Does this perturbation cause a significant change in SLBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RAI14. Does this perturbation cause a significant change in RAI14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RAI14. Does this perturbation cause a significant change in RAI14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of NFE2L3 is measured. Determine whether NFE2L3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of NFE2L3 is measured. Determine whether NFE2L3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of DOCK11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of DOCK11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1588,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor NFE2L3 expression. Decide whether this perturbation leads to a significant alteration in NFE2L3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor NFE2L3 expression. Decide whether this perturbation leads to a significant alteration in NFE2L3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4683,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and QSER1 expression is observed. Does this perturbation lead to a significant difference in QSER1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and QSER1 expression is observed. Does this perturbation lead to a significant difference in QSER1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3573,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and APOBEC3D expression is observed. Does this perturbation lead to a significant difference in APOBEC3D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and APOBEC3D expression is observed. Does this perturbation lead to a significant difference in APOBEC3D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in CTCFL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in CTCFL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and STARD9 expression is quantified. Does this perturbation result in a significant change in STARD9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and STARD9 expression is quantified. Does this perturbation result in a significant change in STARD9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in TSPAN33 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in TSPAN33 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in TRPM4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in TRPM4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3388,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor TRIM38 expression. Decide whether this perturbation leads to a significant alteration in TRIM38 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor TRIM38 expression. Decide whether this perturbation leads to a significant alteration in TRIM38 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and C12orf44 expression is quantified. Does this perturbation result in a significant change in C12orf44 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and C12orf44 expression is quantified. Does this perturbation result in a significant change in C12orf44 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4908,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor CHD3 expression. Decide whether this perturbation leads to a significant alteration in CHD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor CHD3 expression. Decide whether this perturbation leads to a significant alteration in CHD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of TET1. Does this perturbation cause a significant change in TET1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of TET1. Does this perturbation cause a significant change in TET1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in LIMS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in LIMS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in GNPTG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in GNPTG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in RP13-216E22.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in RP13-216E22.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and PKDCC expression is measured. Determine whether PKDCC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and PKDCC expression is measured. Determine whether PKDCC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in REST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in REST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3073,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PIF1 expression is observed. Does this perturbation lead to a significant difference in PIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PIF1 expression is observed. Does this perturbation lead to a significant difference in PIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
693,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and SPCS2 expression is observed. Does this perturbation lead to a significant difference in SPCS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and SPCS2 expression is observed. Does this perturbation lead to a significant difference in SPCS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1860,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of TACC3 is measured. Does this perturbation cause a significant change in TACC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of TACC3 is measured. Does this perturbation cause a significant change in TACC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of PDRG1 is measured. Determine whether PDRG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of PDRG1 is measured. Determine whether PDRG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of RNF139-AS1. Does perturbing FARSB lead to a significant change in RNF139-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of RNF139-AS1. Does perturbing FARSB lead to a significant change in RNF139-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and ACSM3 expression is quantified. Does this perturbation result in a significant change in ACSM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and ACSM3 expression is quantified. Does this perturbation result in a significant change in ACSM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in KHDC1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in KHDC1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and ARSA expression is quantified. Does this perturbation result in a significant change in ARSA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and ARSA expression is quantified. Does this perturbation result in a significant change in ARSA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of ARHGAP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of ARHGAP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of CDKN2C. Does this perturbation cause a significant change in CDKN2C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of CDKN2C. Does this perturbation cause a significant change in CDKN2C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in HRK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in HRK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1553,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and RP11-381O7.3 expression is observed. Does this perturbation lead to a significant difference in RP11-381O7.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and RP11-381O7.3 expression is observed. Does this perturbation lead to a significant difference in RP11-381O7.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1088,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor DDX3X expression. Decide whether this perturbation leads to a significant alteration in DDX3X expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor DDX3X expression. Decide whether this perturbation leads to a significant alteration in DDX3X expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of WARS is measured. Determine whether WARS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of WARS is measured. Determine whether WARS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and TOB2 expression is quantified. Does this perturbation result in a significant change in TOB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and TOB2 expression is quantified. Does this perturbation result in a significant change in TOB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2718,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RGS20 expression. Decide whether this perturbation leads to a significant alteration in RGS20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RGS20 expression. Decide whether this perturbation leads to a significant alteration in RGS20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3693,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and TTC18 expression is observed. Does this perturbation lead to a significant difference in TTC18 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and TTC18 expression is observed. Does this perturbation lead to a significant difference in TTC18 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and KLF6 expression is quantified. Does this perturbation result in a significant change in KLF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and KLF6 expression is quantified. Does this perturbation result in a significant change in KLF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of NSD1 is measured. Determine whether NSD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of NSD1 is measured. Determine whether NSD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ROBO1 expression is measured. Determine whether ROBO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ROBO1 expression is measured. Determine whether ROBO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in AFF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in AFF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of TTC18 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of TTC18 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of CENPC. Does this perturbation cause a significant change in CENPC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of CENPC. Does this perturbation cause a significant change in CENPC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and DDX3X expression is measured. Determine whether DDX3X exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and DDX3X expression is measured. Determine whether DDX3X exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in THBS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in THBS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of CD46 is measured. Determine whether CD46 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of CD46 is measured. Determine whether CD46 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in SPAST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in SPAST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and NUFIP2 expression is quantified. Does this perturbation result in a significant change in NUFIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and NUFIP2 expression is quantified. Does this perturbation result in a significant change in NUFIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of NOSTRIN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of NOSTRIN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and RDH10 expression is quantified. Does this perturbation result in a significant change in RDH10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and RDH10 expression is quantified. Does this perturbation result in a significant change in RDH10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of C12orf23. Does perturbing MTHFD1 lead to a significant change in C12orf23 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of C12orf23. Does perturbing MTHFD1 lead to a significant change in C12orf23 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2363,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and FYTTD1 expression is observed. Does this perturbation lead to a significant difference in FYTTD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and FYTTD1 expression is observed. Does this perturbation lead to a significant difference in FYTTD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4873,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and S100A10 expression is observed. Does this perturbation lead to a significant difference in S100A10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and S100A10 expression is observed. Does this perturbation lead to a significant difference in S100A10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3283,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and AC018878.3 expression is observed. Does this perturbation lead to a significant difference in AC018878.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and AC018878.3 expression is observed. Does this perturbation lead to a significant difference in AC018878.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2398,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor RP11-254F7.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-254F7.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor RP11-254F7.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-254F7.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of ZC3H7A. Does this perturbation cause a significant change in ZC3H7A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of ZC3H7A. Does this perturbation cause a significant change in ZC3H7A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of USP37. Does this perturbation cause a significant change in USP37 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of USP37. Does this perturbation cause a significant change in USP37 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and EXOC3L2 expression is quantified. Does this perturbation result in a significant change in EXOC3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and EXOC3L2 expression is quantified. Does this perturbation result in a significant change in EXOC3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and ABI2 expression is quantified. Does this perturbation result in a significant change in ABI2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and ABI2 expression is quantified. Does this perturbation result in a significant change in ABI2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and TOPBP1 expression is measured. Determine whether TOPBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and TOPBP1 expression is measured. Determine whether TOPBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
988,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor TOB2 expression. Decide whether this perturbation leads to a significant alteration in TOB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor TOB2 expression. Decide whether this perturbation leads to a significant alteration in TOB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of DSC2. Does this perturbation cause a significant change in DSC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of DSC2. Does this perturbation cause a significant change in DSC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
83,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and PHF3 expression is observed. Does this perturbation lead to a significant difference in PHF3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and PHF3 expression is observed. Does this perturbation lead to a significant difference in PHF3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of RP11-381O7.3 is measured. Determine whether RP11-381O7.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of RP11-381O7.3 is measured. Determine whether RP11-381O7.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of RP11-499F3.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of RP11-499F3.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of S100A11. Does perturbing EIF2B3 lead to a significant change in S100A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of S100A11. Does perturbing EIF2B3 lead to a significant change in S100A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of ATF6 is measured. Determine whether ATF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of ATF6 is measured. Determine whether ATF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in SNHG7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in SNHG7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of NRIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of NRIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2330,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of F2RL2 is measured. Does this perturbation cause a significant change in F2RL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of F2RL2 is measured. Does this perturbation cause a significant change in F2RL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of LRRC4B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of LRRC4B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and RP11-3D4.3 expression is measured. Determine whether RP11-3D4.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and RP11-3D4.3 expression is measured. Determine whether RP11-3D4.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in RP11-61E11.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in RP11-61E11.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of OBSCN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of OBSCN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and DDX3X expression is quantified. Does this perturbation result in a significant change in DDX3X expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and DDX3X expression is quantified. Does this perturbation result in a significant change in DDX3X expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of KIAA1586. Does this perturbation cause a significant change in KIAA1586 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of KIAA1586. Does this perturbation cause a significant change in KIAA1586 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1150,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of SLC37A1 is measured. Does this perturbation cause a significant change in SLC37A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of SLC37A1 is measured. Does this perturbation cause a significant change in SLC37A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1253,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and IL8 expression is observed. Does this perturbation lead to a significant difference in IL8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and IL8 expression is observed. Does this perturbation lead to a significant difference in IL8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of UHMK1 is measured. Determine whether UHMK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of UHMK1 is measured. Determine whether UHMK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and LIMS1 expression is measured. Determine whether LIMS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and LIMS1 expression is measured. Determine whether LIMS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of FGF11. Does this perturbation cause a significant change in FGF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of FGF11. Does this perturbation cause a significant change in FGF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of NFAT5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of NFAT5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of ATXN7L3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of ATXN7L3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and LINC00862 expression is measured. Determine whether LINC00862 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and LINC00862 expression is measured. Determine whether LINC00862 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and BRWD3 expression is measured. Determine whether BRWD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and BRWD3 expression is measured. Determine whether BRWD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1773,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and SDF4 expression is observed. Does this perturbation lead to a significant difference in SDF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and SDF4 expression is observed. Does this perturbation lead to a significant difference in SDF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in KDM1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in KDM1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2028,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor ABI2 expression. Decide whether this perturbation leads to a significant alteration in ABI2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor ABI2 expression. Decide whether this perturbation leads to a significant alteration in ABI2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
240,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of UHRF1BP1L is measured. Does this perturbation cause a significant change in UHRF1BP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of UHRF1BP1L is measured. Does this perturbation cause a significant change in UHRF1BP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RP11-685N10.1 expression is quantified. Does this perturbation result in a significant change in RP11-685N10.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RP11-685N10.1 expression is quantified. Does this perturbation result in a significant change in RP11-685N10.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and JUND expression is quantified. Does this perturbation result in a significant change in JUND expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and JUND expression is quantified. Does this perturbation result in a significant change in JUND expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of ANKLE2 is measured. Determine whether ANKLE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of ANKLE2 is measured. Determine whether ANKLE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of UFD1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of UFD1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of HIST1H1E. Does perturbing IARS2 lead to a significant change in HIST1H1E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of HIST1H1E. Does perturbing IARS2 lead to a significant change in HIST1H1E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1250,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of IL8 is measured. Does this perturbation cause a significant change in IL8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of IL8 is measured. Does this perturbation cause a significant change in IL8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of SPCS2. Does perturbing SLMO2 lead to a significant change in SPCS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of SPCS2. Does perturbing SLMO2 lead to a significant change in SPCS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of RP11-666A20.4. Does perturbing CHERP lead to a significant change in RP11-666A20.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of RP11-666A20.4. Does perturbing CHERP lead to a significant change in RP11-666A20.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1778,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor SDF4 expression. Decide whether this perturbation leads to a significant alteration in SDF4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor SDF4 expression. Decide whether this perturbation leads to a significant alteration in SDF4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in MEX3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in MEX3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4538,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor RP11-304M2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-304M2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor RP11-304M2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-304M2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of NOSTRIN is measured. Determine whether NOSTRIN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of NOSTRIN is measured. Determine whether NOSTRIN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4963,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and EIF4B expression is observed. Does this perturbation lead to a significant difference in EIF4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and EIF4B expression is observed. Does this perturbation lead to a significant difference in EIF4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of PDE4D. Does perturbing IER3IP1 lead to a significant change in PDE4D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of PDE4D. Does perturbing IER3IP1 lead to a significant change in PDE4D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of CLDN11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of CLDN11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
990,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of SHOX2 is measured. Does this perturbation cause a significant change in SHOX2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of SHOX2 is measured. Does this perturbation cause a significant change in SHOX2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and CTD-2587M2.1 expression is quantified. Does this perturbation result in a significant change in CTD-2587M2.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and CTD-2587M2.1 expression is quantified. Does this perturbation result in a significant change in CTD-2587M2.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of PITPNB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of PITPNB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and KCNQ1OT1 expression is quantified. Does this perturbation result in a significant change in KCNQ1OT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and KCNQ1OT1 expression is quantified. Does this perturbation result in a significant change in KCNQ1OT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
530,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of IRF7 is measured. Does this perturbation cause a significant change in IRF7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of IRF7 is measured. Does this perturbation cause a significant change in IRF7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of SLC25A35. Does perturbing ARHGAP22 lead to a significant change in SLC25A35 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of SLC25A35. Does perturbing ARHGAP22 lead to a significant change in SLC25A35 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of KCTD1 is measured. Determine whether KCTD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of KCTD1 is measured. Determine whether KCTD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and SERPING1 expression is measured. Determine whether SERPING1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and SERPING1 expression is measured. Determine whether SERPING1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and RNF139-AS1 expression is quantified. Does this perturbation result in a significant change in RNF139-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and RNF139-AS1 expression is quantified. Does this perturbation result in a significant change in RNF139-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of EXO1 is measured. Determine whether EXO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of EXO1 is measured. Determine whether EXO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of AC104532.4. Does perturbing ASCC3 lead to a significant change in AC104532.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of AC104532.4. Does perturbing ASCC3 lead to a significant change in AC104532.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and GMEB1 expression is measured. Determine whether GMEB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and GMEB1 expression is measured. Determine whether GMEB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and HP1BP3 expression is quantified. Does this perturbation result in a significant change in HP1BP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and HP1BP3 expression is quantified. Does this perturbation result in a significant change in HP1BP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of IL2RB is measured. Determine whether IL2RB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of IL2RB is measured. Determine whether IL2RB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and ZNF429 expression is quantified. Does this perturbation result in a significant change in ZNF429 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and ZNF429 expression is quantified. Does this perturbation result in a significant change in ZNF429 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in SPEN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in SPEN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5053,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and CFH expression is observed. Does this perturbation lead to a significant difference in CFH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and CFH expression is observed. Does this perturbation lead to a significant difference in CFH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of TRPM4. Does perturbing DDOST lead to a significant change in TRPM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of TRPM4. Does perturbing DDOST lead to a significant change in TRPM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3330,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of AP000688.8 is measured. Does this perturbation cause a significant change in AP000688.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of AP000688.8 is measured. Does this perturbation cause a significant change in AP000688.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of CHST12 is measured. Determine whether CHST12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of CHST12 is measured. Determine whether CHST12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of SOBP. Does this perturbation cause a significant change in SOBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of SOBP. Does this perturbation cause a significant change in SOBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of RPL39 is measured. Determine whether RPL39 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of RPL39 is measured. Determine whether RPL39 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of VIM-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of VIM-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of DUSP21 is measured. Determine whether DUSP21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of DUSP21 is measured. Determine whether DUSP21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of AC007038.7. Does perturbing TARS lead to a significant change in AC007038.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of AC007038.7. Does perturbing TARS lead to a significant change in AC007038.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and AC012594.1 expression is measured. Determine whether AC012594.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and AC012594.1 expression is measured. Determine whether AC012594.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in MTPN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in MTPN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
688,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor ARSA expression. Decide whether this perturbation leads to a significant alteration in ARSA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor ARSA expression. Decide whether this perturbation leads to a significant alteration in ARSA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4988,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor UHMK1 expression. Decide whether this perturbation leads to a significant alteration in UHMK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor UHMK1 expression. Decide whether this perturbation leads to a significant alteration in UHMK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of ATAD2B. Does perturbing FECH lead to a significant change in ATAD2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of ATAD2B. Does perturbing FECH lead to a significant change in ATAD2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and JARID2 expression is measured. Determine whether JARID2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and JARID2 expression is measured. Determine whether JARID2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4608,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor STARD9 expression. Decide whether this perturbation leads to a significant alteration in STARD9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor STARD9 expression. Decide whether this perturbation leads to a significant alteration in STARD9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of TSC22D4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of TSC22D4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
338,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor PCK2 expression. Decide whether this perturbation leads to a significant alteration in PCK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor PCK2 expression. Decide whether this perturbation leads to a significant alteration in PCK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of PDE4D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of PDE4D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of ATP11B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of ATP11B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2020,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of ABI2 is measured. Does this perturbation cause a significant change in ABI2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of ABI2 is measured. Does this perturbation cause a significant change in ABI2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of EGLN3. Does this perturbation cause a significant change in EGLN3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of EGLN3. Does this perturbation cause a significant change in EGLN3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of HM13 is measured. Determine whether HM13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of HM13 is measured. Determine whether HM13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of DOCK8. Does this perturbation cause a significant change in DOCK8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of DOCK8. Does this perturbation cause a significant change in DOCK8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PIF1 expression is quantified. Does this perturbation result in a significant change in PIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PIF1 expression is quantified. Does this perturbation result in a significant change in PIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1133,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of LBX1. Does perturbing PDIA6 lead to a significant change in LBX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of LBX1. Does perturbing PDIA6 lead to a significant change in LBX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of PPM1N. Does perturbing SLC35B1 lead to a significant change in PPM1N expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of PPM1N. Does perturbing SLC35B1 lead to a significant change in PPM1N expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
74,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of CEBPG. Does this perturbation cause a significant change in CEBPG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of CEBPG. Does this perturbation cause a significant change in CEBPG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2428,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor HIST1H2AM expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor HIST1H2AM expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in ATP11B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in ATP11B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in DOCK11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in DOCK11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2180,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of CENPC is measured. Does this perturbation cause a significant change in CENPC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of CENPC is measured. Does this perturbation cause a significant change in CENPC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of PARP11. Does this perturbation cause a significant change in PARP11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of PARP11. Does this perturbation cause a significant change in PARP11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of AC007038.7 is measured. Determine whether AC007038.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of AC007038.7 is measured. Determine whether AC007038.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of ANPEP. Does perturbing DNAJC19 lead to a significant change in ANPEP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of ANPEP. Does perturbing DNAJC19 lead to a significant change in ANPEP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of RP11-434H6.6. Does this perturbation cause a significant change in RP11-434H6.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of RP11-434H6.6. Does this perturbation cause a significant change in RP11-434H6.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of CRNDE is measured. Determine whether CRNDE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of CRNDE is measured. Determine whether CRNDE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of RCBTB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of RCBTB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of SBF2 is measured. Determine whether SBF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of SBF2 is measured. Determine whether SBF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
210,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of NFE2 is measured. Does this perturbation cause a significant change in NFE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of NFE2 is measured. Does this perturbation cause a significant change in NFE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of WDR3. Does perturbing COPZ1 lead to a significant change in WDR3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of WDR3. Does perturbing COPZ1 lead to a significant change in WDR3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and KIF4A expression is quantified. Does this perturbation result in a significant change in KIF4A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and KIF4A expression is quantified. Does this perturbation result in a significant change in KIF4A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
520,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of DDX6 is measured. Does this perturbation cause a significant change in DDX6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of DDX6 is measured. Does this perturbation cause a significant change in DDX6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1010,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of KCNE3 is measured. Does this perturbation cause a significant change in KCNE3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of KCNE3 is measured. Does this perturbation cause a significant change in KCNE3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of ANXA4. Does this perturbation cause a significant change in ANXA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of ANXA4. Does this perturbation cause a significant change in ANXA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of ASPM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of ASPM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and CTC-308K20.1 expression is measured. Determine whether CTC-308K20.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and CTC-308K20.1 expression is measured. Determine whether CTC-308K20.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of TLK2. Does perturbing DNAJC19 lead to a significant change in TLK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of TLK2. Does perturbing DNAJC19 lead to a significant change in TLK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of FOXO6. Does this perturbation cause a significant change in FOXO6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of FOXO6. Does this perturbation cause a significant change in FOXO6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4233,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and RP11-666A20.4 expression is observed. Does this perturbation lead to a significant difference in RP11-666A20.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and RP11-666A20.4 expression is observed. Does this perturbation lead to a significant difference in RP11-666A20.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of RGS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of RGS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
543,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and PCF11 expression is observed. Does this perturbation lead to a significant difference in PCF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and PCF11 expression is observed. Does this perturbation lead to a significant difference in PCF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of ANKLE2. Does this perturbation cause a significant change in ANKLE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of ANKLE2. Does this perturbation cause a significant change in ANKLE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
398,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor GDF11 expression. Decide whether this perturbation leads to a significant alteration in GDF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor GDF11 expression. Decide whether this perturbation leads to a significant alteration in GDF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of RP11-254F7.4. Does perturbing HSPA9 lead to a significant change in RP11-254F7.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of RP11-254F7.4. Does perturbing HSPA9 lead to a significant change in RP11-254F7.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
953,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and HERC2 expression is observed. Does this perturbation lead to a significant difference in HERC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and HERC2 expression is observed. Does this perturbation lead to a significant difference in HERC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of QSER1 is measured. Determine whether QSER1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of QSER1 is measured. Determine whether QSER1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1830,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of ATP2A3 is measured. Does this perturbation cause a significant change in ATP2A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of ATP2A3 is measured. Does this perturbation cause a significant change in ATP2A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3428,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ARHGAP6 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ARHGAP6 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of ZNF280B is measured. Determine whether ZNF280B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of ZNF280B is measured. Determine whether ZNF280B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
803,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and COPB1 expression is observed. Does this perturbation lead to a significant difference in COPB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and COPB1 expression is observed. Does this perturbation lead to a significant difference in COPB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2338,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor F2RL2 expression. Decide whether this perturbation leads to a significant alteration in F2RL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor F2RL2 expression. Decide whether this perturbation leads to a significant alteration in F2RL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in EIF3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in EIF3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1438,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor MARCH8 expression. Decide whether this perturbation leads to a significant alteration in MARCH8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor MARCH8 expression. Decide whether this perturbation leads to a significant alteration in MARCH8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and CLDN11 expression is quantified. Does this perturbation result in a significant change in CLDN11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and CLDN11 expression is quantified. Does this perturbation result in a significant change in CLDN11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of TMEM60 is measured. Determine whether TMEM60 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of TMEM60 is measured. Determine whether TMEM60 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4503,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and BIRC5 expression is observed. Does this perturbation lead to a significant difference in BIRC5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and BIRC5 expression is observed. Does this perturbation lead to a significant difference in BIRC5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
278,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor DUT expression. Decide whether this perturbation leads to a significant alteration in DUT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor DUT expression. Decide whether this perturbation leads to a significant alteration in DUT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and RILPL2 expression is quantified. Does this perturbation result in a significant change in RILPL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and RILPL2 expression is quantified. Does this perturbation result in a significant change in RILPL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1143,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and SP100 expression is observed. Does this perturbation lead to a significant difference in SP100 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and SP100 expression is observed. Does this perturbation lead to a significant difference in SP100 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and SMIM14 expression is measured. Determine whether SMIM14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and SMIM14 expression is measured. Determine whether SMIM14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of PDE9A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of PDE9A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2868,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor PIK3IP1 expression. Decide whether this perturbation leads to a significant alteration in PIK3IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor PIK3IP1 expression. Decide whether this perturbation leads to a significant alteration in PIK3IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and RP11-328J2.1 expression is measured. Determine whether RP11-328J2.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and RP11-328J2.1 expression is measured. Determine whether RP11-328J2.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and RP11-157D23.2 expression is measured. Determine whether RP11-157D23.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and RP11-157D23.2 expression is measured. Determine whether RP11-157D23.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of SPAST is measured. Determine whether SPAST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of SPAST is measured. Determine whether SPAST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and NAV2 expression is quantified. Does this perturbation result in a significant change in NAV2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and NAV2 expression is quantified. Does this perturbation result in a significant change in NAV2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and AKAP11 expression is quantified. Does this perturbation result in a significant change in AKAP11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and AKAP11 expression is quantified. Does this perturbation result in a significant change in AKAP11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in ATP6V1B2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in ATP6V1B2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of SEPT5. Does perturbing SRP68 lead to a significant change in SEPT5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of SEPT5. Does perturbing SRP68 lead to a significant change in SEPT5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4343,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and HIST1H1D expression is observed. Does this perturbation lead to a significant difference in HIST1H1D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and HIST1H1D expression is observed. Does this perturbation lead to a significant difference in HIST1H1D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3378,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor LIMS1 expression. Decide whether this perturbation leads to a significant alteration in LIMS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor LIMS1 expression. Decide whether this perturbation leads to a significant alteration in LIMS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3033,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and RP11-838N2.4 expression is observed. Does this perturbation lead to a significant difference in RP11-838N2.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and RP11-838N2.4 expression is observed. Does this perturbation lead to a significant difference in RP11-838N2.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of HIST1H2AC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of HIST1H2AC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in VIM-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in VIM-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in SNRNP25 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in SNRNP25 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and CENPC expression is measured. Determine whether CENPC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and CENPC expression is measured. Determine whether CENPC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of CFH. Does perturbing SPCS3 lead to a significant change in CFH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of CFH. Does perturbing SPCS3 lead to a significant change in CFH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and RP11-435O5.4 expression is measured. Determine whether RP11-435O5.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and RP11-435O5.4 expression is measured. Determine whether RP11-435O5.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
11,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of P4HA2. Does perturbing CREB1 lead to a significant change in P4HA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of P4HA2. Does perturbing CREB1 lead to a significant change in P4HA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and BOLA3 expression is quantified. Does this perturbation result in a significant change in BOLA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and BOLA3 expression is quantified. Does this perturbation result in a significant change in BOLA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and UFD1L expression is quantified. Does this perturbation result in a significant change in UFD1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and UFD1L expression is quantified. Does this perturbation result in a significant change in UFD1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4418,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor AC005540.3 expression. Decide whether this perturbation leads to a significant alteration in AC005540.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor AC005540.3 expression. Decide whether this perturbation leads to a significant alteration in AC005540.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of ATF6. Does this perturbation cause a significant change in ATF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of ATF6. Does this perturbation cause a significant change in ATF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3568,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor ZNF292 expression. Decide whether this perturbation leads to a significant alteration in ZNF292 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor ZNF292 expression. Decide whether this perturbation leads to a significant alteration in ZNF292 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4540,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of CLDN11 is measured. Does this perturbation cause a significant change in CLDN11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of CLDN11 is measured. Does this perturbation cause a significant change in CLDN11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and VAMP2 expression is quantified. Does this perturbation result in a significant change in VAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and VAMP2 expression is quantified. Does this perturbation result in a significant change in VAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PHF19 is measured. Determine whether PHF19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PHF19 is measured. Determine whether PHF19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4693,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and ANKRD11 expression is observed. Does this perturbation lead to a significant difference in ANKRD11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and ANKRD11 expression is observed. Does this perturbation lead to a significant difference in ANKRD11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
878,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor RSL24D1 expression. Decide whether this perturbation leads to a significant alteration in RSL24D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor RSL24D1 expression. Decide whether this perturbation leads to a significant alteration in RSL24D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of EPB42. Does this perturbation cause a significant change in EPB42 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of EPB42. Does this perturbation cause a significant change in EPB42 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2433,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and RP13-216E22.4 expression is observed. Does this perturbation lead to a significant difference in RP13-216E22.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and RP13-216E22.4 expression is observed. Does this perturbation lead to a significant difference in RP13-216E22.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3733,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and PITPNB expression is observed. Does this perturbation lead to a significant difference in PITPNB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and PITPNB expression is observed. Does this perturbation lead to a significant difference in PITPNB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4803,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and EIF3A expression is observed. Does this perturbation lead to a significant difference in EIF3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and EIF3A expression is observed. Does this perturbation lead to a significant difference in EIF3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in EGLN3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in EGLN3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of OXLD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of OXLD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2570,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of ACE is measured. Does this perturbation cause a significant change in ACE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of ACE is measured. Does this perturbation cause a significant change in ACE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ZXDA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ZXDA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and CTNNB1 expression is quantified. Does this perturbation result in a significant change in CTNNB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and CTNNB1 expression is quantified. Does this perturbation result in a significant change in CTNNB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in IDH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in IDH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of ZNF292 is measured. Determine whether ZNF292 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of ZNF292 is measured. Determine whether ZNF292 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1898,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor RP11-434H6.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-434H6.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor RP11-434H6.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-434H6.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3980,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of PELO is measured. Does this perturbation cause a significant change in PELO expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of PELO is measured. Does this perturbation cause a significant change in PELO expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of VIM-AS1. Does perturbing IER3IP1 lead to a significant change in VIM-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of VIM-AS1. Does perturbing IER3IP1 lead to a significant change in VIM-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2950,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of ATP5EP2 is measured. Does this perturbation cause a significant change in ATP5EP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of ATP5EP2 is measured. Does this perturbation cause a significant change in ATP5EP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and DNMBP expression is measured. Determine whether DNMBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and DNMBP expression is measured. Determine whether DNMBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and NFE2 expression is quantified. Does this perturbation result in a significant change in NFE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and NFE2 expression is quantified. Does this perturbation result in a significant change in NFE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
428,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor CD9 expression. Decide whether this perturbation leads to a significant alteration in CD9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor CD9 expression. Decide whether this perturbation leads to a significant alteration in CD9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ROBO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ROBO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of TROAP. Does perturbing SARS lead to a significant change in TROAP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of TROAP. Does perturbing SARS lead to a significant change in TROAP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of VIMP. Does perturbing IDH3A lead to a significant change in VIMP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of VIMP. Does perturbing IDH3A lead to a significant change in VIMP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in DUT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in DUT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of WDR3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of WDR3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of HLA-E. Does this perturbation cause a significant change in HLA-E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of HLA-E. Does this perturbation cause a significant change in HLA-E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1893,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and RP11-434H6.6 expression is observed. Does this perturbation lead to a significant difference in RP11-434H6.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and RP11-434H6.6 expression is observed. Does this perturbation lead to a significant difference in RP11-434H6.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1908,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor AC008074.3 expression. Decide whether this perturbation leads to a significant alteration in AC008074.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor AC008074.3 expression. Decide whether this perturbation leads to a significant alteration in AC008074.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3928,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor PPM1N expression. Decide whether this perturbation leads to a significant alteration in PPM1N expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor PPM1N expression. Decide whether this perturbation leads to a significant alteration in PPM1N expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of IDH3A. Does this perturbation cause a significant change in IDH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of IDH3A. Does this perturbation cause a significant change in IDH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and PAXBP1 expression is quantified. Does this perturbation result in a significant change in PAXBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and PAXBP1 expression is quantified. Does this perturbation result in a significant change in PAXBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and SNHG10 expression is quantified. Does this perturbation result in a significant change in SNHG10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and SNHG10 expression is quantified. Does this perturbation result in a significant change in SNHG10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of KCNE3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of KCNE3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
45,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in LPAR5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in LPAR5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2853,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and OXLD1 expression is observed. Does this perturbation lead to a significant difference in OXLD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and OXLD1 expression is observed. Does this perturbation lead to a significant difference in OXLD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and TRIM24 expression is measured. Determine whether TRIM24 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and TRIM24 expression is measured. Determine whether TRIM24 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1260,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of HOTAIRM1 is measured. Does this perturbation cause a significant change in HOTAIRM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of HOTAIRM1 is measured. Does this perturbation cause a significant change in HOTAIRM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2643,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and IDH3A expression is observed. Does this perturbation lead to a significant difference in IDH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and IDH3A expression is observed. Does this perturbation lead to a significant difference in IDH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3008,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor QSER1 expression. Decide whether this perturbation leads to a significant alteration in QSER1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor QSER1 expression. Decide whether this perturbation leads to a significant alteration in QSER1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in RGS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in RGS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and KANSL1L expression is quantified. Does this perturbation result in a significant change in KANSL1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and KANSL1L expression is quantified. Does this perturbation result in a significant change in KANSL1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and ZEB2 expression is quantified. Does this perturbation result in a significant change in ZEB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and ZEB2 expression is quantified. Does this perturbation result in a significant change in ZEB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3738,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor PITPNB expression. Decide whether this perturbation leads to a significant alteration in PITPNB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor PITPNB expression. Decide whether this perturbation leads to a significant alteration in PITPNB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in COPB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in COPB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of UHMK1. Does this perturbation cause a significant change in UHMK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of UHMK1. Does this perturbation cause a significant change in UHMK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of ERV3-1. Does perturbing SRPR lead to a significant change in ERV3-1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of ERV3-1. Does perturbing SRPR lead to a significant change in ERV3-1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and C10orf32 expression is measured. Determine whether C10orf32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and C10orf32 expression is measured. Determine whether C10orf32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and TAGLN expression is quantified. Does this perturbation result in a significant change in TAGLN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and TAGLN expression is quantified. Does this perturbation result in a significant change in TAGLN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of VIMP. Does perturbing COPZ1 lead to a significant change in VIMP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of VIMP. Does perturbing COPZ1 lead to a significant change in VIMP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and RP11-181G12.2 expression is measured. Determine whether RP11-181G12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and RP11-181G12.2 expression is measured. Determine whether RP11-181G12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of ZNF789. Does perturbing TTI1 lead to a significant change in ZNF789 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of ZNF789. Does perturbing TTI1 lead to a significant change in ZNF789 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of ZNF280B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of ZNF280B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of GRN. Does perturbing SRPRB lead to a significant change in GRN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of GRN. Does perturbing SRPRB lead to a significant change in GRN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of P4HB is measured. Determine whether P4HB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of P4HB is measured. Determine whether P4HB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and OXLD1 expression is measured. Determine whether OXLD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and OXLD1 expression is measured. Determine whether OXLD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1188,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor SETD5-AS1 expression. Decide whether this perturbation leads to a significant alteration in SETD5-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor SETD5-AS1 expression. Decide whether this perturbation leads to a significant alteration in SETD5-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and RP11-640M9.1 expression is measured. Determine whether RP11-640M9.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and RP11-640M9.1 expression is measured. Determine whether RP11-640M9.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3218,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor TTC32 expression. Decide whether this perturbation leads to a significant alteration in TTC32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor TTC32 expression. Decide whether this perturbation leads to a significant alteration in TTC32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of NPDC1. Does perturbing STT3A lead to a significant change in NPDC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of NPDC1. Does perturbing STT3A lead to a significant change in NPDC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in RP11-430H10.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in RP11-430H10.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of CD83. Does perturbing MANF lead to a significant change in CD83 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of CD83. Does perturbing MANF lead to a significant change in CD83 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of S100A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of S100A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of NRIP1 is measured. Determine whether NRIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of NRIP1 is measured. Determine whether NRIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
538,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor IRF7 expression. Decide whether this perturbation leads to a significant alteration in IRF7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor IRF7 expression. Decide whether this perturbation leads to a significant alteration in IRF7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and PRRC2B expression is quantified. Does this perturbation result in a significant change in PRRC2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and PRRC2B expression is quantified. Does this perturbation result in a significant change in PRRC2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2418,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor MANF expression. Decide whether this perturbation leads to a significant alteration in MANF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor MANF expression. Decide whether this perturbation leads to a significant alteration in MANF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of PRRC2B. Does perturbing DARS lead to a significant change in PRRC2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of PRRC2B. Does perturbing DARS lead to a significant change in PRRC2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4820,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of NFE2L3 is measured. Does this perturbation cause a significant change in NFE2L3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of NFE2L3 is measured. Does this perturbation cause a significant change in NFE2L3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2808,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor RILPL2 expression. Decide whether this perturbation leads to a significant alteration in RILPL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor RILPL2 expression. Decide whether this perturbation leads to a significant alteration in RILPL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5083,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and GPR146 expression is observed. Does this perturbation lead to a significant difference in GPR146 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and GPR146 expression is observed. Does this perturbation lead to a significant difference in GPR146 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
91,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RP11-141B14.1. Does perturbing ZNF326 lead to a significant change in RP11-141B14.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RP11-141B14.1. Does perturbing ZNF326 lead to a significant change in RP11-141B14.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in CLDN11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in CLDN11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of EPB42. Does perturbing SYVN1 lead to a significant change in EPB42 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of EPB42. Does perturbing SYVN1 lead to a significant change in EPB42 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and RP11-360L9.8 expression is measured. Determine whether RP11-360L9.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and RP11-360L9.8 expression is measured. Determine whether RP11-360L9.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in PELO expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in PELO expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of RSL24D1. Does perturbing AMIGO3 lead to a significant change in RSL24D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of RSL24D1. Does perturbing AMIGO3 lead to a significant change in RSL24D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and MORC2-AS1 expression is measured. Determine whether MORC2-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and MORC2-AS1 expression is measured. Determine whether MORC2-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2908,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor VAMP2 expression. Decide whether this perturbation leads to a significant alteration in VAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor VAMP2 expression. Decide whether this perturbation leads to a significant alteration in VAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of DST is measured. Determine whether DST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of DST is measured. Determine whether DST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of RP11-138C9.1. Does this perturbation cause a significant change in RP11-138C9.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of RP11-138C9.1. Does this perturbation cause a significant change in RP11-138C9.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in AKAP11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in AKAP11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in LAMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in LAMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and ATAD2B expression is measured. Determine whether ATAD2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and ATAD2B expression is measured. Determine whether ATAD2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of PCK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of PCK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and GCKR expression is measured. Determine whether GCKR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and GCKR expression is measured. Determine whether GCKR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of ATF7IP2. Does perturbing DHDDS lead to a significant change in ATF7IP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of ATF7IP2. Does perturbing DHDDS lead to a significant change in ATF7IP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
900,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of PRRC2B is measured. Does this perturbation cause a significant change in PRRC2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of PRRC2B is measured. Does this perturbation cause a significant change in PRRC2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3098,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor GNPTG expression. Decide whether this perturbation leads to a significant alteration in GNPTG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor GNPTG expression. Decide whether this perturbation leads to a significant alteration in GNPTG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of HIST1H2AM. Does this perturbation cause a significant change in HIST1H2AM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of HIST1H2AM. Does this perturbation cause a significant change in HIST1H2AM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
673,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and MEX3B expression is observed. Does this perturbation lead to a significant difference in MEX3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and MEX3B expression is observed. Does this perturbation lead to a significant difference in MEX3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of PITPNB is measured. Determine whether PITPNB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of PITPNB is measured. Determine whether PITPNB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and DNTTIP2 expression is measured. Determine whether DNTTIP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and DNTTIP2 expression is measured. Determine whether DNTTIP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2310,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of ANKLE2 is measured. Does this perturbation cause a significant change in ANKLE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of ANKLE2 is measured. Does this perturbation cause a significant change in ANKLE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
22,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4430,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of HERPUD1 is measured. Does this perturbation cause a significant change in HERPUD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of HERPUD1 is measured. Does this perturbation cause a significant change in HERPUD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
473,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and RP11-146D12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-146D12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and RP11-146D12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-146D12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2370,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of PPP4R2 is measured. Does this perturbation cause a significant change in PPP4R2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of PPP4R2 is measured. Does this perturbation cause a significant change in PPP4R2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of RIMS3 is measured. Determine whether RIMS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of RIMS3 is measured. Determine whether RIMS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and TSNAXIP1 expression is quantified. Does this perturbation result in a significant change in TSNAXIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and TSNAXIP1 expression is quantified. Does this perturbation result in a significant change in TSNAXIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RP11-685N10.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RP11-685N10.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2548,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor ZP3 expression. Decide whether this perturbation leads to a significant alteration in ZP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor ZP3 expression. Decide whether this perturbation leads to a significant alteration in ZP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
133,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and TET1 expression is observed. Does this perturbation lead to a significant difference in TET1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and TET1 expression is observed. Does this perturbation lead to a significant difference in TET1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of CRYM. Does perturbing FARSB lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of CRYM. Does perturbing FARSB lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and SKIL expression is measured. Determine whether SKIL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and SKIL expression is measured. Determine whether SKIL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of RP11-666A20.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of RP11-666A20.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of ZEB1. Does perturbing SAMM50 lead to a significant change in ZEB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of ZEB1. Does perturbing SAMM50 lead to a significant change in ZEB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and ATP11B expression is quantified. Does this perturbation result in a significant change in ATP11B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and ATP11B expression is quantified. Does this perturbation result in a significant change in ATP11B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of RP11-863K10.7. Does perturbing DARS lead to a significant change in RP11-863K10.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of RP11-863K10.7. Does perturbing DARS lead to a significant change in RP11-863K10.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of VIMP is measured. Determine whether VIMP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of VIMP is measured. Determine whether VIMP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4190,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of CTD-2020K17.1 is measured. Does this perturbation cause a significant change in CTD-2020K17.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of CTD-2020K17.1 is measured. Does this perturbation cause a significant change in CTD-2020K17.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
89,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and PHF3 expression is measured. Determine whether PHF3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and PHF3 expression is measured. Determine whether PHF3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3290,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of GS1-166A23.1 is measured. Does this perturbation cause a significant change in GS1-166A23.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of GS1-166A23.1 is measured. Does this perturbation cause a significant change in GS1-166A23.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and USP37 expression is measured. Determine whether USP37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and USP37 expression is measured. Determine whether USP37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of LINC00657 is measured. Determine whether LINC00657 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of LINC00657 is measured. Determine whether LINC00657 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4493,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and SMCO1 expression is observed. Does this perturbation lead to a significant difference in SMCO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and SMCO1 expression is observed. Does this perturbation lead to a significant difference in SMCO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of TSPAN33 is measured. Determine whether TSPAN33 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of TSPAN33 is measured. Determine whether TSPAN33 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of RP11-304M2.5. Does perturbing DHDDS lead to a significant change in RP11-304M2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of RP11-304M2.5. Does perturbing DHDDS lead to a significant change in RP11-304M2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and ADAMTS10 expression is measured. Determine whether ADAMTS10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and ADAMTS10 expression is measured. Determine whether ADAMTS10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of KLF6. Does perturbing TELO2 lead to a significant change in KLF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of KLF6. Does perturbing TELO2 lead to a significant change in KLF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of LAMP2 is measured. Determine whether LAMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of LAMP2 is measured. Determine whether LAMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of SLC26A1. Does perturbing DERL2 lead to a significant change in SLC26A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of SLC26A1. Does perturbing DERL2 lead to a significant change in SLC26A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
68,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RIOK3 expression. Decide whether this perturbation leads to a significant alteration in RIOK3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RIOK3 expression. Decide whether this perturbation leads to a significant alteration in RIOK3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and CTNNB1 expression is measured. Determine whether CTNNB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and CTNNB1 expression is measured. Determine whether CTNNB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and RP11-381O7.3 expression is measured. Determine whether RP11-381O7.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and RP11-381O7.3 expression is measured. Determine whether RP11-381O7.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in EBI3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in EBI3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in SHOX2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in SHOX2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
79,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and CEBPG expression is measured. Determine whether CEBPG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and CEBPG expression is measured. Determine whether CEBPG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in PSORS1C1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in PSORS1C1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of GSN. Does this perturbation cause a significant change in GSN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of GSN. Does this perturbation cause a significant change in GSN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4658,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor KIAA1586 expression. Decide whether this perturbation leads to a significant alteration in KIAA1586 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor KIAA1586 expression. Decide whether this perturbation leads to a significant alteration in KIAA1586 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and TUBA1C expression is quantified. Does this perturbation result in a significant change in TUBA1C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and TUBA1C expression is quantified. Does this perturbation result in a significant change in TUBA1C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2198,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor SLC26A1 expression. Decide whether this perturbation leads to a significant alteration in SLC26A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor SLC26A1 expression. Decide whether this perturbation leads to a significant alteration in SLC26A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and BRWD3 expression is quantified. Does this perturbation result in a significant change in BRWD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and BRWD3 expression is quantified. Does this perturbation result in a significant change in BRWD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of F2RL2 is measured. Determine whether F2RL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of F2RL2 is measured. Determine whether F2RL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and RP11-119J18.1 expression is measured. Determine whether RP11-119J18.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and RP11-119J18.1 expression is measured. Determine whether RP11-119J18.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of SLC37A1. Does this perturbation cause a significant change in SLC37A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of SLC37A1. Does this perturbation cause a significant change in SLC37A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in RP11-247A12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in RP11-247A12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of ATF7IP2. Does this perturbation cause a significant change in ATF7IP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of ATF7IP2. Does this perturbation cause a significant change in ATF7IP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and FAM114A1 expression is measured. Determine whether FAM114A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and FAM114A1 expression is measured. Determine whether FAM114A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
138,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor TET1 expression. Decide whether this perturbation leads to a significant alteration in TET1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor TET1 expression. Decide whether this perturbation leads to a significant alteration in TET1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of CRNDE. Does perturbing TMEM167A lead to a significant change in CRNDE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of CRNDE. Does perturbing TMEM167A lead to a significant change in CRNDE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of ATP6AP2 is measured. Determine whether ATP6AP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of ATP6AP2 is measured. Determine whether ATP6AP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of RP11-2H8.2. Does perturbing SRP68 lead to a significant change in RP11-2H8.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of RP11-2H8.2. Does perturbing SRP68 lead to a significant change in RP11-2H8.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of SNRNP25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of SNRNP25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of CHD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of CHD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and LTN1 expression is quantified. Does this perturbation result in a significant change in LTN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and LTN1 expression is quantified. Does this perturbation result in a significant change in LTN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of NXF1. Does this perturbation cause a significant change in NXF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of NXF1. Does this perturbation cause a significant change in NXF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in CDT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in CDT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ARHGAP5 expression is quantified. Does this perturbation result in a significant change in ARHGAP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ARHGAP5 expression is quantified. Does this perturbation result in a significant change in ARHGAP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1458,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor LRIF1 expression. Decide whether this perturbation leads to a significant alteration in LRIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor LRIF1 expression. Decide whether this perturbation leads to a significant alteration in LRIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of C9orf64 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of C9orf64 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of ERP29. Does perturbing SPCS3 lead to a significant change in ERP29 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of ERP29. Does perturbing SPCS3 lead to a significant change in ERP29 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of TUBA1C is measured. Determine whether TUBA1C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of TUBA1C is measured. Determine whether TUBA1C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and KCTD1 expression is measured. Determine whether KCTD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and KCTD1 expression is measured. Determine whether KCTD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5048,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor LAMP2 expression. Decide whether this perturbation leads to a significant alteration in LAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor LAMP2 expression. Decide whether this perturbation leads to a significant alteration in LAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and CTC-550B14.7 expression is quantified. Does this perturbation result in a significant change in CTC-550B14.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and CTC-550B14.7 expression is quantified. Does this perturbation result in a significant change in CTC-550B14.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of NUF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of NUF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of KCNQ1OT1. Does perturbing EIF2B3 lead to a significant change in KCNQ1OT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of KCNQ1OT1. Does perturbing EIF2B3 lead to a significant change in KCNQ1OT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in IFNGR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in IFNGR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and F2RL2 expression is measured. Determine whether F2RL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and F2RL2 expression is measured. Determine whether F2RL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of SERPING1 is measured. Determine whether SERPING1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of SERPING1 is measured. Determine whether SERPING1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and MANF expression is measured. Determine whether MANF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and MANF expression is measured. Determine whether MANF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of CELF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of CELF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3608,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor IL2RB expression. Decide whether this perturbation leads to a significant alteration in IL2RB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor IL2RB expression. Decide whether this perturbation leads to a significant alteration in IL2RB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2113,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and PELO expression is observed. Does this perturbation lead to a significant difference in PELO expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and PELO expression is observed. Does this perturbation lead to a significant difference in PELO expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and IRF7 expression is quantified. Does this perturbation result in a significant change in IRF7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and IRF7 expression is quantified. Does this perturbation result in a significant change in IRF7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4500,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of BIRC5 is measured. Does this perturbation cause a significant change in BIRC5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of BIRC5 is measured. Does this perturbation cause a significant change in BIRC5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and TOPBP1 expression is quantified. Does this perturbation result in a significant change in TOPBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and TOPBP1 expression is quantified. Does this perturbation result in a significant change in TOPBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of RP11-435O5.4 is measured. Determine whether RP11-435O5.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of RP11-435O5.4 is measured. Determine whether RP11-435O5.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1068,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor KHDC1L expression. Decide whether this perturbation leads to a significant alteration in KHDC1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor KHDC1L expression. Decide whether this perturbation leads to a significant alteration in KHDC1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3343,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and SIGLEC6 expression is observed. Does this perturbation lead to a significant difference in SIGLEC6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and SIGLEC6 expression is observed. Does this perturbation lead to a significant difference in SIGLEC6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and ATP6AP2 expression is measured. Determine whether ATP6AP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and ATP6AP2 expression is measured. Determine whether ATP6AP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and CYP17A1-AS1 expression is quantified. Does this perturbation result in a significant change in CYP17A1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and CYP17A1-AS1 expression is quantified. Does this perturbation result in a significant change in CYP17A1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of PTGS1. Does this perturbation cause a significant change in PTGS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of PTGS1. Does this perturbation cause a significant change in PTGS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of EXOC3L2. Does this perturbation cause a significant change in EXOC3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of EXOC3L2. Does this perturbation cause a significant change in EXOC3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and EXO1 expression is measured. Determine whether EXO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and EXO1 expression is measured. Determine whether EXO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of FAM114A1 is measured. Determine whether FAM114A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of FAM114A1 is measured. Determine whether FAM114A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and KCTD19 expression is measured. Determine whether KCTD19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and KCTD19 expression is measured. Determine whether KCTD19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and GSN expression is measured. Determine whether GSN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and GSN expression is measured. Determine whether GSN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3430,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP5 is measured. Does this perturbation cause a significant change in ARHGAP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP5 is measured. Does this perturbation cause a significant change in ARHGAP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of AKAP11. Does perturbing TMEM167A lead to a significant change in AKAP11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of AKAP11. Does perturbing TMEM167A lead to a significant change in AKAP11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of DOCK11. Does this perturbation cause a significant change in DOCK11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of DOCK11. Does this perturbation cause a significant change in DOCK11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and BIRC5 expression is quantified. Does this perturbation result in a significant change in BIRC5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and BIRC5 expression is quantified. Does this perturbation result in a significant change in BIRC5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of EIF4B. Does this perturbation cause a significant change in EIF4B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of EIF4B. Does this perturbation cause a significant change in EIF4B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ARHGAP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ARHGAP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RAI14 expression is measured. Determine whether RAI14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RAI14 expression is measured. Determine whether RAI14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and RP11-334C17.5 expression is quantified. Does this perturbation result in a significant change in RP11-334C17.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and RP11-334C17.5 expression is quantified. Does this perturbation result in a significant change in RP11-334C17.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and TLK2 expression is measured. Determine whether TLK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and TLK2 expression is measured. Determine whether TLK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of LBX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of LBX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of RGS20. Does this perturbation cause a significant change in RGS20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of RGS20. Does this perturbation cause a significant change in RGS20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
178,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor TKTL1 expression. Decide whether this perturbation leads to a significant alteration in TKTL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor TKTL1 expression. Decide whether this perturbation leads to a significant alteration in TKTL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3318,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor EGLN3 expression. Decide whether this perturbation leads to a significant alteration in EGLN3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor EGLN3 expression. Decide whether this perturbation leads to a significant alteration in EGLN3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of RP11-334C17.5 is measured. Determine whether RP11-334C17.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of RP11-334C17.5 is measured. Determine whether RP11-334C17.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in FAM212A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in FAM212A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and QSER1 expression is measured. Determine whether QSER1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and QSER1 expression is measured. Determine whether QSER1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
323,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and LTB expression is observed. Does this perturbation lead to a significant difference in LTB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and LTB expression is observed. Does this perturbation lead to a significant difference in LTB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of PCF11 is measured. Determine whether PCF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of PCF11 is measured. Determine whether PCF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and PAXBP1 expression is measured. Determine whether PAXBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and PAXBP1 expression is measured. Determine whether PAXBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of ZNF678 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of ZNF678 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and OBSCN expression is quantified. Does this perturbation result in a significant change in OBSCN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and OBSCN expression is quantified. Does this perturbation result in a significant change in OBSCN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of SMCO1 is measured. Determine whether SMCO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of SMCO1 is measured. Determine whether SMCO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2840,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of SPAST is measured. Does this perturbation cause a significant change in SPAST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of SPAST is measured. Does this perturbation cause a significant change in SPAST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of PTAR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of PTAR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2320,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of H3F3B is measured. Does this perturbation cause a significant change in H3F3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of H3F3B is measured. Does this perturbation cause a significant change in H3F3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1690,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4508,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor BIRC5 expression. Decide whether this perturbation leads to a significant alteration in BIRC5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor BIRC5 expression. Decide whether this perturbation leads to a significant alteration in BIRC5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
95,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RP11-141B14.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RP11-141B14.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of CDRT4. Does this perturbation cause a significant change in CDRT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of CDRT4. Does this perturbation cause a significant change in CDRT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in OBSCN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in OBSCN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of KLF3. Does this perturbation cause a significant change in KLF3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of KLF3. Does this perturbation cause a significant change in KLF3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of NAV1. Does this perturbation cause a significant change in NAV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of NAV1. Does this perturbation cause a significant change in NAV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and KIAA1586 expression is quantified. Does this perturbation result in a significant change in KIAA1586 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and KIAA1586 expression is quantified. Does this perturbation result in a significant change in KIAA1586 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of ANKRD10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of ANKRD10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of PIK3R3. Does this perturbation cause a significant change in PIK3R3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of PIK3R3. Does this perturbation cause a significant change in PIK3R3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RGS20 expression is measured. Determine whether RGS20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RGS20 expression is measured. Determine whether RGS20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of UFD1L. Does this perturbation cause a significant change in UFD1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of UFD1L. Does this perturbation cause a significant change in UFD1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
650,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of POU2F2 is measured. Does this perturbation cause a significant change in POU2F2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of POU2F2 is measured. Does this perturbation cause a significant change in POU2F2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of C10orf32 is measured. Determine whether C10orf32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of C10orf32 is measured. Determine whether C10orf32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4253,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and PAK1IP1 expression is observed. Does this perturbation lead to a significant difference in PAK1IP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and PAK1IP1 expression is observed. Does this perturbation lead to a significant difference in PAK1IP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of RP11-363D14.1. Does this perturbation cause a significant change in RP11-363D14.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of RP11-363D14.1. Does this perturbation cause a significant change in RP11-363D14.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in C9orf64 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in C9orf64 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of UQCRB. Does perturbing SLMO2 lead to a significant change in UQCRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of UQCRB. Does perturbing SLMO2 lead to a significant change in UQCRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and RCBTB2 expression is quantified. Does this perturbation result in a significant change in RCBTB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and RCBTB2 expression is quantified. Does this perturbation result in a significant change in RCBTB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2150,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of SNRNP25 is measured. Does this perturbation cause a significant change in SNRNP25 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of SNRNP25 is measured. Does this perturbation cause a significant change in SNRNP25 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and ATAD2B expression is quantified. Does this perturbation result in a significant change in ATAD2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and ATAD2B expression is quantified. Does this perturbation result in a significant change in ATAD2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and S100A11 expression is quantified. Does this perturbation result in a significant change in S100A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and S100A11 expression is quantified. Does this perturbation result in a significant change in S100A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3120,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of RGS20 is measured. Does this perturbation cause a significant change in RGS20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of RGS20 is measured. Does this perturbation cause a significant change in RGS20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1920,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of AKAP11 is measured. Does this perturbation cause a significant change in AKAP11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of AKAP11 is measured. Does this perturbation cause a significant change in AKAP11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
618,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor HP1BP3 expression. Decide whether this perturbation leads to a significant alteration in HP1BP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor HP1BP3 expression. Decide whether this perturbation leads to a significant alteration in HP1BP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of RP3-465N24.6. Does this perturbation cause a significant change in RP3-465N24.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of RP3-465N24.6. Does this perturbation cause a significant change in RP3-465N24.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in SLC25A35 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in SLC25A35 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ZFP36L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ZFP36L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
320,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of LTB is measured. Does this perturbation cause a significant change in LTB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of LTB is measured. Does this perturbation cause a significant change in LTB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and AC005540.3 expression is measured. Determine whether AC005540.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and AC005540.3 expression is measured. Determine whether AC005540.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and TMOD3 expression is quantified. Does this perturbation result in a significant change in TMOD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and TMOD3 expression is quantified. Does this perturbation result in a significant change in TMOD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of ATP5EP2. Does perturbing ASCC3 lead to a significant change in ATP5EP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of ATP5EP2. Does perturbing ASCC3 lead to a significant change in ATP5EP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of PCF11 is measured. Determine whether PCF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of PCF11 is measured. Determine whether PCF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of RP11-61E11.1. Does this perturbation cause a significant change in RP11-61E11.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of RP11-61E11.1. Does this perturbation cause a significant change in RP11-61E11.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of PTPN11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of PTPN11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of EIF3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of EIF3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of LST1. Does perturbing SYVN1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of LST1. Does perturbing SYVN1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and CTCFL expression is quantified. Does this perturbation result in a significant change in CTCFL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and CTCFL expression is quantified. Does this perturbation result in a significant change in CTCFL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3310,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of EGLN3 is measured. Does this perturbation cause a significant change in EGLN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of EGLN3 is measured. Does this perturbation cause a significant change in EGLN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and IL32 expression is measured. Determine whether IL32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and IL32 expression is measured. Determine whether IL32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and CMTM6 expression is quantified. Does this perturbation result in a significant change in CMTM6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and CMTM6 expression is quantified. Does this perturbation result in a significant change in CMTM6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of WHAMM. Does perturbing TIMM23 lead to a significant change in WHAMM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of WHAMM. Does perturbing TIMM23 lead to a significant change in WHAMM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and HRK expression is measured. Determine whether HRK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and HRK expression is measured. Determine whether HRK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of CTC-308K20.1. Does perturbing SPCS2 lead to a significant change in CTC-308K20.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of CTC-308K20.1. Does perturbing SPCS2 lead to a significant change in CTC-308K20.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4220,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of IFT27 is measured. Does this perturbation cause a significant change in IFT27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of IFT27 is measured. Does this perturbation cause a significant change in IFT27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of SETD5-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of SETD5-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and RP11-181G12.2 expression is quantified. Does this perturbation result in a significant change in RP11-181G12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and RP11-181G12.2 expression is quantified. Does this perturbation result in a significant change in RP11-181G12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
923,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and SPAST expression is observed. Does this perturbation lead to a significant difference in SPAST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and SPAST expression is observed. Does this perturbation lead to a significant difference in SPAST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and SERPING1 expression is quantified. Does this perturbation result in a significant change in SERPING1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and SERPING1 expression is quantified. Does this perturbation result in a significant change in SERPING1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
438,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor CLINT1 expression. Decide whether this perturbation leads to a significant alteration in CLINT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor CLINT1 expression. Decide whether this perturbation leads to a significant alteration in CLINT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4993,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and ZCCHC11 expression is observed. Does this perturbation lead to a significant difference in ZCCHC11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and ZCCHC11 expression is observed. Does this perturbation lead to a significant difference in ZCCHC11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of DST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of DST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and NFE2 expression is measured. Determine whether NFE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and NFE2 expression is measured. Determine whether NFE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of CTSF. Does this perturbation cause a significant change in CTSF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of CTSF. Does this perturbation cause a significant change in CTSF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and TROAP expression is measured. Determine whether TROAP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and TROAP expression is measured. Determine whether TROAP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of MORC2-AS1 is measured. Determine whether MORC2-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of MORC2-AS1 is measured. Determine whether MORC2-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of DOK3. Does this perturbation cause a significant change in DOK3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of DOK3. Does this perturbation cause a significant change in DOK3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of RP11-81A22.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of RP11-81A22.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
378,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor HMGCS1 expression. Decide whether this perturbation leads to a significant alteration in HMGCS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor HMGCS1 expression. Decide whether this perturbation leads to a significant alteration in HMGCS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and SEC23IP expression is measured. Determine whether SEC23IP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and SEC23IP expression is measured. Determine whether SEC23IP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in RP11-119J18.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in RP11-119J18.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of RILPL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of RILPL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
958,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor HERC2 expression. Decide whether this perturbation leads to a significant alteration in HERC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor HERC2 expression. Decide whether this perturbation leads to a significant alteration in HERC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and GCKR expression is quantified. Does this perturbation result in a significant change in GCKR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and GCKR expression is quantified. Does this perturbation result in a significant change in GCKR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and DUSP21 expression is quantified. Does this perturbation result in a significant change in DUSP21 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and DUSP21 expression is quantified. Does this perturbation result in a significant change in DUSP21 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of OPTN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of OPTN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of C1GALT1 is measured. Determine whether C1GALT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of C1GALT1 is measured. Determine whether C1GALT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and RP11-24F11.2 expression is quantified. Does this perturbation result in a significant change in RP11-24F11.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and RP11-24F11.2 expression is quantified. Does this perturbation result in a significant change in RP11-24F11.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of HLA-AS1. Does this perturbation cause a significant change in HLA-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of HLA-AS1. Does this perturbation cause a significant change in HLA-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in BRWD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in BRWD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of TET1. Does perturbing BHLHE40 lead to a significant change in TET1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of TET1. Does perturbing BHLHE40 lead to a significant change in TET1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5008,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor QSER1 expression. Decide whether this perturbation leads to a significant alteration in QSER1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor QSER1 expression. Decide whether this perturbation leads to a significant alteration in QSER1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2143,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and NINJ2 expression is observed. Does this perturbation lead to a significant difference in NINJ2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and NINJ2 expression is observed. Does this perturbation lead to a significant difference in NINJ2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and SIGLEC6 expression is measured. Determine whether SIGLEC6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and SIGLEC6 expression is measured. Determine whether SIGLEC6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of TOPBP1. Does perturbing HYOU1 lead to a significant change in TOPBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of TOPBP1. Does perturbing HYOU1 lead to a significant change in TOPBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2890,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of TOPBP1 is measured. Does this perturbation cause a significant change in TOPBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of TOPBP1 is measured. Does this perturbation cause a significant change in TOPBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and ANKRD10 expression is quantified. Does this perturbation result in a significant change in ANKRD10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and ANKRD10 expression is quantified. Does this perturbation result in a significant change in ANKRD10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in PCK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in PCK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of PTGS1. Does perturbing SCYL1 lead to a significant change in PTGS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of PTGS1. Does perturbing SCYL1 lead to a significant change in PTGS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3710,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of C17orf64 is measured. Does this perturbation cause a significant change in C17orf64 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of C17orf64 is measured. Does this perturbation cause a significant change in C17orf64 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and TMEM60 expression is measured. Determine whether TMEM60 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and TMEM60 expression is measured. Determine whether TMEM60 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PSMD14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PSMD14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of TOB2. Does this perturbation cause a significant change in TOB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of TOB2. Does this perturbation cause a significant change in TOB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and BACH2 expression is quantified. Does this perturbation result in a significant change in BACH2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and BACH2 expression is quantified. Does this perturbation result in a significant change in BACH2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of TMEM87B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of TMEM87B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
420,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of CD9 is measured. Does this perturbation cause a significant change in CD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of CD9 is measured. Does this perturbation cause a significant change in CD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ARHGAP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ARHGAP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and ANXA4 expression is quantified. Does this perturbation result in a significant change in ANXA4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and ANXA4 expression is quantified. Does this perturbation result in a significant change in ANXA4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4468,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor NAV1 expression. Decide whether this perturbation leads to a significant alteration in NAV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor NAV1 expression. Decide whether this perturbation leads to a significant alteration in NAV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and SSBP2 expression is quantified. Does this perturbation result in a significant change in SSBP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and SSBP2 expression is quantified. Does this perturbation result in a significant change in SSBP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of RP11-445H22.3. Does this perturbation cause a significant change in RP11-445H22.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of RP11-445H22.3. Does this perturbation cause a significant change in RP11-445H22.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and AC018878.3 expression is measured. Determine whether AC018878.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and AC018878.3 expression is measured. Determine whether AC018878.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
293,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and ATP11B expression is observed. Does this perturbation lead to a significant difference in ATP11B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and ATP11B expression is observed. Does this perturbation lead to a significant difference in ATP11B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
690,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of SPCS2 is measured. Does this perturbation cause a significant change in SPCS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of SPCS2 is measured. Does this perturbation cause a significant change in SPCS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of RSAD2. Does this perturbation cause a significant change in RSAD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of RSAD2. Does this perturbation cause a significant change in RSAD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and LTBP1 expression is quantified. Does this perturbation result in a significant change in LTBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and LTBP1 expression is quantified. Does this perturbation result in a significant change in LTBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4783,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and PDE3B expression is observed. Does this perturbation lead to a significant difference in PDE3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and PDE3B expression is observed. Does this perturbation lead to a significant difference in PDE3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in ARHGAP30 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in ARHGAP30 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in DKFZP779L1853 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in DKFZP779L1853 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4640,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of S100A11 is measured. Does this perturbation cause a significant change in S100A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of S100A11 is measured. Does this perturbation cause a significant change in S100A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PHF19. Does this perturbation cause a significant change in PHF19 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PHF19. Does this perturbation cause a significant change in PHF19 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and TLK2 expression is quantified. Does this perturbation result in a significant change in TLK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and TLK2 expression is quantified. Does this perturbation result in a significant change in TLK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of OPTN is measured. Determine whether OPTN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of OPTN is measured. Determine whether OPTN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3303,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and SMIM14 expression is observed. Does this perturbation lead to a significant difference in SMIM14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and SMIM14 expression is observed. Does this perturbation lead to a significant difference in SMIM14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and BAMBI expression is quantified. Does this perturbation result in a significant change in BAMBI expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and BAMBI expression is quantified. Does this perturbation result in a significant change in BAMBI expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and CHD3 expression is quantified. Does this perturbation result in a significant change in CHD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and CHD3 expression is quantified. Does this perturbation result in a significant change in CHD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of LINC00938 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of LINC00938 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3420,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP6 is measured. Does this perturbation cause a significant change in ARHGAP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP6 is measured. Does this perturbation cause a significant change in ARHGAP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of ARHGAP30 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of ARHGAP30 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
16,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of P4HA2 is measured. Determine whether P4HA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of P4HA2 is measured. Determine whether P4HA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and NFAT5 expression is measured. Determine whether NFAT5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and NFAT5 expression is measured. Determine whether NFAT5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of ACSM3 is measured. Determine whether ACSM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of ACSM3 is measured. Determine whether ACSM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in NFE2L3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in NFE2L3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of DNMBP is measured. Determine whether DNMBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of DNMBP is measured. Determine whether DNMBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and SAMM50 expression is measured. Determine whether SAMM50 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and SAMM50 expression is measured. Determine whether SAMM50 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of NUFIP2. Does this perturbation cause a significant change in NUFIP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of NUFIP2. Does this perturbation cause a significant change in NUFIP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
248,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor UHRF1BP1L expression. Decide whether this perturbation leads to a significant alteration in UHRF1BP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor UHRF1BP1L expression. Decide whether this perturbation leads to a significant alteration in UHRF1BP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4063,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and CENPF expression is observed. Does this perturbation lead to a significant difference in CENPF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and CENPF expression is observed. Does this perturbation lead to a significant difference in CENPF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in SNHG10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in SNHG10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
818,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor DNTTIP2 expression. Decide whether this perturbation leads to a significant alteration in DNTTIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor DNTTIP2 expression. Decide whether this perturbation leads to a significant alteration in DNTTIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in GCKR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in GCKR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2093,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1063,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and KHDC1L expression is observed. Does this perturbation lead to a significant difference in KHDC1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and KHDC1L expression is observed. Does this perturbation lead to a significant difference in KHDC1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of CDKN2C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of CDKN2C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and IL13RA1 expression is quantified. Does this perturbation result in a significant change in IL13RA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and IL13RA1 expression is quantified. Does this perturbation result in a significant change in IL13RA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of UBE2V1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of UBE2V1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of SNHG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of SNHG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4458,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor CENPC expression. Decide whether this perturbation leads to a significant alteration in CENPC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor CENPC expression. Decide whether this perturbation leads to a significant alteration in CENPC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of CRYM. Does perturbing MARS lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of CRYM. Does perturbing MARS lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of RP11-15E18.1. Does this perturbation cause a significant change in RP11-15E18.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of RP11-15E18.1. Does this perturbation cause a significant change in RP11-15E18.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of KHDC1L. Does perturbing IARS2 lead to a significant change in KHDC1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of KHDC1L. Does perturbing IARS2 lead to a significant change in KHDC1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2513,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and RBM12B-AS1 expression is observed. Does this perturbation lead to a significant difference in RBM12B-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and RBM12B-AS1 expression is observed. Does this perturbation lead to a significant difference in RBM12B-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in SSBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in SSBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of CTBS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of CTBS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3740,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of KIAA0922 is measured. Does this perturbation cause a significant change in KIAA0922 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of KIAA0922 is measured. Does this perturbation cause a significant change in KIAA0922 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of RP11-181G12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of RP11-181G12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1483,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and WHSC1 expression is observed. Does this perturbation lead to a significant difference in WHSC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and WHSC1 expression is observed. Does this perturbation lead to a significant difference in WHSC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of RP11-2H8.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of RP11-2H8.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of RP11-16E12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of RP11-16E12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of SSBP2. Does this perturbation cause a significant change in SSBP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of SSBP2. Does this perturbation cause a significant change in SSBP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1213,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and JARID2 expression is observed. Does this perturbation lead to a significant difference in JARID2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and JARID2 expression is observed. Does this perturbation lead to a significant difference in JARID2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of CST7. Does this perturbation cause a significant change in CST7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of CST7. Does this perturbation cause a significant change in CST7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of C3AR1. Does perturbing SRP72 lead to a significant change in C3AR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of C3AR1. Does perturbing SRP72 lead to a significant change in C3AR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1808,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor LTBP1 expression. Decide whether this perturbation leads to a significant alteration in LTBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor LTBP1 expression. Decide whether this perturbation leads to a significant alteration in LTBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2130,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of SLBP is measured. Does this perturbation cause a significant change in SLBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of SLBP is measured. Does this perturbation cause a significant change in SLBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
718,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor FAM114A1 expression. Decide whether this perturbation leads to a significant alteration in FAM114A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor FAM114A1 expression. Decide whether this perturbation leads to a significant alteration in FAM114A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4843,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and EPS15 expression is observed. Does this perturbation lead to a significant difference in EPS15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and EPS15 expression is observed. Does this perturbation lead to a significant difference in EPS15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of TSPAN33. Does this perturbation cause a significant change in TSPAN33 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of TSPAN33. Does this perturbation cause a significant change in TSPAN33 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of CTSF. Does perturbing BHLHE40 lead to a significant change in CTSF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of CTSF. Does perturbing BHLHE40 lead to a significant change in CTSF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2983,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and AC104532.4 expression is observed. Does this perturbation lead to a significant difference in AC104532.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and AC104532.4 expression is observed. Does this perturbation lead to a significant difference in AC104532.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
270,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of DUT is measured. Does this perturbation cause a significant change in DUT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of DUT is measured. Does this perturbation cause a significant change in DUT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of YTHDF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of YTHDF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2038,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor RP11-212I21.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-212I21.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor RP11-212I21.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-212I21.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of P4HA2. Does perturbing MRPL39 lead to a significant change in P4HA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of P4HA2. Does perturbing MRPL39 lead to a significant change in P4HA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of IFNGR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of IFNGR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3633,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and SOBP expression is observed. Does this perturbation lead to a significant difference in SOBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and SOBP expression is observed. Does this perturbation lead to a significant difference in SOBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of CTCFL. Does perturbing SEC63 lead to a significant change in CTCFL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of CTCFL. Does perturbing SEC63 lead to a significant change in CTCFL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and RP11-15E18.1 expression is quantified. Does this perturbation result in a significant change in RP11-15E18.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and RP11-15E18.1 expression is quantified. Does this perturbation result in a significant change in RP11-15E18.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of NAV2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of NAV2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4698,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor ANKRD11 expression. Decide whether this perturbation leads to a significant alteration in ANKRD11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor ANKRD11 expression. Decide whether this perturbation leads to a significant alteration in ANKRD11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2923,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and AC007038.7 expression is observed. Does this perturbation lead to a significant difference in AC007038.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and AC007038.7 expression is observed. Does this perturbation lead to a significant difference in AC007038.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1428,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor RP11-61E11.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-61E11.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor RP11-61E11.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-61E11.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and MBNL1 expression is quantified. Does this perturbation result in a significant change in MBNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and MBNL1 expression is quantified. Does this perturbation result in a significant change in MBNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of LRIF1. Does perturbing MRGBP lead to a significant change in LRIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of LRIF1. Does perturbing MRGBP lead to a significant change in LRIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of RP11-499F3.2. Does perturbing TARS lead to a significant change in RP11-499F3.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of RP11-499F3.2. Does perturbing TARS lead to a significant change in RP11-499F3.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1440,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of AC079466.1 is measured. Does this perturbation cause a significant change in AC079466.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of AC079466.1 is measured. Does this perturbation cause a significant change in AC079466.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of PLB1. Does perturbing TMED2 lead to a significant change in PLB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of PLB1. Does perturbing TMED2 lead to a significant change in PLB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in NUF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in NUF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3130,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of LTN1 is measured. Does this perturbation cause a significant change in LTN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of LTN1 is measured. Does this perturbation cause a significant change in LTN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of RP11-242O24.5. Does perturbing TMED10 lead to a significant change in RP11-242O24.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of RP11-242O24.5. Does perturbing TMED10 lead to a significant change in RP11-242O24.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and SERPINF2 expression is measured. Determine whether SERPINF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and SERPINF2 expression is measured. Determine whether SERPINF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of RSAD2 is measured. Determine whether RSAD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of RSAD2 is measured. Determine whether RSAD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4390,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of ATAD2B is measured. Does this perturbation cause a significant change in ATAD2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of ATAD2B is measured. Does this perturbation cause a significant change in ATAD2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of PHF21A is measured. Determine whether PHF21A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of PHF21A is measured. Determine whether PHF21A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in RCBTB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in RCBTB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of CDCA3 is measured. Determine whether CDCA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of CDCA3 is measured. Determine whether CDCA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of MED13. Does this perturbation cause a significant change in MED13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of MED13. Does this perturbation cause a significant change in MED13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of C17orf64. Does this perturbation cause a significant change in C17orf64 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of C17orf64. Does this perturbation cause a significant change in C17orf64 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and PARP11 expression is quantified. Does this perturbation result in a significant change in PARP11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and PARP11 expression is quantified. Does this perturbation result in a significant change in PARP11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and SETX expression is quantified. Does this perturbation result in a significant change in SETX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and SETX expression is quantified. Does this perturbation result in a significant change in SETX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and RP11-322J23.1 expression is measured. Determine whether RP11-322J23.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and RP11-322J23.1 expression is measured. Determine whether RP11-322J23.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and OR2T6 expression is quantified. Does this perturbation result in a significant change in OR2T6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and OR2T6 expression is quantified. Does this perturbation result in a significant change in OR2T6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and TRIM24 expression is quantified. Does this perturbation result in a significant change in TRIM24 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and TRIM24 expression is quantified. Does this perturbation result in a significant change in TRIM24 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4350,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of ANKRD10 is measured. Does this perturbation cause a significant change in ANKRD10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of ANKRD10 is measured. Does this perturbation cause a significant change in ANKRD10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and ABI2 expression is measured. Determine whether ABI2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and ABI2 expression is measured. Determine whether ABI2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of KIAA0922 is measured. Determine whether KIAA0922 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of KIAA0922 is measured. Determine whether KIAA0922 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of PTBP3 is measured. Determine whether PTBP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of PTBP3 is measured. Determine whether PTBP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ROBO1 is measured. Determine whether ROBO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ROBO1 is measured. Determine whether ROBO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of ATP6V1B2. Does perturbing PDIA6 lead to a significant change in ATP6V1B2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of ATP6V1B2. Does perturbing PDIA6 lead to a significant change in ATP6V1B2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in CTNNB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in CTNNB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1288,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor ZNF280B expression. Decide whether this perturbation leads to a significant alteration in ZNF280B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor ZNF280B expression. Decide whether this perturbation leads to a significant alteration in ZNF280B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of KIAA1586. Does perturbing EIF2B3 lead to a significant change in KIAA1586 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of KIAA1586. Does perturbing EIF2B3 lead to a significant change in KIAA1586 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3853,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and PHF21A expression is observed. Does this perturbation lead to a significant difference in PHF21A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and PHF21A expression is observed. Does this perturbation lead to a significant difference in PHF21A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and SBF2 expression is measured. Determine whether SBF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and SBF2 expression is measured. Determine whether SBF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of GMEB1. Does this perturbation cause a significant change in GMEB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of GMEB1. Does this perturbation cause a significant change in GMEB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4228,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor IFT27 expression. Decide whether this perturbation leads to a significant alteration in IFT27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor IFT27 expression. Decide whether this perturbation leads to a significant alteration in IFT27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in PTAR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in PTAR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and SPINK5 expression is measured. Determine whether SPINK5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and SPINK5 expression is measured. Determine whether SPINK5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of OR2T6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of OR2T6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in LAMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in LAMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in CTSF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in CTSF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4870,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of S100A10 is measured. Does this perturbation cause a significant change in S100A10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of S100A10 is measured. Does this perturbation cause a significant change in S100A10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4410,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of AC005540.3 is measured. Does this perturbation cause a significant change in AC005540.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of AC005540.3 is measured. Does this perturbation cause a significant change in AC005540.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3513,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and TMEM60 expression is observed. Does this perturbation lead to a significant difference in TMEM60 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and TMEM60 expression is observed. Does this perturbation lead to a significant difference in TMEM60 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
15,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in P4HA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in P4HA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of PDE4D is measured. Determine whether PDE4D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of PDE4D is measured. Determine whether PDE4D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of IL2RB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of IL2RB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1570,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of SPEN is measured. Does this perturbation cause a significant change in SPEN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of SPEN is measured. Does this perturbation cause a significant change in SPEN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1248,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor CYP17A1-AS1 expression. Decide whether this perturbation leads to a significant alteration in CYP17A1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor CYP17A1-AS1 expression. Decide whether this perturbation leads to a significant alteration in CYP17A1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of PTPRC is measured. Determine whether PTPRC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of PTPRC is measured. Determine whether PTPRC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of STC2. Does perturbing DDIT3 lead to a significant change in STC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of STC2. Does perturbing DDIT3 lead to a significant change in STC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and SHOX2 expression is quantified. Does this perturbation result in a significant change in SHOX2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and SHOX2 expression is quantified. Does this perturbation result in a significant change in SHOX2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of HRK. Does perturbing IARS2 lead to a significant change in HRK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of HRK. Does perturbing IARS2 lead to a significant change in HRK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2930,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of RP11-227G15.8 is measured. Does this perturbation cause a significant change in RP11-227G15.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of RP11-227G15.8 is measured. Does this perturbation cause a significant change in RP11-227G15.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of PDE3B is measured. Determine whether PDE3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of PDE3B is measured. Determine whether PDE3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of ANKRD11 is measured. Determine whether ANKRD11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of ANKRD11 is measured. Determine whether ANKRD11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1130,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1858,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor TRAPPC10 expression. Decide whether this perturbation leads to a significant alteration in TRAPPC10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor TRAPPC10 expression. Decide whether this perturbation leads to a significant alteration in TRAPPC10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in HERPUD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in HERPUD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of SLC25A35. Does this perturbation cause a significant change in SLC25A35 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of SLC25A35. Does this perturbation cause a significant change in SLC25A35 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in SPCS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in SPCS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of CFH. Does this perturbation cause a significant change in CFH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of CFH. Does this perturbation cause a significant change in CFH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1220,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of UBE3A is measured. Does this perturbation cause a significant change in UBE3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of UBE3A is measured. Does this perturbation cause a significant change in UBE3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of F2RL2. Does perturbing TELO2 lead to a significant change in F2RL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of F2RL2. Does perturbing TELO2 lead to a significant change in F2RL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3150,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of SLC25A35 is measured. Does this perturbation cause a significant change in SLC25A35 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of SLC25A35 is measured. Does this perturbation cause a significant change in SLC25A35 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and KCNJ13 expression is measured. Determine whether KCNJ13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and KCNJ13 expression is measured. Determine whether KCNJ13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP5 is measured. Determine whether ARHGAP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP5 is measured. Determine whether ARHGAP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2483,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and HLTF expression is observed. Does this perturbation lead to a significant difference in HLTF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and HLTF expression is observed. Does this perturbation lead to a significant difference in HLTF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of AC015987.2. Does this perturbation cause a significant change in AC015987.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of AC015987.2. Does this perturbation cause a significant change in AC015987.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of LTN1. Does this perturbation cause a significant change in LTN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of LTN1. Does this perturbation cause a significant change in LTN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of TOPBP1. Does this perturbation cause a significant change in TOPBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of TOPBP1. Does this perturbation cause a significant change in TOPBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1550,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of RP11-381O7.3 is measured. Does this perturbation cause a significant change in RP11-381O7.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of RP11-381O7.3 is measured. Does this perturbation cause a significant change in RP11-381O7.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of RP11-434H6.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of RP11-434H6.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of KIAA0922 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of KIAA0922 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4958,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor PLB1 expression. Decide whether this perturbation leads to a significant alteration in PLB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor PLB1 expression. Decide whether this perturbation leads to a significant alteration in PLB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and OPTN expression is quantified. Does this perturbation result in a significant change in OPTN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and OPTN expression is quantified. Does this perturbation result in a significant change in OPTN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of CMTM6 is measured. Determine whether CMTM6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of CMTM6 is measured. Determine whether CMTM6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and SDF4 expression is quantified. Does this perturbation result in a significant change in SDF4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and SDF4 expression is quantified. Does this perturbation result in a significant change in SDF4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PSMD14 expression is quantified. Does this perturbation result in a significant change in PSMD14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PSMD14 expression is quantified. Does this perturbation result in a significant change in PSMD14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in STC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in STC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and C12orf44 expression is measured. Determine whether C12orf44 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and C12orf44 expression is measured. Determine whether C12orf44 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of EIF4B. Does perturbing TMED2 lead to a significant change in EIF4B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of EIF4B. Does perturbing TMED2 lead to a significant change in EIF4B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
148,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor RDH10 expression. Decide whether this perturbation leads to a significant alteration in RDH10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor RDH10 expression. Decide whether this perturbation leads to a significant alteration in RDH10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of WHSC1. Does perturbing MRGBP lead to a significant change in WHSC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of WHSC1. Does perturbing MRGBP lead to a significant change in WHSC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of SNHG10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of SNHG10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of IL2RB. Does this perturbation cause a significant change in IL2RB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of IL2RB. Does this perturbation cause a significant change in IL2RB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and MANF expression is quantified. Does this perturbation result in a significant change in MANF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and MANF expression is quantified. Does this perturbation result in a significant change in MANF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in RP11-328J2.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in RP11-328J2.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3018,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor PCK2 expression. Decide whether this perturbation leads to a significant alteration in PCK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor PCK2 expression. Decide whether this perturbation leads to a significant alteration in PCK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of SLFNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of SLFNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and RP11-328J2.1 expression is quantified. Does this perturbation result in a significant change in RP11-328J2.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and RP11-328J2.1 expression is quantified. Does this perturbation result in a significant change in RP11-328J2.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1160,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of KDM1B is measured. Does this perturbation cause a significant change in KDM1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of KDM1B is measured. Does this perturbation cause a significant change in KDM1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3250,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of S100A11 is measured. Does this perturbation cause a significant change in S100A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of S100A11 is measured. Does this perturbation cause a significant change in S100A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1883,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and SNHG10 expression is observed. Does this perturbation lead to a significant difference in SNHG10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and SNHG10 expression is observed. Does this perturbation lead to a significant difference in SNHG10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and JUND expression is measured. Determine whether JUND exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and JUND expression is measured. Determine whether JUND exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and CTD-2521M24.9 expression is measured. Determine whether CTD-2521M24.9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and CTD-2521M24.9 expression is measured. Determine whether CTD-2521M24.9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
348,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor MS4A6E expression. Decide whether this perturbation leads to a significant alteration in MS4A6E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor MS4A6E expression. Decide whether this perturbation leads to a significant alteration in MS4A6E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and CTD-2521M24.9 expression is quantified. Does this perturbation result in a significant change in CTD-2521M24.9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and CTD-2521M24.9 expression is quantified. Does this perturbation result in a significant change in CTD-2521M24.9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and NBEAL2 expression is measured. Determine whether NBEAL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and NBEAL2 expression is measured. Determine whether NBEAL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in CMTM6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in CMTM6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5073,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and ERP29 expression is observed. Does this perturbation lead to a significant difference in ERP29 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and ERP29 expression is observed. Does this perturbation lead to a significant difference in ERP29 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and ITGB2 expression is quantified. Does this perturbation result in a significant change in ITGB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and ITGB2 expression is quantified. Does this perturbation result in a significant change in ITGB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in EXO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in EXO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of TLN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of TLN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in CTC-550B14.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in CTC-550B14.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of BIRC5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of BIRC5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and PTBP3 expression is measured. Determine whether PTBP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and PTBP3 expression is measured. Determine whether PTBP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4628,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor KCNQ1OT1 expression. Decide whether this perturbation leads to a significant alteration in KCNQ1OT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor KCNQ1OT1 expression. Decide whether this perturbation leads to a significant alteration in KCNQ1OT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of TNFRSF10B. Does perturbing TELO2 lead to a significant change in TNFRSF10B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of TNFRSF10B. Does perturbing TELO2 lead to a significant change in TNFRSF10B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ARHGAP6 expression is quantified. Does this perturbation result in a significant change in ARHGAP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ARHGAP6 expression is quantified. Does this perturbation result in a significant change in ARHGAP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and WDR3 expression is quantified. Does this perturbation result in a significant change in WDR3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and WDR3 expression is quantified. Does this perturbation result in a significant change in WDR3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in CCRL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in CCRL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of ZEB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of ZEB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in C10orf32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in C10orf32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of KCNE3. Does perturbing IDH3A lead to a significant change in KCNE3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of KCNE3. Does perturbing IDH3A lead to a significant change in KCNE3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of RNF19A. Does perturbing PTDSS1 lead to a significant change in RNF19A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of RNF19A. Does perturbing PTDSS1 lead to a significant change in RNF19A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of ARHGAP11A. Does perturbing PTDSS1 lead to a significant change in ARHGAP11A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of ARHGAP11A. Does perturbing PTDSS1 lead to a significant change in ARHGAP11A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of PAXBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of PAXBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of LTB. Does perturbing SEC61G lead to a significant change in LTB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of LTB. Does perturbing SEC61G lead to a significant change in LTB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in SLC27A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in SLC27A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5150,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of ROCK1 is measured. Does this perturbation cause a significant change in ROCK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of ROCK1 is measured. Does this perturbation cause a significant change in ROCK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of TRIM24. Does perturbing TTI1 lead to a significant change in TRIM24 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of TRIM24. Does perturbing TTI1 lead to a significant change in TRIM24 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and ZNF789 expression is measured. Determine whether ZNF789 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and ZNF789 expression is measured. Determine whether ZNF789 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5003,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and QSER1 expression is observed. Does this perturbation lead to a significant difference in QSER1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and QSER1 expression is observed. Does this perturbation lead to a significant difference in QSER1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in RILPL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in RILPL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1978,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor CRNDE expression. Decide whether this perturbation leads to a significant alteration in CRNDE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor CRNDE expression. Decide whether this perturbation leads to a significant alteration in CRNDE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and ZNF280B expression is measured. Determine whether ZNF280B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and ZNF280B expression is measured. Determine whether ZNF280B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4563,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and WDR3 expression is observed. Does this perturbation lead to a significant difference in WDR3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and WDR3 expression is observed. Does this perturbation lead to a significant difference in WDR3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of ATXN7L3B. Does perturbing TMED2 lead to a significant change in ATXN7L3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of ATXN7L3B. Does perturbing TMED2 lead to a significant change in ATXN7L3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
5013,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and THBS1 expression is observed. Does this perturbation lead to a significant difference in THBS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and THBS1 expression is observed. Does this perturbation lead to a significant difference in THBS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of CYP17A1-AS1. Does this perturbation cause a significant change in CYP17A1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of CYP17A1-AS1. Does this perturbation cause a significant change in CYP17A1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of IL2RB. Does this perturbation cause a significant change in IL2RB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of IL2RB. Does this perturbation cause a significant change in IL2RB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of IL2RB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of IL2RB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of TNFRSF10B. Does this perturbation cause a significant change in TNFRSF10B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of TNFRSF10B. Does this perturbation cause a significant change in TNFRSF10B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of LRRC4B. Does perturbing DERL2 lead to a significant change in LRRC4B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of LRRC4B. Does perturbing DERL2 lead to a significant change in LRRC4B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and KCNQ1OT1 expression is measured. Determine whether KCNQ1OT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and KCNQ1OT1 expression is measured. Determine whether KCNQ1OT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and RP11-304M2.5 expression is measured. Determine whether RP11-304M2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and RP11-304M2.5 expression is measured. Determine whether RP11-304M2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1598,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor LBX1 expression. Decide whether this perturbation leads to a significant alteration in LBX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor LBX1 expression. Decide whether this perturbation leads to a significant alteration in LBX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and RASGRP2 expression is quantified. Does this perturbation result in a significant change in RASGRP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and RASGRP2 expression is quantified. Does this perturbation result in a significant change in RASGRP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4040,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of SNHG7 is measured. Does this perturbation cause a significant change in SNHG7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of SNHG7 is measured. Does this perturbation cause a significant change in SNHG7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and ARHGDIB expression is quantified. Does this perturbation result in a significant change in ARHGDIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and ARHGDIB expression is quantified. Does this perturbation result in a significant change in ARHGDIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of PCF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of PCF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of RGS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of RGS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in RP11-15E18.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in RP11-15E18.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
173,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and TKTL1 expression is observed. Does this perturbation lead to a significant difference in TKTL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and TKTL1 expression is observed. Does this perturbation lead to a significant difference in TKTL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of PELO indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of PELO indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
928,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor SPAST expression. Decide whether this perturbation leads to a significant alteration in SPAST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor SPAST expression. Decide whether this perturbation leads to a significant alteration in SPAST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and KIF4A expression is measured. Determine whether KIF4A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and KIF4A expression is measured. Determine whether KIF4A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and AC012594.1 expression is quantified. Does this perturbation result in a significant change in AC012594.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and AC012594.1 expression is quantified. Does this perturbation result in a significant change in AC012594.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and RPL39 expression is measured. Determine whether RPL39 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and RPL39 expression is measured. Determine whether RPL39 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
17,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of P4HA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of P4HA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of SLC27A2. Does this perturbation cause a significant change in SLC27A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of SLC27A2. Does this perturbation cause a significant change in SLC27A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and TNFRSF10B expression is quantified. Does this perturbation result in a significant change in TNFRSF10B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and TNFRSF10B expression is quantified. Does this perturbation result in a significant change in TNFRSF10B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of PTPRC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of PTPRC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of CTBS. Does this perturbation cause a significant change in CTBS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of CTBS. Does this perturbation cause a significant change in CTBS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of VIM-AS1 is measured. Determine whether VIM-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of VIM-AS1 is measured. Determine whether VIM-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2218,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor ACSM3 expression. Decide whether this perturbation leads to a significant alteration in ACSM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor ACSM3 expression. Decide whether this perturbation leads to a significant alteration in ACSM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RGS20. Does this perturbation cause a significant change in RGS20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RGS20. Does this perturbation cause a significant change in RGS20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1940,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of GLG1 is measured. Does this perturbation cause a significant change in GLG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of GLG1 is measured. Does this perturbation cause a significant change in GLG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and LINC00938 expression is quantified. Does this perturbation result in a significant change in LINC00938 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and LINC00938 expression is quantified. Does this perturbation result in a significant change in LINC00938 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2683,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and KCTD19 expression is observed. Does this perturbation lead to a significant difference in KCTD19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and KCTD19 expression is observed. Does this perturbation lead to a significant difference in KCTD19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and FCGRT expression is measured. Determine whether FCGRT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and FCGRT expression is measured. Determine whether FCGRT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of SPAST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of SPAST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of AP000688.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of AP000688.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
700,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of UQCRB is measured. Does this perturbation cause a significant change in UQCRB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of UQCRB is measured. Does this perturbation cause a significant change in UQCRB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and RP11-38P22.2 expression is quantified. Does this perturbation result in a significant change in RP11-38P22.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and RP11-38P22.2 expression is quantified. Does this perturbation result in a significant change in RP11-38P22.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1708,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor UBE2V1 expression. Decide whether this perturbation leads to a significant alteration in UBE2V1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor UBE2V1 expression. Decide whether this perturbation leads to a significant alteration in UBE2V1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4370,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of RP11-181G12.2 is measured. Does this perturbation cause a significant change in RP11-181G12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of RP11-181G12.2 is measured. Does this perturbation cause a significant change in RP11-181G12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and SOBP expression is measured. Determine whether SOBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and SOBP expression is measured. Determine whether SOBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
220,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of CASP8 is measured. Does this perturbation cause a significant change in CASP8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of CASP8 is measured. Does this perturbation cause a significant change in CASP8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in RP11-445H22.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in RP11-445H22.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and LTB expression is measured. Determine whether LTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and LTB expression is measured. Determine whether LTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1268,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor HOTAIRM1 expression. Decide whether this perturbation leads to a significant alteration in HOTAIRM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor HOTAIRM1 expression. Decide whether this perturbation leads to a significant alteration in HOTAIRM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
508,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor PTPN11 expression. Decide whether this perturbation leads to a significant alteration in PTPN11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor PTPN11 expression. Decide whether this perturbation leads to a significant alteration in PTPN11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ARHGAP6. Does this perturbation cause a significant change in ARHGAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ARHGAP6. Does this perturbation cause a significant change in ARHGAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in RP11-360L9.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in RP11-360L9.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and PPP1R16B expression is measured. Determine whether PPP1R16B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and PPP1R16B expression is measured. Determine whether PPP1R16B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
55,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in C6orf48 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in C6orf48 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1003,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and RP11-334C17.5 expression is observed. Does this perturbation lead to a significant difference in RP11-334C17.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and RP11-334C17.5 expression is observed. Does this perturbation lead to a significant difference in RP11-334C17.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and ANKRD11 expression is measured. Determine whether ANKRD11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and ANKRD11 expression is measured. Determine whether ANKRD11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1418,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor NOXA1 expression. Decide whether this perturbation leads to a significant alteration in NOXA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor NOXA1 expression. Decide whether this perturbation leads to a significant alteration in NOXA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in MANF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in MANF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of AC015987.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of AC015987.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of RDH10. Does perturbing BHLHE40 lead to a significant change in RDH10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of RDH10. Does perturbing BHLHE40 lead to a significant change in RDH10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2438,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor RP13-216E22.4 expression. Decide whether this perturbation leads to a significant alteration in RP13-216E22.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor RP13-216E22.4 expression. Decide whether this perturbation leads to a significant alteration in RP13-216E22.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of REST is measured. Determine whether REST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of REST is measured. Determine whether REST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4808,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor EIF3A expression. Decide whether this perturbation leads to a significant alteration in EIF3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor EIF3A expression. Decide whether this perturbation leads to a significant alteration in EIF3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of RP11-573D15.9. Does this perturbation cause a significant change in RP11-573D15.9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of RP11-573D15.9. Does this perturbation cause a significant change in RP11-573D15.9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of LINC00657. Does perturbing OST4 lead to a significant change in LINC00657 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of LINC00657. Does perturbing OST4 lead to a significant change in LINC00657 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1390,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of NUF2 is measured. Does this perturbation cause a significant change in NUF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of NUF2 is measured. Does this perturbation cause a significant change in NUF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in DST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in DST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of TRAPPC10. Does this perturbation cause a significant change in TRAPPC10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of TRAPPC10. Does this perturbation cause a significant change in TRAPPC10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in LTN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in LTN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and EPB42 expression is quantified. Does this perturbation result in a significant change in EPB42 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and EPB42 expression is quantified. Does this perturbation result in a significant change in EPB42 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of PSORS1C1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of PSORS1C1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of LIMS1 is measured. Determine whether LIMS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of LIMS1 is measured. Determine whether LIMS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of DNTTIP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of DNTTIP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of LDLR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of LDLR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
33,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and CASP4 expression is observed. Does this perturbation lead to a significant difference in CASP4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and CASP4 expression is observed. Does this perturbation lead to a significant difference in CASP4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1073,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and ADAMTS10 expression is observed. Does this perturbation lead to a significant difference in ADAMTS10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and ADAMTS10 expression is observed. Does this perturbation lead to a significant difference in ADAMTS10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2430,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of RP13-216E22.4 is measured. Does this perturbation cause a significant change in RP13-216E22.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of RP13-216E22.4 is measured. Does this perturbation cause a significant change in RP13-216E22.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2068,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor RTN2 expression. Decide whether this perturbation leads to a significant alteration in RTN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor RTN2 expression. Decide whether this perturbation leads to a significant alteration in RTN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of BOLA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of BOLA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2070,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of MANF is measured. Does this perturbation cause a significant change in MANF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of MANF is measured. Does this perturbation cause a significant change in MANF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4593,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and LINC00862 expression is observed. Does this perturbation lead to a significant difference in LINC00862 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and LINC00862 expression is observed. Does this perturbation lead to a significant difference in LINC00862 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of P4HB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of P4HB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
37,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of CASP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of CASP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4013,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and DNMBP expression is observed. Does this perturbation lead to a significant difference in DNMBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and DNMBP expression is observed. Does this perturbation lead to a significant difference in DNMBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of THBS1 is measured. Determine whether THBS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of THBS1 is measured. Determine whether THBS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1183,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and SETD5-AS1 expression is observed. Does this perturbation lead to a significant difference in SETD5-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and SETD5-AS1 expression is observed. Does this perturbation lead to a significant difference in SETD5-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2990,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of CTD-2521M24.9 is measured. Does this perturbation cause a significant change in CTD-2521M24.9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of CTD-2521M24.9 is measured. Does this perturbation cause a significant change in CTD-2521M24.9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5060,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of PCF11 is measured. Does this perturbation cause a significant change in PCF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of PCF11 is measured. Does this perturbation cause a significant change in PCF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in RP11-132A1.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in RP11-132A1.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in ZC3H7A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in ZC3H7A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of S100A10 is measured. Determine whether S100A10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of S100A10 is measured. Determine whether S100A10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of LINC00657. Does this perturbation cause a significant change in LINC00657 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of LINC00657. Does this perturbation cause a significant change in LINC00657 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1163,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and KDM1B expression is observed. Does this perturbation lead to a significant difference in KDM1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and KDM1B expression is observed. Does this perturbation lead to a significant difference in KDM1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4268,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor RASGRP2 expression. Decide whether this perturbation leads to a significant alteration in RASGRP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor RASGRP2 expression. Decide whether this perturbation leads to a significant alteration in RASGRP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and RP11-838N2.4 expression is quantified. Does this perturbation result in a significant change in RP11-838N2.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and RP11-838N2.4 expression is quantified. Does this perturbation result in a significant change in RP11-838N2.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1263,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and HOTAIRM1 expression is observed. Does this perturbation lead to a significant difference in HOTAIRM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and HOTAIRM1 expression is observed. Does this perturbation lead to a significant difference in HOTAIRM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in RP11-157D23.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in RP11-157D23.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
97,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RP11-141B14.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RP11-141B14.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of BAMBI. Does perturbing QARS lead to a significant change in BAMBI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of BAMBI. Does perturbing QARS lead to a significant change in BAMBI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of CENPF. Does this perturbation cause a significant change in CENPF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of CENPF. Does this perturbation cause a significant change in CENPF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and RP11-2H8.2 expression is quantified. Does this perturbation result in a significant change in RP11-2H8.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and RP11-2H8.2 expression is quantified. Does this perturbation result in a significant change in RP11-2H8.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3678,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor ZC3H7A expression. Decide whether this perturbation leads to a significant alteration in ZC3H7A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor ZC3H7A expression. Decide whether this perturbation leads to a significant alteration in ZC3H7A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of PSMC1. Does perturbing SEC61B lead to a significant change in PSMC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of PSMC1. Does perturbing SEC61B lead to a significant change in PSMC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of KCNE3. Does this perturbation cause a significant change in KCNE3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of KCNE3. Does this perturbation cause a significant change in KCNE3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of NPAT is measured. Determine whether NPAT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of NPAT is measured. Determine whether NPAT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and ITGB2 expression is measured. Determine whether ITGB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and ITGB2 expression is measured. Determine whether ITGB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1030,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of TLN1 is measured. Does this perturbation cause a significant change in TLN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of TLN1 is measured. Does this perturbation cause a significant change in TLN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
620,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of SAMM50 is measured. Does this perturbation cause a significant change in SAMM50 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of SAMM50 is measured. Does this perturbation cause a significant change in SAMM50 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3138,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor LTN1 expression. Decide whether this perturbation leads to a significant alteration in LTN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor LTN1 expression. Decide whether this perturbation leads to a significant alteration in LTN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of JUND. Does this perturbation cause a significant change in JUND expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of JUND. Does this perturbation cause a significant change in JUND expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and PIK3R3 expression is quantified. Does this perturbation result in a significant change in PIK3R3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and PIK3R3 expression is quantified. Does this perturbation result in a significant change in PIK3R3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of IFT27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of IFT27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of RP11-328J2.1. Does perturbing SOCS1 lead to a significant change in RP11-328J2.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of RP11-328J2.1. Does perturbing SOCS1 lead to a significant change in RP11-328J2.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and LIMS1 expression is quantified. Does this perturbation result in a significant change in LIMS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and LIMS1 expression is quantified. Does this perturbation result in a significant change in LIMS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
260,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of DOK3 is measured. Does this perturbation cause a significant change in DOK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of DOK3 is measured. Does this perturbation cause a significant change in DOK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in ADAMTS10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in ADAMTS10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and CHST12 expression is quantified. Does this perturbation result in a significant change in CHST12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and CHST12 expression is quantified. Does this perturbation result in a significant change in CHST12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in CENPF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in CENPF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ARHGAP6 expression is measured. Determine whether ARHGAP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ARHGAP6 expression is measured. Determine whether ARHGAP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and PDE4D expression is quantified. Does this perturbation result in a significant change in PDE4D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and PDE4D expression is quantified. Does this perturbation result in a significant change in PDE4D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and MYH7B expression is quantified. Does this perturbation result in a significant change in MYH7B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and MYH7B expression is quantified. Does this perturbation result in a significant change in MYH7B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and LINC01031 expression is measured. Determine whether LINC01031 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and LINC01031 expression is measured. Determine whether LINC01031 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of PIK3R1 is measured. Determine whether PIK3R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of PIK3R1 is measured. Determine whether PIK3R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of RASGRP2. Does this perturbation cause a significant change in RASGRP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of RASGRP2. Does this perturbation cause a significant change in RASGRP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1698,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and LINC00862 expression is quantified. Does this perturbation result in a significant change in LINC00862 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and LINC00862 expression is quantified. Does this perturbation result in a significant change in LINC00862 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and CD9 expression is measured. Determine whether CD9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and CD9 expression is measured. Determine whether CD9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and CLDN11 expression is quantified. Does this perturbation result in a significant change in CLDN11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and CLDN11 expression is quantified. Does this perturbation result in a significant change in CLDN11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of RDH10 is measured. Determine whether RDH10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of RDH10 is measured. Determine whether RDH10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of TACC3. Does perturbing CAD lead to a significant change in TACC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of TACC3. Does perturbing CAD lead to a significant change in TACC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of RP11-471M2.3 is measured. Determine whether RP11-471M2.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of RP11-471M2.3 is measured. Determine whether RP11-471M2.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of ERV3-1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of ERV3-1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of SDF4 is measured. Determine whether SDF4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of SDF4 is measured. Determine whether SDF4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RP11-65L19.4 expression is quantified. Does this perturbation result in a significant change in RP11-65L19.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RP11-65L19.4 expression is quantified. Does this perturbation result in a significant change in RP11-65L19.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in CTD-2020K17.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in CTD-2020K17.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3830,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of PLA2G15 is measured. Does this perturbation cause a significant change in PLA2G15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of PLA2G15 is measured. Does this perturbation cause a significant change in PLA2G15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in CPQ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in CPQ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and PPP4R2 expression is measured. Determine whether PPP4R2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and PPP4R2 expression is measured. Determine whether PPP4R2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4550,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of CTC-550B14.7 is measured. Does this perturbation cause a significant change in CTC-550B14.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of CTC-550B14.7 is measured. Does this perturbation cause a significant change in CTC-550B14.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of TMEM60. Does this perturbation cause a significant change in TMEM60 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of TMEM60. Does this perturbation cause a significant change in TMEM60 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and ANPEP expression is quantified. Does this perturbation result in a significant change in ANPEP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and ANPEP expression is quantified. Does this perturbation result in a significant change in ANPEP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4413,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and AC005540.3 expression is observed. Does this perturbation lead to a significant difference in AC005540.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and AC005540.3 expression is observed. Does this perturbation lead to a significant difference in AC005540.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
42,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and LPAR5 expression is quantified. Does this perturbation result in a significant change in LPAR5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and LPAR5 expression is quantified. Does this perturbation result in a significant change in LPAR5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of ZMYND8. Does perturbing SEL1L lead to a significant change in ZMYND8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of ZMYND8. Does perturbing SEL1L lead to a significant change in ZMYND8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and NXF1 expression is quantified. Does this perturbation result in a significant change in NXF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and NXF1 expression is quantified. Does this perturbation result in a significant change in NXF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and SLFNL1 expression is quantified. Does this perturbation result in a significant change in SLFNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and SLFNL1 expression is quantified. Does this perturbation result in a significant change in SLFNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4858,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor STK17B expression. Decide whether this perturbation leads to a significant alteration in STK17B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor STK17B expression. Decide whether this perturbation leads to a significant alteration in STK17B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4630,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of BOLA3 is measured. Does this perturbation cause a significant change in BOLA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of BOLA3 is measured. Does this perturbation cause a significant change in BOLA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of NPAT. Does this perturbation cause a significant change in NPAT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of NPAT. Does this perturbation cause a significant change in NPAT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4473,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and RP11-95O2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-95O2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and RP11-95O2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-95O2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of PAXBP1. Does perturbing DNAJC19 lead to a significant change in PAXBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of PAXBP1. Does perturbing DNAJC19 lead to a significant change in PAXBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of FCGRT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of FCGRT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4723,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and RP11-322J23.1 expression is observed. Does this perturbation lead to a significant difference in RP11-322J23.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and RP11-322J23.1 expression is observed. Does this perturbation lead to a significant difference in RP11-322J23.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of NTRK1. Does perturbing CCND3 lead to a significant change in NTRK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of NTRK1. Does perturbing CCND3 lead to a significant change in NTRK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and BAMBI expression is measured. Determine whether BAMBI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and BAMBI expression is measured. Determine whether BAMBI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of RP11-254F7.4. Does this perturbation cause a significant change in RP11-254F7.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of RP11-254F7.4. Does this perturbation cause a significant change in RP11-254F7.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and RP3-465N24.6 expression is quantified. Does this perturbation result in a significant change in RP3-465N24.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and RP3-465N24.6 expression is quantified. Does this perturbation result in a significant change in RP3-465N24.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2558,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor MORC2-AS1 expression. Decide whether this perturbation leads to a significant alteration in MORC2-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor MORC2-AS1 expression. Decide whether this perturbation leads to a significant alteration in MORC2-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
330,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of PCK2 is measured. Does this perturbation cause a significant change in PCK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of PCK2 is measured. Does this perturbation cause a significant change in PCK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of RP11-789C1.1. Does this perturbation cause a significant change in RP11-789C1.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of RP11-789C1.1. Does this perturbation cause a significant change in RP11-789C1.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1713,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and EPB42 expression is observed. Does this perturbation lead to a significant difference in EPB42 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and EPB42 expression is observed. Does this perturbation lead to a significant difference in EPB42 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and ZMYND8 expression is measured. Determine whether ZMYND8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and ZMYND8 expression is measured. Determine whether ZMYND8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1008,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor RP11-334C17.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-334C17.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor RP11-334C17.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-334C17.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of RGS20. Does perturbing ARHGAP22 lead to a significant change in RGS20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of RGS20. Does perturbing ARHGAP22 lead to a significant change in RGS20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in CDCA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in CDCA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
593,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and PPP1R16B expression is observed. Does this perturbation lead to a significant difference in PPP1R16B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and PPP1R16B expression is observed. Does this perturbation lead to a significant difference in PPP1R16B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and CD83 expression is quantified. Does this perturbation result in a significant change in CD83 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and CD83 expression is quantified. Does this perturbation result in a significant change in CD83 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of CCDC69. Does perturbing KCTD16 lead to a significant change in CCDC69 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of CCDC69. Does perturbing KCTD16 lead to a significant change in CCDC69 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of GNPTG. Does this perturbation cause a significant change in GNPTG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of GNPTG. Does this perturbation cause a significant change in GNPTG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in CYP17A1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in CYP17A1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1828,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor DDIT4 expression. Decide whether this perturbation leads to a significant alteration in DDIT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor DDIT4 expression. Decide whether this perturbation leads to a significant alteration in DDIT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of ACRV1 is measured. Determine whether ACRV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of ACRV1 is measured. Determine whether ACRV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in PCF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in PCF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3363,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and SETX expression is observed. Does this perturbation lead to a significant difference in SETX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and SETX expression is observed. Does this perturbation lead to a significant difference in SETX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and HLTF expression is quantified. Does this perturbation result in a significant change in HLTF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and HLTF expression is quantified. Does this perturbation result in a significant change in HLTF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4023,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and PIK3R3 expression is observed. Does this perturbation lead to a significant difference in PIK3R3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and PIK3R3 expression is observed. Does this perturbation lead to a significant difference in PIK3R3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
610,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of HP1BP3 is measured. Does this perturbation cause a significant change in HP1BP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of HP1BP3 is measured. Does this perturbation cause a significant change in HP1BP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of RP11-423O2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of RP11-423O2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of MED13. Does perturbing AARS lead to a significant change in MED13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of MED13. Does perturbing AARS lead to a significant change in MED13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and DUSP21 expression is measured. Determine whether DUSP21 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and DUSP21 expression is measured. Determine whether DUSP21 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of SAMM50 is measured. Determine whether SAMM50 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of SAMM50 is measured. Determine whether SAMM50 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2563,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and SBF2 expression is observed. Does this perturbation lead to a significant difference in SBF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and SBF2 expression is observed. Does this perturbation lead to a significant difference in SBF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of SOBP is measured. Determine whether SOBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of SOBP is measured. Determine whether SOBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of HIST1H2AM is measured. Determine whether HIST1H2AM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of HIST1H2AM is measured. Determine whether HIST1H2AM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3483,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and PTGS1 expression is observed. Does this perturbation lead to a significant difference in PTGS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and PTGS1 expression is observed. Does this perturbation lead to a significant difference in PTGS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4580,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of VIMP is measured. Does this perturbation cause a significant change in VIMP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of VIMP is measured. Does this perturbation cause a significant change in VIMP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and AC008074.3 expression is measured. Determine whether AC008074.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and AC008074.3 expression is measured. Determine whether AC008074.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of IL32. Does this perturbation cause a significant change in IL32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of IL32. Does this perturbation cause a significant change in IL32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4763,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and TLK2 expression is observed. Does this perturbation lead to a significant difference in TLK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and TLK2 expression is observed. Does this perturbation lead to a significant difference in TLK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1058,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor RP11-38P22.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-38P22.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor RP11-38P22.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-38P22.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1240,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of CYP17A1-AS1 is measured. Does this perturbation cause a significant change in CYP17A1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of CYP17A1-AS1 is measured. Does this perturbation cause a significant change in CYP17A1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ZXDA is measured. Determine whether ZXDA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ZXDA is measured. Determine whether ZXDA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and SLC27A2 expression is measured. Determine whether SLC27A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and SLC27A2 expression is measured. Determine whether SLC27A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in ESCO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in ESCO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and POLR2J3 expression is quantified. Does this perturbation result in a significant change in POLR2J3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and POLR2J3 expression is quantified. Does this perturbation result in a significant change in POLR2J3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of NRIP1. Does perturbing BHLHE40 lead to a significant change in NRIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of NRIP1. Does perturbing BHLHE40 lead to a significant change in NRIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in PSMC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in PSMC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in DNTTIP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in DNTTIP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and SETD5-AS1 expression is quantified. Does this perturbation result in a significant change in SETD5-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and SETD5-AS1 expression is quantified. Does this perturbation result in a significant change in SETD5-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in TMEM60 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in TMEM60 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and PPM1N expression is measured. Determine whether PPM1N exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and PPM1N expression is measured. Determine whether PPM1N exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and KDM1B expression is measured. Determine whether KDM1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and KDM1B expression is measured. Determine whether KDM1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2403,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and P4HA2 expression is observed. Does this perturbation lead to a significant difference in P4HA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and P4HA2 expression is observed. Does this perturbation lead to a significant difference in P4HA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of QSER1. Does this perturbation cause a significant change in QSER1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of QSER1. Does this perturbation cause a significant change in QSER1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
180,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of STC2 is measured. Does this perturbation cause a significant change in STC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of STC2 is measured. Does this perturbation cause a significant change in STC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and LINC00657 expression is quantified. Does this perturbation result in a significant change in LINC00657 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and LINC00657 expression is quantified. Does this perturbation result in a significant change in LINC00657 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of SRP72. Does this perturbation cause a significant change in SRP72 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of SRP72. Does this perturbation cause a significant change in SRP72 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4003,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and IL2RB expression is observed. Does this perturbation lead to a significant difference in IL2RB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and IL2RB expression is observed. Does this perturbation lead to a significant difference in IL2RB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of AC018878.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of AC018878.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
64,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RIOK3. Does this perturbation cause a significant change in RIOK3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RIOK3. Does this perturbation cause a significant change in RIOK3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in AC005540.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in AC005540.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
31,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of CASP4. Does perturbing CREB1 lead to a significant change in CASP4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of CASP4. Does perturbing CREB1 lead to a significant change in CASP4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3170,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of MLEC is measured. Does this perturbation cause a significant change in MLEC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of MLEC is measured. Does this perturbation cause a significant change in MLEC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and MEX3B expression is quantified. Does this perturbation result in a significant change in MEX3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and MEX3B expression is quantified. Does this perturbation result in a significant change in MEX3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of RP11-132A1.4 is measured. Determine whether RP11-132A1.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of RP11-132A1.4 is measured. Determine whether RP11-132A1.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of KHDC1L is measured. Determine whether KHDC1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of KHDC1L is measured. Determine whether KHDC1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of MEX3B. Does this perturbation cause a significant change in MEX3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of MEX3B. Does this perturbation cause a significant change in MEX3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of CTC-550B14.7 is measured. Determine whether CTC-550B14.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of CTC-550B14.7 is measured. Determine whether CTC-550B14.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4558,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor CTC-550B14.7 expression. Decide whether this perturbation leads to a significant alteration in CTC-550B14.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor CTC-550B14.7 expression. Decide whether this perturbation leads to a significant alteration in CTC-550B14.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of UBE3A. Does this perturbation cause a significant change in UBE3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of UBE3A. Does this perturbation cause a significant change in UBE3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in WDR72 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in WDR72 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of VAMP2. Does perturbing TARS lead to a significant change in VAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of VAMP2. Does perturbing TARS lead to a significant change in VAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of LTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of LTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of FYTTD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of FYTTD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in ASPM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in ASPM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in C19orf59 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in C19orf59 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and CLDN11 expression is measured. Determine whether CLDN11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and CLDN11 expression is measured. Determine whether CLDN11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of RP11-640M9.1 is measured. Determine whether RP11-640M9.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of RP11-640M9.1 is measured. Determine whether RP11-640M9.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and HP1BP3 expression is measured. Determine whether HP1BP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and HP1BP3 expression is measured. Determine whether HP1BP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in IFT27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in IFT27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of ATAD2B. Does this perturbation cause a significant change in ATAD2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of ATAD2B. Does this perturbation cause a significant change in ATAD2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2268,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor C6orf120 expression. Decide whether this perturbation leads to a significant alteration in C6orf120 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor C6orf120 expression. Decide whether this perturbation leads to a significant alteration in C6orf120 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of CTD-2521M24.9. Does perturbing ASCC3 lead to a significant change in CTD-2521M24.9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of CTD-2521M24.9. Does perturbing ASCC3 lead to a significant change in CTD-2521M24.9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2033,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and RP11-212I21.4 expression is observed. Does this perturbation lead to a significant difference in RP11-212I21.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and RP11-212I21.4 expression is observed. Does this perturbation lead to a significant difference in RP11-212I21.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5058,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor CFH expression. Decide whether this perturbation leads to a significant alteration in CFH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor CFH expression. Decide whether this perturbation leads to a significant alteration in CFH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and GRN expression is measured. Determine whether GRN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and GRN expression is measured. Determine whether GRN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5063,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and PCF11 expression is observed. Does this perturbation lead to a significant difference in PCF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and PCF11 expression is observed. Does this perturbation lead to a significant difference in PCF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of CTD-2020K17.1. Does perturbing COPB1 lead to a significant change in CTD-2020K17.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of CTD-2020K17.1. Does perturbing COPB1 lead to a significant change in CTD-2020K17.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of AC096559.1. Does this perturbation cause a significant change in AC096559.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of AC096559.1. Does this perturbation cause a significant change in AC096559.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of USP37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of USP37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
963,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and ZEB2 expression is observed. Does this perturbation lead to a significant difference in ZEB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and ZEB2 expression is observed. Does this perturbation lead to a significant difference in ZEB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of P4HA2 is measured. Determine whether P4HA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of P4HA2 is measured. Determine whether P4HA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
798,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor REST expression. Decide whether this perturbation leads to a significant alteration in REST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor REST expression. Decide whether this perturbation leads to a significant alteration in REST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4970,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of TMEM60 is measured. Does this perturbation cause a significant change in TMEM60 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of TMEM60 is measured. Does this perturbation cause a significant change in TMEM60 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3403,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and C3AR1 expression is observed. Does this perturbation lead to a significant difference in C3AR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and C3AR1 expression is observed. Does this perturbation lead to a significant difference in C3AR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in TNFRSF10B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in TNFRSF10B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and MED13 expression is measured. Determine whether MED13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and MED13 expression is measured. Determine whether MED13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of CMTM6. Does perturbing CARS lead to a significant change in CMTM6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of CMTM6. Does perturbing CARS lead to a significant change in CMTM6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of C1GALT1. Does perturbing GNPNAT1 lead to a significant change in C1GALT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of C1GALT1. Does perturbing GNPNAT1 lead to a significant change in C1GALT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RP11-65L19.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RP11-65L19.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and RP11-247A12.2 expression is quantified. Does this perturbation result in a significant change in RP11-247A12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and RP11-247A12.2 expression is quantified. Does this perturbation result in a significant change in RP11-247A12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of CLINT1. Does perturbing SRPR lead to a significant change in CLINT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of CLINT1. Does perturbing SRPR lead to a significant change in CLINT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of ZP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of ZP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in CDK13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in CDK13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of TOPBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of TOPBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4230,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of RP11-666A20.4 is measured. Does this perturbation cause a significant change in RP11-666A20.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of RP11-666A20.4 is measured. Does this perturbation cause a significant change in RP11-666A20.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4798,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor ANPEP expression. Decide whether this perturbation leads to a significant alteration in ANPEP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor ANPEP expression. Decide whether this perturbation leads to a significant alteration in ANPEP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and TTC18 expression is quantified. Does this perturbation result in a significant change in TTC18 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and TTC18 expression is quantified. Does this perturbation result in a significant change in TTC18 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of GPR146 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of GPR146 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1890,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of RP11-434H6.6 is measured. Does this perturbation cause a significant change in RP11-434H6.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of RP11-434H6.6 is measured. Does this perturbation cause a significant change in RP11-434H6.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of CLDN11. Does perturbing DHDDS lead to a significant change in CLDN11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of CLDN11. Does perturbing DHDDS lead to a significant change in CLDN11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of LDLR. Does perturbing IER3IP1 lead to a significant change in LDLR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of LDLR. Does perturbing IER3IP1 lead to a significant change in LDLR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
973,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and VIMP expression is observed. Does this perturbation lead to a significant difference in VIMP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and VIMP expression is observed. Does this perturbation lead to a significant difference in VIMP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in PITPNB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in PITPNB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and RP11-15E18.1 expression is measured. Determine whether RP11-15E18.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and RP11-15E18.1 expression is measured. Determine whether RP11-15E18.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5070,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of ERP29 is measured. Does this perturbation cause a significant change in ERP29 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of ERP29 is measured. Does this perturbation cause a significant change in ERP29 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
938,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor RP11-863K10.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-863K10.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor RP11-863K10.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-863K10.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
303,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and RP11-423O2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-423O2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and RP11-423O2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-423O2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1373,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and KCTD1 expression is observed. Does this perturbation lead to a significant difference in KCTD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and KCTD1 expression is observed. Does this perturbation lead to a significant difference in KCTD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2160,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of PDK2 is measured. Does this perturbation cause a significant change in PDK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of PDK2 is measured. Does this perturbation cause a significant change in PDK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and C19orf59 expression is quantified. Does this perturbation result in a significant change in C19orf59 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and C19orf59 expression is quantified. Does this perturbation result in a significant change in C19orf59 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in LINC00938 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in LINC00938 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in SETD5-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in SETD5-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of C12orf23 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of C12orf23 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3858,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor PHF21A expression. Decide whether this perturbation leads to a significant alteration in PHF21A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor PHF21A expression. Decide whether this perturbation leads to a significant alteration in PHF21A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and PELO expression is measured. Determine whether PELO exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and PELO expression is measured. Determine whether PELO exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
968,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor ZEB2 expression. Decide whether this perturbation leads to a significant alteration in ZEB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor ZEB2 expression. Decide whether this perturbation leads to a significant alteration in ZEB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in RP11-381O7.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in RP11-381O7.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and VAMP2 expression is measured. Determine whether VAMP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and VAMP2 expression is measured. Determine whether VAMP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3640,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of RP11-3D4.3 is measured. Does this perturbation cause a significant change in RP11-3D4.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of RP11-3D4.3 is measured. Does this perturbation cause a significant change in RP11-3D4.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
280,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of CDRT4 is measured. Does this perturbation cause a significant change in CDRT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of CDRT4 is measured. Does this perturbation cause a significant change in CDRT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of CHST12. Does this perturbation cause a significant change in CHST12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of CHST12. Does this perturbation cause a significant change in CHST12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and RP11-2H8.2 expression is measured. Determine whether RP11-2H8.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and RP11-2H8.2 expression is measured. Determine whether RP11-2H8.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and HIST1H1D expression is quantified. Does this perturbation result in a significant change in HIST1H1D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and HIST1H1D expression is quantified. Does this perturbation result in a significant change in HIST1H1D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and AC015987.2 expression is measured. Determine whether AC015987.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and AC015987.2 expression is measured. Determine whether AC015987.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and RTN2 expression is quantified. Does this perturbation result in a significant change in RTN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and RTN2 expression is quantified. Does this perturbation result in a significant change in RTN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1943,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and GLG1 expression is observed. Does this perturbation lead to a significant difference in GLG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and GLG1 expression is observed. Does this perturbation lead to a significant difference in GLG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and ASPM expression is quantified. Does this perturbation result in a significant change in ASPM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and ASPM expression is quantified. Does this perturbation result in a significant change in ASPM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of TTC32. Does this perturbation cause a significant change in TTC32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of TTC32. Does this perturbation cause a significant change in TTC32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
623,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and SAMM50 expression is observed. Does this perturbation lead to a significant difference in SAMM50 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and SAMM50 expression is observed. Does this perturbation lead to a significant difference in SAMM50 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and ATXN7L3B expression is quantified. Does this perturbation result in a significant change in ATXN7L3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and ATXN7L3B expression is quantified. Does this perturbation result in a significant change in ATXN7L3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in SOBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in SOBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of CLINT1 is measured. Determine whether CLINT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of CLINT1 is measured. Determine whether CLINT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4828,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor NFE2L3 expression. Decide whether this perturbation leads to a significant alteration in NFE2L3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor NFE2L3 expression. Decide whether this perturbation leads to a significant alteration in NFE2L3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
740,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of ANXA4 is measured. Does this perturbation cause a significant change in ANXA4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of ANXA4 is measured. Does this perturbation cause a significant change in ANXA4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of GOT1. Does this perturbation cause a significant change in GOT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of GOT1. Does this perturbation cause a significant change in GOT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and TUBA1C expression is measured. Determine whether TUBA1C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and TUBA1C expression is measured. Determine whether TUBA1C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of NCKAP1L is measured. Determine whether NCKAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of NCKAP1L is measured. Determine whether NCKAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and IL13RA1 expression is measured. Determine whether IL13RA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and IL13RA1 expression is measured. Determine whether IL13RA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4120,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of FOXO6 is measured. Does this perturbation cause a significant change in FOXO6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of FOXO6 is measured. Does this perturbation cause a significant change in FOXO6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3680,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of SLC27A2 is measured. Does this perturbation cause a significant change in SLC27A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of SLC27A2 is measured. Does this perturbation cause a significant change in SLC27A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RP11-65L19.4 is measured. Determine whether RP11-65L19.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RP11-65L19.4 is measured. Determine whether RP11-65L19.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of CDT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of CDT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
518,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor PDE4D expression. Decide whether this perturbation leads to a significant alteration in PDE4D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor PDE4D expression. Decide whether this perturbation leads to a significant alteration in PDE4D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in PDE3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in PDE3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5090,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of TGOLN2 is measured. Does this perturbation cause a significant change in TGOLN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of TGOLN2 is measured. Does this perturbation cause a significant change in TGOLN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1638,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor DNASE2 expression. Decide whether this perturbation leads to a significant alteration in DNASE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor DNASE2 expression. Decide whether this perturbation leads to a significant alteration in DNASE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
768,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor HLA-AS1 expression. Decide whether this perturbation leads to a significant alteration in HLA-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor HLA-AS1 expression. Decide whether this perturbation leads to a significant alteration in HLA-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and VIM-AS1 expression is measured. Determine whether VIM-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and VIM-AS1 expression is measured. Determine whether VIM-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1113,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and GOT1 expression is observed. Does this perturbation lead to a significant difference in GOT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and GOT1 expression is observed. Does this perturbation lead to a significant difference in GOT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of PIK3IP1. Does perturbing SEC61B lead to a significant change in PIK3IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of PIK3IP1. Does perturbing SEC61B lead to a significant change in PIK3IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in AP000688.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in AP000688.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and NBEAL2 expression is quantified. Does this perturbation result in a significant change in NBEAL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and NBEAL2 expression is quantified. Does this perturbation result in a significant change in NBEAL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of IDS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of IDS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of TFPI is measured. Determine whether TFPI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of TFPI is measured. Determine whether TFPI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of LINC00862. Does perturbing COPZ1 lead to a significant change in LINC00862 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of LINC00862. Does perturbing COPZ1 lead to a significant change in LINC00862 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2083,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and PGM3 expression is observed. Does this perturbation lead to a significant difference in PGM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and PGM3 expression is observed. Does this perturbation lead to a significant difference in PGM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of RP11-434H6.6. Does perturbing CAD lead to a significant change in RP11-434H6.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of RP11-434H6.6. Does perturbing CAD lead to a significant change in RP11-434H6.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of TTC18. Does this perturbation cause a significant change in TTC18 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of TTC18. Does this perturbation cause a significant change in TTC18 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1540,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of CTD-2267D19.3 is measured. Does this perturbation cause a significant change in CTD-2267D19.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of CTD-2267D19.3 is measured. Does this perturbation cause a significant change in CTD-2267D19.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2873,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and RGS3 expression is observed. Does this perturbation lead to a significant difference in RGS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and RGS3 expression is observed. Does this perturbation lead to a significant difference in RGS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of CPQ. Does this perturbation cause a significant change in CPQ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of CPQ. Does this perturbation cause a significant change in CPQ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of DST. Does perturbing SCYL1 lead to a significant change in DST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of DST. Does perturbing SCYL1 lead to a significant change in DST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in FOXO6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in FOXO6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of TRAPPC10 is measured. Determine whether TRAPPC10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of TRAPPC10 is measured. Determine whether TRAPPC10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2200,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of CST7 is measured. Does this perturbation cause a significant change in CST7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of CST7 is measured. Does this perturbation cause a significant change in CST7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of AC079466.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of AC079466.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4378,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor RP11-181G12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-181G12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor RP11-181G12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-181G12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2778,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor LAMP2 expression. Decide whether this perturbation leads to a significant alteration in LAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor LAMP2 expression. Decide whether this perturbation leads to a significant alteration in LAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of HPCAL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of HPCAL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of SAMM50. Does perturbing HARS lead to a significant change in SAMM50 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of SAMM50. Does perturbing HARS lead to a significant change in SAMM50 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1983,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and KLF3 expression is observed. Does this perturbation lead to a significant difference in KLF3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and KLF3 expression is observed. Does this perturbation lead to a significant difference in KLF3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2203,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and CST7 expression is observed. Does this perturbation lead to a significant difference in CST7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and CST7 expression is observed. Does this perturbation lead to a significant difference in CST7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of RP11-423O2.5. Does this perturbation cause a significant change in RP11-423O2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of RP11-423O2.5. Does this perturbation cause a significant change in RP11-423O2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of C9orf64 is measured. Determine whether C9orf64 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of C9orf64 is measured. Determine whether C9orf64 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of DSC2 is measured. Determine whether DSC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of DSC2 is measured. Determine whether DSC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in TMEM87B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in TMEM87B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of ZEB1 is measured. Determine whether ZEB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of ZEB1 is measured. Determine whether ZEB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
793,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and REST expression is observed. Does this perturbation lead to a significant difference in REST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and REST expression is observed. Does this perturbation lead to a significant difference in REST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of HLA-AS1. Does perturbing DAD1 lead to a significant change in HLA-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of HLA-AS1. Does perturbing DAD1 lead to a significant change in HLA-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of RP11-360L9.8 is measured. Determine whether RP11-360L9.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of RP11-360L9.8 is measured. Determine whether RP11-360L9.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
748,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor ANXA4 expression. Decide whether this perturbation leads to a significant alteration in ANXA4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor ANXA4 expression. Decide whether this perturbation leads to a significant alteration in ANXA4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4528,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor ATF7IP2 expression. Decide whether this perturbation leads to a significant alteration in ATF7IP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor ATF7IP2 expression. Decide whether this perturbation leads to a significant alteration in ATF7IP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1500,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of ZNF292 is measured. Does this perturbation cause a significant change in ZNF292 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of ZNF292 is measured. Does this perturbation cause a significant change in ZNF292 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in RPL39 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in RPL39 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in PDE9A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in PDE9A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and RP11-573D15.9 expression is quantified. Does this perturbation result in a significant change in RP11-573D15.9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and RP11-573D15.9 expression is quantified. Does this perturbation result in a significant change in RP11-573D15.9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of NUFIP2. Does perturbing GBF1 lead to a significant change in NUFIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of NUFIP2. Does perturbing GBF1 lead to a significant change in NUFIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of CTSF is measured. Determine whether CTSF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of CTSF is measured. Determine whether CTSF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of TUBA1C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of TUBA1C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and IFT27 expression is quantified. Does this perturbation result in a significant change in IFT27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and IFT27 expression is quantified. Does this perturbation result in a significant change in IFT27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and TTC32 expression is measured. Determine whether TTC32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and TTC32 expression is measured. Determine whether TTC32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of BAMBI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of BAMBI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of GALNT7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of GALNT7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of AC008074.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of AC008074.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and ATF6 expression is quantified. Does this perturbation result in a significant change in ATF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and ATF6 expression is quantified. Does this perturbation result in a significant change in ATF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and UBE2V1 expression is quantified. Does this perturbation result in a significant change in UBE2V1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and UBE2V1 expression is quantified. Does this perturbation result in a significant change in UBE2V1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2823,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and PSMC1 expression is observed. Does this perturbation lead to a significant difference in PSMC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and PSMC1 expression is observed. Does this perturbation lead to a significant difference in PSMC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4813,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and MBNL1 expression is observed. Does this perturbation lead to a significant difference in MBNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and MBNL1 expression is observed. Does this perturbation lead to a significant difference in MBNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of CLDN11. Does this perturbation cause a significant change in CLDN11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of CLDN11. Does this perturbation cause a significant change in CLDN11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of GDF11 is measured. Determine whether GDF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of GDF11 is measured. Determine whether GDF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of LAMP2 is measured. Determine whether LAMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of LAMP2 is measured. Determine whether LAMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4830,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of RP11-390B4.5 is measured. Does this perturbation cause a significant change in RP11-390B4.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of RP11-390B4.5 is measured. Does this perturbation cause a significant change in RP11-390B4.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
78,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor CEBPG expression. Decide whether this perturbation leads to a significant alteration in CEBPG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor CEBPG expression. Decide whether this perturbation leads to a significant alteration in CEBPG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1523,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and ZMYND8 expression is observed. Does this perturbation lead to a significant difference in ZMYND8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and ZMYND8 expression is observed. Does this perturbation lead to a significant difference in ZMYND8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2118,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor PELO expression. Decide whether this perturbation leads to a significant alteration in PELO expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor PELO expression. Decide whether this perturbation leads to a significant alteration in PELO expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and NRIP1 expression is quantified. Does this perturbation result in a significant change in NRIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and NRIP1 expression is quantified. Does this perturbation result in a significant change in NRIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and P4HB expression is quantified. Does this perturbation result in a significant change in P4HB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and P4HB expression is quantified. Does this perturbation result in a significant change in P4HB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1318,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor SNHG10 expression. Decide whether this perturbation leads to a significant alteration in SNHG10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor SNHG10 expression. Decide whether this perturbation leads to a significant alteration in SNHG10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1353,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and TAGLN expression is observed. Does this perturbation lead to a significant difference in TAGLN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and TAGLN expression is observed. Does this perturbation lead to a significant difference in TAGLN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and PELO expression is measured. Determine whether PELO exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and PELO expression is measured. Determine whether PELO exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1140,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of SP100 is measured. Does this perturbation cause a significant change in SP100 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of SP100 is measured. Does this perturbation cause a significant change in SP100 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and DKFZP779L1853 expression is measured. Determine whether DKFZP779L1853 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and DKFZP779L1853 expression is measured. Determine whether DKFZP779L1853 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and ATP6AP2 expression is quantified. Does this perturbation result in a significant change in ATP6AP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and ATP6AP2 expression is quantified. Does this perturbation result in a significant change in ATP6AP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of ADAMTS10 is measured. Determine whether ADAMTS10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of ADAMTS10 is measured. Determine whether ADAMTS10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in ZNF280B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in ZNF280B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2253,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and AC015987.1 expression is observed. Does this perturbation lead to a significant difference in AC015987.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and AC015987.1 expression is observed. Does this perturbation lead to a significant difference in AC015987.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of CENPC. Does perturbing DERL2 lead to a significant change in CENPC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of CENPC. Does perturbing DERL2 lead to a significant change in CENPC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and TMEM60 expression is measured. Determine whether TMEM60 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and TMEM60 expression is measured. Determine whether TMEM60 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of ACSM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of ACSM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
443,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and NCKAP1L expression is observed. Does this perturbation lead to a significant difference in NCKAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and NCKAP1L expression is observed. Does this perturbation lead to a significant difference in NCKAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of ACE. Does this perturbation cause a significant change in ACE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of ACE. Does this perturbation cause a significant change in ACE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and ATF7IP2 expression is measured. Determine whether ATF7IP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and ATF7IP2 expression is measured. Determine whether ATF7IP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of C19orf59 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of C19orf59 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and CTD-2587M2.1 expression is measured. Determine whether CTD-2587M2.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and CTD-2587M2.1 expression is measured. Determine whether CTD-2587M2.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and WDR72 expression is quantified. Does this perturbation result in a significant change in WDR72 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and WDR72 expression is quantified. Does this perturbation result in a significant change in WDR72 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of DDX6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of DDX6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of RP11-90P5.2. Does perturbing EIF2B4 lead to a significant change in RP11-90P5.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of RP11-90P5.2. Does perturbing EIF2B4 lead to a significant change in RP11-90P5.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1850,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of TRAPPC10 is measured. Does this perturbation cause a significant change in TRAPPC10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of TRAPPC10 is measured. Does this perturbation cause a significant change in TRAPPC10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of HIST1H1D. Does perturbing SRPRB lead to a significant change in HIST1H1D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of HIST1H1D. Does perturbing SRPRB lead to a significant change in HIST1H1D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and AFF1 expression is quantified. Does this perturbation result in a significant change in AFF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and AFF1 expression is quantified. Does this perturbation result in a significant change in AFF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of CYP17A1-AS1. Does perturbing DDRGK1 lead to a significant change in CYP17A1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of CYP17A1-AS1. Does perturbing DDRGK1 lead to a significant change in CYP17A1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
193,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and PDE9A expression is observed. Does this perturbation lead to a significant difference in PDE9A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and PDE9A expression is observed. Does this perturbation lead to a significant difference in PDE9A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
128,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor NRIP1 expression. Decide whether this perturbation leads to a significant alteration in NRIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor NRIP1 expression. Decide whether this perturbation leads to a significant alteration in NRIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and ATP5EP2 expression is measured. Determine whether ATP5EP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and ATP5EP2 expression is measured. Determine whether ATP5EP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of H1FX. Does this perturbation cause a significant change in H1FX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of H1FX. Does this perturbation cause a significant change in H1FX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and HM13 expression is measured. Determine whether HM13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and HM13 expression is measured. Determine whether HM13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of DYNC1H1. Does this perturbation cause a significant change in DYNC1H1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of DYNC1H1. Does this perturbation cause a significant change in DYNC1H1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of STARD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of STARD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
548,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor PCF11 expression. Decide whether this perturbation leads to a significant alteration in PCF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor PCF11 expression. Decide whether this perturbation leads to a significant alteration in PCF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3230,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of RP11-16E12.1 is measured. Does this perturbation cause a significant change in RP11-16E12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of RP11-16E12.1 is measured. Does this perturbation cause a significant change in RP11-16E12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1238,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor SRP72 expression. Decide whether this perturbation leads to a significant alteration in SRP72 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor SRP72 expression. Decide whether this perturbation leads to a significant alteration in SRP72 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in TOPBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in TOPBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of NTRK1 is measured. Determine whether NTRK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of NTRK1 is measured. Determine whether NTRK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3380,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of TRIM38 is measured. Does this perturbation cause a significant change in TRIM38 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of TRIM38 is measured. Does this perturbation cause a significant change in TRIM38 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and AC096559.1 expression is measured. Determine whether AC096559.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and AC096559.1 expression is measured. Determine whether AC096559.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of SLBP. Does perturbing SLC39A7 lead to a significant change in SLBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of SLBP. Does perturbing SLC39A7 lead to a significant change in SLBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2590,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of RP11-471M2.3 is measured. Does this perturbation cause a significant change in RP11-471M2.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of RP11-471M2.3 is measured. Does this perturbation cause a significant change in RP11-471M2.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of MT2A is measured. Determine whether MT2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of MT2A is measured. Determine whether MT2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in PELO expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in PELO expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3398,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor TUBA1C expression. Decide whether this perturbation leads to a significant alteration in TUBA1C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor TUBA1C expression. Decide whether this perturbation leads to a significant alteration in TUBA1C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1988,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor KLF3 expression. Decide whether this perturbation leads to a significant alteration in KLF3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor KLF3 expression. Decide whether this perturbation leads to a significant alteration in KLF3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of ACSM3. Does this perturbation cause a significant change in ACSM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of ACSM3. Does this perturbation cause a significant change in ACSM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3370,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of LIMS1 is measured. Does this perturbation cause a significant change in LIMS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of LIMS1 is measured. Does this perturbation cause a significant change in LIMS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3543,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and SEPT5 expression is observed. Does this perturbation lead to a significant difference in SEPT5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and SEPT5 expression is observed. Does this perturbation lead to a significant difference in SEPT5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of SIGLEC6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of SIGLEC6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and HLTF expression is measured. Determine whether HLTF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and HLTF expression is measured. Determine whether HLTF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of ZMYND8 is measured. Determine whether ZMYND8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of ZMYND8 is measured. Determine whether ZMYND8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in KIAA1432 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in KIAA1432 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1543,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and CTD-2267D19.3 expression is observed. Does this perturbation lead to a significant difference in CTD-2267D19.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and CTD-2267D19.3 expression is observed. Does this perturbation lead to a significant difference in CTD-2267D19.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in APOL4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in APOL4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2413,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and MANF expression is observed. Does this perturbation lead to a significant difference in MANF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and MANF expression is observed. Does this perturbation lead to a significant difference in MANF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of NPDC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of NPDC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and C12orf23 expression is quantified. Does this perturbation result in a significant change in C12orf23 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and C12orf23 expression is quantified. Does this perturbation result in a significant change in C12orf23 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of ZFHX3. Does perturbing TTI2 lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of ZFHX3. Does perturbing TTI2 lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3973,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and SEC23IP expression is observed. Does this perturbation lead to a significant difference in SEC23IP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and SEC23IP expression is observed. Does this perturbation lead to a significant difference in SEC23IP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3278,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor TSC22D4 expression. Decide whether this perturbation leads to a significant alteration in TSC22D4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor TSC22D4 expression. Decide whether this perturbation leads to a significant alteration in TSC22D4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4033,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and NTRK1 expression is observed. Does this perturbation lead to a significant difference in NTRK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and NTRK1 expression is observed. Does this perturbation lead to a significant difference in NTRK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of H1FX is measured. Determine whether H1FX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of H1FX is measured. Determine whether H1FX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of SAMM50. Does this perturbation cause a significant change in SAMM50 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of SAMM50. Does this perturbation cause a significant change in SAMM50 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and TAP1 expression is quantified. Does this perturbation result in a significant change in TAP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and TAP1 expression is quantified. Does this perturbation result in a significant change in TAP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of TRIM38 is measured. Determine whether TRIM38 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of TRIM38 is measured. Determine whether TRIM38 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and TGOLN2 expression is measured. Determine whether TGOLN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and TGOLN2 expression is measured. Determine whether TGOLN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of FGF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of FGF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of LBX1. Does this perturbation cause a significant change in LBX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of LBX1. Does this perturbation cause a significant change in LBX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and GOT1 expression is measured. Determine whether GOT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and GOT1 expression is measured. Determine whether GOT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
628,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor SAMM50 expression. Decide whether this perturbation leads to a significant alteration in SAMM50 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor SAMM50 expression. Decide whether this perturbation leads to a significant alteration in SAMM50 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4200,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of IL18R1 is measured. Does this perturbation cause a significant change in IL18R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of IL18R1 is measured. Does this perturbation cause a significant change in IL18R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
888,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor GATA3 expression. Decide whether this perturbation leads to a significant alteration in GATA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor GATA3 expression. Decide whether this perturbation leads to a significant alteration in GATA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and DYNC1H1 expression is measured. Determine whether DYNC1H1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and DYNC1H1 expression is measured. Determine whether DYNC1H1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of VIMP. Does this perturbation cause a significant change in VIMP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of VIMP. Does this perturbation cause a significant change in VIMP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
5134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of CTC-308K20.1. Does this perturbation cause a significant change in CTC-308K20.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of CTC-308K20.1. Does this perturbation cause a significant change in CTC-308K20.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in TLK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in TLK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of SNRNP25. Does perturbing SLC39A7 lead to a significant change in SNRNP25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of SNRNP25. Does perturbing SLC39A7 lead to a significant change in SNRNP25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4518,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor HM13 expression. Decide whether this perturbation leads to a significant alteration in HM13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor HM13 expression. Decide whether this perturbation leads to a significant alteration in HM13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and TOB2 expression is measured. Determine whether TOB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and TOB2 expression is measured. Determine whether TOB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of CPQ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of CPQ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of ARHGAP30. Does perturbing MRGBP lead to a significant change in ARHGAP30 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of ARHGAP30. Does perturbing MRGBP lead to a significant change in ARHGAP30 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4330,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of GRN is measured. Does this perturbation cause a significant change in GRN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of GRN is measured. Does this perturbation cause a significant change in GRN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of RP11-247A12.2. Does perturbing ATP5B lead to a significant change in RP11-247A12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of RP11-247A12.2. Does perturbing ATP5B lead to a significant change in RP11-247A12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and EXOC3L2 expression is measured. Determine whether EXOC3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and EXOC3L2 expression is measured. Determine whether EXOC3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and ANKLE2 expression is quantified. Does this perturbation result in a significant change in ANKLE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and ANKLE2 expression is quantified. Does this perturbation result in a significant change in ANKLE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of CFH is measured. Determine whether CFH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of CFH is measured. Determine whether CFH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in RP11-24F11.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in RP11-24F11.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of SNHG10. Does perturbing CAD lead to a significant change in SNHG10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of SNHG10. Does perturbing CAD lead to a significant change in SNHG10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of NOXA1. Does perturbing SAMM50 lead to a significant change in NOXA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of NOXA1. Does perturbing SAMM50 lead to a significant change in NOXA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and KIAA1731 expression is measured. Determine whether KIAA1731 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and KIAA1731 expression is measured. Determine whether KIAA1731 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and POU2F2 expression is quantified. Does this perturbation result in a significant change in POU2F2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and POU2F2 expression is quantified. Does this perturbation result in a significant change in POU2F2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4408,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor RSAD2 expression. Decide whether this perturbation leads to a significant alteration in RSAD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor RSAD2 expression. Decide whether this perturbation leads to a significant alteration in RSAD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and RP11-247A12.2 expression is measured. Determine whether RP11-247A12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and RP11-247A12.2 expression is measured. Determine whether RP11-247A12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
778,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor JUND expression. Decide whether this perturbation leads to a significant alteration in JUND expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor JUND expression. Decide whether this perturbation leads to a significant alteration in JUND expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PHF19 expression is measured. Determine whether PHF19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PHF19 expression is measured. Determine whether PHF19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of H1FX. Does perturbing EIF2B3 lead to a significant change in H1FX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of H1FX. Does perturbing EIF2B3 lead to a significant change in H1FX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and RP11-471M2.3 expression is quantified. Does this perturbation result in a significant change in RP11-471M2.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and RP11-471M2.3 expression is quantified. Does this perturbation result in a significant change in RP11-471M2.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
393,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and GDF11 expression is observed. Does this perturbation lead to a significant difference in GDF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and GDF11 expression is observed. Does this perturbation lead to a significant difference in GDF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2903,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and VAMP2 expression is observed. Does this perturbation lead to a significant difference in VAMP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and VAMP2 expression is observed. Does this perturbation lead to a significant difference in VAMP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and FGF11 expression is measured. Determine whether FGF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and FGF11 expression is measured. Determine whether FGF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
668,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor PTBP3 expression. Decide whether this perturbation leads to a significant alteration in PTBP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor PTBP3 expression. Decide whether this perturbation leads to a significant alteration in PTBP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of CHST12. Does perturbing KCTD16 lead to a significant change in CHST12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of CHST12. Does perturbing KCTD16 lead to a significant change in CHST12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in SBF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in SBF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1278,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor BAMBI expression. Decide whether this perturbation leads to a significant alteration in BAMBI expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor BAMBI expression. Decide whether this perturbation leads to a significant alteration in BAMBI expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2918,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor AFF1 expression. Decide whether this perturbation leads to a significant alteration in AFF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor AFF1 expression. Decide whether this perturbation leads to a significant alteration in AFF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1023,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and HIST1H1E expression is observed. Does this perturbation lead to a significant difference in HIST1H1E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and HIST1H1E expression is observed. Does this perturbation lead to a significant difference in HIST1H1E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1148,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor SP100 expression. Decide whether this perturbation leads to a significant alteration in SP100 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor SP100 expression. Decide whether this perturbation leads to a significant alteration in SP100 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2328,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor H3F3B expression. Decide whether this perturbation leads to a significant alteration in H3F3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor H3F3B expression. Decide whether this perturbation leads to a significant alteration in H3F3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in ABI2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in ABI2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of DNASE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of DNASE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of KCNQ1OT1 is measured. Determine whether KCNQ1OT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of KCNQ1OT1 is measured. Determine whether KCNQ1OT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and ERV3-1 expression is measured. Determine whether ERV3-1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and ERV3-1 expression is measured. Determine whether ERV3-1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of EPS15. Does perturbing XRN1 lead to a significant change in EPS15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of EPS15. Does perturbing XRN1 lead to a significant change in EPS15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in GOT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in GOT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in C3AR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in C3AR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2043,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
123,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and NRIP1 expression is observed. Does this perturbation lead to a significant difference in NRIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and NRIP1 expression is observed. Does this perturbation lead to a significant difference in NRIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and PBDC1 expression is quantified. Does this perturbation result in a significant change in PBDC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and PBDC1 expression is quantified. Does this perturbation result in a significant change in PBDC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4163,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and SSBP2 expression is observed. Does this perturbation lead to a significant difference in SSBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and SSBP2 expression is observed. Does this perturbation lead to a significant difference in SSBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in NPDC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in NPDC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of KCTD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of KCTD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and NSD1 expression is measured. Determine whether NSD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and NSD1 expression is measured. Determine whether NSD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3550,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of CCRL2 is measured. Does this perturbation cause a significant change in CCRL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of CCRL2 is measured. Does this perturbation cause a significant change in CCRL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1108,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor ZNF280B expression. Decide whether this perturbation leads to a significant alteration in ZNF280B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor ZNF280B expression. Decide whether this perturbation leads to a significant alteration in ZNF280B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of ZC3H7A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of ZC3H7A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1273,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and BAMBI expression is observed. Does this perturbation lead to a significant difference in BAMBI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and BAMBI expression is observed. Does this perturbation lead to a significant difference in BAMBI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and RP11-227G15.8 expression is measured. Determine whether RP11-227G15.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and RP11-227G15.8 expression is measured. Determine whether RP11-227G15.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2830,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of EXO1 is measured. Does this perturbation cause a significant change in EXO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of EXO1 is measured. Does this perturbation cause a significant change in EXO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ARHGAP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ARHGAP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of GS1-166A23.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of GS1-166A23.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
18,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor P4HA2 expression. Decide whether this perturbation leads to a significant alteration in P4HA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor P4HA2 expression. Decide whether this perturbation leads to a significant alteration in P4HA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and C10orf32 expression is quantified. Does this perturbation result in a significant change in C10orf32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and C10orf32 expression is quantified. Does this perturbation result in a significant change in C10orf32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of CTD-2001C12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of CTD-2001C12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of JUND indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of JUND indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of ATXN7L3B is measured. Determine whether ATXN7L3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of ATXN7L3B is measured. Determine whether ATXN7L3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4648,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor S100A11 expression. Decide whether this perturbation leads to a significant alteration in S100A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor S100A11 expression. Decide whether this perturbation leads to a significant alteration in S100A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
24,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of EP300 is measured. Determine whether EP300 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of EP300 is measured. Determine whether EP300 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in CD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in CD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of GPRC5C. Does this perturbation cause a significant change in GPRC5C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of GPRC5C. Does this perturbation cause a significant change in GPRC5C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3038,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor RP11-838N2.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-838N2.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor RP11-838N2.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-838N2.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of PAK1IP1. Does this perturbation cause a significant change in PAK1IP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of PAK1IP1. Does this perturbation cause a significant change in PAK1IP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1388,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor ZEB1 expression. Decide whether this perturbation leads to a significant alteration in ZEB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor ZEB1 expression. Decide whether this perturbation leads to a significant alteration in ZEB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in IL2RB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in IL2RB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and KIAA1432 expression is quantified. Does this perturbation result in a significant change in KIAA1432 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and KIAA1432 expression is quantified. Does this perturbation result in a significant change in KIAA1432 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of RTN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of RTN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and RBM12B-AS1 expression is measured. Determine whether RBM12B-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and RBM12B-AS1 expression is measured. Determine whether RBM12B-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4010,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of DNMBP is measured. Does this perturbation cause a significant change in DNMBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of DNMBP is measured. Does this perturbation cause a significant change in DNMBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and MT2A expression is quantified. Does this perturbation result in a significant change in MT2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and MT2A expression is quantified. Does this perturbation result in a significant change in MT2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
383,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and HIST1H2AM expression is observed. Does this perturbation lead to a significant difference in HIST1H2AM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and HIST1H2AM expression is observed. Does this perturbation lead to a significant difference in HIST1H2AM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of BOLA3 is measured. Determine whether BOLA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of BOLA3 is measured. Determine whether BOLA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2488,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor HLTF expression. Decide whether this perturbation leads to a significant alteration in HLTF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor HLTF expression. Decide whether this perturbation leads to a significant alteration in HLTF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3158,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor SLC25A35 expression. Decide whether this perturbation leads to a significant alteration in SLC25A35 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor SLC25A35 expression. Decide whether this perturbation leads to a significant alteration in SLC25A35 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3860,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of TNFRSF10B is measured. Does this perturbation cause a significant change in TNFRSF10B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of TNFRSF10B is measured. Does this perturbation cause a significant change in TNFRSF10B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in ANXA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in ANXA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3123,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and RGS20 expression is observed. Does this perturbation lead to a significant difference in RGS20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and RGS20 expression is observed. Does this perturbation lead to a significant difference in RGS20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of SPAST. Does perturbing DARS lead to a significant change in SPAST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of SPAST. Does perturbing DARS lead to a significant change in SPAST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1203,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and GMEB1 expression is observed. Does this perturbation lead to a significant difference in GMEB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and GMEB1 expression is observed. Does this perturbation lead to a significant difference in GMEB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of LRRC4B is measured. Determine whether LRRC4B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of LRRC4B is measured. Determine whether LRRC4B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1590,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of LBX1 is measured. Does this perturbation cause a significant change in LBX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of LBX1 is measured. Does this perturbation cause a significant change in LBX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in DOCK8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in DOCK8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1728,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor VIM-AS1 expression. Decide whether this perturbation leads to a significant alteration in VIM-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor VIM-AS1 expression. Decide whether this perturbation leads to a significant alteration in VIM-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of H3F3B is measured. Determine whether H3F3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of H3F3B is measured. Determine whether H3F3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and EGLN3 expression is measured. Determine whether EGLN3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and EGLN3 expression is measured. Determine whether EGLN3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of ZNF789 is measured. Determine whether ZNF789 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of ZNF789 is measured. Determine whether ZNF789 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
46,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of LPAR5 is measured. Determine whether LPAR5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of LPAR5 is measured. Determine whether LPAR5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1403,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and GUSB expression is observed. Does this perturbation lead to a significant difference in GUSB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and GUSB expression is observed. Does this perturbation lead to a significant difference in GUSB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in HIST1H2AC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in HIST1H2AC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of RP11-445H22.3 is measured. Determine whether RP11-445H22.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of RP11-445H22.3 is measured. Determine whether RP11-445H22.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in LBX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in LBX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1378,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor KCTD1 expression. Decide whether this perturbation leads to a significant alteration in KCTD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor KCTD1 expression. Decide whether this perturbation leads to a significant alteration in KCTD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
290,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of ATP11B is measured. Does this perturbation cause a significant change in ATP11B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of ATP11B is measured. Does this perturbation cause a significant change in ATP11B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1383,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and ZEB1 expression is observed. Does this perturbation lead to a significant difference in ZEB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and ZEB1 expression is observed. Does this perturbation lead to a significant difference in ZEB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of WHSC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of WHSC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and RP11-38P22.2 expression is measured. Determine whether RP11-38P22.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and RP11-38P22.2 expression is measured. Determine whether RP11-38P22.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of KANSL1L. Does this perturbation cause a significant change in KANSL1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of KANSL1L. Does this perturbation cause a significant change in KANSL1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and CHD3 expression is measured. Determine whether CHD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and CHD3 expression is measured. Determine whether CHD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of FCGR2A. Does perturbing TTI2 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of FCGR2A. Does perturbing TTI2 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4060,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of CENPF is measured. Does this perturbation cause a significant change in CENPF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of CENPF is measured. Does this perturbation cause a significant change in CENPF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of CST7 is measured. Determine whether CST7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of CST7 is measured. Determine whether CST7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
553,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and OPTN expression is observed. Does this perturbation lead to a significant difference in OPTN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and OPTN expression is observed. Does this perturbation lead to a significant difference in OPTN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of ATAD2B is measured. Determine whether ATAD2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of ATAD2B is measured. Determine whether ATAD2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and ATF6 expression is measured. Determine whether ATF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and ATF6 expression is measured. Determine whether ATF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3468,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor CHST12 expression. Decide whether this perturbation leads to a significant alteration in CHST12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor CHST12 expression. Decide whether this perturbation leads to a significant alteration in CHST12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2228,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor GPRC5C expression. Decide whether this perturbation leads to a significant alteration in GPRC5C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor GPRC5C expression. Decide whether this perturbation leads to a significant alteration in GPRC5C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and PTPRC expression is measured. Determine whether PTPRC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and PTPRC expression is measured. Determine whether PTPRC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of C12orf23. Does this perturbation cause a significant change in C12orf23 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of C12orf23. Does this perturbation cause a significant change in C12orf23 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of ATXN7L3B. Does this perturbation cause a significant change in ATXN7L3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of ATXN7L3B. Does this perturbation cause a significant change in ATXN7L3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of ATF7IP2 is measured. Determine whether ATF7IP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of ATF7IP2 is measured. Determine whether ATF7IP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and VIM-AS1 expression is quantified. Does this perturbation result in a significant change in VIM-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and VIM-AS1 expression is quantified. Does this perturbation result in a significant change in VIM-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of FAM114A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of FAM114A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of GATA3. Does perturbing AMIGO3 lead to a significant change in GATA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of GATA3. Does perturbing AMIGO3 lead to a significant change in GATA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of NOSTRIN. Does perturbing SRPRB lead to a significant change in NOSTRIN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of NOSTRIN. Does perturbing SRPRB lead to a significant change in NOSTRIN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1330,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of RCBTB2 is measured. Does this perturbation cause a significant change in RCBTB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of RCBTB2 is measured. Does this perturbation cause a significant change in RCBTB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3983,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and PELO expression is observed. Does this perturbation lead to a significant difference in PELO expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and PELO expression is observed. Does this perturbation lead to a significant difference in PELO expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in MORC2-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in MORC2-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of NRIP1. Does this perturbation cause a significant change in NRIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of NRIP1. Does this perturbation cause a significant change in NRIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of NINJ2. Does this perturbation cause a significant change in NINJ2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of NINJ2. Does this perturbation cause a significant change in NINJ2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2280,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of TNFRSF10B is measured. Does this perturbation cause a significant change in TNFRSF10B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of TNFRSF10B is measured. Does this perturbation cause a significant change in TNFRSF10B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of DST. Does this perturbation cause a significant change in DST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of DST. Does this perturbation cause a significant change in DST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of MANF is measured. Determine whether MANF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of MANF is measured. Determine whether MANF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
563,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and IL32 expression is observed. Does this perturbation lead to a significant difference in IL32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and IL32 expression is observed. Does this perturbation lead to a significant difference in IL32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of BACH2. Does this perturbation cause a significant change in BACH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of BACH2. Does this perturbation cause a significant change in BACH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3548,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor SEPT5 expression. Decide whether this perturbation leads to a significant alteration in SEPT5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor SEPT5 expression. Decide whether this perturbation leads to a significant alteration in SEPT5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and HIST1H3D expression is quantified. Does this perturbation result in a significant change in HIST1H3D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and HIST1H3D expression is quantified. Does this perturbation result in a significant change in HIST1H3D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4728,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor RP11-322J23.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-322J23.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor RP11-322J23.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-322J23.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
81,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of PHF3. Does perturbing ZNF326 lead to a significant change in PHF3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of PHF3. Does perturbing ZNF326 lead to a significant change in PHF3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of RP11-247A12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of RP11-247A12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of SERPINF2 is measured. Determine whether SERPINF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of SERPINF2 is measured. Determine whether SERPINF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of NFAT5 is measured. Determine whether NFAT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of NFAT5 is measured. Determine whether NFAT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
533,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and IRF7 expression is observed. Does this perturbation lead to a significant difference in IRF7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and IRF7 expression is observed. Does this perturbation lead to a significant difference in IRF7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of NRIP1 is measured. Determine whether NRIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of NRIP1 is measured. Determine whether NRIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
883,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and GATA3 expression is observed. Does this perturbation lead to a significant difference in GATA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and GATA3 expression is observed. Does this perturbation lead to a significant difference in GATA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1760,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of C12orf23 is measured. Does this perturbation cause a significant change in C12orf23 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of C12orf23 is measured. Does this perturbation cause a significant change in C12orf23 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of TLK2 is measured. Determine whether TLK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of TLK2 is measured. Determine whether TLK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2210,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of ACSM3 is measured. Does this perturbation cause a significant change in ACSM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of ACSM3 is measured. Does this perturbation cause a significant change in ACSM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of FAM114A1. Does perturbing SLMO2 lead to a significant change in FAM114A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of FAM114A1. Does perturbing SLMO2 lead to a significant change in FAM114A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of KDM1B. Does perturbing UFL1 lead to a significant change in KDM1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of KDM1B. Does perturbing UFL1 lead to a significant change in KDM1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of PRRC2B is measured. Determine whether PRRC2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of PRRC2B is measured. Determine whether PRRC2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and TKTL1 expression is quantified. Does this perturbation result in a significant change in TKTL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and TKTL1 expression is quantified. Does this perturbation result in a significant change in TKTL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in RP11-573D15.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in RP11-573D15.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2358,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor IL13RA1 expression. Decide whether this perturbation leads to a significant alteration in IL13RA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor IL13RA1 expression. Decide whether this perturbation leads to a significant alteration in IL13RA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of IFNGR1. Does perturbing MANF lead to a significant change in IFNGR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of IFNGR1. Does perturbing MANF lead to a significant change in IFNGR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2933,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and RP11-227G15.8 expression is observed. Does this perturbation lead to a significant difference in RP11-227G15.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and RP11-227G15.8 expression is observed. Does this perturbation lead to a significant difference in RP11-227G15.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and REST expression is measured. Determine whether REST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and REST expression is measured. Determine whether REST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in RNF19A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in RNF19A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of LAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of LAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of CTD-2267D19.3. Does this perturbation cause a significant change in CTD-2267D19.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of CTD-2267D19.3. Does this perturbation cause a significant change in CTD-2267D19.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in NINJ2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in NINJ2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and QSER1 expression is quantified. Does this perturbation result in a significant change in QSER1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and QSER1 expression is quantified. Does this perturbation result in a significant change in QSER1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of ZNF292 is measured. Determine whether ZNF292 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of ZNF292 is measured. Determine whether ZNF292 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1838,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor ATP2A3 expression. Decide whether this perturbation leads to a significant alteration in ATP2A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor ATP2A3 expression. Decide whether this perturbation leads to a significant alteration in ATP2A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and CENPC expression is quantified. Does this perturbation result in a significant change in CENPC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and CENPC expression is quantified. Does this perturbation result in a significant change in CENPC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3028,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor HIST1H2AC expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor HIST1H2AC expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of PPP1R16B. Does this perturbation cause a significant change in PPP1R16B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of PPP1R16B. Does this perturbation cause a significant change in PPP1R16B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and LAMP2 expression is measured. Determine whether LAMP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and LAMP2 expression is measured. Determine whether LAMP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
77,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of CEBPG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of CEBPG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of CPQ is measured. Determine whether CPQ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of CPQ is measured. Determine whether CPQ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and TRPM4 expression is measured. Determine whether TRPM4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and TRPM4 expression is measured. Determine whether TRPM4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of TAGLN. Does perturbing STT3A lead to a significant change in TAGLN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of TAGLN. Does perturbing STT3A lead to a significant change in TAGLN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in TACC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in TACC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of BAMBI is measured. Determine whether BAMBI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of BAMBI is measured. Determine whether BAMBI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of NXF1 is measured. Determine whether NXF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of NXF1 is measured. Determine whether NXF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of RP11-789C1.1. Does perturbing DARS lead to a significant change in RP11-789C1.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of RP11-789C1.1. Does perturbing DARS lead to a significant change in RP11-789C1.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4110,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of CDCA3 is measured. Does this perturbation cause a significant change in CDCA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of CDCA3 is measured. Does this perturbation cause a significant change in CDCA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of QSER1 is measured. Determine whether QSER1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of QSER1 is measured. Determine whether QSER1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3308,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor SMIM14 expression. Decide whether this perturbation leads to a significant alteration in SMIM14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor SMIM14 expression. Decide whether this perturbation leads to a significant alteration in SMIM14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and CTC-308K20.1 expression is quantified. Does this perturbation result in a significant change in CTC-308K20.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and CTC-308K20.1 expression is quantified. Does this perturbation result in a significant change in CTC-308K20.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of GALNT7. Does this perturbation cause a significant change in GALNT7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of GALNT7. Does this perturbation cause a significant change in GALNT7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in LTN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in LTN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and ZNF292 expression is measured. Determine whether ZNF292 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and ZNF292 expression is measured. Determine whether ZNF292 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of C9orf64. Does this perturbation cause a significant change in C9orf64 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of C9orf64. Does this perturbation cause a significant change in C9orf64 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4363,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and USP34 expression is observed. Does this perturbation lead to a significant difference in USP34 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and USP34 expression is observed. Does this perturbation lead to a significant difference in USP34 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2773,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and LAMP2 expression is observed. Does this perturbation lead to a significant difference in LAMP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and LAMP2 expression is observed. Does this perturbation lead to a significant difference in LAMP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in DSC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in DSC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and EPS15 expression is measured. Determine whether EPS15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and EPS15 expression is measured. Determine whether EPS15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
93,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RP11-141B14.1 expression is observed. Does this perturbation lead to a significant difference in RP11-141B14.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RP11-141B14.1 expression is observed. Does this perturbation lead to a significant difference in RP11-141B14.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3623,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and NRIP1 expression is observed. Does this perturbation lead to a significant difference in NRIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and NRIP1 expression is observed. Does this perturbation lead to a significant difference in NRIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of ITGB2. Does this perturbation cause a significant change in ITGB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of ITGB2. Does this perturbation cause a significant change in ITGB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3783,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and LTN1 expression is observed. Does this perturbation lead to a significant difference in LTN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and LTN1 expression is observed. Does this perturbation lead to a significant difference in LTN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1933,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and GUSB expression is observed. Does this perturbation lead to a significant difference in GUSB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and GUSB expression is observed. Does this perturbation lead to a significant difference in GUSB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of RNF8. Does perturbing TTI1 lead to a significant change in RNF8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of RNF8. Does perturbing TTI1 lead to a significant change in RNF8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4598,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor LINC00862 expression. Decide whether this perturbation leads to a significant alteration in LINC00862 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor LINC00862 expression. Decide whether this perturbation leads to a significant alteration in LINC00862 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3683,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and SLC27A2 expression is observed. Does this perturbation lead to a significant difference in SLC27A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and SLC27A2 expression is observed. Does this perturbation lead to a significant difference in SLC27A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and RP13-216E22.4 expression is measured. Determine whether RP13-216E22.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and RP13-216E22.4 expression is measured. Determine whether RP13-216E22.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3673,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and ZC3H7A expression is observed. Does this perturbation lead to a significant difference in ZC3H7A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and ZC3H7A expression is observed. Does this perturbation lead to a significant difference in ZC3H7A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RGS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RGS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and HIST1H1E expression is measured. Determine whether HIST1H1E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and HIST1H1E expression is measured. Determine whether HIST1H1E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in HOTAIRM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in HOTAIRM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
758,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor TSNAXIP1 expression. Decide whether this perturbation leads to a significant alteration in TSNAXIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor TSNAXIP1 expression. Decide whether this perturbation leads to a significant alteration in TSNAXIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of DOCK11. Does perturbing EIF2B4 lead to a significant change in DOCK11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of DOCK11. Does perturbing EIF2B4 lead to a significant change in DOCK11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and FGF11 expression is quantified. Does this perturbation result in a significant change in FGF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and FGF11 expression is quantified. Does this perturbation result in a significant change in FGF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in PPP4R2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in PPP4R2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of RP11-90P5.2. Does this perturbation cause a significant change in RP11-90P5.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of RP11-90P5.2. Does this perturbation cause a significant change in RP11-90P5.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4983,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and UHMK1 expression is observed. Does this perturbation lead to a significant difference in UHMK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and UHMK1 expression is observed. Does this perturbation lead to a significant difference in UHMK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1558,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor RP11-381O7.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-381O7.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor RP11-381O7.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-381O7.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of RP11-247A12.2 is measured. Determine whether RP11-247A12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of RP11-247A12.2 is measured. Determine whether RP11-247A12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3510,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of TMEM60 is measured. Does this perturbation cause a significant change in TMEM60 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of TMEM60 is measured. Does this perturbation cause a significant change in TMEM60 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
5042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and LAMP2 expression is quantified. Does this perturbation result in a significant change in LAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and LAMP2 expression is quantified. Does this perturbation result in a significant change in LAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and KDM1B expression is quantified. Does this perturbation result in a significant change in KDM1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and KDM1B expression is quantified. Does this perturbation result in a significant change in KDM1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and KLF3 expression is measured. Determine whether KLF3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and KLF3 expression is measured. Determine whether KLF3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of TFPI. Does perturbing SLC35B1 lead to a significant change in TFPI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of TFPI. Does perturbing SLC35B1 lead to a significant change in TFPI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1350,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of TAGLN is measured. Does this perturbation cause a significant change in TAGLN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of TAGLN is measured. Does this perturbation cause a significant change in TAGLN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of RP11-61E11.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of RP11-61E11.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of ANKRD10. Does perturbing SRPRB lead to a significant change in ANKRD10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of ANKRD10. Does perturbing SRPRB lead to a significant change in ANKRD10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and PARP11 expression is measured. Determine whether PARP11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and PARP11 expression is measured. Determine whether PARP11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2583,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and KIF4A expression is observed. Does this perturbation lead to a significant difference in KIF4A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and KIF4A expression is observed. Does this perturbation lead to a significant difference in KIF4A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of ATP11B. Does this perturbation cause a significant change in ATP11B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of ATP11B. Does this perturbation cause a significant change in ATP11B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2600,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of CTCFL is measured. Does this perturbation cause a significant change in CTCFL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of CTCFL is measured. Does this perturbation cause a significant change in CTCFL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
400,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of RP11-90P5.2 is measured. Does this perturbation cause a significant change in RP11-90P5.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of RP11-90P5.2 is measured. Does this perturbation cause a significant change in RP11-90P5.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of ANKLE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of ANKLE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of KIF4A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of KIF4A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in OXLD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in OXLD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and IFNGR1 expression is quantified. Does this perturbation result in a significant change in IFNGR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and IFNGR1 expression is quantified. Does this perturbation result in a significant change in IFNGR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of LTB. Does this perturbation cause a significant change in LTB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of LTB. Does this perturbation cause a significant change in LTB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of WDR3 is measured. Determine whether WDR3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of WDR3 is measured. Determine whether WDR3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
88,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor PHF3 expression. Decide whether this perturbation leads to a significant alteration in PHF3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor PHF3 expression. Decide whether this perturbation leads to a significant alteration in PHF3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2728,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of ZEB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of ZEB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3808,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor TOPBP1 expression. Decide whether this perturbation leads to a significant alteration in TOPBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor TOPBP1 expression. Decide whether this perturbation leads to a significant alteration in TOPBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of RTN2 is measured. Determine whether RTN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of RTN2 is measured. Determine whether RTN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of PTPN11. Does perturbing IER3IP1 lead to a significant change in PTPN11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of PTPN11. Does perturbing IER3IP1 lead to a significant change in PTPN11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and VIMP expression is measured. Determine whether VIMP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and VIMP expression is measured. Determine whether VIMP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of NUFIP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of NUFIP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of APOL4. Does this perturbation cause a significant change in APOL4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of APOL4. Does this perturbation cause a significant change in APOL4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of CD58. Does perturbing GBF1 lead to a significant change in CD58 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of CD58. Does perturbing GBF1 lead to a significant change in CD58 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and POU2F2 expression is measured. Determine whether POU2F2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and POU2F2 expression is measured. Determine whether POU2F2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of TUBA1C. Does this perturbation cause a significant change in TUBA1C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of TUBA1C. Does this perturbation cause a significant change in TUBA1C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of TAP1. Does this perturbation cause a significant change in TAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of TAP1. Does this perturbation cause a significant change in TAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of C3AR1. Does this perturbation cause a significant change in C3AR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of C3AR1. Does this perturbation cause a significant change in C3AR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and IL8 expression is measured. Determine whether IL8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and IL8 expression is measured. Determine whether IL8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and LTB expression is quantified. Does this perturbation result in a significant change in LTB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and LTB expression is quantified. Does this perturbation result in a significant change in LTB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of PPP4R2. Does this perturbation cause a significant change in PPP4R2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of PPP4R2. Does this perturbation cause a significant change in PPP4R2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of ANXA4 is measured. Determine whether ANXA4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of ANXA4 is measured. Determine whether ANXA4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and ZC3H7A expression is measured. Determine whether ZC3H7A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and ZC3H7A expression is measured. Determine whether ZC3H7A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of EP300. Does perturbing SYVN1 lead to a significant change in EP300 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of EP300. Does perturbing SYVN1 lead to a significant change in EP300 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4488,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor PPP1R16B expression. Decide whether this perturbation leads to a significant alteration in PPP1R16B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor PPP1R16B expression. Decide whether this perturbation leads to a significant alteration in PPP1R16B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in GS1-166A23.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in GS1-166A23.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of WDR72 is measured. Determine whether WDR72 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of WDR72 is measured. Determine whether WDR72 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1310,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of SNHG10 is measured. Does this perturbation cause a significant change in SNHG10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of SNHG10 is measured. Does this perturbation cause a significant change in SNHG10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and HIST1H2AC expression is measured. Determine whether HIST1H2AC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and HIST1H2AC expression is measured. Determine whether HIST1H2AC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4443,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and CTBS expression is observed. Does this perturbation lead to a significant difference in CTBS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and CTBS expression is observed. Does this perturbation lead to a significant difference in CTBS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
408,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor RP11-90P5.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-90P5.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor RP11-90P5.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-90P5.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and SIGLEC6 expression is quantified. Does this perturbation result in a significant change in SIGLEC6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and SIGLEC6 expression is quantified. Does this perturbation result in a significant change in SIGLEC6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and FYTTD1 expression is quantified. Does this perturbation result in a significant change in FYTTD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and FYTTD1 expression is quantified. Does this perturbation result in a significant change in FYTTD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
268,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor DOK3 expression. Decide whether this perturbation leads to a significant alteration in DOK3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor DOK3 expression. Decide whether this perturbation leads to a significant alteration in DOK3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and RP11-499F3.2 expression is measured. Determine whether RP11-499F3.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and RP11-499F3.2 expression is measured. Determine whether RP11-499F3.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of ATP6V1B2 is measured. Determine whether ATP6V1B2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of ATP6V1B2 is measured. Determine whether ATP6V1B2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of ESCO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of ESCO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in ZCCHC11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in ZCCHC11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of OPTN. Does perturbing YIPF5 lead to a significant change in OPTN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of OPTN. Does perturbing YIPF5 lead to a significant change in OPTN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1300,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of ITGB2 is measured. Does this perturbation cause a significant change in ITGB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of ITGB2 is measured. Does this perturbation cause a significant change in ITGB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and PTGS1 expression is measured. Determine whether PTGS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and PTGS1 expression is measured. Determine whether PTGS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of HERC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of HERC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of ARHGDIB. Does perturbing TMEM167A lead to a significant change in ARHGDIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of ARHGDIB. Does perturbing TMEM167A lead to a significant change in ARHGDIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
720,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of RP11-132A1.4 is measured. Does this perturbation cause a significant change in RP11-132A1.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of RP11-132A1.4 is measured. Does this perturbation cause a significant change in RP11-132A1.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in TLK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in TLK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of RIMS3. Does this perturbation cause a significant change in RIMS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of RIMS3. Does this perturbation cause a significant change in RIMS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of C3AR1 is measured. Determine whether C3AR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of C3AR1 is measured. Determine whether C3AR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in ARHGDIB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in ARHGDIB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2668,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor ASPM expression. Decide whether this perturbation leads to a significant alteration in ASPM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor ASPM expression. Decide whether this perturbation leads to a significant alteration in ASPM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in IL18R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in IL18R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of DDX3X. Does this perturbation cause a significant change in DDX3X expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of DDX3X. Does this perturbation cause a significant change in DDX3X expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3650,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of KCNJ13 is measured. Does this perturbation cause a significant change in KCNJ13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of KCNJ13 is measured. Does this perturbation cause a significant change in KCNJ13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4818,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor MBNL1 expression. Decide whether this perturbation leads to a significant alteration in MBNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor MBNL1 expression. Decide whether this perturbation leads to a significant alteration in MBNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and HAGH expression is measured. Determine whether HAGH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and HAGH expression is measured. Determine whether HAGH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
228,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor CASP8 expression. Decide whether this perturbation leads to a significant alteration in CASP8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor CASP8 expression. Decide whether this perturbation leads to a significant alteration in CASP8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2008,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor C1GALT1 expression. Decide whether this perturbation leads to a significant alteration in C1GALT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor C1GALT1 expression. Decide whether this perturbation leads to a significant alteration in C1GALT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of SETX. Does this perturbation cause a significant change in SETX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of SETX. Does this perturbation cause a significant change in SETX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of SLC27A2 is measured. Determine whether SLC27A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of SLC27A2 is measured. Determine whether SLC27A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of ZC3H7A. Does perturbing TIMM44 lead to a significant change in ZC3H7A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of ZC3H7A. Does perturbing TIMM44 lead to a significant change in ZC3H7A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of RP11-573D15.2 is measured. Determine whether RP11-573D15.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of RP11-573D15.2 is measured. Determine whether RP11-573D15.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in NSD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in NSD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of NXF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of NXF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and CDK13 expression is quantified. Does this perturbation result in a significant change in CDK13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and CDK13 expression is quantified. Does this perturbation result in a significant change in CDK13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3070,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PIF1 is measured. Does this perturbation cause a significant change in PIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PIF1 is measured. Does this perturbation cause a significant change in PIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of MYH7B. Does perturbing YIPF5 lead to a significant change in MYH7B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of MYH7B. Does perturbing YIPF5 lead to a significant change in MYH7B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of SPCS2. Does this perturbation cause a significant change in SPCS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of SPCS2. Does this perturbation cause a significant change in SPCS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2170,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of LRRC4B is measured. Does this perturbation cause a significant change in LRRC4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of LRRC4B is measured. Does this perturbation cause a significant change in LRRC4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of TIPARP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of TIPARP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and TET1 expression is measured. Determine whether TET1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and TET1 expression is measured. Determine whether TET1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of NAV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of NAV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of AC015987.1. Does this perturbation cause a significant change in AC015987.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of AC015987.1. Does this perturbation cause a significant change in AC015987.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
790,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of REST is measured. Does this perturbation cause a significant change in REST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of REST is measured. Does this perturbation cause a significant change in REST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of TLN1. Does perturbing IARS2 lead to a significant change in TLN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of TLN1. Does perturbing IARS2 lead to a significant change in TLN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of TOPBP1. Does perturbing TARS lead to a significant change in TOPBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of TOPBP1. Does perturbing TARS lead to a significant change in TOPBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4198,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor CTD-2020K17.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2020K17.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor CTD-2020K17.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2020K17.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
5140,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of RAD51AP1 is measured. Does this perturbation cause a significant change in RAD51AP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of RAD51AP1 is measured. Does this perturbation cause a significant change in RAD51AP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of RP11-666A20.4. Does this perturbation cause a significant change in RP11-666A20.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of RP11-666A20.4. Does this perturbation cause a significant change in RP11-666A20.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of MLEC is measured. Determine whether MLEC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of MLEC is measured. Determine whether MLEC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4703,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and LTB expression is observed. Does this perturbation lead to a significant difference in LTB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and LTB expression is observed. Does this perturbation lead to a significant difference in LTB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of DYNC1H1. Does perturbing ARHGAP22 lead to a significant change in DYNC1H1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of DYNC1H1. Does perturbing ARHGAP22 lead to a significant change in DYNC1H1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3720,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of ARHGAP11A is measured. Does this perturbation cause a significant change in ARHGAP11A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of ARHGAP11A is measured. Does this perturbation cause a significant change in ARHGAP11A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4860,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of NAV2 is measured. Does this perturbation cause a significant change in NAV2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of NAV2 is measured. Does this perturbation cause a significant change in NAV2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2560,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of SBF2 is measured. Does this perturbation cause a significant change in SBF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of SBF2 is measured. Does this perturbation cause a significant change in SBF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of NPAT. Does perturbing PSMD4 lead to a significant change in NPAT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of NPAT. Does perturbing PSMD4 lead to a significant change in NPAT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3258,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor S100A11 expression. Decide whether this perturbation leads to a significant alteration in S100A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor S100A11 expression. Decide whether this perturbation leads to a significant alteration in S100A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of EP300. Does this perturbation cause a significant change in EP300 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of EP300. Does this perturbation cause a significant change in EP300 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1128,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor RP11-640M9.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-640M9.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor RP11-640M9.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-640M9.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3190,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of TRIM24 is measured. Does this perturbation cause a significant change in TRIM24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of TRIM24 is measured. Does this perturbation cause a significant change in TRIM24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2423,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and HIST1H2AM expression is observed. Does this perturbation lead to a significant difference in HIST1H2AM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and HIST1H2AM expression is observed. Does this perturbation lead to a significant difference in HIST1H2AM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and KCNE3 expression is measured. Determine whether KCNE3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and KCNE3 expression is measured. Determine whether KCNE3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3060,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PHF19 is measured. Does this perturbation cause a significant change in PHF19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PHF19 is measured. Does this perturbation cause a significant change in PHF19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and HIST1H2AC expression is quantified. Does this perturbation result in a significant change in HIST1H2AC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and HIST1H2AC expression is quantified. Does this perturbation result in a significant change in HIST1H2AC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of RP11-445H22.3. Does perturbing HYOU1 lead to a significant change in RP11-445H22.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of RP11-445H22.3. Does perturbing HYOU1 lead to a significant change in RP11-445H22.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of RP1-274L7.1. Does this perturbation cause a significant change in RP1-274L7.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of RP1-274L7.1. Does this perturbation cause a significant change in RP1-274L7.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1948,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor GLG1 expression. Decide whether this perturbation leads to a significant alteration in GLG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor GLG1 expression. Decide whether this perturbation leads to a significant alteration in GLG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2510,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of RBM12B-AS1 is measured. Does this perturbation cause a significant change in RBM12B-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of RBM12B-AS1 is measured. Does this perturbation cause a significant change in RBM12B-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4278,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor IDS expression. Decide whether this perturbation leads to a significant alteration in IDS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor IDS expression. Decide whether this perturbation leads to a significant alteration in IDS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
640,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of KANSL1L is measured. Does this perturbation cause a significant change in KANSL1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of KANSL1L is measured. Does this perturbation cause a significant change in KANSL1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of NRIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of NRIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of GCKR. Does perturbing AARS lead to a significant change in GCKR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of GCKR. Does perturbing AARS lead to a significant change in GCKR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and ZNF429 expression is observed. Does this perturbation lead to a significant difference in ZNF429 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and ZNF429 expression is observed. Does this perturbation lead to a significant difference in ZNF429 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and SPAST expression is measured. Determine whether SPAST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and SPAST expression is measured. Determine whether SPAST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and RP11-24F11.2 expression is measured. Determine whether RP11-24F11.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and RP11-24F11.2 expression is measured. Determine whether RP11-24F11.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of TSPAN33 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of TSPAN33 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4868,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor NAV2 expression. Decide whether this perturbation leads to a significant alteration in NAV2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor NAV2 expression. Decide whether this perturbation leads to a significant alteration in NAV2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1703,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and UBE2V1 expression is observed. Does this perturbation lead to a significant difference in UBE2V1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and UBE2V1 expression is observed. Does this perturbation lead to a significant difference in UBE2V1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of GATA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of GATA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of NFE2L3. Does perturbing PDIA6 lead to a significant change in NFE2L3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of NFE2L3. Does perturbing PDIA6 lead to a significant change in NFE2L3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of NFE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of NFE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4098,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor DSC2 expression. Decide whether this perturbation leads to a significant alteration in DSC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor DSC2 expression. Decide whether this perturbation leads to a significant alteration in DSC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of RP3-465N24.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of RP3-465N24.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in RP11-181G12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in RP11-181G12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of RP11-81A22.5 is measured. Determine whether RP11-81A22.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of RP11-81A22.5 is measured. Determine whether RP11-81A22.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in GATA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in GATA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of ZNF429. Does this perturbation cause a significant change in ZNF429 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of ZNF429. Does this perturbation cause a significant change in ZNF429 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in RP11-390B4.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in RP11-390B4.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1533,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and C12orf44 expression is observed. Does this perturbation lead to a significant difference in C12orf44 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and C12orf44 expression is observed. Does this perturbation lead to a significant difference in C12orf44 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and ADAMTS10 expression is quantified. Does this perturbation result in a significant change in ADAMTS10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and ADAMTS10 expression is quantified. Does this perturbation result in a significant change in ADAMTS10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ZFP36L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ZFP36L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of JUND is measured. Determine whether JUND shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of JUND is measured. Determine whether JUND shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RUNX1. Does perturbing MARS lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RUNX1. Does perturbing MARS lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in NFAT5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in NFAT5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1338,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor RCBTB2 expression. Decide whether this perturbation leads to a significant alteration in RCBTB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor RCBTB2 expression. Decide whether this perturbation leads to a significant alteration in RCBTB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of BAMBI. Does perturbing UFL1 lead to a significant change in BAMBI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of BAMBI. Does perturbing UFL1 lead to a significant change in BAMBI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of KLF3 is measured. Determine whether KLF3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of KLF3 is measured. Determine whether KLF3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ARHGAP6 expression is measured. Determine whether ARHGAP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ARHGAP6 expression is measured. Determine whether ARHGAP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1363,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and ZNF678 expression is observed. Does this perturbation lead to a significant difference in ZNF678 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and ZNF678 expression is observed. Does this perturbation lead to a significant difference in ZNF678 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in RSAD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in RSAD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and GDF11 expression is quantified. Does this perturbation result in a significant change in GDF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and GDF11 expression is quantified. Does this perturbation result in a significant change in GDF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of GSN. Does perturbing TTI1 lead to a significant change in GSN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of GSN. Does perturbing TTI1 lead to a significant change in GSN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PHF19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PHF19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3958,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor SERPINF2 expression. Decide whether this perturbation leads to a significant alteration in SERPINF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor SERPINF2 expression. Decide whether this perturbation leads to a significant alteration in SERPINF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of RP11-119J18.1. Does perturbing MRPL39 lead to a significant change in RP11-119J18.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of RP11-119J18.1. Does perturbing MRPL39 lead to a significant change in RP11-119J18.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4568,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor WDR3 expression. Decide whether this perturbation leads to a significant alteration in WDR3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor WDR3 expression. Decide whether this perturbation leads to a significant alteration in WDR3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of UFD1L is measured. Determine whether UFD1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of UFD1L is measured. Determine whether UFD1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of PAXBP1. Does this perturbation cause a significant change in PAXBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of PAXBP1. Does this perturbation cause a significant change in PAXBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and GATA3 expression is measured. Determine whether GATA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and GATA3 expression is measured. Determine whether GATA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and RP11-573D15.2 expression is quantified. Does this perturbation result in a significant change in RP11-573D15.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and RP11-573D15.2 expression is quantified. Does this perturbation result in a significant change in RP11-573D15.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RP11-65L19.4. Does perturbing ZNF326 lead to a significant change in RP11-65L19.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RP11-65L19.4. Does perturbing ZNF326 lead to a significant change in RP11-65L19.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of RP11-360L9.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of RP11-360L9.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of NFE2L3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of NFE2L3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in SLBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in SLBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in ZEB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in ZEB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of BAMBI is measured. Determine whether BAMBI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of BAMBI is measured. Determine whether BAMBI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in CDRT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in CDRT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2780,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3358,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor EXOC3L2 expression. Decide whether this perturbation leads to a significant alteration in EXOC3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor EXOC3L2 expression. Decide whether this perturbation leads to a significant alteration in EXOC3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of MORF4L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of MORF4L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3293,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and GS1-166A23.1 expression is observed. Does this perturbation lead to a significant difference in GS1-166A23.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and GS1-166A23.1 expression is observed. Does this perturbation lead to a significant difference in GS1-166A23.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of KCNQ1OT1. Does this perturbation cause a significant change in KCNQ1OT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of KCNQ1OT1. Does this perturbation cause a significant change in KCNQ1OT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1970,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of CRNDE is measured. Does this perturbation cause a significant change in CRNDE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of CRNDE is measured. Does this perturbation cause a significant change in CRNDE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4328,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor NOSTRIN expression. Decide whether this perturbation leads to a significant alteration in NOSTRIN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor NOSTRIN expression. Decide whether this perturbation leads to a significant alteration in NOSTRIN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RP11-685N10.1. Does this perturbation cause a significant change in RP11-685N10.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RP11-685N10.1. Does this perturbation cause a significant change in RP11-685N10.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and NAV1 expression is measured. Determine whether NAV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and NAV1 expression is measured. Determine whether NAV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
163,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and RIMS3 expression is observed. Does this perturbation lead to a significant difference in RIMS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and RIMS3 expression is observed. Does this perturbation lead to a significant difference in RIMS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and RIMS3 expression is measured. Determine whether RIMS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and RIMS3 expression is measured. Determine whether RIMS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and CCDC69 expression is measured. Determine whether CCDC69 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and CCDC69 expression is measured. Determine whether CCDC69 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in ARHGAP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in ARHGAP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2240,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of AMOTL1 is measured. Does this perturbation cause a significant change in AMOTL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of AMOTL1 is measured. Does this perturbation cause a significant change in AMOTL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4733,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and MTPN expression is observed. Does this perturbation lead to a significant difference in MTPN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and MTPN expression is observed. Does this perturbation lead to a significant difference in MTPN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of AC005540.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of AC005540.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of CTNNB1 is measured. Determine whether CTNNB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of CTNNB1 is measured. Determine whether CTNNB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1580,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of NFE2L3 is measured. Does this perturbation cause a significant change in NFE2L3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of NFE2L3 is measured. Does this perturbation cause a significant change in NFE2L3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4788,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor PDE3B expression. Decide whether this perturbation leads to a significant alteration in PDE3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor PDE3B expression. Decide whether this perturbation leads to a significant alteration in PDE3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of BOLA3. Does this perturbation cause a significant change in BOLA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of BOLA3. Does this perturbation cause a significant change in BOLA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of TAP1. Does perturbing SEC61G lead to a significant change in TAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of TAP1. Does perturbing SEC61G lead to a significant change in TAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and PDE4D expression is measured. Determine whether PDE4D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and PDE4D expression is measured. Determine whether PDE4D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
113,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RP11-65L19.4 expression is observed. Does this perturbation lead to a significant difference in RP11-65L19.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RP11-65L19.4 expression is observed. Does this perturbation lead to a significant difference in RP11-65L19.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of RP11-863K10.7 is measured. Determine whether RP11-863K10.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of RP11-863K10.7 is measured. Determine whether RP11-863K10.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4513,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and HM13 expression is observed. Does this perturbation lead to a significant difference in HM13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and HM13 expression is observed. Does this perturbation lead to a significant difference in HM13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in TAGLN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in TAGLN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2163,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and PDK2 expression is observed. Does this perturbation lead to a significant difference in PDK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and PDK2 expression is observed. Does this perturbation lead to a significant difference in PDK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4603,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and STARD9 expression is observed. Does this perturbation lead to a significant difference in STARD9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and STARD9 expression is observed. Does this perturbation lead to a significant difference in STARD9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and HIST1H2AM expression is quantified. Does this perturbation result in a significant change in HIST1H2AM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and HIST1H2AM expression is quantified. Does this perturbation result in a significant change in HIST1H2AM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2538,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and UQCRB expression is measured. Determine whether UQCRB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and UQCRB expression is measured. Determine whether UQCRB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1433,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and MARCH8 expression is observed. Does this perturbation lead to a significant difference in MARCH8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and MARCH8 expression is observed. Does this perturbation lead to a significant difference in MARCH8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of ADAMTS10. Does this perturbation cause a significant change in ADAMTS10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of ADAMTS10. Does this perturbation cause a significant change in ADAMTS10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of DKFZP779L1853. Does this perturbation cause a significant change in DKFZP779L1853 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of DKFZP779L1853. Does this perturbation cause a significant change in DKFZP779L1853 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of SBF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of SBF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in RBM12B-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in RBM12B-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of EP300. Does this perturbation cause a significant change in EP300 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of EP300. Does this perturbation cause a significant change in EP300 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4133,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and WDR72 expression is observed. Does this perturbation lead to a significant difference in WDR72 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and WDR72 expression is observed. Does this perturbation lead to a significant difference in WDR72 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3540,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of SEPT5 is measured. Does this perturbation cause a significant change in SEPT5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of SEPT5 is measured. Does this perturbation cause a significant change in SEPT5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of HIST1H3D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of HIST1H3D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of PRRC2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of PRRC2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and PPP1R16B expression is quantified. Does this perturbation result in a significant change in PPP1R16B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and PPP1R16B expression is quantified. Does this perturbation result in a significant change in PPP1R16B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
5034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of CELF6. Does this perturbation cause a significant change in CELF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of CELF6. Does this perturbation cause a significant change in CELF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of EXO1. Does this perturbation cause a significant change in EXO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of EXO1. Does this perturbation cause a significant change in EXO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of USP34 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of USP34 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
41,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of LPAR5. Does perturbing CREB1 lead to a significant change in LPAR5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of LPAR5. Does perturbing CREB1 lead to a significant change in LPAR5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and STC2 expression is measured. Determine whether STC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and STC2 expression is measured. Determine whether STC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and GS1-166A23.1 expression is quantified. Does this perturbation result in a significant change in GS1-166A23.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and GS1-166A23.1 expression is quantified. Does this perturbation result in a significant change in GS1-166A23.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of OPTN. Does this perturbation cause a significant change in OPTN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of OPTN. Does this perturbation cause a significant change in OPTN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
388,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor HIST1H2AM expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor HIST1H2AM expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and PAK1IP1 expression is quantified. Does this perturbation result in a significant change in PAK1IP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and PAK1IP1 expression is quantified. Does this perturbation result in a significant change in PAK1IP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of DDIT4. Does this perturbation cause a significant change in DDIT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of DDIT4. Does this perturbation cause a significant change in DDIT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2533,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
728,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor RP11-132A1.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-132A1.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor RP11-132A1.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-132A1.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and PIK3IP1 expression is measured. Determine whether PIK3IP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and PIK3IP1 expression is measured. Determine whether PIK3IP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of CDRT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of CDRT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of SMIM14 is measured. Determine whether SMIM14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of SMIM14 is measured. Determine whether SMIM14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and NTRK1 expression is quantified. Does this perturbation result in a significant change in NTRK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and NTRK1 expression is quantified. Does this perturbation result in a significant change in NTRK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
788,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor WHAMM expression. Decide whether this perturbation leads to a significant alteration in WHAMM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor WHAMM expression. Decide whether this perturbation leads to a significant alteration in WHAMM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of CD83 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of CD83 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
613,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and HP1BP3 expression is observed. Does this perturbation lead to a significant difference in HP1BP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and HP1BP3 expression is observed. Does this perturbation lead to a significant difference in HP1BP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of MBNL1. Does this perturbation cause a significant change in MBNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of MBNL1. Does this perturbation cause a significant change in MBNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3878,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor C9orf64 expression. Decide whether this perturbation leads to a significant alteration in C9orf64 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor C9orf64 expression. Decide whether this perturbation leads to a significant alteration in C9orf64 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2693,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and CD83 expression is observed. Does this perturbation lead to a significant difference in CD83 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and CD83 expression is observed. Does this perturbation lead to a significant difference in CD83 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of SNHG7 is measured. Determine whether SNHG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of SNHG7 is measured. Determine whether SNHG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
188,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor STC2 expression. Decide whether this perturbation leads to a significant alteration in STC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor STC2 expression. Decide whether this perturbation leads to a significant alteration in STC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1408,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor GUSB expression. Decide whether this perturbation leads to a significant alteration in GUSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor GUSB expression. Decide whether this perturbation leads to a significant alteration in GUSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of LRIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of LRIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of RP11-381O7.3. Does this perturbation cause a significant change in RP11-381O7.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of RP11-381O7.3. Does this perturbation cause a significant change in RP11-381O7.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of SPEN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of SPEN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
5158,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor ROCK1 expression. Decide whether this perturbation leads to a significant alteration in ROCK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor ROCK1 expression. Decide whether this perturbation leads to a significant alteration in ROCK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of FCGRT is measured. Determine whether FCGRT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of FCGRT is measured. Determine whether FCGRT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of C17orf64 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of C17orf64 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
860,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of ESCO1 is measured. Does this perturbation cause a significant change in ESCO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of ESCO1 is measured. Does this perturbation cause a significant change in ESCO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4523,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and ATF7IP2 expression is observed. Does this perturbation lead to a significant difference in ATF7IP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and ATF7IP2 expression is observed. Does this perturbation lead to a significant difference in ATF7IP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3030,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of RP11-838N2.4 is measured. Does this perturbation cause a significant change in RP11-838N2.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of RP11-838N2.4 is measured. Does this perturbation cause a significant change in RP11-838N2.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in PTPRC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in PTPRC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of TNFRSF10B. Does this perturbation cause a significant change in TNFRSF10B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of TNFRSF10B. Does this perturbation cause a significant change in TNFRSF10B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
4801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of EIF3A. Does perturbing XRN1 lead to a significant change in EIF3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of EIF3A. Does perturbing XRN1 lead to a significant change in EIF3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
4397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of ATAD2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of ATAD2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
4715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in TAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in TAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1360,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of ZNF678 is measured. Does this perturbation cause a significant change in ZNF678 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of ZNF678 is measured. Does this perturbation cause a significant change in ZNF678 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3160,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of MT2A is measured. Does this perturbation cause a significant change in MT2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of MT2A is measured. Does this perturbation cause a significant change in MT2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of SLC37A1. Does perturbing UFL1 lead to a significant change in SLC37A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of SLC37A1. Does perturbing UFL1 lead to a significant change in SLC37A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1040,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of HRK is measured. Does this perturbation cause a significant change in HRK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of HRK is measured. Does this perturbation cause a significant change in HRK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and SHOX2 expression is measured. Determine whether SHOX2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and SHOX2 expression is measured. Determine whether SHOX2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and DUT expression is measured. Determine whether DUT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and DUT expression is measured. Determine whether DUT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and ERP29 expression is measured. Determine whether ERP29 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and ERP29 expression is measured. Determine whether ERP29 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
170,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of TKTL1 is measured. Does this perturbation cause a significant change in TKTL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of TKTL1 is measured. Does this perturbation cause a significant change in TKTL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3703,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and PARP11 expression is observed. Does this perturbation lead to a significant difference in PARP11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and PARP11 expression is observed. Does this perturbation lead to a significant difference in PARP11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of CLDN11 is measured. Determine whether CLDN11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of CLDN11 is measured. Determine whether CLDN11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in C1GALT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in C1GALT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
5159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and ROCK1 expression is measured. Determine whether ROCK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and ROCK1 expression is measured. Determine whether ROCK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of LTBP1. Does this perturbation cause a significant change in LTBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of LTBP1. Does this perturbation cause a significant change in LTBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in MYH7B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in MYH7B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3393,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and TUBA1C expression is observed. Does this perturbation lead to a significant difference in TUBA1C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and TUBA1C expression is observed. Does this perturbation lead to a significant difference in TUBA1C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
4920,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of YTHDF2 is measured. Does this perturbation cause a significant change in YTHDF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of YTHDF2 is measured. Does this perturbation cause a significant change in YTHDF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RP11-685N10.1 expression is measured. Determine whether RP11-685N10.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RP11-685N10.1 expression is measured. Determine whether RP11-685N10.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and RGS3 expression is quantified. Does this perturbation result in a significant change in RGS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and RGS3 expression is quantified. Does this perturbation result in a significant change in RGS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and RP11-81A22.5 expression is measured. Determine whether RP11-81A22.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and RP11-81A22.5 expression is measured. Determine whether RP11-81A22.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
4295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in RP11-360L9.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in RP11-360L9.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
4290,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of RP11-360L9.8 is measured. Does this perturbation cause a significant change in RP11-360L9.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of RP11-360L9.8 is measured. Does this perturbation cause a significant change in RP11-360L9.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
4833,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and RP11-390B4.5 expression is observed. Does this perturbation lead to a significant difference in RP11-390B4.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and RP11-390B4.5 expression is observed. Does this perturbation lead to a significant difference in RP11-390B4.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of SETX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of SETX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of RP11-212I21.4. Does this perturbation cause a significant change in RP11-212I21.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of RP11-212I21.4. Does this perturbation cause a significant change in RP11-212I21.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in PDK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in PDK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."