[
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and NAV1 expression is observed. Does this perturbation lead to a significant difference in NAV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and NAV1 expression is observed. Does this perturbation lead to a significant difference in NAV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4463
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of ATP6V1B2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of ATP6V1B2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1607
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of RP13-216E22.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of RP13-216E22.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2437
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of RGS3. Does this perturbation cause a significant change in RGS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of RGS3. Does this perturbation cause a significant change in RGS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2874
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and STK17B expression is measured. Determine whether STK17B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and STK17B expression is measured. Determine whether STK17B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4859
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor RP11-435O5.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-435O5.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor RP11-435O5.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-435O5.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1198
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and FAM114A1 expression is observed. Does this perturbation lead to a significant difference in FAM114A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and FAM114A1 expression is observed. Does this perturbation lead to a significant difference in FAM114A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":713
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in PKDCC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in PKDCC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1795
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in IDS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in IDS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4275
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of APOBEC3D is measured. Does this perturbation cause a significant change in APOBEC3D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of APOBEC3D is measured. Does this perturbation cause a significant change in APOBEC3D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3570
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of TOPBP1 is measured. Determine whether TOPBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of TOPBP1 is measured. Determine whether TOPBP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3806
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in KCNJ13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in KCNJ13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3655
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in NFE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in NFE2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":215
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PHF19. Does perturbing SARS lead to a significant change in PHF19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PHF19. Does perturbing SARS lead to a significant change in PHF19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3061
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of UHRF1BP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of UHRF1BP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":247
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor ITGB2 expression. Decide whether this perturbation leads to a significant alteration in ITGB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor ITGB2 expression. Decide whether this perturbation leads to a significant alteration in ITGB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1308
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of TGOLN2. Does perturbing SPCS3 lead to a significant change in TGOLN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of TGOLN2. Does perturbing SPCS3 lead to a significant change in TGOLN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5091
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and CASP8 expression is observed. Does this perturbation lead to a significant difference in CASP8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and CASP8 expression is observed. Does this perturbation lead to a significant difference in CASP8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":223
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of ERV3-1. Does this perturbation cause a significant change in ERV3-1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of ERV3-1. Does this perturbation cause a significant change in ERV3-1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":464
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of HAGH. Does perturbing SEC63 lead to a significant change in HAGH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of HAGH. Does perturbing SEC63 lead to a significant change in HAGH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2631
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in ATAD2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in ATAD2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4395
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in BAMBI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in BAMBI expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1275
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ZFP36L2 is measured. Determine whether ZFP36L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ZFP36L2 is measured. Determine whether ZFP36L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3456
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in VIM-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in VIM-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1725
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":310
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of ANKRD11. Does this perturbation cause a significant change in ANKRD11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of ANKRD11. Does this perturbation cause a significant change in ANKRD11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4694
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of TROAP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of TROAP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3087
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and SNRNP25 expression is measured. Determine whether SNRNP25 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and SNRNP25 expression is measured. Determine whether SNRNP25 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2159
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of LAMP2 is measured. Does this perturbation cause a significant change in LAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of LAMP2 is measured. Does this perturbation cause a significant change in LAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5040
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of YTHDF2. Does this perturbation cause a significant change in YTHDF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of YTHDF2. Does this perturbation cause a significant change in YTHDF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4924
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of CRNDE. Does this perturbation cause a significant change in CRNDE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of CRNDE. Does this perturbation cause a significant change in CRNDE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1974
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of CTD-2267D19.3. Does perturbing SEL1L lead to a significant change in CTD-2267D19.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of CTD-2267D19.3. Does perturbing SEL1L lead to a significant change in CTD-2267D19.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1541
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and TACC3 expression is observed. Does this perturbation lead to a significant difference in TACC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and TACC3 expression is observed. Does this perturbation lead to a significant difference in TACC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1863
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of NBEAL2. Does perturbing ZNF326 lead to a significant change in NBEAL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of NBEAL2. Does perturbing ZNF326 lead to a significant change in NBEAL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PIF1 expression. Decide whether this perturbation leads to a significant alteration in PIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PIF1 expression. Decide whether this perturbation leads to a significant alteration in PIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3078
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of SEC23IP is measured. Does this perturbation cause a significant change in SEC23IP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of SEC23IP is measured. Does this perturbation cause a significant change in SEC23IP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3970
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of EPS15 is measured. Determine whether EPS15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of EPS15 is measured. Determine whether EPS15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4846
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of GATA2 is measured. Does this perturbation cause a significant change in GATA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of GATA2 is measured. Does this perturbation cause a significant change in GATA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5110
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ROBO1. Does perturbing SLC35B1 lead to a significant change in ROBO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ROBO1. Does perturbing SLC35B1 lead to a significant change in ROBO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3941
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and RP11-390B4.5 expression is quantified. Does this perturbation result in a significant change in RP11-390B4.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and RP11-390B4.5 expression is quantified. Does this perturbation result in a significant change in RP11-390B4.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4832
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of LTB is measured. Does this perturbation cause a significant change in LTB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of LTB is measured. Does this perturbation cause a significant change in LTB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4700
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in TIPARP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in TIPARP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3615
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in KCNQ1OT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in KCNQ1OT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4625
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of SETX. Does this perturbation cause a significant change in SETX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of SETX. Does this perturbation cause a significant change in SETX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2474
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in ACRV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in ACRV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3895
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of PLA2G15 is measured. Determine whether PLA2G15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of PLA2G15 is measured. Determine whether PLA2G15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3836
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PSMD14 expression. Decide whether this perturbation leads to a significant alteration in PSMD14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PSMD14 expression. Decide whether this perturbation leads to a significant alteration in PSMD14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3108
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor CASP4 expression. Decide whether this perturbation leads to a significant alteration in CASP4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor CASP4 expression. Decide whether this perturbation leads to a significant alteration in CASP4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of RP13-216E22.4 is measured. Determine whether RP13-216E22.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of RP13-216E22.4 is measured. Determine whether RP13-216E22.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2436
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and MS4A6E expression is quantified. Does this perturbation result in a significant change in MS4A6E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and MS4A6E expression is quantified. Does this perturbation result in a significant change in MS4A6E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":342
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and KCNQ1OT1 expression is observed. Does this perturbation lead to a significant difference in KCNQ1OT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and KCNQ1OT1 expression is observed. Does this perturbation lead to a significant difference in KCNQ1OT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4623
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in ZMYND8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in ZMYND8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1525
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and CLINT1 expression is measured. Determine whether CLINT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and CLINT1 expression is measured. Determine whether CLINT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":439
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of ZNF292. Does this perturbation cause a significant change in ZNF292 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of ZNF292. Does this perturbation cause a significant change in ZNF292 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3564
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in PTGS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in PTGS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3485
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of KIAA1731. Does this perturbation cause a significant change in KIAA1731 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of KIAA1731. Does this perturbation cause a significant change in KIAA1731 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4894
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of HLA-AS1 is measured. Determine whether HLA-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of HLA-AS1 is measured. Determine whether HLA-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":766
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of TSPAN33 is measured. Does this perturbation cause a significant change in TSPAN33 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of TSPAN33 is measured. Does this perturbation cause a significant change in TSPAN33 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3520
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in LTBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in LTBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1805
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of LDLR is measured. Determine whether LDLR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of LDLR is measured. Determine whether LDLR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":496
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and TRIM38 expression is measured. Determine whether TRIM38 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and TRIM38 expression is measured. Determine whether TRIM38 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3389
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and RP11-81A22.5 expression is quantified. Does this perturbation result in a significant change in RP11-81A22.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and RP11-81A22.5 expression is quantified. Does this perturbation result in a significant change in RP11-81A22.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1612
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in ANPEP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in ANPEP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4795
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and ARHGAP6 expression is observed. Does this perturbation lead to a significant difference in ARHGAP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and ARHGAP6 expression is observed. Does this perturbation lead to a significant difference in ARHGAP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1753
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor SSBP2 expression. Decide whether this perturbation leads to a significant alteration in SSBP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor SSBP2 expression. Decide whether this perturbation leads to a significant alteration in SSBP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4168
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of AMOTL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of AMOTL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2247
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and C17orf64 expression is quantified. Does this perturbation result in a significant change in C17orf64 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and C17orf64 expression is quantified. Does this perturbation result in a significant change in C17orf64 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3712
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of PDRG1. Does this perturbation cause a significant change in PDRG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of PDRG1. Does this perturbation cause a significant change in PDRG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4154
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of HP1BP3. Does this perturbation cause a significant change in HP1BP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of HP1BP3. Does this perturbation cause a significant change in HP1BP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":614
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of HLA-AS1 is measured. Does this perturbation cause a significant change in HLA-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of HLA-AS1 is measured. Does this perturbation cause a significant change in HLA-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":760
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in ZFHX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4285
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of USP34 is measured. Determine whether USP34 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of USP34 is measured. Determine whether USP34 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4366
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RP11-685N10.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-685N10.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RP11-685N10.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-685N10.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2758
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and CD9 expression is quantified. Does this perturbation result in a significant change in CD9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and CD9 expression is quantified. Does this perturbation result in a significant change in CD9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":422
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of ESCO1 is measured. Determine whether ESCO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of ESCO1 is measured. Determine whether ESCO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":866
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor ARHGAP30 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP30 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor ARHGAP30 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP30 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1478
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and MORF4L2 expression is quantified. Does this perturbation result in a significant change in MORF4L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and MORF4L2 expression is quantified. Does this perturbation result in a significant change in MORF4L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2622
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of RP11-363D14.1 is measured. Determine whether RP11-363D14.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of RP11-363D14.1 is measured. Determine whether RP11-363D14.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3056
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor ATP5EP2 expression. Decide whether this perturbation leads to a significant alteration in ATP5EP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor ATP5EP2 expression. Decide whether this perturbation leads to a significant alteration in ATP5EP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2958
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of POLR2J3 is measured. Determine whether POLR2J3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of POLR2J3 is measured. Determine whether POLR2J3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3796
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and RP11-132A1.4 expression is quantified. Does this perturbation result in a significant change in RP11-132A1.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and RP11-132A1.4 expression is quantified. Does this perturbation result in a significant change in RP11-132A1.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":722
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in ZNF678 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in ZNF678 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1365
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and MT2A expression is measured. Determine whether MT2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and MT2A expression is measured. Determine whether MT2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3169
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of RGS20. Does perturbing TMED2 lead to a significant change in RGS20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of RGS20. Does perturbing TMED2 lead to a significant change in RGS20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4941
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and WARS expression is observed. Does this perturbation lead to a significant difference in WARS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and WARS expression is observed. Does this perturbation lead to a significant difference in WARS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4883
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of RP11-423O2.5. Does perturbing SEC61A1 lead to a significant change in RP11-423O2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of RP11-423O2.5. Does perturbing SEC61A1 lead to a significant change in RP11-423O2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":301
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in AC096559.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in AC096559.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1875
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and C12orf23 expression is observed. Does this perturbation lead to a significant difference in C12orf23 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and C12orf23 expression is observed. Does this perturbation lead to a significant difference in C12orf23 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1763
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of TET1 is measured. Determine whether TET1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of TET1 is measured. Determine whether TET1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":136
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and LRRC4B expression is observed. Does this perturbation lead to a significant difference in LRRC4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and LRRC4B expression is observed. Does this perturbation lead to a significant difference in LRRC4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2173
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in IL13RA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in IL13RA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2355
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ROBO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ROBO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3945
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and SPAST expression is quantified. Does this perturbation result in a significant change in SPAST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and SPAST expression is quantified. Does this perturbation result in a significant change in SPAST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":922
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and RNF8 expression is quantified. Does this perturbation result in a significant change in RNF8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and RNF8 expression is quantified. Does this perturbation result in a significant change in RNF8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3182
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of DNMBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of DNMBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4017
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and PGM3 expression is quantified. Does this perturbation result in a significant change in PGM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and PGM3 expression is quantified. Does this perturbation result in a significant change in PGM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2082
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of SPAST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of SPAST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2847
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of C3AR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of C3AR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3407
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor RILPL2 expression. Decide whether this perturbation leads to a significant alteration in RILPL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor RILPL2 expression. Decide whether this perturbation leads to a significant alteration in RILPL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4148
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of RAD51AP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of RAD51AP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5147
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor SPEN expression. Decide whether this perturbation leads to a significant alteration in SPEN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor SPEN expression. Decide whether this perturbation leads to a significant alteration in SPEN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1578
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and GATA3 expression is quantified. Does this perturbation result in a significant change in GATA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and GATA3 expression is quantified. Does this perturbation result in a significant change in GATA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":882
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of HRK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of HRK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1047
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of PBDC1. Does perturbing HARS lead to a significant change in PBDC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of PBDC1. Does perturbing HARS lead to a significant change in PBDC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":601
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and CLDN11 expression is measured. Determine whether CLDN11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and CLDN11 expression is measured. Determine whether CLDN11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4549
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of PAK1IP1. Does perturbing CHERP lead to a significant change in PAK1IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of PAK1IP1. Does perturbing CHERP lead to a significant change in PAK1IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4251
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and NOX5 expression is quantified. Does this perturbation result in a significant change in NOX5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and NOX5 expression is quantified. Does this perturbation result in a significant change in NOX5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3412
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of GATA2. Does this perturbation cause a significant change in GATA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of GATA2. Does this perturbation cause a significant change in GATA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5114
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and UHRF1BP1L expression is measured. Determine whether UHRF1BP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and UHRF1BP1L expression is measured. Determine whether UHRF1BP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":249
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and TMEM60 expression is quantified. Does this perturbation result in a significant change in TMEM60 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and TMEM60 expression is quantified. Does this perturbation result in a significant change in TMEM60 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4972
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4753
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and CENPF expression is quantified. Does this perturbation result in a significant change in CENPF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and CENPF expression is quantified. Does this perturbation result in a significant change in CENPF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4062
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of MLEC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of MLEC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3177
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of AC018878.3 is measured. Does this perturbation cause a significant change in AC018878.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of AC018878.3 is measured. Does this perturbation cause a significant change in AC018878.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3280
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in TKTL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in TKTL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":175
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of SBF2. Does this perturbation cause a significant change in SBF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of SBF2. Does this perturbation cause a significant change in SBF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2564
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of RILPL2 is measured. Determine whether RILPL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of RILPL2 is measured. Determine whether RILPL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4146
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and HLA-E expression is measured. Determine whether HLA-E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and HLA-E expression is measured. Determine whether HLA-E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3269
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of IL18R1. Does perturbing SEC61A1 lead to a significant change in IL18R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of IL18R1. Does perturbing SEC61A1 lead to a significant change in IL18R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":351
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of ACSM3. Does perturbing DERL2 lead to a significant change in ACSM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of ACSM3. Does perturbing DERL2 lead to a significant change in ACSM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2211
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3968
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and PCK2 expression is measured. Determine whether PCK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and PCK2 expression is measured. Determine whether PCK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3019
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of TAP1 is measured. Does this perturbation cause a significant change in TAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of TAP1 is measured. Does this perturbation cause a significant change in TAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4710
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of CDK13. Does perturbing HSD17B12 lead to a significant change in CDK13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of CDK13. Does perturbing HSD17B12 lead to a significant change in CDK13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2761
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RIOK3. Does perturbing ZNF326 lead to a significant change in RIOK3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RIOK3. Does perturbing ZNF326 lead to a significant change in RIOK3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of GMEB1. Does perturbing DDRGK1 lead to a significant change in GMEB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of GMEB1. Does perturbing DDRGK1 lead to a significant change in GMEB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1201
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of DUT. Does perturbing OST4 lead to a significant change in DUT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of DUT. Does perturbing OST4 lead to a significant change in DUT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":271
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of CLINT1 is measured. Does this perturbation cause a significant change in CLINT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of CLINT1 is measured. Does this perturbation cause a significant change in CLINT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":430
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and ZNF280B expression is quantified. Does this perturbation result in a significant change in ZNF280B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and ZNF280B expression is quantified. Does this perturbation result in a significant change in ZNF280B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1282
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of MANF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of MANF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2077
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of KLF3 is measured. Does this perturbation cause a significant change in KLF3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of KLF3 is measured. Does this perturbation cause a significant change in KLF3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1980
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and VPS41 expression is observed. Does this perturbation lead to a significant difference in VPS41 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and VPS41 expression is observed. Does this perturbation lead to a significant difference in VPS41 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":633
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of GLG1. Does this perturbation cause a significant change in GLG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of GLG1. Does this perturbation cause a significant change in GLG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1944
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in RNF139-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in RNF139-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2525
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of IDH3A is measured. Determine whether IDH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of IDH3A is measured. Determine whether IDH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2646
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of APOBEC3D. Does perturbing SRP68 lead to a significant change in APOBEC3D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of APOBEC3D. Does perturbing SRP68 lead to a significant change in APOBEC3D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3571
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of RASGRP2 is measured. Does this perturbation cause a significant change in RASGRP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of RASGRP2 is measured. Does this perturbation cause a significant change in RASGRP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4260
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RP11-65L19.4 is measured. Does this perturbation cause a significant change in RP11-65L19.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RP11-65L19.4 is measured. Does this perturbation cause a significant change in RP11-65L19.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of PSMC1 is measured. Determine whether PSMC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of PSMC1 is measured. Determine whether PSMC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2826
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of CTCFL is measured. Determine whether CTCFL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of CTCFL is measured. Determine whether CTCFL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2606
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and RPL39 expression is observed. Does this perturbation lead to a significant difference in RPL39 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and RPL39 expression is observed. Does this perturbation lead to a significant difference in RPL39 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1743
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of CTSF is measured. Does this perturbation cause a significant change in CTSF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of CTSF is measured. Does this perturbation cause a significant change in CTSF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":150
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of GATA2 is measured. Determine whether GATA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of GATA2 is measured. Determine whether GATA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5116
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ZXDA expression is quantified. Does this perturbation result in a significant change in ZXDA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ZXDA expression is quantified. Does this perturbation result in a significant change in ZXDA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3932
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and NOX5 expression is observed. Does this perturbation lead to a significant difference in NOX5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and NOX5 expression is observed. Does this perturbation lead to a significant difference in NOX5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3413
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of RP11-212I21.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of RP11-212I21.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2037
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of RP11-334C17.5. Does perturbing IDH3A lead to a significant change in RP11-334C17.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of RP11-334C17.5. Does perturbing IDH3A lead to a significant change in RP11-334C17.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1001
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and BACH2 expression is measured. Determine whether BACH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and BACH2 expression is measured. Determine whether BACH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3479
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of MANF. Does perturbing TTI2 lead to a significant change in MANF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of MANF. Does perturbing TTI2 lead to a significant change in MANF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2071
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of LINC01031 is measured. Determine whether LINC01031 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of LINC01031 is measured. Determine whether LINC01031 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4246
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of NPDC1 is measured. Does this perturbation cause a significant change in NPDC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of NPDC1 is measured. Does this perturbation cause a significant change in NPDC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1320
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor PAXBP1 expression. Decide whether this perturbation leads to a significant alteration in PAXBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor PAXBP1 expression. Decide whether this perturbation leads to a significant alteration in PAXBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4748
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor RP11-146D12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-146D12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor RP11-146D12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-146D12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":478
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor PPP4R2 expression. Decide whether this perturbation leads to a significant alteration in PPP4R2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor PPP4R2 expression. Decide whether this perturbation leads to a significant alteration in PPP4R2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2378
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and LDLR expression is measured. Determine whether LDLR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and LDLR expression is measured. Determine whether LDLR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":499
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of EP300 is measured. Determine whether EP300 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of EP300 is measured. Determine whether EP300 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2056
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of AFF1 is measured. Does this perturbation cause a significant change in AFF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of AFF1 is measured. Does this perturbation cause a significant change in AFF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2910
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor EP300 expression. Decide whether this perturbation leads to a significant alteration in EP300 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor EP300 expression. Decide whether this perturbation leads to a significant alteration in EP300 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1688
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of PKDCC is measured. Does this perturbation cause a significant change in PKDCC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of PKDCC is measured. Does this perturbation cause a significant change in PKDCC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1790
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ARHGAP6. Does perturbing SLC35B1 lead to a significant change in ARHGAP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ARHGAP6. Does perturbing SLC35B1 lead to a significant change in ARHGAP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3901
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of ZCCHC11. Does this perturbation cause a significant change in ZCCHC11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of ZCCHC11. Does this perturbation cause a significant change in ZCCHC11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4994
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor RP11-328J2.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-328J2.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor RP11-328J2.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-328J2.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1098
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of ATP6V1B2. Does this perturbation cause a significant change in ATP6V1B2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of ATP6V1B2. Does this perturbation cause a significant change in ATP6V1B2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1604
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and TRPM4 expression is observed. Does this perturbation lead to a significant difference in TRPM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and TRPM4 expression is observed. Does this perturbation lead to a significant difference in TRPM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3843
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of TRIM24. Does this perturbation cause a significant change in TRIM24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of TRIM24. Does this perturbation cause a significant change in TRIM24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3194
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of CTD-2587M2.1. Does this perturbation cause a significant change in CTD-2587M2.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of CTD-2587M2.1. Does this perturbation cause a significant change in CTD-2587M2.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1914
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in ATF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in ATF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":855
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor CENPF expression. Decide whether this perturbation leads to a significant alteration in CENPF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor CENPF expression. Decide whether this perturbation leads to a significant alteration in CENPF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4068
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of AC096559.1 is measured. Determine whether AC096559.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of AC096559.1 is measured. Determine whether AC096559.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1876
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of DYNC1H1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of DYNC1H1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3147
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and ZNF280B expression is observed. Does this perturbation lead to a significant difference in ZNF280B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and ZNF280B expression is observed. Does this perturbation lead to a significant difference in ZNF280B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1103
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ARHGAP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ARHGAP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3907
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and SETD5-AS1 expression is measured. Determine whether SETD5-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and SETD5-AS1 expression is measured. Determine whether SETD5-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1189
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and MTPN expression is measured. Determine whether MTPN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and MTPN expression is measured. Determine whether MTPN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4739
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of CDRT4. Does perturbing OST4 lead to a significant change in CDRT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of CDRT4. Does perturbing OST4 lead to a significant change in CDRT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":281
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of NOX5 is measured. Determine whether NOX5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of NOX5 is measured. Determine whether NOX5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3416
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4575
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and SSBP2 expression is measured. Determine whether SSBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and SSBP2 expression is measured. Determine whether SSBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4169
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of DSC2 is measured. Does this perturbation cause a significant change in DSC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of DSC2 is measured. Does this perturbation cause a significant change in DSC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4090
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in TRIM38 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in TRIM38 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3385
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of LTBP1 is measured. Does this perturbation cause a significant change in LTBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of LTBP1 is measured. Does this perturbation cause a significant change in LTBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1800
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of ZNF341 is measured. Determine whether ZNF341 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of ZNF341 is measured. Determine whether ZNF341 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3776
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in HIST1H3D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in HIST1H3D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":915
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in AC079466.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in AC079466.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1445
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of TMOD3. Does this perturbation cause a significant change in TMOD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of TMOD3. Does this perturbation cause a significant change in TMOD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1514
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and DOCK8 expression is measured. Determine whether DOCK8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and DOCK8 expression is measured. Determine whether DOCK8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1569
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of LTB. Does this perturbation cause a significant change in LTB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of LTB. Does this perturbation cause a significant change in LTB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":324
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of RP11-640M9.1. Does perturbing SOCS1 lead to a significant change in RP11-640M9.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of RP11-640M9.1. Does perturbing SOCS1 lead to a significant change in RP11-640M9.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1121
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and NUF2 expression is observed. Does this perturbation lead to a significant difference in NUF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and NUF2 expression is observed. Does this perturbation lead to a significant difference in NUF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1393
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of PCK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of PCK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":337
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of RSAD2. Does perturbing FECH lead to a significant change in RSAD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of RSAD2. Does perturbing FECH lead to a significant change in RSAD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4401
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in RP11-640M9.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in RP11-640M9.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1125
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of RP11-157D23.2 is measured. Determine whether RP11-157D23.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of RP11-157D23.2 is measured. Determine whether RP11-157D23.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4426
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of TGOLN2. Does this perturbation cause a significant change in TGOLN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of TGOLN2. Does this perturbation cause a significant change in TGOLN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5094
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of CTD-2001C12.1 is measured. Does this perturbation cause a significant change in CTD-2001C12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of CTD-2001C12.1 is measured. Does this perturbation cause a significant change in CTD-2001C12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":570
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of HLTF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of HLTF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2487
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of CHD3. Does perturbing CARS lead to a significant change in CHD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of CHD3. Does perturbing CARS lead to a significant change in CHD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4901
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in GRN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in GRN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4335
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of EP400 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of EP400 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3667
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of SHOX2 is measured. Determine whether SHOX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of SHOX2 is measured. Determine whether SHOX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":996
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of TSNAXIP1 is measured. Does this perturbation cause a significant change in TSNAXIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of TSNAXIP1 is measured. Does this perturbation cause a significant change in TSNAXIP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":750
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and IL18R1 expression is observed. Does this perturbation lead to a significant difference in IL18R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and IL18R1 expression is observed. Does this perturbation lead to a significant difference in IL18R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4203
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of HIST1H1E is measured. Does this perturbation cause a significant change in HIST1H1E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of HIST1H1E is measured. Does this perturbation cause a significant change in HIST1H1E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1020
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of SRP72 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of SRP72 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1237
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of C6orf120 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of C6orf120 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2267
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of IFT27. Does perturbing CHERP lead to a significant change in IFT27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of IFT27. Does perturbing CHERP lead to a significant change in IFT27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4221
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of IFNGR1 is measured. Determine whether IFNGR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of IFNGR1 is measured. Determine whether IFNGR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2656
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of PPM1N is measured. Does this perturbation cause a significant change in PPM1N expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of PPM1N is measured. Does this perturbation cause a significant change in PPM1N expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3920
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of ABI2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of ABI2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2027
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in VIMP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in VIMP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4585
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of IL2RB is measured. Determine whether IL2RB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of IL2RB is measured. Determine whether IL2RB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3606
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and SPEN expression is observed. Does this perturbation lead to a significant difference in SPEN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and SPEN expression is observed. Does this perturbation lead to a significant difference in SPEN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4083
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and SNHG7 expression is measured. Determine whether SNHG7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and SNHG7 expression is measured. Determine whether SNHG7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4049
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of VAMP2 is measured. Does this perturbation cause a significant change in VAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of VAMP2 is measured. Does this perturbation cause a significant change in VAMP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2900
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ROBO1 expression is quantified. Does this perturbation result in a significant change in ROBO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ROBO1 expression is quantified. Does this perturbation result in a significant change in ROBO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3942
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of AC018878.3. Does this perturbation cause a significant change in AC018878.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of AC018878.3. Does this perturbation cause a significant change in AC018878.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3284
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of RP11-434H6.6 is measured. Determine whether RP11-434H6.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of RP11-434H6.6 is measured. Determine whether RP11-434H6.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1896
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor CENPC expression. Decide whether this perturbation leads to a significant alteration in CENPC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor CENPC expression. Decide whether this perturbation leads to a significant alteration in CENPC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2188
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and KIAA0922 expression is observed. Does this perturbation lead to a significant difference in KIAA0922 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and KIAA0922 expression is observed. Does this perturbation lead to a significant difference in KIAA0922 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3743
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in EP300 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in EP300 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2055
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor ACRV1 expression. Decide whether this perturbation leads to a significant alteration in ACRV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor ACRV1 expression. Decide whether this perturbation leads to a significant alteration in ACRV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3898
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and LTN1 expression is quantified. Does this perturbation result in a significant change in LTN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and LTN1 expression is quantified. Does this perturbation result in a significant change in LTN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3782
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and QSER1 expression is observed. Does this perturbation lead to a significant difference in QSER1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and QSER1 expression is observed. Does this perturbation lead to a significant difference in QSER1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3003
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of IFT27. Does this perturbation cause a significant change in IFT27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of IFT27. Does this perturbation cause a significant change in IFT27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4224
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of ERV3-1 is measured. Does this perturbation cause a significant change in ERV3-1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of ERV3-1 is measured. Does this perturbation cause a significant change in ERV3-1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":460
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of DNASE2 is measured. Determine whether DNASE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of DNASE2 is measured. Determine whether DNASE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1636
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in RILPL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in RILPL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4145
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of KCNH7 is measured. Does this perturbation cause a significant change in KCNH7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of KCNH7 is measured. Does this perturbation cause a significant change in KCNH7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1780
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor RP11-242O24.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-242O24.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor RP11-242O24.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-242O24.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3998
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of ASPM. Does perturbing MANF lead to a significant change in ASPM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of ASPM. Does perturbing MANF lead to a significant change in ASPM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2661
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor TMOD3 expression. Decide whether this perturbation leads to a significant alteration in TMOD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor TMOD3 expression. Decide whether this perturbation leads to a significant alteration in TMOD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1518
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and KLF3 expression is quantified. Does this perturbation result in a significant change in KLF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and KLF3 expression is quantified. Does this perturbation result in a significant change in KLF3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1982
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor AC007038.7 expression. Decide whether this perturbation leads to a significant alteration in AC007038.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor AC007038.7 expression. Decide whether this perturbation leads to a significant alteration in AC007038.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2928
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and CRNDE expression is quantified. Does this perturbation result in a significant change in CRNDE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and CRNDE expression is quantified. Does this perturbation result in a significant change in CRNDE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1972
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ZFP36L2 is measured. Does this perturbation cause a significant change in ZFP36L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ZFP36L2 is measured. Does this perturbation cause a significant change in ZFP36L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3450
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and CTD-2521M24.9 expression is observed. Does this perturbation lead to a significant difference in CTD-2521M24.9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and CTD-2521M24.9 expression is observed. Does this perturbation lead to a significant difference in CTD-2521M24.9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2993
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of RP11-242O24.5 is measured. Determine whether RP11-242O24.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of RP11-242O24.5 is measured. Determine whether RP11-242O24.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3996
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of LTN1. Does perturbing ARHGAP22 lead to a significant change in LTN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of LTN1. Does perturbing ARHGAP22 lead to a significant change in LTN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3131
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and BACH2 expression is observed. Does this perturbation lead to a significant difference in BACH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and BACH2 expression is observed. Does this perturbation lead to a significant difference in BACH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3473
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of FAM212A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of FAM212A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2237
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of C12orf23 is measured. Determine whether C12orf23 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of C12orf23 is measured. Determine whether C12orf23 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1766
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in HLTF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in HLTF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2485
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and RILPL2 expression is observed. Does this perturbation lead to a significant difference in RILPL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and RILPL2 expression is observed. Does this perturbation lead to a significant difference in RILPL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2803
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of HIST1H1D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of HIST1H1D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4347
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of LIMS1. Does perturbing SRP72 lead to a significant change in LIMS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of LIMS1. Does perturbing SRP72 lead to a significant change in LIMS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3371
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor NXF1 expression. Decide whether this perturbation leads to a significant alteration in NXF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor NXF1 expression. Decide whether this perturbation leads to a significant alteration in NXF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3118
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in TET1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in TET1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":135
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of ZMYND8. Does this perturbation cause a significant change in ZMYND8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of ZMYND8. Does this perturbation cause a significant change in ZMYND8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1524
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and RP11-863K10.7 expression is quantified. Does this perturbation result in a significant change in RP11-863K10.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and RP11-863K10.7 expression is quantified. Does this perturbation result in a significant change in RP11-863K10.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":932
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of H1FX is measured. Does this perturbation cause a significant change in H1FX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of H1FX is measured. Does this perturbation cause a significant change in H1FX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4670
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of WARS. Does perturbing CARS lead to a significant change in WARS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of WARS. Does perturbing CARS lead to a significant change in WARS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4881
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":316
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and NPDC1 expression is measured. Determine whether NPDC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and NPDC1 expression is measured. Determine whether NPDC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1329
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of PAXBP1 is measured. Does this perturbation cause a significant change in PAXBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of PAXBP1 is measured. Does this perturbation cause a significant change in PAXBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4740
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and RP11-61E11.1 expression is quantified. Does this perturbation result in a significant change in RP11-61E11.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and RP11-61E11.1 expression is quantified. Does this perturbation result in a significant change in RP11-61E11.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1422
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in TTC18 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in TTC18 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3695
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor ZNF341 expression. Decide whether this perturbation leads to a significant alteration in ZNF341 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor ZNF341 expression. Decide whether this perturbation leads to a significant alteration in ZNF341 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3778
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3077
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and TFPI expression is quantified. Does this perturbation result in a significant change in TFPI expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and TFPI expression is quantified. Does this perturbation result in a significant change in TFPI expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3912
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of ANKLE2. Does perturbing TELO2 lead to a significant change in ANKLE2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of ANKLE2. Does perturbing TELO2 lead to a significant change in ANKLE2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2311
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and AC079466.1 expression is observed. Does this perturbation lead to a significant difference in AC079466.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and AC079466.1 expression is observed. Does this perturbation lead to a significant difference in AC079466.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1443
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in AC015987.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in AC015987.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2015
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and RP11-254F7.4 expression is measured. Determine whether RP11-254F7.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and RP11-254F7.4 expression is measured. Determine whether RP11-254F7.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2399
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and ERV3-1 expression is quantified. Does this perturbation result in a significant change in ERV3-1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and ERV3-1 expression is quantified. Does this perturbation result in a significant change in ERV3-1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":462
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of RPL39. Does perturbing MTHFD1 lead to a significant change in RPL39 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of RPL39. Does perturbing MTHFD1 lead to a significant change in RPL39 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1741
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RAI14 is measured. Does this perturbation cause a significant change in RAI14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of RAI14 is measured. Does this perturbation cause a significant change in RAI14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2700
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of S100A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of S100A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3257
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of MS4A6E is measured. Determine whether MS4A6E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of MS4A6E is measured. Determine whether MS4A6E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":346
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and C6orf48 expression is observed. Does this perturbation lead to a significant difference in C6orf48 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and C6orf48 expression is observed. Does this perturbation lead to a significant difference in C6orf48 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of NAV2 is measured. Determine whether NAV2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of NAV2 is measured. Determine whether NAV2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4866
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of NUF2. Does perturbing SAMM50 lead to a significant change in NUF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of NUF2. Does perturbing SAMM50 lead to a significant change in NUF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1391
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and RP11-445H22.3 expression is quantified. Does this perturbation result in a significant change in RP11-445H22.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and RP11-445H22.3 expression is quantified. Does this perturbation result in a significant change in RP11-445H22.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3812
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of TSNAXIP1. Does perturbing DAD1 lead to a significant change in TSNAXIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of TSNAXIP1. Does perturbing DAD1 lead to a significant change in TSNAXIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":751
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in RP11-573D15.9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in RP11-573D15.9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1295
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and RP3-465N24.6 expression is measured. Determine whether RP3-465N24.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and RP3-465N24.6 expression is measured. Determine whether RP3-465N24.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3589
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of PHLDA2. Does perturbing COPZ1 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of PHLDA2. Does perturbing COPZ1 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4571
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of NUFIP2 is measured. Does this perturbation cause a significant change in NUFIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of NUFIP2 is measured. Does this perturbation cause a significant change in NUFIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2460
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and PBDC1 expression is observed. Does this perturbation lead to a significant difference in PBDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and PBDC1 expression is observed. Does this perturbation lead to a significant difference in PBDC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":603
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and KIAA1432 expression is observed. Does this perturbation lead to a significant difference in KIAA1432 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and KIAA1432 expression is observed. Does this perturbation lead to a significant difference in KIAA1432 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3753
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of RSL24D1 is measured. Does this perturbation cause a significant change in RSL24D1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of RSL24D1 is measured. Does this perturbation cause a significant change in RSL24D1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":870
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of SPAST. Does this perturbation cause a significant change in SPAST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of SPAST. Does this perturbation cause a significant change in SPAST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":924
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in CST7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in CST7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2205
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of AKAP11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of AKAP11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1927
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and CDCA3 expression is quantified. Does this perturbation result in a significant change in CDCA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and CDCA3 expression is quantified. Does this perturbation result in a significant change in CDCA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4112
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of RP11-363D14.1 is measured. Does this perturbation cause a significant change in RP11-363D14.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of RP11-363D14.1 is measured. Does this perturbation cause a significant change in RP11-363D14.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3050
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of SPAST is measured. Does this perturbation cause a significant change in SPAST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of SPAST is measured. Does this perturbation cause a significant change in SPAST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":920
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of RILPL2. Does this perturbation cause a significant change in RILPL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of RILPL2. Does this perturbation cause a significant change in RILPL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4144
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor AC015987.2 expression. Decide whether this perturbation leads to a significant alteration in AC015987.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor AC015987.2 expression. Decide whether this perturbation leads to a significant alteration in AC015987.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2018
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of MORC2-AS1 is measured. Does this perturbation cause a significant change in MORC2-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of MORC2-AS1 is measured. Does this perturbation cause a significant change in MORC2-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2550
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and S100A10 expression is measured. Determine whether S100A10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and S100A10 expression is measured. Determine whether S100A10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4879
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in AC012594.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in AC012594.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1675
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of SNHG7. Does perturbing CCND3 lead to a significant change in SNHG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of SNHG7. Does perturbing CCND3 lead to a significant change in SNHG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4041
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of PKDCC. Does perturbing MTHFD1 lead to a significant change in PKDCC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of PKDCC. Does perturbing MTHFD1 lead to a significant change in PKDCC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1791
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and APOL4 expression is observed. Does this perturbation lead to a significant difference in APOL4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and APOL4 expression is observed. Does this perturbation lead to a significant difference in APOL4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":893
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of UHRF1BP1L. Does perturbing OST4 lead to a significant change in UHRF1BP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of UHRF1BP1L. Does perturbing OST4 lead to a significant change in UHRF1BP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":241
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of STC2. Does this perturbation cause a significant change in STC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of STC2. Does this perturbation cause a significant change in STC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":184
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and AFF1 expression is observed. Does this perturbation lead to a significant difference in AFF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and AFF1 expression is observed. Does this perturbation lead to a significant difference in AFF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2913
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and PHF21A expression is quantified. Does this perturbation result in a significant change in PHF21A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and PHF21A expression is quantified. Does this perturbation result in a significant change in PHF21A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3852
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of IDH3A is measured. Does this perturbation cause a significant change in IDH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of IDH3A is measured. Does this perturbation cause a significant change in IDH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2640
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of RILPL2. Does perturbing COPB1 lead to a significant change in RILPL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of RILPL2. Does perturbing COPB1 lead to a significant change in RILPL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4141
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of OXLD1. Does this perturbation cause a significant change in OXLD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of OXLD1. Does this perturbation cause a significant change in OXLD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2854
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of ARHGDIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of ARHGDIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1967
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of RP11-863K10.7 is measured. Does this perturbation cause a significant change in RP11-863K10.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of RP11-863K10.7 is measured. Does this perturbation cause a significant change in RP11-863K10.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":930
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor LTB expression. Decide whether this perturbation leads to a significant alteration in LTB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor LTB expression. Decide whether this perturbation leads to a significant alteration in LTB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":328
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2738
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in CD83 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in CD83 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2695
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1696
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of TLK2. Does this perturbation cause a significant change in TLK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of TLK2. Does this perturbation cause a significant change in TLK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4764
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of ARHGDIB. Does this perturbation cause a significant change in ARHGDIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of ARHGDIB. Does this perturbation cause a significant change in ARHGDIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1964
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of ZMYND8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of ZMYND8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1527
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of SHOX2. Does perturbing IDH3A lead to a significant change in SHOX2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of SHOX2. Does perturbing IDH3A lead to a significant change in SHOX2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":991
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and NRIP1 expression is measured. Determine whether NRIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and NRIP1 expression is measured. Determine whether NRIP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":129
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of ZNF789. Does this perturbation cause a significant change in ZNF789 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of ZNF789. Does this perturbation cause a significant change in ZNF789 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3224
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of LRRC4B. Does this perturbation cause a significant change in LRRC4B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of LRRC4B. Does this perturbation cause a significant change in LRRC4B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2174
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of SEC23IP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of SEC23IP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3977
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of SRP72. Does perturbing DDRGK1 lead to a significant change in SRP72 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of SRP72. Does perturbing DDRGK1 lead to a significant change in SRP72 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1231
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of SETX is measured. Does this perturbation cause a significant change in SETX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of SETX is measured. Does this perturbation cause a significant change in SETX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3360
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and RP11-95O2.5 expression is measured. Determine whether RP11-95O2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and RP11-95O2.5 expression is measured. Determine whether RP11-95O2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4479
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of NBEAL2 is measured. Does this perturbation cause a significant change in NBEAL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of NBEAL2 is measured. Does this perturbation cause a significant change in NBEAL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in EPB42 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in EPB42 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1715
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of RP11-15E18.1. Does perturbing CCND3 lead to a significant change in RP11-15E18.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of RP11-15E18.1. Does perturbing CCND3 lead to a significant change in RP11-15E18.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4051
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of KIF4A. Does perturbing SEC63 lead to a significant change in KIF4A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of KIF4A. Does perturbing SEC63 lead to a significant change in KIF4A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2581
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of S100A11. Does perturbing HSPA5 lead to a significant change in S100A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of S100A11. Does perturbing HSPA5 lead to a significant change in S100A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3251
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and LRRC4B expression is quantified. Does this perturbation result in a significant change in LRRC4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and LRRC4B expression is quantified. Does this perturbation result in a significant change in LRRC4B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2172
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and SLBP expression is observed. Does this perturbation lead to a significant difference in SLBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and SLBP expression is observed. Does this perturbation lead to a significant difference in SLBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2133
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of AC012594.1 is measured. Does this perturbation cause a significant change in AC012594.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of AC012594.1 is measured. Does this perturbation cause a significant change in AC012594.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1670
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and NUFIP2 expression is observed. Does this perturbation lead to a significant difference in NUFIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and NUFIP2 expression is observed. Does this perturbation lead to a significant difference in NUFIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2463
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of DOCK8 is measured. Determine whether DOCK8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of DOCK8 is measured. Determine whether DOCK8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1566
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of ZNF280B is measured. Determine whether ZNF280B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of ZNF280B is measured. Determine whether ZNF280B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1286
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and TRAPPC10 expression is quantified. Does this perturbation result in a significant change in TRAPPC10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and TRAPPC10 expression is quantified. Does this perturbation result in a significant change in TRAPPC10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1852
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor IDH3A expression. Decide whether this perturbation leads to a significant alteration in IDH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor IDH3A expression. Decide whether this perturbation leads to a significant alteration in IDH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2648
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of RSAD2. Does this perturbation cause a significant change in RSAD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of RSAD2. Does this perturbation cause a significant change in RSAD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1464
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and TRPM4 expression is quantified. Does this perturbation result in a significant change in TRPM4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and TRPM4 expression is quantified. Does this perturbation result in a significant change in TRPM4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3842
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and HAGH expression is observed. Does this perturbation lead to a significant difference in HAGH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and HAGH expression is observed. Does this perturbation lead to a significant difference in HAGH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2633
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in ARSA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in ARSA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":685
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and CTC-550B14.7 expression is measured. Determine whether CTC-550B14.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and CTC-550B14.7 expression is measured. Determine whether CTC-550B14.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4559
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in PPP1R16B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in PPP1R16B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":595
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of H3F3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of H3F3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2327
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and CELF6 expression is observed. Does this perturbation lead to a significant difference in CELF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and CELF6 expression is observed. Does this perturbation lead to a significant difference in CELF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5033
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in HIST1H2BC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in HIST1H2BC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4775
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and S100A10 expression is quantified. Does this perturbation result in a significant change in S100A10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and S100A10 expression is quantified. Does this perturbation result in a significant change in S100A10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4872
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in SDF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in SDF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1775
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and AC015987.1 expression is quantified. Does this perturbation result in a significant change in AC015987.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and AC015987.1 expression is quantified. Does this perturbation result in a significant change in AC015987.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2252
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of UHMK1. Does perturbing P4HB lead to a significant change in UHMK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of UHMK1. Does perturbing P4HB lead to a significant change in UHMK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4981
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and RP11-499F3.2 expression is quantified. Does this perturbation result in a significant change in RP11-499F3.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and RP11-499F3.2 expression is quantified. Does this perturbation result in a significant change in RP11-499F3.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2882
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of AC008074.3 is measured. Determine whether AC008074.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of AC008074.3 is measured. Determine whether AC008074.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1906
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of NBEAL2. Does this perturbation cause a significant change in NBEAL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of NBEAL2. Does this perturbation cause a significant change in NBEAL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and RP11-445H22.3 expression is measured. Determine whether RP11-445H22.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and RP11-445H22.3 expression is measured. Determine whether RP11-445H22.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3819
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor NFAT5 expression. Decide whether this perturbation leads to a significant alteration in NFAT5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor NFAT5 expression. Decide whether this perturbation leads to a significant alteration in NFAT5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1818
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and TRIM24 expression is observed. Does this perturbation lead to a significant difference in TRIM24 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and TRIM24 expression is observed. Does this perturbation lead to a significant difference in TRIM24 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3193
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and RSL24D1 expression is quantified. Does this perturbation result in a significant change in RSL24D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and RSL24D1 expression is quantified. Does this perturbation result in a significant change in RSL24D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":872
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of RPL39 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of RPL39 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1747
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of NBEAL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of NBEAL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor FOXO6 expression. Decide whether this perturbation leads to a significant alteration in FOXO6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor FOXO6 expression. Decide whether this perturbation leads to a significant alteration in FOXO6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4128
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of FOXO6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of FOXO6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4127
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in KIAA1586 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in KIAA1586 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4655
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of CTBS is measured. Determine whether CTBS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of CTBS is measured. Determine whether CTBS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4446
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and HRK expression is observed. Does this perturbation lead to a significant difference in HRK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and HRK expression is observed. Does this perturbation lead to a significant difference in HRK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1043
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of CD46 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of CD46 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4217
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of RP11-81A22.5 is measured. Does this perturbation cause a significant change in RP11-81A22.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of RP11-81A22.5 is measured. Does this perturbation cause a significant change in RP11-81A22.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1610
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in PHF3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in PHF3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and PTAR1 expression is quantified. Does this perturbation result in a significant change in PTAR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and PTAR1 expression is quantified. Does this perturbation result in a significant change in PTAR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2102
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in IL2RB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in IL2RB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4005
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of MORF4L2. Does this perturbation cause a significant change in MORF4L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of MORF4L2. Does this perturbation cause a significant change in MORF4L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2624
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of KCNQ1OT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of KCNQ1OT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4627
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and SMIM14 expression is quantified. Does this perturbation result in a significant change in SMIM14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and SMIM14 expression is quantified. Does this perturbation result in a significant change in SMIM14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3302
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of POU2F2. Does this perturbation cause a significant change in POU2F2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of POU2F2. Does this perturbation cause a significant change in POU2F2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":654
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and SPEN expression is observed. Does this perturbation lead to a significant difference in SPEN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and SPEN expression is observed. Does this perturbation lead to a significant difference in SPEN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1573
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of ZP3 is measured. Determine whether ZP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of ZP3 is measured. Determine whether ZP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2546
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of SLC26A1. Does this perturbation cause a significant change in SLC26A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of SLC26A1. Does this perturbation cause a significant change in SLC26A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2194
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of SKIL. Does perturbing ASCC3 lead to a significant change in SKIL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of SKIL. Does perturbing ASCC3 lead to a significant change in SKIL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2941
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of ANPEP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of ANPEP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4797
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and LPAR5 expression is observed. Does this perturbation lead to a significant difference in LPAR5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and LPAR5 expression is observed. Does this perturbation lead to a significant difference in LPAR5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of RDH10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of RDH10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":147
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and RP11-3D4.3 expression is observed. Does this perturbation lead to a significant difference in RP11-3D4.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and RP11-3D4.3 expression is observed. Does this perturbation lead to a significant difference in RP11-3D4.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3643
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of BAMBI is measured. Does this perturbation cause a significant change in BAMBI expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of BAMBI is measured. Does this perturbation cause a significant change in BAMBI expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1270
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor GRN expression. Decide whether this perturbation leads to a significant alteration in GRN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor GRN expression. Decide whether this perturbation leads to a significant alteration in GRN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4338
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor RGS20 expression. Decide whether this perturbation leads to a significant alteration in RGS20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor RGS20 expression. Decide whether this perturbation leads to a significant alteration in RGS20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3128
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of LINC01031. Does perturbing CHERP lead to a significant change in LINC01031 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of LINC01031. Does perturbing CHERP lead to a significant change in LINC01031 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4241
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and ZNF280B expression is measured. Determine whether ZNF280B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and ZNF280B expression is measured. Determine whether ZNF280B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1289
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in F2RL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in F2RL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2335
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of MT2A. Does this perturbation cause a significant change in MT2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of MT2A. Does this perturbation cause a significant change in MT2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3164
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of RP11-119J18.1. Does this perturbation cause a significant change in RP11-119J18.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of RP11-119J18.1. Does this perturbation cause a significant change in RP11-119J18.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2444
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of TOPBP1. Does this perturbation cause a significant change in TOPBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of TOPBP1. Does this perturbation cause a significant change in TOPBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3804
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and ESCO1 expression is observed. Does this perturbation lead to a significant difference in ESCO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and ESCO1 expression is observed. Does this perturbation lead to a significant difference in ESCO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":863
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and RP11-254F7.4 expression is observed. Does this perturbation lead to a significant difference in RP11-254F7.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and RP11-254F7.4 expression is observed. Does this perturbation lead to a significant difference in RP11-254F7.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2393
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of HMGCS1 is measured. Determine whether HMGCS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of HMGCS1 is measured. Determine whether HMGCS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":376
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of RCBTB2 is measured. Determine whether RCBTB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of RCBTB2 is measured. Determine whether RCBTB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1336
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of JARID2. Does this perturbation cause a significant change in JARID2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of JARID2. Does this perturbation cause a significant change in JARID2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1214
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and TOPBP1 expression is observed. Does this perturbation lead to a significant difference in TOPBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and TOPBP1 expression is observed. Does this perturbation lead to a significant difference in TOPBP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3803
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and HIST1H2AC expression is observed. Does this perturbation lead to a significant difference in HIST1H2AC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and HIST1H2AC expression is observed. Does this perturbation lead to a significant difference in HIST1H2AC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3023
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of TET1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of TET1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":137
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of RP11-119J18.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of RP11-119J18.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2447
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and RP11-423O2.5 expression is quantified. Does this perturbation result in a significant change in RP11-423O2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and RP11-423O2.5 expression is quantified. Does this perturbation result in a significant change in RP11-423O2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":302
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and SERPINH1 expression is observed. Does this perturbation lead to a significant difference in SERPINH1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and SERPINH1 expression is observed. Does this perturbation lead to a significant difference in SERPINH1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1643
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in GMEB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in GMEB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1205
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in NRIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in NRIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3625
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of C6orf120 is measured. Does this perturbation cause a significant change in C6orf120 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of C6orf120 is measured. Does this perturbation cause a significant change in C6orf120 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2260
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of ZEB1 is measured. Does this perturbation cause a significant change in ZEB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of ZEB1 is measured. Does this perturbation cause a significant change in ZEB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1380
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2535
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in DYNC1H1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in DYNC1H1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3145
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and CTD-2587M2.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2587M2.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and CTD-2587M2.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2587M2.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1913
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of NOXA1 is measured. Determine whether NOXA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of NOXA1 is measured. Determine whether NOXA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1416
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of LINC00938 is measured. Determine whether LINC00938 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of LINC00938 is measured. Determine whether LINC00938 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4106
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of HIST1H3D is measured. Does this perturbation cause a significant change in HIST1H3D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of HIST1H3D is measured. Does this perturbation cause a significant change in HIST1H3D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":910
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of PARP11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of PARP11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3707
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of RTN2. Does this perturbation cause a significant change in RTN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of RTN2. Does this perturbation cause a significant change in RTN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2064
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of CTD-2267D19.3 is measured. Determine whether CTD-2267D19.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of CTD-2267D19.3 is measured. Determine whether CTD-2267D19.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1546
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and SLC37A1 expression is measured. Determine whether SLC37A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and SLC37A1 expression is measured. Determine whether SLC37A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1159
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and RP1-274L7.1 expression is quantified. Does this perturbation result in a significant change in RP1-274L7.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and RP1-274L7.1 expression is quantified. Does this perturbation result in a significant change in RP1-274L7.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4072
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and ZEB2 expression is measured. Determine whether ZEB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and ZEB2 expression is measured. Determine whether ZEB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":969
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor SLC37A1 expression. Decide whether this perturbation leads to a significant alteration in SLC37A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor SLC37A1 expression. Decide whether this perturbation leads to a significant alteration in SLC37A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1158
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2305
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of ATP5EP2 is measured. Determine whether ATP5EP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of ATP5EP2 is measured. Determine whether ATP5EP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2956
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2736
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in SEPT5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in SEPT5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3545
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of REST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of REST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":797
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PIF1. Does this perturbation cause a significant change in PIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PIF1. Does this perturbation cause a significant change in PIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3074
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of RNF139-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of RNF139-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2527
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of RP11-247A12.2 is measured. Does this perturbation cause a significant change in RP11-247A12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of RP11-247A12.2 is measured. Does this perturbation cause a significant change in RP11-247A12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1660
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and CFH expression is measured. Determine whether CFH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and CFH expression is measured. Determine whether CFH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5059
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and MT2A expression is observed. Does this perturbation lead to a significant difference in MT2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and MT2A expression is observed. Does this perturbation lead to a significant difference in MT2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3163
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of RP11-81A22.5. Does perturbing PDIA6 lead to a significant change in RP11-81A22.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of RP11-81A22.5. Does perturbing PDIA6 lead to a significant change in RP11-81A22.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1611
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor CDKN2C expression. Decide whether this perturbation leads to a significant alteration in CDKN2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor CDKN2C expression. Decide whether this perturbation leads to a significant alteration in CDKN2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2818
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in ATF7IP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in ATF7IP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4525
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of CCRL2. Does perturbing SRP68 lead to a significant change in CCRL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of CCRL2. Does perturbing SRP68 lead to a significant change in CCRL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3551
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of GCKR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of GCKR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4307
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in GSN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in GSN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3205
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2723
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of CLDN11. Does perturbing SEC63 lead to a significant change in CLDN11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of CLDN11. Does perturbing SEC63 lead to a significant change in CLDN11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2611
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of NINJ2 is measured. Determine whether NINJ2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of NINJ2 is measured. Determine whether NINJ2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2146
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor RP11-573D15.9 expression. Decide whether this perturbation leads to a significant alteration in RP11-573D15.9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor RP11-573D15.9 expression. Decide whether this perturbation leads to a significant alteration in RP11-573D15.9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1298
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and APOL4 expression is quantified. Does this perturbation result in a significant change in APOL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and APOL4 expression is quantified. Does this perturbation result in a significant change in APOL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":892
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of GS1-166A23.1. Does this perturbation cause a significant change in GS1-166A23.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of GS1-166A23.1. Does this perturbation cause a significant change in GS1-166A23.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3294
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in C6orf120 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in C6orf120 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2265
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of CASP8. Does this perturbation cause a significant change in CASP8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of CASP8. Does this perturbation cause a significant change in CASP8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":224
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of TMEM60 is measured. Determine whether TMEM60 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of TMEM60 is measured. Determine whether TMEM60 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3516
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor TFPI expression. Decide whether this perturbation leads to a significant alteration in TFPI expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor TFPI expression. Decide whether this perturbation leads to a significant alteration in TFPI expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3918
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and DSC2 expression is measured. Determine whether DSC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and DSC2 expression is measured. Determine whether DSC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4099
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of RP11-146D12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of RP11-146D12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":477
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and P4HA2 expression is measured. Determine whether P4HA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and P4HA2 expression is measured. Determine whether P4HA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2409
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of NUF2. Does this perturbation cause a significant change in NUF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of NUF2. Does this perturbation cause a significant change in NUF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1394
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of TSC22D4 is measured. Does this perturbation cause a significant change in TSC22D4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of TSC22D4 is measured. Does this perturbation cause a significant change in TSC22D4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3270
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and MORF4L2 expression is measured. Determine whether MORF4L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and MORF4L2 expression is measured. Determine whether MORF4L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2629
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of CTD-2020K17.1. Does this perturbation cause a significant change in CTD-2020K17.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of CTD-2020K17.1. Does this perturbation cause a significant change in CTD-2020K17.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4194
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of OXLD1. Does perturbing SEC61B lead to a significant change in OXLD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of OXLD1. Does perturbing SEC61B lead to a significant change in OXLD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2851
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of FCGRT. Does perturbing SCYL1 lead to a significant change in FCGRT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of FCGRT. Does perturbing SCYL1 lead to a significant change in FCGRT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3531
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor OBSCN expression. Decide whether this perturbation leads to a significant alteration in OBSCN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor OBSCN expression. Decide whether this perturbation leads to a significant alteration in OBSCN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3828
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in NRIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in NRIP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":125
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor TNFRSF10B expression. Decide whether this perturbation leads to a significant alteration in TNFRSF10B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor TNFRSF10B expression. Decide whether this perturbation leads to a significant alteration in TNFRSF10B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2288
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and LBX1 expression is quantified. Does this perturbation result in a significant change in LBX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and LBX1 expression is quantified. Does this perturbation result in a significant change in LBX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1592
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and NOSTRIN expression is observed. Does this perturbation lead to a significant difference in NOSTRIN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and NOSTRIN expression is observed. Does this perturbation lead to a significant difference in NOSTRIN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4323
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and P4HA2 expression is quantified. Does this perturbation result in a significant change in P4HA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and P4HA2 expression is quantified. Does this perturbation result in a significant change in P4HA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2402
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and NBEAL2 expression is observed. Does this perturbation lead to a significant difference in NBEAL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and NBEAL2 expression is observed. Does this perturbation lead to a significant difference in NBEAL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ZFP36L2 expression. Decide whether this perturbation leads to a significant alteration in ZFP36L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ZFP36L2 expression. Decide whether this perturbation leads to a significant alteration in ZFP36L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3458
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and THBS1 expression is measured. Determine whether THBS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and THBS1 expression is measured. Determine whether THBS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5019
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RP11-65L19.4. Does this perturbation cause a significant change in RP11-65L19.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RP11-65L19.4. Does this perturbation cause a significant change in RP11-65L19.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of CASP4 is measured. Does this perturbation cause a significant change in CASP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of CASP4 is measured. Does this perturbation cause a significant change in CASP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of PDE9A is measured. Does this perturbation cause a significant change in PDE9A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of PDE9A is measured. Does this perturbation cause a significant change in PDE9A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":190
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and CST7 expression is measured. Determine whether CST7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and CST7 expression is measured. Determine whether CST7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2209
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of AC015987.1 is measured. Does this perturbation cause a significant change in AC015987.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of AC015987.1 is measured. Does this perturbation cause a significant change in AC015987.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2250
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor SERPINH1 expression. Decide whether this perturbation leads to a significant alteration in SERPINH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor SERPINH1 expression. Decide whether this perturbation leads to a significant alteration in SERPINH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1648
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of EPB42 is measured. Does this perturbation cause a significant change in EPB42 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of EPB42 is measured. Does this perturbation cause a significant change in EPB42 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1710
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and P4HA2 expression is observed. Does this perturbation lead to a significant difference in P4HA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and P4HA2 expression is observed. Does this perturbation lead to a significant difference in P4HA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of NTRK1 is measured. Does this perturbation cause a significant change in NTRK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of NTRK1 is measured. Does this perturbation cause a significant change in NTRK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4030
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and RP11-119J18.1 expression is quantified. Does this perturbation result in a significant change in RP11-119J18.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and RP11-119J18.1 expression is quantified. Does this perturbation result in a significant change in RP11-119J18.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2442
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in ACE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in ACE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2575
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and SERPINF2 expression is quantified. Does this perturbation result in a significant change in SERPINF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and SERPINF2 expression is quantified. Does this perturbation result in a significant change in SERPINF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3952
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and ANXA4 expression is measured. Determine whether ANXA4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and ANXA4 expression is measured. Determine whether ANXA4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":749
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor EIF4B expression. Decide whether this perturbation leads to a significant alteration in EIF4B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor EIF4B expression. Decide whether this perturbation leads to a significant alteration in EIF4B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4968
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of TLK2 is measured. Determine whether TLK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of TLK2 is measured. Determine whether TLK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4766
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of SLBP is measured. Determine whether SLBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of SLBP is measured. Determine whether SLBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2136
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of RP1-274L7.1 is measured. Determine whether RP1-274L7.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of RP1-274L7.1 is measured. Determine whether RP1-274L7.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4076
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and PDE9A expression is quantified. Does this perturbation result in a significant change in PDE9A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and PDE9A expression is quantified. Does this perturbation result in a significant change in PDE9A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":192
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of SLFNL1. Does this perturbation cause a significant change in SLFNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of SLFNL1. Does this perturbation cause a significant change in SLFNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":454
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of IL18R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of IL18R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4207
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor RP11-363D14.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-363D14.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor RP11-363D14.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-363D14.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3058
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in PAXBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in PAXBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4745
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of KCTD19 is measured. Determine whether KCTD19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of KCTD19 is measured. Determine whether KCTD19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2686
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and SPEN expression is measured. Determine whether SPEN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and SPEN expression is measured. Determine whether SPEN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4089
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of PIK3R1 is measured. Does this perturbation cause a significant change in PIK3R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of PIK3R1 is measured. Does this perturbation cause a significant change in PIK3R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5100
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of NPDC1. Does this perturbation cause a significant change in NPDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of NPDC1. Does this perturbation cause a significant change in NPDC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1324
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of IL2RB. Does perturbing TMED10 lead to a significant change in IL2RB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of IL2RB. Does perturbing TMED10 lead to a significant change in IL2RB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4001
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and CTBS expression is quantified. Does this perturbation result in a significant change in CTBS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and CTBS expression is quantified. Does this perturbation result in a significant change in CTBS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4442
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in LINC00862 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in LINC00862 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4595
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and RP11-573D15.9 expression is observed. Does this perturbation lead to a significant difference in RP11-573D15.9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and RP11-573D15.9 expression is observed. Does this perturbation lead to a significant difference in RP11-573D15.9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1293
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of TSPAN33. Does perturbing SCYL1 lead to a significant change in TSPAN33 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of TSPAN33. Does perturbing SCYL1 lead to a significant change in TSPAN33 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3521
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in HIST1H1D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in HIST1H1D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4345
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of RP11-322J23.1. Does this perturbation cause a significant change in RP11-322J23.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of RP11-322J23.1. Does this perturbation cause a significant change in RP11-322J23.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4724
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of AKAP11 is measured. Determine whether AKAP11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of AKAP11 is measured. Determine whether AKAP11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1926
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in GATA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in GATA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5115
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor DNMBP expression. Decide whether this perturbation leads to a significant alteration in DNMBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor DNMBP expression. Decide whether this perturbation leads to a significant alteration in DNMBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4018
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and SDF4 expression is measured. Determine whether SDF4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and SDF4 expression is measured. Determine whether SDF4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1779
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of CLDN11. Does this perturbation cause a significant change in CLDN11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of CLDN11. Does this perturbation cause a significant change in CLDN11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2614
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of TMEM60 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of TMEM60 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3517
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and DSC2 expression is quantified. Does this perturbation result in a significant change in DSC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and DSC2 expression is quantified. Does this perturbation result in a significant change in DSC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4092
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of MED13 is measured. Determine whether MED13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of MED13 is measured. Determine whether MED13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4316
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor TRIM24 expression. Decide whether this perturbation leads to a significant alteration in TRIM24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor TRIM24 expression. Decide whether this perturbation leads to a significant alteration in TRIM24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3198
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of NAV1 is measured. Does this perturbation cause a significant change in NAV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of NAV1 is measured. Does this perturbation cause a significant change in NAV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4460
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of SPEN. Does perturbing PDIA6 lead to a significant change in SPEN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of SPEN. Does perturbing PDIA6 lead to a significant change in SPEN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1571
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of CCRL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of CCRL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3557
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and SPAST expression is observed. Does this perturbation lead to a significant difference in SPAST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and SPAST expression is observed. Does this perturbation lead to a significant difference in SPAST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2843
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor GCKR expression. Decide whether this perturbation leads to a significant alteration in GCKR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor GCKR expression. Decide whether this perturbation leads to a significant alteration in GCKR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4308
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and NTRK1 expression is measured. Determine whether NTRK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and NTRK1 expression is measured. Determine whether NTRK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4039
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of COPB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of COPB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":807
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of EP300. Does perturbing TTI2 lead to a significant change in EP300 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of EP300. Does perturbing TTI2 lead to a significant change in EP300 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2051
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in NPAT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in NPAT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3325
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and CTD-2020K17.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2020K17.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and CTD-2020K17.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2020K17.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4193
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor AC079466.1 expression. Decide whether this perturbation leads to a significant alteration in AC079466.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor AC079466.1 expression. Decide whether this perturbation leads to a significant alteration in AC079466.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1448
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of SLBP. Does this perturbation cause a significant change in SLBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of SLBP. Does this perturbation cause a significant change in SLBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2134
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3965
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RAI14. Does this perturbation cause a significant change in RAI14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RAI14. Does this perturbation cause a significant change in RAI14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2704
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of NFE2L3 is measured. Determine whether NFE2L3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of NFE2L3 is measured. Determine whether NFE2L3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1586
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of DOCK11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of DOCK11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":367
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor NFE2L3 expression. Decide whether this perturbation leads to a significant alteration in NFE2L3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor NFE2L3 expression. Decide whether this perturbation leads to a significant alteration in NFE2L3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1588
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and QSER1 expression is observed. Does this perturbation lead to a significant difference in QSER1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and QSER1 expression is observed. Does this perturbation lead to a significant difference in QSER1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4683
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and APOBEC3D expression is observed. Does this perturbation lead to a significant difference in APOBEC3D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and APOBEC3D expression is observed. Does this perturbation lead to a significant difference in APOBEC3D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3573
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in CTCFL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in CTCFL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2605
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and STARD9 expression is quantified. Does this perturbation result in a significant change in STARD9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and STARD9 expression is quantified. Does this perturbation result in a significant change in STARD9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4602
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in TSPAN33 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in TSPAN33 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3525
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in TRPM4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in TRPM4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3845
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor TRIM38 expression. Decide whether this perturbation leads to a significant alteration in TRIM38 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor TRIM38 expression. Decide whether this perturbation leads to a significant alteration in TRIM38 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3388
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and C12orf44 expression is quantified. Does this perturbation result in a significant change in C12orf44 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and C12orf44 expression is quantified. Does this perturbation result in a significant change in C12orf44 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1532
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor CHD3 expression. Decide whether this perturbation leads to a significant alteration in CHD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor CHD3 expression. Decide whether this perturbation leads to a significant alteration in CHD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4908
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of TET1. Does this perturbation cause a significant change in TET1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of TET1. Does this perturbation cause a significant change in TET1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":134
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in LIMS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in LIMS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3375
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in GNPTG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in GNPTG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3095
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in RP13-216E22.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in RP13-216E22.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2435
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and PKDCC expression is measured. Determine whether PKDCC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and PKDCC expression is measured. Determine whether PKDCC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1799
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in REST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in REST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":795
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PIF1 expression is observed. Does this perturbation lead to a significant difference in PIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PIF1 expression is observed. Does this perturbation lead to a significant difference in PIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3073
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and SPCS2 expression is observed. Does this perturbation lead to a significant difference in SPCS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and SPCS2 expression is observed. Does this perturbation lead to a significant difference in SPCS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":693
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of TACC3 is measured. Does this perturbation cause a significant change in TACC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of TACC3 is measured. Does this perturbation cause a significant change in TACC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1860
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of PDRG1 is measured. Determine whether PDRG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of PDRG1 is measured. Determine whether PDRG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4156
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of RNF139-AS1. Does perturbing FARSB lead to a significant change in RNF139-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of RNF139-AS1. Does perturbing FARSB lead to a significant change in RNF139-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2521
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and ACSM3 expression is quantified. Does this perturbation result in a significant change in ACSM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and ACSM3 expression is quantified. Does this perturbation result in a significant change in ACSM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2212
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in KHDC1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in KHDC1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1065
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and ARSA expression is quantified. Does this perturbation result in a significant change in ARSA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and ARSA expression is quantified. Does this perturbation result in a significant change in ARSA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":682
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of ARHGAP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of ARHGAP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1757
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of CDKN2C. Does this perturbation cause a significant change in CDKN2C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of CDKN2C. Does this perturbation cause a significant change in CDKN2C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2814
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in HRK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in HRK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1045
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and RP11-381O7.3 expression is observed. Does this perturbation lead to a significant difference in RP11-381O7.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and RP11-381O7.3 expression is observed. Does this perturbation lead to a significant difference in RP11-381O7.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1553
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor DDX3X expression. Decide whether this perturbation leads to a significant alteration in DDX3X expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor DDX3X expression. Decide whether this perturbation leads to a significant alteration in DDX3X expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1088
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of WARS is measured. Determine whether WARS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of WARS is measured. Determine whether WARS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4886
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and TOB2 expression is quantified. Does this perturbation result in a significant change in TOB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and TOB2 expression is quantified. Does this perturbation result in a significant change in TOB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":982
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RGS20 expression. Decide whether this perturbation leads to a significant alteration in RGS20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor RGS20 expression. Decide whether this perturbation leads to a significant alteration in RGS20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2718
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and TTC18 expression is observed. Does this perturbation lead to a significant difference in TTC18 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and TTC18 expression is observed. Does this perturbation lead to a significant difference in TTC18 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3693
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and KLF6 expression is quantified. Does this perturbation result in a significant change in KLF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and KLF6 expression is quantified. Does this perturbation result in a significant change in KLF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2292
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of NSD1 is measured. Determine whether NSD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of NSD1 is measured. Determine whether NSD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1346
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ROBO1 expression is measured. Determine whether ROBO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ROBO1 expression is measured. Determine whether ROBO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3949
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in AFF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in AFF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2915
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of TTC18 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of TTC18 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3697
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of CENPC. Does this perturbation cause a significant change in CENPC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of CENPC. Does this perturbation cause a significant change in CENPC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2184
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and DDX3X expression is measured. Determine whether DDX3X exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and DDX3X expression is measured. Determine whether DDX3X exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1089
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in THBS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in THBS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5015
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of CD46 is measured. Determine whether CD46 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of CD46 is measured. Determine whether CD46 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4216
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in SPAST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in SPAST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":925
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and NUFIP2 expression is quantified. Does this perturbation result in a significant change in NUFIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and NUFIP2 expression is quantified. Does this perturbation result in a significant change in NUFIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2462
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of NOSTRIN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of NOSTRIN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4327
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and RDH10 expression is quantified. Does this perturbation result in a significant change in RDH10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and RDH10 expression is quantified. Does this perturbation result in a significant change in RDH10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":142
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of C12orf23. Does perturbing MTHFD1 lead to a significant change in C12orf23 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of C12orf23. Does perturbing MTHFD1 lead to a significant change in C12orf23 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1761
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and FYTTD1 expression is observed. Does this perturbation lead to a significant difference in FYTTD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and FYTTD1 expression is observed. Does this perturbation lead to a significant difference in FYTTD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2363
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and S100A10 expression is observed. Does this perturbation lead to a significant difference in S100A10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and S100A10 expression is observed. Does this perturbation lead to a significant difference in S100A10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4873
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and AC018878.3 expression is observed. Does this perturbation lead to a significant difference in AC018878.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and AC018878.3 expression is observed. Does this perturbation lead to a significant difference in AC018878.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3283
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor RP11-254F7.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-254F7.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor RP11-254F7.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-254F7.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2398
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of ZC3H7A. Does this perturbation cause a significant change in ZC3H7A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of ZC3H7A. Does this perturbation cause a significant change in ZC3H7A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3674
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of USP37. Does this perturbation cause a significant change in USP37 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of USP37. Does this perturbation cause a significant change in USP37 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1734
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and EXOC3L2 expression is quantified. Does this perturbation result in a significant change in EXOC3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and EXOC3L2 expression is quantified. Does this perturbation result in a significant change in EXOC3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3352
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and ABI2 expression is quantified. Does this perturbation result in a significant change in ABI2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and ABI2 expression is quantified. Does this perturbation result in a significant change in ABI2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2022
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and TOPBP1 expression is measured. Determine whether TOPBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and TOPBP1 expression is measured. Determine whether TOPBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3809
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor TOB2 expression. Decide whether this perturbation leads to a significant alteration in TOB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor TOB2 expression. Decide whether this perturbation leads to a significant alteration in TOB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":988
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of DSC2. Does this perturbation cause a significant change in DSC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of DSC2. Does this perturbation cause a significant change in DSC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4094
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and PHF3 expression is observed. Does this perturbation lead to a significant difference in PHF3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and PHF3 expression is observed. Does this perturbation lead to a significant difference in PHF3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of RP11-381O7.3 is measured. Determine whether RP11-381O7.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of RP11-381O7.3 is measured. Determine whether RP11-381O7.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1556
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of RP11-499F3.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of RP11-499F3.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2887
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of S100A11. Does perturbing EIF2B3 lead to a significant change in S100A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of S100A11. Does perturbing EIF2B3 lead to a significant change in S100A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4641
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of ATF6 is measured. Determine whether ATF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of ATF6 is measured. Determine whether ATF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":856
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in SNHG7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in SNHG7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4045
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of NRIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of NRIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":127
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of F2RL2 is measured. Does this perturbation cause a significant change in F2RL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of F2RL2 is measured. Does this perturbation cause a significant change in F2RL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2330
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of LRRC4B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of LRRC4B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2177
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and RP11-3D4.3 expression is measured. Determine whether RP11-3D4.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and RP11-3D4.3 expression is measured. Determine whether RP11-3D4.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3649
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in RP11-61E11.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in RP11-61E11.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1425
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of OBSCN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of OBSCN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3827
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and DDX3X expression is quantified. Does this perturbation result in a significant change in DDX3X expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and DDX3X expression is quantified. Does this perturbation result in a significant change in DDX3X expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1082
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of KIAA1586. Does this perturbation cause a significant change in KIAA1586 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of KIAA1586. Does this perturbation cause a significant change in KIAA1586 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4654
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of SLC37A1 is measured. Does this perturbation cause a significant change in SLC37A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of SLC37A1 is measured. Does this perturbation cause a significant change in SLC37A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1150
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and IL8 expression is observed. Does this perturbation lead to a significant difference in IL8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and IL8 expression is observed. Does this perturbation lead to a significant difference in IL8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1253
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of UHMK1 is measured. Determine whether UHMK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of UHMK1 is measured. Determine whether UHMK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4986
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and LIMS1 expression is measured. Determine whether LIMS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and LIMS1 expression is measured. Determine whether LIMS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3379
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of FGF11. Does this perturbation cause a significant change in FGF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of FGF11. Does this perturbation cause a significant change in FGF11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4174
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of NFAT5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of NFAT5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1817
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of ATXN7L3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of ATXN7L3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4937
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and LINC00862 expression is measured. Determine whether LINC00862 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and LINC00862 expression is measured. Determine whether LINC00862 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4599
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and BRWD3 expression is measured. Determine whether BRWD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and BRWD3 expression is measured. Determine whether BRWD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":739
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and SDF4 expression is observed. Does this perturbation lead to a significant difference in SDF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and SDF4 expression is observed. Does this perturbation lead to a significant difference in SDF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1773
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in KDM1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in KDM1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1165
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor ABI2 expression. Decide whether this perturbation leads to a significant alteration in ABI2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor ABI2 expression. Decide whether this perturbation leads to a significant alteration in ABI2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2028
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of UHRF1BP1L is measured. Does this perturbation cause a significant change in UHRF1BP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of UHRF1BP1L is measured. Does this perturbation cause a significant change in UHRF1BP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":240
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RP11-685N10.1 expression is quantified. Does this perturbation result in a significant change in RP11-685N10.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RP11-685N10.1 expression is quantified. Does this perturbation result in a significant change in RP11-685N10.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2752
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and JUND expression is quantified. Does this perturbation result in a significant change in JUND expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and JUND expression is quantified. Does this perturbation result in a significant change in JUND expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":772
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of ANKLE2 is measured. Determine whether ANKLE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of ANKLE2 is measured. Determine whether ANKLE2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2316
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of UFD1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of UFD1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2507
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of HIST1H1E. Does perturbing IARS2 lead to a significant change in HIST1H1E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of HIST1H1E. Does perturbing IARS2 lead to a significant change in HIST1H1E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1021
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of IL8 is measured. Does this perturbation cause a significant change in IL8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of IL8 is measured. Does this perturbation cause a significant change in IL8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1250
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of SPCS2. Does perturbing SLMO2 lead to a significant change in SPCS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of SPCS2. Does perturbing SLMO2 lead to a significant change in SPCS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":691
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of RP11-666A20.4. Does perturbing CHERP lead to a significant change in RP11-666A20.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of RP11-666A20.4. Does perturbing CHERP lead to a significant change in RP11-666A20.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4231
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor SDF4 expression. Decide whether this perturbation leads to a significant alteration in SDF4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor SDF4 expression. Decide whether this perturbation leads to a significant alteration in SDF4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1778
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in MEX3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in MEX3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":675
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor RP11-304M2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-304M2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor RP11-304M2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-304M2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4538
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of NOSTRIN is measured. Determine whether NOSTRIN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of NOSTRIN is measured. Determine whether NOSTRIN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4326
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and EIF4B expression is observed. Does this perturbation lead to a significant difference in EIF4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and EIF4B expression is observed. Does this perturbation lead to a significant difference in EIF4B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4963
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of PDE4D. Does perturbing IER3IP1 lead to a significant change in PDE4D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of PDE4D. Does perturbing IER3IP1 lead to a significant change in PDE4D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":511
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of CLDN11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of CLDN11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4547
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of SHOX2 is measured. Does this perturbation cause a significant change in SHOX2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of SHOX2 is measured. Does this perturbation cause a significant change in SHOX2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":990
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and CTD-2587M2.1 expression is quantified. Does this perturbation result in a significant change in CTD-2587M2.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and CTD-2587M2.1 expression is quantified. Does this perturbation result in a significant change in CTD-2587M2.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1912
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of PITPNB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of PITPNB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3737
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and KCNQ1OT1 expression is quantified. Does this perturbation result in a significant change in KCNQ1OT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and KCNQ1OT1 expression is quantified. Does this perturbation result in a significant change in KCNQ1OT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4622
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of IRF7 is measured. Does this perturbation cause a significant change in IRF7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of IRF7 is measured. Does this perturbation cause a significant change in IRF7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":530
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of SLC25A35. Does perturbing ARHGAP22 lead to a significant change in SLC25A35 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of SLC25A35. Does perturbing ARHGAP22 lead to a significant change in SLC25A35 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3151
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of KCTD1 is measured. Determine whether KCTD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of KCTD1 is measured. Determine whether KCTD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1376
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and SERPING1 expression is measured. Determine whether SERPING1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and SERPING1 expression is measured. Determine whether SERPING1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3249
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and RNF139-AS1 expression is quantified. Does this perturbation result in a significant change in RNF139-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and RNF139-AS1 expression is quantified. Does this perturbation result in a significant change in RNF139-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2522
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of EXO1 is measured. Determine whether EXO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of EXO1 is measured. Determine whether EXO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2836
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of AC104532.4. Does perturbing ASCC3 lead to a significant change in AC104532.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of AC104532.4. Does perturbing ASCC3 lead to a significant change in AC104532.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2981
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and GMEB1 expression is measured. Determine whether GMEB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and GMEB1 expression is measured. Determine whether GMEB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1209
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and HP1BP3 expression is quantified. Does this perturbation result in a significant change in HP1BP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and HP1BP3 expression is quantified. Does this perturbation result in a significant change in HP1BP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":612
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of IL2RB is measured. Determine whether IL2RB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of IL2RB is measured. Determine whether IL2RB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4006
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and ZNF429 expression is quantified. Does this perturbation result in a significant change in ZNF429 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and ZNF429 expression is quantified. Does this perturbation result in a significant change in ZNF429 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in SPEN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in SPEN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4085
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and CFH expression is observed. Does this perturbation lead to a significant difference in CFH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and CFH expression is observed. Does this perturbation lead to a significant difference in CFH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5053
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of TRPM4. Does perturbing DDOST lead to a significant change in TRPM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of TRPM4. Does perturbing DDOST lead to a significant change in TRPM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3841
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of AP000688.8 is measured. Does this perturbation cause a significant change in AP000688.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of AP000688.8 is measured. Does this perturbation cause a significant change in AP000688.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3330
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of CHST12 is measured. Determine whether CHST12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of CHST12 is measured. Determine whether CHST12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3466
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of SOBP. Does this perturbation cause a significant change in SOBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of SOBP. Does this perturbation cause a significant change in SOBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3634
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of RPL39 is measured. Determine whether RPL39 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of RPL39 is measured. Determine whether RPL39 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1746
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of VIM-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of VIM-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":487
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of DUSP21 is measured. Determine whether DUSP21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of DUSP21 is measured. Determine whether DUSP21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2746
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of AC007038.7. Does perturbing TARS lead to a significant change in AC007038.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of AC007038.7. Does perturbing TARS lead to a significant change in AC007038.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2921
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and AC012594.1 expression is measured. Determine whether AC012594.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and AC012594.1 expression is measured. Determine whether AC012594.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1679
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in MTPN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in MTPN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4735
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor ARSA expression. Decide whether this perturbation leads to a significant alteration in ARSA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor ARSA expression. Decide whether this perturbation leads to a significant alteration in ARSA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":688
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor UHMK1 expression. Decide whether this perturbation leads to a significant alteration in UHMK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor UHMK1 expression. Decide whether this perturbation leads to a significant alteration in UHMK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4988
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of ATAD2B. Does perturbing FECH lead to a significant change in ATAD2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of ATAD2B. Does perturbing FECH lead to a significant change in ATAD2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4391
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and JARID2 expression is measured. Determine whether JARID2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and JARID2 expression is measured. Determine whether JARID2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1219
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor STARD9 expression. Decide whether this perturbation leads to a significant alteration in STARD9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor STARD9 expression. Decide whether this perturbation leads to a significant alteration in STARD9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4608
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of TSC22D4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of TSC22D4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3277
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor PCK2 expression. Decide whether this perturbation leads to a significant alteration in PCK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor PCK2 expression. Decide whether this perturbation leads to a significant alteration in PCK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":338
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of PDE4D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of PDE4D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":517
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of ATP11B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of ATP11B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":297
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of ABI2 is measured. Does this perturbation cause a significant change in ABI2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of ABI2 is measured. Does this perturbation cause a significant change in ABI2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2020
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of EGLN3. Does this perturbation cause a significant change in EGLN3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of EGLN3. Does this perturbation cause a significant change in EGLN3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3314
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of HM13 is measured. Determine whether HM13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of HM13 is measured. Determine whether HM13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4516
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of DOCK8. Does this perturbation cause a significant change in DOCK8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of DOCK8. Does this perturbation cause a significant change in DOCK8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1564
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PIF1 expression is quantified. Does this perturbation result in a significant change in PIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PIF1 expression is quantified. Does this perturbation result in a significant change in PIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3072
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1133
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of LBX1. Does perturbing PDIA6 lead to a significant change in LBX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of LBX1. Does perturbing PDIA6 lead to a significant change in LBX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1591
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of PPM1N. Does perturbing SLC35B1 lead to a significant change in PPM1N expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of PPM1N. Does perturbing SLC35B1 lead to a significant change in PPM1N expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3921
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of CEBPG. Does this perturbation cause a significant change in CEBPG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of CEBPG. Does this perturbation cause a significant change in CEBPG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor HIST1H2AM expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor HIST1H2AM expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2428
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in ATP11B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in ATP11B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":295
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2046
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in DOCK11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in DOCK11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":365
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of CENPC is measured. Does this perturbation cause a significant change in CENPC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of CENPC is measured. Does this perturbation cause a significant change in CENPC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2180
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of PARP11. Does this perturbation cause a significant change in PARP11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of PARP11. Does this perturbation cause a significant change in PARP11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3704
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of AC007038.7 is measured. Determine whether AC007038.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of AC007038.7 is measured. Determine whether AC007038.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2926
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of ANPEP. Does perturbing DNAJC19 lead to a significant change in ANPEP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of ANPEP. Does perturbing DNAJC19 lead to a significant change in ANPEP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4791
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of RP11-434H6.6. Does this perturbation cause a significant change in RP11-434H6.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of RP11-434H6.6. Does this perturbation cause a significant change in RP11-434H6.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1894
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of CRNDE is measured. Determine whether CRNDE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of CRNDE is measured. Determine whether CRNDE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1976
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of RCBTB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of RCBTB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1337
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of SBF2 is measured. Determine whether SBF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of SBF2 is measured. Determine whether SBF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2566
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of NFE2 is measured. Does this perturbation cause a significant change in NFE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of NFE2 is measured. Does this perturbation cause a significant change in NFE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":210
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of WDR3. Does perturbing COPZ1 lead to a significant change in WDR3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of WDR3. Does perturbing COPZ1 lead to a significant change in WDR3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4561
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and KIF4A expression is quantified. Does this perturbation result in a significant change in KIF4A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and KIF4A expression is quantified. Does this perturbation result in a significant change in KIF4A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2582
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of DDX6 is measured. Does this perturbation cause a significant change in DDX6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of DDX6 is measured. Does this perturbation cause a significant change in DDX6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":520
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of KCNE3 is measured. Does this perturbation cause a significant change in KCNE3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of KCNE3 is measured. Does this perturbation cause a significant change in KCNE3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1010
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of ANXA4. Does this perturbation cause a significant change in ANXA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of ANXA4. Does this perturbation cause a significant change in ANXA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":744
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of ASPM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of ASPM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2667
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and CTC-308K20.1 expression is measured. Determine whether CTC-308K20.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and CTC-308K20.1 expression is measured. Determine whether CTC-308K20.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5139
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of TLK2. Does perturbing DNAJC19 lead to a significant change in TLK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of TLK2. Does perturbing DNAJC19 lead to a significant change in TLK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4761
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of FOXO6. Does this perturbation cause a significant change in FOXO6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of FOXO6. Does this perturbation cause a significant change in FOXO6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4124
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and RP11-666A20.4 expression is observed. Does this perturbation lead to a significant difference in RP11-666A20.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and RP11-666A20.4 expression is observed. Does this perturbation lead to a significant difference in RP11-666A20.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4233
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of RGS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of RGS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2877
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and PCF11 expression is observed. Does this perturbation lead to a significant difference in PCF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and PCF11 expression is observed. Does this perturbation lead to a significant difference in PCF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":543
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of ANKLE2. Does this perturbation cause a significant change in ANKLE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of ANKLE2. Does this perturbation cause a significant change in ANKLE2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2314
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor GDF11 expression. Decide whether this perturbation leads to a significant alteration in GDF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor GDF11 expression. Decide whether this perturbation leads to a significant alteration in GDF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":398
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of RP11-254F7.4. Does perturbing HSPA9 lead to a significant change in RP11-254F7.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of RP11-254F7.4. Does perturbing HSPA9 lead to a significant change in RP11-254F7.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2391
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and HERC2 expression is observed. Does this perturbation lead to a significant difference in HERC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and HERC2 expression is observed. Does this perturbation lead to a significant difference in HERC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":953
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of QSER1 is measured. Determine whether QSER1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of QSER1 is measured. Determine whether QSER1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4686
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of ATP2A3 is measured. Does this perturbation cause a significant change in ATP2A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of ATP2A3 is measured. Does this perturbation cause a significant change in ATP2A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1830
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ARHGAP6 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ARHGAP6 expression. Decide whether this perturbation leads to a significant alteration in ARHGAP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3428
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of ZNF280B is measured. Determine whether ZNF280B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of ZNF280B is measured. Determine whether ZNF280B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1106
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and COPB1 expression is observed. Does this perturbation lead to a significant difference in COPB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and COPB1 expression is observed. Does this perturbation lead to a significant difference in COPB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":803
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor F2RL2 expression. Decide whether this perturbation leads to a significant alteration in F2RL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor F2RL2 expression. Decide whether this perturbation leads to a significant alteration in F2RL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2338
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in EIF3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in EIF3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4805
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor MARCH8 expression. Decide whether this perturbation leads to a significant alteration in MARCH8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor MARCH8 expression. Decide whether this perturbation leads to a significant alteration in MARCH8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1438
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and CLDN11 expression is quantified. Does this perturbation result in a significant change in CLDN11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and CLDN11 expression is quantified. Does this perturbation result in a significant change in CLDN11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4542
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of TMEM60 is measured. Determine whether TMEM60 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of TMEM60 is measured. Determine whether TMEM60 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4976
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and BIRC5 expression is observed. Does this perturbation lead to a significant difference in BIRC5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and BIRC5 expression is observed. Does this perturbation lead to a significant difference in BIRC5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4503
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor DUT expression. Decide whether this perturbation leads to a significant alteration in DUT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor DUT expression. Decide whether this perturbation leads to a significant alteration in DUT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":278
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and RILPL2 expression is quantified. Does this perturbation result in a significant change in RILPL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and RILPL2 expression is quantified. Does this perturbation result in a significant change in RILPL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2802
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and SP100 expression is observed. Does this perturbation lead to a significant difference in SP100 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and SP100 expression is observed. Does this perturbation lead to a significant difference in SP100 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1143
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and SMIM14 expression is measured. Determine whether SMIM14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and SMIM14 expression is measured. Determine whether SMIM14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3309
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of PDE9A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of PDE9A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":197
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor PIK3IP1 expression. Decide whether this perturbation leads to a significant alteration in PIK3IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor PIK3IP1 expression. Decide whether this perturbation leads to a significant alteration in PIK3IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2868
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and RP11-328J2.1 expression is measured. Determine whether RP11-328J2.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and RP11-328J2.1 expression is measured. Determine whether RP11-328J2.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1099
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and RP11-157D23.2 expression is measured. Determine whether RP11-157D23.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and RP11-157D23.2 expression is measured. Determine whether RP11-157D23.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4429
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of SPAST is measured. Determine whether SPAST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of SPAST is measured. Determine whether SPAST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2846
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and NAV2 expression is quantified. Does this perturbation result in a significant change in NAV2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and NAV2 expression is quantified. Does this perturbation result in a significant change in NAV2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4862
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and AKAP11 expression is quantified. Does this perturbation result in a significant change in AKAP11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and AKAP11 expression is quantified. Does this perturbation result in a significant change in AKAP11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1922
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in ATP6V1B2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in ATP6V1B2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1605
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of SEPT5. Does perturbing SRP68 lead to a significant change in SEPT5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of SEPT5. Does perturbing SRP68 lead to a significant change in SEPT5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3541
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and HIST1H1D expression is observed. Does this perturbation lead to a significant difference in HIST1H1D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and HIST1H1D expression is observed. Does this perturbation lead to a significant difference in HIST1H1D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4343
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor LIMS1 expression. Decide whether this perturbation leads to a significant alteration in LIMS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor LIMS1 expression. Decide whether this perturbation leads to a significant alteration in LIMS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3378
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and RP11-838N2.4 expression is observed. Does this perturbation lead to a significant difference in RP11-838N2.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and RP11-838N2.4 expression is observed. Does this perturbation lead to a significant difference in RP11-838N2.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3033
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of HIST1H2AC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of HIST1H2AC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3027
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in VIM-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in VIM-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":485
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in SNRNP25 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in SNRNP25 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2155
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2729
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and CENPC expression is measured. Determine whether CENPC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and CENPC expression is measured. Determine whether CENPC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2189
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of CFH. Does perturbing SPCS3 lead to a significant change in CFH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of CFH. Does perturbing SPCS3 lead to a significant change in CFH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5051
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and RP11-435O5.4 expression is measured. Determine whether RP11-435O5.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and RP11-435O5.4 expression is measured. Determine whether RP11-435O5.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1199
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of P4HA2. Does perturbing CREB1 lead to a significant change in P4HA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of P4HA2. Does perturbing CREB1 lead to a significant change in P4HA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and BOLA3 expression is quantified. Does this perturbation result in a significant change in BOLA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and BOLA3 expression is quantified. Does this perturbation result in a significant change in BOLA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4632
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and UFD1L expression is quantified. Does this perturbation result in a significant change in UFD1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and UFD1L expression is quantified. Does this perturbation result in a significant change in UFD1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2502
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor AC005540.3 expression. Decide whether this perturbation leads to a significant alteration in AC005540.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor AC005540.3 expression. Decide whether this perturbation leads to a significant alteration in AC005540.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4418
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of ATF6. Does this perturbation cause a significant change in ATF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of ATF6. Does this perturbation cause a significant change in ATF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":854
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor ZNF292 expression. Decide whether this perturbation leads to a significant alteration in ZNF292 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor ZNF292 expression. Decide whether this perturbation leads to a significant alteration in ZNF292 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3568
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of CLDN11 is measured. Does this perturbation cause a significant change in CLDN11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of CLDN11 is measured. Does this perturbation cause a significant change in CLDN11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4540
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and VAMP2 expression is quantified. Does this perturbation result in a significant change in VAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and VAMP2 expression is quantified. Does this perturbation result in a significant change in VAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2902
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PHF19 is measured. Determine whether PHF19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PHF19 is measured. Determine whether PHF19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3066
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and ANKRD11 expression is observed. Does this perturbation lead to a significant difference in ANKRD11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and ANKRD11 expression is observed. Does this perturbation lead to a significant difference in ANKRD11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4693
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor RSL24D1 expression. Decide whether this perturbation leads to a significant alteration in RSL24D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor RSL24D1 expression. Decide whether this perturbation leads to a significant alteration in RSL24D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":878
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of EPB42. Does this perturbation cause a significant change in EPB42 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of EPB42. Does this perturbation cause a significant change in EPB42 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1714
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and RP13-216E22.4 expression is observed. Does this perturbation lead to a significant difference in RP13-216E22.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and RP13-216E22.4 expression is observed. Does this perturbation lead to a significant difference in RP13-216E22.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2433
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and PITPNB expression is observed. Does this perturbation lead to a significant difference in PITPNB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and PITPNB expression is observed. Does this perturbation lead to a significant difference in PITPNB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3733
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and EIF3A expression is observed. Does this perturbation lead to a significant difference in EIF3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and EIF3A expression is observed. Does this perturbation lead to a significant difference in EIF3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4803
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in EGLN3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in EGLN3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3315
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of OXLD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of OXLD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2857
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of ACE is measured. Does this perturbation cause a significant change in ACE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of ACE is measured. Does this perturbation cause a significant change in ACE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2570
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ZXDA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ZXDA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3935
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and CTNNB1 expression is quantified. Does this perturbation result in a significant change in CTNNB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and CTNNB1 expression is quantified. Does this perturbation result in a significant change in CTNNB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2452
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in IDH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in IDH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2645
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of ZNF292 is measured. Determine whether ZNF292 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of ZNF292 is measured. Determine whether ZNF292 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1506
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor RP11-434H6.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-434H6.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor RP11-434H6.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-434H6.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1898
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of PELO is measured. Does this perturbation cause a significant change in PELO expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of PELO is measured. Does this perturbation cause a significant change in PELO expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3980
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of VIM-AS1. Does perturbing IER3IP1 lead to a significant change in VIM-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of VIM-AS1. Does perturbing IER3IP1 lead to a significant change in VIM-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":481
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of ATP5EP2 is measured. Does this perturbation cause a significant change in ATP5EP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of ATP5EP2 is measured. Does this perturbation cause a significant change in ATP5EP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2950
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and DNMBP expression is measured. Determine whether DNMBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and DNMBP expression is measured. Determine whether DNMBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4019
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1955
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and NFE2 expression is quantified. Does this perturbation result in a significant change in NFE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and NFE2 expression is quantified. Does this perturbation result in a significant change in NFE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":212
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor CD9 expression. Decide whether this perturbation leads to a significant alteration in CD9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor CD9 expression. Decide whether this perturbation leads to a significant alteration in CD9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":428
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ROBO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ROBO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3947
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of TROAP. Does perturbing SARS lead to a significant change in TROAP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of TROAP. Does perturbing SARS lead to a significant change in TROAP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3081
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of VIMP. Does perturbing IDH3A lead to a significant change in VIMP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of VIMP. Does perturbing IDH3A lead to a significant change in VIMP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":971
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in DUT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in DUT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":275
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of WDR3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of WDR3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4567
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of HLA-E. Does this perturbation cause a significant change in HLA-E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of HLA-E. Does this perturbation cause a significant change in HLA-E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3264
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2734
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and RP11-434H6.6 expression is observed. Does this perturbation lead to a significant difference in RP11-434H6.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and RP11-434H6.6 expression is observed. Does this perturbation lead to a significant difference in RP11-434H6.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1893
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor AC008074.3 expression. Decide whether this perturbation leads to a significant alteration in AC008074.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor AC008074.3 expression. Decide whether this perturbation leads to a significant alteration in AC008074.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1908
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor PPM1N expression. Decide whether this perturbation leads to a significant alteration in PPM1N expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor PPM1N expression. Decide whether this perturbation leads to a significant alteration in PPM1N expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3928
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of IDH3A. Does this perturbation cause a significant change in IDH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of IDH3A. Does this perturbation cause a significant change in IDH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2644
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and PAXBP1 expression is quantified. Does this perturbation result in a significant change in PAXBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and PAXBP1 expression is quantified. Does this perturbation result in a significant change in PAXBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4742
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and SNHG10 expression is quantified. Does this perturbation result in a significant change in SNHG10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and SNHG10 expression is quantified. Does this perturbation result in a significant change in SNHG10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1882
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of KCNE3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of KCNE3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1017
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in LPAR5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in LPAR5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and OXLD1 expression is observed. Does this perturbation lead to a significant difference in OXLD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and OXLD1 expression is observed. Does this perturbation lead to a significant difference in OXLD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2853
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and TRIM24 expression is measured. Determine whether TRIM24 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and TRIM24 expression is measured. Determine whether TRIM24 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3199
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of HOTAIRM1 is measured. Does this perturbation cause a significant change in HOTAIRM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of HOTAIRM1 is measured. Does this perturbation cause a significant change in HOTAIRM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1260
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and IDH3A expression is observed. Does this perturbation lead to a significant difference in IDH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and IDH3A expression is observed. Does this perturbation lead to a significant difference in IDH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2643
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor QSER1 expression. Decide whether this perturbation leads to a significant alteration in QSER1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor QSER1 expression. Decide whether this perturbation leads to a significant alteration in QSER1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3008
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in RGS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in RGS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2875
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and KANSL1L expression is quantified. Does this perturbation result in a significant change in KANSL1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and KANSL1L expression is quantified. Does this perturbation result in a significant change in KANSL1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":642
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and ZEB2 expression is quantified. Does this perturbation result in a significant change in ZEB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and ZEB2 expression is quantified. Does this perturbation result in a significant change in ZEB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":962
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor PITPNB expression. Decide whether this perturbation leads to a significant alteration in PITPNB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor PITPNB expression. Decide whether this perturbation leads to a significant alteration in PITPNB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3738
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in COPB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in COPB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":805
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of UHMK1. Does this perturbation cause a significant change in UHMK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of UHMK1. Does this perturbation cause a significant change in UHMK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4984
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of ERV3-1. Does perturbing SRPR lead to a significant change in ERV3-1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of ERV3-1. Does perturbing SRPR lead to a significant change in ERV3-1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":461
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and C10orf32 expression is measured. Determine whether C10orf32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and C10orf32 expression is measured. Determine whether C10orf32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3049
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and TAGLN expression is quantified. Does this perturbation result in a significant change in TAGLN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and TAGLN expression is quantified. Does this perturbation result in a significant change in TAGLN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1352
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of VIMP. Does perturbing COPZ1 lead to a significant change in VIMP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of VIMP. Does perturbing COPZ1 lead to a significant change in VIMP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4581
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and RP11-181G12.2 expression is measured. Determine whether RP11-181G12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and RP11-181G12.2 expression is measured. Determine whether RP11-181G12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4379
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of ZNF789. Does perturbing TTI1 lead to a significant change in ZNF789 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of ZNF789. Does perturbing TTI1 lead to a significant change in ZNF789 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3221
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of ZNF280B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of ZNF280B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1107
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of GRN. Does perturbing SRPRB lead to a significant change in GRN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of GRN. Does perturbing SRPRB lead to a significant change in GRN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4331
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of P4HB is measured. Determine whether P4HB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of P4HB is measured. Determine whether P4HB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4616
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and OXLD1 expression is measured. Determine whether OXLD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and OXLD1 expression is measured. Determine whether OXLD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2859
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor SETD5-AS1 expression. Decide whether this perturbation leads to a significant alteration in SETD5-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor SETD5-AS1 expression. Decide whether this perturbation leads to a significant alteration in SETD5-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1188
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and RP11-640M9.1 expression is measured. Determine whether RP11-640M9.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and RP11-640M9.1 expression is measured. Determine whether RP11-640M9.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1129
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor TTC32 expression. Decide whether this perturbation leads to a significant alteration in TTC32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor TTC32 expression. Decide whether this perturbation leads to a significant alteration in TTC32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3218
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of NPDC1. Does perturbing STT3A lead to a significant change in NPDC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of NPDC1. Does perturbing STT3A lead to a significant change in NPDC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1321
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in RP11-430H10.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in RP11-430H10.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5025
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of CD83. Does perturbing MANF lead to a significant change in CD83 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of CD83. Does perturbing MANF lead to a significant change in CD83 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2691
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of S100A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of S100A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4647
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of NRIP1 is measured. Determine whether NRIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of NRIP1 is measured. Determine whether NRIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3626
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor IRF7 expression. Decide whether this perturbation leads to a significant alteration in IRF7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor IRF7 expression. Decide whether this perturbation leads to a significant alteration in IRF7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":538
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and PRRC2B expression is quantified. Does this perturbation result in a significant change in PRRC2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and PRRC2B expression is quantified. Does this perturbation result in a significant change in PRRC2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":902
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor MANF expression. Decide whether this perturbation leads to a significant alteration in MANF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor MANF expression. Decide whether this perturbation leads to a significant alteration in MANF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2418
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2126
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of PRRC2B. Does perturbing DARS lead to a significant change in PRRC2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of PRRC2B. Does perturbing DARS lead to a significant change in PRRC2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":901
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of NFE2L3 is measured. Does this perturbation cause a significant change in NFE2L3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of NFE2L3 is measured. Does this perturbation cause a significant change in NFE2L3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4820
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor RILPL2 expression. Decide whether this perturbation leads to a significant alteration in RILPL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor RILPL2 expression. Decide whether this perturbation leads to a significant alteration in RILPL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2808
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and GPR146 expression is observed. Does this perturbation lead to a significant difference in GPR146 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and GPR146 expression is observed. Does this perturbation lead to a significant difference in GPR146 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5083
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RP11-141B14.1. Does perturbing ZNF326 lead to a significant change in RP11-141B14.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RP11-141B14.1. Does perturbing ZNF326 lead to a significant change in RP11-141B14.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in CLDN11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in CLDN11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4545
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of EPB42. Does perturbing SYVN1 lead to a significant change in EPB42 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of EPB42. Does perturbing SYVN1 lead to a significant change in EPB42 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1711
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and RP11-360L9.8 expression is measured. Determine whether RP11-360L9.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and RP11-360L9.8 expression is measured. Determine whether RP11-360L9.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4299
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2735
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in PELO expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in PELO expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2115
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of RSL24D1. Does perturbing AMIGO3 lead to a significant change in RSL24D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of RSL24D1. Does perturbing AMIGO3 lead to a significant change in RSL24D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":871
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and MORC2-AS1 expression is measured. Determine whether MORC2-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and MORC2-AS1 expression is measured. Determine whether MORC2-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2559
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor VAMP2 expression. Decide whether this perturbation leads to a significant alteration in VAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor VAMP2 expression. Decide whether this perturbation leads to a significant alteration in VAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2908
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of DST is measured. Determine whether DST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of DST is measured. Determine whether DST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3496
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of RP11-138C9.1. Does this perturbation cause a significant change in RP11-138C9.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of RP11-138C9.1. Does this perturbation cause a significant change in RP11-138C9.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":834
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in AKAP11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in AKAP11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1925
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in LAMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in LAMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2775
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and ATAD2B expression is measured. Determine whether ATAD2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and ATAD2B expression is measured. Determine whether ATAD2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4399
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of PCK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of PCK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3017
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and GCKR expression is measured. Determine whether GCKR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and GCKR expression is measured. Determine whether GCKR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4309
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of ATF7IP2. Does perturbing DHDDS lead to a significant change in ATF7IP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of ATF7IP2. Does perturbing DHDDS lead to a significant change in ATF7IP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4521
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of PRRC2B is measured. Does this perturbation cause a significant change in PRRC2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of PRRC2B is measured. Does this perturbation cause a significant change in PRRC2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":900
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor GNPTG expression. Decide whether this perturbation leads to a significant alteration in GNPTG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor GNPTG expression. Decide whether this perturbation leads to a significant alteration in GNPTG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3098
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of HIST1H2AM. Does this perturbation cause a significant change in HIST1H2AM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of HIST1H2AM. Does this perturbation cause a significant change in HIST1H2AM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2424
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and MEX3B expression is observed. Does this perturbation lead to a significant difference in MEX3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and MEX3B expression is observed. Does this perturbation lead to a significant difference in MEX3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":673
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of PITPNB is measured. Determine whether PITPNB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of PITPNB is measured. Determine whether PITPNB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3736
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and DNTTIP2 expression is measured. Determine whether DNTTIP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and DNTTIP2 expression is measured. Determine whether DNTTIP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":819
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of ANKLE2 is measured. Does this perturbation cause a significant change in ANKLE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of ANKLE2 is measured. Does this perturbation cause a significant change in ANKLE2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2310
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of HERPUD1 is measured. Does this perturbation cause a significant change in HERPUD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of HERPUD1 is measured. Does this perturbation cause a significant change in HERPUD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4430
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and RP11-146D12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-146D12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and RP11-146D12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-146D12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":473
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of PPP4R2 is measured. Does this perturbation cause a significant change in PPP4R2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of PPP4R2 is measured. Does this perturbation cause a significant change in PPP4R2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2370
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of RIMS3 is measured. Determine whether RIMS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of RIMS3 is measured. Determine whether RIMS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":166
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and TSNAXIP1 expression is quantified. Does this perturbation result in a significant change in TSNAXIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and TSNAXIP1 expression is quantified. Does this perturbation result in a significant change in TSNAXIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":752
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RP11-685N10.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RP11-685N10.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2757
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor ZP3 expression. Decide whether this perturbation leads to a significant alteration in ZP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor ZP3 expression. Decide whether this perturbation leads to a significant alteration in ZP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2548
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and TET1 expression is observed. Does this perturbation lead to a significant difference in TET1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and TET1 expression is observed. Does this perturbation lead to a significant difference in TET1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":133
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of CRYM. Does perturbing FARSB lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of CRYM. Does perturbing FARSB lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2531
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and SKIL expression is measured. Determine whether SKIL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and SKIL expression is measured. Determine whether SKIL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2949
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of RP11-666A20.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of RP11-666A20.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4237
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of ZEB1. Does perturbing SAMM50 lead to a significant change in ZEB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of ZEB1. Does perturbing SAMM50 lead to a significant change in ZEB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1381
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and ATP11B expression is quantified. Does this perturbation result in a significant change in ATP11B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and ATP11B expression is quantified. Does this perturbation result in a significant change in ATP11B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":292
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of RP11-863K10.7. Does perturbing DARS lead to a significant change in RP11-863K10.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of RP11-863K10.7. Does perturbing DARS lead to a significant change in RP11-863K10.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":931
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of VIMP is measured. Determine whether VIMP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of VIMP is measured. Determine whether VIMP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":976
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of CTD-2020K17.1 is measured. Does this perturbation cause a significant change in CTD-2020K17.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of CTD-2020K17.1 is measured. Does this perturbation cause a significant change in CTD-2020K17.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4190
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and PHF3 expression is measured. Determine whether PHF3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and PHF3 expression is measured. Determine whether PHF3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of GS1-166A23.1 is measured. Does this perturbation cause a significant change in GS1-166A23.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of GS1-166A23.1 is measured. Does this perturbation cause a significant change in GS1-166A23.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3290
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and USP37 expression is measured. Determine whether USP37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and USP37 expression is measured. Determine whether USP37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1739
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2732
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of LINC00657 is measured. Determine whether LINC00657 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of LINC00657 is measured. Determine whether LINC00657 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":256
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and SMCO1 expression is observed. Does this perturbation lead to a significant difference in SMCO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and SMCO1 expression is observed. Does this perturbation lead to a significant difference in SMCO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4493
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of TSPAN33 is measured. Determine whether TSPAN33 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of TSPAN33 is measured. Determine whether TSPAN33 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3526
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of RP11-304M2.5. Does perturbing DHDDS lead to a significant change in RP11-304M2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of RP11-304M2.5. Does perturbing DHDDS lead to a significant change in RP11-304M2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4531
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and ADAMTS10 expression is measured. Determine whether ADAMTS10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and ADAMTS10 expression is measured. Determine whether ADAMTS10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1079
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of KLF6. Does perturbing TELO2 lead to a significant change in KLF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of KLF6. Does perturbing TELO2 lead to a significant change in KLF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2291
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of LAMP2 is measured. Determine whether LAMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of LAMP2 is measured. Determine whether LAMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5046
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of SLC26A1. Does perturbing DERL2 lead to a significant change in SLC26A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of SLC26A1. Does perturbing DERL2 lead to a significant change in SLC26A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2191
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RIOK3 expression. Decide whether this perturbation leads to a significant alteration in RIOK3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RIOK3 expression. Decide whether this perturbation leads to a significant alteration in RIOK3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and CTNNB1 expression is measured. Determine whether CTNNB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and CTNNB1 expression is measured. Determine whether CTNNB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2459
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and RP11-381O7.3 expression is measured. Determine whether RP11-381O7.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and RP11-381O7.3 expression is measured. Determine whether RP11-381O7.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1559
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in EBI3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in EBI3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1655
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in SHOX2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in SHOX2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":995
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and CEBPG expression is measured. Determine whether CEBPG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and CEBPG expression is measured. Determine whether CEBPG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in PSORS1C1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in PSORS1C1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2275
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of GSN. Does this perturbation cause a significant change in GSN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of GSN. Does this perturbation cause a significant change in GSN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3204
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor KIAA1586 expression. Decide whether this perturbation leads to a significant alteration in KIAA1586 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor KIAA1586 expression. Decide whether this perturbation leads to a significant alteration in KIAA1586 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4658
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and TUBA1C expression is quantified. Does this perturbation result in a significant change in TUBA1C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and TUBA1C expression is quantified. Does this perturbation result in a significant change in TUBA1C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3392
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor SLC26A1 expression. Decide whether this perturbation leads to a significant alteration in SLC26A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor SLC26A1 expression. Decide whether this perturbation leads to a significant alteration in SLC26A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2198
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4576
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and BRWD3 expression is quantified. Does this perturbation result in a significant change in BRWD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and BRWD3 expression is quantified. Does this perturbation result in a significant change in BRWD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":732
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of F2RL2 is measured. Determine whether F2RL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of F2RL2 is measured. Determine whether F2RL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2336
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and RP11-119J18.1 expression is measured. Determine whether RP11-119J18.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and RP11-119J18.1 expression is measured. Determine whether RP11-119J18.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2449
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of SLC37A1. Does this perturbation cause a significant change in SLC37A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of SLC37A1. Does this perturbation cause a significant change in SLC37A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1154
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in RP11-247A12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in RP11-247A12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1665
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of ATF7IP2. Does this perturbation cause a significant change in ATF7IP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of ATF7IP2. Does this perturbation cause a significant change in ATF7IP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4524
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of ZFHX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1137
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and FAM114A1 expression is measured. Determine whether FAM114A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and FAM114A1 expression is measured. Determine whether FAM114A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":719
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor TET1 expression. Decide whether this perturbation leads to a significant alteration in TET1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor TET1 expression. Decide whether this perturbation leads to a significant alteration in TET1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":138
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of CRNDE. Does perturbing TMEM167A lead to a significant change in CRNDE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of CRNDE. Does perturbing TMEM167A lead to a significant change in CRNDE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1971
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of ATP6AP2 is measured. Determine whether ATP6AP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of ATP6AP2 is measured. Determine whether ATP6AP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1626
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of RP11-2H8.2. Does perturbing SRP68 lead to a significant change in RP11-2H8.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of RP11-2H8.2. Does perturbing SRP68 lead to a significant change in RP11-2H8.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3591
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of SNRNP25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of SNRNP25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2157
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of CHD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of CHD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4907
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2722
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and LTN1 expression is quantified. Does this perturbation result in a significant change in LTN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and LTN1 expression is quantified. Does this perturbation result in a significant change in LTN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3132
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of NXF1. Does this perturbation cause a significant change in NXF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of NXF1. Does this perturbation cause a significant change in NXF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3114
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in CDT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in CDT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5125
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ARHGAP5 expression is quantified. Does this perturbation result in a significant change in ARHGAP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ARHGAP5 expression is quantified. Does this perturbation result in a significant change in ARHGAP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3432
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor LRIF1 expression. Decide whether this perturbation leads to a significant alteration in LRIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor LRIF1 expression. Decide whether this perturbation leads to a significant alteration in LRIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1458
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of C9orf64 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of C9orf64 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3877
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of ERP29. Does perturbing SPCS3 lead to a significant change in ERP29 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of ERP29. Does perturbing SPCS3 lead to a significant change in ERP29 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5071
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of TUBA1C is measured. Determine whether TUBA1C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of TUBA1C is measured. Determine whether TUBA1C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3396
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and KCTD1 expression is measured. Determine whether KCTD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and KCTD1 expression is measured. Determine whether KCTD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1379
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor LAMP2 expression. Decide whether this perturbation leads to a significant alteration in LAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor LAMP2 expression. Decide whether this perturbation leads to a significant alteration in LAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5048
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and CTC-550B14.7 expression is quantified. Does this perturbation result in a significant change in CTC-550B14.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and CTC-550B14.7 expression is quantified. Does this perturbation result in a significant change in CTC-550B14.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4552
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of NUF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of NUF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1397
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of KCNQ1OT1. Does perturbing EIF2B3 lead to a significant change in KCNQ1OT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of KCNQ1OT1. Does perturbing EIF2B3 lead to a significant change in KCNQ1OT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4621
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in IFNGR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in IFNGR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2655
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and F2RL2 expression is measured. Determine whether F2RL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and F2RL2 expression is measured. Determine whether F2RL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2339
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of SERPING1 is measured. Determine whether SERPING1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of SERPING1 is measured. Determine whether SERPING1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3246
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and MANF expression is measured. Determine whether MANF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and MANF expression is measured. Determine whether MANF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2079
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of CELF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of CELF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5037
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor IL2RB expression. Decide whether this perturbation leads to a significant alteration in IL2RB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor IL2RB expression. Decide whether this perturbation leads to a significant alteration in IL2RB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3608
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and PELO expression is observed. Does this perturbation lead to a significant difference in PELO expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and PELO expression is observed. Does this perturbation lead to a significant difference in PELO expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2113
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and IRF7 expression is quantified. Does this perturbation result in a significant change in IRF7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and IRF7 expression is quantified. Does this perturbation result in a significant change in IRF7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":532
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of BIRC5 is measured. Does this perturbation cause a significant change in BIRC5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of BIRC5 is measured. Does this perturbation cause a significant change in BIRC5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4500
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and TOPBP1 expression is quantified. Does this perturbation result in a significant change in TOPBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and TOPBP1 expression is quantified. Does this perturbation result in a significant change in TOPBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2892
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of RP11-435O5.4 is measured. Determine whether RP11-435O5.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of RP11-435O5.4 is measured. Determine whether RP11-435O5.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1196
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor KHDC1L expression. Decide whether this perturbation leads to a significant alteration in KHDC1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor KHDC1L expression. Decide whether this perturbation leads to a significant alteration in KHDC1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1068
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and SIGLEC6 expression is observed. Does this perturbation lead to a significant difference in SIGLEC6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and SIGLEC6 expression is observed. Does this perturbation lead to a significant difference in SIGLEC6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3343
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and ATP6AP2 expression is measured. Determine whether ATP6AP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and ATP6AP2 expression is measured. Determine whether ATP6AP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1629
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and CYP17A1-AS1 expression is quantified. Does this perturbation result in a significant change in CYP17A1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and CYP17A1-AS1 expression is quantified. Does this perturbation result in a significant change in CYP17A1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1242
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of PTGS1. Does this perturbation cause a significant change in PTGS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of PTGS1. Does this perturbation cause a significant change in PTGS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3484
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of EXOC3L2. Does this perturbation cause a significant change in EXOC3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of EXOC3L2. Does this perturbation cause a significant change in EXOC3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3354
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and EXO1 expression is measured. Determine whether EXO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and EXO1 expression is measured. Determine whether EXO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2839
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of FAM114A1 is measured. Determine whether FAM114A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of FAM114A1 is measured. Determine whether FAM114A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":716
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and KCTD19 expression is measured. Determine whether KCTD19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and KCTD19 expression is measured. Determine whether KCTD19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2689
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and GSN expression is measured. Determine whether GSN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and GSN expression is measured. Determine whether GSN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3209
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP5 is measured. Does this perturbation cause a significant change in ARHGAP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP5 is measured. Does this perturbation cause a significant change in ARHGAP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3430
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of AKAP11. Does perturbing TMEM167A lead to a significant change in AKAP11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of AKAP11. Does perturbing TMEM167A lead to a significant change in AKAP11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1921
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of DOCK11. Does this perturbation cause a significant change in DOCK11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of DOCK11. Does this perturbation cause a significant change in DOCK11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":364
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and BIRC5 expression is quantified. Does this perturbation result in a significant change in BIRC5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and BIRC5 expression is quantified. Does this perturbation result in a significant change in BIRC5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4502
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of EIF4B. Does this perturbation cause a significant change in EIF4B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of EIF4B. Does this perturbation cause a significant change in EIF4B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4964
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ARHGAP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ARHGAP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3425
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RAI14 expression is measured. Determine whether RAI14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RAI14 expression is measured. Determine whether RAI14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2709
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and RP11-334C17.5 expression is quantified. Does this perturbation result in a significant change in RP11-334C17.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and RP11-334C17.5 expression is quantified. Does this perturbation result in a significant change in RP11-334C17.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1002
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2309
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and TLK2 expression is measured. Determine whether TLK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and TLK2 expression is measured. Determine whether TLK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1999
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of LBX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of LBX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1597
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of RGS20. Does this perturbation cause a significant change in RGS20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of RGS20. Does this perturbation cause a significant change in RGS20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4944
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor TKTL1 expression. Decide whether this perturbation leads to a significant alteration in TKTL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor TKTL1 expression. Decide whether this perturbation leads to a significant alteration in TKTL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":178
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor EGLN3 expression. Decide whether this perturbation leads to a significant alteration in EGLN3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor EGLN3 expression. Decide whether this perturbation leads to a significant alteration in EGLN3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3318
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of RP11-334C17.5 is measured. Determine whether RP11-334C17.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of RP11-334C17.5 is measured. Determine whether RP11-334C17.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1006
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in FAM212A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in FAM212A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2235
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and QSER1 expression is measured. Determine whether QSER1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and QSER1 expression is measured. Determine whether QSER1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5009
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and LTB expression is observed. Does this perturbation lead to a significant difference in LTB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and LTB expression is observed. Does this perturbation lead to a significant difference in LTB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":323
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of PCF11 is measured. Determine whether PCF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of PCF11 is measured. Determine whether PCF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":546
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and PAXBP1 expression is measured. Determine whether PAXBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and PAXBP1 expression is measured. Determine whether PAXBP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4749
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of ZNF678 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of ZNF678 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1367
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and OBSCN expression is quantified. Does this perturbation result in a significant change in OBSCN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and OBSCN expression is quantified. Does this perturbation result in a significant change in OBSCN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3822
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of SMCO1 is measured. Determine whether SMCO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of SMCO1 is measured. Determine whether SMCO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4496
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of SPAST is measured. Does this perturbation cause a significant change in SPAST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of SPAST is measured. Does this perturbation cause a significant change in SPAST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2840
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of PTAR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of PTAR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2107
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of H3F3B is measured. Does this perturbation cause a significant change in H3F3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of H3F3B is measured. Does this perturbation cause a significant change in H3F3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2320
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1690
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor BIRC5 expression. Decide whether this perturbation leads to a significant alteration in BIRC5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor BIRC5 expression. Decide whether this perturbation leads to a significant alteration in BIRC5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4508
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RP11-141B14.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RP11-141B14.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of CDRT4. Does this perturbation cause a significant change in CDRT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of CDRT4. Does this perturbation cause a significant change in CDRT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":284
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in OBSCN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in OBSCN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3825
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of KLF3. Does this perturbation cause a significant change in KLF3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of KLF3. Does this perturbation cause a significant change in KLF3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1984
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of NAV1. Does this perturbation cause a significant change in NAV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of NAV1. Does this perturbation cause a significant change in NAV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4464
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and KIAA1586 expression is quantified. Does this perturbation result in a significant change in KIAA1586 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and KIAA1586 expression is quantified. Does this perturbation result in a significant change in KIAA1586 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4652
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of ANKRD10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of ANKRD10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4357
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of PIK3R3. Does this perturbation cause a significant change in PIK3R3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of PIK3R3. Does this perturbation cause a significant change in PIK3R3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4024
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RGS20 expression is measured. Determine whether RGS20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RGS20 expression is measured. Determine whether RGS20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2719
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of UFD1L. Does this perturbation cause a significant change in UFD1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of UFD1L. Does this perturbation cause a significant change in UFD1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2504
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of POU2F2 is measured. Does this perturbation cause a significant change in POU2F2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of POU2F2 is measured. Does this perturbation cause a significant change in POU2F2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":650
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of C10orf32 is measured. Determine whether C10orf32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of C10orf32 is measured. Determine whether C10orf32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3046
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and PAK1IP1 expression is observed. Does this perturbation lead to a significant difference in PAK1IP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and PAK1IP1 expression is observed. Does this perturbation lead to a significant difference in PAK1IP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4253
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of RP11-363D14.1. Does this perturbation cause a significant change in RP11-363D14.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of RP11-363D14.1. Does this perturbation cause a significant change in RP11-363D14.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3054
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in C9orf64 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in C9orf64 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3875
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of UQCRB. Does perturbing SLMO2 lead to a significant change in UQCRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of UQCRB. Does perturbing SLMO2 lead to a significant change in UQCRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":701
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and RCBTB2 expression is quantified. Does this perturbation result in a significant change in RCBTB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and RCBTB2 expression is quantified. Does this perturbation result in a significant change in RCBTB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1332
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of SNRNP25 is measured. Does this perturbation cause a significant change in SNRNP25 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of SNRNP25 is measured. Does this perturbation cause a significant change in SNRNP25 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2150
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and ATAD2B expression is quantified. Does this perturbation result in a significant change in ATAD2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and ATAD2B expression is quantified. Does this perturbation result in a significant change in ATAD2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4392
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and S100A11 expression is quantified. Does this perturbation result in a significant change in S100A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and S100A11 expression is quantified. Does this perturbation result in a significant change in S100A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4642
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of RGS20 is measured. Does this perturbation cause a significant change in RGS20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of RGS20 is measured. Does this perturbation cause a significant change in RGS20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3120
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of AKAP11 is measured. Does this perturbation cause a significant change in AKAP11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of AKAP11 is measured. Does this perturbation cause a significant change in AKAP11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1920
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor HP1BP3 expression. Decide whether this perturbation leads to a significant alteration in HP1BP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor HP1BP3 expression. Decide whether this perturbation leads to a significant alteration in HP1BP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":618
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of RP3-465N24.6. Does this perturbation cause a significant change in RP3-465N24.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of RP3-465N24.6. Does this perturbation cause a significant change in RP3-465N24.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3584
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in SLC25A35 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in SLC25A35 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3155
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ZFP36L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ZFP36L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3457
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of LTB is measured. Does this perturbation cause a significant change in LTB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of LTB is measured. Does this perturbation cause a significant change in LTB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":320
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and AC005540.3 expression is measured. Determine whether AC005540.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and AC005540.3 expression is measured. Determine whether AC005540.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4419
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and TMOD3 expression is quantified. Does this perturbation result in a significant change in TMOD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and TMOD3 expression is quantified. Does this perturbation result in a significant change in TMOD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1512
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of ATP5EP2. Does perturbing ASCC3 lead to a significant change in ATP5EP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of ATP5EP2. Does perturbing ASCC3 lead to a significant change in ATP5EP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2951
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of PCF11 is measured. Determine whether PCF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of PCF11 is measured. Determine whether PCF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5066
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of RP11-61E11.1. Does this perturbation cause a significant change in RP11-61E11.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of RP11-61E11.1. Does this perturbation cause a significant change in RP11-61E11.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1424
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of PTPN11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of PTPN11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":507
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of EIF3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of EIF3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4807
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of LST1. Does perturbing SYVN1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of LST1. Does perturbing SYVN1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1691
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and CTCFL expression is quantified. Does this perturbation result in a significant change in CTCFL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and CTCFL expression is quantified. Does this perturbation result in a significant change in CTCFL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2602
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of EGLN3 is measured. Does this perturbation cause a significant change in EGLN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of EGLN3 is measured. Does this perturbation cause a significant change in EGLN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3310
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and IL32 expression is measured. Determine whether IL32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and IL32 expression is measured. Determine whether IL32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":569
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and CMTM6 expression is quantified. Does this perturbation result in a significant change in CMTM6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and CMTM6 expression is quantified. Does this perturbation result in a significant change in CMTM6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4912
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of WHAMM. Does perturbing TIMM23 lead to a significant change in WHAMM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of WHAMM. Does perturbing TIMM23 lead to a significant change in WHAMM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":781
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and HRK expression is measured. Determine whether HRK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and HRK expression is measured. Determine whether HRK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1049
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of CTC-308K20.1. Does perturbing SPCS2 lead to a significant change in CTC-308K20.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of CTC-308K20.1. Does perturbing SPCS2 lead to a significant change in CTC-308K20.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5131
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of IFT27 is measured. Does this perturbation cause a significant change in IFT27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of IFT27 is measured. Does this perturbation cause a significant change in IFT27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4220
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of SETD5-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of SETD5-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1187
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and RP11-181G12.2 expression is quantified. Does this perturbation result in a significant change in RP11-181G12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and RP11-181G12.2 expression is quantified. Does this perturbation result in a significant change in RP11-181G12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4372
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and SPAST expression is observed. Does this perturbation lead to a significant difference in SPAST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and SPAST expression is observed. Does this perturbation lead to a significant difference in SPAST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":923
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and SERPING1 expression is quantified. Does this perturbation result in a significant change in SERPING1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and SERPING1 expression is quantified. Does this perturbation result in a significant change in SERPING1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3242
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor CLINT1 expression. Decide whether this perturbation leads to a significant alteration in CLINT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor CLINT1 expression. Decide whether this perturbation leads to a significant alteration in CLINT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":438
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and ZCCHC11 expression is observed. Does this perturbation lead to a significant difference in ZCCHC11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and ZCCHC11 expression is observed. Does this perturbation lead to a significant difference in ZCCHC11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4993
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of DST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of DST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3497
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and NFE2 expression is measured. Determine whether NFE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and NFE2 expression is measured. Determine whether NFE2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":219
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of CTSF. Does this perturbation cause a significant change in CTSF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of CTSF. Does this perturbation cause a significant change in CTSF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":154
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and TROAP expression is measured. Determine whether TROAP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and TROAP expression is measured. Determine whether TROAP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3089
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of MORC2-AS1 is measured. Determine whether MORC2-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of MORC2-AS1 is measured. Determine whether MORC2-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2556
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of DOK3. Does this perturbation cause a significant change in DOK3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of DOK3. Does this perturbation cause a significant change in DOK3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":264
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of RP11-81A22.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of RP11-81A22.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1617
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor HMGCS1 expression. Decide whether this perturbation leads to a significant alteration in HMGCS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor HMGCS1 expression. Decide whether this perturbation leads to a significant alteration in HMGCS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":378
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and SEC23IP expression is measured. Determine whether SEC23IP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and SEC23IP expression is measured. Determine whether SEC23IP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3979
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in RP11-119J18.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in RP11-119J18.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2445
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of RILPL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of RILPL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4147
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor HERC2 expression. Decide whether this perturbation leads to a significant alteration in HERC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor HERC2 expression. Decide whether this perturbation leads to a significant alteration in HERC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":958
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and GCKR expression is quantified. Does this perturbation result in a significant change in GCKR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and GCKR expression is quantified. Does this perturbation result in a significant change in GCKR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4302
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and DUSP21 expression is quantified. Does this perturbation result in a significant change in DUSP21 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and DUSP21 expression is quantified. Does this perturbation result in a significant change in DUSP21 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2742
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of OPTN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of OPTN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":557
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of C1GALT1 is measured. Determine whether C1GALT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of C1GALT1 is measured. Determine whether C1GALT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2006
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and RP11-24F11.2 expression is quantified. Does this perturbation result in a significant change in RP11-24F11.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and RP11-24F11.2 expression is quantified. Does this perturbation result in a significant change in RP11-24F11.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1492
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of HLA-AS1. Does this perturbation cause a significant change in HLA-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of HLA-AS1. Does this perturbation cause a significant change in HLA-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":764
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in BRWD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in BRWD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":735
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of TET1. Does perturbing BHLHE40 lead to a significant change in TET1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of TET1. Does perturbing BHLHE40 lead to a significant change in TET1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":131
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor QSER1 expression. Decide whether this perturbation leads to a significant alteration in QSER1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor QSER1 expression. Decide whether this perturbation leads to a significant alteration in QSER1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5008
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and NINJ2 expression is observed. Does this perturbation lead to a significant difference in NINJ2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and NINJ2 expression is observed. Does this perturbation lead to a significant difference in NINJ2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2143
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and SIGLEC6 expression is measured. Determine whether SIGLEC6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and SIGLEC6 expression is measured. Determine whether SIGLEC6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3349
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of TOPBP1. Does perturbing HYOU1 lead to a significant change in TOPBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of TOPBP1. Does perturbing HYOU1 lead to a significant change in TOPBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3801
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of TOPBP1 is measured. Does this perturbation cause a significant change in TOPBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of TOPBP1 is measured. Does this perturbation cause a significant change in TOPBP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2890
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and ANKRD10 expression is quantified. Does this perturbation result in a significant change in ANKRD10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and ANKRD10 expression is quantified. Does this perturbation result in a significant change in ANKRD10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4352
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in PCK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in PCK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":335
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of PTGS1. Does perturbing SCYL1 lead to a significant change in PTGS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of PTGS1. Does perturbing SCYL1 lead to a significant change in PTGS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3481
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of C17orf64 is measured. Does this perturbation cause a significant change in C17orf64 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of C17orf64 is measured. Does this perturbation cause a significant change in C17orf64 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3710
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and TMEM60 expression is measured. Determine whether TMEM60 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and TMEM60 expression is measured. Determine whether TMEM60 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4979
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PSMD14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PSMD14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3105
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of TOB2. Does this perturbation cause a significant change in TOB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of TOB2. Does this perturbation cause a significant change in TOB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":984
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and BACH2 expression is quantified. Does this perturbation result in a significant change in BACH2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and BACH2 expression is quantified. Does this perturbation result in a significant change in BACH2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3472
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of TMEM87B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of TMEM87B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":827
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of CD9 is measured. Does this perturbation cause a significant change in CD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of CD9 is measured. Does this perturbation cause a significant change in CD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":420
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ARHGAP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ARHGAP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3427
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and ANXA4 expression is quantified. Does this perturbation result in a significant change in ANXA4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and ANXA4 expression is quantified. Does this perturbation result in a significant change in ANXA4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":742
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor NAV1 expression. Decide whether this perturbation leads to a significant alteration in NAV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor NAV1 expression. Decide whether this perturbation leads to a significant alteration in NAV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4468
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and SSBP2 expression is quantified. Does this perturbation result in a significant change in SSBP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and SSBP2 expression is quantified. Does this perturbation result in a significant change in SSBP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4162
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of RP11-445H22.3. Does this perturbation cause a significant change in RP11-445H22.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of RP11-445H22.3. Does this perturbation cause a significant change in RP11-445H22.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3814
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and AC018878.3 expression is measured. Determine whether AC018878.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and AC018878.3 expression is measured. Determine whether AC018878.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3289
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and ATP11B expression is observed. Does this perturbation lead to a significant difference in ATP11B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and ATP11B expression is observed. Does this perturbation lead to a significant difference in ATP11B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":293
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of SPCS2 is measured. Does this perturbation cause a significant change in SPCS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of SPCS2 is measured. Does this perturbation cause a significant change in SPCS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":690
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of RSAD2. Does this perturbation cause a significant change in RSAD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of RSAD2. Does this perturbation cause a significant change in RSAD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4404
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and LTBP1 expression is quantified. Does this perturbation result in a significant change in LTBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and LTBP1 expression is quantified. Does this perturbation result in a significant change in LTBP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1802
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and PDE3B expression is observed. Does this perturbation lead to a significant difference in PDE3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and PDE3B expression is observed. Does this perturbation lead to a significant difference in PDE3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4783
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in ARHGAP30 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in ARHGAP30 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1475
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in DKFZP779L1853 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in DKFZP779L1853 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2385
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of S100A11 is measured. Does this perturbation cause a significant change in S100A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of S100A11 is measured. Does this perturbation cause a significant change in S100A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4640
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PHF19. Does this perturbation cause a significant change in PHF19 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PHF19. Does this perturbation cause a significant change in PHF19 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3064
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and TLK2 expression is quantified. Does this perturbation result in a significant change in TLK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and TLK2 expression is quantified. Does this perturbation result in a significant change in TLK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1992
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of OPTN is measured. Determine whether OPTN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of OPTN is measured. Determine whether OPTN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":556
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and SMIM14 expression is observed. Does this perturbation lead to a significant difference in SMIM14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and SMIM14 expression is observed. Does this perturbation lead to a significant difference in SMIM14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3303
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and BAMBI expression is quantified. Does this perturbation result in a significant change in BAMBI expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and BAMBI expression is quantified. Does this perturbation result in a significant change in BAMBI expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1172
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and CHD3 expression is quantified. Does this perturbation result in a significant change in CHD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and CHD3 expression is quantified. Does this perturbation result in a significant change in CHD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4902
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of LINC00938 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of LINC00938 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4107
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP6 is measured. Does this perturbation cause a significant change in ARHGAP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP6 is measured. Does this perturbation cause a significant change in ARHGAP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3420
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of ARHGAP30 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of ARHGAP30 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1477
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of P4HA2 is measured. Determine whether P4HA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of P4HA2 is measured. Determine whether P4HA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1954
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of ZFHX3 is measured. Determine whether ZFHX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4286
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and NFAT5 expression is measured. Determine whether NFAT5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and NFAT5 expression is measured. Determine whether NFAT5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1819
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of ACSM3 is measured. Determine whether ACSM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of ACSM3 is measured. Determine whether ACSM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2216
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in NFE2L3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in NFE2L3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1585
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of DNMBP is measured. Determine whether DNMBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of DNMBP is measured. Determine whether DNMBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4016
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and SAMM50 expression is measured. Determine whether SAMM50 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and SAMM50 expression is measured. Determine whether SAMM50 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":629
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of NUFIP2. Does this perturbation cause a significant change in NUFIP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of NUFIP2. Does this perturbation cause a significant change in NUFIP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2464
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor UHRF1BP1L expression. Decide whether this perturbation leads to a significant alteration in UHRF1BP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor UHRF1BP1L expression. Decide whether this perturbation leads to a significant alteration in UHRF1BP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":248
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and CENPF expression is observed. Does this perturbation lead to a significant difference in CENPF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and CENPF expression is observed. Does this perturbation lead to a significant difference in CENPF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4063
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in SNHG10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in SNHG10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1315
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor DNTTIP2 expression. Decide whether this perturbation leads to a significant alteration in DNTTIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor DNTTIP2 expression. Decide whether this perturbation leads to a significant alteration in DNTTIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":818
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in GCKR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in GCKR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4305
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and ZFHX3 expression is observed. Does this perturbation lead to a significant difference in ZFHX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2093
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and KHDC1L expression is observed. Does this perturbation lead to a significant difference in KHDC1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and KHDC1L expression is observed. Does this perturbation lead to a significant difference in KHDC1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1063
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of CDKN2C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of CDKN2C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2817
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and IL13RA1 expression is quantified. Does this perturbation result in a significant change in IL13RA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and IL13RA1 expression is quantified. Does this perturbation result in a significant change in IL13RA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2352
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of UBE2V1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of UBE2V1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1707
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of SNHG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of SNHG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4047
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor CENPC expression. Decide whether this perturbation leads to a significant alteration in CENPC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor CENPC expression. Decide whether this perturbation leads to a significant alteration in CENPC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4458
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of CRYM. Does perturbing MARS lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of CRYM. Does perturbing MARS lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2721
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of RP11-15E18.1. Does this perturbation cause a significant change in RP11-15E18.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of RP11-15E18.1. Does this perturbation cause a significant change in RP11-15E18.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4054
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of KHDC1L. Does perturbing IARS2 lead to a significant change in KHDC1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of KHDC1L. Does perturbing IARS2 lead to a significant change in KHDC1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1061
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and RBM12B-AS1 expression is observed. Does this perturbation lead to a significant difference in RBM12B-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and RBM12B-AS1 expression is observed. Does this perturbation lead to a significant difference in RBM12B-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2513
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in SSBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in SSBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4165
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of CTBS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of CTBS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4447
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of KIAA0922 is measured. Does this perturbation cause a significant change in KIAA0922 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of KIAA0922 is measured. Does this perturbation cause a significant change in KIAA0922 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3740
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of RP11-181G12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of RP11-181G12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4377
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and WHSC1 expression is observed. Does this perturbation lead to a significant difference in WHSC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and WHSC1 expression is observed. Does this perturbation lead to a significant difference in WHSC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1483
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of RP11-2H8.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of RP11-2H8.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3597
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of RP11-16E12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of RP11-16E12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3237
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of SSBP2. Does this perturbation cause a significant change in SSBP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of SSBP2. Does this perturbation cause a significant change in SSBP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4164
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and JARID2 expression is observed. Does this perturbation lead to a significant difference in JARID2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and JARID2 expression is observed. Does this perturbation lead to a significant difference in JARID2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1213
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of CST7. Does this perturbation cause a significant change in CST7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of CST7. Does this perturbation cause a significant change in CST7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2204
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of C3AR1. Does perturbing SRP72 lead to a significant change in C3AR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of C3AR1. Does perturbing SRP72 lead to a significant change in C3AR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3401
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor LTBP1 expression. Decide whether this perturbation leads to a significant alteration in LTBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor LTBP1 expression. Decide whether this perturbation leads to a significant alteration in LTBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1808
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of SLBP is measured. Does this perturbation cause a significant change in SLBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of SLBP is measured. Does this perturbation cause a significant change in SLBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2130
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor FAM114A1 expression. Decide whether this perturbation leads to a significant alteration in FAM114A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor FAM114A1 expression. Decide whether this perturbation leads to a significant alteration in FAM114A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":718
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and EPS15 expression is observed. Does this perturbation lead to a significant difference in EPS15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and EPS15 expression is observed. Does this perturbation lead to a significant difference in EPS15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4843
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of TSPAN33. Does this perturbation cause a significant change in TSPAN33 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of TSPAN33. Does this perturbation cause a significant change in TSPAN33 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3524
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of CTSF. Does perturbing BHLHE40 lead to a significant change in CTSF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of CTSF. Does perturbing BHLHE40 lead to a significant change in CTSF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":151
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and AC104532.4 expression is observed. Does this perturbation lead to a significant difference in AC104532.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and AC104532.4 expression is observed. Does this perturbation lead to a significant difference in AC104532.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2983
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of DUT is measured. Does this perturbation cause a significant change in DUT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of DUT is measured. Does this perturbation cause a significant change in DUT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":270
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of YTHDF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of YTHDF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4927
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor RP11-212I21.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-212I21.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor RP11-212I21.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-212I21.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2038
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of P4HA2. Does perturbing MRPL39 lead to a significant change in P4HA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of P4HA2. Does perturbing MRPL39 lead to a significant change in P4HA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2401
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of IFNGR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of IFNGR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2657
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and SOBP expression is observed. Does this perturbation lead to a significant difference in SOBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and SOBP expression is observed. Does this perturbation lead to a significant difference in SOBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3633
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of CTCFL. Does perturbing SEC63 lead to a significant change in CTCFL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of CTCFL. Does perturbing SEC63 lead to a significant change in CTCFL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2601
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and RP11-15E18.1 expression is quantified. Does this perturbation result in a significant change in RP11-15E18.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and RP11-15E18.1 expression is quantified. Does this perturbation result in a significant change in RP11-15E18.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4052
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of NAV2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of NAV2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4867
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor ANKRD11 expression. Decide whether this perturbation leads to a significant alteration in ANKRD11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor ANKRD11 expression. Decide whether this perturbation leads to a significant alteration in ANKRD11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4698
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and AC007038.7 expression is observed. Does this perturbation lead to a significant difference in AC007038.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and AC007038.7 expression is observed. Does this perturbation lead to a significant difference in AC007038.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2923
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor RP11-61E11.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-61E11.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor RP11-61E11.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-61E11.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1428
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and MBNL1 expression is quantified. Does this perturbation result in a significant change in MBNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and MBNL1 expression is quantified. Does this perturbation result in a significant change in MBNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4812
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of LRIF1. Does perturbing MRGBP lead to a significant change in LRIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of LRIF1. Does perturbing MRGBP lead to a significant change in LRIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1451
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of RP11-499F3.2. Does perturbing TARS lead to a significant change in RP11-499F3.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of RP11-499F3.2. Does perturbing TARS lead to a significant change in RP11-499F3.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2881
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of AC079466.1 is measured. Does this perturbation cause a significant change in AC079466.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of AC079466.1 is measured. Does this perturbation cause a significant change in AC079466.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1440
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of PLB1. Does perturbing TMED2 lead to a significant change in PLB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of PLB1. Does perturbing TMED2 lead to a significant change in PLB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4951
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in NUF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in NUF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1395
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of LTN1 is measured. Does this perturbation cause a significant change in LTN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of LTN1 is measured. Does this perturbation cause a significant change in LTN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3130
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of RP11-242O24.5. Does perturbing TMED10 lead to a significant change in RP11-242O24.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of RP11-242O24.5. Does perturbing TMED10 lead to a significant change in RP11-242O24.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3991
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and SERPINF2 expression is measured. Determine whether SERPINF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and SERPINF2 expression is measured. Determine whether SERPINF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3959
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of RSAD2 is measured. Determine whether RSAD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of RSAD2 is measured. Determine whether RSAD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4406
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of ATAD2B is measured. Does this perturbation cause a significant change in ATAD2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of ATAD2B is measured. Does this perturbation cause a significant change in ATAD2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4390
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of PHF21A is measured. Determine whether PHF21A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of PHF21A is measured. Determine whether PHF21A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3856
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in RCBTB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in RCBTB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1335
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of CDCA3 is measured. Determine whether CDCA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of CDCA3 is measured. Determine whether CDCA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4116
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of MED13. Does this perturbation cause a significant change in MED13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of MED13. Does this perturbation cause a significant change in MED13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4314
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of C17orf64. Does this perturbation cause a significant change in C17orf64 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of C17orf64. Does this perturbation cause a significant change in C17orf64 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3714
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and PARP11 expression is quantified. Does this perturbation result in a significant change in PARP11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and PARP11 expression is quantified. Does this perturbation result in a significant change in PARP11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3702
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and SETX expression is quantified. Does this perturbation result in a significant change in SETX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and SETX expression is quantified. Does this perturbation result in a significant change in SETX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3362
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and RP11-322J23.1 expression is measured. Determine whether RP11-322J23.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and RP11-322J23.1 expression is measured. Determine whether RP11-322J23.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4729
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and OR2T6 expression is quantified. Does this perturbation result in a significant change in OR2T6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and OR2T6 expression is quantified. Does this perturbation result in a significant change in OR2T6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1842
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and TRIM24 expression is quantified. Does this perturbation result in a significant change in TRIM24 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and TRIM24 expression is quantified. Does this perturbation result in a significant change in TRIM24 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3192
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of ANKRD10 is measured. Does this perturbation cause a significant change in ANKRD10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of ANKRD10 is measured. Does this perturbation cause a significant change in ANKRD10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4350
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and ABI2 expression is measured. Determine whether ABI2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and ABI2 expression is measured. Determine whether ABI2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2029
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of KIAA0922 is measured. Determine whether KIAA0922 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of KIAA0922 is measured. Determine whether KIAA0922 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3746
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of PTBP3 is measured. Determine whether PTBP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of PTBP3 is measured. Determine whether PTBP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":666
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ROBO1 is measured. Determine whether ROBO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ROBO1 is measured. Determine whether ROBO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3946
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of ATP6V1B2. Does perturbing PDIA6 lead to a significant change in ATP6V1B2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of ATP6V1B2. Does perturbing PDIA6 lead to a significant change in ATP6V1B2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1601
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in CTNNB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in CTNNB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2455
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor ZNF280B expression. Decide whether this perturbation leads to a significant alteration in ZNF280B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor ZNF280B expression. Decide whether this perturbation leads to a significant alteration in ZNF280B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1288
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of KIAA1586. Does perturbing EIF2B3 lead to a significant change in KIAA1586 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of KIAA1586. Does perturbing EIF2B3 lead to a significant change in KIAA1586 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4651
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and PHF21A expression is observed. Does this perturbation lead to a significant difference in PHF21A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and PHF21A expression is observed. Does this perturbation lead to a significant difference in PHF21A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3853
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2045
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and SBF2 expression is measured. Determine whether SBF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and SBF2 expression is measured. Determine whether SBF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2569
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of GMEB1. Does this perturbation cause a significant change in GMEB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of GMEB1. Does this perturbation cause a significant change in GMEB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1204
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor IFT27 expression. Decide whether this perturbation leads to a significant alteration in IFT27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor IFT27 expression. Decide whether this perturbation leads to a significant alteration in IFT27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4228
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in PTAR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in PTAR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2105
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and SPINK5 expression is measured. Determine whether SPINK5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and SPINK5 expression is measured. Determine whether SPINK5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":419
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of OR2T6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of OR2T6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1847
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in LAMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in LAMP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5045
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in CTSF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in CTSF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":155
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of S100A10 is measured. Does this perturbation cause a significant change in S100A10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of S100A10 is measured. Does this perturbation cause a significant change in S100A10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4870
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of AC005540.3 is measured. Does this perturbation cause a significant change in AC005540.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of AC005540.3 is measured. Does this perturbation cause a significant change in AC005540.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4410
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and TMEM60 expression is observed. Does this perturbation lead to a significant difference in TMEM60 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and TMEM60 expression is observed. Does this perturbation lead to a significant difference in TMEM60 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3513
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in P4HA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in P4HA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of PDE4D is measured. Determine whether PDE4D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of PDE4D is measured. Determine whether PDE4D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":516
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of IL2RB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of IL2RB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4007
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of SPEN is measured. Does this perturbation cause a significant change in SPEN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of SPEN is measured. Does this perturbation cause a significant change in SPEN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1570
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor CYP17A1-AS1 expression. Decide whether this perturbation leads to a significant alteration in CYP17A1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor CYP17A1-AS1 expression. Decide whether this perturbation leads to a significant alteration in CYP17A1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1248
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of PTPRC is measured. Determine whether PTPRC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of PTPRC is measured. Determine whether PTPRC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":236
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of STC2. Does perturbing DDIT3 lead to a significant change in STC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of STC2. Does perturbing DDIT3 lead to a significant change in STC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":181
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and SHOX2 expression is quantified. Does this perturbation result in a significant change in SHOX2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and SHOX2 expression is quantified. Does this perturbation result in a significant change in SHOX2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":992
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of HRK. Does perturbing IARS2 lead to a significant change in HRK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of HRK. Does perturbing IARS2 lead to a significant change in HRK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1041
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of RP11-227G15.8 is measured. Does this perturbation cause a significant change in RP11-227G15.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of RP11-227G15.8 is measured. Does this perturbation cause a significant change in RP11-227G15.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2930
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of PDE3B is measured. Determine whether PDE3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of PDE3B is measured. Determine whether PDE3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4786
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of ANKRD11 is measured. Determine whether ANKRD11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of ANKRD11 is measured. Determine whether ANKRD11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4696
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of ZFHX3 is measured. Does this perturbation cause a significant change in ZFHX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1130
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor TRAPPC10 expression. Decide whether this perturbation leads to a significant alteration in TRAPPC10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor TRAPPC10 expression. Decide whether this perturbation leads to a significant alteration in TRAPPC10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1858
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in HERPUD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in HERPUD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4435
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of SLC25A35. Does this perturbation cause a significant change in SLC25A35 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of SLC25A35. Does this perturbation cause a significant change in SLC25A35 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3154
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in SPCS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in SPCS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":695
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of CFH. Does this perturbation cause a significant change in CFH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of CFH. Does this perturbation cause a significant change in CFH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5054
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of UBE3A is measured. Does this perturbation cause a significant change in UBE3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of UBE3A is measured. Does this perturbation cause a significant change in UBE3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1220
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of F2RL2. Does perturbing TELO2 lead to a significant change in F2RL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of F2RL2. Does perturbing TELO2 lead to a significant change in F2RL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2331
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of SLC25A35 is measured. Does this perturbation cause a significant change in SLC25A35 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of SLC25A35 is measured. Does this perturbation cause a significant change in SLC25A35 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3150
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and KCNJ13 expression is measured. Determine whether KCNJ13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and KCNJ13 expression is measured. Determine whether KCNJ13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3659
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP5 is measured. Determine whether ARHGAP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ARHGAP5 is measured. Determine whether ARHGAP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3436
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and HLTF expression is observed. Does this perturbation lead to a significant difference in HLTF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and HLTF expression is observed. Does this perturbation lead to a significant difference in HLTF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2483
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of AC015987.2. Does this perturbation cause a significant change in AC015987.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of AC015987.2. Does this perturbation cause a significant change in AC015987.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2014
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of LTN1. Does this perturbation cause a significant change in LTN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of LTN1. Does this perturbation cause a significant change in LTN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3784
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of TOPBP1. Does this perturbation cause a significant change in TOPBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of TOPBP1. Does this perturbation cause a significant change in TOPBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2894
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of RP11-381O7.3 is measured. Does this perturbation cause a significant change in RP11-381O7.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of RP11-381O7.3 is measured. Does this perturbation cause a significant change in RP11-381O7.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1550
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of RP11-434H6.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of RP11-434H6.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1897
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of KIAA0922 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of KIAA0922 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3747
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor PLB1 expression. Decide whether this perturbation leads to a significant alteration in PLB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor PLB1 expression. Decide whether this perturbation leads to a significant alteration in PLB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4958
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and OPTN expression is quantified. Does this perturbation result in a significant change in OPTN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and OPTN expression is quantified. Does this perturbation result in a significant change in OPTN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":552
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of CMTM6 is measured. Determine whether CMTM6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of CMTM6 is measured. Determine whether CMTM6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4916
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and SDF4 expression is quantified. Does this perturbation result in a significant change in SDF4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and SDF4 expression is quantified. Does this perturbation result in a significant change in SDF4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1772
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PSMD14 expression is quantified. Does this perturbation result in a significant change in PSMD14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PSMD14 expression is quantified. Does this perturbation result in a significant change in PSMD14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3102
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in STC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in STC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":185
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and C12orf44 expression is measured. Determine whether C12orf44 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and C12orf44 expression is measured. Determine whether C12orf44 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1539
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of EIF4B. Does perturbing TMED2 lead to a significant change in EIF4B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of EIF4B. Does perturbing TMED2 lead to a significant change in EIF4B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4961
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor RDH10 expression. Decide whether this perturbation leads to a significant alteration in RDH10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor RDH10 expression. Decide whether this perturbation leads to a significant alteration in RDH10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":148
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of WHSC1. Does perturbing MRGBP lead to a significant change in WHSC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of WHSC1. Does perturbing MRGBP lead to a significant change in WHSC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1481
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of SNHG10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of SNHG10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1317
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of IL2RB. Does this perturbation cause a significant change in IL2RB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of IL2RB. Does this perturbation cause a significant change in IL2RB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3604
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and MANF expression is quantified. Does this perturbation result in a significant change in MANF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and MANF expression is quantified. Does this perturbation result in a significant change in MANF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2412
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in RP11-328J2.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in RP11-328J2.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1095
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor PCK2 expression. Decide whether this perturbation leads to a significant alteration in PCK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor PCK2 expression. Decide whether this perturbation leads to a significant alteration in PCK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3018
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of SLFNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of SLFNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":457
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and RP11-328J2.1 expression is quantified. Does this perturbation result in a significant change in RP11-328J2.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and RP11-328J2.1 expression is quantified. Does this perturbation result in a significant change in RP11-328J2.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1092
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of KDM1B is measured. Does this perturbation cause a significant change in KDM1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of KDM1B is measured. Does this perturbation cause a significant change in KDM1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1160
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of S100A11 is measured. Does this perturbation cause a significant change in S100A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of S100A11 is measured. Does this perturbation cause a significant change in S100A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3250
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and SNHG10 expression is observed. Does this perturbation lead to a significant difference in SNHG10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and SNHG10 expression is observed. Does this perturbation lead to a significant difference in SNHG10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1883
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and JUND expression is measured. Determine whether JUND exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and JUND expression is measured. Determine whether JUND exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":779
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and CTD-2521M24.9 expression is measured. Determine whether CTD-2521M24.9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and CTD-2521M24.9 expression is measured. Determine whether CTD-2521M24.9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2999
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor MS4A6E expression. Decide whether this perturbation leads to a significant alteration in MS4A6E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor MS4A6E expression. Decide whether this perturbation leads to a significant alteration in MS4A6E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":348
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and CTD-2521M24.9 expression is quantified. Does this perturbation result in a significant change in CTD-2521M24.9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and CTD-2521M24.9 expression is quantified. Does this perturbation result in a significant change in CTD-2521M24.9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2992
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and NBEAL2 expression is measured. Determine whether NBEAL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and NBEAL2 expression is measured. Determine whether NBEAL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in CMTM6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in CMTM6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4915
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and ERP29 expression is observed. Does this perturbation lead to a significant difference in ERP29 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and ERP29 expression is observed. Does this perturbation lead to a significant difference in ERP29 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5073
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and ITGB2 expression is quantified. Does this perturbation result in a significant change in ITGB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and ITGB2 expression is quantified. Does this perturbation result in a significant change in ITGB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1302
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in EXO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in EXO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2835
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of TLN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of TLN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1037
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in CTC-550B14.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in CTC-550B14.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4555
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of BIRC5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of BIRC5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4507
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and PTBP3 expression is measured. Determine whether PTBP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and PTBP3 expression is measured. Determine whether PTBP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":669
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor KCNQ1OT1 expression. Decide whether this perturbation leads to a significant alteration in KCNQ1OT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor KCNQ1OT1 expression. Decide whether this perturbation leads to a significant alteration in KCNQ1OT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4628
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of TNFRSF10B. Does perturbing TELO2 lead to a significant change in TNFRSF10B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of TNFRSF10B. Does perturbing TELO2 lead to a significant change in TNFRSF10B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2281
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ARHGAP6 expression is quantified. Does this perturbation result in a significant change in ARHGAP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ARHGAP6 expression is quantified. Does this perturbation result in a significant change in ARHGAP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3902
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and WDR3 expression is quantified. Does this perturbation result in a significant change in WDR3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and WDR3 expression is quantified. Does this perturbation result in a significant change in WDR3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4562
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in CCRL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in CCRL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3555
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of ZEB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of ZEB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1387
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in C10orf32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in C10orf32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3045
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of KCNE3. Does perturbing IDH3A lead to a significant change in KCNE3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of KCNE3. Does perturbing IDH3A lead to a significant change in KCNE3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1011
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of RNF19A. Does perturbing PTDSS1 lead to a significant change in RNF19A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of RNF19A. Does perturbing PTDSS1 lead to a significant change in RNF19A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3761
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of ARHGAP11A. Does perturbing PTDSS1 lead to a significant change in ARHGAP11A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of ARHGAP11A. Does perturbing PTDSS1 lead to a significant change in ARHGAP11A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3721
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of PAXBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of PAXBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4747
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of LTB. Does perturbing SEC61G lead to a significant change in LTB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of LTB. Does perturbing SEC61G lead to a significant change in LTB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4701
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in SLC27A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in SLC27A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3685
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of ROCK1 is measured. Does this perturbation cause a significant change in ROCK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of ROCK1 is measured. Does this perturbation cause a significant change in ROCK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5150
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of TRIM24. Does perturbing TTI1 lead to a significant change in TRIM24 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of TRIM24. Does perturbing TTI1 lead to a significant change in TRIM24 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3191
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and ZNF789 expression is measured. Determine whether ZNF789 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and ZNF789 expression is measured. Determine whether ZNF789 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3229
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and QSER1 expression is observed. Does this perturbation lead to a significant difference in QSER1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and QSER1 expression is observed. Does this perturbation lead to a significant difference in QSER1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5003
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in RILPL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in RILPL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2805
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor CRNDE expression. Decide whether this perturbation leads to a significant alteration in CRNDE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor CRNDE expression. Decide whether this perturbation leads to a significant alteration in CRNDE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1978
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and ZNF280B expression is measured. Determine whether ZNF280B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and ZNF280B expression is measured. Determine whether ZNF280B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1109
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and WDR3 expression is observed. Does this perturbation lead to a significant difference in WDR3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and WDR3 expression is observed. Does this perturbation lead to a significant difference in WDR3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4563
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of ATXN7L3B. Does perturbing TMED2 lead to a significant change in ATXN7L3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of ATXN7L3B. Does perturbing TMED2 lead to a significant change in ATXN7L3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4931
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and THBS1 expression is observed. Does this perturbation lead to a significant difference in THBS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and THBS1 expression is observed. Does this perturbation lead to a significant difference in THBS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5013
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of CYP17A1-AS1. Does this perturbation cause a significant change in CYP17A1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of CYP17A1-AS1. Does this perturbation cause a significant change in CYP17A1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1244
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of IL2RB. Does this perturbation cause a significant change in IL2RB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of IL2RB. Does this perturbation cause a significant change in IL2RB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4004
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of IL2RB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of IL2RB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3607
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of TNFRSF10B. Does this perturbation cause a significant change in TNFRSF10B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of TNFRSF10B. Does this perturbation cause a significant change in TNFRSF10B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3864
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of LRRC4B. Does perturbing DERL2 lead to a significant change in LRRC4B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of LRRC4B. Does perturbing DERL2 lead to a significant change in LRRC4B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2171
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and KCNQ1OT1 expression is measured. Determine whether KCNQ1OT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and KCNQ1OT1 expression is measured. Determine whether KCNQ1OT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4629
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and RP11-304M2.5 expression is measured. Determine whether RP11-304M2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and RP11-304M2.5 expression is measured. Determine whether RP11-304M2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4539
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor LBX1 expression. Decide whether this perturbation leads to a significant alteration in LBX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor LBX1 expression. Decide whether this perturbation leads to a significant alteration in LBX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1598
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and RASGRP2 expression is quantified. Does this perturbation result in a significant change in RASGRP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and RASGRP2 expression is quantified. Does this perturbation result in a significant change in RASGRP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4262
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of SNHG7 is measured. Does this perturbation cause a significant change in SNHG7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of SNHG7 is measured. Does this perturbation cause a significant change in SNHG7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4040
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and ARHGDIB expression is quantified. Does this perturbation result in a significant change in ARHGDIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and ARHGDIB expression is quantified. Does this perturbation result in a significant change in ARHGDIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1962
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of PCF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of PCF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":547
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of RGS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of RGS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4947
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in RP11-15E18.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in RP11-15E18.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4055
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and TKTL1 expression is observed. Does this perturbation lead to a significant difference in TKTL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and TKTL1 expression is observed. Does this perturbation lead to a significant difference in TKTL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":173
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of PELO indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of PELO indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3987
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor SPAST expression. Decide whether this perturbation leads to a significant alteration in SPAST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor SPAST expression. Decide whether this perturbation leads to a significant alteration in SPAST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":928
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and KIF4A expression is measured. Determine whether KIF4A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and KIF4A expression is measured. Determine whether KIF4A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2589
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and AC012594.1 expression is quantified. Does this perturbation result in a significant change in AC012594.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and AC012594.1 expression is quantified. Does this perturbation result in a significant change in AC012594.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1672
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and RPL39 expression is measured. Determine whether RPL39 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and RPL39 expression is measured. Determine whether RPL39 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1749
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of P4HA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of P4HA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of SLC27A2. Does this perturbation cause a significant change in SLC27A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of SLC27A2. Does this perturbation cause a significant change in SLC27A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3684
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and TNFRSF10B expression is quantified. Does this perturbation result in a significant change in TNFRSF10B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and TNFRSF10B expression is quantified. Does this perturbation result in a significant change in TNFRSF10B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3862
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of PTPRC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of PTPRC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":237
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of CTBS. Does this perturbation cause a significant change in CTBS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of CTBS. Does this perturbation cause a significant change in CTBS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4444
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of VIM-AS1 is measured. Determine whether VIM-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of VIM-AS1 is measured. Determine whether VIM-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":486
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor ACSM3 expression. Decide whether this perturbation leads to a significant alteration in ACSM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor ACSM3 expression. Decide whether this perturbation leads to a significant alteration in ACSM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2218
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RGS20. Does this perturbation cause a significant change in RGS20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RGS20. Does this perturbation cause a significant change in RGS20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2714
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of GLG1 is measured. Does this perturbation cause a significant change in GLG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of GLG1 is measured. Does this perturbation cause a significant change in GLG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1940
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and LINC00938 expression is quantified. Does this perturbation result in a significant change in LINC00938 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and LINC00938 expression is quantified. Does this perturbation result in a significant change in LINC00938 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4102
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and KCTD19 expression is observed. Does this perturbation lead to a significant difference in KCTD19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and KCTD19 expression is observed. Does this perturbation lead to a significant difference in KCTD19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2683
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and FCGRT expression is measured. Determine whether FCGRT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and FCGRT expression is measured. Determine whether FCGRT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3539
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of SPAST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of SPAST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":927
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of AP000688.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of AP000688.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3337
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of UQCRB is measured. Does this perturbation cause a significant change in UQCRB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of UQCRB is measured. Does this perturbation cause a significant change in UQCRB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":700
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and RP11-38P22.2 expression is quantified. Does this perturbation result in a significant change in RP11-38P22.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and RP11-38P22.2 expression is quantified. Does this perturbation result in a significant change in RP11-38P22.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1052
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor UBE2V1 expression. Decide whether this perturbation leads to a significant alteration in UBE2V1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor UBE2V1 expression. Decide whether this perturbation leads to a significant alteration in UBE2V1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1708
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of RP11-181G12.2 is measured. Does this perturbation cause a significant change in RP11-181G12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of RP11-181G12.2 is measured. Does this perturbation cause a significant change in RP11-181G12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4370
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and SOBP expression is measured. Determine whether SOBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and SOBP expression is measured. Determine whether SOBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3639
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of CASP8 is measured. Does this perturbation cause a significant change in CASP8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of CASP8 is measured. Does this perturbation cause a significant change in CASP8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":220
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in RP11-445H22.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in RP11-445H22.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3815
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and LTB expression is measured. Determine whether LTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and LTB expression is measured. Determine whether LTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4709
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor HOTAIRM1 expression. Decide whether this perturbation leads to a significant alteration in HOTAIRM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor HOTAIRM1 expression. Decide whether this perturbation leads to a significant alteration in HOTAIRM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1268
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor PTPN11 expression. Decide whether this perturbation leads to a significant alteration in PTPN11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor PTPN11 expression. Decide whether this perturbation leads to a significant alteration in PTPN11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":508
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ARHGAP6. Does this perturbation cause a significant change in ARHGAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ARHGAP6. Does this perturbation cause a significant change in ARHGAP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3904
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in RP11-360L9.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in RP11-360L9.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2795
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and PPP1R16B expression is measured. Determine whether PPP1R16B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and PPP1R16B expression is measured. Determine whether PPP1R16B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":599
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in C6orf48 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in C6orf48 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and RP11-334C17.5 expression is observed. Does this perturbation lead to a significant difference in RP11-334C17.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and RP11-334C17.5 expression is observed. Does this perturbation lead to a significant difference in RP11-334C17.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1003
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and ANKRD11 expression is measured. Determine whether ANKRD11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and ANKRD11 expression is measured. Determine whether ANKRD11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4699
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor NOXA1 expression. Decide whether this perturbation leads to a significant alteration in NOXA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor NOXA1 expression. Decide whether this perturbation leads to a significant alteration in NOXA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1418
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in MANF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in MANF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2415
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of AC015987.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of AC015987.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2017
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3502
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of RDH10. Does perturbing BHLHE40 lead to a significant change in RDH10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of RDH10. Does perturbing BHLHE40 lead to a significant change in RDH10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":141
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor RP13-216E22.4 expression. Decide whether this perturbation leads to a significant alteration in RP13-216E22.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor RP13-216E22.4 expression. Decide whether this perturbation leads to a significant alteration in RP13-216E22.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2438
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of REST is measured. Determine whether REST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of REST is measured. Determine whether REST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":796
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor EIF3A expression. Decide whether this perturbation leads to a significant alteration in EIF3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor EIF3A expression. Decide whether this perturbation leads to a significant alteration in EIF3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4808
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of RP11-573D15.9. Does this perturbation cause a significant change in RP11-573D15.9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of RP11-573D15.9. Does this perturbation cause a significant change in RP11-573D15.9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1294
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of LINC00657. Does perturbing OST4 lead to a significant change in LINC00657 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of LINC00657. Does perturbing OST4 lead to a significant change in LINC00657 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":251
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of NUF2 is measured. Does this perturbation cause a significant change in NUF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of NUF2 is measured. Does this perturbation cause a significant change in NUF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1390
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in DST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in DST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3495
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of TRAPPC10. Does this perturbation cause a significant change in TRAPPC10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of TRAPPC10. Does this perturbation cause a significant change in TRAPPC10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1854
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in LTN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in LTN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3135
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and EPB42 expression is quantified. Does this perturbation result in a significant change in EPB42 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and EPB42 expression is quantified. Does this perturbation result in a significant change in EPB42 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1712
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of PSORS1C1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of PSORS1C1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2277
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of LIMS1 is measured. Determine whether LIMS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of LIMS1 is measured. Determine whether LIMS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3376
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of DNTTIP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of DNTTIP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":817
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of LDLR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of LDLR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":497
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and CASP4 expression is observed. Does this perturbation lead to a significant difference in CASP4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and CASP4 expression is observed. Does this perturbation lead to a significant difference in CASP4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and ADAMTS10 expression is observed. Does this perturbation lead to a significant difference in ADAMTS10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and ADAMTS10 expression is observed. Does this perturbation lead to a significant difference in ADAMTS10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1073
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of RP13-216E22.4 is measured. Does this perturbation cause a significant change in RP13-216E22.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of RP13-216E22.4 is measured. Does this perturbation cause a significant change in RP13-216E22.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2430
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor RTN2 expression. Decide whether this perturbation leads to a significant alteration in RTN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor RTN2 expression. Decide whether this perturbation leads to a significant alteration in RTN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2068
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of BOLA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of BOLA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4637
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of MANF is measured. Does this perturbation cause a significant change in MANF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of MANF is measured. Does this perturbation cause a significant change in MANF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2070
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and LINC00862 expression is observed. Does this perturbation lead to a significant difference in LINC00862 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and LINC00862 expression is observed. Does this perturbation lead to a significant difference in LINC00862 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4593
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of P4HB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of P4HB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4617
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of CASP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of CASP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and DNMBP expression is observed. Does this perturbation lead to a significant difference in DNMBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and DNMBP expression is observed. Does this perturbation lead to a significant difference in DNMBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4013
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of THBS1 is measured. Determine whether THBS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of THBS1 is measured. Determine whether THBS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5016
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and SETD5-AS1 expression is observed. Does this perturbation lead to a significant difference in SETD5-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and SETD5-AS1 expression is observed. Does this perturbation lead to a significant difference in SETD5-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1183
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of CTD-2521M24.9 is measured. Does this perturbation cause a significant change in CTD-2521M24.9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of CTD-2521M24.9 is measured. Does this perturbation cause a significant change in CTD-2521M24.9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2990
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of PCF11 is measured. Does this perturbation cause a significant change in PCF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of PCF11 is measured. Does this perturbation cause a significant change in PCF11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5060
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in RP11-132A1.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in RP11-132A1.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":725
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in ZC3H7A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in ZC3H7A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3675
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of S100A10 is measured. Determine whether S100A10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of S100A10 is measured. Determine whether S100A10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4876
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of LINC00657. Does this perturbation cause a significant change in LINC00657 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of LINC00657. Does this perturbation cause a significant change in LINC00657 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":254
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and KDM1B expression is observed. Does this perturbation lead to a significant difference in KDM1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and KDM1B expression is observed. Does this perturbation lead to a significant difference in KDM1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1163
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor RASGRP2 expression. Decide whether this perturbation leads to a significant alteration in RASGRP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor RASGRP2 expression. Decide whether this perturbation leads to a significant alteration in RASGRP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4268
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and RP11-838N2.4 expression is quantified. Does this perturbation result in a significant change in RP11-838N2.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and RP11-838N2.4 expression is quantified. Does this perturbation result in a significant change in RP11-838N2.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3032
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and HOTAIRM1 expression is observed. Does this perturbation lead to a significant difference in HOTAIRM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and HOTAIRM1 expression is observed. Does this perturbation lead to a significant difference in HOTAIRM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1263
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in RP11-157D23.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in RP11-157D23.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4425
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RP11-141B14.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RP11-141B14.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of BAMBI. Does perturbing QARS lead to a significant change in BAMBI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of BAMBI. Does perturbing QARS lead to a significant change in BAMBI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1271
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of CENPF. Does this perturbation cause a significant change in CENPF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of CENPF. Does this perturbation cause a significant change in CENPF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4064
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and RP11-2H8.2 expression is quantified. Does this perturbation result in a significant change in RP11-2H8.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and RP11-2H8.2 expression is quantified. Does this perturbation result in a significant change in RP11-2H8.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3592
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor ZC3H7A expression. Decide whether this perturbation leads to a significant alteration in ZC3H7A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor ZC3H7A expression. Decide whether this perturbation leads to a significant alteration in ZC3H7A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3678
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of PSMC1. Does perturbing SEC61B lead to a significant change in PSMC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of PSMC1. Does perturbing SEC61B lead to a significant change in PSMC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2821
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of KCNE3. Does this perturbation cause a significant change in KCNE3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of KCNE3. Does this perturbation cause a significant change in KCNE3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1014
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of NPAT is measured. Determine whether NPAT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of NPAT is measured. Determine whether NPAT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3326
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and ITGB2 expression is measured. Determine whether ITGB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and ITGB2 expression is measured. Determine whether ITGB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1309
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of TLN1 is measured. Does this perturbation cause a significant change in TLN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of TLN1 is measured. Does this perturbation cause a significant change in TLN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1030
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of SAMM50 is measured. Does this perturbation cause a significant change in SAMM50 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of SAMM50 is measured. Does this perturbation cause a significant change in SAMM50 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":620
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor LTN1 expression. Decide whether this perturbation leads to a significant alteration in LTN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor LTN1 expression. Decide whether this perturbation leads to a significant alteration in LTN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3138
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of JUND. Does this perturbation cause a significant change in JUND expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of JUND. Does this perturbation cause a significant change in JUND expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":774
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and PIK3R3 expression is quantified. Does this perturbation result in a significant change in PIK3R3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and PIK3R3 expression is quantified. Does this perturbation result in a significant change in PIK3R3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4022
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of IFT27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of IFT27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4227
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of RP11-328J2.1. Does perturbing SOCS1 lead to a significant change in RP11-328J2.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of RP11-328J2.1. Does perturbing SOCS1 lead to a significant change in RP11-328J2.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1091
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and LIMS1 expression is quantified. Does this perturbation result in a significant change in LIMS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and LIMS1 expression is quantified. Does this perturbation result in a significant change in LIMS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3372
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2124
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of DOK3 is measured. Does this perturbation cause a significant change in DOK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of DOK3 is measured. Does this perturbation cause a significant change in DOK3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":260
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in ADAMTS10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in ADAMTS10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1075
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and CHST12 expression is quantified. Does this perturbation result in a significant change in CHST12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and CHST12 expression is quantified. Does this perturbation result in a significant change in CHST12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3462
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in CENPF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in CENPF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4065
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ARHGAP6 expression is measured. Determine whether ARHGAP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ARHGAP6 expression is measured. Determine whether ARHGAP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3429
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and PDE4D expression is quantified. Does this perturbation result in a significant change in PDE4D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and PDE4D expression is quantified. Does this perturbation result in a significant change in PDE4D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":512
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and MYH7B expression is quantified. Does this perturbation result in a significant change in MYH7B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and MYH7B expression is quantified. Does this perturbation result in a significant change in MYH7B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":582
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and LINC01031 expression is measured. Determine whether LINC01031 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and LINC01031 expression is measured. Determine whether LINC01031 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4249
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of PIK3R1 is measured. Determine whether PIK3R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of PIK3R1 is measured. Determine whether PIK3R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5106
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of RASGRP2. Does this perturbation cause a significant change in RASGRP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of RASGRP2. Does this perturbation cause a significant change in RASGRP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4264
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1698
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and LINC00862 expression is quantified. Does this perturbation result in a significant change in LINC00862 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and LINC00862 expression is quantified. Does this perturbation result in a significant change in LINC00862 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4592
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and CD9 expression is measured. Determine whether CD9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and CD9 expression is measured. Determine whether CD9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":429
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and CLDN11 expression is quantified. Does this perturbation result in a significant change in CLDN11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and CLDN11 expression is quantified. Does this perturbation result in a significant change in CLDN11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2612
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of RDH10 is measured. Determine whether RDH10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of RDH10 is measured. Determine whether RDH10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":146
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of TACC3. Does perturbing CAD lead to a significant change in TACC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of TACC3. Does perturbing CAD lead to a significant change in TACC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1861
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of RP11-471M2.3 is measured. Determine whether RP11-471M2.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of RP11-471M2.3 is measured. Determine whether RP11-471M2.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2596
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of ERV3-1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of ERV3-1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":467
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of SDF4 is measured. Determine whether SDF4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of SDF4 is measured. Determine whether SDF4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1776
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RP11-65L19.4 expression is quantified. Does this perturbation result in a significant change in RP11-65L19.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RP11-65L19.4 expression is quantified. Does this perturbation result in a significant change in RP11-65L19.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in CTD-2020K17.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in CTD-2020K17.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4195
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of PLA2G15 is measured. Does this perturbation cause a significant change in PLA2G15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of PLA2G15 is measured. Does this perturbation cause a significant change in PLA2G15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3830
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in CPQ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in CPQ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2965
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and PPP4R2 expression is measured. Determine whether PPP4R2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and PPP4R2 expression is measured. Determine whether PPP4R2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2379
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of CTC-550B14.7 is measured. Does this perturbation cause a significant change in CTC-550B14.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of CTC-550B14.7 is measured. Does this perturbation cause a significant change in CTC-550B14.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4550
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of TMEM60. Does this perturbation cause a significant change in TMEM60 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of TMEM60. Does this perturbation cause a significant change in TMEM60 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3514
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and ANPEP expression is quantified. Does this perturbation result in a significant change in ANPEP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and ANPEP expression is quantified. Does this perturbation result in a significant change in ANPEP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4792
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and AC005540.3 expression is observed. Does this perturbation lead to a significant difference in AC005540.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and AC005540.3 expression is observed. Does this perturbation lead to a significant difference in AC005540.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4413
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and LPAR5 expression is quantified. Does this perturbation result in a significant change in LPAR5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and LPAR5 expression is quantified. Does this perturbation result in a significant change in LPAR5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of ZMYND8. Does perturbing SEL1L lead to a significant change in ZMYND8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of ZMYND8. Does perturbing SEL1L lead to a significant change in ZMYND8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1521
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and NXF1 expression is quantified. Does this perturbation result in a significant change in NXF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and NXF1 expression is quantified. Does this perturbation result in a significant change in NXF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3112
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and SLFNL1 expression is quantified. Does this perturbation result in a significant change in SLFNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and SLFNL1 expression is quantified. Does this perturbation result in a significant change in SLFNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":452
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2047
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor STK17B expression. Decide whether this perturbation leads to a significant alteration in STK17B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor STK17B expression. Decide whether this perturbation leads to a significant alteration in STK17B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4858
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of BOLA3 is measured. Does this perturbation cause a significant change in BOLA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of BOLA3 is measured. Does this perturbation cause a significant change in BOLA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4630
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of NPAT. Does this perturbation cause a significant change in NPAT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of NPAT. Does this perturbation cause a significant change in NPAT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3324
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and RP11-95O2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-95O2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and RP11-95O2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-95O2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4473
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of PAXBP1. Does perturbing DNAJC19 lead to a significant change in PAXBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of PAXBP1. Does perturbing DNAJC19 lead to a significant change in PAXBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4741
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of FCGRT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of FCGRT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3537
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and RP11-322J23.1 expression is observed. Does this perturbation lead to a significant difference in RP11-322J23.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and RP11-322J23.1 expression is observed. Does this perturbation lead to a significant difference in RP11-322J23.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4723
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of NTRK1. Does perturbing CCND3 lead to a significant change in NTRK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of NTRK1. Does perturbing CCND3 lead to a significant change in NTRK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4031
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and BAMBI expression is measured. Determine whether BAMBI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and BAMBI expression is measured. Determine whether BAMBI exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1279
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of RP11-254F7.4. Does this perturbation cause a significant change in RP11-254F7.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of RP11-254F7.4. Does this perturbation cause a significant change in RP11-254F7.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2394
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and RP3-465N24.6 expression is quantified. Does this perturbation result in a significant change in RP3-465N24.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and RP3-465N24.6 expression is quantified. Does this perturbation result in a significant change in RP3-465N24.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3582
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor MORC2-AS1 expression. Decide whether this perturbation leads to a significant alteration in MORC2-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor MORC2-AS1 expression. Decide whether this perturbation leads to a significant alteration in MORC2-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2558
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of PCK2 is measured. Does this perturbation cause a significant change in PCK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of PCK2 is measured. Does this perturbation cause a significant change in PCK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":330
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":847
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of RP11-789C1.1. Does this perturbation cause a significant change in RP11-789C1.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of RP11-789C1.1. Does this perturbation cause a significant change in RP11-789C1.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":944
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and EPB42 expression is observed. Does this perturbation lead to a significant difference in EPB42 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and EPB42 expression is observed. Does this perturbation lead to a significant difference in EPB42 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1713
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and ZMYND8 expression is measured. Determine whether ZMYND8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and ZMYND8 expression is measured. Determine whether ZMYND8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1529
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor RP11-334C17.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-334C17.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor RP11-334C17.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-334C17.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1008
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of RGS20. Does perturbing ARHGAP22 lead to a significant change in RGS20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of RGS20. Does perturbing ARHGAP22 lead to a significant change in RGS20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3121
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in CDCA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in CDCA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4115
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and PPP1R16B expression is observed. Does this perturbation lead to a significant difference in PPP1R16B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and PPP1R16B expression is observed. Does this perturbation lead to a significant difference in PPP1R16B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":593
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and CD83 expression is quantified. Does this perturbation result in a significant change in CD83 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and CD83 expression is quantified. Does this perturbation result in a significant change in CD83 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2692
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of CCDC69. Does perturbing KCTD16 lead to a significant change in CCDC69 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of CCDC69. Does perturbing KCTD16 lead to a significant change in CCDC69 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3441
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of GNPTG. Does this perturbation cause a significant change in GNPTG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of GNPTG. Does this perturbation cause a significant change in GNPTG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3094
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in CYP17A1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in CYP17A1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1245
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor DDIT4 expression. Decide whether this perturbation leads to a significant alteration in DDIT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor DDIT4 expression. Decide whether this perturbation leads to a significant alteration in DDIT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1828
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of ACRV1 is measured. Determine whether ACRV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of ACRV1 is measured. Determine whether ACRV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3896
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in PCF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in PCF11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":545
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and SETX expression is observed. Does this perturbation lead to a significant difference in SETX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and SETX expression is observed. Does this perturbation lead to a significant difference in SETX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3363
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and HLTF expression is quantified. Does this perturbation result in a significant change in HLTF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and HLTF expression is quantified. Does this perturbation result in a significant change in HLTF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2482
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and PIK3R3 expression is observed. Does this perturbation lead to a significant difference in PIK3R3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and PIK3R3 expression is observed. Does this perturbation lead to a significant difference in PIK3R3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4023
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of HP1BP3 is measured. Does this perturbation cause a significant change in HP1BP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of HP1BP3 is measured. Does this perturbation cause a significant change in HP1BP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":610
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of RP11-423O2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of RP11-423O2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":307
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of MED13. Does perturbing AARS lead to a significant change in MED13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of MED13. Does perturbing AARS lead to a significant change in MED13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4311
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and DUSP21 expression is measured. Determine whether DUSP21 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and DUSP21 expression is measured. Determine whether DUSP21 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2749
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of SAMM50 is measured. Determine whether SAMM50 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of SAMM50 is measured. Determine whether SAMM50 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":626
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and SBF2 expression is observed. Does this perturbation lead to a significant difference in SBF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and SBF2 expression is observed. Does this perturbation lead to a significant difference in SBF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2563
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of SOBP is measured. Determine whether SOBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of SOBP is measured. Determine whether SOBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3636
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of HIST1H2AM is measured. Determine whether HIST1H2AM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of HIST1H2AM is measured. Determine whether HIST1H2AM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2426
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and PTGS1 expression is observed. Does this perturbation lead to a significant difference in PTGS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and PTGS1 expression is observed. Does this perturbation lead to a significant difference in PTGS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3483
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of VIMP is measured. Does this perturbation cause a significant change in VIMP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of VIMP is measured. Does this perturbation cause a significant change in VIMP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4580
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and AC008074.3 expression is measured. Determine whether AC008074.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and AC008074.3 expression is measured. Determine whether AC008074.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1909
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of IL32. Does this perturbation cause a significant change in IL32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of IL32. Does this perturbation cause a significant change in IL32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":564
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and TLK2 expression is observed. Does this perturbation lead to a significant difference in TLK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and TLK2 expression is observed. Does this perturbation lead to a significant difference in TLK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4763
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor RP11-38P22.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-38P22.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor RP11-38P22.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-38P22.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1058
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of CYP17A1-AS1 is measured. Does this perturbation cause a significant change in CYP17A1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of CYP17A1-AS1 is measured. Does this perturbation cause a significant change in CYP17A1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1240
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ZXDA is measured. Determine whether ZXDA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ZXDA is measured. Determine whether ZXDA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3936
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and SLC27A2 expression is measured. Determine whether SLC27A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and SLC27A2 expression is measured. Determine whether SLC27A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3689
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in ESCO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in ESCO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":865
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and POLR2J3 expression is quantified. Does this perturbation result in a significant change in POLR2J3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and POLR2J3 expression is quantified. Does this perturbation result in a significant change in POLR2J3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3792
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of NRIP1. Does perturbing BHLHE40 lead to a significant change in NRIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of NRIP1. Does perturbing BHLHE40 lead to a significant change in NRIP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in PSMC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in PSMC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2825
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in DNTTIP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in DNTTIP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":815
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and SETD5-AS1 expression is quantified. Does this perturbation result in a significant change in SETD5-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and SETD5-AS1 expression is quantified. Does this perturbation result in a significant change in SETD5-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1182
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in TMEM60 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in TMEM60 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3515
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and PPM1N expression is measured. Determine whether PPM1N exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and PPM1N expression is measured. Determine whether PPM1N exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3929
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and KDM1B expression is measured. Determine whether KDM1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and KDM1B expression is measured. Determine whether KDM1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1169
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":849
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and P4HA2 expression is observed. Does this perturbation lead to a significant difference in P4HA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and P4HA2 expression is observed. Does this perturbation lead to a significant difference in P4HA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2403
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of QSER1. Does this perturbation cause a significant change in QSER1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of QSER1. Does this perturbation cause a significant change in QSER1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3004
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of STC2 is measured. Does this perturbation cause a significant change in STC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of STC2 is measured. Does this perturbation cause a significant change in STC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":180
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and LINC00657 expression is quantified. Does this perturbation result in a significant change in LINC00657 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and LINC00657 expression is quantified. Does this perturbation result in a significant change in LINC00657 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":252
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of SRP72. Does this perturbation cause a significant change in SRP72 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of SRP72. Does this perturbation cause a significant change in SRP72 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1234
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and IL2RB expression is observed. Does this perturbation lead to a significant difference in IL2RB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and IL2RB expression is observed. Does this perturbation lead to a significant difference in IL2RB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4003
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of AC018878.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of AC018878.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3287
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RIOK3. Does this perturbation cause a significant change in RIOK3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RIOK3. Does this perturbation cause a significant change in RIOK3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in AC005540.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in AC005540.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4415
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of CASP4. Does perturbing CREB1 lead to a significant change in CASP4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of CASP4. Does perturbing CREB1 lead to a significant change in CASP4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of MLEC is measured. Does this perturbation cause a significant change in MLEC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of MLEC is measured. Does this perturbation cause a significant change in MLEC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3170
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and MEX3B expression is quantified. Does this perturbation result in a significant change in MEX3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and MEX3B expression is quantified. Does this perturbation result in a significant change in MEX3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":672
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of RP11-132A1.4 is measured. Determine whether RP11-132A1.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of RP11-132A1.4 is measured. Determine whether RP11-132A1.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":726
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of KHDC1L is measured. Determine whether KHDC1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of KHDC1L is measured. Determine whether KHDC1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1066
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of MEX3B. Does this perturbation cause a significant change in MEX3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of MEX3B. Does this perturbation cause a significant change in MEX3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":674
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of CTC-550B14.7 is measured. Determine whether CTC-550B14.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of CTC-550B14.7 is measured. Determine whether CTC-550B14.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4556
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor CTC-550B14.7 expression. Decide whether this perturbation leads to a significant alteration in CTC-550B14.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor CTC-550B14.7 expression. Decide whether this perturbation leads to a significant alteration in CTC-550B14.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4558
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of UBE3A. Does this perturbation cause a significant change in UBE3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of UBE3A. Does this perturbation cause a significant change in UBE3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1224
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in WDR72 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in WDR72 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4135
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":845
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of VAMP2. Does perturbing TARS lead to a significant change in VAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of VAMP2. Does perturbing TARS lead to a significant change in VAMP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2901
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of LTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of LTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":327
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of FYTTD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of FYTTD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2367
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4579
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in ASPM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in ASPM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2665
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in C19orf59 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in C19orf59 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2345
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and CLDN11 expression is measured. Determine whether CLDN11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and CLDN11 expression is measured. Determine whether CLDN11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2619
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of RP11-640M9.1 is measured. Determine whether RP11-640M9.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of RP11-640M9.1 is measured. Determine whether RP11-640M9.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1126
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and HP1BP3 expression is measured. Determine whether HP1BP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and HP1BP3 expression is measured. Determine whether HP1BP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":619
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in IFT27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in IFT27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4225
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of ATAD2B. Does this perturbation cause a significant change in ATAD2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of ATAD2B. Does this perturbation cause a significant change in ATAD2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4394
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor C6orf120 expression. Decide whether this perturbation leads to a significant alteration in C6orf120 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor C6orf120 expression. Decide whether this perturbation leads to a significant alteration in C6orf120 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2268
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of CTD-2521M24.9. Does perturbing ASCC3 lead to a significant change in CTD-2521M24.9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of CTD-2521M24.9. Does perturbing ASCC3 lead to a significant change in CTD-2521M24.9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2991
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and RP11-212I21.4 expression is observed. Does this perturbation lead to a significant difference in RP11-212I21.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and RP11-212I21.4 expression is observed. Does this perturbation lead to a significant difference in RP11-212I21.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2033
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor CFH expression. Decide whether this perturbation leads to a significant alteration in CFH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor CFH expression. Decide whether this perturbation leads to a significant alteration in CFH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5058
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and GRN expression is measured. Determine whether GRN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and GRN expression is measured. Determine whether GRN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4339
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and PCF11 expression is observed. Does this perturbation lead to a significant difference in PCF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and PCF11 expression is observed. Does this perturbation lead to a significant difference in PCF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5063
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of CTD-2020K17.1. Does perturbing COPB1 lead to a significant change in CTD-2020K17.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of CTD-2020K17.1. Does perturbing COPB1 lead to a significant change in CTD-2020K17.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4191
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of AC096559.1. Does this perturbation cause a significant change in AC096559.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of AC096559.1. Does this perturbation cause a significant change in AC096559.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1874
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of USP37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of USP37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1737
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and ZEB2 expression is observed. Does this perturbation lead to a significant difference in ZEB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and ZEB2 expression is observed. Does this perturbation lead to a significant difference in ZEB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":963
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of P4HA2 is measured. Determine whether P4HA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of P4HA2 is measured. Determine whether P4HA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2406
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor REST expression. Decide whether this perturbation leads to a significant alteration in REST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor REST expression. Decide whether this perturbation leads to a significant alteration in REST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":798
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of TMEM60 is measured. Does this perturbation cause a significant change in TMEM60 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of TMEM60 is measured. Does this perturbation cause a significant change in TMEM60 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4970
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and C3AR1 expression is observed. Does this perturbation lead to a significant difference in C3AR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and C3AR1 expression is observed. Does this perturbation lead to a significant difference in C3AR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3403
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in TNFRSF10B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in TNFRSF10B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3865
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and MED13 expression is measured. Determine whether MED13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and MED13 expression is measured. Determine whether MED13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4319
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of CMTM6. Does perturbing CARS lead to a significant change in CMTM6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of CMTM6. Does perturbing CARS lead to a significant change in CMTM6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4911
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of C1GALT1. Does perturbing GNPNAT1 lead to a significant change in C1GALT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of C1GALT1. Does perturbing GNPNAT1 lead to a significant change in C1GALT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2001
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RP11-65L19.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RP11-65L19.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and RP11-247A12.2 expression is quantified. Does this perturbation result in a significant change in RP11-247A12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and RP11-247A12.2 expression is quantified. Does this perturbation result in a significant change in RP11-247A12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1662
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of CLINT1. Does perturbing SRPR lead to a significant change in CLINT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of CLINT1. Does perturbing SRPR lead to a significant change in CLINT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":431
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of ZP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of ZP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2547
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in CDK13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in CDK13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2765
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of TOPBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of TOPBP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2897
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of RP11-666A20.4 is measured. Does this perturbation cause a significant change in RP11-666A20.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of RP11-666A20.4 is measured. Does this perturbation cause a significant change in RP11-666A20.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4230
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor ANPEP expression. Decide whether this perturbation leads to a significant alteration in ANPEP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor ANPEP expression. Decide whether this perturbation leads to a significant alteration in ANPEP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4798
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and TTC18 expression is quantified. Does this perturbation result in a significant change in TTC18 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and TTC18 expression is quantified. Does this perturbation result in a significant change in TTC18 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3692
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of GPR146 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of GPR146 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5087
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of RP11-434H6.6 is measured. Does this perturbation cause a significant change in RP11-434H6.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of RP11-434H6.6 is measured. Does this perturbation cause a significant change in RP11-434H6.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1890
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of CLDN11. Does perturbing DHDDS lead to a significant change in CLDN11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of CLDN11. Does perturbing DHDDS lead to a significant change in CLDN11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4541
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of LDLR. Does perturbing IER3IP1 lead to a significant change in LDLR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of LDLR. Does perturbing IER3IP1 lead to a significant change in LDLR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":491
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and VIMP expression is observed. Does this perturbation lead to a significant difference in VIMP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and VIMP expression is observed. Does this perturbation lead to a significant difference in VIMP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":973
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in PITPNB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in PITPNB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3735
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and RP11-15E18.1 expression is measured. Determine whether RP11-15E18.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and RP11-15E18.1 expression is measured. Determine whether RP11-15E18.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4059
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of ERP29 is measured. Does this perturbation cause a significant change in ERP29 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of ERP29 is measured. Does this perturbation cause a significant change in ERP29 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5070
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor RP11-863K10.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-863K10.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor RP11-863K10.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-863K10.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":938
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and RP11-423O2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-423O2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and RP11-423O2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-423O2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":303
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and KCTD1 expression is observed. Does this perturbation lead to a significant difference in KCTD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and KCTD1 expression is observed. Does this perturbation lead to a significant difference in KCTD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1373
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of PDK2 is measured. Does this perturbation cause a significant change in PDK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of PDK2 is measured. Does this perturbation cause a significant change in PDK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2160
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and C19orf59 expression is quantified. Does this perturbation result in a significant change in C19orf59 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and C19orf59 expression is quantified. Does this perturbation result in a significant change in C19orf59 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2342
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in LINC00938 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in LINC00938 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4105
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in SETD5-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in SETD5-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1185
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of C12orf23 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of C12orf23 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1767
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor PHF21A expression. Decide whether this perturbation leads to a significant alteration in PHF21A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor PHF21A expression. Decide whether this perturbation leads to a significant alteration in PHF21A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3858
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and PELO expression is measured. Determine whether PELO exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and PELO expression is measured. Determine whether PELO exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3989
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor ZEB2 expression. Decide whether this perturbation leads to a significant alteration in ZEB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor ZEB2 expression. Decide whether this perturbation leads to a significant alteration in ZEB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":968
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in RP11-381O7.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in RP11-381O7.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1555
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and VAMP2 expression is measured. Determine whether VAMP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and VAMP2 expression is measured. Determine whether VAMP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2909
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of RP11-3D4.3 is measured. Does this perturbation cause a significant change in RP11-3D4.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of RP11-3D4.3 is measured. Does this perturbation cause a significant change in RP11-3D4.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3640
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of CDRT4 is measured. Does this perturbation cause a significant change in CDRT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of CDRT4 is measured. Does this perturbation cause a significant change in CDRT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":280
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of CHST12. Does this perturbation cause a significant change in CHST12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of CHST12. Does this perturbation cause a significant change in CHST12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3464
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and RP11-2H8.2 expression is measured. Determine whether RP11-2H8.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and RP11-2H8.2 expression is measured. Determine whether RP11-2H8.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3599
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and HIST1H1D expression is quantified. Does this perturbation result in a significant change in HIST1H1D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and HIST1H1D expression is quantified. Does this perturbation result in a significant change in HIST1H1D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4342
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and AC015987.2 expression is measured. Determine whether AC015987.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and AC015987.2 expression is measured. Determine whether AC015987.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2019
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and RTN2 expression is quantified. Does this perturbation result in a significant change in RTN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and RTN2 expression is quantified. Does this perturbation result in a significant change in RTN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2062
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and GLG1 expression is observed. Does this perturbation lead to a significant difference in GLG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and GLG1 expression is observed. Does this perturbation lead to a significant difference in GLG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1943
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and ASPM expression is quantified. Does this perturbation result in a significant change in ASPM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and ASPM expression is quantified. Does this perturbation result in a significant change in ASPM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2662
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of TTC32. Does this perturbation cause a significant change in TTC32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of TTC32. Does this perturbation cause a significant change in TTC32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3214
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and SAMM50 expression is observed. Does this perturbation lead to a significant difference in SAMM50 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and SAMM50 expression is observed. Does this perturbation lead to a significant difference in SAMM50 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":623
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and ATXN7L3B expression is quantified. Does this perturbation result in a significant change in ATXN7L3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and ATXN7L3B expression is quantified. Does this perturbation result in a significant change in ATXN7L3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4932
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in SOBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in SOBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3635
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of CLINT1 is measured. Determine whether CLINT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of CLINT1 is measured. Determine whether CLINT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":436
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor NFE2L3 expression. Decide whether this perturbation leads to a significant alteration in NFE2L3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor NFE2L3 expression. Decide whether this perturbation leads to a significant alteration in NFE2L3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4828
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of ANXA4 is measured. Does this perturbation cause a significant change in ANXA4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of ANXA4 is measured. Does this perturbation cause a significant change in ANXA4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":740
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of GOT1. Does this perturbation cause a significant change in GOT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of GOT1. Does this perturbation cause a significant change in GOT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1114
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and TUBA1C expression is measured. Determine whether TUBA1C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and TUBA1C expression is measured. Determine whether TUBA1C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3399
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of NCKAP1L is measured. Determine whether NCKAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of NCKAP1L is measured. Determine whether NCKAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":446
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and IL13RA1 expression is measured. Determine whether IL13RA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and IL13RA1 expression is measured. Determine whether IL13RA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2359
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of FOXO6 is measured. Does this perturbation cause a significant change in FOXO6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of FOXO6 is measured. Does this perturbation cause a significant change in FOXO6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4120
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of SLC27A2 is measured. Does this perturbation cause a significant change in SLC27A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of SLC27A2 is measured. Does this perturbation cause a significant change in SLC27A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3680
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RP11-65L19.4 is measured. Determine whether RP11-65L19.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RP11-65L19.4 is measured. Determine whether RP11-65L19.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of CDT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of CDT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5127
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor PDE4D expression. Decide whether this perturbation leads to a significant alteration in PDE4D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor PDE4D expression. Decide whether this perturbation leads to a significant alteration in PDE4D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":518
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in PDE3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in PDE3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4785
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of TGOLN2 is measured. Does this perturbation cause a significant change in TGOLN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of TGOLN2 is measured. Does this perturbation cause a significant change in TGOLN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5090
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor DNASE2 expression. Decide whether this perturbation leads to a significant alteration in DNASE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor DNASE2 expression. Decide whether this perturbation leads to a significant alteration in DNASE2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1638
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor HLA-AS1 expression. Decide whether this perturbation leads to a significant alteration in HLA-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor HLA-AS1 expression. Decide whether this perturbation leads to a significant alteration in HLA-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":768
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and VIM-AS1 expression is measured. Determine whether VIM-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and VIM-AS1 expression is measured. Determine whether VIM-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":489
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and GOT1 expression is observed. Does this perturbation lead to a significant difference in GOT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and GOT1 expression is observed. Does this perturbation lead to a significant difference in GOT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1113
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of PIK3IP1. Does perturbing SEC61B lead to a significant change in PIK3IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of PIK3IP1. Does perturbing SEC61B lead to a significant change in PIK3IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2861
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in AP000688.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in AP000688.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3335
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and NBEAL2 expression is quantified. Does this perturbation result in a significant change in NBEAL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and NBEAL2 expression is quantified. Does this perturbation result in a significant change in NBEAL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of IDS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of IDS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4277
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of TFPI is measured. Determine whether TFPI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of TFPI is measured. Determine whether TFPI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3916
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of LINC00862. Does perturbing COPZ1 lead to a significant change in LINC00862 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of LINC00862. Does perturbing COPZ1 lead to a significant change in LINC00862 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4591
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and PGM3 expression is observed. Does this perturbation lead to a significant difference in PGM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and PGM3 expression is observed. Does this perturbation lead to a significant difference in PGM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2083
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of RP11-434H6.6. Does perturbing CAD lead to a significant change in RP11-434H6.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of RP11-434H6.6. Does perturbing CAD lead to a significant change in RP11-434H6.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1891
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of TTC18. Does this perturbation cause a significant change in TTC18 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of TTC18. Does this perturbation cause a significant change in TTC18 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3694
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of CTD-2267D19.3 is measured. Does this perturbation cause a significant change in CTD-2267D19.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of CTD-2267D19.3 is measured. Does this perturbation cause a significant change in CTD-2267D19.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1540
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and RGS3 expression is observed. Does this perturbation lead to a significant difference in RGS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and RGS3 expression is observed. Does this perturbation lead to a significant difference in RGS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2873
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of CPQ. Does this perturbation cause a significant change in CPQ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of CPQ. Does this perturbation cause a significant change in CPQ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2964
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of DST. Does perturbing SCYL1 lead to a significant change in DST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of DST. Does perturbing SCYL1 lead to a significant change in DST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3491
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in FOXO6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in FOXO6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4125
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of TRAPPC10 is measured. Determine whether TRAPPC10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of TRAPPC10 is measured. Determine whether TRAPPC10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1856
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of CST7 is measured. Does this perturbation cause a significant change in CST7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of CST7 is measured. Does this perturbation cause a significant change in CST7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2200
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of AC079466.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of AC079466.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1447
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor RP11-181G12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-181G12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor RP11-181G12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-181G12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4378
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor LAMP2 expression. Decide whether this perturbation leads to a significant alteration in LAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor LAMP2 expression. Decide whether this perturbation leads to a significant alteration in LAMP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2778
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of HPCAL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of HPCAL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2977
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of SAMM50. Does perturbing HARS lead to a significant change in SAMM50 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of SAMM50. Does perturbing HARS lead to a significant change in SAMM50 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":621
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and KLF3 expression is observed. Does this perturbation lead to a significant difference in KLF3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and KLF3 expression is observed. Does this perturbation lead to a significant difference in KLF3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1983
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and CST7 expression is observed. Does this perturbation lead to a significant difference in CST7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and CST7 expression is observed. Does this perturbation lead to a significant difference in CST7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2203
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of RP11-423O2.5. Does this perturbation cause a significant change in RP11-423O2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of RP11-423O2.5. Does this perturbation cause a significant change in RP11-423O2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":304
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of C9orf64 is measured. Determine whether C9orf64 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of C9orf64 is measured. Determine whether C9orf64 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3876
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of DSC2 is measured. Determine whether DSC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of DSC2 is measured. Determine whether DSC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4096
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in TMEM87B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in TMEM87B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":825
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of ZEB1 is measured. Determine whether ZEB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of ZEB1 is measured. Determine whether ZEB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1386
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and REST expression is observed. Does this perturbation lead to a significant difference in REST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and REST expression is observed. Does this perturbation lead to a significant difference in REST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":793
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of HLA-AS1. Does perturbing DAD1 lead to a significant change in HLA-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of HLA-AS1. Does perturbing DAD1 lead to a significant change in HLA-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":761
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of RP11-360L9.8 is measured. Determine whether RP11-360L9.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of RP11-360L9.8 is measured. Determine whether RP11-360L9.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4296
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor ANXA4 expression. Decide whether this perturbation leads to a significant alteration in ANXA4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor ANXA4 expression. Decide whether this perturbation leads to a significant alteration in ANXA4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":748
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor ATF7IP2 expression. Decide whether this perturbation leads to a significant alteration in ATF7IP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor ATF7IP2 expression. Decide whether this perturbation leads to a significant alteration in ATF7IP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4528
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of ZNF292 is measured. Does this perturbation cause a significant change in ZNF292 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of ZNF292 is measured. Does this perturbation cause a significant change in ZNF292 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1500
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in RPL39 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in RPL39 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1745
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in PDE9A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in PDE9A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":195
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and RP11-573D15.9 expression is quantified. Does this perturbation result in a significant change in RP11-573D15.9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and RP11-573D15.9 expression is quantified. Does this perturbation result in a significant change in RP11-573D15.9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1292
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of NUFIP2. Does perturbing GBF1 lead to a significant change in NUFIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of NUFIP2. Does perturbing GBF1 lead to a significant change in NUFIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2461
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of CTSF is measured. Determine whether CTSF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of CTSF is measured. Determine whether CTSF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":156
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of TUBA1C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of TUBA1C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3397
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and IFT27 expression is quantified. Does this perturbation result in a significant change in IFT27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and IFT27 expression is quantified. Does this perturbation result in a significant change in IFT27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4222
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and TTC32 expression is measured. Determine whether TTC32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and TTC32 expression is measured. Determine whether TTC32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3219
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of BAMBI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of BAMBI indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1277
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of GALNT7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of GALNT7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4387
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of AC008074.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of AC008074.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1907
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and ATF6 expression is quantified. Does this perturbation result in a significant change in ATF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and ATF6 expression is quantified. Does this perturbation result in a significant change in ATF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":852
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and UBE2V1 expression is quantified. Does this perturbation result in a significant change in UBE2V1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and UBE2V1 expression is quantified. Does this perturbation result in a significant change in UBE2V1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1702
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and PSMC1 expression is observed. Does this perturbation lead to a significant difference in PSMC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and PSMC1 expression is observed. Does this perturbation lead to a significant difference in PSMC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2823
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and MBNL1 expression is observed. Does this perturbation lead to a significant difference in MBNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and MBNL1 expression is observed. Does this perturbation lead to a significant difference in MBNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4813
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of CLDN11. Does this perturbation cause a significant change in CLDN11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of CLDN11. Does this perturbation cause a significant change in CLDN11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4544
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of GDF11 is measured. Determine whether GDF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of GDF11 is measured. Determine whether GDF11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":396
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of LAMP2 is measured. Determine whether LAMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of LAMP2 is measured. Determine whether LAMP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2776
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of RP11-390B4.5 is measured. Does this perturbation cause a significant change in RP11-390B4.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of RP11-390B4.5 is measured. Does this perturbation cause a significant change in RP11-390B4.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4830
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor CEBPG expression. Decide whether this perturbation leads to a significant alteration in CEBPG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor CEBPG expression. Decide whether this perturbation leads to a significant alteration in CEBPG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and ZMYND8 expression is observed. Does this perturbation lead to a significant difference in ZMYND8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and ZMYND8 expression is observed. Does this perturbation lead to a significant difference in ZMYND8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1523
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor PELO expression. Decide whether this perturbation leads to a significant alteration in PELO expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor PELO expression. Decide whether this perturbation leads to a significant alteration in PELO expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2118
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of ZFHX3. Does this perturbation cause a significant change in ZFHX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2094
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and NRIP1 expression is quantified. Does this perturbation result in a significant change in NRIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and NRIP1 expression is quantified. Does this perturbation result in a significant change in NRIP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3622
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and P4HB expression is quantified. Does this perturbation result in a significant change in P4HB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and P4HB expression is quantified. Does this perturbation result in a significant change in P4HB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4612
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor SNHG10 expression. Decide whether this perturbation leads to a significant alteration in SNHG10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor SNHG10 expression. Decide whether this perturbation leads to a significant alteration in SNHG10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1318
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and TAGLN expression is observed. Does this perturbation lead to a significant difference in TAGLN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and TAGLN expression is observed. Does this perturbation lead to a significant difference in TAGLN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1353
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and PELO expression is measured. Determine whether PELO exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and PELO expression is measured. Determine whether PELO exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2119
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of SP100 is measured. Does this perturbation cause a significant change in SP100 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of SP100 is measured. Does this perturbation cause a significant change in SP100 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1140
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and DKFZP779L1853 expression is measured. Determine whether DKFZP779L1853 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and DKFZP779L1853 expression is measured. Determine whether DKFZP779L1853 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2389
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and ATP6AP2 expression is quantified. Does this perturbation result in a significant change in ATP6AP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and ATP6AP2 expression is quantified. Does this perturbation result in a significant change in ATP6AP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1622
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of ADAMTS10 is measured. Determine whether ADAMTS10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of ADAMTS10 is measured. Determine whether ADAMTS10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1076
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in ZNF280B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in ZNF280B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1105
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and AC015987.1 expression is observed. Does this perturbation lead to a significant difference in AC015987.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and AC015987.1 expression is observed. Does this perturbation lead to a significant difference in AC015987.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2253
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of CENPC. Does perturbing DERL2 lead to a significant change in CENPC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of CENPC. Does perturbing DERL2 lead to a significant change in CENPC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2181
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and TMEM60 expression is measured. Determine whether TMEM60 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and TMEM60 expression is measured. Determine whether TMEM60 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3519
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of ACSM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of ACSM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2217
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and NCKAP1L expression is observed. Does this perturbation lead to a significant difference in NCKAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and NCKAP1L expression is observed. Does this perturbation lead to a significant difference in NCKAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":443
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of ACE. Does this perturbation cause a significant change in ACE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of ACE. Does this perturbation cause a significant change in ACE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2574
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and ATF7IP2 expression is measured. Determine whether ATF7IP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and ATF7IP2 expression is measured. Determine whether ATF7IP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4529
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4432
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of C19orf59 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of C19orf59 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2347
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and CTD-2587M2.1 expression is measured. Determine whether CTD-2587M2.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and CTD-2587M2.1 expression is measured. Determine whether CTD-2587M2.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1919
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and WDR72 expression is quantified. Does this perturbation result in a significant change in WDR72 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and WDR72 expression is quantified. Does this perturbation result in a significant change in WDR72 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4132
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of DDX6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of DDX6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":527
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of RP11-90P5.2. Does perturbing EIF2B4 lead to a significant change in RP11-90P5.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of RP11-90P5.2. Does perturbing EIF2B4 lead to a significant change in RP11-90P5.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":401
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of TRAPPC10 is measured. Does this perturbation cause a significant change in TRAPPC10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of TRAPPC10 is measured. Does this perturbation cause a significant change in TRAPPC10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1850
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of HIST1H1D. Does perturbing SRPRB lead to a significant change in HIST1H1D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of HIST1H1D. Does perturbing SRPRB lead to a significant change in HIST1H1D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4341
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and AFF1 expression is quantified. Does this perturbation result in a significant change in AFF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and AFF1 expression is quantified. Does this perturbation result in a significant change in AFF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2912
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of CYP17A1-AS1. Does perturbing DDRGK1 lead to a significant change in CYP17A1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of CYP17A1-AS1. Does perturbing DDRGK1 lead to a significant change in CYP17A1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1241
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and PDE9A expression is observed. Does this perturbation lead to a significant difference in PDE9A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and PDE9A expression is observed. Does this perturbation lead to a significant difference in PDE9A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":193
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor NRIP1 expression. Decide whether this perturbation leads to a significant alteration in NRIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor NRIP1 expression. Decide whether this perturbation leads to a significant alteration in NRIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":128
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and ATP5EP2 expression is measured. Determine whether ATP5EP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and ATP5EP2 expression is measured. Determine whether ATP5EP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2959
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of H1FX. Does this perturbation cause a significant change in H1FX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of H1FX. Does this perturbation cause a significant change in H1FX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4674
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and HM13 expression is measured. Determine whether HM13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and HM13 expression is measured. Determine whether HM13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4519
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of DYNC1H1. Does this perturbation cause a significant change in DYNC1H1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of DYNC1H1. Does this perturbation cause a significant change in DYNC1H1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3144
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of STARD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of STARD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4607
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor PCF11 expression. Decide whether this perturbation leads to a significant alteration in PCF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor PCF11 expression. Decide whether this perturbation leads to a significant alteration in PCF11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":548
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of RP11-16E12.1 is measured. Does this perturbation cause a significant change in RP11-16E12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of RP11-16E12.1 is measured. Does this perturbation cause a significant change in RP11-16E12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3230
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor SRP72 expression. Decide whether this perturbation leads to a significant alteration in SRP72 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor SRP72 expression. Decide whether this perturbation leads to a significant alteration in SRP72 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1238
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in TOPBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in TOPBP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3805
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of NTRK1 is measured. Determine whether NTRK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of NTRK1 is measured. Determine whether NTRK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4036
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of TRIM38 is measured. Does this perturbation cause a significant change in TRIM38 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of TRIM38 is measured. Does this perturbation cause a significant change in TRIM38 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3380
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and AC096559.1 expression is measured. Determine whether AC096559.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and AC096559.1 expression is measured. Determine whether AC096559.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1879
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of SLBP. Does perturbing SLC39A7 lead to a significant change in SLBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of SLBP. Does perturbing SLC39A7 lead to a significant change in SLBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2131
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of RP11-471M2.3 is measured. Does this perturbation cause a significant change in RP11-471M2.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of RP11-471M2.3 is measured. Does this perturbation cause a significant change in RP11-471M2.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2590
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of MT2A is measured. Determine whether MT2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of MT2A is measured. Determine whether MT2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3166
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in PELO expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in PELO expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3985
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor TUBA1C expression. Decide whether this perturbation leads to a significant alteration in TUBA1C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor TUBA1C expression. Decide whether this perturbation leads to a significant alteration in TUBA1C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3398
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor KLF3 expression. Decide whether this perturbation leads to a significant alteration in KLF3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor KLF3 expression. Decide whether this perturbation leads to a significant alteration in KLF3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1988
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of ACSM3. Does this perturbation cause a significant change in ACSM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of ACSM3. Does this perturbation cause a significant change in ACSM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2214
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of LIMS1 is measured. Does this perturbation cause a significant change in LIMS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of LIMS1 is measured. Does this perturbation cause a significant change in LIMS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3370
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and SEPT5 expression is observed. Does this perturbation lead to a significant difference in SEPT5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and SEPT5 expression is observed. Does this perturbation lead to a significant difference in SEPT5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3543
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of SIGLEC6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of SIGLEC6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3347
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and HLTF expression is measured. Determine whether HLTF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and HLTF expression is measured. Determine whether HLTF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2489
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of ZMYND8 is measured. Determine whether ZMYND8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of ZMYND8 is measured. Determine whether ZMYND8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1526
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in KIAA1432 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in KIAA1432 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3755
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and CTD-2267D19.3 expression is observed. Does this perturbation lead to a significant difference in CTD-2267D19.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and CTD-2267D19.3 expression is observed. Does this perturbation lead to a significant difference in CTD-2267D19.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1543
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in APOL4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in APOL4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":895
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and MANF expression is observed. Does this perturbation lead to a significant difference in MANF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and MANF expression is observed. Does this perturbation lead to a significant difference in MANF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2413
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of NPDC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of NPDC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1327
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and C12orf23 expression is quantified. Does this perturbation result in a significant change in C12orf23 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and C12orf23 expression is quantified. Does this perturbation result in a significant change in C12orf23 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1762
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of ZFHX3. Does perturbing TTI2 lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of ZFHX3. Does perturbing TTI2 lead to a significant change in ZFHX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2091
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and SEC23IP expression is observed. Does this perturbation lead to a significant difference in SEC23IP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and SEC23IP expression is observed. Does this perturbation lead to a significant difference in SEC23IP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3973
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor TSC22D4 expression. Decide whether this perturbation leads to a significant alteration in TSC22D4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor TSC22D4 expression. Decide whether this perturbation leads to a significant alteration in TSC22D4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3278
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and NTRK1 expression is observed. Does this perturbation lead to a significant difference in NTRK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and NTRK1 expression is observed. Does this perturbation lead to a significant difference in NTRK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4033
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of H1FX is measured. Determine whether H1FX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of H1FX is measured. Determine whether H1FX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4676
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of SAMM50. Does this perturbation cause a significant change in SAMM50 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of SAMM50. Does this perturbation cause a significant change in SAMM50 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":624
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and TAP1 expression is quantified. Does this perturbation result in a significant change in TAP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and TAP1 expression is quantified. Does this perturbation result in a significant change in TAP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4712
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of TRIM38 is measured. Determine whether TRIM38 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of TRIM38 is measured. Determine whether TRIM38 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3386
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and TGOLN2 expression is measured. Determine whether TGOLN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and TGOLN2 expression is measured. Determine whether TGOLN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5099
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of FGF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of FGF11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4177
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of LBX1. Does this perturbation cause a significant change in LBX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of LBX1. Does this perturbation cause a significant change in LBX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1594
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and GOT1 expression is measured. Determine whether GOT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and GOT1 expression is measured. Determine whether GOT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1119
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor SAMM50 expression. Decide whether this perturbation leads to a significant alteration in SAMM50 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor SAMM50 expression. Decide whether this perturbation leads to a significant alteration in SAMM50 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":628
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of IL18R1 is measured. Does this perturbation cause a significant change in IL18R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of IL18R1 is measured. Does this perturbation cause a significant change in IL18R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4200
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor GATA3 expression. Decide whether this perturbation leads to a significant alteration in GATA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor GATA3 expression. Decide whether this perturbation leads to a significant alteration in GATA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":888
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and DYNC1H1 expression is measured. Determine whether DYNC1H1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and DYNC1H1 expression is measured. Determine whether DYNC1H1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3149
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of VIMP. Does this perturbation cause a significant change in VIMP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of VIMP. Does this perturbation cause a significant change in VIMP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4584
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of CTC-308K20.1. Does this perturbation cause a significant change in CTC-308K20.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of CTC-308K20.1. Does this perturbation cause a significant change in CTC-308K20.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5134
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in TLK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in TLK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1995
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of SNRNP25. Does perturbing SLC39A7 lead to a significant change in SNRNP25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of SNRNP25. Does perturbing SLC39A7 lead to a significant change in SNRNP25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2151
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor HM13 expression. Decide whether this perturbation leads to a significant alteration in HM13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor HM13 expression. Decide whether this perturbation leads to a significant alteration in HM13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4518
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and TOB2 expression is measured. Determine whether TOB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and TOB2 expression is measured. Determine whether TOB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":989
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of CPQ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of CPQ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2967
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of ARHGAP30. Does perturbing MRGBP lead to a significant change in ARHGAP30 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of ARHGAP30. Does perturbing MRGBP lead to a significant change in ARHGAP30 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1471
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of GRN is measured. Does this perturbation cause a significant change in GRN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of GRN is measured. Does this perturbation cause a significant change in GRN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4330
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of RP11-247A12.2. Does perturbing ATP5B lead to a significant change in RP11-247A12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of RP11-247A12.2. Does perturbing ATP5B lead to a significant change in RP11-247A12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1661
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and EXOC3L2 expression is measured. Determine whether EXOC3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and EXOC3L2 expression is measured. Determine whether EXOC3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3359
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and ANKLE2 expression is quantified. Does this perturbation result in a significant change in ANKLE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and ANKLE2 expression is quantified. Does this perturbation result in a significant change in ANKLE2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2312
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of CFH is measured. Determine whether CFH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of CFH is measured. Determine whether CFH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5056
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in RP11-24F11.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in RP11-24F11.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1495
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of SNHG10. Does perturbing CAD lead to a significant change in SNHG10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of SNHG10. Does perturbing CAD lead to a significant change in SNHG10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1881
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of NOXA1. Does perturbing SAMM50 lead to a significant change in NOXA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of NOXA1. Does perturbing SAMM50 lead to a significant change in NOXA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1411
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3506
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and KIAA1731 expression is measured. Determine whether KIAA1731 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and KIAA1731 expression is measured. Determine whether KIAA1731 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4899
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2306
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and POU2F2 expression is quantified. Does this perturbation result in a significant change in POU2F2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and POU2F2 expression is quantified. Does this perturbation result in a significant change in POU2F2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":652
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor RSAD2 expression. Decide whether this perturbation leads to a significant alteration in RSAD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor RSAD2 expression. Decide whether this perturbation leads to a significant alteration in RSAD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4408
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and RP11-247A12.2 expression is measured. Determine whether RP11-247A12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and RP11-247A12.2 expression is measured. Determine whether RP11-247A12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1669
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor JUND expression. Decide whether this perturbation leads to a significant alteration in JUND expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor JUND expression. Decide whether this perturbation leads to a significant alteration in JUND expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":778
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PHF19 expression is measured. Determine whether PHF19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PHF19 expression is measured. Determine whether PHF19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3069
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of H1FX. Does perturbing EIF2B3 lead to a significant change in H1FX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of H1FX. Does perturbing EIF2B3 lead to a significant change in H1FX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4671
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and RP11-471M2.3 expression is quantified. Does this perturbation result in a significant change in RP11-471M2.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and RP11-471M2.3 expression is quantified. Does this perturbation result in a significant change in RP11-471M2.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2592
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and GDF11 expression is observed. Does this perturbation lead to a significant difference in GDF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and GDF11 expression is observed. Does this perturbation lead to a significant difference in GDF11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":393
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and VAMP2 expression is observed. Does this perturbation lead to a significant difference in VAMP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and VAMP2 expression is observed. Does this perturbation lead to a significant difference in VAMP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2903
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and FGF11 expression is measured. Determine whether FGF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and FGF11 expression is measured. Determine whether FGF11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4179
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor PTBP3 expression. Decide whether this perturbation leads to a significant alteration in PTBP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor PTBP3 expression. Decide whether this perturbation leads to a significant alteration in PTBP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":668
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of CHST12. Does perturbing KCTD16 lead to a significant change in CHST12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of CHST12. Does perturbing KCTD16 lead to a significant change in CHST12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3461
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in SBF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in SBF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2565
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor BAMBI expression. Decide whether this perturbation leads to a significant alteration in BAMBI expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor BAMBI expression. Decide whether this perturbation leads to a significant alteration in BAMBI expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1278
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor AFF1 expression. Decide whether this perturbation leads to a significant alteration in AFF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor AFF1 expression. Decide whether this perturbation leads to a significant alteration in AFF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2918
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and HIST1H1E expression is observed. Does this perturbation lead to a significant difference in HIST1H1E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and HIST1H1E expression is observed. Does this perturbation lead to a significant difference in HIST1H1E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1023
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1952
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor SP100 expression. Decide whether this perturbation leads to a significant alteration in SP100 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor SP100 expression. Decide whether this perturbation leads to a significant alteration in SP100 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1148
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor H3F3B expression. Decide whether this perturbation leads to a significant alteration in H3F3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor H3F3B expression. Decide whether this perturbation leads to a significant alteration in H3F3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2328
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in ABI2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in ABI2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2025
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of DNASE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of DNASE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1637
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of KCNQ1OT1 is measured. Determine whether KCNQ1OT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of KCNQ1OT1 is measured. Determine whether KCNQ1OT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4626
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and ERV3-1 expression is measured. Determine whether ERV3-1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and ERV3-1 expression is measured. Determine whether ERV3-1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":469
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of EPS15. Does perturbing XRN1 lead to a significant change in EPS15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of EPS15. Does perturbing XRN1 lead to a significant change in EPS15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4841
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in GOT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in GOT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1115
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in C3AR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in C3AR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3405
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2043
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and NRIP1 expression is observed. Does this perturbation lead to a significant difference in NRIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and NRIP1 expression is observed. Does this perturbation lead to a significant difference in NRIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":123
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and PBDC1 expression is quantified. Does this perturbation result in a significant change in PBDC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and PBDC1 expression is quantified. Does this perturbation result in a significant change in PBDC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":602
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and SSBP2 expression is observed. Does this perturbation lead to a significant difference in SSBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and SSBP2 expression is observed. Does this perturbation lead to a significant difference in SSBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4163
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in NPDC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in NPDC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1325
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of KCTD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of KCTD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1377
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and NSD1 expression is measured. Determine whether NSD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and NSD1 expression is measured. Determine whether NSD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1349
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of CCRL2 is measured. Does this perturbation cause a significant change in CCRL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of CCRL2 is measured. Does this perturbation cause a significant change in CCRL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3550
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor ZNF280B expression. Decide whether this perturbation leads to a significant alteration in ZNF280B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor ZNF280B expression. Decide whether this perturbation leads to a significant alteration in ZNF280B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1108
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of ZC3H7A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of ZC3H7A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3677
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and BAMBI expression is observed. Does this perturbation lead to a significant difference in BAMBI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and BAMBI expression is observed. Does this perturbation lead to a significant difference in BAMBI expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1273
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and RP11-227G15.8 expression is measured. Determine whether RP11-227G15.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and RP11-227G15.8 expression is measured. Determine whether RP11-227G15.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2939
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of EXO1 is measured. Does this perturbation cause a significant change in EXO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of EXO1 is measured. Does this perturbation cause a significant change in EXO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2830
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ARHGAP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ARHGAP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3905
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of GS1-166A23.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of GS1-166A23.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3297
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor P4HA2 expression. Decide whether this perturbation leads to a significant alteration in P4HA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor P4HA2 expression. Decide whether this perturbation leads to a significant alteration in P4HA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and C10orf32 expression is quantified. Does this perturbation result in a significant change in C10orf32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and C10orf32 expression is quantified. Does this perturbation result in a significant change in C10orf32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3042
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of CTD-2001C12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of CTD-2001C12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":577
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of JUND indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of JUND indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":777
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of ATXN7L3B is measured. Determine whether ATXN7L3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of ATXN7L3B is measured. Determine whether ATXN7L3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4936
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor S100A11 expression. Decide whether this perturbation leads to a significant alteration in S100A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor S100A11 expression. Decide whether this perturbation leads to a significant alteration in S100A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4648
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of EP300 is measured. Determine whether EP300 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of EP300 is measured. Determine whether EP300 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1686
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in CD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in CD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":425
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of GPRC5C. Does this perturbation cause a significant change in GPRC5C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of GPRC5C. Does this perturbation cause a significant change in GPRC5C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2224
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor RP11-838N2.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-838N2.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor RP11-838N2.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-838N2.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3038
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3962
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of PAK1IP1. Does this perturbation cause a significant change in PAK1IP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of PAK1IP1. Does this perturbation cause a significant change in PAK1IP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4254
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor ZEB1 expression. Decide whether this perturbation leads to a significant alteration in ZEB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor ZEB1 expression. Decide whether this perturbation leads to a significant alteration in ZEB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1388
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in IL2RB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in IL2RB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3605
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and KIAA1432 expression is quantified. Does this perturbation result in a significant change in KIAA1432 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and KIAA1432 expression is quantified. Does this perturbation result in a significant change in KIAA1432 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3752
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of RTN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of RTN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2067
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and RBM12B-AS1 expression is measured. Determine whether RBM12B-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and RBM12B-AS1 expression is measured. Determine whether RBM12B-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2519
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of DNMBP is measured. Does this perturbation cause a significant change in DNMBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of DNMBP is measured. Does this perturbation cause a significant change in DNMBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4010
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and MT2A expression is quantified. Does this perturbation result in a significant change in MT2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and MT2A expression is quantified. Does this perturbation result in a significant change in MT2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3162
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and HIST1H2AM expression is observed. Does this perturbation lead to a significant difference in HIST1H2AM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and HIST1H2AM expression is observed. Does this perturbation lead to a significant difference in HIST1H2AM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":383
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of BOLA3 is measured. Determine whether BOLA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of BOLA3 is measured. Determine whether BOLA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4636
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor HLTF expression. Decide whether this perturbation leads to a significant alteration in HLTF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor HLTF expression. Decide whether this perturbation leads to a significant alteration in HLTF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2488
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor SLC25A35 expression. Decide whether this perturbation leads to a significant alteration in SLC25A35 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor SLC25A35 expression. Decide whether this perturbation leads to a significant alteration in SLC25A35 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3158
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of TNFRSF10B is measured. Does this perturbation cause a significant change in TNFRSF10B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of TNFRSF10B is measured. Does this perturbation cause a significant change in TNFRSF10B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3860
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in ANXA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in ANXA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":745
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and RGS20 expression is observed. Does this perturbation lead to a significant difference in RGS20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and RGS20 expression is observed. Does this perturbation lead to a significant difference in RGS20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3123
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of SPAST. Does perturbing DARS lead to a significant change in SPAST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of SPAST. Does perturbing DARS lead to a significant change in SPAST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":921
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and GMEB1 expression is observed. Does this perturbation lead to a significant difference in GMEB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and GMEB1 expression is observed. Does this perturbation lead to a significant difference in GMEB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1203
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of LRRC4B is measured. Determine whether LRRC4B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of LRRC4B is measured. Determine whether LRRC4B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2176
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of LBX1 is measured. Does this perturbation cause a significant change in LBX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of LBX1 is measured. Does this perturbation cause a significant change in LBX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1590
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in DOCK8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in DOCK8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1565
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor VIM-AS1 expression. Decide whether this perturbation leads to a significant alteration in VIM-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor VIM-AS1 expression. Decide whether this perturbation leads to a significant alteration in VIM-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1728
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2122
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of H3F3B is measured. Determine whether H3F3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of H3F3B is measured. Determine whether H3F3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2326
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and EGLN3 expression is measured. Determine whether EGLN3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and EGLN3 expression is measured. Determine whether EGLN3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3319
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of ZNF789 is measured. Determine whether ZNF789 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of ZNF789 is measured. Determine whether ZNF789 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3226
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of LPAR5 is measured. Determine whether LPAR5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of LPAR5 is measured. Determine whether LPAR5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and GUSB expression is observed. Does this perturbation lead to a significant difference in GUSB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and GUSB expression is observed. Does this perturbation lead to a significant difference in GUSB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1403
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in HIST1H2AC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in HIST1H2AC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3025
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of RP11-445H22.3 is measured. Determine whether RP11-445H22.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of RP11-445H22.3 is measured. Determine whether RP11-445H22.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3816
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in LBX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in LBX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1595
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor KCTD1 expression. Decide whether this perturbation leads to a significant alteration in KCTD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor KCTD1 expression. Decide whether this perturbation leads to a significant alteration in KCTD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1378
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of ATP11B is measured. Does this perturbation cause a significant change in ATP11B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of ATP11B is measured. Does this perturbation cause a significant change in ATP11B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":290
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and ZEB1 expression is observed. Does this perturbation lead to a significant difference in ZEB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and ZEB1 expression is observed. Does this perturbation lead to a significant difference in ZEB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1383
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of WHSC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of WHSC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1487
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and RP11-38P22.2 expression is measured. Determine whether RP11-38P22.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and RP11-38P22.2 expression is measured. Determine whether RP11-38P22.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1059
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of KANSL1L. Does this perturbation cause a significant change in KANSL1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of KANSL1L. Does this perturbation cause a significant change in KANSL1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":644
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and CHD3 expression is measured. Determine whether CHD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and CHD3 expression is measured. Determine whether CHD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4909
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of FCGR2A. Does perturbing TTI2 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of FCGR2A. Does perturbing TTI2 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2041
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of CENPF is measured. Does this perturbation cause a significant change in CENPF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of CENPF is measured. Does this perturbation cause a significant change in CENPF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4060
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of CST7 is measured. Determine whether CST7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of CST7 is measured. Determine whether CST7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2206
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and OPTN expression is observed. Does this perturbation lead to a significant difference in OPTN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and OPTN expression is observed. Does this perturbation lead to a significant difference in OPTN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":553
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of ATAD2B is measured. Determine whether ATAD2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of ATAD2B is measured. Determine whether ATAD2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4396
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and ATF6 expression is measured. Determine whether ATF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and ATF6 expression is measured. Determine whether ATF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":859
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor CHST12 expression. Decide whether this perturbation leads to a significant alteration in CHST12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor CHST12 expression. Decide whether this perturbation leads to a significant alteration in CHST12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3468
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor GPRC5C expression. Decide whether this perturbation leads to a significant alteration in GPRC5C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor GPRC5C expression. Decide whether this perturbation leads to a significant alteration in GPRC5C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2228
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and PTPRC expression is measured. Determine whether PTPRC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and PTPRC expression is measured. Determine whether PTPRC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":239
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of C12orf23. Does this perturbation cause a significant change in C12orf23 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of C12orf23. Does this perturbation cause a significant change in C12orf23 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1764
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of ATXN7L3B. Does this perturbation cause a significant change in ATXN7L3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of ATXN7L3B. Does this perturbation cause a significant change in ATXN7L3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4934
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of ATF7IP2 is measured. Determine whether ATF7IP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of ATF7IP2 is measured. Determine whether ATF7IP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4526
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and VIM-AS1 expression is quantified. Does this perturbation result in a significant change in VIM-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and VIM-AS1 expression is quantified. Does this perturbation result in a significant change in VIM-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1722
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of FAM114A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of FAM114A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":717
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of GATA3. Does perturbing AMIGO3 lead to a significant change in GATA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of GATA3. Does perturbing AMIGO3 lead to a significant change in GATA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":881
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of NOSTRIN. Does perturbing SRPRB lead to a significant change in NOSTRIN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of NOSTRIN. Does perturbing SRPRB lead to a significant change in NOSTRIN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4321
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of RCBTB2 is measured. Does this perturbation cause a significant change in RCBTB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of RCBTB2 is measured. Does this perturbation cause a significant change in RCBTB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1330
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and PELO expression is observed. Does this perturbation lead to a significant difference in PELO expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and PELO expression is observed. Does this perturbation lead to a significant difference in PELO expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3983
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in MORC2-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in MORC2-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2555
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of NRIP1. Does this perturbation cause a significant change in NRIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of NRIP1. Does this perturbation cause a significant change in NRIP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3624
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of NINJ2. Does this perturbation cause a significant change in NINJ2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of NINJ2. Does this perturbation cause a significant change in NINJ2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2144
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of TNFRSF10B is measured. Does this perturbation cause a significant change in TNFRSF10B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of TNFRSF10B is measured. Does this perturbation cause a significant change in TNFRSF10B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2280
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of DST. Does this perturbation cause a significant change in DST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of DST. Does this perturbation cause a significant change in DST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3494
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of MANF is measured. Determine whether MANF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of MANF is measured. Determine whether MANF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2416
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and IL32 expression is observed. Does this perturbation lead to a significant difference in IL32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and IL32 expression is observed. Does this perturbation lead to a significant difference in IL32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":563
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of BACH2. Does this perturbation cause a significant change in BACH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of BACH2. Does this perturbation cause a significant change in BACH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3474
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor SEPT5 expression. Decide whether this perturbation leads to a significant alteration in SEPT5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor SEPT5 expression. Decide whether this perturbation leads to a significant alteration in SEPT5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3548
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and HIST1H3D expression is quantified. Does this perturbation result in a significant change in HIST1H3D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and HIST1H3D expression is quantified. Does this perturbation result in a significant change in HIST1H3D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":912
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor RP11-322J23.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-322J23.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor RP11-322J23.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-322J23.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4728
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of PHF3. Does perturbing ZNF326 lead to a significant change in PHF3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of PHF3. Does perturbing ZNF326 lead to a significant change in PHF3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of RP11-247A12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of RP11-247A12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1667
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of SERPINF2 is measured. Determine whether SERPINF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of SERPINF2 is measured. Determine whether SERPINF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3956
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of NFAT5 is measured. Determine whether NFAT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of NFAT5 is measured. Determine whether NFAT5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1816
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and IRF7 expression is observed. Does this perturbation lead to a significant difference in IRF7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and IRF7 expression is observed. Does this perturbation lead to a significant difference in IRF7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":533
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of NRIP1 is measured. Determine whether NRIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of NRIP1 is measured. Determine whether NRIP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":126
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and GATA3 expression is observed. Does this perturbation lead to a significant difference in GATA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and GATA3 expression is observed. Does this perturbation lead to a significant difference in GATA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":883
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of C12orf23 is measured. Does this perturbation cause a significant change in C12orf23 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of C12orf23 is measured. Does this perturbation cause a significant change in C12orf23 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1760
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of TLK2 is measured. Determine whether TLK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of TLK2 is measured. Determine whether TLK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1996
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of ACSM3 is measured. Does this perturbation cause a significant change in ACSM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of ACSM3 is measured. Does this perturbation cause a significant change in ACSM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2210
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of FAM114A1. Does perturbing SLMO2 lead to a significant change in FAM114A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of FAM114A1. Does perturbing SLMO2 lead to a significant change in FAM114A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":711
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of KDM1B. Does perturbing UFL1 lead to a significant change in KDM1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of KDM1B. Does perturbing UFL1 lead to a significant change in KDM1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1161
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of PRRC2B is measured. Determine whether PRRC2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of PRRC2B is measured. Determine whether PRRC2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":906
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and TKTL1 expression is quantified. Does this perturbation result in a significant change in TKTL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and TKTL1 expression is quantified. Does this perturbation result in a significant change in TKTL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":172
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in RP11-573D15.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in RP11-573D15.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3885
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor IL13RA1 expression. Decide whether this perturbation leads to a significant alteration in IL13RA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor IL13RA1 expression. Decide whether this perturbation leads to a significant alteration in IL13RA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2358
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of IFNGR1. Does perturbing MANF lead to a significant change in IFNGR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of IFNGR1. Does perturbing MANF lead to a significant change in IFNGR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2651
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and RP11-227G15.8 expression is observed. Does this perturbation lead to a significant difference in RP11-227G15.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and RP11-227G15.8 expression is observed. Does this perturbation lead to a significant difference in RP11-227G15.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2933
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and REST expression is measured. Determine whether REST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and REST expression is measured. Determine whether REST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":799
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in RNF19A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in RNF19A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3765
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of LAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of LAMP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2777
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of CTD-2267D19.3. Does this perturbation cause a significant change in CTD-2267D19.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of CTD-2267D19.3. Does this perturbation cause a significant change in CTD-2267D19.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1544
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in NINJ2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in NINJ2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2145
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and QSER1 expression is quantified. Does this perturbation result in a significant change in QSER1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and QSER1 expression is quantified. Does this perturbation result in a significant change in QSER1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3002
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of ZNF292 is measured. Determine whether ZNF292 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of ZNF292 is measured. Determine whether ZNF292 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3566
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor ATP2A3 expression. Decide whether this perturbation leads to a significant alteration in ATP2A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor ATP2A3 expression. Decide whether this perturbation leads to a significant alteration in ATP2A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1838
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and CENPC expression is quantified. Does this perturbation result in a significant change in CENPC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and CENPC expression is quantified. Does this perturbation result in a significant change in CENPC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2182
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor HIST1H2AC expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor HIST1H2AC expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3028
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of PPP1R16B. Does this perturbation cause a significant change in PPP1R16B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of PPP1R16B. Does this perturbation cause a significant change in PPP1R16B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":594
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and LAMP2 expression is measured. Determine whether LAMP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and LAMP2 expression is measured. Determine whether LAMP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2779
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of CEBPG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of CEBPG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of CPQ is measured. Determine whether CPQ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of CPQ is measured. Determine whether CPQ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2966
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and TRPM4 expression is measured. Determine whether TRPM4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and TRPM4 expression is measured. Determine whether TRPM4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3849
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of TAGLN. Does perturbing STT3A lead to a significant change in TAGLN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of TAGLN. Does perturbing STT3A lead to a significant change in TAGLN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1351
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in TACC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in TACC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1865
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of BAMBI is measured. Determine whether BAMBI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of BAMBI is measured. Determine whether BAMBI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1276
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of NXF1 is measured. Determine whether NXF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of NXF1 is measured. Determine whether NXF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3116
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of RP11-789C1.1. Does perturbing DARS lead to a significant change in RP11-789C1.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of RP11-789C1.1. Does perturbing DARS lead to a significant change in RP11-789C1.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":941
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of CDCA3 is measured. Does this perturbation cause a significant change in CDCA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of CDCA3 is measured. Does this perturbation cause a significant change in CDCA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4110
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2536
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of QSER1 is measured. Determine whether QSER1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of QSER1 is measured. Determine whether QSER1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3006
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor SMIM14 expression. Decide whether this perturbation leads to a significant alteration in SMIM14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor SMIM14 expression. Decide whether this perturbation leads to a significant alteration in SMIM14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3308
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4757
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and CTC-308K20.1 expression is quantified. Does this perturbation result in a significant change in CTC-308K20.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and CTC-308K20.1 expression is quantified. Does this perturbation result in a significant change in CTC-308K20.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5132
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of GALNT7. Does this perturbation cause a significant change in GALNT7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of GALNT7. Does this perturbation cause a significant change in GALNT7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4384
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in LTN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in LTN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3785
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and ZNF292 expression is measured. Determine whether ZNF292 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and ZNF292 expression is measured. Determine whether ZNF292 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1509
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of C9orf64. Does this perturbation cause a significant change in C9orf64 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of C9orf64. Does this perturbation cause a significant change in C9orf64 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3874
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and USP34 expression is observed. Does this perturbation lead to a significant difference in USP34 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and USP34 expression is observed. Does this perturbation lead to a significant difference in USP34 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4363
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and LAMP2 expression is observed. Does this perturbation lead to a significant difference in LAMP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and LAMP2 expression is observed. Does this perturbation lead to a significant difference in LAMP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2773
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in DSC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in DSC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4095
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and EPS15 expression is measured. Determine whether EPS15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and EPS15 expression is measured. Determine whether EPS15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4849
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RP11-141B14.1 expression is observed. Does this perturbation lead to a significant difference in RP11-141B14.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RP11-141B14.1 expression is observed. Does this perturbation lead to a significant difference in RP11-141B14.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and NRIP1 expression is observed. Does this perturbation lead to a significant difference in NRIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and NRIP1 expression is observed. Does this perturbation lead to a significant difference in NRIP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3623
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of ITGB2. Does this perturbation cause a significant change in ITGB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of ITGB2. Does this perturbation cause a significant change in ITGB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1304
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and LTN1 expression is observed. Does this perturbation lead to a significant difference in LTN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and LTN1 expression is observed. Does this perturbation lead to a significant difference in LTN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3783
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and GUSB expression is observed. Does this perturbation lead to a significant difference in GUSB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and GUSB expression is observed. Does this perturbation lead to a significant difference in GUSB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1933
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of RNF8. Does perturbing TTI1 lead to a significant change in RNF8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of RNF8. Does perturbing TTI1 lead to a significant change in RNF8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3181
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor LINC00862 expression. Decide whether this perturbation leads to a significant alteration in LINC00862 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor LINC00862 expression. Decide whether this perturbation leads to a significant alteration in LINC00862 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4598
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and SLC27A2 expression is observed. Does this perturbation lead to a significant difference in SLC27A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and SLC27A2 expression is observed. Does this perturbation lead to a significant difference in SLC27A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3683
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and RP13-216E22.4 expression is measured. Determine whether RP13-216E22.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and RP13-216E22.4 expression is measured. Determine whether RP13-216E22.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2439
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and ZC3H7A expression is observed. Does this perturbation lead to a significant difference in ZC3H7A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and ZC3H7A expression is observed. Does this perturbation lead to a significant difference in ZC3H7A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3673
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RGS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of RGS20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2717
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and HIST1H1E expression is measured. Determine whether HIST1H1E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and HIST1H1E expression is measured. Determine whether HIST1H1E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1029
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in HOTAIRM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in HOTAIRM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1265
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor TSNAXIP1 expression. Decide whether this perturbation leads to a significant alteration in TSNAXIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor TSNAXIP1 expression. Decide whether this perturbation leads to a significant alteration in TSNAXIP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":758
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of DOCK11. Does perturbing EIF2B4 lead to a significant change in DOCK11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of DOCK11. Does perturbing EIF2B4 lead to a significant change in DOCK11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":361
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and FGF11 expression is quantified. Does this perturbation result in a significant change in FGF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and FGF11 expression is quantified. Does this perturbation result in a significant change in FGF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4172
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in PPP4R2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in PPP4R2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2375
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of RP11-90P5.2. Does this perturbation cause a significant change in RP11-90P5.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of RP11-90P5.2. Does this perturbation cause a significant change in RP11-90P5.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":404
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and UHMK1 expression is observed. Does this perturbation lead to a significant difference in UHMK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and UHMK1 expression is observed. Does this perturbation lead to a significant difference in UHMK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4983
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor RP11-381O7.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-381O7.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor RP11-381O7.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-381O7.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1558
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of RP11-247A12.2 is measured. Determine whether RP11-247A12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of RP11-247A12.2 is measured. Determine whether RP11-247A12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1666
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of TMEM60 is measured. Does this perturbation cause a significant change in TMEM60 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of TMEM60 is measured. Does this perturbation cause a significant change in TMEM60 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3510
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and LAMP2 expression is quantified. Does this perturbation result in a significant change in LAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and LAMP2 expression is quantified. Does this perturbation result in a significant change in LAMP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5042
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and KDM1B expression is quantified. Does this perturbation result in a significant change in KDM1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and KDM1B expression is quantified. Does this perturbation result in a significant change in KDM1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1162
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and KLF3 expression is measured. Determine whether KLF3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and KLF3 expression is measured. Determine whether KLF3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1989
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of TFPI. Does perturbing SLC35B1 lead to a significant change in TFPI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of TFPI. Does perturbing SLC35B1 lead to a significant change in TFPI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3911
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of TAGLN is measured. Does this perturbation cause a significant change in TAGLN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of TAGLN is measured. Does this perturbation cause a significant change in TAGLN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1350
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of RP11-61E11.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of RP11-61E11.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1427
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of ANKRD10. Does perturbing SRPRB lead to a significant change in ANKRD10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of ANKRD10. Does perturbing SRPRB lead to a significant change in ANKRD10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4351
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and PARP11 expression is measured. Determine whether PARP11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and PARP11 expression is measured. Determine whether PARP11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3709
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and KIF4A expression is observed. Does this perturbation lead to a significant difference in KIF4A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and KIF4A expression is observed. Does this perturbation lead to a significant difference in KIF4A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2583
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of ATP11B. Does this perturbation cause a significant change in ATP11B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of ATP11B. Does this perturbation cause a significant change in ATP11B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":294
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of CTCFL is measured. Does this perturbation cause a significant change in CTCFL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of CTCFL is measured. Does this perturbation cause a significant change in CTCFL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2600
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of RP11-90P5.2 is measured. Does this perturbation cause a significant change in RP11-90P5.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of RP11-90P5.2 is measured. Does this perturbation cause a significant change in RP11-90P5.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":400
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of ANKLE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of ANKLE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2317
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of KIF4A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of KIF4A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2587
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in OXLD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in OXLD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2855
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and IFNGR1 expression is quantified. Does this perturbation result in a significant change in IFNGR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and IFNGR1 expression is quantified. Does this perturbation result in a significant change in IFNGR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2652
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of LTB. Does this perturbation cause a significant change in LTB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of LTB. Does this perturbation cause a significant change in LTB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4704
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of WDR3 is measured. Determine whether WDR3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of WDR3 is measured. Determine whether WDR3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4566
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor PHF3 expression. Decide whether this perturbation leads to a significant alteration in PHF3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor PHF3 expression. Decide whether this perturbation leads to a significant alteration in PHF3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2728
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of ZEB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of ZEB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":967
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor TOPBP1 expression. Decide whether this perturbation leads to a significant alteration in TOPBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor TOPBP1 expression. Decide whether this perturbation leads to a significant alteration in TOPBP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3808
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of RTN2 is measured. Determine whether RTN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of RTN2 is measured. Determine whether RTN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2066
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of PTPN11. Does perturbing IER3IP1 lead to a significant change in PTPN11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of PTPN11. Does perturbing IER3IP1 lead to a significant change in PTPN11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":501
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and VIMP expression is measured. Determine whether VIMP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and VIMP expression is measured. Determine whether VIMP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4589
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of NUFIP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of NUFIP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2467
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of APOL4. Does this perturbation cause a significant change in APOL4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of APOL4. Does this perturbation cause a significant change in APOL4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":894
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of CD58. Does perturbing GBF1 lead to a significant change in CD58 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of CD58. Does perturbing GBF1 lead to a significant change in CD58 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2491
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and POU2F2 expression is measured. Determine whether POU2F2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and POU2F2 expression is measured. Determine whether POU2F2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":659
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of TUBA1C. Does this perturbation cause a significant change in TUBA1C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of TUBA1C. Does this perturbation cause a significant change in TUBA1C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3394
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of TAP1. Does this perturbation cause a significant change in TAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of TAP1. Does this perturbation cause a significant change in TAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4714
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of C3AR1. Does this perturbation cause a significant change in C3AR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of C3AR1. Does this perturbation cause a significant change in C3AR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3404
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and IL8 expression is measured. Determine whether IL8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and IL8 expression is measured. Determine whether IL8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1259
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and LTB expression is quantified. Does this perturbation result in a significant change in LTB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and LTB expression is quantified. Does this perturbation result in a significant change in LTB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4702
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of PPP4R2. Does this perturbation cause a significant change in PPP4R2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of PPP4R2. Does this perturbation cause a significant change in PPP4R2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2374
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of ANXA4 is measured. Determine whether ANXA4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of ANXA4 is measured. Determine whether ANXA4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":746
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and ZC3H7A expression is measured. Determine whether ZC3H7A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and ZC3H7A expression is measured. Determine whether ZC3H7A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3679
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of EP300. Does perturbing SYVN1 lead to a significant change in EP300 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of EP300. Does perturbing SYVN1 lead to a significant change in EP300 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1681
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor PPP1R16B expression. Decide whether this perturbation leads to a significant alteration in PPP1R16B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor PPP1R16B expression. Decide whether this perturbation leads to a significant alteration in PPP1R16B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4488
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in GS1-166A23.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in GS1-166A23.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3295
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of WDR72 is measured. Determine whether WDR72 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of WDR72 is measured. Determine whether WDR72 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4136
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of SNHG10 is measured. Does this perturbation cause a significant change in SNHG10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of SNHG10 is measured. Does this perturbation cause a significant change in SNHG10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1310
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and HIST1H2AC expression is measured. Determine whether HIST1H2AC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and HIST1H2AC expression is measured. Determine whether HIST1H2AC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3029
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and CTBS expression is observed. Does this perturbation lead to a significant difference in CTBS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and CTBS expression is observed. Does this perturbation lead to a significant difference in CTBS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4443
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor RP11-90P5.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-90P5.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor RP11-90P5.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-90P5.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":408
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and SIGLEC6 expression is quantified. Does this perturbation result in a significant change in SIGLEC6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and SIGLEC6 expression is quantified. Does this perturbation result in a significant change in SIGLEC6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3342
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and FYTTD1 expression is quantified. Does this perturbation result in a significant change in FYTTD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and FYTTD1 expression is quantified. Does this perturbation result in a significant change in FYTTD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2362
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor DOK3 expression. Decide whether this perturbation leads to a significant alteration in DOK3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor DOK3 expression. Decide whether this perturbation leads to a significant alteration in DOK3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":268
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and RP11-499F3.2 expression is measured. Determine whether RP11-499F3.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and RP11-499F3.2 expression is measured. Determine whether RP11-499F3.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2889
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of ATP6V1B2 is measured. Determine whether ATP6V1B2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of ATP6V1B2 is measured. Determine whether ATP6V1B2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1606
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of ESCO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of ESCO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":867
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in ZCCHC11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in ZCCHC11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4995
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of OPTN. Does perturbing YIPF5 lead to a significant change in OPTN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of OPTN. Does perturbing YIPF5 lead to a significant change in OPTN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":551
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1699
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of ITGB2 is measured. Does this perturbation cause a significant change in ITGB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of ITGB2 is measured. Does this perturbation cause a significant change in ITGB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1300
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and PTGS1 expression is measured. Determine whether PTGS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and PTGS1 expression is measured. Determine whether PTGS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3489
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of HERC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of HERC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":957
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of ARHGDIB. Does perturbing TMEM167A lead to a significant change in ARHGDIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of ARHGDIB. Does perturbing TMEM167A lead to a significant change in ARHGDIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1961
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of RP11-132A1.4 is measured. Does this perturbation cause a significant change in RP11-132A1.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of RP11-132A1.4 is measured. Does this perturbation cause a significant change in RP11-132A1.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":720
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in TLK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in TLK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4765
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of RIMS3. Does this perturbation cause a significant change in RIMS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of RIMS3. Does this perturbation cause a significant change in RIMS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":164
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of C3AR1 is measured. Determine whether C3AR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of C3AR1 is measured. Determine whether C3AR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3406
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in ARHGDIB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in ARHGDIB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1965
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor ASPM expression. Decide whether this perturbation leads to a significant alteration in ASPM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor ASPM expression. Decide whether this perturbation leads to a significant alteration in ASPM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2668
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in IL18R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in IL18R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":355
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of DDX3X. Does this perturbation cause a significant change in DDX3X expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of DDX3X. Does this perturbation cause a significant change in DDX3X expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1084
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of KCNJ13 is measured. Does this perturbation cause a significant change in KCNJ13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of KCNJ13 is measured. Does this perturbation cause a significant change in KCNJ13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3650
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor MBNL1 expression. Decide whether this perturbation leads to a significant alteration in MBNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor MBNL1 expression. Decide whether this perturbation leads to a significant alteration in MBNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4818
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and HAGH expression is measured. Determine whether HAGH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and HAGH expression is measured. Determine whether HAGH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2639
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor CASP8 expression. Decide whether this perturbation leads to a significant alteration in CASP8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor CASP8 expression. Decide whether this perturbation leads to a significant alteration in CASP8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":228
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor C1GALT1 expression. Decide whether this perturbation leads to a significant alteration in C1GALT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor C1GALT1 expression. Decide whether this perturbation leads to a significant alteration in C1GALT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2008
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of SETX. Does this perturbation cause a significant change in SETX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of SETX. Does this perturbation cause a significant change in SETX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3364
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of SLC27A2 is measured. Determine whether SLC27A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of SLC27A2 is measured. Determine whether SLC27A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3686
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of ZC3H7A. Does perturbing TIMM44 lead to a significant change in ZC3H7A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of ZC3H7A. Does perturbing TIMM44 lead to a significant change in ZC3H7A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3671
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of RP11-573D15.2 is measured. Determine whether RP11-573D15.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of RP11-573D15.2 is measured. Determine whether RP11-573D15.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3886
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in NSD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in NSD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1345
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of NXF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of NXF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3117
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and CDK13 expression is quantified. Does this perturbation result in a significant change in CDK13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and CDK13 expression is quantified. Does this perturbation result in a significant change in CDK13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2762
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PIF1 is measured. Does this perturbation cause a significant change in PIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PIF1 is measured. Does this perturbation cause a significant change in PIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3070
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of MYH7B. Does perturbing YIPF5 lead to a significant change in MYH7B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of MYH7B. Does perturbing YIPF5 lead to a significant change in MYH7B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":581
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of SPCS2. Does this perturbation cause a significant change in SPCS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of SPCS2. Does this perturbation cause a significant change in SPCS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":694
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of LRRC4B is measured. Does this perturbation cause a significant change in LRRC4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of LRRC4B is measured. Does this perturbation cause a significant change in LRRC4B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2170
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of TIPARP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of TIPARP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3617
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and TET1 expression is measured. Determine whether TET1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and TET1 expression is measured. Determine whether TET1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":139
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of NAV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of NAV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4467
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of AC015987.1. Does this perturbation cause a significant change in AC015987.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of AC015987.1. Does this perturbation cause a significant change in AC015987.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2254
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of REST is measured. Does this perturbation cause a significant change in REST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of REST is measured. Does this perturbation cause a significant change in REST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":790
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of TLN1. Does perturbing IARS2 lead to a significant change in TLN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of TLN1. Does perturbing IARS2 lead to a significant change in TLN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1031
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of TOPBP1. Does perturbing TARS lead to a significant change in TOPBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of TOPBP1. Does perturbing TARS lead to a significant change in TOPBP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2891
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor CTD-2020K17.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2020K17.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor CTD-2020K17.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2020K17.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4198
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of RAD51AP1 is measured. Does this perturbation cause a significant change in RAD51AP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of RAD51AP1 is measured. Does this perturbation cause a significant change in RAD51AP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5140
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of RP11-666A20.4. Does this perturbation cause a significant change in RP11-666A20.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of RP11-666A20.4. Does this perturbation cause a significant change in RP11-666A20.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4234
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of MLEC is measured. Determine whether MLEC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of MLEC is measured. Determine whether MLEC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3176
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and LTB expression is observed. Does this perturbation lead to a significant difference in LTB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and LTB expression is observed. Does this perturbation lead to a significant difference in LTB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4703
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of DYNC1H1. Does perturbing ARHGAP22 lead to a significant change in DYNC1H1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of DYNC1H1. Does perturbing ARHGAP22 lead to a significant change in DYNC1H1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3141
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of ARHGAP11A is measured. Does this perturbation cause a significant change in ARHGAP11A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of ARHGAP11A is measured. Does this perturbation cause a significant change in ARHGAP11A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3720
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of NAV2 is measured. Does this perturbation cause a significant change in NAV2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of NAV2 is measured. Does this perturbation cause a significant change in NAV2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4860
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of SBF2 is measured. Does this perturbation cause a significant change in SBF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of SBF2 is measured. Does this perturbation cause a significant change in SBF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2560
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of NPAT. Does perturbing PSMD4 lead to a significant change in NPAT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of NPAT. Does perturbing PSMD4 lead to a significant change in NPAT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3321
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor S100A11 expression. Decide whether this perturbation leads to a significant alteration in S100A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor S100A11 expression. Decide whether this perturbation leads to a significant alteration in S100A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3258
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of EP300. Does this perturbation cause a significant change in EP300 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of EP300. Does this perturbation cause a significant change in EP300 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1684
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor RP11-640M9.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-640M9.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor RP11-640M9.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-640M9.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1128
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of TRIM24 is measured. Does this perturbation cause a significant change in TRIM24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of TRIM24 is measured. Does this perturbation cause a significant change in TRIM24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3190
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and HIST1H2AM expression is observed. Does this perturbation lead to a significant difference in HIST1H2AM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and HIST1H2AM expression is observed. Does this perturbation lead to a significant difference in HIST1H2AM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2423
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and KCNE3 expression is measured. Determine whether KCNE3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and KCNE3 expression is measured. Determine whether KCNE3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1019
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PHF19 is measured. Does this perturbation cause a significant change in PHF19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PHF19 is measured. Does this perturbation cause a significant change in PHF19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3060
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and HIST1H2AC expression is quantified. Does this perturbation result in a significant change in HIST1H2AC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and HIST1H2AC expression is quantified. Does this perturbation result in a significant change in HIST1H2AC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3022
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of RP11-445H22.3. Does perturbing HYOU1 lead to a significant change in RP11-445H22.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of RP11-445H22.3. Does perturbing HYOU1 lead to a significant change in RP11-445H22.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3811
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of RP1-274L7.1. Does this perturbation cause a significant change in RP1-274L7.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of RP1-274L7.1. Does this perturbation cause a significant change in RP1-274L7.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4074
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor GLG1 expression. Decide whether this perturbation leads to a significant alteration in GLG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor GLG1 expression. Decide whether this perturbation leads to a significant alteration in GLG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1948
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of RBM12B-AS1 is measured. Does this perturbation cause a significant change in RBM12B-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of RBM12B-AS1 is measured. Does this perturbation cause a significant change in RBM12B-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2510
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor IDS expression. Decide whether this perturbation leads to a significant alteration in IDS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor IDS expression. Decide whether this perturbation leads to a significant alteration in IDS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4278
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of KANSL1L is measured. Does this perturbation cause a significant change in KANSL1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of KANSL1L is measured. Does this perturbation cause a significant change in KANSL1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":640
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of NRIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of NRIP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3627
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of GCKR. Does perturbing AARS lead to a significant change in GCKR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of GCKR. Does perturbing AARS lead to a significant change in GCKR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4301
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and ZNF429 expression is observed. Does this perturbation lead to a significant difference in ZNF429 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and ZNF429 expression is observed. Does this perturbation lead to a significant difference in ZNF429 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and SPAST expression is measured. Determine whether SPAST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and SPAST expression is measured. Determine whether SPAST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2849
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and RP11-24F11.2 expression is measured. Determine whether RP11-24F11.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and RP11-24F11.2 expression is measured. Determine whether RP11-24F11.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1499
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1694
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of TSPAN33 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of TSPAN33 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3527
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor NAV2 expression. Decide whether this perturbation leads to a significant alteration in NAV2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor NAV2 expression. Decide whether this perturbation leads to a significant alteration in NAV2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4868
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and UBE2V1 expression is observed. Does this perturbation lead to a significant difference in UBE2V1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and UBE2V1 expression is observed. Does this perturbation lead to a significant difference in UBE2V1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1703
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of GATA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of GATA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5117
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of NFE2L3. Does perturbing PDIA6 lead to a significant change in NFE2L3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of NFE2L3. Does perturbing PDIA6 lead to a significant change in NFE2L3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1581
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3509
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of NFE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of NFE2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":217
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor DSC2 expression. Decide whether this perturbation leads to a significant alteration in DSC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor DSC2 expression. Decide whether this perturbation leads to a significant alteration in DSC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4098
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of RP3-465N24.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of RP3-465N24.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3587
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in RP11-181G12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in RP11-181G12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4375
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of RP11-81A22.5 is measured. Determine whether RP11-81A22.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of RP11-81A22.5 is measured. Determine whether RP11-81A22.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1616
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in GATA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in GATA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":885
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of ZNF429. Does this perturbation cause a significant change in ZNF429 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of ZNF429. Does this perturbation cause a significant change in ZNF429 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in RP11-390B4.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in RP11-390B4.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4835
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and C12orf44 expression is observed. Does this perturbation lead to a significant difference in C12orf44 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and C12orf44 expression is observed. Does this perturbation lead to a significant difference in C12orf44 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1533
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and ADAMTS10 expression is quantified. Does this perturbation result in a significant change in ADAMTS10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and ADAMTS10 expression is quantified. Does this perturbation result in a significant change in ADAMTS10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1072
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ZFP36L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ZFP36L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3455
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of JUND is measured. Determine whether JUND shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of JUND is measured. Determine whether JUND shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":776
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RUNX1. Does perturbing MARS lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of RUNX1. Does perturbing MARS lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2731
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in NFAT5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in NFAT5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1815
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor RCBTB2 expression. Decide whether this perturbation leads to a significant alteration in RCBTB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor RCBTB2 expression. Decide whether this perturbation leads to a significant alteration in RCBTB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1338
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of BAMBI. Does perturbing UFL1 lead to a significant change in BAMBI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of BAMBI. Does perturbing UFL1 lead to a significant change in BAMBI expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1171
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of KLF3 is measured. Determine whether KLF3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of KLF3 is measured. Determine whether KLF3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1986
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ARHGAP6 expression is measured. Determine whether ARHGAP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ARHGAP6 expression is measured. Determine whether ARHGAP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3909
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and ZNF678 expression is observed. Does this perturbation lead to a significant difference in ZNF678 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and ZNF678 expression is observed. Does this perturbation lead to a significant difference in ZNF678 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1363
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in RSAD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in RSAD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4405
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and GDF11 expression is quantified. Does this perturbation result in a significant change in GDF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and GDF11 expression is quantified. Does this perturbation result in a significant change in GDF11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":392
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of GSN. Does perturbing TTI1 lead to a significant change in GSN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of GSN. Does perturbing TTI1 lead to a significant change in GSN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3201
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PHF19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PHF19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3067
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor SERPINF2 expression. Decide whether this perturbation leads to a significant alteration in SERPINF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor SERPINF2 expression. Decide whether this perturbation leads to a significant alteration in SERPINF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3958
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of RP11-119J18.1. Does perturbing MRPL39 lead to a significant change in RP11-119J18.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of RP11-119J18.1. Does perturbing MRPL39 lead to a significant change in RP11-119J18.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2441
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor WDR3 expression. Decide whether this perturbation leads to a significant alteration in WDR3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor WDR3 expression. Decide whether this perturbation leads to a significant alteration in WDR3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4568
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of UFD1L is measured. Determine whether UFD1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of UFD1L is measured. Determine whether UFD1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2506
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of PAXBP1. Does this perturbation cause a significant change in PAXBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of PAXBP1. Does this perturbation cause a significant change in PAXBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4744
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and GATA3 expression is measured. Determine whether GATA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and GATA3 expression is measured. Determine whether GATA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":889
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and RP11-573D15.2 expression is quantified. Does this perturbation result in a significant change in RP11-573D15.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and RP11-573D15.2 expression is quantified. Does this perturbation result in a significant change in RP11-573D15.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3882
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RP11-65L19.4. Does perturbing ZNF326 lead to a significant change in RP11-65L19.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RP11-65L19.4. Does perturbing ZNF326 lead to a significant change in RP11-65L19.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of RP11-360L9.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of RP11-360L9.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2797
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of NFE2L3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of NFE2L3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1587
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in SLBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in SLBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2135
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in ZEB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in ZEB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":965
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of BAMBI is measured. Determine whether BAMBI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of BAMBI is measured. Determine whether BAMBI shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1176
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in CDRT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in CDRT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":285
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2780
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor EXOC3L2 expression. Decide whether this perturbation leads to a significant alteration in EXOC3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor EXOC3L2 expression. Decide whether this perturbation leads to a significant alteration in EXOC3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3358
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of MORF4L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of MORF4L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2627
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and GS1-166A23.1 expression is observed. Does this perturbation lead to a significant difference in GS1-166A23.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and GS1-166A23.1 expression is observed. Does this perturbation lead to a significant difference in GS1-166A23.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3293
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of KCNQ1OT1. Does this perturbation cause a significant change in KCNQ1OT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of KCNQ1OT1. Does this perturbation cause a significant change in KCNQ1OT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4624
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of CRNDE is measured. Does this perturbation cause a significant change in CRNDE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of CRNDE is measured. Does this perturbation cause a significant change in CRNDE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1970
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor NOSTRIN expression. Decide whether this perturbation leads to a significant alteration in NOSTRIN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor NOSTRIN expression. Decide whether this perturbation leads to a significant alteration in NOSTRIN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4328
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RP11-685N10.1. Does this perturbation cause a significant change in RP11-685N10.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of RP11-685N10.1. Does this perturbation cause a significant change in RP11-685N10.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2754
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and NAV1 expression is measured. Determine whether NAV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and NAV1 expression is measured. Determine whether NAV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4469
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and RIMS3 expression is observed. Does this perturbation lead to a significant difference in RIMS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and RIMS3 expression is observed. Does this perturbation lead to a significant difference in RIMS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":163
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and RIMS3 expression is measured. Determine whether RIMS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and RIMS3 expression is measured. Determine whether RIMS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":169
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and CCDC69 expression is measured. Determine whether CCDC69 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and CCDC69 expression is measured. Determine whether CCDC69 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3449
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in ARHGAP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in ARHGAP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1755
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of AMOTL1 is measured. Does this perturbation cause a significant change in AMOTL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of AMOTL1 is measured. Does this perturbation cause a significant change in AMOTL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2240
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and MTPN expression is observed. Does this perturbation lead to a significant difference in MTPN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and MTPN expression is observed. Does this perturbation lead to a significant difference in MTPN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4733
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of AC005540.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of AC005540.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4417
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of CTNNB1 is measured. Determine whether CTNNB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of CTNNB1 is measured. Determine whether CTNNB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2456
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of NFE2L3 is measured. Does this perturbation cause a significant change in NFE2L3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of NFE2L3 is measured. Does this perturbation cause a significant change in NFE2L3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1580
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor PDE3B expression. Decide whether this perturbation leads to a significant alteration in PDE3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor PDE3B expression. Decide whether this perturbation leads to a significant alteration in PDE3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4788
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of BOLA3. Does this perturbation cause a significant change in BOLA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of BOLA3. Does this perturbation cause a significant change in BOLA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4634
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of TAP1. Does perturbing SEC61G lead to a significant change in TAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of TAP1. Does perturbing SEC61G lead to a significant change in TAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4711
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and PDE4D expression is measured. Determine whether PDE4D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and PDE4D expression is measured. Determine whether PDE4D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":519
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RP11-65L19.4 expression is observed. Does this perturbation lead to a significant difference in RP11-65L19.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RP11-65L19.4 expression is observed. Does this perturbation lead to a significant difference in RP11-65L19.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of RP11-863K10.7 is measured. Determine whether RP11-863K10.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of RP11-863K10.7 is measured. Determine whether RP11-863K10.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":936
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and HM13 expression is observed. Does this perturbation lead to a significant difference in HM13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and HM13 expression is observed. Does this perturbation lead to a significant difference in HM13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4513
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in TAGLN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in TAGLN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1355
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and PDK2 expression is observed. Does this perturbation lead to a significant difference in PDK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and PDK2 expression is observed. Does this perturbation lead to a significant difference in PDK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2163
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and STARD9 expression is observed. Does this perturbation lead to a significant difference in STARD9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and STARD9 expression is observed. Does this perturbation lead to a significant difference in STARD9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4603
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and HIST1H2AM expression is quantified. Does this perturbation result in a significant change in HIST1H2AM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and HIST1H2AM expression is quantified. Does this perturbation result in a significant change in HIST1H2AM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2422
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2538
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and UQCRB expression is measured. Determine whether UQCRB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and UQCRB expression is measured. Determine whether UQCRB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":709
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and MARCH8 expression is observed. Does this perturbation lead to a significant difference in MARCH8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and MARCH8 expression is observed. Does this perturbation lead to a significant difference in MARCH8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1433
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of ADAMTS10. Does this perturbation cause a significant change in ADAMTS10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of ADAMTS10. Does this perturbation cause a significant change in ADAMTS10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1074
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of DKFZP779L1853. Does this perturbation cause a significant change in DKFZP779L1853 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of DKFZP779L1853. Does this perturbation cause a significant change in DKFZP779L1853 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2384
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of SBF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of SBF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2567
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in RBM12B-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in RBM12B-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2515
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of EP300. Does this perturbation cause a significant change in EP300 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of EP300. Does this perturbation cause a significant change in EP300 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2054
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and WDR72 expression is observed. Does this perturbation lead to a significant difference in WDR72 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and WDR72 expression is observed. Does this perturbation lead to a significant difference in WDR72 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4133
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of SEPT5 is measured. Does this perturbation cause a significant change in SEPT5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of SEPT5 is measured. Does this perturbation cause a significant change in SEPT5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3540
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of HIST1H3D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of HIST1H3D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":917
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of PRRC2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of PRRC2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":907
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and PPP1R16B expression is quantified. Does this perturbation result in a significant change in PPP1R16B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and PPP1R16B expression is quantified. Does this perturbation result in a significant change in PPP1R16B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4482
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of CELF6. Does this perturbation cause a significant change in CELF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of CELF6. Does this perturbation cause a significant change in CELF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5034
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of EXO1. Does this perturbation cause a significant change in EXO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of EXO1. Does this perturbation cause a significant change in EXO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2834
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of USP34 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of USP34 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4367
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of LPAR5. Does perturbing CREB1 lead to a significant change in LPAR5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of LPAR5. Does perturbing CREB1 lead to a significant change in LPAR5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and STC2 expression is measured. Determine whether STC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and STC2 expression is measured. Determine whether STC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":189
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and GS1-166A23.1 expression is quantified. Does this perturbation result in a significant change in GS1-166A23.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and GS1-166A23.1 expression is quantified. Does this perturbation result in a significant change in GS1-166A23.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3292
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of OPTN. Does this perturbation cause a significant change in OPTN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of OPTN. Does this perturbation cause a significant change in OPTN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":554
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor HIST1H2AM expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor HIST1H2AM expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":388
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and PAK1IP1 expression is quantified. Does this perturbation result in a significant change in PAK1IP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and PAK1IP1 expression is quantified. Does this perturbation result in a significant change in PAK1IP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4252
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of DDIT4. Does this perturbation cause a significant change in DDIT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of DDIT4. Does this perturbation cause a significant change in DDIT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1824
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2533
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor RP11-132A1.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-132A1.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor RP11-132A1.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-132A1.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":728
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and PIK3IP1 expression is measured. Determine whether PIK3IP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and PIK3IP1 expression is measured. Determine whether PIK3IP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2869
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of CDRT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of CDRT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":287
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of SMIM14 is measured. Determine whether SMIM14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of SMIM14 is measured. Determine whether SMIM14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3306
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and NTRK1 expression is quantified. Does this perturbation result in a significant change in NTRK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and NTRK1 expression is quantified. Does this perturbation result in a significant change in NTRK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4032
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor WHAMM expression. Decide whether this perturbation leads to a significant alteration in WHAMM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor WHAMM expression. Decide whether this perturbation leads to a significant alteration in WHAMM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":788
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of CD83 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of CD83 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2697
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and HP1BP3 expression is observed. Does this perturbation lead to a significant difference in HP1BP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and HP1BP3 expression is observed. Does this perturbation lead to a significant difference in HP1BP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":613
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of MBNL1. Does this perturbation cause a significant change in MBNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of MBNL1. Does this perturbation cause a significant change in MBNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4814
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor C9orf64 expression. Decide whether this perturbation leads to a significant alteration in C9orf64 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor C9orf64 expression. Decide whether this perturbation leads to a significant alteration in C9orf64 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3878
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and CD83 expression is observed. Does this perturbation lead to a significant difference in CD83 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and CD83 expression is observed. Does this perturbation lead to a significant difference in CD83 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2693
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of SNHG7 is measured. Determine whether SNHG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of SNHG7 is measured. Determine whether SNHG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4046
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor STC2 expression. Decide whether this perturbation leads to a significant alteration in STC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor STC2 expression. Decide whether this perturbation leads to a significant alteration in STC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":188
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor GUSB expression. Decide whether this perturbation leads to a significant alteration in GUSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor GUSB expression. Decide whether this perturbation leads to a significant alteration in GUSB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1408
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of LRIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of LRIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1457
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of RP11-381O7.3. Does this perturbation cause a significant change in RP11-381O7.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of RP11-381O7.3. Does this perturbation cause a significant change in RP11-381O7.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1554
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of SPEN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of SPEN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1577
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor ROCK1 expression. Decide whether this perturbation leads to a significant alteration in ROCK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor ROCK1 expression. Decide whether this perturbation leads to a significant alteration in ROCK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5158
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of FCGRT is measured. Determine whether FCGRT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of FCGRT is measured. Determine whether FCGRT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3536
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of C17orf64 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of C17orf64 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3717
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of ESCO1 is measured. Does this perturbation cause a significant change in ESCO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of ESCO1 is measured. Does this perturbation cause a significant change in ESCO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":860
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and ATF7IP2 expression is observed. Does this perturbation lead to a significant difference in ATF7IP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and ATF7IP2 expression is observed. Does this perturbation lead to a significant difference in ATF7IP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4523
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of RP11-838N2.4 is measured. Does this perturbation cause a significant change in RP11-838N2.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of RP11-838N2.4 is measured. Does this perturbation cause a significant change in RP11-838N2.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3030
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in PTPRC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in PTPRC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":235
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of TNFRSF10B. Does this perturbation cause a significant change in TNFRSF10B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of TNFRSF10B. Does this perturbation cause a significant change in TNFRSF10B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2284
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of EIF3A. Does perturbing XRN1 lead to a significant change in EIF3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of EIF3A. Does perturbing XRN1 lead to a significant change in EIF3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4801
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of ATAD2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of ATAD2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4397
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in TAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in TAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4715
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of ZNF678 is measured. Does this perturbation cause a significant change in ZNF678 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of ZNF678 is measured. Does this perturbation cause a significant change in ZNF678 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1360
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of MT2A is measured. Does this perturbation cause a significant change in MT2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of MT2A is measured. Does this perturbation cause a significant change in MT2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3160
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of SLC37A1. Does perturbing UFL1 lead to a significant change in SLC37A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of SLC37A1. Does perturbing UFL1 lead to a significant change in SLC37A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1151
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of HRK is measured. Does this perturbation cause a significant change in HRK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of HRK is measured. Does this perturbation cause a significant change in HRK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1040
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and SHOX2 expression is measured. Determine whether SHOX2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and SHOX2 expression is measured. Determine whether SHOX2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":999
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and DUT expression is measured. Determine whether DUT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and DUT expression is measured. Determine whether DUT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":279
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and ERP29 expression is measured. Determine whether ERP29 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and ERP29 expression is measured. Determine whether ERP29 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5079
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of TKTL1 is measured. Does this perturbation cause a significant change in TKTL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of TKTL1 is measured. Does this perturbation cause a significant change in TKTL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":170
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and PARP11 expression is observed. Does this perturbation lead to a significant difference in PARP11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and PARP11 expression is observed. Does this perturbation lead to a significant difference in PARP11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3703
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of CLDN11 is measured. Determine whether CLDN11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of CLDN11 is measured. Determine whether CLDN11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2616
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in C1GALT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in C1GALT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2005
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and ROCK1 expression is measured. Determine whether ROCK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and ROCK1 expression is measured. Determine whether ROCK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5159
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of LTBP1. Does this perturbation cause a significant change in LTBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of LTBP1. Does this perturbation cause a significant change in LTBP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1804
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in MYH7B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in MYH7B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":585
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and TUBA1C expression is observed. Does this perturbation lead to a significant difference in TUBA1C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and TUBA1C expression is observed. Does this perturbation lead to a significant difference in TUBA1C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3393
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of YTHDF2 is measured. Does this perturbation cause a significant change in YTHDF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of YTHDF2 is measured. Does this perturbation cause a significant change in YTHDF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4920
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RP11-685N10.1 expression is measured. Determine whether RP11-685N10.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and RP11-685N10.1 expression is measured. Determine whether RP11-685N10.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2759
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and RGS3 expression is quantified. Does this perturbation result in a significant change in RGS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and RGS3 expression is quantified. Does this perturbation result in a significant change in RGS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2872
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and RP11-81A22.5 expression is measured. Determine whether RP11-81A22.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and RP11-81A22.5 expression is measured. Determine whether RP11-81A22.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1619
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in RP11-360L9.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in RP11-360L9.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4295
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of RP11-360L9.8 is measured. Does this perturbation cause a significant change in RP11-360L9.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of RP11-360L9.8 is measured. Does this perturbation cause a significant change in RP11-360L9.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4290
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and RP11-390B4.5 expression is observed. Does this perturbation lead to a significant difference in RP11-390B4.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and RP11-390B4.5 expression is observed. Does this perturbation lead to a significant difference in RP11-390B4.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4833
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of SETX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of SETX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2477
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of RP11-212I21.4. Does this perturbation cause a significant change in RP11-212I21.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of RP11-212I21.4. Does this perturbation cause a significant change in RP11-212I21.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2034
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in PDK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in PDK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2165
  }
]