,question,answer,question_new
2356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of ENSG00000169410 is measured. Determine whether ENSG00000169410 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of PTPN9 is measured. Determine whether PTPN9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
738,"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor ENSG00000168209 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000168209 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor DDIT4 expression. Decide whether this perturbation leads to a significant alteration in DDIT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2190,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of ENSG00000119535. Does perturbing CITED1 lead to a significant change in ENSG00000119535 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of CSF3R. Does perturbing CITED1 lead to a significant change in CSF3R expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and ENSG00000204482 expression is measured. Determine whether ENSG00000204482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of ENSG00000163513. Does perturbing TGFBR2 lead to a significant change in ENSG00000163513 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of TGFBR2. Does perturbing TGFBR2 lead to a significant change in TGFBR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2403,You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and ENSG00000237330 expression is observed. Does this perturbation lead to a significant difference in ENSG00000237330 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and RNF223 expression is observed. Does this perturbation lead to a significant difference in RNF223 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
92,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and ENSG00000092067 expression is measured. Determine whether ENSG00000092067 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and CEBPE expression is measured. Determine whether CEBPE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1130,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of ENSG00000069482 is measured. Does this perturbation cause a significant change in ENSG00000069482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of GAL is measured. Does this perturbation cause a significant change in GAL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1043,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and ENSG00000090382 expression is observed. Does this perturbation lead to a significant difference in ENSG00000090382 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and LYZ expression is observed. Does this perturbation lead to a significant difference in LYZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and ENSG00000143401 expression is quantified. Does this perturbation result in a significant change in ENSG00000143401 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and ANP32E expression is quantified. Does this perturbation result in a significant change in ANP32E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of ENSG00000130656. Does perturbing SAMD1 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of HBZ. Does perturbing SAMD1 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2383,You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and ENSG00000069482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000069482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and GAL expression is observed. Does this perturbation lead to a significant difference in GAL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and ENSG00000157557 expression is quantified. Does this perturbation result in a significant change in ENSG00000157557 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and ETS2 expression is quantified. Does this perturbation result in a significant change in ETS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1370,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of ENSG00000117091 is measured. Does this perturbation cause a significant change in ENSG00000117091 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of CD48 is measured. Does this perturbation cause a significant change in CD48 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of ENSG00000185198. Does this perturbation cause a significant change in ENSG00000185198 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
510,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of ENSG00000092067 is measured. Does this perturbation cause a significant change in ENSG00000092067 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of CEBPE is measured. Does this perturbation cause a significant change in CEBPE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
408,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of ENSG00000170689 is measured. Determine whether ENSG00000170689 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of HOXB9 is measured. Determine whether HOXB9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of ENSG00000170542. Does this perturbation cause a significant change in ENSG00000170542 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of SERPINB9. Does this perturbation cause a significant change in SERPINB9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and ENSG00000279529 expression is measured. Determine whether ENSG00000279529 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and CTD-3222D19.8 expression is measured. Determine whether CTD-3222D19.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of ENSG00000118515. Does perturbing SGK1 lead to a significant change in ENSG00000118515 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of SGK1. Does perturbing SGK1 lead to a significant change in SGK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of ENSG00000101076 is measured. Determine whether ENSG00000101076 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of HNF4A is measured. Determine whether HNF4A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1763,You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and ENSG00000163531 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163531 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and NFASC expression is observed. Does this perturbation lead to a significant difference in NFASC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in ENSG00000186051 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in TAL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2070,"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of ENSG00000189171 is measured. Does this perturbation cause a significant change in ENSG00000189171 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and ENSG00000115844 expression is quantified. Does this perturbation result in a significant change in ENSG00000115844 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and DLX2 expression is quantified. Does this perturbation result in a significant change in DLX2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of ENSG00000108821. Does this perturbation cause a significant change in ENSG00000108821 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of COL1A1. Does this perturbation cause a significant change in COL1A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1143,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and ENSG00000184481 expression is observed. Does this perturbation lead to a significant difference in ENSG00000184481 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and FOXO4 expression is observed. Does this perturbation lead to a significant difference in FOXO4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2050,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of ENSG00000128016 is measured. Does this perturbation cause a significant change in ENSG00000128016 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of ZFP36 is measured. Does this perturbation cause a significant change in ZFP36 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
890,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of ENSG00000069482 is measured. Does this perturbation cause a significant change in ENSG00000069482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of GAL is measured. Does this perturbation cause a significant change in GAL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of ENSG00000172331 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of BPGM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of ENSG00000157557. Does perturbing ETS2 lead to a significant change in ENSG00000157557 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of ETS2. Does perturbing ETS2 lead to a significant change in ETS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of ENSG00000163499. Does perturbing FEV lead to a significant change in ENSG00000163499 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of CRYBA2. Does perturbing FEV lead to a significant change in CRYBA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of ENSG00000153094 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of BCL2L11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1688,"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor ENSG00000118058 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000118058 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor KMT2A expression. Decide whether this perturbation leads to a significant alteration in KMT2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2578,"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor ENSG00000268621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000268621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and ENSG00000185198 expression is measured. Determine whether ENSG00000185198 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1053,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and ENSG00000090382 expression is observed. Does this perturbation lead to a significant difference in ENSG00000090382 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and LYZ expression is observed. Does this perturbation lead to a significant difference in LYZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1058,"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor ENSG00000090382 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000090382 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor LYZ expression. Decide whether this perturbation leads to a significant alteration in LYZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and ENSG00000268621 expression is measured. Determine whether ENSG00000268621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of ENSG00000105610. Does this perturbation cause a significant change in ENSG00000105610 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of KLF1. Does this perturbation cause a significant change in KLF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of ENSG00000153012. Does this perturbation cause a significant change in ENSG00000153012 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of LGI2. Does this perturbation cause a significant change in LGI2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2118,"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor ENSG00000164920 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000164920 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor OSR2 expression. Decide whether this perturbation leads to a significant alteration in OSR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and ENSG00000141744 expression is measured. Determine whether ENSG00000141744 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and PNMT expression is measured. Determine whether PNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of ENSG00000104894 is measured. Determine whether ENSG00000104894 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of CD37 is measured. Determine whether CD37 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of ENSG00000277268. Does perturbing LHX1 lead to a significant change in ENSG00000277268 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of RP11-445F12.1. Does perturbing LHX1 lead to a significant change in RP11-445F12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of ENSG00000198758 is measured. Determine whether ENSG00000198758 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of EPS8L3 is measured. Determine whether EPS8L3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in ENSG00000189171 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2553,You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and ENSG00000118515 expression is observed. Does this perturbation lead to a significant difference in ENSG00000118515 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and SGK1 expression is observed. Does this perturbation lead to a significant difference in SGK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of ENSG00000076356. Does perturbing MAML2 lead to a significant change in ENSG00000076356 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of PLXNA2. Does perturbing MAML2 lead to a significant change in PLXNA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of ENSG00000196565 is measured. Determine whether ENSG00000196565 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of HBG2 is measured. Determine whether HBG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of ENSG00000110492. Does this perturbation cause a significant change in ENSG00000110492 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of MDK. Does this perturbation cause a significant change in MDK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and ENSG00000166340 expression is quantified. Does this perturbation result in a significant change in ENSG00000166340 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and TPP1 expression is quantified. Does this perturbation result in a significant change in TPP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
630,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of ENSG00000184697 is measured. Does this perturbation cause a significant change in ENSG00000184697 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of CLDN6 is measured. Does this perturbation cause a significant change in CLDN6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and ENSG00000184481 expression is quantified. Does this perturbation result in a significant change in ENSG00000184481 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and FOXO4 expression is quantified. Does this perturbation result in a significant change in FOXO4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2083,You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and ENSG00000143401 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143401 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and ANP32E expression is observed. Does this perturbation lead to a significant difference in ANP32E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of ENSG00000105223 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of PLD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and ENSG00000137841 expression is measured. Determine whether ENSG00000137841 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and PLCB2 expression is measured. Determine whether PLCB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of ENSG00000184481 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of FOXO4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2273,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and ENSG00000206172 expression is observed. Does this perturbation lead to a significant difference in ENSG00000206172 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and HBA1 expression is observed. Does this perturbation lead to a significant difference in HBA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of ENSG00000090382. Does this perturbation cause a significant change in ENSG00000090382 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of LYZ. Does this perturbation cause a significant change in LYZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of ENSG00000250361. Does perturbing BCL2L11 lead to a significant change in ENSG00000250361 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of GYPB. Does perturbing BCL2L11 lead to a significant change in GYPB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in ENSG00000090382 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in LYZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of ENSG00000135409. Does perturbing BPGM lead to a significant change in ENSG00000135409 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of AMHR2. Does perturbing BPGM lead to a significant change in AMHR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of ENSG00000184384. Does this perturbation cause a significant change in ENSG00000184384 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of MAML2. Does this perturbation cause a significant change in MAML2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of ENSG00000090382 is measured. Determine whether ENSG00000090382 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of LYZ is measured. Determine whether LYZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1873,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
963,You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and ENSG00000163499 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163499 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and CRYBA2 expression is observed. Does this perturbation lead to a significant difference in CRYBA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in ENSG00000100097 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in LGALS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3088,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor ENSG00000247516 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000247516 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor MIR4458HG expression. Decide whether this perturbation leads to a significant alteration in MIR4458HG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of ENSG00000169410 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of PTPN9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of ENSG00000158517 is measured. Determine whether ENSG00000158517 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of NCF1 is measured. Determine whether NCF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
973,You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and ENSG00000163497 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163497 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and FEV expression is observed. Does this perturbation lead to a significant difference in FEV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in ENSG00000144655 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in CSRNP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of ENSG00000141753 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of IGFBP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2508,"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in ENSG00000079102 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in RUNX1T1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in ENSG00000164687 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in FABP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of ENSG00000169410. Does this perturbation cause a significant change in ENSG00000169410 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of PTPN9. Does this perturbation cause a significant change in PTPN9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of ENSG00000125931. Does this perturbation cause a significant change in ENSG00000125931 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of CITED1. Does this perturbation cause a significant change in CITED1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and ENSG00000143401 expression is measured. Determine whether ENSG00000143401 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and ANP32E expression is measured. Determine whether ANP32E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of ENSG00000005187 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of ACSM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and ENSG00000104894 expression is quantified. Does this perturbation result in a significant change in ENSG00000104894 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and CD37 expression is quantified. Does this perturbation result in a significant change in CD37 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of ENSG00000184697. Does perturbing CLDN6 lead to a significant change in ENSG00000184697 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of CLDN6. Does perturbing CLDN6 lead to a significant change in CLDN6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of ENSG00000174498. Does perturbing IGDCC3 lead to a significant change in ENSG00000174498 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of IGDCC3. Does perturbing IGDCC3 lead to a significant change in IGDCC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1410,"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of ENSG00000174498 is measured. Does this perturbation cause a significant change in ENSG00000174498 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of IGDCC3 is measured. Does this perturbation cause a significant change in IGDCC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and ENSG00000144655 expression is quantified. Does this perturbation result in a significant change in ENSG00000144655 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and CSRNP1 expression is quantified. Does this perturbation result in a significant change in CSRNP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of ENSG00000121900. Does perturbing TBX2 lead to a significant change in ENSG00000121900 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of TMEM54. Does perturbing TBX2 lead to a significant change in TMEM54 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of ENSG00000182871 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of COL18A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of ENSG00000159556 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of ISL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of ENSG00000186185 is measured. Determine whether ENSG00000186185 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of KIF18B is measured. Determine whether KIF18B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of ENSG00000111057 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of KRT18 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of ENSG00000105697. Does this perturbation cause a significant change in ENSG00000105697 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of HAMP. Does this perturbation cause a significant change in HAMP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
343,You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of ENSG00000203989. Does this perturbation cause a significant change in ENSG00000203989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of RHOXF2BB. Does this perturbation cause a significant change in RHOXF2BB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of ENSG00000090238 is measured. Determine whether ENSG00000090238 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of YPEL3 is measured. Determine whether YPEL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of ENSG00000090238. Does perturbing FOXO4 lead to a significant change in ENSG00000090238 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of YPEL3. Does perturbing FOXO4 lead to a significant change in YPEL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of ENSG00000166450 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of PRTG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in ENSG00000183770 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in FOXL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
30,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of ENSG00000068078 is measured. Does this perturbation cause a significant change in ENSG00000068078 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of FGFR3 is measured. Does this perturbation cause a significant change in FGFR3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of ENSG00000116871 is measured. Determine whether ENSG00000116871 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of MAP7D1 is measured. Determine whether MAP7D1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3140,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of ENSG00000117139 is measured. Does this perturbation cause a significant change in ENSG00000117139 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of KDM5B is measured. Does this perturbation cause a significant change in KDM5B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and ENSG00000119969 expression is quantified. Does this perturbation result in a significant change in ENSG00000119969 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and HELLS expression is quantified. Does this perturbation result in a significant change in HELLS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of ENSG00000109099 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of PMP22 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of ENSG00000119969 is measured. Determine whether ENSG00000119969 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of HELLS is measured. Determine whether HELLS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and ENSG00000133317 expression is measured. Determine whether ENSG00000133317 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and LGALS12 expression is measured. Determine whether LGALS12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
433,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and ENSG00000187997 expression is observed. Does this perturbation lead to a significant difference in ENSG00000187997 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and C17orf99 expression is observed. Does this perturbation lead to a significant difference in C17orf99 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of ENSG00000139219 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of COL2A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1848,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor ENSG00000108984 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000108984 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor MAP2K6 expression. Decide whether this perturbation leads to a significant alteration in MAP2K6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1170,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of ENSG00000070214 is measured. Does this perturbation cause a significant change in ENSG00000070214 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of SLC44A1 is measured. Does this perturbation cause a significant change in SLC44A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of ENSG00000170180. Does this perturbation cause a significant change in ENSG00000170180 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of GYPA. Does this perturbation cause a significant change in GYPA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in ENSG00000064886 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in CHI3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of ENSG00000170689 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of HOXB9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in ENSG00000206172 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in HBA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in ENSG00000258274 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in RP11-887P2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1033,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and ENSG00000129514 expression is observed. Does this perturbation lead to a significant difference in ENSG00000129514 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and FOXA1 expression is observed. Does this perturbation lead to a significant difference in FOXA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of ENSG00000196565. Does this perturbation cause a significant change in ENSG00000196565 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of HBG2. Does this perturbation cause a significant change in HBG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of ENSG00000163499 is measured. Determine whether ENSG00000163499 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of CRYBA2 is measured. Determine whether CRYBA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
700,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of ENSG00000256713 is measured. Does this perturbation cause a significant change in ENSG00000256713 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of PGA5 is measured. Does this perturbation cause a significant change in PGA5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and ENSG00000258274 expression is measured. Determine whether ENSG00000258274 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and RP11-887P2.5 expression is measured. Determine whether RP11-887P2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of ENSG00000101076 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of HNF4A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of ENSG00000250361 is measured. Determine whether ENSG00000250361 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of GYPB is measured. Determine whether GYPB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of ENSG00000279529 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of CTD-3222D19.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1858,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor ENSG00000266976 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000266976 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor AC079466.1 expression. Decide whether this perturbation leads to a significant alteration in AC079466.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and ENSG00000109099 expression is measured. Determine whether ENSG00000109099 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and PMP22 expression is measured. Determine whether PMP22 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2693,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and ENSG00000189171 expression is observed. Does this perturbation lead to a significant difference in ENSG00000189171 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and S100A13 expression is observed. Does this perturbation lead to a significant difference in S100A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1678,"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor ENSG00000105610 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000105610 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor KLF1 expression. Decide whether this perturbation leads to a significant alteration in KLF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in ENSG00000243449 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in C4orf48 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and ENSG00000170542 expression is measured. Determine whether ENSG00000170542 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and SERPINB9 expression is measured. Determine whether SERPINB9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of ENSG00000243449. Does this perturbation cause a significant change in ENSG00000243449 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of C4orf48. Does this perturbation cause a significant change in C4orf48 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of ENSG00000187997 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of C17orf99 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2453,You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and ENSG00000133317 expression is observed. Does this perturbation lead to a significant difference in ENSG00000133317 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and LGALS12 expression is observed. Does this perturbation lead to a significant difference in LGALS12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and ENSG00000135111 expression is quantified. Does this perturbation result in a significant change in ENSG00000135111 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and TBX3 expression is quantified. Does this perturbation result in a significant change in TBX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and ENSG00000169413 expression is quantified. Does this perturbation result in a significant change in ENSG00000169413 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and RNASE6 expression is quantified. Does this perturbation result in a significant change in RNASE6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in ENSG00000011600 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in TYROBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and ENSG00000102804 expression is measured. Determine whether ENSG00000102804 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and TSC22D1 expression is measured. Determine whether TSC22D1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of ENSG00000101200 is measured. Determine whether ENSG00000101200 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of AVP is measured. Determine whether AVP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and ENSG00000141744 expression is measured. Determine whether ENSG00000141744 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and PNMT expression is measured. Determine whether PNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and ENSG00000169410 expression is quantified. Does this perturbation result in a significant change in ENSG00000169410 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and PTPN9 expression is quantified. Does this perturbation result in a significant change in PTPN9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and ENSG00000135047 expression is quantified. Does this perturbation result in a significant change in ENSG00000135047 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and CTSL expression is quantified. Does this perturbation result in a significant change in CTSL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and ENSG00000234965 expression is measured. Determine whether ENSG00000234965 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and SHISA8 expression is measured. Determine whether SHISA8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and ENSG00000258274 expression is quantified. Does this perturbation result in a significant change in ENSG00000258274 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and RP11-887P2.5 expression is quantified. Does this perturbation result in a significant change in RP11-887P2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2898,"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor ENSG00000255346 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000255346 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor NOX5 expression. Decide whether this perturbation leads to a significant alteration in NOX5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in ENSG00000265972 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of ENSG00000121900. Does this perturbation cause a significant change in ENSG00000121900 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of TMEM54. Does this perturbation cause a significant change in TMEM54 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of ENSG00000204482. Does this perturbation cause a significant change in ENSG00000204482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of ENSG00000121068. Does this perturbation cause a significant change in ENSG00000121068 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of TBX2. Does this perturbation cause a significant change in TBX2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
553,You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and ENSG00000245848 expression is observed. Does this perturbation lead to a significant difference in ENSG00000245848 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and CEBPA expression is observed. Does this perturbation lead to a significant difference in CEBPA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of ENSG00000135047. Does this perturbation cause a significant change in ENSG00000135047 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of CTSL. Does this perturbation cause a significant change in CTSL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
308,"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor ENSG00000196565 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000196565 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor HBG2 expression. Decide whether this perturbation leads to a significant alteration in HBG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and ENSG00000163497 expression is measured. Determine whether ENSG00000163497 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and FEV expression is measured. Determine whether FEV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of ENSG00000189171 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of S100A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of ENSG00000197766. Does this perturbation cause a significant change in ENSG00000197766 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of CFD. Does this perturbation cause a significant change in CFD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of ENSG00000108984. Does this perturbation cause a significant change in ENSG00000108984 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of MAP2K6. Does this perturbation cause a significant change in MAP2K6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of ENSG00000119535 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of CSF3R indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1503,You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and ENSG00000159556 expression is observed. Does this perturbation lead to a significant difference in ENSG00000159556 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and ISL2 expression is observed. Does this perturbation lead to a significant difference in ISL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and ENSG00000250361 expression is quantified. Does this perturbation result in a significant change in ENSG00000250361 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and GYPB expression is quantified. Does this perturbation result in a significant change in GYPB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1953,You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of ENSG00000204472. Does this perturbation cause a significant change in ENSG00000204472 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of AIF1. Does this perturbation cause a significant change in AIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in ENSG00000121900 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in TMEM54 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of ENSG00000140287. Does this perturbation cause a significant change in ENSG00000140287 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of HDC. Does this perturbation cause a significant change in HDC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of ENSG00000129514. Does this perturbation cause a significant change in ENSG00000129514 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of FOXA1. Does this perturbation cause a significant change in FOXA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of ENSG00000188483. Does this perturbation cause a significant change in ENSG00000188483 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of IER5L. Does this perturbation cause a significant change in IER5L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
370,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of ENSG00000124762 is measured. Does this perturbation cause a significant change in ENSG00000124762 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of ENSG00000141744. Does this perturbation cause a significant change in ENSG00000141744 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of PNMT. Does this perturbation cause a significant change in PNMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and ENSG00000141744 expression is measured. Determine whether ENSG00000141744 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and PNMT expression is measured. Determine whether PNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1988,"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor ENSG00000185198 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000185198 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2150,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of ENSG00000119969 is measured. Does this perturbation cause a significant change in ENSG00000119969 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of HELLS is measured. Does this perturbation cause a significant change in HELLS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of ENSG00000101200 is measured. Determine whether ENSG00000101200 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of AVP is measured. Determine whether AVP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and ENSG00000273706 expression is quantified. Does this perturbation result in a significant change in ENSG00000273706 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and LHX1 expression is quantified. Does this perturbation result in a significant change in LHX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
730,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of ENSG00000168209 is measured. Does this perturbation cause a significant change in ENSG00000168209 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of DDIT4 is measured. Does this perturbation cause a significant change in DDIT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
843,You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and ENSG00000130829 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130829 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and DUSP9 expression is observed. Does this perturbation lead to a significant difference in DUSP9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of ENSG00000106031 is measured. Determine whether ENSG00000106031 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of HOXA13 is measured. Determine whether HOXA13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
993,You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and ENSG00000149516 expression is observed. Does this perturbation lead to a significant difference in ENSG00000149516 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and MS4A3 expression is observed. Does this perturbation lead to a significant difference in MS4A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of ENSG00000090238 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of YPEL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and ENSG00000158517 expression is quantified. Does this perturbation result in a significant change in ENSG00000158517 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and NCF1 expression is quantified. Does this perturbation result in a significant change in NCF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of ENSG00000183770. Does this perturbation cause a significant change in ENSG00000183770 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of FOXL2. Does this perturbation cause a significant change in FOXL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in ENSG00000163497 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in FEV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1900,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of ENSG00000135047. Does this perturbation cause a significant change in ENSG00000135047 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of CTSL. Does this perturbation cause a significant change in CTSL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of ENSG00000185198 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and ENSG00000185198 expression is quantified. Does this perturbation result in a significant change in ENSG00000185198 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2173,You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and ENSG00000140287 expression is observed. Does this perturbation lead to a significant difference in ENSG00000140287 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and HDC expression is observed. Does this perturbation lead to a significant difference in HDC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2213,You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in ENSG00000141753 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in IGFBP4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
513,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and ENSG00000092067 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092067 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and CEBPE expression is observed. Does this perturbation lead to a significant difference in CEBPE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
518,"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor ENSG00000092067 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092067 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor CEBPE expression. Decide whether this perturbation leads to a significant alteration in CEBPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2260,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of ENSG00000185198 is measured. Does this perturbation cause a significant change in ENSG00000185198 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1200,"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of ENSG00000179111 is measured. Does this perturbation cause a significant change in ENSG00000179111 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of HES7 is measured. Does this perturbation cause a significant change in HES7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of ENSG00000170608. Does perturbing FOXA3 lead to a significant change in ENSG00000170608 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of FOXA3. Does perturbing FOXA3 lead to a significant change in FOXA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of ENSG00000141753. Does this perturbation cause a significant change in ENSG00000141753 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of IGFBP4. Does this perturbation cause a significant change in IGFBP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and ENSG00000258274 expression is quantified. Does this perturbation result in a significant change in ENSG00000258274 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and RP11-887P2.5 expression is quantified. Does this perturbation result in a significant change in RP11-887P2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in ENSG00000149516 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in MS4A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of ENSG00000069482 is measured. Determine whether ENSG00000069482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of GAL is measured. Determine whether GAL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of ENSG00000071967 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of CYBRD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of ENSG00000206172. Does this perturbation cause a significant change in ENSG00000206172 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of HBA1. Does this perturbation cause a significant change in HBA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in ENSG00000198758 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in EPS8L3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2970,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of ENSG00000154127 is measured. Does this perturbation cause a significant change in ENSG00000154127 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of UBASH3B is measured. Does this perturbation cause a significant change in UBASH3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of ENSG00000240065. Does perturbing IRF1 lead to a significant change in ENSG00000240065 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of PSMB9. Does perturbing IRF1 lead to a significant change in PSMB9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1490,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of ENSG00000071967 is measured. Does this perturbation cause a significant change in ENSG00000071967 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of CYBRD1 is measured. Does this perturbation cause a significant change in CYBRD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of ENSG00000250361. Does perturbing MEIS1 lead to a significant change in ENSG00000250361 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of GYPB. Does perturbing MEIS1 lead to a significant change in GYPB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
778,"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor ENSG00000104894 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000104894 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor CD37 expression. Decide whether this perturbation leads to a significant alteration in CD37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of ENSG00000130656. Does perturbing BPGM lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of HBZ. Does perturbing BPGM lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of ENSG00000011600 is measured. Determine whether ENSG00000011600 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of TYROBP is measured. Determine whether TYROBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2728,"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor ENSG00000011600 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000011600 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor TYROBP expression. Decide whether this perturbation leads to a significant alteration in TYROBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2610,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of ENSG00000254614 is measured. Does this perturbation cause a significant change in ENSG00000254614 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of AP003068.23 is measured. Does this perturbation cause a significant change in AP003068.23 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1933,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and ENSG00000116871 expression is observed. Does this perturbation lead to a significant difference in ENSG00000116871 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and MAP7D1 expression is observed. Does this perturbation lead to a significant difference in MAP7D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2288,"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1773,You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and ENSG00000184384 expression is observed. Does this perturbation lead to a significant difference in ENSG00000184384 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and MAML2 expression is observed. Does this perturbation lead to a significant difference in MAML2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
39,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and ENSG00000068078 expression is measured. Determine whether ENSG00000068078 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and FGFR3 expression is measured. Determine whether FGFR3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of ENSG00000189171. Does this perturbation cause a significant change in ENSG00000189171 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of S100A13. Does this perturbation cause a significant change in S100A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2550,"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of ENSG00000118515 is measured. Does this perturbation cause a significant change in ENSG00000118515 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of SGK1 is measured. Does this perturbation cause a significant change in SGK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and ENSG00000076356 expression is quantified. Does this perturbation result in a significant change in ENSG00000076356 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and PLXNA2 expression is quantified. Does this perturbation result in a significant change in PLXNA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of ENSG00000075624 is measured. Determine whether ENSG00000075624 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of ACTB is measured. Determine whether ACTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of ENSG00000188536. Does this perturbation cause a significant change in ENSG00000188536 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of HBA2. Does this perturbation cause a significant change in HBA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
648,"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor ENSG00000184697 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000184697 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor CLDN6 expression. Decide whether this perturbation leads to a significant alteration in CLDN6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of ENSG00000108821. Does perturbing COL1A1 lead to a significant change in ENSG00000108821 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of COL1A1. Does perturbing COL1A1 lead to a significant change in COL1A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of ENSG00000163499 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of CRYBA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2820,"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of ENSG00000163513 is measured. Does this perturbation cause a significant change in ENSG00000163513 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of TGFBR2 is measured. Does this perturbation cause a significant change in TGFBR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in ENSG00000245532 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in NEAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
37,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of ENSG00000068078 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of FGFR3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ENSG00000099625 expression is measured. Determine whether ENSG00000099625 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and C19orf26 expression is measured. Determine whether C19orf26 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1760,"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of ENSG00000163531 is measured. Does this perturbation cause a significant change in ENSG00000163531 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of NFASC is measured. Does this perturbation cause a significant change in NFASC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of ENSG00000168209. Does perturbing COL1A1 lead to a significant change in ENSG00000168209 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of DDIT4. Does perturbing COL1A1 lead to a significant change in DDIT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1428,"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor ENSG00000174498 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000174498 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor IGDCC3 expression. Decide whether this perturbation leads to a significant alteration in IGDCC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of ENSG00000205542 is measured. Determine whether ENSG00000205542 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of TMSB4X is measured. Determine whether TMSB4X shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of ENSG00000079102. Does this perturbation cause a significant change in ENSG00000079102 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of RUNX1T1. Does this perturbation cause a significant change in RUNX1T1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of ENSG00000106991. Does perturbing PTPN13 lead to a significant change in ENSG00000106991 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of ENG. Does perturbing PTPN13 lead to a significant change in ENG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in ENSG00000123473 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in STIL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2500,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of ENSG00000103241. Does this perturbation cause a significant change in ENSG00000103241 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of FOXF1. Does this perturbation cause a significant change in FOXF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in ENSG00000141744 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in PNMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and ENSG00000108984 expression is measured. Determine whether ENSG00000108984 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and MAP2K6 expression is measured. Determine whether MAP2K6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and ENSG00000142945 expression is quantified. Does this perturbation result in a significant change in ENSG00000142945 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and KIF2C expression is quantified. Does this perturbation result in a significant change in KIF2C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of ENSG00000142945. Does this perturbation cause a significant change in ENSG00000142945 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of KIF2C. Does this perturbation cause a significant change in KIF2C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of ENSG00000170542. Does perturbing SET lead to a significant change in ENSG00000170542 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of SERPINB9. Does perturbing SET lead to a significant change in SERPINB9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1798,"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor ENSG00000113594 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000113594 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor LIFR expression. Decide whether this perturbation leads to a significant alteration in LIFR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and ENSG00000163499 expression is quantified. Does this perturbation result in a significant change in ENSG00000163499 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and CRYBA2 expression is quantified. Does this perturbation result in a significant change in CRYBA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and ENSG00000185198 expression is quantified. Does this perturbation result in a significant change in ENSG00000185198 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of ENSG00000140287 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of HDC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2910,"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of ENSG00000102804 is measured. Does this perturbation cause a significant change in ENSG00000102804 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of TSC22D1 is measured. Does this perturbation cause a significant change in TSC22D1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of ENSG00000188483. Does perturbing IER5L lead to a significant change in ENSG00000188483 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of IER5L. Does perturbing IER5L lead to a significant change in IER5L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of ENSG00000184384 is measured. Determine whether ENSG00000184384 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of MAML2 is measured. Determine whether MAML2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and ENSG00000118777 expression is quantified. Does this perturbation result in a significant change in ENSG00000118777 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and ABCG2 expression is quantified. Does this perturbation result in a significant change in ABCG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of ENSG00000184384. Does perturbing MAML2 lead to a significant change in ENSG00000184384 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of MAML2. Does perturbing MAML2 lead to a significant change in MAML2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
490,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of ENSG00000153012 is measured. Does this perturbation cause a significant change in ENSG00000153012 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of LGI2 is measured. Does this perturbation cause a significant change in LGI2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of ENSG00000183770. Does this perturbation cause a significant change in ENSG00000183770 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of FOXL2. Does this perturbation cause a significant change in FOXL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of ENSG00000117091 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of CD48 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in ENSG00000204482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2818,"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor ENSG00000135111 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000135111 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor TBX3 expression. Decide whether this perturbation leads to a significant alteration in TBX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1723,You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and ENSG00000277268 expression is observed. Does this perturbation lead to a significant difference in ENSG00000277268 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and RP11-445F12.1 expression is observed. Does this perturbation lead to a significant difference in RP11-445F12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of ENSG00000121068 is measured. Determine whether ENSG00000121068 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of TBX2 is measured. Determine whether TBX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and ENSG00000085185 expression is quantified. Does this perturbation result in a significant change in ENSG00000085185 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and BCORL1 expression is quantified. Does this perturbation result in a significant change in BCORL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1890,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
413,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and ENSG00000129757 expression is observed. Does this perturbation lead to a significant difference in ENSG00000129757 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and CDKN1C expression is observed. Does this perturbation lead to a significant difference in CDKN1C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and ENSG00000170608 expression is measured. Determine whether ENSG00000170608 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and FOXA3 expression is measured. Determine whether FOXA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
558,"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor ENSG00000245848 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000245848 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor CEBPA expression. Decide whether this perturbation leads to a significant alteration in CEBPA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of ENSG00000005187 is measured. Determine whether ENSG00000005187 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of ACSM3 is measured. Determine whether ACSM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of ENSG00000005187 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of ACSM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and ENSG00000183019 expression is measured. Determine whether ENSG00000183019 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and MCEMP1 expression is measured. Determine whether MCEMP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and ENSG00000105223 expression is measured. Determine whether ENSG00000105223 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and PLD3 expression is measured. Determine whether PLD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2200,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of ENSG00000110492 is measured. Does this perturbation cause a significant change in ENSG00000110492 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of MDK is measured. Does this perturbation cause a significant change in MDK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of ENSG00000148180. Does this perturbation cause a significant change in ENSG00000148180 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of GSN. Does this perturbation cause a significant change in GSN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and ENSG00000189171 expression is measured. Determine whether ENSG00000189171 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1028,"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor ENSG00000129514 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000129514 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor FOXA1 expression. Decide whether this perturbation leads to a significant alteration in FOXA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and ENSG00000174498 expression is measured. Determine whether ENSG00000174498 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and IGDCC3 expression is measured. Determine whether IGDCC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of ENSG00000158578. Does perturbing CDKN1A lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of ALAS2. Does perturbing CDKN1A lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and ENSG00000168140 expression is measured. Determine whether ENSG00000168140 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and VASN expression is measured. Determine whether VASN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and ENSG00000204482 expression is measured. Determine whether ENSG00000204482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of ENSG00000077063. Does perturbing KIF18B lead to a significant change in ENSG00000077063 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of CTTNBP2. Does perturbing KIF18B lead to a significant change in CTTNBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and ENSG00000114315 expression is quantified. Does this perturbation result in a significant change in ENSG00000114315 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and HES1 expression is quantified. Does this perturbation result in a significant change in HES1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in ENSG00000163520 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in FBLN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1203,You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and ENSG00000179111 expression is observed. Does this perturbation lead to a significant difference in ENSG00000179111 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and HES7 expression is observed. Does this perturbation lead to a significant difference in HES7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and ENSG00000279576 expression is quantified. Does this perturbation result in a significant change in ENSG00000279576 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and AP000769.1 expression is quantified. Does this perturbation result in a significant change in AP000769.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of ENSG00000268621 is measured. Determine whether ENSG00000268621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of ENSG00000250361. Does perturbing POU3F2 lead to a significant change in ENSG00000250361 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of GYPB. Does perturbing POU3F2 lead to a significant change in GYPB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2760,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of ENSG00000121900 is measured. Does this perturbation cause a significant change in ENSG00000121900 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of TMEM54 is measured. Does this perturbation cause a significant change in TMEM54 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of ENSG00000205542 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of TMSB4X indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of ENSG00000069011. Does perturbing HES7 lead to a significant change in ENSG00000069011 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of PITX1. Does perturbing HES7 lead to a significant change in PITX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of ENSG00000163499 is measured. Determine whether ENSG00000163499 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of CRYBA2 is measured. Determine whether CRYBA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2023,You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and ENSG00000168140 expression is observed. Does this perturbation lead to a significant difference in ENSG00000168140 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and VASN expression is observed. Does this perturbation lead to a significant difference in VASN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and ENSG00000186051 expression is measured. Determine whether ENSG00000186051 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and TAL2 expression is measured. Determine whether TAL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of ENSG00000064886 is measured. Determine whether ENSG00000064886 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of CHI3L2 is measured. Determine whether CHI3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
698,"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and ENSG00000163531 expression is measured. Determine whether ENSG00000163531 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and NFASC expression is measured. Determine whether NFASC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of ENSG00000115255. Does this perturbation cause a significant change in ENSG00000115255 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of REEP6. Does this perturbation cause a significant change in REEP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
85,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in ENSG00000115758 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in ODC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and ENSG00000177606 expression is measured. Determine whether ENSG00000177606 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and JUN expression is measured. Determine whether JUN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and ENSG00000004939 expression is quantified. Does this perturbation result in a significant change in ENSG00000004939 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and SLC4A1 expression is quantified. Does this perturbation result in a significant change in SLC4A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of ENSG00000179111 is measured. Determine whether ENSG00000179111 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of HES7 is measured. Determine whether HES7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2890,"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of ENSG00000255346 is measured. Does this perturbation cause a significant change in ENSG00000255346 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of NOX5 is measured. Does this perturbation cause a significant change in NOX5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1100,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of ENSG00000189171 is measured. Does this perturbation cause a significant change in ENSG00000189171 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of ENSG00000141744 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of PNMT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and ENSG00000205277 expression is measured. Determine whether ENSG00000205277 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and MUC12 expression is measured. Determine whether MUC12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in ENSG00000273706 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in LHX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1098,"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor ENSG00000103241 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000103241 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor FOXF1 expression. Decide whether this perturbation leads to a significant alteration in FOXF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in ENSG00000268621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of ENSG00000186185. Does perturbing KIF18B lead to a significant change in ENSG00000186185 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of KIF18B. Does perturbing KIF18B lead to a significant change in KIF18B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of ENSG00000188536. Does perturbing IKZF3 lead to a significant change in ENSG00000188536 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of HBA2. Does perturbing IKZF3 lead to a significant change in HBA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
668,"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor ENSG00000130176 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130176 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor CNN1 expression. Decide whether this perturbation leads to a significant alteration in CNN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of ENSG00000149516. Does this perturbation cause a significant change in ENSG00000149516 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of MS4A3. Does this perturbation cause a significant change in MS4A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2660,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of ENSG00000120738 is measured. Does this perturbation cause a significant change in ENSG00000120738 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of EGR1 is measured. Does this perturbation cause a significant change in EGR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2283,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
86,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of ENSG00000115758 is measured. Determine whether ENSG00000115758 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of ODC1 is measured. Determine whether ODC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of ENSG00000026297. Does this perturbation cause a significant change in ENSG00000026297 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of RNASET2. Does this perturbation cause a significant change in RNASET2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and ENSG00000196565 expression is quantified. Does this perturbation result in a significant change in ENSG00000196565 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and HBG2 expression is quantified. Does this perturbation result in a significant change in HBG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in ENSG00000105610 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in KLF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of ENSG00000116871. Does perturbing MAP7D1 lead to a significant change in ENSG00000116871 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of MAP7D1. Does perturbing MAP7D1 lead to a significant change in MAP7D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of ENSG00000187997 is measured. Determine whether ENSG00000187997 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of C17orf99 is measured. Determine whether C17orf99 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of ENSG00000260793. Does this perturbation cause a significant change in ENSG00000260793 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of RP5-882C2.2. Does this perturbation cause a significant change in RP5-882C2.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3010,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of ENSG00000070214 is measured. Does this perturbation cause a significant change in ENSG00000070214 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of SLC44A1 is measured. Does this perturbation cause a significant change in SLC44A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and ENSG00000129514 expression is measured. Determine whether ENSG00000129514 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and FOXA1 expression is measured. Determine whether FOXA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in ENSG00000004939 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in SLC4A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of ENSG00000129757 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of CDKN1C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in ENSG00000115255 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in REEP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and ENSG00000164920 expression is quantified. Does this perturbation result in a significant change in ENSG00000164920 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and OSR2 expression is quantified. Does this perturbation result in a significant change in OSR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of ENSG00000250361 is measured. Determine whether ENSG00000250361 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of GYPB is measured. Determine whether GYPB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of ENSG00000166501. Does this perturbation cause a significant change in ENSG00000166501 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of PRKCB. Does this perturbation cause a significant change in PRKCB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1263,You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and ENSG00000101076 expression is observed. Does this perturbation lead to a significant difference in ENSG00000101076 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and HNF4A expression is observed. Does this perturbation lead to a significant difference in HNF4A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of ENSG00000141744 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of PNMT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of ENSG00000179111. Does perturbing HES7 lead to a significant change in ENSG00000179111 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of HES7. Does perturbing HES7 lead to a significant change in HES7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
710,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of ENSG00000170180 is measured. Does this perturbation cause a significant change in ENSG00000170180 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of GYPA is measured. Does this perturbation cause a significant change in GYPA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
54,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of ENSG00000160838. Does this perturbation cause a significant change in ENSG00000160838 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of LRRC71. Does this perturbation cause a significant change in LRRC71 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in ENSG00000163513 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in TGFBR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
533,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and ENSG00000204482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000204482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of ENSG00000196565. Does this perturbation cause a significant change in ENSG00000196565 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of HBG2. Does this perturbation cause a significant change in HBG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and ENSG00000134294 expression is quantified. Does this perturbation result in a significant change in ENSG00000134294 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and SLC38A2 expression is quantified. Does this perturbation result in a significant change in SLC38A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1853,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and ENSG00000266976 expression is observed. Does this perturbation lead to a significant difference in ENSG00000266976 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and AC079466.1 expression is observed. Does this perturbation lead to a significant difference in AC079466.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of ENSG00000240065 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of PSMB9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of ENSG00000182871. Does perturbing PTPN13 lead to a significant change in ENSG00000182871 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of COL18A1. Does perturbing PTPN13 lead to a significant change in COL18A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2490,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
723,You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and ENSG00000108821 expression is observed. Does this perturbation lead to a significant difference in ENSG00000108821 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and COL1A1 expression is observed. Does this perturbation lead to a significant difference in COL1A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of ENSG00000166340. Does this perturbation cause a significant change in ENSG00000166340 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of TPP1. Does this perturbation cause a significant change in TPP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and ENSG00000268621 expression is measured. Determine whether ENSG00000268621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1510,"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of ENSG00000141744 is measured. Does this perturbation cause a significant change in ENSG00000141744 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of PNMT is measured. Does this perturbation cause a significant change in PNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
350,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1448,"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor ENSG00000188536 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188536 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor HBA2 expression. Decide whether this perturbation leads to a significant alteration in HBA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and ENSG00000092067 expression is quantified. Does this perturbation result in a significant change in ENSG00000092067 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and CEBPE expression is quantified. Does this perturbation result in a significant change in CEBPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of ENSG00000255346 is measured. Determine whether ENSG00000255346 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of NOX5 is measured. Determine whether NOX5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1328,"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor ENSG00000170689 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000170689 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor HOXB9 expression. Decide whether this perturbation leads to a significant alteration in HOXB9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of ENSG00000121900. Does this perturbation cause a significant change in ENSG00000121900 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of TMEM54. Does this perturbation cause a significant change in TMEM54 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and ENSG00000143498 expression is measured. Determine whether ENSG00000143498 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and TAF1A expression is measured. Determine whether TAF1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of ENSG00000141744. Does this perturbation cause a significant change in ENSG00000141744 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of PNMT. Does this perturbation cause a significant change in PNMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in ENSG00000204472 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in AIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and ENSG00000196188 expression is quantified. Does this perturbation result in a significant change in ENSG00000196188 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and CTSE expression is quantified. Does this perturbation result in a significant change in CTSE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2968,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor ENSG00000141753 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000141753 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor IGFBP4 expression. Decide whether this perturbation leads to a significant alteration in IGFBP4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
95,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of ENSG00000159556. Does this perturbation cause a significant change in ENSG00000159556 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of ISL2. Does this perturbation cause a significant change in ISL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2028,"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor ENSG00000168140 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000168140 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor VASN expression. Decide whether this perturbation leads to a significant alteration in VASN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of ENSG00000204482. Does this perturbation cause a significant change in ENSG00000204482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2333,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and ENSG00000186051 expression is observed. Does this perturbation lead to a significant difference in ENSG00000186051 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and TAL2 expression is observed. Does this perturbation lead to a significant difference in TAL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
11,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of ENSG00000106546. Does perturbing AHR lead to a significant change in ENSG00000106546 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of AHR. Does perturbing AHR lead to a significant change in AHR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of ENSG00000127831. Does this perturbation cause a significant change in ENSG00000127831 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of VIL1. Does this perturbation cause a significant change in VIL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3020,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of ENSG00000070214 is measured. Does this perturbation cause a significant change in ENSG00000070214 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of SLC44A1 is measured. Does this perturbation cause a significant change in SLC44A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in ENSG00000108984 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in MAP2K6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of ENSG00000157557 is measured. Determine whether ENSG00000157557 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of ETS2 is measured. Determine whether ETS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of ENSG00000069482. Does this perturbation cause a significant change in ENSG00000069482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of GAL. Does this perturbation cause a significant change in GAL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of ENSG00000118058 is measured. Determine whether ENSG00000118058 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of KMT2A is measured. Determine whether KMT2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1178,"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor ENSG00000070214 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000070214 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor SLC44A1 expression. Decide whether this perturbation leads to a significant alteration in SLC44A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2338,"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor ENSG00000186051 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000186051 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor TAL2 expression. Decide whether this perturbation leads to a significant alteration in TAL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of ENSG00000159388 is measured. Determine whether ENSG00000159388 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of BTG2 is measured. Determine whether BTG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of ENSG00000134294 is measured. Determine whether ENSG00000134294 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of SLC38A2 is measured. Determine whether SLC38A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of ENSG00000092067. Does this perturbation cause a significant change in ENSG00000092067 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of CEBPE. Does this perturbation cause a significant change in CEBPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in ENSG00000137841 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in PLCB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
270,"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of ENSG00000237330 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of RNF223 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of ENSG00000166450. Does this perturbation cause a significant change in ENSG00000166450 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of PRTG. Does this perturbation cause a significant change in PRTG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of ENSG00000129757. Does this perturbation cause a significant change in ENSG00000129757 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of CDKN1C. Does this perturbation cause a significant change in CDKN1C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2633,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and ENSG00000004939 expression is observed. Does this perturbation lead to a significant difference in ENSG00000004939 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and SLC4A1 expression is observed. Does this perturbation lead to a significant difference in SLC4A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of ENSG00000240065 is measured. Determine whether ENSG00000240065 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of PSMB9 is measured. Determine whether PSMB9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and ENSG00000196565 expression is measured. Determine whether ENSG00000196565 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and HBG2 expression is measured. Determine whether HBG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2460,"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of ENSG00000206172 is measured. Does this perturbation cause a significant change in ENSG00000206172 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of HBA1 is measured. Does this perturbation cause a significant change in HBA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of ENSG00000116871 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of MAP7D1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of ENSG00000158578. Does perturbing IGDCC3 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of ALAS2. Does perturbing IGDCC3 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of ENSG00000124762 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1768,"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor ENSG00000163531 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163531 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor NFASC expression. Decide whether this perturbation leads to a significant alteration in NFASC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of ENSG00000158517. Does this perturbation cause a significant change in ENSG00000158517 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of NCF1. Does this perturbation cause a significant change in NCF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in ENSG00000184486 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in POU3F2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
67,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of ENSG00000268621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of ENSG00000168209. Does this perturbation cause a significant change in ENSG00000168209 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of DDIT4. Does this perturbation cause a significant change in DDIT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1878,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
89,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and ENSG00000115758 expression is measured. Determine whether ENSG00000115758 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and ODC1 expression is measured. Determine whether ODC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and ENSG00000104903 expression is quantified. Does this perturbation result in a significant change in ENSG00000104903 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and LYL1 expression is quantified. Does this perturbation result in a significant change in LYL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
583,You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and ENSG00000119535 expression is observed. Does this perturbation lead to a significant difference in ENSG00000119535 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and CSF3R expression is observed. Does this perturbation lead to a significant difference in CSF3R expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of ENSG00000135111. Does perturbing TBX3 lead to a significant change in ENSG00000135111 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of TBX3. Does perturbing TBX3 lead to a significant change in TBX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and ENSG00000141753 expression is quantified. Does this perturbation result in a significant change in ENSG00000141753 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and IGFBP4 expression is quantified. Does this perturbation result in a significant change in IGFBP4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and ENSG00000166450 expression is quantified. Does this perturbation result in a significant change in ENSG00000166450 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and PRTG expression is quantified. Does this perturbation result in a significant change in PRTG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2153,You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and ENSG00000119969 expression is observed. Does this perturbation lead to a significant difference in ENSG00000119969 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and HELLS expression is observed. Does this perturbation lead to a significant difference in HELLS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of ENSG00000114315. Does perturbing MIDN lead to a significant change in ENSG00000114315 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of HES1. Does perturbing MIDN lead to a significant change in HES1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in ENSG00000005187 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in ACSM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in ENSG00000113594 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in LIFR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in ENSG00000204472 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in AIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of ENSG00000119535. Does perturbing SGK1 lead to a significant change in ENSG00000119535 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of CSF3R. Does perturbing SGK1 lead to a significant change in CSF3R expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3013,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and ENSG00000070214 expression is observed. Does this perturbation lead to a significant difference in ENSG00000070214 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and SLC44A1 expression is observed. Does this perturbation lead to a significant difference in SLC44A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1153,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and ENSG00000166340 expression is observed. Does this perturbation lead to a significant difference in ENSG00000166340 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and TPP1 expression is observed. Does this perturbation lead to a significant difference in TPP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in ENSG00000174498 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in IGDCC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
228,"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor ENSG00000135409 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000135409 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor AMHR2 expression. Decide whether this perturbation leads to a significant alteration in AMHR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
328,"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor ENSG00000213934 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000213934 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor HBG1 expression. Decide whether this perturbation leads to a significant alteration in HBG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and ENSG00000183770 expression is measured. Determine whether ENSG00000183770 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and FOXL2 expression is measured. Determine whether FOXL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and ENSG00000070214 expression is measured. Determine whether ENSG00000070214 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and SLC44A1 expression is measured. Determine whether SLC44A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of ENSG00000187997. Does this perturbation cause a significant change in ENSG00000187997 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of C17orf99. Does this perturbation cause a significant change in C17orf99 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2473,You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and ENSG00000188536 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188536 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and HBA2 expression is observed. Does this perturbation lead to a significant difference in HBA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of ENSG00000108984 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of MAP2K6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and ENSG00000179111 expression is quantified. Does this perturbation result in a significant change in ENSG00000179111 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and HES7 expression is quantified. Does this perturbation result in a significant change in HES7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2793,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and ENSG00000101200 expression is observed. Does this perturbation lead to a significant difference in ENSG00000101200 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and AVP expression is observed. Does this perturbation lead to a significant difference in AVP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of ENSG00000143498. Does perturbing STIL lead to a significant change in ENSG00000143498 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of TAF1A. Does perturbing STIL lead to a significant change in TAF1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1360,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of ENSG00000258274 is measured. Does this perturbation cause a significant change in ENSG00000258274 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of RP11-887P2.5 is measured. Does this perturbation cause a significant change in RP11-887P2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of ENSG00000101200 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of AVP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1183,You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and ENSG00000163520 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163520 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and FBLN2 expression is observed. Does this perturbation lead to a significant difference in FBLN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of ENSG00000234965. Does perturbing SET lead to a significant change in ENSG00000234965 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of SHISA8. Does perturbing SET lead to a significant change in SHISA8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of ENSG00000158578. Does perturbing CLDN6 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of ALAS2. Does perturbing CLDN6 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and ENSG00000153012 expression is measured. Determine whether ENSG00000153012 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and LGI2 expression is measured. Determine whether LGI2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and ENSG00000204472 expression is measured. Determine whether ENSG00000204472 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and AIF1 expression is measured. Determine whether AIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3050,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and ENSG00000115053 expression is measured. Determine whether ENSG00000115053 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and NCL expression is measured. Determine whether NCL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
410,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of ENSG00000129757 is measured. Does this perturbation cause a significant change in ENSG00000129757 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of CDKN1C is measured. Does this perturbation cause a significant change in CDKN1C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
560,"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of ENSG00000204482 is measured. Does this perturbation cause a significant change in ENSG00000204482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in ENSG00000184009 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in ACTG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in ENSG00000196565 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in HBG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and ENSG00000185198 expression is measured. Determine whether ENSG00000185198 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in ENSG00000158517 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in NCF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2250,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2783,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and ENSG00000121068 expression is observed. Does this perturbation lead to a significant difference in ENSG00000121068 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and TBX2 expression is observed. Does this perturbation lead to a significant difference in TBX2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1223,You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and ENSG00000105223 expression is observed. Does this perturbation lead to a significant difference in ENSG00000105223 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and PLD3 expression is observed. Does this perturbation lead to a significant difference in PLD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of ENSG00000158578. Does perturbing DUSP9 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of ALAS2. Does perturbing DUSP9 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and ENSG00000188536 expression is measured. Determine whether ENSG00000188536 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and HBA2 expression is measured. Determine whether HBA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of ENSG00000133317. Does perturbing RUNX1T1 lead to a significant change in ENSG00000133317 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of LGALS12. Does perturbing RUNX1T1 lead to a significant change in LGALS12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and ENSG00000030110 expression is quantified. Does this perturbation result in a significant change in ENSG00000030110 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and BAK1 expression is quantified. Does this perturbation result in a significant change in BAK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and ENSG00000227053 expression is measured. Determine whether ENSG00000227053 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and RP11-395B7.4 expression is measured. Determine whether RP11-395B7.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of ENSG00000279529 is measured. Determine whether ENSG00000279529 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of CTD-3222D19.8 is measured. Determine whether CTD-3222D19.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of ENSG00000265972 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1558,"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor ENSG00000159388 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000159388 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor BTG2 expression. Decide whether this perturbation leads to a significant alteration in BTG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in ENSG00000189171 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of ENSG00000115738 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of ID2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of ENSG00000159388. Does perturbing JUN lead to a significant change in ENSG00000159388 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of BTG2. Does perturbing JUN lead to a significant change in BTG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
128,"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor ENSG00000273706 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000273706 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor LHX1 expression. Decide whether this perturbation leads to a significant alteration in LHX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of ENSG00000189171. Does perturbing SNAI1 lead to a significant change in ENSG00000189171 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of S100A13. Does perturbing SNAI1 lead to a significant change in S100A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1150,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of ENSG00000166340 is measured. Does this perturbation cause a significant change in ENSG00000166340 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of TPP1 is measured. Does this perturbation cause a significant change in TPP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and ENSG00000108984 expression is quantified. Does this perturbation result in a significant change in ENSG00000108984 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and MAP2K6 expression is quantified. Does this perturbation result in a significant change in MAP2K6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of ENSG00000245848 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of CEBPA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1530,"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of ENSG00000069535 is measured. Does this perturbation cause a significant change in ENSG00000069535 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of MAOB is measured. Does this perturbation cause a significant change in MAOB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1513,You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and ENSG00000141744 expression is observed. Does this perturbation lead to a significant difference in ENSG00000141744 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and PNMT expression is observed. Does this perturbation lead to a significant difference in PNMT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of ENSG00000129514 is measured. Determine whether ENSG00000129514 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of FOXA1 is measured. Determine whether FOXA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of ENSG00000166450 is measured. Determine whether ENSG00000166450 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of PRTG is measured. Determine whether PRTG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2790,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of ENSG00000101200 is measured. Does this perturbation cause a significant change in ENSG00000101200 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of AVP is measured. Does this perturbation cause a significant change in AVP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in ENSG00000158373 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in HIST1H2BD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of ENSG00000157557 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of ETS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of ENSG00000106031. Does perturbing HOXA13 lead to a significant change in ENSG00000106031 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of HOXA13. Does perturbing HOXA13 lead to a significant change in HOXA13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and ENSG00000064886 expression is quantified. Does this perturbation result in a significant change in ENSG00000064886 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and CHI3L2 expression is quantified. Does this perturbation result in a significant change in CHI3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and ENSG00000101076 expression is quantified. Does this perturbation result in a significant change in ENSG00000101076 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and HNF4A expression is quantified. Does this perturbation result in a significant change in HNF4A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1123,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and ENSG00000183770 expression is observed. Does this perturbation lead to a significant difference in ENSG00000183770 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and FOXL2 expression is observed. Does this perturbation lead to a significant difference in FOXL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of ENSG00000092067 is measured. Determine whether ENSG00000092067 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of CEBPE is measured. Determine whether CEBPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of ENSG00000100097 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of LGALS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1430,"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and ENSG00000064886 expression is measured. Determine whether ENSG00000064886 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and CHI3L2 expression is measured. Determine whether CHI3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of ENSG00000169410. Does perturbing PTPN9 lead to a significant change in ENSG00000169410 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of PTPN9. Does perturbing PTPN9 lead to a significant change in PTPN9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2753,You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and ENSG00000203989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000203989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and RHOXF2BB expression is observed. Does this perturbation lead to a significant difference in RHOXF2BB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of ENSG00000196517 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of SLC6A9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of ENSG00000002586 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of CD99 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and ENSG00000128016 expression is measured. Determine whether ENSG00000128016 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and ZFP36 expression is measured. Determine whether ZFP36 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and ENSG00000227053 expression is quantified. Does this perturbation result in a significant change in ENSG00000227053 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and RP11-395B7.4 expression is quantified. Does this perturbation result in a significant change in RP11-395B7.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of ENSG00000115255 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of REEP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1133,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and ENSG00000069482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000069482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and GAL expression is observed. Does this perturbation lead to a significant difference in GAL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and ENSG00000250361 expression is measured. Determine whether ENSG00000250361 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and GYPB expression is measured. Determine whether GYPB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of ENSG00000204472 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of AIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in ENSG00000090238 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in YPEL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of ENSG00000121068 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of TBX2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and ENSG00000064886 expression is measured. Determine whether ENSG00000064886 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and CHI3L2 expression is measured. Determine whether CHI3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of ENSG00000143401 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of ANP32E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1710,"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of ENSG00000273706 is measured. Does this perturbation cause a significant change in ENSG00000273706 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of LHX1 is measured. Does this perturbation cause a significant change in LHX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of ENSG00000148180 is measured. Determine whether ENSG00000148180 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of GSN is measured. Determine whether GSN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of ENSG00000143369 is measured. Determine whether ENSG00000143369 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of ECM1 is measured. Determine whether ECM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of ENSG00000185198. Does perturbing UBASH3B lead to a significant change in ENSG00000185198 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of PRSS57. Does perturbing UBASH3B lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
610,"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of ENSG00000140545 is measured. Does this perturbation cause a significant change in ENSG00000140545 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of MFGE8 is measured. Does this perturbation cause a significant change in MFGE8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and ENSG00000166501 expression is measured. Determine whether ENSG00000166501 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and PRKCB expression is measured. Determine whether PRKCB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1928,"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor ENSG00000116871 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000116871 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor MAP7D1 expression. Decide whether this perturbation leads to a significant alteration in MAP7D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
618,"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor ENSG00000140545 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000140545 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor MFGE8 expression. Decide whether this perturbation leads to a significant alteration in MFGE8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of ENSG00000124762 is measured. Determine whether ENSG00000124762 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of CDKN1A is measured. Determine whether CDKN1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and ENSG00000204472 expression is measured. Determine whether ENSG00000204472 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and AIF1 expression is measured. Determine whether AIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of ENSG00000123473. Does this perturbation cause a significant change in ENSG00000123473 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of STIL. Does this perturbation cause a significant change in STIL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3003,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and ENSG00000118777 expression is observed. Does this perturbation lead to a significant difference in ENSG00000118777 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and ABCG2 expression is observed. Does this perturbation lead to a significant difference in ABCG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and ENSG00000159388 expression is quantified. Does this perturbation result in a significant change in ENSG00000159388 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and BTG2 expression is quantified. Does this perturbation result in a significant change in BTG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of ENSG00000120738. Does perturbing SLC6A9 lead to a significant change in ENSG00000120738 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of EGR1. Does perturbing SLC6A9 lead to a significant change in EGR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
628,"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor ENSG00000115255 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000115255 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor REEP6 expression. Decide whether this perturbation leads to a significant alteration in REEP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of ENSG00000079102. Does perturbing RUNX1T1 lead to a significant change in ENSG00000079102 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of RUNX1T1. Does perturbing RUNX1T1 lead to a significant change in RUNX1T1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and ENSG00000117139 expression is measured. Determine whether ENSG00000117139 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and KDM5B expression is measured. Determine whether KDM5B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in ENSG00000234965 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in SHISA8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2123,You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and ENSG00000197965 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197965 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and MPZL1 expression is observed. Does this perturbation lead to a significant difference in MPZL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
80,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of ENSG00000115758 is measured. Does this perturbation cause a significant change in ENSG00000115758 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of ODC1 is measured. Does this perturbation cause a significant change in ODC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of ENSG00000158373 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of HIST1H2BD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of ENSG00000125931. Does perturbing CITED1 lead to a significant change in ENSG00000125931 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of CITED1. Does perturbing CITED1 lead to a significant change in CITED1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of ENSG00000204482 is measured. Determine whether ENSG00000204482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
580,"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of ENSG00000119535 is measured. Does this perturbation cause a significant change in ENSG00000119535 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of CSF3R is measured. Does this perturbation cause a significant change in CSF3R expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and ENSG00000277268 expression is quantified. Does this perturbation result in a significant change in ENSG00000277268 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and RP11-445F12.1 expression is quantified. Does this perturbation result in a significant change in RP11-445F12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and ENSG00000005187 expression is quantified. Does this perturbation result in a significant change in ENSG00000005187 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and ACSM3 expression is quantified. Does this perturbation result in a significant change in ACSM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of ENSG00000115844. Does perturbing DLX2 lead to a significant change in ENSG00000115844 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of DLX2. Does perturbing DLX2 lead to a significant change in DLX2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of ENSG00000206172 is measured. Determine whether ENSG00000206172 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of HBA1 is measured. Determine whether HBA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of ENSG00000069482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of GAL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of ENSG00000069482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of GAL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1440,"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of ENSG00000188536 is measured. Does this perturbation cause a significant change in ENSG00000188536 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of HBA2 is measured. Does this perturbation cause a significant change in HBA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2068,"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor ENSG00000197766 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197766 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor CFD expression. Decide whether this perturbation leads to a significant alteration in CFD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and ENSG00000254614 expression is quantified. Does this perturbation result in a significant change in ENSG00000254614 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and AP003068.23 expression is quantified. Does this perturbation result in a significant change in AP003068.23 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of ENSG00000102804 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of TSC22D1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2908,"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor ENSG00000064886 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000064886 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor CHI3L2 expression. Decide whether this perturbation leads to a significant alteration in CHI3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of ENSG00000070214 is measured. Determine whether ENSG00000070214 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of SLC44A1 is measured. Determine whether SLC44A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and ENSG00000273706 expression is measured. Determine whether ENSG00000273706 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and LHX1 expression is measured. Determine whether LHX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
150,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of ENSG00000153094 is measured. Does this perturbation cause a significant change in ENSG00000153094 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of BCL2L11 is measured. Does this perturbation cause a significant change in BCL2L11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and ENSG00000163531 expression is quantified. Does this perturbation result in a significant change in ENSG00000163531 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and NFASC expression is quantified. Does this perturbation result in a significant change in NFASC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of ENSG00000135047 is measured. Determine whether ENSG00000135047 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of CTSL is measured. Determine whether CTSL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
71,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of ENSG00000113369. Does perturbing ARRDC3 lead to a significant change in ENSG00000113369 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of ARRDC3. Does perturbing ARRDC3 lead to a significant change in ARRDC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of ENSG00000111057. Does this perturbation cause a significant change in ENSG00000111057 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of KRT18. Does this perturbation cause a significant change in KRT18 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1248,"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor ENSG00000265972 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000265972 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and ENSG00000197965 expression is quantified. Does this perturbation result in a significant change in ENSG00000197965 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and MPZL1 expression is quantified. Does this perturbation result in a significant change in MPZL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and ENSG00000156030 expression is measured. Determine whether ENSG00000156030 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and ELMSAN1 expression is measured. Determine whether ELMSAN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and ENSG00000109099 expression is quantified. Does this perturbation result in a significant change in ENSG00000109099 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and PMP22 expression is quantified. Does this perturbation result in a significant change in PMP22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of ENSG00000121900 is measured. Determine whether ENSG00000121900 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of TMEM54 is measured. Determine whether TMEM54 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and ENSG00000186185 expression is measured. Determine whether ENSG00000186185 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and KIF18B expression is measured. Determine whether KIF18B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and ENSG00000139219 expression is measured. Determine whether ENSG00000139219 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and COL2A1 expression is measured. Determine whether COL2A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
23,You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and ENSG00000077063 expression is observed. Does this perturbation lead to a significant difference in ENSG00000077063 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and CTTNBP2 expression is observed. Does this perturbation lead to a significant difference in CTTNBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3073,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2780,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of ENSG00000121068 is measured. Does this perturbation cause a significant change in ENSG00000121068 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of TBX2 is measured. Does this perturbation cause a significant change in TBX2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of ENSG00000004939 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of SLC4A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and ENSG00000133317 expression is quantified. Does this perturbation result in a significant change in ENSG00000133317 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and LGALS12 expression is quantified. Does this perturbation result in a significant change in LGALS12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and ENSG00000279669 expression is quantified. Does this perturbation result in a significant change in ENSG00000279669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and RP11-717F1.1 expression is quantified. Does this perturbation result in a significant change in RP11-717F1.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of ENSG00000185198 is measured. Determine whether ENSG00000185198 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of ENSG00000005187 is measured. Determine whether ENSG00000005187 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of ACSM3 is measured. Determine whether ACSM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of ENSG00000115255 is measured. Determine whether ENSG00000115255 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of REEP6 is measured. Determine whether REEP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
55,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in ENSG00000160838 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in LRRC71 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and ENSG00000090382 expression is quantified. Does this perturbation result in a significant change in ENSG00000090382 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and LYZ expression is quantified. Does this perturbation result in a significant change in LYZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of ENSG00000115844. Does this perturbation cause a significant change in ENSG00000115844 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of DLX2. Does this perturbation cause a significant change in DLX2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and ENSG00000128016 expression is quantified. Does this perturbation result in a significant change in ENSG00000128016 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and ZFP36 expression is quantified. Does this perturbation result in a significant change in ZFP36 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and ENSG00000102575 expression is quantified. Does this perturbation result in a significant change in ENSG00000102575 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and ACP5 expression is quantified. Does this perturbation result in a significant change in ACP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2138,"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor ENSG00000137841 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000137841 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor PLCB2 expression. Decide whether this perturbation leads to a significant alteration in PLCB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of ENSG00000106031. Does this perturbation cause a significant change in ENSG00000106031 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of HOXA13. Does this perturbation cause a significant change in HOXA13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
348,"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of ENSG00000135047. Does perturbing MAP4K3 lead to a significant change in ENSG00000135047 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of CTSL. Does perturbing MAP4K3 lead to a significant change in CTSL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2650,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of ENSG00000115844. Does this perturbation cause a significant change in ENSG00000115844 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of DLX2. Does this perturbation cause a significant change in DLX2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and ENSG00000090382 expression is quantified. Does this perturbation result in a significant change in ENSG00000090382 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and LYZ expression is quantified. Does this perturbation result in a significant change in LYZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of ENSG00000130656. Does perturbing SAMD1 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of HBZ. Does perturbing SAMD1 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in ENSG00000115844 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in DLX2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of ENSG00000118777. Does this perturbation cause a significant change in ENSG00000118777 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of ABCG2. Does this perturbation cause a significant change in ABCG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1993,You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and ENSG00000185198 expression is observed. Does this perturbation lead to a significant difference in ENSG00000185198 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1563,You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and ENSG00000143674 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143674 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and KIAA1804 expression is observed. Does this perturbation lead to a significant difference in KIAA1804 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1958,"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1613,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and ENSG00000077063 expression is observed. Does this perturbation lead to a significant difference in ENSG00000077063 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and CTTNBP2 expression is observed. Does this perturbation lead to a significant difference in CTTNBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in ENSG00000185198 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in ENSG00000168209 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in DDIT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and ENSG00000111057 expression is measured. Determine whether ENSG00000111057 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and KRT18 expression is measured. Determine whether KRT18 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of ENSG00000204482. Does perturbing SPI1 lead to a significant change in ENSG00000204482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of LST1. Does perturbing SPI1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of ENSG00000069482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of GAL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and ENSG00000159399 expression is quantified. Does this perturbation result in a significant change in ENSG00000159399 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and HK2 expression is quantified. Does this perturbation result in a significant change in HK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2060,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of ENSG00000197766 is measured. Does this perturbation cause a significant change in ENSG00000197766 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of CFD is measured. Does this perturbation cause a significant change in CFD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of ENSG00000115053. Does this perturbation cause a significant change in ENSG00000115053 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of NCL. Does this perturbation cause a significant change in NCL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2370,"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and ENSG00000002586 expression is measured. Determine whether ENSG00000002586 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and CD99 expression is measured. Determine whether CD99 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
318,"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor ENSG00000196565 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000196565 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor HBG2 expression. Decide whether this perturbation leads to a significant alteration in HBG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
773,You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and ENSG00000104894 expression is observed. Does this perturbation lead to a significant difference in ENSG00000104894 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and CD37 expression is observed. Does this perturbation lead to a significant difference in CD37 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of ENSG00000256713. Does this perturbation cause a significant change in ENSG00000256713 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of PGA5. Does this perturbation cause a significant change in PGA5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of ENSG00000185198. Does this perturbation cause a significant change in ENSG00000185198 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1390,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of ENSG00000188483 is measured. Does this perturbation cause a significant change in ENSG00000188483 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of IER5L is measured. Does this perturbation cause a significant change in IER5L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of ENSG00000185198 is measured. Determine whether ENSG00000185198 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2203,You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and ENSG00000110492 expression is observed. Does this perturbation lead to a significant difference in ENSG00000110492 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and MDK expression is observed. Does this perturbation lead to a significant difference in MDK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in ENSG00000250361 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in GYPB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of ENSG00000119535 is measured. Determine whether ENSG00000119535 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of CSF3R is measured. Determine whether CSF3R shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1973,You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and ENSG00000111348 expression is observed. Does this perturbation lead to a significant difference in ENSG00000111348 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and ARHGDIB expression is observed. Does this perturbation lead to a significant difference in ARHGDIB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
280,"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of ENSG00000102804 is measured. Does this perturbation cause a significant change in ENSG00000102804 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of TSC22D1 is measured. Does this perturbation cause a significant change in TSC22D1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in ENSG00000139219 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in COL2A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of ENSG00000005187 is measured. Determine whether ENSG00000005187 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of ACSM3 is measured. Determine whether ACSM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
783,You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and ENSG00000144655 expression is observed. Does this perturbation lead to a significant difference in ENSG00000144655 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and CSRNP1 expression is observed. Does this perturbation lead to a significant difference in CSRNP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and ENSG00000204482 expression is quantified. Does this perturbation result in a significant change in ENSG00000204482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
430,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of ENSG00000187997 is measured. Does this perturbation cause a significant change in ENSG00000187997 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of C17orf99 is measured. Does this perturbation cause a significant change in C17orf99 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and ENSG00000189171 expression is measured. Determine whether ENSG00000189171 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2400,"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of ENSG00000237330 is measured. Does this perturbation cause a significant change in ENSG00000237330 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of RNF223 is measured. Does this perturbation cause a significant change in RNF223 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
223,You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and ENSG00000135409 expression is observed. Does this perturbation lead to a significant difference in ENSG00000135409 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and AMHR2 expression is observed. Does this perturbation lead to a significant difference in AMHR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2133,You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and ENSG00000137841 expression is observed. Does this perturbation lead to a significant difference in ENSG00000137841 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and PLCB2 expression is observed. Does this perturbation lead to a significant difference in PLCB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1818,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor ENSG00000064886 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000064886 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor CHI3L2 expression. Decide whether this perturbation leads to a significant alteration in CHI3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in ENSG00000134294 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in SLC38A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in ENSG00000125144 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in MT1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of ENSG00000204472 is measured. Determine whether ENSG00000204472 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of AIF1 is measured. Determine whether AIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and ENSG00000183770 expression is quantified. Does this perturbation result in a significant change in ENSG00000183770 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and FOXL2 expression is quantified. Does this perturbation result in a significant change in FOXL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1418,"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor ENSG00000174498 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000174498 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor IGDCC3 expression. Decide whether this perturbation leads to a significant alteration in IGDCC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2800,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of ENSG00000101200 is measured. Does this perturbation cause a significant change in ENSG00000101200 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of AVP is measured. Does this perturbation cause a significant change in AVP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and ENSG00000139219 expression is quantified. Does this perturbation result in a significant change in ENSG00000139219 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and COL2A1 expression is quantified. Does this perturbation result in a significant change in COL2A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of ENSG00000005187. Does perturbing ELMSAN1 lead to a significant change in ENSG00000005187 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of ACSM3. Does perturbing ELMSAN1 lead to a significant change in ACSM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of ENSG00000130176 is measured. Determine whether ENSG00000130176 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of CNN1 is measured. Determine whether CNN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in ENSG00000110492 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in MDK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1883,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and ENSG00000135047 expression is observed. Does this perturbation lead to a significant difference in ENSG00000135047 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and CTSL expression is observed. Does this perturbation lead to a significant difference in CTSL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of ENSG00000140287 is measured. Determine whether ENSG00000140287 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of HDC is measured. Determine whether HDC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2270,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of ENSG00000206172 is measured. Does this perturbation cause a significant change in ENSG00000206172 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of HBA1 is measured. Does this perturbation cause a significant change in HBA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in ENSG00000106031 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in HOXA13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in ENSG00000130176 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in CNN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of ENSG00000160185. Does this perturbation cause a significant change in ENSG00000160185 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of UBASH3A. Does this perturbation cause a significant change in UBASH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2280,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of ENSG00000177606 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of JUN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of ENSG00000113594. Does perturbing MAML2 lead to a significant change in ENSG00000113594 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of LIFR. Does perturbing MAML2 lead to a significant change in LIFR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1940,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of ENSG00000279576 is measured. Does this perturbation cause a significant change in ENSG00000279576 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of AP000769.1 is measured. Does this perturbation cause a significant change in AP000769.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of ENSG00000169413 is measured. Determine whether ENSG00000169413 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of RNASE6 is measured. Determine whether RNASE6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2710,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of ENSG00000204482 is measured. Does this perturbation cause a significant change in ENSG00000204482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1400,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2223,You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and ENSG00000166450 expression is observed. Does this perturbation lead to a significant difference in ENSG00000166450 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and PRTG expression is observed. Does this perturbation lead to a significant difference in PRTG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of ENSG00000258274 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of RP11-887P2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of ENSG00000277268 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of RP11-445F12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in ENSG00000204482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and ENSG00000188483 expression is quantified. Does this perturbation result in a significant change in ENSG00000188483 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and IER5L expression is quantified. Does this perturbation result in a significant change in IER5L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of ENSG00000164687 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of FABP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of ENSG00000154127. Does perturbing UBASH3B lead to a significant change in ENSG00000154127 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of UBASH3B. Does perturbing UBASH3B lead to a significant change in UBASH3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and ENSG00000118515 expression is measured. Determine whether ENSG00000118515 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and SGK1 expression is measured. Determine whether SGK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of ENSG00000168140. Does this perturbation cause a significant change in ENSG00000168140 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of VASN. Does this perturbation cause a significant change in VASN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of ENSG00000185198. Does perturbing HK2 lead to a significant change in ENSG00000185198 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of PRSS57. Does perturbing HK2 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
770,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of ENSG00000104894 is measured. Does this perturbation cause a significant change in ENSG00000104894 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of CD37 is measured. Does this perturbation cause a significant change in CD37 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1438,"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and ENSG00000159399 expression is measured. Determine whether ENSG00000159399 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and HK2 expression is measured. Determine whether HK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2758,"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor ENSG00000203989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000203989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor RHOXF2BB expression. Decide whether this perturbation leads to a significant alteration in RHOXF2BB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of ENSG00000268621. Does this perturbation cause a significant change in ENSG00000268621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of ENSG00000102804. Does this perturbation cause a significant change in ENSG00000102804 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of TSC22D1. Does this perturbation cause a significant change in TSC22D1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1013,You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of ENSG00000204482. Does perturbing CEBPE lead to a significant change in ENSG00000204482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of LST1. Does perturbing CEBPE lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in ENSG00000143498 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in TAF1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of ENSG00000105610 is measured. Determine whether ENSG00000105610 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of KLF1 is measured. Determine whether KLF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2313,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and ENSG00000106991 expression is observed. Does this perturbation lead to a significant difference in ENSG00000106991 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and ENG expression is observed. Does this perturbation lead to a significant difference in ENG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and ENSG00000158373 expression is measured. Determine whether ENSG00000158373 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and HIST1H2BD expression is measured. Determine whether HIST1H2BD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of ENSG00000197965. Does this perturbation cause a significant change in ENSG00000197965 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of MPZL1. Does this perturbation cause a significant change in MPZL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of ENSG00000206172. Does this perturbation cause a significant change in ENSG00000206172 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of HBA1. Does this perturbation cause a significant change in HBA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in ENSG00000101200 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in AVP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1163,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and ENSG00000090238 expression is observed. Does this perturbation lead to a significant difference in ENSG00000090238 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and YPEL3 expression is observed. Does this perturbation lead to a significant difference in YPEL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
70,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of ENSG00000113369 is measured. Does this perturbation cause a significant change in ENSG00000113369 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of ARRDC3 is measured. Does this perturbation cause a significant change in ARRDC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2840,"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
188,"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor ENSG00000085185 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000085185 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor BCORL1 expression. Decide whether this perturbation leads to a significant alteration in BCORL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2418,"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of ENSG00000162493 is measured. Determine whether ENSG00000162493 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of PDPN is measured. Determine whether PDPN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
94,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of ENSG00000070214 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of SLC44A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2093,You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and ENSG00000158373 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158373 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and HIST1H2BD expression is observed. Does this perturbation lead to a significant difference in HIST1H2BD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in ENSG00000185198 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in ENSG00000169410 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in PTPN9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of ENSG00000245848. Does this perturbation cause a significant change in ENSG00000245848 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of CEBPA. Does this perturbation cause a significant change in CEBPA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and ENSG00000134294 expression is measured. Determine whether ENSG00000134294 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and SLC38A2 expression is measured. Determine whether SLC38A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of ENSG00000071967. Does this perturbation cause a significant change in ENSG00000071967 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of CYBRD1. Does this perturbation cause a significant change in CYBRD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
760,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of ENSG00000139219 is measured. Does this perturbation cause a significant change in ENSG00000139219 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of COL2A1 is measured. Does this perturbation cause a significant change in COL2A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of ENSG00000120738. Does this perturbation cause a significant change in ENSG00000120738 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of EGR1. Does this perturbation cause a significant change in EGR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of ENSG00000204482. Does perturbing CEBPA lead to a significant change in ENSG00000204482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of LST1. Does perturbing CEBPA lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and ENSG00000177606 expression is quantified. Does this perturbation result in a significant change in ENSG00000177606 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and JUN expression is quantified. Does this perturbation result in a significant change in JUN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in ENSG00000101076 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in HNF4A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2373,You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of ENSG00000174498 is measured. Determine whether ENSG00000174498 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of IGDCC3 is measured. Determine whether IGDCC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of ENSG00000183770 is measured. Determine whether ENSG00000183770 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of FOXL2 is measured. Determine whether FOXL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2483,You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and ENSG00000105697 expression is observed. Does this perturbation lead to a significant difference in ENSG00000105697 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and HAMP expression is observed. Does this perturbation lead to a significant difference in HAMP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of ENSG00000064886 is measured. Determine whether ENSG00000064886 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of CHI3L2 is measured. Determine whether CHI3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and ENSG00000266976 expression is quantified. Does this perturbation result in a significant change in ENSG00000266976 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and AC079466.1 expression is quantified. Does this perturbation result in a significant change in AC079466.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of ENSG00000119535 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of CSF3R indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2368,"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor ENSG00000185198 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000185198 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of ENSG00000164920 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of OSR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
118,"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor ENSG00000250361 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000250361 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor GYPB expression. Decide whether this perturbation leads to a significant alteration in GYPB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and ENSG00000172331 expression is measured. Determine whether ENSG00000172331 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and BPGM expression is measured. Determine whether BPGM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of ENSG00000141744 is measured. Determine whether ENSG00000141744 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of PNMT is measured. Determine whether PNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1770,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of ENSG00000184384 is measured. Does this perturbation cause a significant change in ENSG00000184384 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of MAML2 is measured. Does this perturbation cause a significant change in MAML2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of ENSG00000130656. Does perturbing EGR1 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of HBZ. Does perturbing EGR1 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and ENSG00000186185 expression is quantified. Does this perturbation result in a significant change in ENSG00000186185 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and KIF18B expression is quantified. Does this perturbation result in a significant change in KIF18B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in ENSG00000109099 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in PMP22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in ENSG00000005187 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in ACSM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of ENSG00000163513 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of TGFBR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of ENSG00000169442. Does perturbing MAPK1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of CD52. Does perturbing MAPK1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of ENSG00000196565. Does perturbing CBFA2T3 lead to a significant change in ENSG00000196565 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of HBG2. Does perturbing CBFA2T3 lead to a significant change in HBG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and ENSG00000106031 expression is quantified. Does this perturbation result in a significant change in ENSG00000106031 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and HOXA13 expression is quantified. Does this perturbation result in a significant change in HOXA13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
820,"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of ENSG00000115844 is measured. Does this perturbation cause a significant change in ENSG00000115844 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of DLX2 is measured. Does this perturbation cause a significant change in DLX2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in ENSG00000119969 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in HELLS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of ENSG00000115053 is measured. Determine whether ENSG00000115053 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of NCL is measured. Determine whether NCL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of ENSG00000139219. Does this perturbation cause a significant change in ENSG00000139219 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of COL2A1. Does this perturbation cause a significant change in COL2A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and ENSG00000118058 expression is quantified. Does this perturbation result in a significant change in ENSG00000118058 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and KMT2A expression is quantified. Does this perturbation result in a significant change in KMT2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and ENSG00000197766 expression is measured. Determine whether ENSG00000197766 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and CFD expression is measured. Determine whether CFD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2680,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of ENSG00000079102. Does this perturbation cause a significant change in ENSG00000079102 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of RUNX1T1. Does this perturbation cause a significant change in RUNX1T1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in ENSG00000153094 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in BCL2L11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and ENSG00000141744 expression is quantified. Does this perturbation result in a significant change in ENSG00000141744 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and PNMT expression is quantified. Does this perturbation result in a significant change in PNMT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1268,"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor ENSG00000101076 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000101076 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor HNF4A expression. Decide whether this perturbation leads to a significant alteration in HNF4A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in ENSG00000005187 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in ACSM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in ENSG00000101200 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in AVP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2713,You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and ENSG00000204482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000204482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1780,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of ENSG00000076356 is measured. Does this perturbation cause a significant change in ENSG00000076356 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of PLXNA2 is measured. Does this perturbation cause a significant change in PLXNA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
420,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and ENSG00000069482 expression is quantified. Does this perturbation result in a significant change in ENSG00000069482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and GAL expression is quantified. Does this perturbation result in a significant change in GAL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and ENSG00000272211 expression is quantified. Does this perturbation result in a significant change in ENSG00000272211 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and RP11-347P5.1 expression is quantified. Does this perturbation result in a significant change in RP11-347P5.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2798,"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor ENSG00000101200 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000101200 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor AVP expression. Decide whether this perturbation leads to a significant alteration in AVP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of ENSG00000158578. Does perturbing RHOXF2BB lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of ALAS2. Does perturbing RHOXF2BB lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
998,"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor ENSG00000149516 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000149516 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor MS4A3 expression. Decide whether this perturbation leads to a significant alteration in MS4A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of ENSG00000144655 is measured. Determine whether ENSG00000144655 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of CSRNP1 is measured. Determine whether CSRNP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of ENSG00000196565 is measured. Determine whether ENSG00000196565 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of HBG2 is measured. Determine whether HBG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of ENSG00000128016. Does this perturbation cause a significant change in ENSG00000128016 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of ZFP36. Does this perturbation cause a significant change in ZFP36 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1788,"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor ENSG00000076356 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000076356 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor PLXNA2 expression. Decide whether this perturbation leads to a significant alteration in PLXNA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2088,"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor ENSG00000143401 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143401 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor ANP32E expression. Decide whether this perturbation leads to a significant alteration in ANP32E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1228,"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor ENSG00000105223 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000105223 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor PLD3 expression. Decide whether this perturbation leads to a significant alteration in PLD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of ENSG00000104894. Does perturbing COL2A1 lead to a significant change in ENSG00000104894 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of CD37. Does perturbing COL2A1 lead to a significant change in CD37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2360,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of ENSG00000185198 is measured. Does this perturbation cause a significant change in ENSG00000185198 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of ENSG00000125144 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of MT1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of ENSG00000185198. Does this perturbation cause a significant change in ENSG00000185198 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
218,"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor ENSG00000172331 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000172331 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor BPGM expression. Decide whether this perturbation leads to a significant alteration in BPGM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of ENSG00000102804. Does this perturbation cause a significant change in ENSG00000102804 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of TSC22D1. Does this perturbation cause a significant change in TSC22D1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2390,"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of ENSG00000196565 is measured. Does this perturbation cause a significant change in ENSG00000196565 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of HBG2 is measured. Does this perturbation cause a significant change in HBG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of ENSG00000121900 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of TMEM54 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2668,"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor ENSG00000120738 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000120738 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor EGR1 expression. Decide whether this perturbation leads to a significant alteration in EGR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and ENSG00000185198 expression is measured. Determine whether ENSG00000185198 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of ENSG00000268621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1980,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of ENSG00000185198 is measured. Does this perturbation cause a significant change in ENSG00000185198 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
330,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of ENSG00000002586 is measured. Does this perturbation cause a significant change in ENSG00000002586 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of CD99 is measured. Does this perturbation cause a significant change in CD99 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1483,You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and ENSG00000240065 expression is observed. Does this perturbation lead to a significant difference in ENSG00000240065 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and PSMB9 expression is observed. Does this perturbation lead to a significant difference in PSMB9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and ENSG00000204482 expression is quantified. Does this perturbation result in a significant change in ENSG00000204482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and ENSG00000273706 expression is quantified. Does this perturbation result in a significant change in ENSG00000273706 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and LHX1 expression is quantified. Does this perturbation result in a significant change in LHX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of ENSG00000130656. Does perturbing PTPN12 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of HBZ. Does perturbing PTPN12 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2238,"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor ENSG00000166450 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000166450 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor PRTG expression. Decide whether this perturbation leads to a significant alteration in PRTG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and ENSG00000160185 expression is measured. Determine whether ENSG00000160185 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and UBASH3A expression is measured. Determine whether UBASH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of ENSG00000157557 is measured. Determine whether ENSG00000157557 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of ETS2 is measured. Determine whether ETS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2278,"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor ENSG00000206172 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000206172 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor HBA1 expression. Decide whether this perturbation leads to a significant alteration in HBA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of ENSG00000120738 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of EGR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and ENSG00000105223 expression is quantified. Does this perturbation result in a significant change in ENSG00000105223 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and PLD3 expression is quantified. Does this perturbation result in a significant change in PLD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2698,"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor ENSG00000189171 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000189171 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor S100A13 expression. Decide whether this perturbation leads to a significant alteration in S100A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
96,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1693,You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and ENSG00000164687 expression is observed. Does this perturbation lead to a significant difference in ENSG00000164687 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and FABP5 expression is observed. Does this perturbation lead to a significant difference in FABP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and ENSG00000106031 expression is measured. Determine whether ENSG00000106031 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and HOXA13 expression is measured. Determine whether HOXA13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and ENSG00000129514 expression is quantified. Does this perturbation result in a significant change in ENSG00000129514 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and FOXA1 expression is quantified. Does this perturbation result in a significant change in FOXA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of ENSG00000254614 is measured. Determine whether ENSG00000254614 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of AP003068.23 is measured. Determine whether AP003068.23 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and ENSG00000153012 expression is quantified. Does this perturbation result in a significant change in ENSG00000153012 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and LGI2 expression is quantified. Does this perturbation result in a significant change in LGI2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
290,"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of ENSG00000183770 is measured. Does this perturbation cause a significant change in ENSG00000183770 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of FOXL2 is measured. Does this perturbation cause a significant change in FOXL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2218,"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of ENSG00000170542 is measured. Determine whether ENSG00000170542 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of SERPINB9 is measured. Determine whether SERPINB9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
563,You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and ENSG00000204482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000204482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of ENSG00000170689. Does this perturbation cause a significant change in ENSG00000170689 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of HOXB9. Does this perturbation cause a significant change in HOXB9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1820,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of ENSG00000069482 is measured. Does this perturbation cause a significant change in ENSG00000069482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of GAL is measured. Does this perturbation cause a significant change in GAL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and ENSG00000186051 expression is quantified. Does this perturbation result in a significant change in ENSG00000186051 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and TAL2 expression is quantified. Does this perturbation result in a significant change in TAL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and ENSG00000116871 expression is measured. Determine whether ENSG00000116871 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and MAP7D1 expression is measured. Determine whether MAP7D1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and ENSG00000123473 expression is measured. Determine whether ENSG00000123473 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and STIL expression is measured. Determine whether STIL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of ENSG00000174498 is measured. Determine whether ENSG00000174498 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of IGDCC3 is measured. Determine whether IGDCC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
98,"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of ENSG00000213934. Does this perturbation cause a significant change in ENSG00000213934 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of HBG1. Does this perturbation cause a significant change in HBG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and ENSG00000180785 expression is quantified. Does this perturbation result in a significant change in ENSG00000180785 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and OR51E1 expression is quantified. Does this perturbation result in a significant change in OR51E1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2420,"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of ENSG00000064886 is measured. Does this perturbation cause a significant change in ENSG00000064886 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of CHI3L2 is measured. Does this perturbation cause a significant change in CHI3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2830,"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of ENSG00000163513 is measured. Does this perturbation cause a significant change in ENSG00000163513 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of TGFBR2 is measured. Does this perturbation cause a significant change in TGFBR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and ENSG00000143674 expression is quantified. Does this perturbation result in a significant change in ENSG00000143674 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and KIAA1804 expression is quantified. Does this perturbation result in a significant change in KIAA1804 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
260,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and ENSG00000070214 expression is quantified. Does this perturbation result in a significant change in ENSG00000070214 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and SLC44A1 expression is quantified. Does this perturbation result in a significant change in SLC44A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3033,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and ENSG00000130303 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130303 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and BST2 expression is observed. Does this perturbation lead to a significant difference in BST2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
640,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of ENSG00000184697 is measured. Does this perturbation cause a significant change in ENSG00000184697 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of CLDN6 is measured. Does this perturbation cause a significant change in CLDN6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of ENSG00000133317 is measured. Determine whether ENSG00000133317 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of LGALS12 is measured. Determine whether LGALS12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2700,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of ENSG00000204482 is measured. Does this perturbation cause a significant change in ENSG00000204482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1593,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and ENSG00000143162 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143162 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and CREG1 expression is observed. Does this perturbation lead to a significant difference in CREG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and ENSG00000265972 expression is measured. Determine whether ENSG00000265972 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of ENSG00000203989 is measured. Determine whether ENSG00000203989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of RHOXF2BB is measured. Determine whether RHOXF2BB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of ENSG00000185198 is measured. Determine whether ENSG00000185198 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and ENSG00000124762 expression is quantified. Does this perturbation result in a significant change in ENSG00000124762 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3118,"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor ENSG00000268621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000268621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1320,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of ENSG00000170689 is measured. Does this perturbation cause a significant change in ENSG00000170689 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of HOXB9 is measured. Does this perturbation cause a significant change in HOXB9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in ENSG00000101200 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in AVP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of ENSG00000069011. Does this perturbation cause a significant change in ENSG00000069011 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of PITX1. Does this perturbation cause a significant change in PITX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of ENSG00000277268 is measured. Determine whether ENSG00000277268 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of RP11-445F12.1 is measured. Determine whether RP11-445F12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in ENSG00000247516 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in MIR4458HG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and ENSG00000141753 expression is measured. Determine whether ENSG00000141753 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and IGFBP4 expression is measured. Determine whether IGFBP4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
50,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of ENSG00000160838 is measured. Does this perturbation cause a significant change in ENSG00000160838 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of LRRC71 is measured. Does this perturbation cause a significant change in LRRC71 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of ENSG00000108984. Does this perturbation cause a significant change in ENSG00000108984 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of MAP2K6. Does this perturbation cause a significant change in MAP2K6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and ENSG00000245532 expression is measured. Determine whether ENSG00000245532 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and NEAT1 expression is measured. Determine whether NEAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of ENSG00000135047. Does perturbing ZC3HAV1 lead to a significant change in ENSG00000135047 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of CTSL. Does perturbing ZC3HAV1 lead to a significant change in CTSL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
69,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and ENSG00000268621 expression is measured. Determine whether ENSG00000268621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and ENSG00000105610 expression is measured. Determine whether ENSG00000105610 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and KLF1 expression is measured. Determine whether KLF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of ENSG00000130176. Does this perturbation cause a significant change in ENSG00000130176 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of CNN1. Does this perturbation cause a significant change in CNN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2220,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of ENSG00000166450 is measured. Does this perturbation cause a significant change in ENSG00000166450 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of PRTG is measured. Does this perturbation cause a significant change in PRTG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of ENSG00000154127 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of UBASH3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of ENSG00000279669. Does this perturbation cause a significant change in ENSG00000279669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of RP11-717F1.1. Does this perturbation cause a significant change in RP11-717F1.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
613,You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and ENSG00000140545 expression is observed. Does this perturbation lead to a significant difference in ENSG00000140545 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and MFGE8 expression is observed. Does this perturbation lead to a significant difference in MFGE8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and ENSG00000154127 expression is quantified. Does this perturbation result in a significant change in ENSG00000154127 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and UBASH3B expression is quantified. Does this perturbation result in a significant change in UBASH3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and ENSG00000140545 expression is measured. Determine whether ENSG00000140545 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and MFGE8 expression is measured. Determine whether MFGE8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
18,"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor ENSG00000106546 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000106546 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor AHR expression. Decide whether this perturbation leads to a significant alteration in AHR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of ENSG00000117139. Does perturbing ZNF318 lead to a significant change in ENSG00000117139 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of KDM5B. Does perturbing ZNF318 lead to a significant change in KDM5B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of ENSG00000179111 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of HES7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in ENSG00000148180 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in GSN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
26,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of ENSG00000077063 is measured. Determine whether ENSG00000077063 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of CTTNBP2 is measured. Determine whether CTTNBP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1283,You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and ENSG00000198758 expression is observed. Does this perturbation lead to a significant difference in ENSG00000198758 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and EPS8L3 expression is observed. Does this perturbation lead to a significant difference in EPS8L3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of ENSG00000266976. Does this perturbation cause a significant change in ENSG00000266976 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of AC079466.1. Does this perturbation cause a significant change in AC079466.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of ENSG00000164920 is measured. Determine whether ENSG00000164920 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of OSR2 is measured. Determine whether OSR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and ENSG00000159556 expression is measured. Determine whether ENSG00000159556 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and ISL2 expression is measured. Determine whether ISL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of ENSG00000184486 is measured. Determine whether ENSG00000184486 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of POU3F2 is measured. Determine whether POU3F2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of ENSG00000077063. Does this perturbation cause a significant change in ENSG00000077063 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of CTTNBP2. Does this perturbation cause a significant change in CTTNBP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of ENSG00000105939. Does this perturbation cause a significant change in ENSG00000105939 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of ZC3HAV1. Does this perturbation cause a significant change in ZC3HAV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of ENSG00000120885 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of CLU indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and ENSG00000268621 expression is quantified. Does this perturbation result in a significant change in ENSG00000268621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of ENSG00000079102 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of RUNX1T1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and ENSG00000183770 expression is measured. Determine whether ENSG00000183770 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and FOXL2 expression is measured. Determine whether FOXL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of ENSG00000070214 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of SLC44A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and ENSG00000245532 expression is quantified. Does this perturbation result in a significant change in ENSG00000245532 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and NEAT1 expression is quantified. Does this perturbation result in a significant change in NEAT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
300,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of ENSG00000196565 is measured. Does this perturbation cause a significant change in ENSG00000196565 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of HBG2 is measured. Does this perturbation cause a significant change in HBG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of ENSG00000111348 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of ARHGDIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in ENSG00000129757 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in CDKN1C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2048,"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor ENSG00000115053 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000115053 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor NCL expression. Decide whether this perturbation leads to a significant alteration in NCL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
65,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in ENSG00000268621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
338,"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor ENSG00000002586 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000002586 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor CD99 expression. Decide whether this perturbation leads to a significant alteration in CD99 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2893,You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and ENSG00000255346 expression is observed. Does this perturbation lead to a significant difference in ENSG00000255346 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and NOX5 expression is observed. Does this perturbation lead to a significant difference in NOX5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1643,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and ENSG00000279529 expression is observed. Does this perturbation lead to a significant difference in ENSG00000279529 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and CTD-3222D19.8 expression is observed. Does this perturbation lead to a significant difference in CTD-3222D19.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and ENSG00000164687 expression is measured. Determine whether ENSG00000164687 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and FABP5 expression is measured. Determine whether FABP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of ENSG00000159399. Does perturbing HK2 lead to a significant change in ENSG00000159399 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of HK2. Does perturbing HK2 lead to a significant change in HK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and ENSG00000237330 expression is measured. Determine whether ENSG00000237330 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and RNF223 expression is measured. Determine whether RNF223 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2590,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of ENSG00000268621 is measured. Does this perturbation cause a significant change in ENSG00000268621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and ENSG00000119535 expression is measured. Determine whether ENSG00000119535 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and CSF3R expression is measured. Determine whether CSF3R exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2588,"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor ENSG00000134294 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000134294 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor SLC38A2 expression. Decide whether this perturbation leads to a significant alteration in SLC38A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of ENSG00000002586 is measured. Determine whether ENSG00000002586 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of CD99 is measured. Determine whether CD99 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
59,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and ENSG00000160838 expression is measured. Determine whether ENSG00000160838 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and LRRC71 expression is measured. Determine whether LRRC71 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and ENSG00000115255 expression is quantified. Does this perturbation result in a significant change in ENSG00000115255 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and REEP6 expression is quantified. Does this perturbation result in a significant change in REEP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2298,"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and ENSG00000121068 expression is quantified. Does this perturbation result in a significant change in ENSG00000121068 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and TBX2 expression is quantified. Does this perturbation result in a significant change in TBX2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1648,"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor ENSG00000279529 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000279529 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor CTD-3222D19.8 expression. Decide whether this perturbation leads to a significant alteration in CTD-3222D19.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of ENSG00000030110. Does perturbing BAK1 lead to a significant change in ENSG00000030110 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of BAK1. Does perturbing BAK1 lead to a significant change in BAK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and ENSG00000005187 expression is measured. Determine whether ENSG00000005187 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and ACSM3 expression is measured. Determine whether ACSM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of ENSG00000121900. Does perturbing TBX2 lead to a significant change in ENSG00000121900 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of TMEM54. Does perturbing TBX2 lead to a significant change in TMEM54 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in ENSG00000231312 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in AC007246.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in ENSG00000163497 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in FEV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and ENSG00000168209 expression is measured. Determine whether ENSG00000168209 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and DDIT4 expression is measured. Determine whether DDIT4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of ENSG00000189171 is measured. Determine whether ENSG00000189171 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of S100A13 is measured. Determine whether S100A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in ENSG00000092067 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in CEBPE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of ENSG00000156030 is measured. Determine whether ENSG00000156030 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of ELMSAN1 is measured. Determine whether ELMSAN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2343,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and ENSG00000169410 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169410 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and PTPN9 expression is observed. Does this perturbation lead to a significant difference in PTPN9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in ENSG00000205277 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in MUC12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3098,"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor ENSG00000105939 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000105939 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor ZC3HAV1 expression. Decide whether this perturbation leads to a significant alteration in ZC3HAV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of ENSG00000144655. Does perturbing CSRNP1 lead to a significant change in ENSG00000144655 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of CSRNP1. Does perturbing CSRNP1 lead to a significant change in CSRNP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
833,You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and ENSG00000026297 expression is observed. Does this perturbation lead to a significant difference in ENSG00000026297 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and RNASET2 expression is observed. Does this perturbation lead to a significant difference in RNASET2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
72,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and ENSG00000113369 expression is quantified. Does this perturbation result in a significant change in ENSG00000113369 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and ARRDC3 expression is quantified. Does this perturbation result in a significant change in ARRDC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3028,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor ENSG00000070214 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000070214 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor SLC44A1 expression. Decide whether this perturbation leads to a significant alteration in SLC44A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2170,"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of ENSG00000140287 is measured. Does this perturbation cause a significant change in ENSG00000140287 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of HDC is measured. Does this perturbation cause a significant change in HDC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of ENSG00000206172 is measured. Determine whether ENSG00000206172 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of HBA1 is measured. Determine whether HBA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1638,"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor ENSG00000142945 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142945 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor KIF2C expression. Decide whether this perturbation leads to a significant alteration in KIF2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of ENSG00000250361. Does this perturbation cause a significant change in ENSG00000250361 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of GYPB. Does this perturbation cause a significant change in GYPB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of ENSG00000005187. Does perturbing ELMSAN1 lead to a significant change in ENSG00000005187 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of ACSM3. Does perturbing ELMSAN1 lead to a significant change in ACSM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and ENSG00000153012 expression is quantified. Does this perturbation result in a significant change in ENSG00000153012 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and LGI2 expression is quantified. Does this perturbation result in a significant change in LGI2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
76,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of ENSG00000113369 is measured. Determine whether ENSG00000113369 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of ARRDC3 is measured. Determine whether ARRDC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1480,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of ENSG00000240065 is measured. Does this perturbation cause a significant change in ENSG00000240065 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of PSMB9 is measured. Does this perturbation cause a significant change in PSMB9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of ENSG00000125144. Does perturbing BCORL1 lead to a significant change in ENSG00000125144 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of MT1G. Does perturbing BCORL1 lead to a significant change in MT1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and ENSG00000090238 expression is quantified. Does this perturbation result in a significant change in ENSG00000090238 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and YPEL3 expression is quantified. Does this perturbation result in a significant change in YPEL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and ENSG00000118058 expression is measured. Determine whether ENSG00000118058 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and KMT2A expression is measured. Determine whether KMT2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of ENSG00000137841. Does perturbing PLK4 lead to a significant change in ENSG00000137841 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of PLCB2. Does perturbing PLK4 lead to a significant change in PLCB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2290,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
27,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of ENSG00000077063 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of CTTNBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and ENSG00000135047 expression is measured. Determine whether ENSG00000135047 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and CTSL expression is measured. Determine whether CTSL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of ENSG00000183770 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of FOXL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2603,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and ENSG00000135047 expression is observed. Does this perturbation lead to a significant difference in ENSG00000135047 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and CTSL expression is observed. Does this perturbation lead to a significant difference in CTSL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of ENSG00000197766. Does perturbing NCL lead to a significant change in ENSG00000197766 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of CFD. Does perturbing NCL lead to a significant change in CFD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1690,"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of ENSG00000164687 is measured. Does this perturbation cause a significant change in ENSG00000164687 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of FABP5 is measured. Does this perturbation cause a significant change in FABP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of ENSG00000164687. Does this perturbation cause a significant change in ENSG00000164687 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of FABP5. Does this perturbation cause a significant change in FABP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and ENSG00000130829 expression is quantified. Does this perturbation result in a significant change in ENSG00000130829 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and DUSP9 expression is quantified. Does this perturbation result in a significant change in DUSP9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
17,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of ENSG00000106546 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of AHR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of ENSG00000158578. Does perturbing PRTG lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of ALAS2. Does perturbing PRTG lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of ENSG00000064886. Does perturbing TP73 lead to a significant change in ENSG00000064886 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of CHI3L2. Does perturbing TP73 lead to a significant change in CHI3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1870,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of ENSG00000204482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and ENSG00000069482 expression is quantified. Does this perturbation result in a significant change in ENSG00000069482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and GAL expression is quantified. Does this perturbation result in a significant change in GAL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in ENSG00000030110 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in BAK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of ENSG00000250361 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of GYPB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1778,"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor ENSG00000184384 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000184384 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor MAML2 expression. Decide whether this perturbation leads to a significant alteration in MAML2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of ENSG00000279576 is measured. Determine whether ENSG00000279576 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of AP000769.1 is measured. Determine whether AP000769.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of ENSG00000163499. Does perturbing FEV lead to a significant change in ENSG00000163499 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of CRYBA2. Does perturbing FEV lead to a significant change in CRYBA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2033,You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and ENSG00000114315 expression is observed. Does this perturbation lead to a significant difference in ENSG00000114315 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and HES1 expression is observed. Does this perturbation lead to a significant difference in HES1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of ENSG00000183019. Does this perturbation cause a significant change in ENSG00000183019 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of MCEMP1. Does this perturbation cause a significant change in MCEMP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of ENSG00000179111. Does this perturbation cause a significant change in ENSG00000179111 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of HES7. Does this perturbation cause a significant change in HES7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of ENSG00000130656. Does perturbing PRDM1 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of HBZ. Does perturbing PRDM1 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1543,You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and ENSG00000177606 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177606 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and JUN expression is observed. Does this perturbation lead to a significant difference in JUN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2950,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of ENSG00000160185 is measured. Does this perturbation cause a significant change in ENSG00000160185 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Does this perturbation cause a significant change in UBASH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of ENSG00000184697 is measured. Determine whether ENSG00000184697 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of CLDN6 is measured. Determine whether CLDN6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2323,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and ENSG00000182871 expression is observed. Does this perturbation lead to a significant difference in ENSG00000182871 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and COL18A1 expression is observed. Does this perturbation lead to a significant difference in COL18A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of ENSG00000184697. Does this perturbation cause a significant change in ENSG00000184697 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of CLDN6. Does this perturbation cause a significant change in CLDN6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and ENSG00000268621 expression is quantified. Does this perturbation result in a significant change in ENSG00000268621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
930,"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of ENSG00000157557 is measured. Does this perturbation cause a significant change in ENSG00000157557 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of ETS2 is measured. Does this perturbation cause a significant change in ETS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of ENSG00000064886. Does this perturbation cause a significant change in ENSG00000064886 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of CHI3L2. Does this perturbation cause a significant change in CHI3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of ENSG00000198758 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of EPS8L3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and ENSG00000104903 expression is measured. Determine whether ENSG00000104903 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and LYL1 expression is measured. Determine whether LYL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
788,"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor ENSG00000144655 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000144655 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor CSRNP1 expression. Decide whether this perturbation leads to a significant alteration in CSRNP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of ENSG00000129514 is measured. Determine whether ENSG00000129514 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of FOXA1 is measured. Determine whether FOXA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of ENSG00000105939 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of ZC3HAV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in ENSG00000117139 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in KDM5B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of ENSG00000273706. Does this perturbation cause a significant change in ENSG00000273706 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of LHX1. Does this perturbation cause a significant change in LHX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of ENSG00000011600. Does perturbing SPI1 lead to a significant change in ENSG00000011600 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of TYROBP. Does perturbing SPI1 lead to a significant change in TYROBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1738,"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor ENSG00000163497 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163497 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor FEV expression. Decide whether this perturbation leads to a significant alteration in FEV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in ENSG00000163499 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in CRYBA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and ENSG00000170180 expression is measured. Determine whether ENSG00000170180 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and GYPA expression is measured. Determine whether GYPA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of ENSG00000130303 is measured. Determine whether ENSG00000130303 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of BST2 is measured. Determine whether BST2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in ENSG00000125931 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in CITED1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of ENSG00000189171. Does perturbing NIT1 lead to a significant change in ENSG00000189171 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of S100A13. Does perturbing NIT1 lead to a significant change in S100A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and ENSG00000163499 expression is quantified. Does this perturbation result in a significant change in ENSG00000163499 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and CRYBA2 expression is quantified. Does this perturbation result in a significant change in CRYBA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and ENSG00000069482 expression is measured. Determine whether ENSG00000069482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and GAL expression is measured. Determine whether GAL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of ENSG00000117091. Does this perturbation cause a significant change in ENSG00000117091 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of CD48. Does this perturbation cause a significant change in CD48 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of ENSG00000206172 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of HBA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and ENSG00000103241 expression is quantified. Does this perturbation result in a significant change in ENSG00000103241 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and FOXF1 expression is quantified. Does this perturbation result in a significant change in FOXF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2620,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of ENSG00000162493 is measured. Does this perturbation cause a significant change in ENSG00000162493 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of PDPN is measured. Does this perturbation cause a significant change in PDPN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1630,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of ENSG00000142945 is measured. Does this perturbation cause a significant change in ENSG00000142945 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of KIF2C is measured. Does this perturbation cause a significant change in KIF2C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2143,You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and ENSG00000260793 expression is observed. Does this perturbation lead to a significant difference in ENSG00000260793 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and RP5-882C2.2 expression is observed. Does this perturbation lead to a significant difference in RP5-882C2.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2683,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of ENSG00000141753. Does this perturbation cause a significant change in ENSG00000141753 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of IGFBP4. Does this perturbation cause a significant change in IGFBP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1468,"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in ENSG00000120885 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in CLU expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
56,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of ENSG00000160838 is measured. Determine whether ENSG00000160838 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of LRRC71 is measured. Determine whether LRRC71 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1488,"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor ENSG00000240065 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000240065 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor PSMB9 expression. Decide whether this perturbation leads to a significant alteration in PSMB9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of ENSG00000064886. Does perturbing RREB1 lead to a significant change in ENSG00000064886 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of CHI3L2. Does perturbing RREB1 lead to a significant change in CHI3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of ENSG00000142945. Does perturbing KIF2C lead to a significant change in ENSG00000142945 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of KIF2C. Does perturbing KIF2C lead to a significant change in KIF2C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1463,You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of ENSG00000166450 is measured. Determine whether ENSG00000166450 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of PRTG is measured. Determine whether PRTG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of ENSG00000117091 is measured. Determine whether ENSG00000117091 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of CD48 is measured. Determine whether CD48 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1350,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of ENSG00000258274 is measured. Does this perturbation cause a significant change in ENSG00000258274 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of RP11-887P2.5 is measured. Does this perturbation cause a significant change in RP11-887P2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in ENSG00000184384 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in MAML2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in ENSG00000124762 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1138,"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor ENSG00000069482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000069482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor GAL expression. Decide whether this perturbation leads to a significant alteration in GAL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1243,You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and ENSG00000265972 expression is observed. Does this perturbation lead to a significant difference in ENSG00000265972 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in ENSG00000245848 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in CEBPA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
913,You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and ENSG00000156030 expression is observed. Does this perturbation lead to a significant difference in ENSG00000156030 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and ELMSAN1 expression is observed. Does this perturbation lead to a significant difference in ELMSAN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1090,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of ENSG00000103241 is measured. Does this perturbation cause a significant change in ENSG00000103241 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of FOXF1 is measured. Does this perturbation cause a significant change in FOXF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of ENSG00000166450. Does this perturbation cause a significant change in ENSG00000166450 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of PRTG. Does this perturbation cause a significant change in PRTG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and ENSG00000120738 expression is quantified. Does this perturbation result in a significant change in ENSG00000120738 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and EGR1 expression is quantified. Does this perturbation result in a significant change in EGR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of ENSG00000071967. Does perturbing IRF1 lead to a significant change in ENSG00000071967 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of CYBRD1. Does perturbing IRF1 lead to a significant change in CYBRD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
368,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor ENSG00000124762 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000124762 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
520,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of ENSG00000092067 is measured. Does this perturbation cause a significant change in ENSG00000092067 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of CEBPE is measured. Does this perturbation cause a significant change in CEBPE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of ENSG00000250361 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of GYPB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of ENSG00000166450. Does perturbing PRTG lead to a significant change in ENSG00000166450 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of PRTG. Does perturbing PRTG lead to a significant change in PRTG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
180,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of ENSG00000085185 is measured. Does this perturbation cause a significant change in ENSG00000085185 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of BCORL1 is measured. Does this perturbation cause a significant change in BCORL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and ENSG00000172331 expression is quantified. Does this perturbation result in a significant change in ENSG00000172331 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and BPGM expression is quantified. Does this perturbation result in a significant change in BPGM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in ENSG00000140287 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in HDC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of ENSG00000247516. Does this perturbation cause a significant change in ENSG00000247516 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of MIR4458HG. Does this perturbation cause a significant change in MIR4458HG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of ENSG00000177606 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of JUN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
240,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ENSG00000099625 is measured. Does this perturbation cause a significant change in ENSG00000099625 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of C19orf26 is measured. Does this perturbation cause a significant change in C19orf26 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of ENSG00000116871. Does this perturbation cause a significant change in ENSG00000116871 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of MAP7D1. Does this perturbation cause a significant change in MAP7D1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and ENSG00000245848 expression is quantified. Does this perturbation result in a significant change in ENSG00000245848 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and CEBPA expression is quantified. Does this perturbation result in a significant change in CEBPA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1663,You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and ENSG00000141744 expression is observed. Does this perturbation lead to a significant difference in ENSG00000141744 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and PNMT expression is observed. Does this perturbation lead to a significant difference in PNMT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1113,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and ENSG00000183770 expression is observed. Does this perturbation lead to a significant difference in ENSG00000183770 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and FOXL2 expression is observed. Does this perturbation lead to a significant difference in FOXL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of ENSG00000005187 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of ACSM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1353,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and ENSG00000258274 expression is observed. Does this perturbation lead to a significant difference in ENSG00000258274 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and RP11-887P2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-887P2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of ENSG00000103241. Does perturbing FOXF1 lead to a significant change in ENSG00000103241 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of FOXF1. Does perturbing FOXF1 lead to a significant change in FOXF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and ENSG00000184009 expression is quantified. Does this perturbation result in a significant change in ENSG00000184009 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and ACTG1 expression is quantified. Does this perturbation result in a significant change in ACTG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
543,You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and ENSG00000243449 expression is observed. Does this perturbation lead to a significant difference in ENSG00000243449 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and C4orf48 expression is observed. Does this perturbation lead to a significant difference in C4orf48 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of ENSG00000129514 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of FOXA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of ENSG00000169410 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of PTPN9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of ENSG00000166501. Does perturbing SET lead to a significant change in ENSG00000166501 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of PRKCB. Does perturbing SET lead to a significant change in PRKCB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and ENSG00000260793 expression is quantified. Does this perturbation result in a significant change in ENSG00000260793 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and RP5-882C2.2 expression is quantified. Does this perturbation result in a significant change in RP5-882C2.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and ENSG00000184697 expression is quantified. Does this perturbation result in a significant change in ENSG00000184697 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and CLDN6 expression is quantified. Does this perturbation result in a significant change in CLDN6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of ENSG00000129757 is measured. Determine whether ENSG00000129757 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of CDKN1C is measured. Determine whether CDKN1C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of ENSG00000108984. Does perturbing MAP2K6 lead to a significant change in ENSG00000108984 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of MAP2K6. Does perturbing MAP2K6 lead to a significant change in MAP2K6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and ENSG00000125931 expression is quantified. Does this perturbation result in a significant change in ENSG00000125931 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and CITED1 expression is quantified. Does this perturbation result in a significant change in CITED1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of ENSG00000125931 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of CITED1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of ENSG00000070087 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of PFN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in ENSG00000182871 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in COL18A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1793,You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and ENSG00000113594 expression is observed. Does this perturbation lead to a significant difference in ENSG00000113594 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and LIFR expression is observed. Does this perturbation lead to a significant difference in LIFR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of ENSG00000130656. Does perturbing CNN1 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of HBZ. Does perturbing CNN1 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and ENSG00000204482 expression is measured. Determine whether ENSG00000204482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1383,You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and ENSG00000188483 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188483 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and IER5L expression is observed. Does this perturbation lead to a significant difference in IER5L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and ENSG00000184384 expression is measured. Determine whether ENSG00000184384 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and MAML2 expression is measured. Determine whether MAML2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of ENSG00000196565 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of HBG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
653,You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and ENSG00000204482 expression is measured. Determine whether ENSG00000204482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2440,"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of ENSG00000079102 is measured. Does this perturbation cause a significant change in ENSG00000079102 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of RUNX1T1 is measured. Does this perturbation cause a significant change in RUNX1T1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of ENSG00000129514 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of FOXA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and ENSG00000111348 expression is measured. Determine whether ENSG00000111348 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and ARHGDIB expression is measured. Determine whether ARHGDIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of ENSG00000196517. Does perturbing SLC6A9 lead to a significant change in ENSG00000196517 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of SLC6A9. Does perturbing SLC6A9 lead to a significant change in SLC6A9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and ENSG00000115738 expression is quantified. Does this perturbation result in a significant change in ENSG00000115738 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and ID2 expression is quantified. Does this perturbation result in a significant change in ID2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2090,"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of ENSG00000158373 is measured. Does this perturbation cause a significant change in ENSG00000158373 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of HIST1H2BD is measured. Does this perturbation cause a significant change in HIST1H2BD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of ENSG00000090238. Does this perturbation cause a significant change in ENSG00000090238 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of YPEL3. Does this perturbation cause a significant change in YPEL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2470,"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of ENSG00000188536 is measured. Does this perturbation cause a significant change in ENSG00000188536 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of HBA2 is measured. Does this perturbation cause a significant change in HBA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1108,"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor ENSG00000189171 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000189171 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor S100A13 expression. Decide whether this perturbation leads to a significant alteration in S100A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
31,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of ENSG00000068078. Does perturbing ARID1A lead to a significant change in ENSG00000068078 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of FGFR3. Does perturbing ARID1A lead to a significant change in FGFR3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
793,You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
638,"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor ENSG00000184697 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000184697 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor CLDN6 expression. Decide whether this perturbation leads to a significant alteration in CLDN6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
91,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of ENSG00000158578. Does perturbing ATL1 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of ALAS2. Does perturbing ATL1 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of ENSG00000204472. Does perturbing MAPK1 lead to a significant change in ENSG00000204472 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of AIF1. Does perturbing MAPK1 lead to a significant change in AIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
728,"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor ENSG00000108821 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000108821 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor COL1A1 expression. Decide whether this perturbation leads to a significant alteration in COL1A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1473,You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and ENSG00000180785 expression is observed. Does this perturbation lead to a significant difference in ENSG00000180785 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and OR51E1 expression is observed. Does this perturbation lead to a significant difference in OR51E1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of ENSG00000184486. Does this perturbation cause a significant change in ENSG00000184486 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of POU3F2. Does this perturbation cause a significant change in POU3F2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in ENSG00000260793 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in RP5-882C2.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in ENSG00000185198 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
120,"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of ENSG00000273706 is measured. Does this perturbation cause a significant change in ENSG00000273706 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of LHX1 is measured. Does this perturbation cause a significant change in LHX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3090,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of ENSG00000105939 is measured. Does this perturbation cause a significant change in ENSG00000105939 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of ZC3HAV1 is measured. Does this perturbation cause a significant change in ZC3HAV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of ENSG00000005187. Does this perturbation cause a significant change in ENSG00000005187 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of ACSM3. Does this perturbation cause a significant change in ACSM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and ENSG00000070214 expression is quantified. Does this perturbation result in a significant change in ENSG00000070214 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and SLC44A1 expression is quantified. Does this perturbation result in a significant change in SLC44A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3048,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor ENSG00000189171 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000189171 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor S100A13 expression. Decide whether this perturbation leads to a significant alteration in S100A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
428,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in ENSG00000169413 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in RNASE6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and ENSG00000135409 expression is quantified. Does this perturbation result in a significant change in ENSG00000135409 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and AMHR2 expression is quantified. Does this perturbation result in a significant change in AMHR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and ENSG00000265972 expression is quantified. Does this perturbation result in a significant change in ENSG00000265972 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and ENSG00000174498 expression is quantified. Does this perturbation result in a significant change in ENSG00000174498 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and IGDCC3 expression is quantified. Does this perturbation result in a significant change in IGDCC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in ENSG00000102804 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in TSC22D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
948,"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor ENSG00000204472 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000204472 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor AIF1 expression. Decide whether this perturbation leads to a significant alteration in AIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
403,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and ENSG00000114315 expression is measured. Determine whether ENSG00000114315 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and HES1 expression is measured. Determine whether HES1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and ENSG00000115255 expression is measured. Determine whether ENSG00000115255 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and REEP6 expression is measured. Determine whether REEP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2188,"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor ENSG00000250361 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000250361 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor GYPB expression. Decide whether this perturbation leads to a significant alteration in GYPB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
528,"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor ENSG00000092067 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092067 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor CEBPE expression. Decide whether this perturbation leads to a significant alteration in CEBPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and ENSG00000196565 expression is measured. Determine whether ENSG00000196565 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and HBG2 expression is measured. Determine whether HBG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and ENSG00000121900 expression is quantified. Does this perturbation result in a significant change in ENSG00000121900 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and TMEM54 expression is quantified. Does this perturbation result in a significant change in TMEM54 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
943,You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and ENSG00000204472 expression is observed. Does this perturbation lead to a significant difference in ENSG00000204472 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and AIF1 expression is observed. Does this perturbation lead to a significant difference in AIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
198,"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor ENSG00000111057 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000111057 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor KRT18 expression. Decide whether this perturbation leads to a significant alteration in KRT18 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of ENSG00000118515. Does this perturbation cause a significant change in ENSG00000118515 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of SGK1. Does this perturbation cause a significant change in SGK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
100,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of ENSG00000141744. Does perturbing ISL2 lead to a significant change in ENSG00000141744 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of PNMT. Does perturbing ISL2 lead to a significant change in PNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
0,"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of ENSG00000134321 is measured. Does this perturbation cause a significant change in ENSG00000134321 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of RSAD2 is measured. Does this perturbation cause a significant change in RSAD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1840,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of ENSG00000108984 is measured. Does this perturbation cause a significant change in ENSG00000108984 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of MAP2K6 is measured. Does this perturbation cause a significant change in MAP2K6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of ENSG00000174498. Does this perturbation cause a significant change in ENSG00000174498 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of IGDCC3. Does this perturbation cause a significant change in IGDCC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1060,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of ENSG00000170608 is measured. Does this perturbation cause a significant change in ENSG00000170608 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of FOXA3 is measured. Does this perturbation cause a significant change in FOXA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and ENSG00000115844 expression is measured. Determine whether ENSG00000115844 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and DLX2 expression is measured. Determine whether DLX2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in ENSG00000105939 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in ZC3HAV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of ENSG00000188536 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of HBA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of ENSG00000169410. Does perturbing PTPN9 lead to a significant change in ENSG00000169410 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of PTPN9. Does perturbing PTPN9 lead to a significant change in PTPN9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and ENSG00000092067 expression is measured. Determine whether ENSG00000092067 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and CEBPE expression is measured. Determine whether CEBPE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of ENSG00000164920. Does this perturbation cause a significant change in ENSG00000164920 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of OSR2. Does this perturbation cause a significant change in OSR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of ENSG00000163513. Does this perturbation cause a significant change in ENSG00000163513 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of TGFBR2. Does this perturbation cause a significant change in TGFBR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
468,"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor ENSG00000119535 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000119535 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor CSF3R expression. Decide whether this perturbation leads to a significant alteration in CSF3R expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1450,"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of ENSG00000206172 is measured. Does this perturbation cause a significant change in ENSG00000206172 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of HBA1 is measured. Does this perturbation cause a significant change in HBA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and ENSG00000141753 expression is measured. Determine whether ENSG00000141753 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and IGFBP4 expression is measured. Determine whether IGFBP4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of ENSG00000111348. Does perturbing MAPK1 lead to a significant change in ENSG00000111348 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of ARHGDIB. Does perturbing MAPK1 lead to a significant change in ARHGDIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of ENSG00000164920. Does perturbing OSR2 lead to a significant change in ENSG00000164920 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of OSR2. Does perturbing OSR2 lead to a significant change in OSR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
62,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and ENSG00000268621 expression is quantified. Does this perturbation result in a significant change in ENSG00000268621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1880,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of ENSG00000135047 is measured. Does this perturbation cause a significant change in ENSG00000135047 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of CTSL is measured. Does this perturbation cause a significant change in CTSL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2708,"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor ENSG00000204482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000204482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of ENSG00000183019. Does perturbing BCL2L11 lead to a significant change in ENSG00000183019 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of MCEMP1. Does perturbing BCL2L11 lead to a significant change in MCEMP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and ENSG00000070087 expression is measured. Determine whether ENSG00000070087 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and PFN2 expression is measured. Determine whether PFN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of ENSG00000205542. Does perturbing TMSB4X lead to a significant change in ENSG00000205542 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of TMSB4X. Does perturbing TMSB4X lead to a significant change in TMSB4X expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of ENSG00000258274. Does perturbing HOXC13 lead to a significant change in ENSG00000258274 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of RP11-887P2.5. Does perturbing HOXC13 lead to a significant change in RP11-887P2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2990,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of ENSG00000185198 is measured. Does this perturbation cause a significant change in ENSG00000185198 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and ENSG00000163499 expression is measured. Determine whether ENSG00000163499 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and CRYBA2 expression is measured. Determine whether CRYBA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
768,"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor ENSG00000139219 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000139219 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor COL2A1 expression. Decide whether this perturbation leads to a significant alteration in COL2A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and ENSG00000163513 expression is measured. Determine whether ENSG00000163513 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and TGFBR2 expression is measured. Determine whether TGFBR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1453,You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and ENSG00000206172 expression is observed. Does this perturbation lead to a significant difference in ENSG00000206172 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and HBA1 expression is observed. Does this perturbation lead to a significant difference in HBA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of ENSG00000079102. Does perturbing RUNX1T1 lead to a significant change in ENSG00000079102 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of RUNX1T1. Does perturbing RUNX1T1 lead to a significant change in RUNX1T1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and ENSG00000184384 expression is quantified. Does this perturbation result in a significant change in ENSG00000184384 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and MAML2 expression is quantified. Does this perturbation result in a significant change in MAML2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and ENSG00000129757 expression is quantified. Does this perturbation result in a significant change in ENSG00000129757 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and CDKN1C expression is quantified. Does this perturbation result in a significant change in CDKN1C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and ENSG00000143162 expression is quantified. Does this perturbation result in a significant change in ENSG00000143162 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and CREG1 expression is quantified. Does this perturbation result in a significant change in CREG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
733,You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and ENSG00000168209 expression is observed. Does this perturbation lead to a significant difference in ENSG00000168209 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and DDIT4 expression is observed. Does this perturbation lead to a significant difference in DDIT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of ENSG00000119535. Does this perturbation cause a significant change in ENSG00000119535 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of CSF3R. Does this perturbation cause a significant change in CSF3R expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2770,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of ENSG00000121900 is measured. Does this perturbation cause a significant change in ENSG00000121900 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of TMEM54 is measured. Does this perturbation cause a significant change in TMEM54 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1313,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and ENSG00000258274 expression is observed. Does this perturbation lead to a significant difference in ENSG00000258274 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and RP11-887P2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-887P2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in ENSG00000166340 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in TPP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2568,"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor ENSG00000119535 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000119535 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor CSF3R expression. Decide whether this perturbation leads to a significant alteration in CSF3R expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2308,"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor ENSG00000143369 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143369 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor ECM1 expression. Decide whether this perturbation leads to a significant alteration in ECM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of ENSG00000064886. Does this perturbation cause a significant change in ENSG00000064886 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of CHI3L2. Does this perturbation cause a significant change in CHI3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
418,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor ENSG00000129757 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000129757 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor CDKN1C expression. Decide whether this perturbation leads to a significant alteration in CDKN1C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1830,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of ENSG00000108984 is measured. Does this perturbation cause a significant change in ENSG00000108984 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of MAP2K6 is measured. Does this perturbation cause a significant change in MAP2K6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of ENSG00000265972. Does this perturbation cause a significant change in ENSG00000265972 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and ENSG00000166450 expression is measured. Determine whether ENSG00000166450 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and PRTG expression is measured. Determine whether PRTG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of ENSG00000213934 is measured. Determine whether ENSG00000213934 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of HBG1 is measured. Determine whether HBG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ENSG00000158578. Does perturbing C19orf26 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ALAS2. Does perturbing C19orf26 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1030,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of ENSG00000129514 is measured. Does this perturbation cause a significant change in ENSG00000129514 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of FOXA1 is measured. Does this perturbation cause a significant change in FOXA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of ENSG00000004939. Does this perturbation cause a significant change in ENSG00000004939 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of SLC4A1. Does this perturbation cause a significant change in SLC4A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of ENSG00000160185. Does this perturbation cause a significant change in ENSG00000160185 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of UBASH3A. Does this perturbation cause a significant change in UBASH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1220,"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of ENSG00000105223 is measured. Does this perturbation cause a significant change in ENSG00000105223 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of PLD3 is measured. Does this perturbation cause a significant change in PLD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of ENSG00000077063 is measured. Determine whether ENSG00000077063 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of CTTNBP2 is measured. Determine whether CTTNBP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of ENSG00000119535. Does perturbing CEBPA lead to a significant change in ENSG00000119535 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of CSF3R. Does perturbing CEBPA lead to a significant change in CSF3R expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and ENSG00000184481 expression is measured. Determine whether ENSG00000184481 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and FOXO4 expression is measured. Determine whether FOXO4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of ENSG00000069482. Does this perturbation cause a significant change in ENSG00000069482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of GAL. Does this perturbation cause a significant change in GAL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of ENSG00000279669. Does perturbing SNAI1 lead to a significant change in ENSG00000279669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of RP11-717F1.1. Does perturbing SNAI1 lead to a significant change in RP11-717F1.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
803,You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and ENSG00000100097 expression is observed. Does this perturbation lead to a significant difference in ENSG00000100097 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and LGALS1 expression is observed. Does this perturbation lead to a significant difference in LGALS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
540,"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of ENSG00000243449 is measured. Does this perturbation cause a significant change in ENSG00000243449 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of C4orf48 is measured. Does this perturbation cause a significant change in C4orf48 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in ENSG00000183770 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in FOXL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in ENSG00000120738 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in EGR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of ENSG00000104903 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of LYL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of ENSG00000116871. Does perturbing MAP7D1 lead to a significant change in ENSG00000116871 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of MAP7D1. Does perturbing MAP7D1 lead to a significant change in MAP7D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of ENSG00000204482. Does this perturbation cause a significant change in ENSG00000204482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1720,"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of ENSG00000277268 is measured. Does this perturbation cause a significant change in ENSG00000277268 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of RP11-445F12.1 is measured. Does this perturbation cause a significant change in RP11-445F12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of ENSG00000120885 is measured. Determine whether ENSG00000120885 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of CLU is measured. Determine whether CLU shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of ENSG00000141744 is measured. Determine whether ENSG00000141744 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of PNMT is measured. Determine whether PNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of ENSG00000268621 is measured. Determine whether ENSG00000268621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of ENSG00000154127 is measured. Determine whether ENSG00000154127 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of UBASH3B is measured. Determine whether UBASH3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2268,"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor ENSG00000185198 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000185198 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1790,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of ENSG00000113594 is measured. Does this perturbation cause a significant change in ENSG00000113594 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of LIFR is measured. Does this perturbation cause a significant change in LIFR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of ENSG00000070214. Does this perturbation cause a significant change in ENSG00000070214 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of SLC44A1. Does this perturbation cause a significant change in SLC44A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of ENSG00000143498. Does this perturbation cause a significant change in ENSG00000143498 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of TAF1A. Does this perturbation cause a significant change in TAF1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of ENSG00000183770 is measured. Determine whether ENSG00000183770 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of FOXL2 is measured. Determine whether FOXL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in ENSG00000177606 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in JUN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in ENSG00000277268 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in RP11-445F12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1190,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of ENSG00000109099 is measured. Does this perturbation cause a significant change in ENSG00000109099 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of PMP22 is measured. Does this perturbation cause a significant change in PMP22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in ENSG00000154127 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in UBASH3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of ENSG00000272211 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of RP11-347P5.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
81,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of ENSG00000115758. Does perturbing ARRDC3 lead to a significant change in ENSG00000115758 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of ODC1. Does perturbing ARRDC3 lead to a significant change in ODC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and ENSG00000005187 expression is quantified. Does this perturbation result in a significant change in ENSG00000005187 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and ACSM3 expression is quantified. Does this perturbation result in a significant change in ACSM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of ENSG00000129757. Does this perturbation cause a significant change in ENSG00000129757 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of CDKN1C. Does this perturbation cause a significant change in CDKN1C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of ENSG00000102575 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of ACP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of ENSG00000135111. Does this perturbation cause a significant change in ENSG00000135111 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of TBX3. Does this perturbation cause a significant change in TBX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1363,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and ENSG00000258274 expression is observed. Does this perturbation lead to a significant difference in ENSG00000258274 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and RP11-887P2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-887P2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2078,"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor ENSG00000189171 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000189171 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor S100A13 expression. Decide whether this perturbation leads to a significant alteration in S100A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of ENSG00000142945 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of KIF2C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in ENSG00000070214 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in SLC44A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2513,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and ENSG00000185198 expression is observed. Does this perturbation lead to a significant difference in ENSG00000185198 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and ENSG00000119969 expression is measured. Determine whether ENSG00000119969 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and HELLS expression is measured. Determine whether HELLS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of ENSG00000004939. Does perturbing SLC4A1 lead to a significant change in ENSG00000004939 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of SLC4A1. Does perturbing SLC4A1 lead to a significant change in SLC4A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and ENSG00000143498 expression is quantified. Does this perturbation result in a significant change in ENSG00000143498 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and TAF1A expression is quantified. Does this perturbation result in a significant change in TAF1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
24,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of ENSG00000077063. Does this perturbation cause a significant change in ENSG00000077063 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of CTTNBP2. Does this perturbation cause a significant change in CTTNBP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and ENSG00000004939 expression is measured. Determine whether ENSG00000004939 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and SLC4A1 expression is measured. Determine whether SLC4A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of ENSG00000177606. Does perturbing JUN lead to a significant change in ENSG00000177606 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of JUN. Does perturbing JUN lead to a significant change in JUN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of ENSG00000070214 is measured. Determine whether ENSG00000070214 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of SLC44A1 is measured. Determine whether SLC44A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
748,"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and ENSG00000143369 expression is measured. Determine whether ENSG00000143369 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and ECM1 expression is measured. Determine whether ECM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1908,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of ENSG00000118058. Does perturbing KMT2A lead to a significant change in ENSG00000118058 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of KMT2A. Does perturbing KMT2A lead to a significant change in KMT2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1338,"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor ENSG00000170689 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000170689 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor HOXB9 expression. Decide whether this perturbation leads to a significant alteration in HOXB9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of ENSG00000153012 is measured. Determine whether ENSG00000153012 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of LGI2 is measured. Determine whether LGI2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2763,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and ENSG00000121900 expression is observed. Does this perturbation lead to a significant difference in ENSG00000121900 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and TMEM54 expression is observed. Does this perturbation lead to a significant difference in TMEM54 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and ENSG00000135409 expression is measured. Determine whether ENSG00000135409 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and AMHR2 expression is measured. Determine whether AMHR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of ENSG00000254614 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of AP003068.23 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of ENSG00000070087. Does perturbing CEBPB lead to a significant change in ENSG00000070087 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of PFN2. Does perturbing CEBPB lead to a significant change in PFN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in ENSG00000266976 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in AC079466.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of ENSG00000186185. Does this perturbation cause a significant change in ENSG00000186185 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of KIF18B. Does this perturbation cause a significant change in KIF18B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in ENSG00000119535 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in CSF3R expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of ENSG00000090382. Does this perturbation cause a significant change in ENSG00000090382 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of LYZ. Does this perturbation cause a significant change in LYZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1158,"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor ENSG00000166340 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000166340 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor TPP1 expression. Decide whether this perturbation leads to a significant alteration in TPP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1398,"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor ENSG00000188483 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188483 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor IER5L expression. Decide whether this perturbation leads to a significant alteration in IER5L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2580,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of ENSG00000134294 is measured. Does this perturbation cause a significant change in ENSG00000134294 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of SLC38A2 is measured. Does this perturbation cause a significant change in SLC38A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2010,"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of ENSG00000115738 is measured. Does this perturbation cause a significant change in ENSG00000115738 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of ID2 is measured. Does this perturbation cause a significant change in ID2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in ENSG00000130303 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in BST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of ENSG00000245848 is measured. Determine whether ENSG00000245848 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of CEBPA is measured. Determine whether CEBPA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in ENSG00000184481 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in FOXO4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and ENSG00000102804 expression is quantified. Does this perturbation result in a significant change in ENSG00000102804 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and TSC22D1 expression is quantified. Does this perturbation result in a significant change in TSC22D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of ENSG00000180785 is measured. Determine whether ENSG00000180785 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of OR51E1 is measured. Determine whether OR51E1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
383,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of ENSG00000105223. Does this perturbation cause a significant change in ENSG00000105223 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of PLD3. Does this perturbation cause a significant change in PLD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of ENSG00000119969. Does this perturbation cause a significant change in ENSG00000119969 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of HELLS. Does this perturbation cause a significant change in HELLS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of ENSG00000030110 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of BAK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2703,You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and ENSG00000204482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000204482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ENSG00000099625 is measured. Determine whether ENSG00000099625 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of C19orf26 is measured. Determine whether C19orf26 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2940,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of ENSG00000160185 is measured. Does this perturbation cause a significant change in ENSG00000160185 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Does this perturbation cause a significant change in UBASH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2643,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and ENSG00000196517 expression is observed. Does this perturbation lead to a significant difference in ENSG00000196517 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and SLC6A9 expression is observed. Does this perturbation lead to a significant difference in SLC6A9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of ENSG00000184384 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of MAML2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1843,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and ENSG00000108984 expression is observed. Does this perturbation lead to a significant difference in ENSG00000108984 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and MAP2K6 expression is observed. Does this perturbation lead to a significant difference in MAP2K6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and ENSG00000002586 expression is quantified. Does this perturbation result in a significant change in ENSG00000002586 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and CD99 expression is quantified. Does this perturbation result in a significant change in CD99 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and ENSG00000140545 expression is quantified. Does this perturbation result in a significant change in ENSG00000140545 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and MFGE8 expression is quantified. Does this perturbation result in a significant change in MFGE8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in ENSG00000119535 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in CSF3R expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and ENSG00000250361 expression is quantified. Does this perturbation result in a significant change in ENSG00000250361 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and GYPB expression is quantified. Does this perturbation result in a significant change in GYPB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and ENSG00000129757 expression is measured. Determine whether ENSG00000129757 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and CDKN1C expression is measured. Determine whether CDKN1C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and ENSG00000245848 expression is measured. Determine whether ENSG00000245848 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and CEBPA expression is measured. Determine whether CEBPA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2130,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of ENSG00000137841 is measured. Does this perturbation cause a significant change in ENSG00000137841 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of PLCB2 is measured. Does this perturbation cause a significant change in PLCB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in ENSG00000103241 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in FOXF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1303,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and ENSG00000117091 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117091 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and CD48 expression is observed. Does this perturbation lead to a significant difference in CD48 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ENSG00000099625 expression is quantified. Does this perturbation result in a significant change in ENSG00000099625 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and C19orf26 expression is quantified. Does this perturbation result in a significant change in C19orf26 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of ENSG00000268621. Does perturbing ZC3HAV1 lead to a significant change in ENSG00000268621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of AC006262.5. Does perturbing ZC3HAV1 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ENSG00000099625 is measured. Determine whether ENSG00000099625 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of C19orf26 is measured. Determine whether C19orf26 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2833,You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and ENSG00000163513 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163513 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and TGFBR2 expression is observed. Does this perturbation lead to a significant difference in TGFBR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
83,You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and ENSG00000115758 expression is observed. Does this perturbation lead to a significant difference in ENSG00000115758 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and ODC1 expression is observed. Does this perturbation lead to a significant difference in ODC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
148,"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor ENSG00000030110 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000030110 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor BAK1 expression. Decide whether this perturbation leads to a significant alteration in BAK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in ENSG00000170180 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in GYPA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in ENSG00000183019 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in MCEMP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1498,"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor ENSG00000071967 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000071967 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor CYBRD1 expression. Decide whether this perturbation leads to a significant alteration in CYBRD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2803,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and ENSG00000101200 expression is observed. Does this perturbation lead to a significant difference in ENSG00000101200 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and AVP expression is observed. Does this perturbation lead to a significant difference in AVP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of ENSG00000070214. Does perturbing GLB1L2 lead to a significant change in ENSG00000070214 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of SLC44A1. Does perturbing GLB1L2 lead to a significant change in SLC44A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1680,"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of ENSG00000118058 is measured. Does this perturbation cause a significant change in ENSG00000118058 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of KMT2A is measured. Does this perturbation cause a significant change in KMT2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and ENSG00000111348 expression is quantified. Does this perturbation result in a significant change in ENSG00000111348 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and ARHGDIB expression is quantified. Does this perturbation result in a significant change in ARHGDIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1103,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and ENSG00000189171 expression is observed. Does this perturbation lead to a significant difference in ENSG00000189171 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and S100A13 expression is observed. Does this perturbation lead to a significant difference in S100A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in ENSG00000154127 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in UBASH3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of ENSG00000170608. Does this perturbation cause a significant change in ENSG00000170608 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of FOXA3. Does this perturbation cause a significant change in FOXA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1358,"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor ENSG00000258274 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000258274 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor RP11-887P2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-887P2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
110,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of ENSG00000250361 is measured. Does this perturbation cause a significant change in ENSG00000250361 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of GYPB is measured. Does this perturbation cause a significant change in GYPB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1273,You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and ENSG00000196188 expression is observed. Does this perturbation lead to a significant difference in ENSG00000196188 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and CTSE expression is observed. Does this perturbation lead to a significant difference in CTSE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1803,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and ENSG00000034152 expression is observed. Does this perturbation lead to a significant difference in ENSG00000034152 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and MAP2K3 expression is observed. Does this perturbation lead to a significant difference in MAP2K3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and ENSG00000120738 expression is measured. Determine whether ENSG00000120738 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and EGR1 expression is measured. Determine whether EGR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1020,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of ENSG00000129514 is measured. Does this perturbation cause a significant change in ENSG00000129514 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of FOXA1 is measured. Does this perturbation cause a significant change in FOXA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2838,"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor ENSG00000163513 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163513 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor TGFBR2 expression. Decide whether this perturbation leads to a significant alteration in TGFBR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of ENSG00000153094. Does this perturbation cause a significant change in ENSG00000153094 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of BCL2L11. Does this perturbation cause a significant change in BCL2L11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of ENSG00000115844 is measured. Determine whether ENSG00000115844 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of DLX2 is measured. Determine whether DLX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of ENSG00000090382 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of LYZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of ENSG00000158578. Does perturbing CDKN1B lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of ALAS2. Does perturbing CDKN1B lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1408,"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
850,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of ENSG00000108984. Does perturbing MAP2K6 lead to a significant change in ENSG00000108984 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of MAP2K6. Does perturbing MAP2K6 lead to a significant change in MAP2K6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of ENSG00000153012 is measured. Determine whether ENSG00000153012 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of LGI2 is measured. Determine whether LGI2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3008,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor ENSG00000118777 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000118777 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor ABCG2 expression. Decide whether this perturbation leads to a significant alteration in ABCG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of ENSG00000204472. Does perturbing ETS2 lead to a significant change in ENSG00000204472 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of AIF1. Does perturbing ETS2 lead to a significant change in AIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3060,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of ENSG00000247516 is measured. Does this perturbation cause a significant change in ENSG00000247516 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of MIR4458HG is measured. Does this perturbation cause a significant change in MIR4458HG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of ENSG00000123473 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of STIL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in ENSG00000164920 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in OSR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1208,"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor ENSG00000179111 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000179111 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor HES7 expression. Decide whether this perturbation leads to a significant alteration in HES7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
6,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of ENSG00000134321 is measured. Determine whether ENSG00000134321 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of RSAD2 is measured. Determine whether RSAD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of ENSG00000163497. Does perturbing LHX1 lead to a significant change in ENSG00000163497 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of FEV. Does perturbing LHX1 lead to a significant change in FEV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of ENSG00000245532. Does this perturbation cause a significant change in ENSG00000245532 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of NEAT1. Does this perturbation cause a significant change in NEAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of ENSG00000180785 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of OR51E1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and ENSG00000069482 expression is quantified. Does this perturbation result in a significant change in ENSG00000069482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and GAL expression is quantified. Does this perturbation result in a significant change in GAL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of ENSG00000130829 is measured. Determine whether ENSG00000130829 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of DUSP9 is measured. Determine whether DUSP9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of ENSG00000079102 is measured. Determine whether ENSG00000079102 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of RUNX1T1 is measured. Determine whether RUNX1T1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and ENSG00000231312 expression is quantified. Does this perturbation result in a significant change in ENSG00000231312 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and AC007246.3 expression is quantified. Does this perturbation result in a significant change in AC007246.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and ENSG00000090382 expression is measured. Determine whether ENSG00000090382 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and LYZ expression is measured. Determine whether LYZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1520,"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of ENSG00000141744 is measured. Does this perturbation cause a significant change in ENSG00000141744 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of PNMT is measured. Does this perturbation cause a significant change in PNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and ENSG00000206172 expression is quantified. Does this perturbation result in a significant change in ENSG00000206172 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and HBA1 expression is quantified. Does this perturbation result in a significant change in HBA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of ENSG00000069535 is measured. Determine whether ENSG00000069535 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of MAOB is measured. Determine whether MAOB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1683,You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and ENSG00000118058 expression is observed. Does this perturbation lead to a significant difference in ENSG00000118058 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and KMT2A expression is observed. Does this perturbation lead to a significant difference in KMT2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
253,You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ENSG00000099625 expression is observed. Does this perturbation lead to a significant difference in ENSG00000099625 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and C19orf26 expression is observed. Does this perturbation lead to a significant difference in C19orf26 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of ENSG00000227053. Does this perturbation cause a significant change in ENSG00000227053 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of RP11-395B7.4. Does this perturbation cause a significant change in RP11-395B7.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and ENSG00000141753 expression is quantified. Does this perturbation result in a significant change in ENSG00000141753 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and IGFBP4 expression is quantified. Does this perturbation result in a significant change in IGFBP4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and ENSG00000184697 expression is measured. Determine whether ENSG00000184697 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and CLDN6 expression is measured. Determine whether CLDN6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in ENSG00000166450 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in PRTG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of ENSG00000245532 is measured. Determine whether ENSG00000245532 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of NEAT1 is measured. Determine whether NEAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and ENSG00000250361 expression is measured. Determine whether ENSG00000250361 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and GYPB expression is measured. Determine whether GYPB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and ENSG00000120885 expression is measured. Determine whether ENSG00000120885 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and CLU expression is measured. Determine whether CLU exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of ENSG00000245848. Does perturbing CELF2 lead to a significant change in ENSG00000245848 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of CEBPA. Does perturbing CELF2 lead to a significant change in CEBPA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of ENSG00000105697 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of HAMP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of ENSG00000103241. Does perturbing FOXF1 lead to a significant change in ENSG00000103241 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of FOXF1. Does perturbing FOXF1 lead to a significant change in FOXF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of ENSG00000188536. Does perturbing S1PR2 lead to a significant change in ENSG00000188536 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of HBA2. Does perturbing S1PR2 lead to a significant change in HBA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of ENSG00000273706 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of LHX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and ENSG00000204472 expression is quantified. Does this perturbation result in a significant change in ENSG00000204472 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and AIF1 expression is quantified. Does this perturbation result in a significant change in AIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1523,You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and ENSG00000141744 expression is observed. Does this perturbation lead to a significant difference in ENSG00000141744 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and PNMT expression is observed. Does this perturbation lead to a significant difference in PNMT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of ENSG00000189171 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of S100A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
203,You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and ENSG00000125144 expression is observed. Does this perturbation lead to a significant difference in ENSG00000125144 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and MT1G expression is observed. Does this perturbation lead to a significant difference in MT1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
588,"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor ENSG00000119535 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000119535 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor CSF3R expression. Decide whether this perturbation leads to a significant alteration in CSF3R expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of ENSG00000204482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of ENSG00000279529. Does this perturbation cause a significant change in ENSG00000279529 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of CTD-3222D19.8. Does this perturbation cause a significant change in CTD-3222D19.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
333,You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and ENSG00000002586 expression is observed. Does this perturbation lead to a significant difference in ENSG00000002586 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and CD99 expression is observed. Does this perturbation lead to a significant difference in CD99 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in ENSG00000185198 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of ENSG00000121900 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of TMEM54 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
63,You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and ENSG00000268621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000268621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1850,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of ENSG00000266976 is measured. Does this perturbation cause a significant change in ENSG00000266976 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of AC079466.1 is measured. Does this perturbation cause a significant change in AC079466.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of ENSG00000120738 is measured. Determine whether ENSG00000120738 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of EGR1 is measured. Determine whether EGR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and ENSG00000064886 expression is quantified. Does this perturbation result in a significant change in ENSG00000064886 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and CHI3L2 expression is quantified. Does this perturbation result in a significant change in CHI3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and ENSG00000139219 expression is measured. Determine whether ENSG00000139219 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and COL2A1 expression is measured. Determine whether COL2A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
313,You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and ENSG00000196565 expression is observed. Does this perturbation lead to a significant difference in ENSG00000196565 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and HBG2 expression is observed. Does this perturbation lead to a significant difference in HBG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of ENSG00000204482. Does perturbing CELF2 lead to a significant change in ENSG00000204482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of LST1. Does perturbing CELF2 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and ENSG00000105610 expression is quantified. Does this perturbation result in a significant change in ENSG00000105610 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and KLF1 expression is quantified. Does this perturbation result in a significant change in KLF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and ENSG00000143674 expression is measured. Determine whether ENSG00000143674 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and KIAA1804 expression is measured. Determine whether KIAA1804 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2773,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and ENSG00000121900 expression is observed. Does this perturbation lead to a significant difference in ENSG00000121900 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and TMEM54 expression is observed. Does this perturbation lead to a significant difference in TMEM54 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of ENSG00000123473 is measured. Determine whether ENSG00000123473 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of STIL is measured. Determine whether STIL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and ENSG00000188536 expression is quantified. Does this perturbation result in a significant change in ENSG00000188536 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and HBA2 expression is quantified. Does this perturbation result in a significant change in HBA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in ENSG00000188536 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in HBA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in ENSG00000174498 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in IGDCC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of ENSG00000130829. Does this perturbation cause a significant change in ENSG00000130829 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of DUSP9. Does this perturbation cause a significant change in DUSP9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of ENSG00000188483 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of IER5L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of ENSG00000115844 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of DLX2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
880,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2743,You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and ENSG00000123473 expression is observed. Does this perturbation lead to a significant difference in ENSG00000123473 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and STIL expression is observed. Does this perturbation lead to a significant difference in STIL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and ENSG00000250361 expression is measured. Determine whether ENSG00000250361 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and GYPB expression is measured. Determine whether GYPB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2598,"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor ENSG00000268621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000268621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of ENSG00000163497 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of FEV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1118,"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor ENSG00000183770 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000183770 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor FOXL2 expression. Decide whether this perturbation leads to a significant alteration in FOXL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
393,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and ENSG00000141753 expression is observed. Does this perturbation lead to a significant difference in ENSG00000141753 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and IGFBP4 expression is observed. Does this perturbation lead to a significant difference in IGFBP4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and ENSG00000110492 expression is quantified. Does this perturbation result in a significant change in ENSG00000110492 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and MDK expression is quantified. Does this perturbation result in a significant change in MDK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2608,"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor ENSG00000135047 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000135047 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor CTSL expression. Decide whether this perturbation leads to a significant alteration in CTSL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1518,"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor ENSG00000141744 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000141744 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor PNMT expression. Decide whether this perturbation leads to a significant alteration in PNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of ENSG00000026297. Does perturbing DLX2 lead to a significant change in ENSG00000026297 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of RNASET2. Does perturbing DLX2 lead to a significant change in RNASET2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of ENSG00000102804. Does perturbing C3orf72 lead to a significant change in ENSG00000102804 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of TSC22D1. Does perturbing C3orf72 lead to a significant change in TSC22D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and ENSG00000206172 expression is measured. Determine whether ENSG00000206172 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and HBA1 expression is measured. Determine whether HBA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and ENSG00000170608 expression is quantified. Does this perturbation result in a significant change in ENSG00000170608 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and FOXA3 expression is quantified. Does this perturbation result in a significant change in FOXA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of ENSG00000135047 is measured. Determine whether ENSG00000135047 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of CTSL is measured. Determine whether CTSL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
830,"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of ENSG00000026297 is measured. Does this perturbation cause a significant change in ENSG00000026297 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of RNASET2 is measured. Does this perturbation cause a significant change in RNASET2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of ENSG00000196565. Does perturbing CBFA2T3 lead to a significant change in ENSG00000196565 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of HBG2. Does perturbing CBFA2T3 lead to a significant change in HBG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2918,"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor ENSG00000102804 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000102804 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor TSC22D1 expression. Decide whether this perturbation leads to a significant alteration in TSC22D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and ENSG00000069011 expression is quantified. Does this perturbation result in a significant change in ENSG00000069011 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and PITX1 expression is quantified. Does this perturbation result in a significant change in PITX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2723,You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and ENSG00000011600 expression is observed. Does this perturbation lead to a significant difference in ENSG00000011600 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and TYROBP expression is observed. Does this perturbation lead to a significant difference in TYROBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1600,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of ENSG00000186185 is measured. Does this perturbation cause a significant change in ENSG00000186185 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of KIF18B is measured. Does this perturbation cause a significant change in KIF18B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
573,You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and ENSG00000125931 expression is observed. Does this perturbation lead to a significant difference in ENSG00000125931 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and CITED1 expression is observed. Does this perturbation lead to a significant difference in CITED1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in ENSG00000103241 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in FOXF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of ENSG00000268621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
823,You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and ENSG00000115844 expression is observed. Does this perturbation lead to a significant difference in ENSG00000115844 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and DLX2 expression is observed. Does this perturbation lead to a significant difference in DLX2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1978,"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor ENSG00000111348 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000111348 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor ARHGDIB expression. Decide whether this perturbation leads to a significant alteration in ARHGDIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1493,You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and ENSG00000071967 expression is observed. Does this perturbation lead to a significant difference in ENSG00000071967 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and CYBRD1 expression is observed. Does this perturbation lead to a significant difference in CYBRD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of ENSG00000197965 is measured. Determine whether ENSG00000197965 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of MPZL1 is measured. Determine whether MPZL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
813,You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and ENSG00000115844 expression is observed. Does this perturbation lead to a significant difference in ENSG00000115844 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and DLX2 expression is observed. Does this perturbation lead to a significant difference in DLX2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of ENSG00000247516 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of MIR4458HG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and ENSG00000140287 expression is quantified. Does this perturbation result in a significant change in ENSG00000140287 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and HDC expression is quantified. Does this perturbation result in a significant change in HDC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of ENSG00000273706 is measured. Determine whether ENSG00000273706 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of LHX1 is measured. Determine whether LHX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2778,"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor ENSG00000121900 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000121900 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor TMEM54 expression. Decide whether this perturbation leads to a significant alteration in TMEM54 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and ENSG00000182871 expression is measured. Determine whether ENSG00000182871 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and COL18A1 expression is measured. Determine whether COL18A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2043,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and ENSG00000115053 expression is observed. Does this perturbation lead to a significant difference in ENSG00000115053 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and NCL expression is observed. Does this perturbation lead to a significant difference in NCL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of ENSG00000243449 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of C4orf48 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of ENSG00000135409 is measured. Determine whether ENSG00000135409 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of AMHR2 is measured. Determine whether AMHR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1640,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of ENSG00000279529 is measured. Does this perturbation cause a significant change in ENSG00000279529 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of CTD-3222D19.8 is measured. Does this perturbation cause a significant change in CTD-3222D19.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of ENSG00000142669. Does perturbing FOSB lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of SH3BGRL3. Does perturbing FOSB lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
568,"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor ENSG00000204482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000204482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1298,"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor ENSG00000106031 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000106031 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor HOXA13 expression. Decide whether this perturbation leads to a significant alteration in HOXA13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of ENSG00000144655. Does this perturbation cause a significant change in ENSG00000144655 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of CSRNP1. Does this perturbation cause a significant change in CSRNP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of ENSG00000030110. Does perturbing BAK1 lead to a significant change in ENSG00000030110 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of BAK1. Does perturbing BAK1 lead to a significant change in BAK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2618,"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor ENSG00000254614 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000254614 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor AP003068.23 expression. Decide whether this perturbation leads to a significant alteration in AP003068.23 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and ENSG00000030110 expression is measured. Determine whether ENSG00000030110 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and BAK1 expression is measured. Determine whether BAK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of ENSG00000141753 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of IGFBP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
578,"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor ENSG00000125931 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000125931 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor CITED1 expression. Decide whether this perturbation leads to a significant alteration in CITED1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of ENSG00000106991. Does this perturbation cause a significant change in ENSG00000106991 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of ENG. Does this perturbation cause a significant change in ENG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of ENSG00000180785. Does this perturbation cause a significant change in ENSG00000180785 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of OR51E1. Does this perturbation cause a significant change in OR51E1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in ENSG00000258274 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in RP11-887P2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of ENSG00000188483 is measured. Determine whether ENSG00000188483 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of IER5L is measured. Determine whether IER5L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2810,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of ENSG00000135111 is measured. Does this perturbation cause a significant change in ENSG00000135111 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of TBX3 is measured. Does this perturbation cause a significant change in TBX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of ENSG00000026297 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of RNASET2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of ENSG00000237330. Does this perturbation cause a significant change in ENSG00000237330 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of RNF223. Does this perturbation cause a significant change in RNF223 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of ENSG00000100097. Does perturbing CSRNP1 lead to a significant change in ENSG00000100097 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of LGALS1. Does perturbing CSRNP1 lead to a significant change in LGALS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3120,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of ENSG00000227053 is measured. Does this perturbation cause a significant change in ENSG00000227053 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of RP11-395B7.4 is measured. Does this perturbation cause a significant change in RP11-395B7.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of ENSG00000163513 is measured. Determine whether ENSG00000163513 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of TGFBR2 is measured. Determine whether TGFBR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of ENSG00000005187. Does perturbing KIAA1804 lead to a significant change in ENSG00000005187 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of ACSM3. Does perturbing KIAA1804 lead to a significant change in ACSM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and ENSG00000121068 expression is measured. Determine whether ENSG00000121068 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and TBX2 expression is measured. Determine whether TBX2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and ENSG00000158373 expression is quantified. Does this perturbation result in a significant change in ENSG00000158373 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and HIST1H2BD expression is quantified. Does this perturbation result in a significant change in HIST1H2BD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and ENSG00000130176 expression is measured. Determine whether ENSG00000130176 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and CNN1 expression is measured. Determine whether CNN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of ENSG00000115844. Does perturbing DLX2 lead to a significant change in ENSG00000115844 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of DLX2. Does perturbing DLX2 lead to a significant change in DLX2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of ENSG00000169413. Does perturbing MAP4K5 lead to a significant change in ENSG00000169413 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of RNASE6. Does perturbing MAP4K5 lead to a significant change in RNASE6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of ENSG00000101200 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of AVP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in ENSG00000077063 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in CTTNBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and ENSG00000188536 expression is measured. Determine whether ENSG00000188536 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and HBA2 expression is measured. Determine whether HBA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of ENSG00000247516. Does this perturbation cause a significant change in ENSG00000247516 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of MIR4458HG. Does this perturbation cause a significant change in MIR4458HG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of ENSG00000260793 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of RP5-882C2.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of ENSG00000141744. Does this perturbation cause a significant change in ENSG00000141744 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of PNMT. Does this perturbation cause a significant change in PNMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of ENSG00000070087 is measured. Determine whether ENSG00000070087 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of PFN2 is measured. Determine whether PFN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of ENSG00000105610. Does perturbing KLF1 lead to a significant change in ENSG00000105610 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of KLF1. Does perturbing KLF1 lead to a significant change in KLF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and ENSG00000247516 expression is measured. Determine whether ENSG00000247516 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and MIR4458HG expression is measured. Determine whether MIR4458HG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
77,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of ENSG00000113369 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of ARRDC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2903,You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and ENSG00000064886 expression is observed. Does this perturbation lead to a significant difference in ENSG00000064886 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and CHI3L2 expression is observed. Does this perturbation lead to a significant difference in CHI3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and ENSG00000204482 expression is measured. Determine whether ENSG00000204482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and ENSG00000115738 expression is measured. Determine whether ENSG00000115738 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and ID2 expression is measured. Determine whether ID2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of ENSG00000085185 is measured. Determine whether ENSG00000085185 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of BCORL1 is measured. Determine whether BCORL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in ENSG00000141753 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in IGFBP4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in ENSG00000118058 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in KMT2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and ENSG00000139219 expression is quantified. Does this perturbation result in a significant change in ENSG00000139219 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and COL2A1 expression is quantified. Does this perturbation result in a significant change in COL2A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of ENSG00000163513. Does this perturbation cause a significant change in ENSG00000163513 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of TGFBR2. Does this perturbation cause a significant change in TGFBR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3040,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of ENSG00000189171 is measured. Does this perturbation cause a significant change in ENSG00000189171 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in ENSG00000268621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1538,"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor ENSG00000069535 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000069535 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor MAOB expression. Decide whether this perturbation leads to a significant alteration in MAOB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of ENSG00000101200. Does perturbing TP73 lead to a significant change in ENSG00000101200 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of AVP. Does perturbing TP73 lead to a significant change in AVP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and ENSG00000196188 expression is measured. Determine whether ENSG00000196188 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and CTSE expression is measured. Determine whether CTSE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and ENSG00000164687 expression is quantified. Does this perturbation result in a significant change in ENSG00000164687 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and FABP5 expression is quantified. Does this perturbation result in a significant change in FABP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
633,You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and ENSG00000184697 expression is observed. Does this perturbation lead to a significant difference in ENSG00000184697 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and CLDN6 expression is observed. Does this perturbation lead to a significant difference in CLDN6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of ENSG00000135047 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of CTSL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of ENSG00000204482 is measured. Determine whether ENSG00000204482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2978,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor ENSG00000154127 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000154127 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor UBASH3B expression. Decide whether this perturbation leads to a significant alteration in UBASH3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
293,You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and ENSG00000183770 expression is observed. Does this perturbation lead to a significant difference in ENSG00000183770 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and FOXL2 expression is observed. Does this perturbation lead to a significant difference in FOXL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and ENSG00000101076 expression is measured. Determine whether ENSG00000101076 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and HNF4A expression is measured. Determine whether HNF4A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in ENSG00000160185 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in UBASH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of ENSG00000119535 is measured. Determine whether ENSG00000119535 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of CSF3R is measured. Determine whether CSF3R shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and ENSG00000069482 expression is measured. Determine whether ENSG00000069482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and GAL expression is measured. Determine whether GAL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
860,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2158,"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor ENSG00000119969 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000119969 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor HELLS expression. Decide whether this perturbation leads to a significant alteration in HELLS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of ENSG00000092067. Does this perturbation cause a significant change in ENSG00000092067 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of CEBPE. Does this perturbation cause a significant change in CEBPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1730,"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of ENSG00000163497 is measured. Does this perturbation cause a significant change in ENSG00000163497 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of FEV is measured. Does this perturbation cause a significant change in FEV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
133,You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and ENSG00000030110 expression is observed. Does this perturbation lead to a significant difference in ENSG00000030110 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and BAK1 expression is observed. Does this perturbation lead to a significant difference in BAK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of ENSG00000130829. Does perturbing DUSP9 lead to a significant change in ENSG00000130829 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of DUSP9. Does perturbing DUSP9 lead to a significant change in DUSP9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1168,"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor ENSG00000090238 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000090238 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor YPEL3 expression. Decide whether this perturbation leads to a significant alteration in YPEL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2920,"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of ENSG00000120885 is measured. Does this perturbation cause a significant change in ENSG00000120885 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of CLU is measured. Does this perturbation cause a significant change in CLU expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of ENSG00000206172 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of HBA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2648,"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor ENSG00000196517 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000196517 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor SLC6A9 expression. Decide whether this perturbation leads to a significant alteration in SLC6A9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
190,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of ENSG00000111057 is measured. Does this perturbation cause a significant change in ENSG00000111057 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of KRT18 is measured. Does this perturbation cause a significant change in KRT18 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of ENSG00000154127 is measured. Determine whether ENSG00000154127 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of UBASH3B is measured. Determine whether UBASH3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of ENSG00000092067. Does perturbing CEBPE lead to a significant change in ENSG00000092067 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of CEBPE. Does perturbing CEBPE lead to a significant change in CEBPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of ENSG00000130303. Does this perturbation cause a significant change in ENSG00000130303 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of BST2. Does this perturbation cause a significant change in BST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2850,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of ENSG00000205542 is measured. Does this perturbation cause a significant change in ENSG00000205542 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of TMSB4X is measured. Does this perturbation cause a significant change in TMSB4X expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of ENSG00000158578. Does perturbing PRDM1 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of ALAS2. Does perturbing PRDM1 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2863,You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and ENSG00000075624 expression is observed. Does this perturbation lead to a significant difference in ENSG00000075624 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and ACTB expression is observed. Does this perturbation lead to a significant difference in ACTB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and ENSG00000005187 expression is measured. Determine whether ENSG00000005187 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and ACSM3 expression is measured. Determine whether ACSM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and ENSG00000076356 expression is measured. Determine whether ENSG00000076356 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and PLXNA2 expression is measured. Determine whether PLXNA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
660,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of ENSG00000130176 is measured. Does this perturbation cause a significant change in ENSG00000130176 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of CNN1 is measured. Does this perturbation cause a significant change in CNN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
74,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of ENSG00000113369. Does this perturbation cause a significant change in ENSG00000113369 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of ARRDC3. Does this perturbation cause a significant change in ARRDC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of ENSG00000231312 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of AC007246.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of ENSG00000196517. Does this perturbation cause a significant change in ENSG00000196517 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of SLC6A9. Does this perturbation cause a significant change in SLC6A9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of ENSG00000034152. Does this perturbation cause a significant change in ENSG00000034152 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of MAP2K3. Does this perturbation cause a significant change in MAP2K3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
980,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of ENSG00000163499 is measured. Does this perturbation cause a significant change in ENSG00000163499 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of CRYBA2 is measured. Does this perturbation cause a significant change in CRYBA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2948,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor ENSG00000160185 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000160185 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor UBASH3A expression. Decide whether this perturbation leads to a significant alteration in UBASH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
483,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and ENSG00000153012 expression is observed. Does this perturbation lead to a significant difference in ENSG00000153012 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and LGI2 expression is observed. Does this perturbation lead to a significant difference in LGI2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of ENSG00000273706. Does perturbing LHX1 lead to a significant change in ENSG00000273706 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of LHX1. Does perturbing LHX1 lead to a significant change in LHX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and ENSG00000092067 expression is quantified. Does this perturbation result in a significant change in ENSG00000092067 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and CEBPE expression is quantified. Does this perturbation result in a significant change in CEBPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
9,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and ENSG00000134321 expression is measured. Determine whether ENSG00000134321 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and RSAD2 expression is measured. Determine whether RSAD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of ENSG00000158517 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of NCF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of ENSG00000137841. Does this perturbation cause a significant change in ENSG00000137841 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of PLCB2. Does this perturbation cause a significant change in PLCB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
598,"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor ENSG00000245532 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000245532 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor NEAT1 expression. Decide whether this perturbation leads to a significant alteration in NEAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and ENSG00000141744 expression is measured. Determine whether ENSG00000141744 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and PNMT expression is measured. Determine whether PNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
960,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of ENSG00000163499 is measured. Does this perturbation cause a significant change in ENSG00000163499 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of CRYBA2 is measured. Does this perturbation cause a significant change in CRYBA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and ENSG00000102804 expression is quantified. Does this perturbation result in a significant change in ENSG00000102804 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and TSC22D1 expression is quantified. Does this perturbation result in a significant change in TSC22D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of ENSG00000168140 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of VASN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1290,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of ENSG00000106031 is measured. Does this perturbation cause a significant change in ENSG00000106031 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of HOXA13 is measured. Does this perturbation cause a significant change in HOXA13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of ENSG00000135047. Does this perturbation cause a significant change in ENSG00000135047 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of CTSL. Does this perturbation cause a significant change in CTSL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of ENSG00000140287. Does perturbing POU3F2 lead to a significant change in ENSG00000140287 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of HDC. Does perturbing POU3F2 lead to a significant change in HDC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
14,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of ENSG00000106546. Does this perturbation cause a significant change in ENSG00000106546 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of AHR. Does this perturbation cause a significant change in AHR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
163,You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and ENSG00000250361 expression is observed. Does this perturbation lead to a significant difference in ENSG00000250361 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and GYPB expression is observed. Does this perturbation lead to a significant difference in GYPB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of ENSG00000119969. Does perturbing PLK4 lead to a significant change in ENSG00000119969 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of HELLS. Does perturbing PLK4 lead to a significant change in HELLS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of ENSG00000011600 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of TYROBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2030,"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of ENSG00000114315 is measured. Does this perturbation cause a significant change in ENSG00000114315 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of HES1 is measured. Does this perturbation cause a significant change in HES1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of ENSG00000108984 is measured. Determine whether ENSG00000108984 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of MAP2K6 is measured. Determine whether MAP2K6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in ENSG00000117091 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in CD48 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
10,"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of ENSG00000106546 is measured. Does this perturbation cause a significant change in ENSG00000106546 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of AHR is measured. Does this perturbation cause a significant change in AHR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in ENSG00000075624 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in ACTB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
278,"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and ENSG00000196565 expression is quantified. Does this perturbation result in a significant change in ENSG00000196565 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and HBG2 expression is quantified. Does this perturbation result in a significant change in HBG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1003,You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and ENSG00000204482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000204482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and ENSG00000213934 expression is measured. Determine whether ENSG00000213934 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and HBG1 expression is measured. Determine whether HBG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1420,"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of ENSG00000174498 is measured. Does this perturbation cause a significant change in ENSG00000174498 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of IGDCC3 is measured. Does this perturbation cause a significant change in IGDCC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of ENSG00000247516 is measured. Determine whether ENSG00000247516 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of MIR4458HG is measured. Determine whether MIR4458HG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of ENSG00000149516 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of MS4A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of ENSG00000196565. Does perturbing RHOXF2BB lead to a significant change in ENSG00000196565 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of HBG2. Does perturbing RHOXF2BB lead to a significant change in HBG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
903,You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and ENSG00000005187 expression is observed. Does this perturbation lead to a significant difference in ENSG00000005187 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and ACSM3 expression is observed. Does this perturbation lead to a significant difference in ACSM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2953,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and ENSG00000160185 expression is observed. Does this perturbation lead to a significant difference in ENSG00000160185 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and UBASH3A expression is observed. Does this perturbation lead to a significant difference in UBASH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1860,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of ENSG00000231312 is measured. Does this perturbation cause a significant change in ENSG00000231312 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of AC007246.3 is measured. Does this perturbation cause a significant change in AC007246.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2438,"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor ENSG00000079102 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000079102 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor RUNX1T1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1T1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
35,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in ENSG00000068078 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in FGFR3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and ENSG00000070214 expression is measured. Determine whether ENSG00000070214 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and SLC44A1 expression is measured. Determine whether SLC44A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
84,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of ENSG00000115758. Does this perturbation cause a significant change in ENSG00000115758 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of ODC1. Does this perturbation cause a significant change in ODC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of ENSG00000185198 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and ENSG00000184486 expression is measured. Determine whether ENSG00000184486 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and POU3F2 expression is measured. Determine whether POU3F2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and ENSG00000108821 expression is measured. Determine whether ENSG00000108821 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and COL1A1 expression is measured. Determine whether COL1A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of ENSG00000184009 is measured. Determine whether ENSG00000184009 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of ACTG1 is measured. Determine whether ACTG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of ENSG00000117139 is measured. Determine whether ENSG00000117139 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of KDM5B is measured. Determine whether KDM5B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2560,"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of ENSG00000119535 is measured. Does this perturbation cause a significant change in ENSG00000119535 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of CSF3R is measured. Does this perturbation cause a significant change in CSF3R expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of ENSG00000144655 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of CSRNP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2563,You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and ENSG00000119535 expression is observed. Does this perturbation lead to a significant difference in ENSG00000119535 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and CSF3R expression is observed. Does this perturbation lead to a significant difference in CSF3R expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
108,"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in ENSG00000090382 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in LYZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in ENSG00000183770 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in FOXL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of ENSG00000160185 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of UBASH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of ENSG00000168209 is measured. Determine whether ENSG00000168209 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of DDIT4 is measured. Determine whether DDIT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1823,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and ENSG00000069482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000069482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and GAL expression is observed. Does this perturbation lead to a significant difference in GAL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1833,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and ENSG00000108984 expression is observed. Does this perturbation lead to a significant difference in ENSG00000108984 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and MAP2K6 expression is observed. Does this perturbation lead to a significant difference in MAP2K6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1293,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and ENSG00000106031 expression is observed. Does this perturbation lead to a significant difference in ENSG00000106031 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and HOXA13 expression is observed. Does this perturbation lead to a significant difference in HOXA13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1863,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and ENSG00000231312 expression is observed. Does this perturbation lead to a significant difference in ENSG00000231312 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and AC007246.3 expression is observed. Does this perturbation lead to a significant difference in AC007246.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2000,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of ENSG00000250361 is measured. Does this perturbation cause a significant change in ENSG00000250361 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of GYPB is measured. Does this perturbation cause a significant change in GYPB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and ENSG00000102804 expression is measured. Determine whether ENSG00000102804 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and TSC22D1 expression is measured. Determine whether TSC22D1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of ENSG00000163497. Does this perturbation cause a significant change in ENSG00000163497 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of FEV. Does this perturbation cause a significant change in FEV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of ENSG00000139219. Does this perturbation cause a significant change in ENSG00000139219 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of COL2A1. Does this perturbation cause a significant change in COL2A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
683,You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of ENSG00000204482 is measured. Determine whether ENSG00000204482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of ENSG00000121068. Does perturbing TBX2 lead to a significant change in ENSG00000121068 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of TBX2. Does perturbing TBX2 lead to a significant change in TBX2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2520,"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of ENSG00000234965 is measured. Does this perturbation cause a significant change in ENSG00000234965 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of SHISA8 is measured. Does this perturbation cause a significant change in SHISA8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of ENSG00000141753 is measured. Determine whether ENSG00000141753 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of IGFBP4 is measured. Determine whether IGFBP4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and ENSG00000170180 expression is quantified. Does this perturbation result in a significant change in ENSG00000170180 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and GYPA expression is quantified. Does this perturbation result in a significant change in GYPA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and ENSG00000189171 expression is quantified. Does this perturbation result in a significant change in ENSG00000189171 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and S100A13 expression is quantified. Does this perturbation result in a significant change in S100A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and ENSG00000169410 expression is measured. Determine whether ENSG00000169410 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and PTPN9 expression is measured. Determine whether PTPN9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of ENSG00000205277 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of MUC12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and ENSG00000117091 expression is measured. Determine whether ENSG00000117091 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and CD48 expression is measured. Determine whether CD48 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of ENSG00000196188 is measured. Determine whether ENSG00000196188 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of CTSE is measured. Determine whether CTSE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of ENSG00000158578. Does perturbing C3orf72 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of ALAS2. Does perturbing C3orf72 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and ENSG00000250361 expression is quantified. Does this perturbation result in a significant change in ENSG00000250361 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and GYPB expression is quantified. Does this perturbation result in a significant change in GYPB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of ENSG00000172331. Does this perturbation cause a significant change in ENSG00000172331 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of BPGM. Does this perturbation cause a significant change in BPGM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1733,You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and ENSG00000163497 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163497 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and FEV expression is observed. Does this perturbation lead to a significant difference in FEV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in ENSG00000026297 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in RNASET2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of ENSG00000166450. Does perturbing PRTG lead to a significant change in ENSG00000166450 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of PRTG. Does perturbing PRTG lead to a significant change in PRTG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in ENSG00000172331 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in BPGM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2498,"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1388,"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor ENSG00000188483 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188483 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor IER5L expression. Decide whether this perturbation leads to a significant alteration in IER5L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of ENSG00000070214. Does this perturbation cause a significant change in ENSG00000070214 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of SLC44A1. Does this perturbation cause a significant change in SLC44A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in ENSG00000206172 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in HBA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of ENSG00000124762 is measured. Determine whether ENSG00000124762 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of CDKN1A is measured. Determine whether CDKN1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1930,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of ENSG00000116871 is measured. Does this perturbation cause a significant change in ENSG00000116871 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of MAP7D1 is measured. Does this perturbation cause a significant change in MAP7D1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2108,"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor ENSG00000164920 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000164920 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor OSR2 expression. Decide whether this perturbation leads to a significant alteration in OSR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
373,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and ENSG00000124762 expression is observed. Does this perturbation lead to a significant difference in ENSG00000124762 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ENSG00000099625 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in C19orf26 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1288,"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor ENSG00000198758 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000198758 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor EPS8L3 expression. Decide whether this perturbation leads to a significant alteration in EPS8L3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of ENSG00000160185 is measured. Determine whether ENSG00000160185 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Determine whether UBASH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and ENSG00000011600 expression is measured. Determine whether ENSG00000011600 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and TYROBP expression is measured. Determine whether TYROBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
920,"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of ENSG00000005187 is measured. Does this perturbation cause a significant change in ENSG00000005187 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of ACSM3 is measured. Does this perturbation cause a significant change in ACSM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of ENSG00000183770 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of FOXL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of ENSG00000204482. Does perturbing SPI1 lead to a significant change in ENSG00000204482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of LST1. Does perturbing SPI1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and ENSG00000203989 expression is quantified. Does this perturbation result in a significant change in ENSG00000203989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and RHOXF2BB expression is quantified. Does this perturbation result in a significant change in RHOXF2BB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of ENSG00000034152. Does perturbing MAP2K3 lead to a significant change in ENSG00000034152 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of MAP2K3. Does perturbing MAP2K3 lead to a significant change in MAP2K3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1968,"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor ENSG00000204472 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000204472 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor AIF1 expression. Decide whether this perturbation leads to a significant alteration in AIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of ENSG00000184697 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of CLDN6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2740,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of ENSG00000123473 is measured. Does this perturbation cause a significant change in ENSG00000123473 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of STIL is measured. Does this perturbation cause a significant change in STIL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1553,You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and ENSG00000159388 expression is observed. Does this perturbation lead to a significant difference in ENSG00000159388 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and BTG2 expression is observed. Does this perturbation lead to a significant difference in BTG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in ENSG00000188483 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in IER5L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2748,"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor ENSG00000123473 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000123473 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor STIL expression. Decide whether this perturbation leads to a significant alteration in STIL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of ENSG00000069482. Does this perturbation cause a significant change in ENSG00000069482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of GAL. Does this perturbation cause a significant change in GAL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in ENSG00000130829 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in DUSP9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of ENSG00000268621. Does perturbing SGK1 lead to a significant change in ENSG00000268621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of AC006262.5. Does perturbing SGK1 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in ENSG00000187997 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in C17orf99 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2018,"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor ENSG00000115738 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000115738 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor ID2 expression. Decide whether this perturbation leads to a significant alteration in ID2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and ENSG00000183770 expression is quantified. Does this perturbation result in a significant change in ENSG00000183770 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and FOXL2 expression is quantified. Does this perturbation result in a significant change in FOXL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of ENSG00000170180. Does perturbing CNNM4 lead to a significant change in ENSG00000170180 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of GYPA. Does perturbing CNNM4 lead to a significant change in GYPA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of ENSG00000069482 is measured. Determine whether ENSG00000069482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of GAL is measured. Determine whether GAL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of ENSG00000110492. Does perturbing PRDM1 lead to a significant change in ENSG00000110492 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of MDK. Does perturbing PRDM1 lead to a significant change in MDK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2388,"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor ENSG00000069482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000069482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor GAL expression. Decide whether this perturbation leads to a significant alteration in GAL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
868,"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and ENSG00000120885 expression is quantified. Does this perturbation result in a significant change in ENSG00000120885 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and CLU expression is quantified. Does this perturbation result in a significant change in CLU expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of ENSG00000103241 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of FOXF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of ENSG00000069011 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of PITX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1050,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of ENSG00000090382 is measured. Does this perturbation cause a significant change in ENSG00000090382 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of LYZ is measured. Does this perturbation cause a significant change in LYZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and ENSG00000166450 expression is measured. Determine whether ENSG00000166450 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and PRTG expression is measured. Determine whether PRTG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2178,"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor ENSG00000140287 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000140287 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor HDC expression. Decide whether this perturbation leads to a significant alteration in HDC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of ENSG00000160185 is measured. Determine whether ENSG00000160185 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Determine whether UBASH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and ENSG00000121900 expression is quantified. Does this perturbation result in a significant change in ENSG00000121900 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and TMEM54 expression is quantified. Does this perturbation result in a significant change in TMEM54 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of ENSG00000118777 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of ABCG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
38,"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor ENSG00000068078 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000068078 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor FGFR3 expression. Decide whether this perturbation leads to a significant alteration in FGFR3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in ENSG00000250361 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in GYPB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of ENSG00000204482. Does this perturbation cause a significant change in ENSG00000204482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of ENSG00000116871 is measured. Determine whether ENSG00000116871 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of MAP7D1 is measured. Determine whether MAP7D1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of ENSG00000143401. Does this perturbation cause a significant change in ENSG00000143401 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of ANP32E. Does this perturbation cause a significant change in ANP32E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2458,"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor ENSG00000133317 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000133317 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor LGALS12 expression. Decide whether this perturbation leads to a significant alteration in LGALS12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3110,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of ENSG00000268621 is measured. Does this perturbation cause a significant change in ENSG00000268621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in ENSG00000141744 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in PNMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2873,You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and ENSG00000184009 expression is observed. Does this perturbation lead to a significant difference in ENSG00000184009 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and ACTG1 expression is observed. Does this perturbation lead to a significant difference in ACTG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1783,You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and ENSG00000076356 expression is observed. Does this perturbation lead to a significant difference in ENSG00000076356 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and PLXNA2 expression is observed. Does this perturbation lead to a significant difference in PLXNA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in ENSG00000124762 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of ENSG00000141753. Does perturbing UBASH3A lead to a significant change in ENSG00000141753 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of IGFBP4. Does perturbing UBASH3A lead to a significant change in IGFBP4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
623,You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and ENSG00000115255 expression is observed. Does this perturbation lead to a significant difference in ENSG00000115255 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and REEP6 expression is observed. Does this perturbation lead to a significant difference in REEP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of ENSG00000183770 is measured. Determine whether ENSG00000183770 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of FOXL2 is measured. Determine whether FOXL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and ENSG00000135047 expression is quantified. Does this perturbation result in a significant change in ENSG00000135047 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and CTSL expression is quantified. Does this perturbation result in a significant change in CTSL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and ENSG00000085185 expression is measured. Determine whether ENSG00000085185 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and BCORL1 expression is measured. Determine whether BCORL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
5,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in ENSG00000134321 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in RSAD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
230,"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
658,"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
938,"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor ENSG00000157557 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000157557 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor ETS2 expression. Decide whether this perturbation leads to a significant alteration in ETS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1990,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of ENSG00000185198 is measured. Does this perturbation cause a significant change in ENSG00000185198 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in ENSG00000079102 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in RUNX1T1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of ENSG00000168209 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of DDIT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of ENSG00000258274 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of RP11-887P2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and ENSG00000119535 expression is quantified. Does this perturbation result in a significant change in ENSG00000119535 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and CSF3R expression is quantified. Does this perturbation result in a significant change in CSF3R expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of ENSG00000250361. Does this perturbation cause a significant change in ENSG00000250361 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of GYPB. Does this perturbation cause a significant change in GYPB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1808,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor ENSG00000034152 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000034152 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor MAP2K3 expression. Decide whether this perturbation leads to a significant alteration in MAP2K3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and ENSG00000185198 expression is quantified. Does this perturbation result in a significant change in ENSG00000185198 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of ENSG00000076356. Does this perturbation cause a significant change in ENSG00000076356 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of PLXNA2. Does this perturbation cause a significant change in PLXNA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of ENSG00000163531 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of NFASC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
798,"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and ENSG00000169413 expression is measured. Determine whether ENSG00000169413 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and RNASE6 expression is measured. Determine whether RNASE6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in ENSG00000279529 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in CTD-3222D19.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1210,"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of ENSG00000069011 is measured. Does this perturbation cause a significant change in ENSG00000069011 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of PITX1 is measured. Does this perturbation cause a significant change in PITX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of ENSG00000141744 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of PNMT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
853,You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of ENSG00000101200. Does perturbing TBX3 lead to a significant change in ENSG00000101200 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of AVP. Does perturbing TBX3 lead to a significant change in AVP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of ENSG00000101200 is measured. Determine whether ENSG00000101200 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of AVP is measured. Determine whether AVP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of ENSG00000105223 is measured. Determine whether ENSG00000105223 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of PLD3 is measured. Determine whether PLD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of ENSG00000130656. Does perturbing DUSP9 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of HBZ. Does perturbing DUSP9 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2658,"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of ENSG00000124762. Does this perturbation cause a significant change in ENSG00000124762 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in ENSG00000142945 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in KIF2C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1960,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of ENSG00000204472 is measured. Does this perturbation cause a significant change in ENSG00000204472 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of AIF1 is measured. Does this perturbation cause a significant change in AIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and ENSG00000069482 expression is quantified. Does this perturbation result in a significant change in ENSG00000069482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and GAL expression is quantified. Does this perturbation result in a significant change in GAL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of ENSG00000129757. Does perturbing CDKN1C lead to a significant change in ENSG00000129757 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of CDKN1C. Does perturbing CDKN1C lead to a significant change in CDKN1C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in ENSG00000159388 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in BTG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of ENSG00000189171. Does this perturbation cause a significant change in ENSG00000189171 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of S100A13. Does this perturbation cause a significant change in S100A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of ENSG00000164920. Does perturbing OSR2 lead to a significant change in ENSG00000164920 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of OSR2. Does perturbing OSR2 lead to a significant change in OSR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of ENSG00000117091 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of CD48 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and ENSG00000255346 expression is quantified. Does this perturbation result in a significant change in ENSG00000255346 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and NOX5 expression is quantified. Does this perturbation result in a significant change in NOX5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in ENSG00000189171 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1443,You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and ENSG00000188536 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188536 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and HBA2 expression is observed. Does this perturbation lead to a significant difference in HBA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2398,"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor ENSG00000196565 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000196565 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor HBG2 expression. Decide whether this perturbation leads to a significant alteration in HBG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of ENSG00000185198. Does perturbing MEIS1 lead to a significant change in ENSG00000185198 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of PRSS57. Does perturbing MEIS1 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of ENSG00000243449 is measured. Determine whether ENSG00000243449 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of C4orf48 is measured. Determine whether C4orf48 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and ENSG00000272211 expression is measured. Determine whether ENSG00000272211 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and RP11-347P5.1 expression is measured. Determine whether RP11-347P5.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in ENSG00000117091 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in CD48 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of ENSG00000069482 is measured. Determine whether ENSG00000069482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of GAL is measured. Determine whether GAL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of ENSG00000163513 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of TGFBR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and ENSG00000256713 expression is measured. Determine whether ENSG00000256713 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and PGA5 expression is measured. Determine whether PGA5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2340,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of ENSG00000169410 is measured. Does this perturbation cause a significant change in ENSG00000169410 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of PTPN9 is measured. Does this perturbation cause a significant change in PTPN9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2063,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and ENSG00000197766 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197766 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and CFD expression is observed. Does this perturbation lead to a significant difference in CFD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of ENSG00000186185 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of KIF18B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1068,"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor ENSG00000170608 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000170608 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor FOXA3 expression. Decide whether this perturbation leads to a significant alteration in FOXA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of ENSG00000069482. Does this perturbation cause a significant change in ENSG00000069482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of GAL. Does this perturbation cause a significant change in GAL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and ENSG00000197766 expression is quantified. Does this perturbation result in a significant change in ENSG00000197766 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and CFD expression is quantified. Does this perturbation result in a significant change in CFD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
448,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor ENSG00000129757 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000129757 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor CDKN1C expression. Decide whether this perturbation leads to a significant alteration in CDKN1C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of ENSG00000075624. Does perturbing TMSB4X lead to a significant change in ENSG00000075624 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of ACTB. Does perturbing TMSB4X lead to a significant change in ACTB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2630,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of ENSG00000004939 is measured. Does this perturbation cause a significant change in ENSG00000004939 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of SLC4A1 is measured. Does this perturbation cause a significant change in SLC4A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1668,"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor ENSG00000141744 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000141744 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor PNMT expression. Decide whether this perturbation leads to a significant alteration in PNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in ENSG00000273706 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in LHX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and ENSG00000103241 expression is quantified. Does this perturbation result in a significant change in ENSG00000103241 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and FOXF1 expression is quantified. Does this perturbation result in a significant change in FOXF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and ENSG00000079102 expression is measured. Determine whether ENSG00000079102 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and RUNX1T1 expression is measured. Determine whether RUNX1T1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in ENSG00000188483 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in IER5L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1633,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and ENSG00000142945 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142945 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and KIF2C expression is observed. Does this perturbation lead to a significant difference in KIF2C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of ENSG00000258274 is measured. Determine whether ENSG00000258274 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of RP11-887P2.5 is measured. Determine whether RP11-887P2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in ENSG00000255346 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in NOX5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of ENSG00000184009. Does this perturbation cause a significant change in ENSG00000184009 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of ACTG1. Does this perturbation cause a significant change in ACTG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of ENSG00000079102 is measured. Determine whether ENSG00000079102 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of RUNX1T1 is measured. Determine whether RUNX1T1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2528,"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor ENSG00000234965 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000234965 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor SHISA8 expression. Decide whether this perturbation leads to a significant alteration in SHISA8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of ENSG00000250361. Does this perturbation cause a significant change in ENSG00000250361 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of GYPB. Does this perturbation cause a significant change in GYPB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in ENSG00000092067 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in CEBPE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in ENSG00000204482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and ENSG00000130829 expression is measured. Determine whether ENSG00000130829 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and DUSP9 expression is measured. Determine whether DUSP9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of ENSG00000130656. Does perturbing PTPN12 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of HBZ. Does perturbing PTPN12 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of ENSG00000184697 is measured. Determine whether ENSG00000184697 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of CLDN6 is measured. Determine whether CLDN6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and ENSG00000134321 expression is quantified. Does this perturbation result in a significant change in ENSG00000134321 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and RSAD2 expression is quantified. Does this perturbation result in a significant change in RSAD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1193,You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and ENSG00000109099 expression is observed. Does this perturbation lead to a significant difference in ENSG00000109099 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and PMP22 expression is observed. Does this perturbation lead to a significant difference in PMP22 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in ENSG00000069482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in GAL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
28,"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor ENSG00000077063 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000077063 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor CTTNBP2 expression. Decide whether this perturbation leads to a significant alteration in CTTNBP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1628,"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor ENSG00000142945 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142945 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor KIF2C expression. Decide whether this perturbation leads to a significant alteration in KIF2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of ENSG00000273706. Does this perturbation cause a significant change in ENSG00000273706 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of LHX1. Does this perturbation cause a significant change in LHX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of ENSG00000164920 is measured. Determine whether ENSG00000164920 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of OSR2 is measured. Determine whether OSR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
503,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and ENSG00000070087 expression is observed. Does this perturbation lead to a significant difference in ENSG00000070087 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and PFN2 expression is observed. Does this perturbation lead to a significant difference in PFN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of ENSG00000206172 is measured. Determine whether ENSG00000206172 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of HBA1 is measured. Determine whether HBA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and ENSG00000206172 expression is measured. Determine whether ENSG00000206172 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and HBA1 expression is measured. Determine whether HBA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of ENSG00000163499. Does this perturbation cause a significant change in ENSG00000163499 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of CRYBA2. Does this perturbation cause a significant change in CRYBA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of ENSG00000130176. Does this perturbation cause a significant change in ENSG00000130176 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of CNN1. Does this perturbation cause a significant change in CNN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of ENSG00000268621 is measured. Determine whether ENSG00000268621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and ENSG00000127831 expression is measured. Determine whether ENSG00000127831 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and VIL1 expression is measured. Determine whether VIL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2958,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor ENSG00000160185 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000160185 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor UBASH3A expression. Decide whether this perturbation leads to a significant alteration in UBASH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2823,You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and ENSG00000163513 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163513 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and TGFBR2 expression is observed. Does this perturbation lead to a significant difference in TGFBR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of ENSG00000258274. Does this perturbation cause a significant change in ENSG00000258274 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of RP11-887P2.5. Does this perturbation cause a significant change in RP11-887P2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
550,"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of ENSG00000245848 is measured. Does this perturbation cause a significant change in ENSG00000245848 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of CEBPA is measured. Does this perturbation cause a significant change in CEBPA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and ENSG00000250361 expression is measured. Determine whether ENSG00000250361 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and GYPB expression is measured. Determine whether GYPB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of ENSG00000158578. Does perturbing IER5L lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of ALAS2. Does perturbing IER5L lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and ENSG00000102575 expression is measured. Determine whether ENSG00000102575 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and ACP5 expression is measured. Determine whether ACP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and ENSG00000258274 expression is quantified. Does this perturbation result in a significant change in ENSG00000258274 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and RP11-887P2.5 expression is quantified. Does this perturbation result in a significant change in RP11-887P2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of ENSG00000184486. Does perturbing POU3F2 lead to a significant change in ENSG00000184486 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of POU3F2. Does perturbing POU3F2 lead to a significant change in POU3F2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
888,"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of ENSG00000134294. Does perturbing SLC38A2 lead to a significant change in ENSG00000134294 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of SLC38A2. Does perturbing SLC38A2 lead to a significant change in SLC38A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in ENSG00000204482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
90,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of ENSG00000156030. Does perturbing ELMSAN1 lead to a significant change in ENSG00000156030 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of ELMSAN1. Does perturbing ELMSAN1 lead to a significant change in ELMSAN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of ENSG00000085185. Does perturbing BCORL1 lead to a significant change in ENSG00000085185 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of BCORL1. Does perturbing BCORL1 lead to a significant change in BCORL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in ENSG00000135409 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in AMHR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2183,You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and ENSG00000250361 expression is observed. Does this perturbation lead to a significant difference in ENSG00000250361 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and GYPB expression is observed. Does this perturbation lead to a significant difference in GYPB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2210,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and ENSG00000153012 expression is measured. Determine whether ENSG00000153012 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and LGI2 expression is measured. Determine whether LGI2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2533,You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and ENSG00000170542 expression is observed. Does this perturbation lead to a significant difference in ENSG00000170542 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and SERPINB9 expression is observed. Does this perturbation lead to a significant difference in SERPINB9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1920,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of ENSG00000116871 is measured. Does this perturbation cause a significant change in ENSG00000116871 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of MAP7D1 is measured. Does this perturbation cause a significant change in MAP7D1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
460,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of ENSG00000119535 is measured. Does this perturbation cause a significant change in ENSG00000119535 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of CSF3R is measured. Does this perturbation cause a significant change in CSF3R expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of ENSG00000123473. Does perturbing STIL lead to a significant change in ENSG00000123473 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of STIL. Does perturbing STIL lead to a significant change in STIL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1653,You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and ENSG00000141744 expression is observed. Does this perturbation lead to a significant difference in ENSG00000141744 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and PNMT expression is observed. Does this perturbation lead to a significant difference in PNMT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of ENSG00000164687. Does perturbing KMT2A lead to a significant change in ENSG00000164687 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of FABP5. Does perturbing KMT2A lead to a significant change in FABP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
443,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and ENSG00000129757 expression is observed. Does this perturbation lead to a significant difference in ENSG00000129757 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and CDKN1C expression is observed. Does this perturbation lead to a significant difference in CDKN1C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and ENSG00000185198 expression is quantified. Does this perturbation result in a significant change in ENSG00000185198 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1728,"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor ENSG00000277268 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000277268 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor RP11-445F12.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-445F12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of ENSG00000158578. Does perturbing TGFBR2 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of ALAS2. Does perturbing TGFBR2 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of ENSG00000163497 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of FEV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and ENSG00000179111 expression is measured. Determine whether ENSG00000179111 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and HES7 expression is measured. Determine whether HES7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of ENSG00000206172 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of HBA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of ENSG00000159556 is measured. Determine whether ENSG00000159556 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of ISL2 is measured. Determine whether ISL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
378,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor ENSG00000124762 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000124762 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2358,"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor ENSG00000169410 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169410 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor PTPN9 expression. Decide whether this perturbation leads to a significant alteration in PTPN9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of ENSG00000154127. Does this perturbation cause a significant change in ENSG00000154127 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of UBASH3B. Does this perturbation cause a significant change in UBASH3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1828,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor ENSG00000069482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000069482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor GAL expression. Decide whether this perturbation leads to a significant alteration in GAL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in ENSG00000250361 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in GYPB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of ENSG00000205277 is measured. Determine whether ENSG00000205277 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of MUC12 is measured. Determine whether MUC12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2040,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of ENSG00000115053 is measured. Does this perturbation cause a significant change in ENSG00000115053 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of NCL is measured. Does this perturbation cause a significant change in NCL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1280,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of ENSG00000198758 is measured. Does this perturbation cause a significant change in ENSG00000198758 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of EPS8L3 is measured. Does this perturbation cause a significant change in EPS8L3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of ENSG00000227053 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of RP11-395B7.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of ENSG00000156030. Does this perturbation cause a significant change in ENSG00000156030 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of ELMSAN1. Does this perturbation cause a significant change in ELMSAN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of ENSG00000184486 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of POU3F2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
720,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of ENSG00000108821 is measured. Does this perturbation cause a significant change in ENSG00000108821 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of COL1A1 is measured. Does this perturbation cause a significant change in COL1A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1023,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and ENSG00000129514 expression is observed. Does this perturbation lead to a significant difference in ENSG00000129514 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and FOXA1 expression is observed. Does this perturbation lead to a significant difference in FOXA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of ENSG00000129514. Does this perturbation cause a significant change in ENSG00000129514 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of FOXA1. Does this perturbation cause a significant change in FOXA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
250,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ENSG00000099625 is measured. Does this perturbation cause a significant change in ENSG00000099625 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of C19orf26 is measured. Does this perturbation cause a significant change in C19orf26 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1380,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of ENSG00000188483 is measured. Does this perturbation cause a significant change in ENSG00000188483 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of IER5L is measured. Does this perturbation cause a significant change in IER5L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1040,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of ENSG00000090382 is measured. Does this perturbation cause a significant change in ENSG00000090382 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of LYZ is measured. Does this perturbation cause a significant change in LYZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2258,"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and ENSG00000144655 expression is measured. Determine whether ENSG00000144655 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and CSRNP1 expression is measured. Determine whether CSRNP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of ENSG00000142945 is measured. Determine whether ENSG00000142945 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of KIF2C is measured. Determine whether KIF2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of ENSG00000240065. Does this perturbation cause a significant change in ENSG00000240065 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of PSMB9. Does this perturbation cause a significant change in PSMB9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2828,"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor ENSG00000163513 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163513 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor TGFBR2 expression. Decide whether this perturbation leads to a significant alteration in TGFBR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1660,"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of ENSG00000141744 is measured. Does this perturbation cause a significant change in ENSG00000141744 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of PNMT is measured. Does this perturbation cause a significant change in PNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1180,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of ENSG00000163520 is measured. Does this perturbation cause a significant change in ENSG00000163520 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of FBLN2 is measured. Does this perturbation cause a significant change in FBLN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
21,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of ENSG00000077063. Does perturbing AHR lead to a significant change in ENSG00000077063 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of CTTNBP2. Does perturbing AHR lead to a significant change in CTTNBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and ENSG00000142945 expression is quantified. Does this perturbation result in a significant change in ENSG00000142945 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and KIF2C expression is quantified. Does this perturbation result in a significant change in KIF2C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of ENSG00000250361. Does perturbing ATL1 lead to a significant change in ENSG00000250361 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of GYPB. Does perturbing ATL1 lead to a significant change in GYPB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in ENSG00000108984 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in MAP2K6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2928,"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor ENSG00000120885 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000120885 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor CLU expression. Decide whether this perturbation leads to a significant alteration in CLU expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in ENSG00000169410 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in PTPN9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
678,"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor ENSG00000130176 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130176 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor CNN1 expression. Decide whether this perturbation leads to a significant alteration in CNN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
923,You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and ENSG00000005187 expression is observed. Does this perturbation lead to a significant difference in ENSG00000005187 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and ACSM3 expression is observed. Does this perturbation lead to a significant difference in ACSM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3053,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
753,You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and ENSG00000139219 expression is observed. Does this perturbation lead to a significant difference in ENSG00000139219 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and COL2A1 expression is observed. Does this perturbation lead to a significant difference in COL2A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3133,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and ENSG00000205277 expression is observed. Does this perturbation lead to a significant difference in ENSG00000205277 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and MUC12 expression is observed. Does this perturbation lead to a significant difference in MUC12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and ENSG00000105939 expression is quantified. Does this perturbation result in a significant change in ENSG00000105939 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and ZC3HAV1 expression is quantified. Does this perturbation result in a significant change in ZC3HAV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
143,You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and ENSG00000030110 expression is observed. Does this perturbation lead to a significant difference in ENSG00000030110 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and BAK1 expression is observed. Does this perturbation lead to a significant difference in BAK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in ENSG00000111348 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in ARHGDIB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of ENSG00000135047 is measured. Determine whether ENSG00000135047 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of CTSL is measured. Determine whether CTSL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and ENSG00000157557 expression is measured. Determine whether ENSG00000157557 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and ETS2 expression is measured. Determine whether ETS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and ENSG00000250361 expression is quantified. Does this perturbation result in a significant change in ENSG00000250361 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and GYPB expression is quantified. Does this perturbation result in a significant change in GYPB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
380,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of ENSG00000182871. Does this perturbation cause a significant change in ENSG00000182871 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of COL18A1. Does this perturbation cause a significant change in COL18A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of ENSG00000070214. Does this perturbation cause a significant change in ENSG00000070214 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of SLC44A1. Does this perturbation cause a significant change in SLC44A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of ENSG00000279576 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of AP000769.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of ENSG00000163513. Does perturbing TGFBR2 lead to a significant change in ENSG00000163513 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of TGFBR2. Does perturbing TGFBR2 lead to a significant change in TGFBR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of ENSG00000258274 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of RP11-887P2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and ENSG00000196565 expression is quantified. Does this perturbation result in a significant change in ENSG00000196565 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and HBG2 expression is quantified. Does this perturbation result in a significant change in HBG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and ENSG00000148180 expression is measured. Determine whether ENSG00000148180 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and GSN expression is measured. Determine whether GSN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in ENSG00000076356 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in PLXNA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
268,"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in ENSG00000141744 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in PNMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in ENSG00000162878 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in PKDCC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
123,You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and ENSG00000273706 expression is observed. Does this perturbation lead to a significant difference in ENSG00000273706 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and LHX1 expression is observed. Does this perturbation lead to a significant difference in LHX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2623,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and ENSG00000162493 expression is observed. Does this perturbation lead to a significant difference in ENSG00000162493 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and PDPN expression is observed. Does this perturbation lead to a significant difference in PDPN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
873,You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of ENSG00000139219 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of COL2A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2973,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and ENSG00000154127 expression is observed. Does this perturbation lead to a significant difference in ENSG00000154127 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and UBASH3B expression is observed. Does this perturbation lead to a significant difference in UBASH3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
173,You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and ENSG00000183019 expression is observed. Does this perturbation lead to a significant difference in ENSG00000183019 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and MCEMP1 expression is observed. Does this perturbation lead to a significant difference in MCEMP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2960,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of ENSG00000141753 is measured. Does this perturbation cause a significant change in ENSG00000141753 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of IGFBP4 is measured. Does this perturbation cause a significant change in IGFBP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
498,"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor ENSG00000153012 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000153012 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor LGI2 expression. Decide whether this perturbation leads to a significant alteration in LGI2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and ENSG00000101200 expression is measured. Determine whether ENSG00000101200 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and AVP expression is measured. Determine whether AVP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and ENSG00000026297 expression is quantified. Does this perturbation result in a significant change in ENSG00000026297 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and RNASET2 expression is quantified. Does this perturbation result in a significant change in RNASET2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2988,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor ENSG00000154127 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000154127 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor UBASH3B expression. Decide whether this perturbation leads to a significant alteration in UBASH3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
99,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and ENSG00000273706 expression is measured. Determine whether ENSG00000273706 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and LHX1 expression is measured. Determine whether LHX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of ENSG00000034152 is measured. Determine whether ENSG00000034152 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of MAP2K3 is measured. Determine whether MAP2K3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and ENSG00000148180 expression is quantified. Does this perturbation result in a significant change in ENSG00000148180 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and GSN expression is quantified. Does this perturbation result in a significant change in GSN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in ENSG00000204482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of ENSG00000154127. Does this perturbation cause a significant change in ENSG00000154127 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of UBASH3B. Does this perturbation cause a significant change in UBASH3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of ENSG00000153094. Does perturbing BCL2L11 lead to a significant change in ENSG00000153094 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of BCL2L11. Does perturbing BCL2L11 lead to a significant change in BCL2L11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of ENSG00000102804 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of TSC22D1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
168,"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor ENSG00000250361 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000250361 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor GYPB expression. Decide whether this perturbation leads to a significant alteration in GYPB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of ENSG00000184481 is measured. Determine whether ENSG00000184481 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of FOXO4 is measured. Determine whether FOXO4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of ENSG00000105697 is measured. Determine whether ENSG00000105697 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of HAMP is measured. Determine whether HAMP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
298,"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor ENSG00000183770 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000183770 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor FOXL2 expression. Decide whether this perturbation leads to a significant alteration in FOXL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in ENSG00000135047 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in CTSL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
523,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and ENSG00000092067 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092067 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and CEBPE expression is observed. Does this perturbation lead to a significant difference in CEBPE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and ENSG00000142945 expression is measured. Determine whether ENSG00000142945 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and KIF2C expression is measured. Determine whether KIF2C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in ENSG00000140545 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in MFGE8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1588,"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor ENSG00000177606 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177606 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor JUN expression. Decide whether this perturbation leads to a significant alteration in JUN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in ENSG00000258274 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in RP11-887P2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and ENSG00000174498 expression is measured. Determine whether ENSG00000174498 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and IGDCC3 expression is measured. Determine whether IGDCC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2393,You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and ENSG00000196565 expression is observed. Does this perturbation lead to a significant difference in ENSG00000196565 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and HBG2 expression is observed. Does this perturbation lead to a significant difference in HBG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in ENSG00000185198 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of ENSG00000268621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and ENSG00000240065 expression is measured. Determine whether ENSG00000240065 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and PSMB9 expression is measured. Determine whether PSMB9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of ENSG00000279576. Does this perturbation cause a significant change in ENSG00000279576 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of AP000769.1. Does this perturbation cause a significant change in AP000769.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of ENSG00000120885. Does perturbing TSC22D1 lead to a significant change in ENSG00000120885 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of CLU. Does perturbing TSC22D1 lead to a significant change in CLU expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1533,You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and ENSG00000069535 expression is observed. Does this perturbation lead to a significant difference in ENSG00000069535 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and MAOB expression is observed. Does this perturbation lead to a significant difference in MAOB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and ENSG00000011600 expression is quantified. Does this perturbation result in a significant change in ENSG00000011600 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and TYROBP expression is quantified. Does this perturbation result in a significant change in TYROBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1748,"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor ENSG00000104903 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000104903 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor LYL1 expression. Decide whether this perturbation leads to a significant alteration in LYL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of ENSG00000158373. Does this perturbation cause a significant change in ENSG00000158373 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of HIST1H2BD. Does this perturbation cause a significant change in HIST1H2BD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in ENSG00000188536 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in HBA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of ENSG00000255346 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of NOX5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
743,You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2678,"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor ENSG00000279669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000279669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor RP11-717F1.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-717F1.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of ENSG00000139219 is measured. Determine whether ENSG00000139219 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of COL2A1 is measured. Determine whether COL2A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
458,"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor ENSG00000204482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000204482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of ENSG00000268621. Does perturbing SLC38A2 lead to a significant change in ENSG00000268621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of AC006262.5. Does perturbing SLC38A2 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of ENSG00000139219. Does perturbing COL2A1 lead to a significant change in ENSG00000139219 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of COL2A1. Does perturbing COL2A1 lead to a significant change in COL2A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
208,"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor ENSG00000125144 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000125144 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor MT1G expression. Decide whether this perturbation leads to a significant alteration in MT1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and ENSG00000129757 expression is measured. Determine whether ENSG00000129757 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and CDKN1C expression is measured. Determine whether CDKN1C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of ENSG00000197965. Does perturbing OSR2 lead to a significant change in ENSG00000197965 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of MPZL1. Does perturbing OSR2 lead to a significant change in MPZL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of ENSG00000180785. Does perturbing IRF1 lead to a significant change in ENSG00000180785 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of OR51E1. Does perturbing IRF1 lead to a significant change in OR51E1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and ENSG00000185198 expression is measured. Determine whether ENSG00000185198 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
878,"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in ENSG00000163513 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in TGFBR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2230,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of ENSG00000166450 is measured. Does this perturbation cause a significant change in ENSG00000166450 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of PRTG is measured. Does this perturbation cause a significant change in PRTG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1650,"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of ENSG00000141744 is measured. Does this perturbation cause a significant change in ENSG00000141744 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of PNMT is measured. Does this perturbation cause a significant change in PNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
968,"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor ENSG00000163499 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163499 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor CRYBA2 expression. Decide whether this perturbation leads to a significant alteration in CRYBA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and ENSG00000187997 expression is measured. Determine whether ENSG00000187997 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and C17orf99 expression is measured. Determine whether C17orf99 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and ENSG00000005187 expression is quantified. Does this perturbation result in a significant change in ENSG00000005187 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and ACSM3 expression is quantified. Does this perturbation result in a significant change in ACSM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
390,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of ENSG00000141753 is measured. Does this perturbation cause a significant change in ENSG00000141753 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of IGFBP4 is measured. Does this perturbation cause a significant change in IGFBP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
488,"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor ENSG00000153012 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000153012 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor LGI2 expression. Decide whether this perturbation leads to a significant alteration in LGI2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and ENSG00000183770 expression is measured. Determine whether ENSG00000183770 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and FOXL2 expression is measured. Determine whether FOXL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in ENSG00000179111 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in HES7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2768,"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor ENSG00000121900 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000121900 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor TMEM54 expression. Decide whether this perturbation leads to a significant alteration in TMEM54 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in ENSG00000121900 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in TMEM54 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in ENSG00000102575 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in ACP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1270,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of ENSG00000196188 is measured. Does this perturbation cause a significant change in ENSG00000196188 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of CTSE is measured. Does this perturbation cause a significant change in CTSE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in ENSG00000133317 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in LGALS12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
848,"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor ENSG00000130829 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130829 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor DUSP9 expression. Decide whether this perturbation leads to a significant alteration in DUSP9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of ENSG00000189171 is measured. Determine whether ENSG00000189171 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of S100A13 is measured. Determine whether S100A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
713,You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and ENSG00000170180 expression is observed. Does this perturbation lead to a significant difference in ENSG00000170180 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and GYPA expression is observed. Does this perturbation lead to a significant difference in GYPA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2293,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of ENSG00000119969 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of HELLS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and ENSG00000125144 expression is measured. Determine whether ENSG00000125144 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and MT1G expression is measured. Determine whether MT1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and ENSG00000204482 expression is quantified. Does this perturbation result in a significant change in ENSG00000204482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in ENSG00000130176 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in CNN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of ENSG00000064886 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of CHI3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of ENSG00000070214 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of SLC44A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of ENSG00000204482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1998,"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor ENSG00000185198 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000185198 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of ENSG00000196565 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of HBG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and ENSG00000196517 expression is measured. Determine whether ENSG00000196517 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and SLC6A9 expression is measured. Determine whether SLC6A9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in ENSG00000168140 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in VASN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1393,You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and ENSG00000188483 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188483 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and IER5L expression is observed. Does this perturbation lead to a significant difference in IER5L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
15,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in ENSG00000106546 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in AHR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of ENSG00000105223. Does perturbing HES7 lead to a significant change in ENSG00000105223 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of PLD3. Does perturbing HES7 lead to a significant change in PLD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of ENSG00000135047 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of CTSL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and ENSG00000170542 expression is quantified. Does this perturbation result in a significant change in ENSG00000170542 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and SERPINB9 expression is quantified. Does this perturbation result in a significant change in SERPINB9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of ENSG00000005187. Does this perturbation cause a significant change in ENSG00000005187 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of ACSM3. Does this perturbation cause a significant change in ACSM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of ENSG00000183019 is measured. Determine whether ENSG00000183019 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of MCEMP1 is measured. Determine whether MCEMP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of ENSG00000130656. Does perturbing ATL1 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of HBZ. Does perturbing ATL1 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of ENSG00000140545. Does perturbing CKS1B lead to a significant change in ENSG00000140545 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of MFGE8. Does perturbing CKS1B lead to a significant change in MFGE8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of ENSG00000100097 is measured. Determine whether ENSG00000100097 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of LGALS1 is measured. Determine whether LGALS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1560,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of ENSG00000143674 is measured. Does this perturbation cause a significant change in ENSG00000143674 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of KIAA1804 is measured. Does this perturbation cause a significant change in KIAA1804 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2120,"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of ENSG00000197965 is measured. Does this perturbation cause a significant change in ENSG00000197965 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of MPZL1 is measured. Does this perturbation cause a significant change in MPZL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of ENSG00000159556. Does perturbing ISL2 lead to a significant change in ENSG00000159556 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of ISL2. Does perturbing ISL2 lead to a significant change in ISL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of ENSG00000184481. Does this perturbation cause a significant change in ENSG00000184481 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of FOXO4. Does this perturbation cause a significant change in FOXO4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
75,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in ENSG00000113369 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in ARRDC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of ENSG00000135409. Does this perturbation cause a significant change in ENSG00000135409 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of AMHR2. Does this perturbation cause a significant change in AMHR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2938,"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor ENSG00000102575 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000102575 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor ACP5 expression. Decide whether this perturbation leads to a significant alteration in ACP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of ENSG00000141753. Does perturbing CDKN1B lead to a significant change in ENSG00000141753 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of IGFBP4. Does perturbing CDKN1B lead to a significant change in IGFBP4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and ENSG00000104894 expression is measured. Determine whether ENSG00000104894 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and CD37 expression is measured. Determine whether CD37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
988,"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor ENSG00000163499 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163499 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor CRYBA2 expression. Decide whether this perturbation leads to a significant alteration in CRYBA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1140,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of ENSG00000184481 is measured. Does this perturbation cause a significant change in ENSG00000184481 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of FOXO4 is measured. Does this perturbation cause a significant change in FOXO4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of ENSG00000184697 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of CLDN6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and ENSG00000154127 expression is quantified. Does this perturbation result in a significant change in ENSG00000154127 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and UBASH3B expression is quantified. Does this perturbation result in a significant change in UBASH3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and ENSG00000142945 expression is measured. Determine whether ENSG00000142945 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and KIF2C expression is measured. Determine whether KIF2C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of ENSG00000247516. Does perturbing ZBTB25 lead to a significant change in ENSG00000247516 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of MIR4458HG. Does perturbing ZBTB25 lead to a significant change in MIR4458HG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and ENSG00000100097 expression is measured. Determine whether ENSG00000100097 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and LGALS1 expression is measured. Determine whether LGALS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of ENSG00000119535 is measured. Determine whether ENSG00000119535 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of CSF3R is measured. Determine whether CSF3R shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2688,"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of ENSG00000110492 is measured. Determine whether ENSG00000110492 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of MDK is measured. Determine whether MDK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1540,"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of ENSG00000177606 is measured. Does this perturbation cause a significant change in ENSG00000177606 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of JUN is measured. Does this perturbation cause a significant change in JUN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
323,You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and ENSG00000213934 expression is observed. Does this perturbation lead to a significant difference in ENSG00000213934 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and HBG1 expression is observed. Does this perturbation lead to a significant difference in HBG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1413,You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and ENSG00000174498 expression is observed. Does this perturbation lead to a significant difference in ENSG00000174498 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and IGDCC3 expression is observed. Does this perturbation lead to a significant difference in IGDCC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and ENSG00000183770 expression is quantified. Does this perturbation result in a significant change in ENSG00000183770 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and FOXL2 expression is quantified. Does this perturbation result in a significant change in FOXL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and ENSG00000070214 expression is quantified. Does this perturbation result in a significant change in ENSG00000070214 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and SLC44A1 expression is quantified. Does this perturbation result in a significant change in SLC44A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of ENSG00000169413. Does this perturbation cause a significant change in ENSG00000169413 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of RNASE6. Does this perturbation cause a significant change in RNASE6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of ENSG00000149516 is measured. Determine whether ENSG00000149516 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of MS4A3 is measured. Determine whether MS4A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of ENSG00000157557 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of ETS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2450,"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of ENSG00000133317 is measured. Does this perturbation cause a significant change in ENSG00000133317 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of LGALS12 is measured. Does this perturbation cause a significant change in LGALS12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1950,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2750,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of ENSG00000203989 is measured. Does this perturbation cause a significant change in ENSG00000203989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of RHOXF2BB is measured. Does this perturbation cause a significant change in RHOXF2BB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and ENSG00000163513 expression is measured. Determine whether ENSG00000163513 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and TGFBR2 expression is measured. Determine whether TGFBR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of ENSG00000117091. Does perturbing HOXC13 lead to a significant change in ENSG00000117091 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of CD48. Does perturbing HOXC13 lead to a significant change in CD48 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and ENSG00000108821 expression is quantified. Does this perturbation result in a significant change in ENSG00000108821 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and COL1A1 expression is quantified. Does this perturbation result in a significant change in COL1A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
233,You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of ENSG00000137841 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of PLCB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and ENSG00000185198 expression is quantified. Does this perturbation result in a significant change in ENSG00000185198 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2008,"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor ENSG00000250361 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000250361 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor GYPB expression. Decide whether this perturbation leads to a significant alteration in GYPB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1478,"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor ENSG00000180785 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000180785 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor OR51E1 expression. Decide whether this perturbation leads to a significant alteration in OR51E1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of ENSG00000260793 is measured. Determine whether ENSG00000260793 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of RP5-882C2.2 is measured. Determine whether RP5-882C2.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
248,"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ENSG00000099625 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000099625 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor C19orf26 expression. Decide whether this perturbation leads to a significant alteration in C19orf26 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2963,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and ENSG00000141753 expression is observed. Does this perturbation lead to a significant difference in ENSG00000141753 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and IGFBP4 expression is observed. Does this perturbation lead to a significant difference in IGFBP4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of ENSG00000189171. Does this perturbation cause a significant change in ENSG00000189171 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of S100A13. Does this perturbation cause a significant change in S100A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and ENSG00000026297 expression is measured. Determine whether ENSG00000026297 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and RNASET2 expression is measured. Determine whether RNASET2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of ENSG00000184009 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of ACTG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in ENSG00000141744 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in PNMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of ENSG00000069535. Does this perturbation cause a significant change in ENSG00000069535 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of MAOB. Does this perturbation cause a significant change in MAOB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of ENSG00000204482. Does this perturbation cause a significant change in ENSG00000204482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of ENSG00000143369. Does perturbing PTPN12 lead to a significant change in ENSG00000143369 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of ECM1. Does perturbing PTPN12 lead to a significant change in ECM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1330,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of ENSG00000170689 is measured. Does this perturbation cause a significant change in ENSG00000170689 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of HOXB9 is measured. Does this perturbation cause a significant change in HOXB9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in ENSG00000157557 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in ETS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of ENSG00000177606 is measured. Determine whether ENSG00000177606 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of JUN is measured. Determine whether JUN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and ENSG00000234965 expression is quantified. Does this perturbation result in a significant change in ENSG00000234965 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and SHISA8 expression is quantified. Does this perturbation result in a significant change in SHISA8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2738,"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor ENSG00000143498 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143498 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor TAF1A expression. Decide whether this perturbation leads to a significant alteration in TAF1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of ENSG00000069482 is measured. Determine whether ENSG00000069482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of GAL is measured. Determine whether GAL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of ENSG00000108984 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of MAP2K6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
493,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and ENSG00000153012 expression is observed. Does this perturbation lead to a significant difference in ENSG00000153012 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and LGI2 expression is observed. Does this perturbation lead to a significant difference in LGI2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and ENSG00000185198 expression is measured. Determine whether ENSG00000185198 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of ENSG00000141744. Does perturbing ISL2 lead to a significant change in ENSG00000141744 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of PNMT. Does perturbing ISL2 lead to a significant change in PNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of ENSG00000143674 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of KIAA1804 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
8,"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor ENSG00000134321 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000134321 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor RSAD2 expression. Decide whether this perturbation leads to a significant alteration in RSAD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of ENSG00000102804. Does perturbing TSC22D1 lead to a significant change in ENSG00000102804 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of TSC22D1. Does perturbing TSC22D1 lead to a significant change in TSC22D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in ENSG00000135111 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in TBX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1590,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of ENSG00000143162 is measured. Does this perturbation cause a significant change in ENSG00000143162 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of CREG1 is measured. Does this perturbation cause a significant change in CREG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
480,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of ENSG00000153012 is measured. Does this perturbation cause a significant change in ENSG00000153012 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of LGI2 is measured. Does this perturbation cause a significant change in LGI2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
828,"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor ENSG00000115844 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000115844 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor DLX2 expression. Decide whether this perturbation leads to a significant alteration in DLX2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and ENSG00000198758 expression is quantified. Does this perturbation result in a significant change in ENSG00000198758 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and EPS8L3 expression is quantified. Does this perturbation result in a significant change in EPS8L3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of ENSG00000011600. Does this perturbation cause a significant change in ENSG00000011600 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of TYROBP. Does this perturbation cause a significant change in TYROBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and ENSG00000115053 expression is quantified. Does this perturbation result in a significant change in ENSG00000115053 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and NCL expression is quantified. Does this perturbation result in a significant change in NCL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
990,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of ENSG00000149516 is measured. Does this perturbation cause a significant change in ENSG00000149516 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of MS4A3 is measured. Does this perturbation cause a significant change in MS4A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and ENSG00000140287 expression is measured. Determine whether ENSG00000140287 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and HDC expression is measured. Determine whether HDC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of ENSG00000163531. Does perturbing LYL1 lead to a significant change in ENSG00000163531 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of NFASC. Does perturbing LYL1 lead to a significant change in NFASC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of ENSG00000250361 is measured. Determine whether ENSG00000250361 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of GYPB is measured. Determine whether GYPB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and ENSG00000129757 expression is quantified. Does this perturbation result in a significant change in ENSG00000129757 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and CDKN1C expression is quantified. Does this perturbation result in a significant change in CDKN1C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of ENSG00000104903. Does this perturbation cause a significant change in ENSG00000104903 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of LYL1. Does this perturbation cause a significant change in LYL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and ENSG00000157557 expression is quantified. Does this perturbation result in a significant change in ENSG00000157557 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and ETS2 expression is quantified. Does this perturbation result in a significant change in ETS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1373,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and ENSG00000117091 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117091 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and CD48 expression is observed. Does this perturbation lead to a significant difference in CD48 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in ENSG00000189171 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1810,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of ENSG00000064886 is measured. Does this perturbation cause a significant change in ENSG00000064886 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of CHI3L2 is measured. Does this perturbation cause a significant change in CHI3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of ENSG00000069535 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of MAOB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
790,"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2690,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of ENSG00000189171 is measured. Does this perturbation cause a significant change in ENSG00000189171 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3083,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and ENSG00000247516 expression is observed. Does this perturbation lead to a significant difference in ENSG00000247516 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and MIR4458HG expression is observed. Does this perturbation lead to a significant difference in MIR4458HG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in ENSG00000034152 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in MAP2K3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of ENSG00000169413 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of RNASE6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of ENSG00000185198 is measured. Determine whether ENSG00000185198 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of ENSG00000188483. Does this perturbation cause a significant change in ENSG00000188483 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of IER5L. Does this perturbation cause a significant change in IER5L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
858,"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of ENSG00000234965 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of SHISA8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and ENSG00000169410 expression is measured. Determine whether ENSG00000169410 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and PTPN9 expression is measured. Determine whether PTPN9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3030,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of ENSG00000130303 is measured. Does this perturbation cause a significant change in ENSG00000130303 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of BST2 is measured. Does this perturbation cause a significant change in BST2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
818,"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor ENSG00000115844 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000115844 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor DLX2 expression. Decide whether this perturbation leads to a significant alteration in DLX2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in ENSG00000213934 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in HBG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of ENSG00000106031 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of HOXA13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of ENSG00000115738. Does perturbing MIDN lead to a significant change in ENSG00000115738 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of ID2. Does perturbing MIDN lead to a significant change in ID2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of ENSG00000186051. Does perturbing PTPN13 lead to a significant change in ENSG00000186051 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of TAL2. Does perturbing PTPN13 lead to a significant change in TAL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of ENSG00000174498 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of IGDCC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
32,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and ENSG00000068078 expression is quantified. Does this perturbation result in a significant change in ENSG00000068078 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and FGFR3 expression is quantified. Does this perturbation result in a significant change in FGFR3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and ENSG00000254614 expression is measured. Determine whether ENSG00000254614 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and AP003068.23 expression is measured. Determine whether AP003068.23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of ENSG00000188536. Does this perturbation cause a significant change in ENSG00000188536 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of HBA2. Does this perturbation cause a significant change in HBA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of ENSG00000164920 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of OSR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2518,"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor ENSG00000185198 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000185198 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1010,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and ENSG00000185198 expression is measured. Determine whether ENSG00000185198 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in ENSG00000135047 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in CTSL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
693,You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
16,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of ENSG00000106546 is measured. Determine whether ENSG00000106546 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of AHR is measured. Determine whether AHR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
453,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and ENSG00000204482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000204482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of ENSG00000102575. Does perturbing TSC22D1 lead to a significant change in ENSG00000102575 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of ACP5. Does perturbing TSC22D1 lead to a significant change in ACP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of ENSG00000129757 is measured. Determine whether ENSG00000129757 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of CDKN1C is measured. Determine whether CDKN1C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and ENSG00000163497 expression is quantified. Does this perturbation result in a significant change in ENSG00000163497 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and FEV expression is quantified. Does this perturbation result in a significant change in FEV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2378,"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1160,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of ENSG00000090238 is measured. Does this perturbation cause a significant change in ENSG00000090238 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of YPEL3 is measured. Does this perturbation cause a significant change in YPEL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of ENSG00000250361 is measured. Determine whether ENSG00000250361 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of GYPB is measured. Determine whether GYPB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2493,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2468,"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor ENSG00000206172 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000206172 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor HBA1 expression. Decide whether this perturbation leads to a significant alteration in HBA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
60,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of ENSG00000268621 is measured. Does this perturbation cause a significant change in ENSG00000268621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and ENSG00000162878 expression is quantified. Does this perturbation result in a significant change in ENSG00000162878 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and PKDCC expression is quantified. Does this perturbation result in a significant change in PKDCC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1148,"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor ENSG00000184481 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000184481 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor FOXO4 expression. Decide whether this perturbation leads to a significant alteration in FOXO4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
68,"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor ENSG00000268621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000268621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1708,"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor ENSG00000272211 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000272211 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor RP11-347P5.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-347P5.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of ENSG00000143401. Does perturbing NIT1 lead to a significant change in ENSG00000143401 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of ANP32E. Does perturbing NIT1 lead to a significant change in ANP32E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2933,You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and ENSG00000102575 expression is observed. Does this perturbation lead to a significant difference in ENSG00000102575 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and ACP5 expression is observed. Does this perturbation lead to a significant difference in ACP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of ENSG00000103241 is measured. Determine whether ENSG00000103241 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of FOXF1 is measured. Determine whether FOXF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of ENSG00000166340. Does perturbing FOXO4 lead to a significant change in ENSG00000166340 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of TPP1. Does perturbing FOXO4 lead to a significant change in TPP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2110,"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of ENSG00000164920 is measured. Does this perturbation cause a significant change in ENSG00000164920 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of OSR2 is measured. Does this perturbation cause a significant change in OSR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and ENSG00000163497 expression is measured. Determine whether ENSG00000163497 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and FEV expression is measured. Determine whether FEV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of ENSG00000117139. Does this perturbation cause a significant change in ENSG00000117139 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of KDM5B. Does this perturbation cause a significant change in KDM5B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of ENSG00000177606. Does this perturbation cause a significant change in ENSG00000177606 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of JUN. Does this perturbation cause a significant change in JUN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and ENSG00000154127 expression is measured. Determine whether ENSG00000154127 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and UBASH3B expression is measured. Determine whether UBASH3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of ENSG00000164920. Does this perturbation cause a significant change in ENSG00000164920 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of OSR2. Does this perturbation cause a significant change in OSR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2640,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of ENSG00000196517 is measured. Does this perturbation cause a significant change in ENSG00000196517 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of SLC6A9 is measured. Does this perturbation cause a significant change in SLC6A9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and ENSG00000141744 expression is quantified. Does this perturbation result in a significant change in ENSG00000141744 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and PNMT expression is quantified. Does this perturbation result in a significant change in PNMT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of ENSG00000166501 is measured. Determine whether ENSG00000166501 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of PRKCB is measured. Determine whether PRKCB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3063,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and ENSG00000247516 expression is observed. Does this perturbation lead to a significant difference in ENSG00000247516 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and MIR4458HG expression is observed. Does this perturbation lead to a significant difference in MIR4458HG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and ENSG00000163499 expression is measured. Determine whether ENSG00000163499 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and CRYBA2 expression is measured. Determine whether CRYBA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of ENSG00000115053. Does perturbing NCL lead to a significant change in ENSG00000115053 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of NCL. Does perturbing NCL lead to a significant change in NCL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1213,You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and ENSG00000069011 expression is observed. Does this perturbation lead to a significant difference in ENSG00000069011 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and PITX1 expression is observed. Does this perturbation lead to a significant difference in PITX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2808,"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor ENSG00000101200 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000101200 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor AVP expression. Decide whether this perturbation leads to a significant alteration in AVP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2718,"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor ENSG00000204482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000204482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and ENSG00000163513 expression is quantified. Does this perturbation result in a significant change in ENSG00000163513 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and TGFBR2 expression is quantified. Does this perturbation result in a significant change in TGFBR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in ENSG00000128016 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in ZFP36 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1698,"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor ENSG00000164687 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000164687 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor FABP5 expression. Decide whether this perturbation leads to a significant alteration in FABP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and ENSG00000115844 expression is quantified. Does this perturbation result in a significant change in ENSG00000115844 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and DLX2 expression is quantified. Does this perturbation result in a significant change in DLX2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of ENSG00000188483. Does perturbing IER5L lead to a significant change in ENSG00000188483 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of IER5L. Does perturbing IER5L lead to a significant change in IER5L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of ENSG00000196565 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of HBG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of ENSG00000158578. Does perturbing MAP4K5 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of ALAS2. Does perturbing MAP4K5 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of ENSG00000163497. Does perturbing FEV lead to a significant change in ENSG00000163497 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of FEV. Does perturbing FEV lead to a significant change in FEV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and ENSG00000205542 expression is measured. Determine whether ENSG00000205542 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and TMSB4X expression is measured. Determine whether TMSB4X exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2208,"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor ENSG00000110492 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000110492 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor MDK expression. Decide whether this perturbation leads to a significant alteration in MDK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of ENSG00000110492 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of MDK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of ENSG00000158578. Does perturbing FOXA3 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of ALAS2. Does perturbing FOXA3 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1923,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and ENSG00000116871 expression is observed. Does this perturbation lead to a significant difference in ENSG00000116871 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and MAP7D1 expression is observed. Does this perturbation lead to a significant difference in MAP7D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1423,You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and ENSG00000174498 expression is observed. Does this perturbation lead to a significant difference in ENSG00000174498 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and IGDCC3 expression is observed. Does this perturbation lead to a significant difference in IGDCC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of ENSG00000070214. Does perturbing ZBTB1 lead to a significant change in ENSG00000070214 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of SLC44A1. Does perturbing ZBTB1 lead to a significant change in SLC44A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2913,You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and ENSG00000102804 expression is observed. Does this perturbation lead to a significant difference in ENSG00000102804 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and TSC22D1 expression is observed. Does this perturbation lead to a significant difference in TSC22D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in ENSG00000153012 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in LGI2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2860,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of ENSG00000075624 is measured. Does this perturbation cause a significant change in ENSG00000075624 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of ACTB is measured. Does this perturbation cause a significant change in ACTB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and ENSG00000077063 expression is measured. Determine whether ENSG00000077063 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and CTTNBP2 expression is measured. Determine whether CTTNBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and ENSG00000170689 expression is quantified. Does this perturbation result in a significant change in ENSG00000170689 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and HOXB9 expression is quantified. Does this perturbation result in a significant change in HOXB9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and ENSG00000170689 expression is measured. Determine whether ENSG00000170689 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and HOXB9 expression is measured. Determine whether HOXB9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1700,"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of ENSG00000272211 is measured. Does this perturbation cause a significant change in ENSG00000272211 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of RP11-347P5.1 is measured. Does this perturbation cause a significant change in RP11-347P5.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in ENSG00000129514 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in FOXA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1233,You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and ENSG00000159399 expression is observed. Does this perturbation lead to a significant difference in ENSG00000159399 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and HK2 expression is observed. Does this perturbation lead to a significant difference in HK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of ENSG00000272211 is measured. Determine whether ENSG00000272211 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of RP11-347P5.1 is measured. Determine whether RP11-347P5.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2320,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of ENSG00000182871 is measured. Does this perturbation cause a significant change in ENSG00000182871 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of COL18A1 is measured. Does this perturbation cause a significant change in COL18A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of ENSG00000076356 is measured. Determine whether ENSG00000076356 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of PLXNA2 is measured. Determine whether PLXNA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ENSG00000099625. Does this perturbation cause a significant change in ENSG00000099625 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of C19orf26. Does this perturbation cause a significant change in C19orf26 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of ENSG00000189171. Does perturbing ZBTB10 lead to a significant change in ENSG00000189171 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of S100A13. Does perturbing ZBTB10 lead to a significant change in S100A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of ENSG00000092621. Does perturbing COL1A1 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of PHGDH. Does perturbing COL1A1 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of ENSG00000130829 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of DUSP9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2058,"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor ENSG00000128016 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000128016 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor ZFP36 expression. Decide whether this perturbation leads to a significant alteration in ZFP36 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1670,"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of ENSG00000105610 is measured. Does this perturbation cause a significant change in ENSG00000105610 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of KLF1 is measured. Does this perturbation cause a significant change in KLF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of ENSG00000277268. Does this perturbation cause a significant change in ENSG00000277268 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of RP11-445F12.1. Does this perturbation cause a significant change in RP11-445F12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of ENSG00000064886 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of CHI3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2168,"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor ENSG00000184486 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000184486 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor POU3F2 expression. Decide whether this perturbation leads to a significant alteration in POU3F2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of ENSG00000070214 is measured. Determine whether ENSG00000070214 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of SLC44A1 is measured. Determine whether SLC44A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of ENSG00000183770. Does perturbing FOXL2 lead to a significant change in ENSG00000183770 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of FOXL2. Does perturbing FOXL2 lead to a significant change in FOXL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of ENSG00000273706 is measured. Determine whether ENSG00000273706 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of LHX1 is measured. Determine whether LHX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1070,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and ENSG00000034152 expression is quantified. Does this perturbation result in a significant change in ENSG00000034152 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and MAP2K3 expression is quantified. Does this perturbation result in a significant change in MAP2K3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in ENSG00000170608 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in FOXA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2730,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of ENSG00000143498 is measured. Does this perturbation cause a significant change in ENSG00000143498 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of TAF1A is measured. Does this perturbation cause a significant change in TAF1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in ENSG00000104903 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in LYL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of ENSG00000196188. Does perturbing HNF4A lead to a significant change in ENSG00000196188 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of CTSE. Does perturbing HNF4A lead to a significant change in CTSE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1253,You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and ENSG00000185198 expression is observed. Does this perturbation lead to a significant difference in ENSG00000185198 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and ENSG00000113594 expression is measured. Determine whether ENSG00000113594 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and LIFR expression is measured. Determine whether LIFR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
320,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of ENSG00000213934 is measured. Does this perturbation cause a significant change in ENSG00000213934 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of HBG1 is measured. Does this perturbation cause a significant change in HBG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in ENSG00000196565 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in HBG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and ENSG00000247516 expression is quantified. Does this perturbation result in a significant change in ENSG00000247516 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and MIR4458HG expression is quantified. Does this perturbation result in a significant change in MIR4458HG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in ENSG00000185198 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2448,"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor ENSG00000079102 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000079102 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor RUNX1T1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1T1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in ENSG00000160185 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in UBASH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of ENSG00000163520. Does perturbing GLB1L2 lead to a significant change in ENSG00000163520 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of FBLN2. Does perturbing GLB1L2 lead to a significant change in FBLN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and ENSG00000247516 expression is measured. Determine whether ENSG00000247516 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and MIR4458HG expression is measured. Determine whether MIR4458HG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of ENSG00000118058. Does this perturbation cause a significant change in ENSG00000118058 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of KMT2A. Does this perturbation cause a significant change in KMT2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of ENSG00000139219. Does perturbing COL2A1 lead to a significant change in ENSG00000139219 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of COL2A1. Does perturbing COL2A1 lead to a significant change in COL2A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and ENSG00000204482 expression is measured. Determine whether ENSG00000204482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of ENSG00000135111 is measured. Determine whether ENSG00000135111 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of TBX3 is measured. Determine whether TBX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of ENSG00000170542 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of SERPINB9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of ENSG00000189171. Does perturbing FOXF1 lead to a significant change in ENSG00000189171 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of S100A13. Does perturbing FOXF1 lead to a significant change in S100A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and ENSG00000243449 expression is measured. Determine whether ENSG00000243449 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and C4orf48 expression is measured. Determine whether C4orf48 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2053,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and ENSG00000128016 expression is observed. Does this perturbation lead to a significant difference in ENSG00000128016 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and ZFP36 expression is observed. Does this perturbation lead to a significant difference in ZFP36 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
160,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of ENSG00000250361 is measured. Does this perturbation cause a significant change in ENSG00000250361 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of GYPB is measured. Does this perturbation cause a significant change in GYPB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1548,"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor ENSG00000177606 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177606 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor JUN expression. Decide whether this perturbation leads to a significant alteration in JUN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3130,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of ENSG00000205277 is measured. Does this perturbation cause a significant change in ENSG00000205277 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of MUC12 is measured. Does this perturbation cause a significant change in MUC12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2858,"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor ENSG00000205542 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000205542 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor TMSB4X expression. Decide whether this perturbation leads to a significant alteration in TMSB4X expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1868,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor ENSG00000231312 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000231312 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor AC007246.3 expression. Decide whether this perturbation leads to a significant alteration in AC007246.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of ENSG00000026297 is measured. Determine whether ENSG00000026297 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of RNASET2 is measured. Determine whether RNASET2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and ENSG00000108984 expression is measured. Determine whether ENSG00000108984 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and MAP2K6 expression is measured. Determine whether MAP2K6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and ENSG00000101200 expression is measured. Determine whether ENSG00000101200 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and AVP expression is measured. Determine whether AVP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2180,"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of ENSG00000250361 is measured. Does this perturbation cause a significant change in ENSG00000250361 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of GYPB is measured. Does this perturbation cause a significant change in GYPB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2998,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor ENSG00000185198 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000185198 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and ENSG00000197965 expression is measured. Determine whether ENSG00000197965 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and MPZL1 expression is measured. Determine whether MPZL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of ENSG00000272211. Does perturbing KMT2A lead to a significant change in ENSG00000272211 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of RP11-347P5.1. Does perturbing KMT2A lead to a significant change in RP11-347P5.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2263,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and ENSG00000185198 expression is observed. Does this perturbation lead to a significant difference in ENSG00000185198 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and ENSG00000064886 expression is quantified. Does this perturbation result in a significant change in ENSG00000064886 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and CHI3L2 expression is quantified. Does this perturbation result in a significant change in CHI3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and ENSG00000279576 expression is measured. Determine whether ENSG00000279576 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and AP000769.1 expression is measured. Determine whether AP000769.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
178,"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor ENSG00000183019 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000183019 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor MCEMP1 expression. Decide whether this perturbation leads to a significant alteration in MCEMP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of ENSG00000187997. Does perturbing CDKN1C lead to a significant change in ENSG00000187997 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of C17orf99. Does perturbing CDKN1C lead to a significant change in C17orf99 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and ENSG00000160185 expression is quantified. Does this perturbation result in a significant change in ENSG00000160185 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and UBASH3A expression is quantified. Does this perturbation result in a significant change in UBASH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of ENSG00000130176. Does perturbing CNN1 lead to a significant change in ENSG00000130176 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of CNN1. Does perturbing CNN1 lead to a significant change in CNN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
66,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of ENSG00000268621 is measured. Determine whether ENSG00000268621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1323,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and ENSG00000170689 expression is observed. Does this perturbation lead to a significant difference in ENSG00000170689 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and HOXB9 expression is observed. Does this perturbation lead to a significant difference in HOXB9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of ENSG00000162878 is measured. Determine whether ENSG00000162878 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of PKDCC is measured. Determine whether PKDCC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of ENSG00000196565. Does this perturbation cause a significant change in ENSG00000196565 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of HBG2. Does this perturbation cause a significant change in HBG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1120,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of ENSG00000183770 is measured. Does this perturbation cause a significant change in ENSG00000183770 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of FOXL2 is measured. Does this perturbation cause a significant change in FOXL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3100,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of ENSG00000135047 is measured. Does this perturbation cause a significant change in ENSG00000135047 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of CTSL is measured. Does this perturbation cause a significant change in CTSL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
398,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor ENSG00000141753 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000141753 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor IGFBP4 expression. Decide whether this perturbation leads to a significant alteration in IGFBP4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of ENSG00000102575. Does this perturbation cause a significant change in ENSG00000102575 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of ACP5. Does this perturbation cause a significant change in ACP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of ENSG00000188536 is measured. Determine whether ENSG00000188536 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of HBA2 is measured. Determine whether HBA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1470,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of ENSG00000180785 is measured. Does this perturbation cause a significant change in ENSG00000180785 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of OR51E1 is measured. Does this perturbation cause a significant change in OR51E1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and ENSG00000141744 expression is quantified. Does this perturbation result in a significant change in ENSG00000141744 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and PNMT expression is quantified. Does this perturbation result in a significant change in PNMT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1570,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of ENSG00000005187 is measured. Does this perturbation cause a significant change in ENSG00000005187 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of ACSM3 is measured. Does this perturbation cause a significant change in ACSM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2538,"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor ENSG00000170542 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000170542 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor SERPINB9 expression. Decide whether this perturbation leads to a significant alteration in SERPINB9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in ENSG00000166501 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in PRKCB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2573,You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and ENSG00000268621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000268621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of ENSG00000158578. Does perturbing MAP4K3 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of ALAS2. Does perturbing MAP4K3 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of ENSG00000101200 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of AVP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of ENSG00000250361. Does this perturbation cause a significant change in ENSG00000250361 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of GYPB. Does this perturbation cause a significant change in GYPB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2353,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and ENSG00000169410 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169410 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and PTPN9 expression is observed. Does this perturbation lead to a significant difference in PTPN9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in ENSG00000196517 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in SLC6A9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and ENSG00000005187 expression is measured. Determine whether ENSG00000005187 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and ACSM3 expression is measured. Determine whether ACSM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in ENSG00000102804 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in TSC22D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of ENSG00000069482. Does perturbing FOXL2 lead to a significant change in ENSG00000069482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of GAL. Does perturbing FOXL2 lead to a significant change in GAL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1433,You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in ENSG00000121068 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in TBX2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of ENSG00000069011 is measured. Determine whether ENSG00000069011 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of PITX1 is measured. Determine whether PITX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2613,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and ENSG00000254614 expression is observed. Does this perturbation lead to a significant difference in ENSG00000254614 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and AP003068.23 expression is observed. Does this perturbation lead to a significant difference in AP003068.23 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and ENSG00000113594 expression is quantified. Does this perturbation result in a significant change in ENSG00000113594 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and LIFR expression is quantified. Does this perturbation result in a significant change in LIFR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of ENSG00000204482. Does this perturbation cause a significant change in ENSG00000204482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and ENSG00000149516 expression is measured. Determine whether ENSG00000149516 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and MS4A3 expression is measured. Determine whether MS4A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of ENSG00000245532 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of NEAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in ENSG00000156030 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in ELMSAN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2380,"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of ENSG00000069482 is measured. Does this perturbation cause a significant change in ENSG00000069482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of GAL is measured. Does this perturbation cause a significant change in GAL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of ENSG00000090382 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of LYZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2543,You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and ENSG00000166501 expression is observed. Does this perturbation lead to a significant difference in ENSG00000166501 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and PRKCB expression is observed. Does this perturbation lead to a significant difference in PRKCB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of ENSG00000030110. Does this perturbation cause a significant change in ENSG00000030110 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of BAK1. Does this perturbation cause a significant change in BAK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of ENSG00000272211. Does this perturbation cause a significant change in ENSG00000272211 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of RP11-347P5.1. Does this perturbation cause a significant change in RP11-347P5.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of ENSG00000101076. Does perturbing HNF4A lead to a significant change in ENSG00000101076 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of HNF4A. Does perturbing HNF4A lead to a significant change in HNF4A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and ENSG00000101200 expression is quantified. Does this perturbation result in a significant change in ENSG00000101200 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and AVP expression is quantified. Does this perturbation result in a significant change in AVP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of ENSG00000130656. Does perturbing SLC6A9 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of HBZ. Does perturbing SLC6A9 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1000,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of ENSG00000204482 is measured. Does this perturbation cause a significant change in ENSG00000204482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of ENSG00000137841 is measured. Determine whether ENSG00000137841 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of PLCB2 is measured. Determine whether PLCB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of ENSG00000255346. Does this perturbation cause a significant change in ENSG00000255346 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of NOX5. Does this perturbation cause a significant change in NOX5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of ENSG00000090382. Does perturbing FOXA1 lead to a significant change in ENSG00000090382 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of LYZ. Does perturbing FOXA1 lead to a significant change in LYZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of ENSG00000185198 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of ENSG00000064886. Does perturbing MAP2K3 lead to a significant change in ENSG00000064886 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of CHI3L2. Does perturbing MAP2K3 lead to a significant change in CHI3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and ENSG00000188483 expression is quantified. Does this perturbation result in a significant change in ENSG00000188483 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and IER5L expression is quantified. Does this perturbation result in a significant change in IER5L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and ENSG00000069011 expression is measured. Determine whether ENSG00000069011 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and PITX1 expression is measured. Determine whether PITX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and ENSG00000213934 expression is quantified. Does this perturbation result in a significant change in ENSG00000213934 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and HBG1 expression is quantified. Does this perturbation result in a significant change in HBG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
363,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and ENSG00000124762 expression is observed. Does this perturbation lead to a significant difference in ENSG00000124762 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and ENSG00000166340 expression is measured. Determine whether ENSG00000166340 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and TPP1 expression is measured. Determine whether TPP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of ENSG00000143369. Does this perturbation cause a significant change in ENSG00000143369 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of ECM1. Does this perturbation cause a significant change in ECM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of ENSG00000188536 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of HBA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
478,"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor ENSG00000158517 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158517 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor NCF1 expression. Decide whether this perturbation leads to a significant alteration in NCF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in ENSG00000115844 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in DLX2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in ENSG00000254614 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in AP003068.23 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and ENSG00000101200 expression is quantified. Does this perturbation result in a significant change in ENSG00000101200 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and AVP expression is quantified. Does this perturbation result in a significant change in AVP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and ENSG00000189171 expression is quantified. Does this perturbation result in a significant change in ENSG00000189171 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and S100A13 expression is quantified. Does this perturbation result in a significant change in S100A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of ENSG00000162878 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of PKDCC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of ENSG00000075624 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of ACTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2193,You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2330,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of ENSG00000186051 is measured. Does this perturbation cause a significant change in ENSG00000186051 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of TAL2 is measured. Does this perturbation cause a significant change in TAL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and ENSG00000143369 expression is quantified. Does this perturbation result in a significant change in ENSG00000143369 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and ECM1 expression is quantified. Does this perturbation result in a significant change in ECM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2443,You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and ENSG00000079102 expression is observed. Does this perturbation lead to a significant difference in ENSG00000079102 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and RUNX1T1 expression is observed. Does this perturbation lead to a significant difference in RUNX1T1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of ENSG00000117091. Does this perturbation cause a significant change in ENSG00000117091 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of CD48. Does this perturbation cause a significant change in CD48 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
388,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of ENSG00000163531. Does this perturbation cause a significant change in ENSG00000163531 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of NFASC. Does this perturbation cause a significant change in NFASC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
438,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor ENSG00000187997 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000187997 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor C17orf99 expression. Decide whether this perturbation leads to a significant alteration in C17orf99 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and ENSG00000115844 expression is measured. Determine whether ENSG00000115844 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and DLX2 expression is measured. Determine whether DLX2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and ENSG00000125931 expression is measured. Determine whether ENSG00000125931 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and CITED1 expression is measured. Determine whether CITED1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2980,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of ENSG00000154127 is measured. Does this perturbation cause a significant change in ENSG00000154127 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of UBASH3B is measured. Does this perturbation cause a significant change in UBASH3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of ENSG00000177606. Does this perturbation cause a significant change in ENSG00000177606 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of JUN. Does this perturbation cause a significant change in JUN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2883,You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and ENSG00000101200 expression is observed. Does this perturbation lead to a significant difference in ENSG00000101200 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and AVP expression is observed. Does this perturbation lead to a significant difference in AVP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and ENSG00000124762 expression is quantified. Does this perturbation result in a significant change in ENSG00000124762 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of ENSG00000234965. Does this perturbation cause a significant change in ENSG00000234965 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of SHISA8. Does this perturbation cause a significant change in SHISA8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
608,"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor ENSG00000162878 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000162878 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor PKDCC expression. Decide whether this perturbation leads to a significant alteration in PKDCC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1610,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of ENSG00000077063 is measured. Does this perturbation cause a significant change in ENSG00000077063 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of CTTNBP2 is measured. Does this perturbation cause a significant change in CTTNBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of ENSG00000143674. Does perturbing KIAA1804 lead to a significant change in ENSG00000143674 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of KIAA1804. Does perturbing KIAA1804 lead to a significant change in KIAA1804 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of ENSG00000160185 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of UBASH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
918,"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor ENSG00000156030 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000156030 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor ELMSAN1 expression. Decide whether this perturbation leads to a significant alteration in ELMSAN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2080,"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of ENSG00000143401 is measured. Does this perturbation cause a significant change in ENSG00000143401 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of ANP32E is measured. Does this perturbation cause a significant change in ANP32E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3018,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor ENSG00000070214 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000070214 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor SLC44A1 expression. Decide whether this perturbation leads to a significant alteration in SLC44A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of ENSG00000279529. Does perturbing KIF2C lead to a significant change in ENSG00000279529 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of CTD-3222D19.8. Does perturbing KIF2C lead to a significant change in CTD-3222D19.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of ENSG00000183770 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of FOXL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and ENSG00000180785 expression is measured. Determine whether ENSG00000180785 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and OR51E1 expression is measured. Determine whether OR51E1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of ENSG00000184009. Does perturbing TMSB4X lead to a significant change in ENSG00000184009 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of ACTG1. Does perturbing TMSB4X lead to a significant change in ACTG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
170,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of ENSG00000183019 is measured. Does this perturbation cause a significant change in ENSG00000183019 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of MCEMP1 is measured. Does this perturbation cause a significant change in MCEMP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of ENSG00000205277. Does perturbing ZNF318 lead to a significant change in ENSG00000205277 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of MUC12. Does perturbing ZNF318 lead to a significant change in MUC12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of ENSG00000134294. Does this perturbation cause a significant change in ENSG00000134294 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of SLC38A2. Does this perturbation cause a significant change in SLC38A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of ENSG00000143498 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of TAF1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
933,You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and ENSG00000157557 expression is observed. Does this perturbation lead to a significant difference in ENSG00000157557 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and ETS2 expression is observed. Does this perturbation lead to a significant difference in ETS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2240,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
810,"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of ENSG00000115844 is measured. Does this perturbation cause a significant change in ENSG00000115844 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of DLX2 is measured. Does this perturbation cause a significant change in DLX2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
45,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in ENSG00000185198 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and ENSG00000125144 expression is quantified. Does this perturbation result in a significant change in ENSG00000125144 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and MT1G expression is quantified. Does this perturbation result in a significant change in MT1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
898,"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor ENSG00000069482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000069482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor GAL expression. Decide whether this perturbation leads to a significant alteration in GAL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and ENSG00000185198 expression is quantified. Does this perturbation result in a significant change in ENSG00000185198 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2318,"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor ENSG00000106991 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000106991 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor ENG expression. Decide whether this perturbation leads to a significant alteration in ENG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and ENSG00000141744 expression is quantified. Does this perturbation result in a significant change in ENSG00000141744 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and PNMT expression is quantified. Does this perturbation result in a significant change in PNMT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of ENSG00000111348 is measured. Determine whether ENSG00000111348 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of ARHGDIB is measured. Determine whether ARHGDIB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
763,You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and ENSG00000139219 expression is observed. Does this perturbation lead to a significant difference in ENSG00000139219 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and COL2A1 expression is observed. Does this perturbation lead to a significant difference in COL2A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and ENSG00000135047 expression is quantified. Does this perturbation result in a significant change in ENSG00000135047 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and CTSL expression is quantified. Does this perturbation result in a significant change in CTSL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2160,"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of ENSG00000184486 is measured. Does this perturbation cause a significant change in ENSG00000184486 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of POU3F2 is measured. Does this perturbation cause a significant change in POU3F2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of ENSG00000154127 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of UBASH3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of ENSG00000139219 is measured. Determine whether ENSG00000139219 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of COL2A1 is measured. Determine whether COL2A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1310,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of ENSG00000258274 is measured. Does this perturbation cause a significant change in ENSG00000258274 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of RP11-887P2.5 is measured. Does this perturbation cause a significant change in RP11-887P2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of ENSG00000204482. Does perturbing FOSB lead to a significant change in ENSG00000204482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of LST1. Does perturbing FOSB lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2993,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and ENSG00000185198 expression is observed. Does this perturbation lead to a significant difference in ENSG00000185198 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2943,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and ENSG00000160185 expression is observed. Does this perturbation lead to a significant difference in ENSG00000160185 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and UBASH3A expression is observed. Does this perturbation lead to a significant difference in UBASH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in ENSG00000115738 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in ID2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of ENSG00000128016. Does perturbing NCL lead to a significant change in ENSG00000128016 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of ZFP36. Does perturbing NCL lead to a significant change in ZFP36 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2300,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of ENSG00000143369 is measured. Does this perturbation cause a significant change in ENSG00000143369 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of ECM1 is measured. Does this perturbation cause a significant change in ECM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in ENSG00000157557 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in ETS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1813,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and ENSG00000064886 expression is observed. Does this perturbation lead to a significant difference in ENSG00000064886 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and CHI3L2 expression is observed. Does this perturbation lead to a significant difference in CHI3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
61,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of ENSG00000268621. Does perturbing ARRDC3 lead to a significant change in ENSG00000268621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of AC006262.5. Does perturbing ARRDC3 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of ENSG00000168140. Does perturbing MIDN lead to a significant change in ENSG00000168140 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of VASN. Does perturbing MIDN lead to a significant change in VASN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of ENSG00000170608 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of FOXA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1910,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of ENSG00000169413 is measured. Does this perturbation cause a significant change in ENSG00000169413 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of RNASE6 is measured. Does this perturbation cause a significant change in RNASE6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1238,"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor ENSG00000159399 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000159399 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor HK2 expression. Decide whether this perturbation leads to a significant alteration in HK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2428,"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor ENSG00000064886 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000064886 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor CHI3L2 expression. Decide whether this perturbation leads to a significant alteration in CHI3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
953,You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and ENSG00000157557 expression is observed. Does this perturbation lead to a significant difference in ENSG00000157557 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and ETS2 expression is observed. Does this perturbation lead to a significant difference in ETS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of ENSG00000186051. Does this perturbation cause a significant change in ENSG00000186051 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of TAL2. Does this perturbation cause a significant change in TAL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of ENSG00000134321. Does perturbing AHR lead to a significant change in ENSG00000134321 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of RSAD2. Does perturbing AHR lead to a significant change in RSAD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
238,"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and ENSG00000129514 expression is quantified. Does this perturbation result in a significant change in ENSG00000129514 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and FOXA1 expression is quantified. Does this perturbation result in a significant change in FOXA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
750,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of ENSG00000139219 is measured. Does this perturbation cause a significant change in ENSG00000139219 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of COL2A1 is measured. Does this perturbation cause a significant change in COL2A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of ENSG00000069535. Does perturbing JUN lead to a significant change in ENSG00000069535 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of MAOB. Does perturbing JUN lead to a significant change in MAOB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of ENSG00000149516. Does perturbing FOSB lead to a significant change in ENSG00000149516 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of MS4A3. Does perturbing FOSB lead to a significant change in MS4A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of ENSG00000124762. Does this perturbation cause a significant change in ENSG00000124762 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
34,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of ENSG00000068078. Does this perturbation cause a significant change in ENSG00000068078 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of FGFR3. Does this perturbation cause a significant change in FGFR3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
46,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of ENSG00000185198 is measured. Determine whether ENSG00000185198 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
44,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of ENSG00000185198. Does this perturbation cause a significant change in ENSG00000185198 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of ENSG00000141744. Does perturbing KLF1 lead to a significant change in ENSG00000141744 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of PNMT. Does perturbing KLF1 lead to a significant change in PNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of ENSG00000108821 is measured. Determine whether ENSG00000108821 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of COL1A1 is measured. Determine whether COL1A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of ENSG00000158578. Does perturbing CDKN1C lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of ALAS2. Does perturbing CDKN1C lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of ENSG00000101200. Does this perturbation cause a significant change in ENSG00000101200 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of AVP. Does this perturbation cause a significant change in AVP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in ENSG00000227053 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in RP11-395B7.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of ENSG00000258274. Does this perturbation cause a significant change in ENSG00000258274 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of RP11-887P2.5. Does this perturbation cause a significant change in RP11-887P2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of ENSG00000141744 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of PNMT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1308,"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor ENSG00000117091 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117091 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor CD48 expression. Decide whether this perturbation leads to a significant alteration in CD48 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1368,"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor ENSG00000258274 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000258274 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor RP11-887P2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-887P2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of ENSG00000143162 is measured. Determine whether ENSG00000143162 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of CREG1 is measured. Determine whether CREG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in ENSG00000177606 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in JUN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2413,You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of ENSG00000114315 is measured. Determine whether ENSG00000114315 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of HES1 is measured. Determine whether HES1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in ENSG00000256713 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in PGA5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2003,You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and ENSG00000250361 expression is observed. Does this perturbation lead to a significant difference in ENSG00000250361 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and GYPB expression is observed. Does this perturbation lead to a significant difference in GYPB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1508,"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor ENSG00000159556 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000159556 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor ISL2 expression. Decide whether this perturbation leads to a significant alteration in ISL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and ENSG00000258274 expression is measured. Determine whether ENSG00000258274 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and RP11-887P2.5 expression is measured. Determine whether RP11-887P2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and ENSG00000103241 expression is measured. Determine whether ENSG00000103241 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and FOXF1 expression is measured. Determine whether FOXF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1500,"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of ENSG00000159556 is measured. Does this perturbation cause a significant change in ENSG00000159556 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of ISL2 is measured. Does this perturbation cause a significant change in ISL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of ENSG00000030110 is measured. Determine whether ENSG00000030110 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of BAK1 is measured. Determine whether BAK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of ENSG00000163497 is measured. Determine whether ENSG00000163497 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of FEV is measured. Determine whether FEV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1963,You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and ENSG00000204472 expression is observed. Does this perturbation lead to a significant difference in ENSG00000204472 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and AIF1 expression is observed. Does this perturbation lead to a significant difference in AIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of ENSG00000185198. Does this perturbation cause a significant change in ENSG00000185198 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of ENSG00000266976 is measured. Determine whether ENSG00000266976 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of AC079466.1 is measured. Determine whether AC079466.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
840,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of ENSG00000130829 is measured. Does this perturbation cause a significant change in ENSG00000130829 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of DUSP9 is measured. Does this perturbation cause a significant change in DUSP9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and ENSG00000266976 expression is measured. Determine whether ENSG00000266976 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and AC079466.1 expression is measured. Determine whether AC079466.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2140,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of ENSG00000260793 is measured. Does this perturbation cause a significant change in ENSG00000260793 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of RP5-882C2.2 is measured. Does this perturbation cause a significant change in RP5-882C2.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of ENSG00000206172. Does perturbing PTPN1 lead to a significant change in ENSG00000206172 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of HBA1. Does perturbing PTPN1 lead to a significant change in HBA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of ENSG00000120885. Does this perturbation cause a significant change in ENSG00000120885 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of CLU. Does this perturbation cause a significant change in CLU expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
603,You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and ENSG00000162878 expression is observed. Does this perturbation lead to a significant difference in ENSG00000162878 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and PKDCC expression is observed. Does this perturbation lead to a significant difference in PKDCC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of ENSG00000198758. Does this perturbation cause a significant change in ENSG00000198758 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of EPS8L3. Does this perturbation cause a significant change in EPS8L3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of ENSG00000113594 is measured. Determine whether ENSG00000113594 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of LIFR is measured. Determine whether LIFR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of ENSG00000231312 is measured. Determine whether ENSG00000231312 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of AC007246.3 is measured. Determine whether AC007246.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of ENSG00000154127. Does perturbing UBASH3B lead to a significant change in ENSG00000154127 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of UBASH3B. Does perturbing UBASH3B lead to a significant change in UBASH3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of ENSG00000162493. Does perturbing SLC4A1 lead to a significant change in ENSG00000162493 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of PDPN. Does perturbing SLC4A1 lead to a significant change in PDPN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of ENSG00000092067 is measured. Determine whether ENSG00000092067 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of CEBPE is measured. Determine whether CEBPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and ENSG00000121900 expression is measured. Determine whether ENSG00000121900 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and TMEM54 expression is measured. Determine whether TMEM54 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of ENSG00000203989. Does perturbing STIL lead to a significant change in ENSG00000203989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of RHOXF2BB. Does perturbing STIL lead to a significant change in RHOXF2BB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of ENSG00000185198. Does perturbing PTPN1 lead to a significant change in ENSG00000185198 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of PRSS57. Does perturbing PTPN1 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2600,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of ENSG00000135047 is measured. Does this perturbation cause a significant change in ENSG00000135047 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of CTSL is measured. Does this perturbation cause a significant change in CTSL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2523,You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and ENSG00000234965 expression is observed. Does this perturbation lead to a significant difference in ENSG00000234965 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and SHISA8 expression is observed. Does this perturbation lead to a significant difference in SHISA8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2813,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and ENSG00000135111 expression is observed. Does this perturbation lead to a significant difference in ENSG00000135111 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and TBX3 expression is observed. Does this perturbation lead to a significant difference in TBX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of ENSG00000245532. Does perturbing CITED1 lead to a significant change in ENSG00000245532 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of NEAT1. Does perturbing CITED1 lead to a significant change in NEAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and ENSG00000198758 expression is measured. Determine whether ENSG00000198758 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and EPS8L3 expression is measured. Determine whether EPS8L3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
263,You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and ENSG00000100097 expression is quantified. Does this perturbation result in a significant change in ENSG00000100097 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and LGALS1 expression is quantified. Does this perturbation result in a significant change in LGALS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in ENSG00000143674 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in KIAA1804 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of ENSG00000170689 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of HOXB9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of ENSG00000117091. Does perturbing HOXA13 lead to a significant change in ENSG00000117091 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of CD48. Does perturbing HOXA13 lead to a significant change in CD48 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of ENSG00000254614. Does this perturbation cause a significant change in ENSG00000254614 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of AP003068.23. Does this perturbation cause a significant change in AP003068.23 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
52,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and ENSG00000160838 expression is quantified. Does this perturbation result in a significant change in ENSG00000160838 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and LRRC71 expression is quantified. Does this perturbation result in a significant change in LRRC71 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1983,You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and ENSG00000185198 expression is observed. Does this perturbation lead to a significant difference in ENSG00000185198 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and ENSG00000160185 expression is quantified. Does this perturbation result in a significant change in ENSG00000160185 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and UBASH3A expression is quantified. Does this perturbation result in a significant change in UBASH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in ENSG00000069482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in GAL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and ENSG00000106991 expression is measured. Determine whether ENSG00000106991 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and ENG expression is measured. Determine whether ENG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of ENSG00000189171 is measured. Determine whether ENSG00000189171 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of S100A13 is measured. Determine whether S100A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of ENSG00000111348. Does this perturbation cause a significant change in ENSG00000111348 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of ARHGDIB. Does this perturbation cause a significant change in ARHGDIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of ENSG00000185198 is measured. Determine whether ENSG00000185198 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1970,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of ENSG00000111348 is measured. Does this perturbation cause a significant change in ENSG00000111348 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of ARHGDIB is measured. Does this perturbation cause a significant change in ARHGDIB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2558,"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor ENSG00000118515 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000118515 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor SGK1 expression. Decide whether this perturbation leads to a significant alteration in SGK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in ENSG00000143369 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in ECM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of ENSG00000111057 is measured. Determine whether ENSG00000111057 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of KRT18 is measured. Determine whether KRT18 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in ENSG00000069535 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in MAOB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
463,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and ENSG00000119535 expression is observed. Does this perturbation lead to a significant difference in ENSG00000119535 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and CSF3R expression is observed. Does this perturbation lead to a significant difference in CSF3R expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of ENSG00000125931 is measured. Determine whether ENSG00000125931 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of CITED1 is measured. Determine whether CITED1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
19,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and ENSG00000106546 expression is measured. Determine whether ENSG00000106546 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and AHR expression is measured. Determine whether AHR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and ENSG00000117091 expression is quantified. Does this perturbation result in a significant change in ENSG00000117091 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and CD48 expression is quantified. Does this perturbation result in a significant change in CD48 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of ENSG00000148180 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of GSN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and ENSG00000184009 expression is measured. Determine whether ENSG00000184009 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and ACTG1 expression is measured. Determine whether ACTG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in ENSG00000180785 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in OR51E1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of ENSG00000130303 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of BST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of ENSG00000129757. Does perturbing CDKN1B lead to a significant change in ENSG00000129757 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of CDKN1C. Does perturbing CDKN1B lead to a significant change in CDKN1C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of ENSG00000106991 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of ENG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and ENSG00000105697 expression is quantified. Does this perturbation result in a significant change in ENSG00000105697 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and HAMP expression is quantified. Does this perturbation result in a significant change in HAMP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
548,"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor ENSG00000243449 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000243449 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor C4orf48 expression. Decide whether this perturbation leads to a significant alteration in C4orf48 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
43,You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and ENSG00000185198 expression is observed. Does this perturbation lead to a significant difference in ENSG00000185198 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in ENSG00000070087 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in PFN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of ENSG00000101200. Does perturbing TBX3 lead to a significant change in ENSG00000101200 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of AVP. Does perturbing TBX3 lead to a significant change in AVP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in ENSG00000139219 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in COL2A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of ENSG00000158869. Does perturbing ZBTB10 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of FCER1G. Does perturbing ZBTB10 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of ENSG00000069482. Does perturbing RHOXF2BB lead to a significant change in ENSG00000069482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of GAL. Does perturbing RHOXF2BB lead to a significant change in GAL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of ENSG00000153012. Does perturbing CEBPB lead to a significant change in ENSG00000153012 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of LGI2. Does perturbing CEBPB lead to a significant change in LGI2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of ENSG00000125144. Does this perturbation cause a significant change in ENSG00000125144 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of MT1G. Does this perturbation cause a significant change in MT1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of ENSG00000255346. Does perturbing TP73 lead to a significant change in ENSG00000255346 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of NOX5. Does perturbing TP73 lead to a significant change in NOX5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in ENSG00000196188 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in CTSE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in ENSG00000164920 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in OSR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and ENSG00000071967 expression is measured. Determine whether ENSG00000071967 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and CYBRD1 expression is measured. Determine whether CYBRD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2128,"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor ENSG00000197965 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197965 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor MPZL1 expression. Decide whether this perturbation leads to a significant alteration in MPZL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
283,You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and ENSG00000102804 expression is observed. Does this perturbation lead to a significant difference in ENSG00000102804 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and TSC22D1 expression is observed. Does this perturbation lead to a significant difference in TSC22D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of ENSG00000104894. Does this perturbation cause a significant change in ENSG00000104894 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of CD37. Does this perturbation cause a significant change in CD37 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1580,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of ENSG00000177606 is measured. Does this perturbation cause a significant change in ENSG00000177606 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of JUN is measured. Does this perturbation cause a significant change in JUN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2548,"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor ENSG00000166501 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000166501 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor PRKCB expression. Decide whether this perturbation leads to a significant alteration in PRKCB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of ENSG00000231312. Does this perturbation cause a significant change in ENSG00000231312 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of AC007246.3. Does this perturbation cause a significant change in AC007246.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of ENSG00000030110 is measured. Determine whether ENSG00000030110 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of BAK1 is measured. Determine whether BAK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of ENSG00000124762 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and ENSG00000204482 expression is quantified. Does this perturbation result in a significant change in ENSG00000204482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
73,You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and ENSG00000113369 expression is observed. Does this perturbation lead to a significant difference in ENSG00000113369 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and ARRDC3 expression is observed. Does this perturbation lead to a significant difference in ARRDC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of ENSG00000197766 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of CFD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of ENSG00000113594 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of LIFR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ENSG00000099625. Does perturbing C19orf26 lead to a significant change in ENSG00000099625 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of C19orf26. Does perturbing C19orf26 lead to a significant change in C19orf26 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of ENSG00000143498 is measured. Determine whether ENSG00000143498 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of TAF1A is measured. Determine whether TAF1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of ENSG00000188483 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of IER5L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and ENSG00000168209 expression is quantified. Does this perturbation result in a significant change in ENSG00000168209 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and DDIT4 expression is quantified. Does this perturbation result in a significant change in DDIT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1623,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and ENSG00000142945 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142945 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and KIF2C expression is observed. Does this perturbation lead to a significant difference in KIF2C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and ENSG00000110492 expression is measured. Determine whether ENSG00000110492 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and MDK expression is measured. Determine whether MDK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of ENSG00000243449. Does perturbing CELF2 lead to a significant change in ENSG00000243449 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of C4orf48. Does perturbing CELF2 lead to a significant change in C4orf48 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in ENSG00000170542 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in SERPINB9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of ENSG00000118515 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of SGK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of ENSG00000069482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of GAL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
400,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in ENSG00000070214 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in SLC44A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of ENSG00000141744 is measured. Determine whether ENSG00000141744 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of PNMT is measured. Determine whether PNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of ENSG00000279669 is measured. Determine whether ENSG00000279669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of RP11-717F1.1 is measured. Determine whether RP11-717F1.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1250,"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of ENSG00000185198 is measured. Does this perturbation cause a significant change in ENSG00000185198 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of ENSG00000197965 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of MPZL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of ENSG00000101076. Does this perturbation cause a significant change in ENSG00000101076 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of HNF4A. Does this perturbation cause a significant change in HNF4A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1230,"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of ENSG00000159399 is measured. Does this perturbation cause a significant change in ENSG00000159399 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of HK2 is measured. Does this perturbation cause a significant change in HK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and ENSG00000184697 expression is quantified. Does this perturbation result in a significant change in ENSG00000184697 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and CLDN6 expression is quantified. Does this perturbation result in a significant change in CLDN6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1528,"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor ENSG00000141744 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000141744 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor PNMT expression. Decide whether this perturbation leads to a significant alteration in PNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1903,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ENSG00000099625. Does this perturbation cause a significant change in ENSG00000099625 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of C19orf26. Does this perturbation cause a significant change in C19orf26 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2480,"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of ENSG00000105697 is measured. Does this perturbation cause a significant change in ENSG00000105697 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of HAMP is measured. Does this perturbation cause a significant change in HAMP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of ENSG00000266976. Does perturbing MAP2K6 lead to a significant change in ENSG00000266976 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of AC079466.1. Does perturbing MAP2K6 lead to a significant change in AC079466.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and ENSG00000135047 expression is measured. Determine whether ENSG00000135047 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and CTSL expression is measured. Determine whether CTSL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of ENSG00000169410. Does this perturbation cause a significant change in ENSG00000169410 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of PTPN9. Does this perturbation cause a significant change in PTPN9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of ENSG00000156030 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of ELMSAN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3068,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor ENSG00000247516 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000247516 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor MIR4458HG expression. Decide whether this perturbation leads to a significant alteration in MIR4458HG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2163,You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and ENSG00000184486 expression is observed. Does this perturbation lead to a significant difference in ENSG00000184486 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and POU3F2 expression is observed. Does this perturbation lead to a significant difference in POU3F2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of ENSG00000101200. Does this perturbation cause a significant change in ENSG00000101200 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of AVP. Does this perturbation cause a significant change in AVP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of ENSG00000186051 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of TAL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and ENSG00000124762 expression is measured. Determine whether ENSG00000124762 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1048,"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor ENSG00000090382 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000090382 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor LYZ expression. Decide whether this perturbation leads to a significant alteration in LYZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and ENSG00000105697 expression is measured. Determine whether ENSG00000105697 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and HAMP expression is measured. Determine whether HAMP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of ENSG00000118777 is measured. Determine whether ENSG00000118777 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of ABCG2 is measured. Determine whether ABCG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of ENSG00000143162. Does perturbing KIF18B lead to a significant change in ENSG00000143162 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of CREG1. Does perturbing KIF18B lead to a significant change in CREG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
650,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3070,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2113,You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and ENSG00000164920 expression is observed. Does this perturbation lead to a significant difference in ENSG00000164920 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and OSR2 expression is observed. Does this perturbation lead to a significant difference in OSR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
950,"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of ENSG00000157557 is measured. Does this perturbation cause a significant change in ENSG00000157557 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of ETS2 is measured. Does this perturbation cause a significant change in ETS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3080,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of ENSG00000247516 is measured. Does this perturbation cause a significant change in ENSG00000247516 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of MIR4458HG is measured. Does this perturbation cause a significant change in MIR4458HG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2510,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of ENSG00000185198 is measured. Does this perturbation cause a significant change in ENSG00000185198 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of ENSG00000153012. Does this perturbation cause a significant change in ENSG00000153012 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of LGI2. Does this perturbation cause a significant change in LGI2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of ENSG00000071967 is measured. Determine whether ENSG00000071967 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of CYBRD1 is measured. Determine whether CYBRD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
58,"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor ENSG00000160838 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000160838 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor LRRC71 expression. Decide whether this perturbation leads to a significant alteration in LRRC71 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1038,"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor ENSG00000129514 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000129514 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor FOXA1 expression. Decide whether this perturbation leads to a significant alteration in FOXA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
4,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of ENSG00000134321. Does this perturbation cause a significant change in ENSG00000134321 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of RSAD2. Does this perturbation cause a significant change in RSAD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in ENSG00000064886 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in CHI3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of ENSG00000159399 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of HK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
12,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and ENSG00000106546 expression is quantified. Does this perturbation result in a significant change in ENSG00000106546 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and AHR expression is quantified. Does this perturbation result in a significant change in AHR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
243,You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ENSG00000099625 expression is observed. Does this perturbation lead to a significant difference in ENSG00000099625 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and C19orf26 expression is observed. Does this perturbation lead to a significant difference in C19orf26 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
33,You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and ENSG00000068078 expression is observed. Does this perturbation lead to a significant difference in ENSG00000068078 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and FGFR3 expression is observed. Does this perturbation lead to a significant difference in FGFR3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
718,"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor ENSG00000170180 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000170180 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor GYPA expression. Decide whether this perturbation leads to a significant alteration in GYPA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of ENSG00000213934. Does perturbing CBFA2T3 lead to a significant change in ENSG00000213934 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of HBG1. Does perturbing CBFA2T3 lead to a significant change in HBG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of ENSG00000204472. Does this perturbation cause a significant change in ENSG00000204472 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of AIF1. Does this perturbation cause a significant change in AIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in ENSG00000184697 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in CLDN6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
808,"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor ENSG00000100097 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000100097 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor LGALS1 expression. Decide whether this perturbation leads to a significant alteration in LGALS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1093,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and ENSG00000103241 expression is observed. Does this perturbation lead to a significant difference in ENSG00000103241 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and FOXF1 expression is observed. Does this perturbation lead to a significant difference in FOXF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
113,You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and ENSG00000250361 expression is observed. Does this perturbation lead to a significant difference in ENSG00000250361 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and GYPB expression is observed. Does this perturbation lead to a significant difference in GYPB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of ENSG00000076356 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of PLXNA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of ENSG00000189171 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of S100A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of ENSG00000140545 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of MFGE8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of ENSG00000092067 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of CEBPE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of ENSG00000114315 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of HES1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
600,"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of ENSG00000162878 is measured. Does this perturbation cause a significant change in ENSG00000162878 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of PKDCC is measured. Does this perturbation cause a significant change in PKDCC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2503,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of ENSG00000130176 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of CNN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and ENSG00000162493 expression is quantified. Does this perturbation result in a significant change in ENSG00000162493 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and PDPN expression is quantified. Does this perturbation result in a significant change in PDPN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of ENSG00000185198. Does perturbing MEIS1 lead to a significant change in ENSG00000185198 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of PRSS57. Does perturbing MEIS1 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and ENSG00000166501 expression is quantified. Does this perturbation result in a significant change in ENSG00000166501 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and PRKCB expression is quantified. Does this perturbation result in a significant change in PRKCB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and ENSG00000117091 expression is quantified. Does this perturbation result in a significant change in ENSG00000117091 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and CD48 expression is quantified. Does this perturbation result in a significant change in CD48 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of ENSG00000104903. Does perturbing LYL1 lead to a significant change in ENSG00000104903 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of LYL1. Does perturbing LYL1 lead to a significant change in LYL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of ENSG00000183770. Does this perturbation cause a significant change in ENSG00000183770 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of FOXL2. Does this perturbation cause a significant change in FOXL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of ENSG00000185198 is measured. Determine whether ENSG00000185198 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2878,"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor ENSG00000184009 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000184009 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor ACTG1 expression. Decide whether this perturbation leads to a significant alteration in ACTG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of ENSG00000258274. Does perturbing HOXA13 lead to a significant change in ENSG00000258274 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of RP11-887P2.5. Does perturbing HOXA13 lead to a significant change in RP11-887P2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and ENSG00000185198 expression is quantified. Does this perturbation result in a significant change in ENSG00000185198 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of ENSG00000159399. Does this perturbation cause a significant change in ENSG00000159399 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of HK2. Does this perturbation cause a significant change in HK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of ENSG00000143162. Does this perturbation cause a significant change in ENSG00000143162 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of CREG1. Does this perturbation cause a significant change in CREG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
500,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of ENSG00000070087 is measured. Does this perturbation cause a significant change in ENSG00000070087 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of PFN2 is measured. Does this perturbation cause a significant change in PFN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of ENSG00000121900 is measured. Determine whether ENSG00000121900 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of TMEM54 is measured. Determine whether TMEM54 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in ENSG00000064886 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in CHI3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of ENSG00000141744. Does this perturbation cause a significant change in ENSG00000141744 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of PNMT. Does this perturbation cause a significant change in PNMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of ENSG00000143674 is measured. Determine whether ENSG00000143674 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of KIAA1804 is measured. Determine whether KIAA1804 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2098,"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor ENSG00000158373 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158373 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor HIST1H2BD expression. Decide whether this perturbation leads to a significant alteration in HIST1H2BD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of ENSG00000273706. Does perturbing BAK1 lead to a significant change in ENSG00000273706 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of LHX1. Does perturbing BAK1 lead to a significant change in LHX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of ENSG00000005187. Does this perturbation cause a significant change in ENSG00000005187 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of ACSM3. Does this perturbation cause a significant change in ACSM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3108,"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor ENSG00000135047 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000135047 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor CTSL expression. Decide whether this perturbation leads to a significant alteration in CTSL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of ENSG00000265972. Does perturbing HK2 lead to a significant change in ENSG00000265972 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of TXNIP. Does perturbing HK2 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and ENSG00000130176 expression is quantified. Does this perturbation result in a significant change in ENSG00000130176 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and CNN1 expression is quantified. Does this perturbation result in a significant change in CNN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and ENSG00000156030 expression is quantified. Does this perturbation result in a significant change in ENSG00000156030 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and ELMSAN1 expression is quantified. Does this perturbation result in a significant change in ELMSAN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and ENSG00000117139 expression is quantified. Does this perturbation result in a significant change in ENSG00000117139 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and KDM5B expression is quantified. Does this perturbation result in a significant change in KDM5B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of ENSG00000163531 is measured. Determine whether ENSG00000163531 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of NFASC is measured. Determine whether NFASC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and ENSG00000090238 expression is measured. Determine whether ENSG00000090238 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and YPEL3 expression is measured. Determine whether YPEL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
36,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of ENSG00000068078 is measured. Determine whether ENSG00000068078 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of FGFR3 is measured. Determine whether FGFR3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2900,"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of ENSG00000064886 is measured. Does this perturbation cause a significant change in ENSG00000064886 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of CHI3L2 is measured. Does this perturbation cause a significant change in CHI3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1318,"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor ENSG00000258274 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000258274 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor RP11-887P2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-887P2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of ENSG00000203989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of RHOXF2BB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of ENSG00000160185. Does perturbing UBASH3A lead to a significant change in ENSG00000160185 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of UBASH3A. Does perturbing UBASH3A lead to a significant change in UBASH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of ENSG00000130656. Does perturbing CNNM4 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of HBZ. Does perturbing CNNM4 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of ENSG00000135047. Does perturbing SLC38A2 lead to a significant change in ENSG00000135047 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of CTSL. Does perturbing SLC38A2 lead to a significant change in CTSL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of ENSG00000130303. Does perturbing ZBTB10 lead to a significant change in ENSG00000130303 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of BST2. Does perturbing ZBTB10 lead to a significant change in BST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of ENSG00000196517 is measured. Determine whether ENSG00000196517 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of SLC6A9 is measured. Determine whether SLC6A9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
690,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and ENSG00000184486 expression is quantified. Does this perturbation result in a significant change in ENSG00000184486 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and POU3F2 expression is quantified. Does this perturbation result in a significant change in POU3F2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in ENSG00000118777 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in ABCG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2233,You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and ENSG00000166450 expression is observed. Does this perturbation lead to a significant difference in ENSG00000166450 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and PRTG expression is observed. Does this perturbation lead to a significant difference in PRTG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of ENSG00000079102 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of RUNX1T1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2930,"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of ENSG00000102575 is measured. Does this perturbation cause a significant change in ENSG00000102575 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of ACP5 is measured. Does this perturbation cause a significant change in ACP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and ENSG00000206172 expression is measured. Determine whether ENSG00000206172 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and HBA1 expression is measured. Determine whether HBA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of ENSG00000158517. Does perturbing CEBPA lead to a significant change in ENSG00000158517 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of NCF1. Does perturbing CEBPA lead to a significant change in NCF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of ENSG00000197766 is measured. Determine whether ENSG00000197766 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of CFD is measured. Determine whether CFD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2628,"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor ENSG00000162493 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000162493 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor PDPN expression. Decide whether this perturbation leads to a significant alteration in PDPN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1608,"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor ENSG00000186185 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000186185 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor KIF18B expression. Decide whether this perturbation leads to a significant alteration in KIF18B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
908,"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor ENSG00000005187 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000005187 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor ACSM3 expression. Decide whether this perturbation leads to a significant alteration in ACSM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of ENSG00000148180. Does perturbing HOXB9 lead to a significant change in ENSG00000148180 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of GSN. Does perturbing HOXB9 lead to a significant change in GSN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of ENSG00000234965 is measured. Determine whether ENSG00000234965 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of SHISA8 is measured. Determine whether SHISA8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in ENSG00000204482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of ENSG00000158373 is measured. Determine whether ENSG00000158373 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of HIST1H2BD is measured. Determine whether HIST1H2BD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and ENSG00000153094 expression is measured. Determine whether ENSG00000153094 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and BCL2L11 expression is measured. Determine whether BCL2L11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of ENSG00000142945 is measured. Determine whether ENSG00000142945 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of KIF2C is measured. Determine whether KIF2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of ENSG00000164687 is measured. Determine whether ENSG00000164687 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of FABP5 is measured. Determine whether FABP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1918,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor ENSG00000169413 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169413 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor RNASE6 expression. Decide whether this perturbation leads to a significant alteration in RNASE6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in ENSG00000153012 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in LGI2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and ENSG00000268621 expression is measured. Determine whether ENSG00000268621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
303,You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and ENSG00000196565 expression is observed. Does this perturbation lead to a significant difference in ENSG00000196565 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and HBG2 expression is observed. Does this perturbation lead to a significant difference in HBG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1620,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of ENSG00000142945 is measured. Does this perturbation cause a significant change in ENSG00000142945 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of KIF2C is measured. Does this perturbation cause a significant change in KIF2C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of ENSG00000189171. Does this perturbation cause a significant change in ENSG00000189171 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of S100A13. Does this perturbation cause a significant change in S100A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in ENSG00000206172 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in HBA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of ENSG00000170180 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of GYPA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of ENSG00000162493. Does this perturbation cause a significant change in ENSG00000162493 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of PDPN. Does this perturbation cause a significant change in PDPN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of ENSG00000092067. Does perturbing CEBPE lead to a significant change in ENSG00000092067 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of CEBPE. Does perturbing CEBPE lead to a significant change in CEBPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3103,You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and ENSG00000135047 expression is observed. Does this perturbation lead to a significant difference in ENSG00000135047 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and CTSL expression is observed. Does this perturbation lead to a significant difference in CTSL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and ENSG00000169410 expression is quantified. Does this perturbation result in a significant change in ENSG00000169410 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and PTPN9 expression is quantified. Does this perturbation result in a significant change in PTPN9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and ENSG00000069535 expression is quantified. Does this perturbation result in a significant change in ENSG00000069535 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and MAOB expression is quantified. Does this perturbation result in a significant change in MAOB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of ENSG00000128016 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of ZFP36 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1713,You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and ENSG00000273706 expression is observed. Does this perturbation lead to a significant difference in ENSG00000273706 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and LHX1 expression is observed. Does this perturbation lead to a significant difference in LHX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
470,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of ENSG00000158517 is measured. Does this perturbation cause a significant change in ENSG00000158517 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of NCF1 is measured. Does this perturbation cause a significant change in NCF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
200,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of ENSG00000125144 is measured. Does this perturbation cause a significant change in ENSG00000125144 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of MT1G is measured. Does this perturbation cause a significant change in MT1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of ENSG00000163497 is measured. Determine whether ENSG00000163497 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of FEV is measured. Determine whether FEV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
593,You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and ENSG00000245532 expression is observed. Does this perturbation lead to a significant difference in ENSG00000245532 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and NEAT1 expression is observed. Does this perturbation lead to a significant difference in NEAT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3078,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2923,You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and ENSG00000120885 expression is observed. Does this perturbation lead to a significant difference in ENSG00000120885 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and CLU expression is observed. Does this perturbation lead to a significant difference in CLU expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in ENSG00000115053 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in NCL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of ENSG00000183019 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of MCEMP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and ENSG00000123473 expression is quantified. Does this perturbation result in a significant change in ENSG00000123473 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and STIL expression is quantified. Does this perturbation result in a significant change in STIL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2103,You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and ENSG00000164920 expression is observed. Does this perturbation lead to a significant difference in ENSG00000164920 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and OSR2 expression is observed. Does this perturbation lead to a significant difference in OSR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1348,"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor ENSG00000148180 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000148180 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor GSN expression. Decide whether this perturbation leads to a significant alteration in GSN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and ENSG00000196565 expression is measured. Determine whether ENSG00000196565 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and HBG2 expression is measured. Determine whether HBG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of ENSG00000100097. Does this perturbation cause a significant change in ENSG00000100097 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of LGALS1. Does this perturbation cause a significant change in LGALS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3038,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor ENSG00000130303 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130303 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor BST2 expression. Decide whether this perturbation leads to a significant alteration in BST2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and ENSG00000168140 expression is quantified. Does this perturbation result in a significant change in ENSG00000168140 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and VASN expression is quantified. Does this perturbation result in a significant change in VASN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2870,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of ENSG00000184009 is measured. Does this perturbation cause a significant change in ENSG00000184009 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of ACTG1 is measured. Does this perturbation cause a significant change in ACTG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and ENSG00000187997 expression is quantified. Does this perturbation result in a significant change in ENSG00000187997 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and C17orf99 expression is quantified. Does this perturbation result in a significant change in C17orf99 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2868,"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor ENSG00000075624 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000075624 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor ACTB expression. Decide whether this perturbation leads to a significant alteration in ACTB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and ENSG00000203989 expression is measured. Determine whether ENSG00000203989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and RHOXF2BB expression is measured. Determine whether RHOXF2BB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
193,You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and ENSG00000111057 expression is observed. Does this perturbation lead to a significant difference in ENSG00000111057 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and KRT18 expression is observed. Does this perturbation lead to a significant difference in KRT18 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2408,"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor ENSG00000237330 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000237330 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor RNF223 expression. Decide whether this perturbation leads to a significant alteration in RNF223 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and ENSG00000069482 expression is measured. Determine whether ENSG00000069482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and GAL expression is measured. Determine whether GAL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of ENSG00000157557. Does this perturbation cause a significant change in ENSG00000157557 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of ETS2. Does this perturbation cause a significant change in ETS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of ENSG00000103241 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of FOXF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of ENSG00000185198 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of ENSG00000117091 is measured. Determine whether ENSG00000117091 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of CD48 is measured. Determine whether CD48 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1603,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and ENSG00000186185 expression is observed. Does this perturbation lead to a significant difference in ENSG00000186185 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and KIF18B expression is observed. Does this perturbation lead to a significant difference in KIF18B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and ENSG00000118515 expression is quantified. Does this perturbation result in a significant change in ENSG00000118515 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and SGK1 expression is quantified. Does this perturbation result in a significant change in SGK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of ENSG00000184697. Does perturbing CLDN6 lead to a significant change in ENSG00000184697 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of CLDN6. Does perturbing CLDN6 lead to a significant change in CLDN6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of ENSG00000130656. Does perturbing ZBTB25 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of HBZ. Does perturbing ZBTB25 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2540,"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of ENSG00000166501 is measured. Does this perturbation cause a significant change in ENSG00000166501 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of PRKCB is measured. Does this perturbation cause a significant change in PRKCB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and ENSG00000143162 expression is measured. Determine whether ENSG00000143162 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and CREG1 expression is measured. Determine whether CREG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and ENSG00000030110 expression is quantified. Does this perturbation result in a significant change in ENSG00000030110 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and BAK1 expression is quantified. Does this perturbation result in a significant change in BAK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1278,"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor ENSG00000196188 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000196188 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor CTSE expression. Decide whether this perturbation leads to a significant alteration in CTSE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2788,"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor ENSG00000121068 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000121068 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor TBX2 expression. Decide whether this perturbation leads to a significant alteration in TBX2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
138,"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor ENSG00000030110 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000030110 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor BAK1 expression. Decide whether this perturbation leads to a significant alteration in BAK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of ENSG00000204472 is measured. Determine whether ENSG00000204472 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of AIF1 is measured. Determine whether AIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and ENSG00000189171 expression is quantified. Does this perturbation result in a significant change in ENSG00000189171 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and S100A13 expression is quantified. Does this perturbation result in a significant change in S100A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and ENSG00000206172 expression is quantified. Does this perturbation result in a significant change in ENSG00000206172 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and HBA1 expression is quantified. Does this perturbation result in a significant change in HBA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of ENSG00000163520. Does this perturbation cause a significant change in ENSG00000163520 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of FBLN2. Does this perturbation cause a significant change in FBLN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1258,"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor ENSG00000185198 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000185198 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and ENSG00000101200 expression is measured. Determine whether ENSG00000101200 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and AVP expression is measured. Determine whether AVP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2310,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of ENSG00000106991 is measured. Does this perturbation cause a significant change in ENSG00000106991 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of ENG is measured. Does this perturbation cause a significant change in ENG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of ENSG00000129757 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of CDKN1C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2843,You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of ENSG00000227053 is measured. Determine whether ENSG00000227053 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of RP11-395B7.4 is measured. Determine whether RP11-395B7.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
47,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of ENSG00000185198 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and ENSG00000135111 expression is measured. Determine whether ENSG00000135111 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and TBX3 expression is measured. Determine whether TBX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of ENSG00000204472 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of AIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of ENSG00000119535. Does this perturbation cause a significant change in ENSG00000119535 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of CSF3R. Does this perturbation cause a significant change in CSF3R expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of ENSG00000125144 is measured. Determine whether ENSG00000125144 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of MT1G is measured. Determine whether MT1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in ENSG00000135047 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in CTSL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and ENSG00000163520 expression is measured. Determine whether ENSG00000163520 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and FBLN2 expression is measured. Determine whether FBLN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of ENSG00000116871. Does this perturbation cause a significant change in ENSG00000116871 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of MAP7D1. Does this perturbation cause a significant change in MAP7D1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
79,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and ENSG00000113369 expression is measured. Determine whether ENSG00000113369 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and ARRDC3 expression is measured. Determine whether ARRDC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1673,You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and ENSG00000105610 expression is observed. Does this perturbation lead to a significant difference in ENSG00000105610 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and KLF1 expression is observed. Does this perturbation lead to a significant difference in KLF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of ENSG00000115053 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of NCL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of ENSG00000159399 is measured. Determine whether ENSG00000159399 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of HK2 is measured. Determine whether HK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2328,"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor ENSG00000182871 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000182871 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor COL18A1 expression. Decide whether this perturbation leads to a significant alteration in COL18A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2348,"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor ENSG00000169410 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169410 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor PTPN9 expression. Decide whether this perturbation leads to a significant alteration in PTPN9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of ENSG00000237330. Does perturbing RREB1 lead to a significant change in ENSG00000237330 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of RNF223. Does perturbing RREB1 lead to a significant change in RNF223 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and ENSG00000162878 expression is measured. Determine whether ENSG00000162878 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and PKDCC expression is measured. Determine whether PKDCC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and ENSG00000268621 expression is quantified. Does this perturbation result in a significant change in ENSG00000268621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ENSG00000099625 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of C19orf26 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of ENSG00000109099 is measured. Determine whether ENSG00000109099 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of PMP22 is measured. Determine whether PMP22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of ENSG00000185198. Does perturbing PTPN9 lead to a significant change in ENSG00000185198 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of PRSS57. Does perturbing PTPN9 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
273,You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and ENSG00000130303 expression is quantified. Does this perturbation result in a significant change in ENSG00000130303 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and BST2 expression is quantified. Does this perturbation result in a significant change in BST2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1173,You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and ENSG00000070214 expression is observed. Does this perturbation lead to a significant difference in ENSG00000070214 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and SLC44A1 expression is observed. Does this perturbation lead to a significant difference in SLC44A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and ENSG00000079102 expression is quantified. Does this perturbation result in a significant change in ENSG00000079102 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and RUNX1T1 expression is quantified. Does this perturbation result in a significant change in RUNX1T1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3113,You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and ENSG00000268621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000268621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1403,You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1658,"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor ENSG00000141744 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000141744 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor PNMT expression. Decide whether this perturbation leads to a significant alteration in PNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of ENSG00000260793. Does perturbing PLK4 lead to a significant change in ENSG00000260793 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of RP5-882C2.2. Does perturbing PLK4 lead to a significant change in RP5-882C2.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2463,You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and ENSG00000206172 expression is observed. Does this perturbation lead to a significant difference in ENSG00000206172 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and HBA1 expression is observed. Does this perturbation lead to a significant difference in HBA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of ENSG00000106991 is measured. Determine whether ENSG00000106991 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of ENG is measured. Determine whether ENG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of ENSG00000118777. Does perturbing ZBTB1 lead to a significant change in ENSG00000118777 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of ABCG2. Does perturbing ZBTB1 lead to a significant change in ABCG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and ENSG00000158517 expression is measured. Determine whether ENSG00000158517 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and NCF1 expression is measured. Determine whether NCF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of ENSG00000118058 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of KMT2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of ENSG00000268621. Does this perturbation cause a significant change in ENSG00000268621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1743,You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and ENSG00000104903 expression is observed. Does this perturbation lead to a significant difference in ENSG00000104903 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and LYL1 expression is observed. Does this perturbation lead to a significant difference in LYL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of ENSG00000227053. Does perturbing ZNF318 lead to a significant change in ENSG00000227053 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of RP11-395B7.4. Does perturbing ZNF318 lead to a significant change in RP11-395B7.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of ENSG00000130656. Does perturbing MAP4K5 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of HBZ. Does perturbing MAP4K5 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and ENSG00000130303 expression is measured. Determine whether ENSG00000130303 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and BST2 expression is measured. Determine whether BST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of ENSG00000117139 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of KDM5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
288,"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor ENSG00000102804 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000102804 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor TSC22D1 expression. Decide whether this perturbation leads to a significant alteration in TSC22D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of ENSG00000166501 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of PRKCB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of ENSG00000170689. Does perturbing HOXB9 lead to a significant change in ENSG00000170689 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of HOXB9. Does perturbing HOXB9 lead to a significant change in HOXB9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of ENSG00000105939. Does perturbing ZC3HAV1 lead to a significant change in ENSG00000105939 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of ZC3HAV1. Does perturbing ZC3HAV1 lead to a significant change in ZC3HAV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in ENSG00000159556 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in ISL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2228,"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor ENSG00000166450 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000166450 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor PRTG expression. Decide whether this perturbation leads to a significant alteration in PRTG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of ENSG00000206172. Does perturbing IKZF3 lead to a significant change in ENSG00000206172 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of HBA1. Does perturbing IKZF3 lead to a significant change in HBA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2013,You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and ENSG00000115738 expression is observed. Does this perturbation lead to a significant difference in ENSG00000115738 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and ID2 expression is observed. Does this perturbation lead to a significant difference in ID2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1110,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of ENSG00000183770 is measured. Does this perturbation cause a significant change in ENSG00000183770 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of FOXL2 is measured. Does this perturbation cause a significant change in FOXL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of ENSG00000102804 is measured. Determine whether ENSG00000102804 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of TSC22D1 is measured. Determine whether TSC22D1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of ENSG00000127831. Does perturbing LYL1 lead to a significant change in ENSG00000127831 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of VIL1. Does perturbing LYL1 lead to a significant change in VIL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of ENSG00000141744. Does perturbing KLF1 lead to a significant change in ENSG00000141744 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of PNMT. Does perturbing KLF1 lead to a significant change in PNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in ENSG00000197766 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in CFD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of ENSG00000206172. Does perturbing S1PR2 lead to a significant change in ENSG00000206172 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of HBA1. Does perturbing S1PR2 lead to a significant change in HBA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of ENSG00000185198. Does this perturbation cause a significant change in ENSG00000185198 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1568,"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor ENSG00000143674 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143674 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor KIAA1804 expression. Decide whether this perturbation leads to a significant alteration in KIAA1804 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in ENSG00000129757 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in CDKN1C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of ENSG00000177606. Does perturbing KIAA1804 lead to a significant change in ENSG00000177606 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of JUN. Does perturbing KIAA1804 lead to a significant change in JUN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of ENSG00000108821 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of COL1A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of ENSG00000188536 is measured. Determine whether ENSG00000188536 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of HBA2 is measured. Determine whether HBA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
49,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and ENSG00000185198 expression is measured. Determine whether ENSG00000185198 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
708,"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor ENSG00000256713 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000256713 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor PGA5 expression. Decide whether this perturbation leads to a significant alteration in PGA5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of ENSG00000090382. Does perturbing FOXA3 lead to a significant change in ENSG00000090382 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of LYZ. Does perturbing FOXA3 lead to a significant change in LYZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of ENSG00000129514. Does perturbing FOXA1 lead to a significant change in ENSG00000129514 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of FOXA1. Does perturbing FOXA1 lead to a significant change in FOXA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of ENSG00000206172. Does this perturbation cause a significant change in ENSG00000206172 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of HBA1. Does this perturbation cause a significant change in HBA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and ENSG00000129514 expression is measured. Determine whether ENSG00000129514 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and FOXA1 expression is measured. Determine whether FOXA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and ENSG00000159388 expression is measured. Determine whether ENSG00000159388 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and BTG2 expression is measured. Determine whether BTG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in ENSG00000002586 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in CD99 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
530,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of ENSG00000204482 is measured. Does this perturbation cause a significant change in ENSG00000204482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of ENSG00000237330 is measured. Determine whether ENSG00000237330 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of RNF223 is measured. Determine whether RNF223 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of ENSG00000185198 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in ENSG00000111057 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in KRT18 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and ENSG00000070087 expression is quantified. Does this perturbation result in a significant change in ENSG00000070087 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and PFN2 expression is quantified. Does this perturbation result in a significant change in PFN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of ENSG00000158578. Does perturbing IKZF3 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of ALAS2. Does perturbing IKZF3 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and ENSG00000243449 expression is quantified. Does this perturbation result in a significant change in ENSG00000243449 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and C4orf48 expression is quantified. Does this perturbation result in a significant change in C4orf48 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of ENSG00000143674. Does this perturbation cause a significant change in ENSG00000143674 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of KIAA1804. Does this perturbation cause a significant change in KIAA1804 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of ENSG00000143369 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of ECM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
508,"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor ENSG00000070087 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000070087 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor PFN2 expression. Decide whether this perturbation leads to a significant alteration in PFN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of ENSG00000142669. Does perturbing CSRNP1 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of SH3BGRL3. Does perturbing CSRNP1 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in ENSG00000143401 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in ANP32E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
780,"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of ENSG00000144655 is measured. Does this perturbation cause a significant change in ENSG00000144655 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of CSRNP1 is measured. Does this perturbation cause a significant change in CSRNP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
220,"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of ENSG00000135409 is measured. Does this perturbation cause a significant change in ENSG00000135409 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of AMHR2 is measured. Does this perturbation cause a significant change in AMHR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and ENSG00000157557 expression is measured. Determine whether ENSG00000157557 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and ETS2 expression is measured. Determine whether ETS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of ENSG00000256713. Does perturbing CNNM4 lead to a significant change in ENSG00000256713 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of PGA5. Does perturbing CNNM4 lead to a significant change in PGA5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and ENSG00000153094 expression is quantified. Does this perturbation result in a significant change in ENSG00000153094 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and BCL2L11 expression is quantified. Does this perturbation result in a significant change in BCL2L11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in ENSG00000105223 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in PLD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of ENSG00000070087. Does this perturbation cause a significant change in ENSG00000070087 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of PFN2. Does this perturbation cause a significant change in PFN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and ENSG00000064886 expression is measured. Determine whether ENSG00000064886 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and CHI3L2 expression is measured. Determine whether CHI3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of ENSG00000030110 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of BAK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and ENSG00000205277 expression is quantified. Does this perturbation result in a significant change in ENSG00000205277 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and MUC12 expression is quantified. Does this perturbation result in a significant change in MUC12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1073,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and ENSG00000163497 expression is quantified. Does this perturbation result in a significant change in ENSG00000163497 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and FEV expression is quantified. Does this perturbation result in a significant change in FEV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of ENSG00000160185. Does perturbing UBASH3A lead to a significant change in ENSG00000160185 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of UBASH3A. Does perturbing UBASH3A lead to a significant change in UBASH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in ENSG00000163499 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in CRYBA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3138,"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor ENSG00000205277 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000205277 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor MUC12 expression. Decide whether this perturbation leads to a significant alteration in MUC12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of ENSG00000158578. Does perturbing CBL lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of ALAS2. Does perturbing CBL lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and ENSG00000188483 expression is measured. Determine whether ENSG00000188483 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and IER5L expression is measured. Determine whether IER5L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of ENSG00000258274. Does this perturbation cause a significant change in ENSG00000258274 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of RP11-887P2.5. Does this perturbation cause a significant change in RP11-887P2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of ENSG00000119535 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of CSF3R indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
450,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of ENSG00000204482 is measured. Does this perturbation cause a significant change in ENSG00000204482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of ENSG00000268621. Does this perturbation cause a significant change in ENSG00000268621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and ENSG00000204482 expression is quantified. Does this perturbation result in a significant change in ENSG00000204482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of ENSG00000204482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1838,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor ENSG00000108984 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000108984 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor MAP2K6 expression. Decide whether this perturbation leads to a significant alteration in MAP2K6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of ENSG00000143162 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of CREG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in ENSG00000030110 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in BAK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and ENSG00000116871 expression is quantified. Does this perturbation result in a significant change in ENSG00000116871 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and MAP7D1 expression is quantified. Does this perturbation result in a significant change in MAP7D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of ENSG00000134294 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of SLC38A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of ENSG00000102804 is measured. Determine whether ENSG00000102804 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of TSC22D1 is measured. Determine whether TSC22D1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and ENSG00000177606 expression is quantified. Does this perturbation result in a significant change in ENSG00000177606 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and JUN expression is quantified. Does this perturbation result in a significant change in JUN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1888,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor ENSG00000135047 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000135047 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor CTSL expression. Decide whether this perturbation leads to a significant alteration in CTSL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of ENSG00000101200. Does this perturbation cause a significant change in ENSG00000101200 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of AVP. Does this perturbation cause a significant change in AVP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of ENSG00000185198. Does perturbing SAMD1 lead to a significant change in ENSG00000185198 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of PRSS57. Does perturbing SAMD1 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of ENSG00000153012 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of LGI2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of ENSG00000140545 is measured. Determine whether ENSG00000140545 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of MFGE8 is measured. Determine whether MFGE8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of ENSG00000163497. Does this perturbation cause a significant change in ENSG00000163497 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of FEV. Does this perturbation cause a significant change in FEV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and ENSG00000160185 expression is measured. Determine whether ENSG00000160185 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and UBASH3A expression is measured. Determine whether UBASH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2303,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and ENSG00000143369 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143369 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and ECM1 expression is observed. Does this perturbation lead to a significant difference in ECM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ENSG00000099625 expression is measured. Determine whether ENSG00000099625 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and C19orf26 expression is measured. Determine whether C19orf26 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of ENSG00000130656. Does perturbing CBL lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of HBZ. Does perturbing CBL lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in ENSG00000108821 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in COL1A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and ENSG00000077063 expression is quantified. Does this perturbation result in a significant change in ENSG00000077063 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and CTTNBP2 expression is quantified. Does this perturbation result in a significant change in CTTNBP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and ENSG00000075624 expression is quantified. Does this perturbation result in a significant change in ENSG00000075624 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and ACTB expression is quantified. Does this perturbation result in a significant change in ACTB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ENSG00000099625. Does perturbing C19orf26 lead to a significant change in ENSG00000099625 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of C19orf26. Does perturbing C19orf26 lead to a significant change in C19orf26 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2888,"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor ENSG00000101200 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000101200 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor AVP expression. Decide whether this perturbation leads to a significant alteration in AVP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3058,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in ENSG00000250361 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in GYPB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1128,"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor ENSG00000183770 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000183770 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor FOXL2 expression. Decide whether this perturbation leads to a significant alteration in FOXL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in ENSG00000085185 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in BCORL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2198,"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ENSG00000099625 expression is quantified. Does this perturbation result in a significant change in ENSG00000099625 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and C19orf26 expression is quantified. Does this perturbation result in a significant change in C19orf26 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1300,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of ENSG00000117091 is measured. Does this perturbation cause a significant change in ENSG00000117091 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of CD48 is measured. Does this perturbation cause a significant change in CD48 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
900,"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of ENSG00000005187 is measured. Does this perturbation cause a significant change in ENSG00000005187 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of ACSM3 is measured. Does this perturbation cause a significant change in ACSM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
82,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and ENSG00000115758 expression is quantified. Does this perturbation result in a significant change in ENSG00000115758 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and ODC1 expression is quantified. Does this perturbation result in a significant change in ODC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of ENSG00000184481. Does perturbing FOXO4 lead to a significant change in ENSG00000184481 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of FOXO4. Does perturbing FOXO4 lead to a significant change in FOXO4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
93,You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1008,"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor ENSG00000204482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000204482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of ENSG00000204482 is measured. Determine whether ENSG00000204482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of ENSG00000196188. Does this perturbation cause a significant change in ENSG00000196188 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of CTSE. Does this perturbation cause a significant change in CTSE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of ENSG00000172331 is measured. Determine whether ENSG00000172331 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of BPGM is measured. Determine whether BPGM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and ENSG00000189171 expression is measured. Determine whether ENSG00000189171 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in ENSG00000070214 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in SLC44A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in ENSG00000185198 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of ENSG00000258274 is measured. Determine whether ENSG00000258274 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of RP11-887P2.5 is measured. Determine whether RP11-887P2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of ENSG00000127831 is measured. Determine whether ENSG00000127831 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of VIL1 is measured. Determine whether VIL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1800,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of ENSG00000034152 is measured. Does this perturbation cause a significant change in ENSG00000034152 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of MAP2K3 is measured. Does this perturbation cause a significant change in MAP2K3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and ENSG00000170689 expression is quantified. Does this perturbation result in a significant change in ENSG00000170689 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and HOXB9 expression is quantified. Does this perturbation result in a significant change in HOXB9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of ENSG00000142945. Does this perturbation cause a significant change in ENSG00000142945 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of KIF2C. Does this perturbation cause a significant change in KIF2C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in ENSG00000127831 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in VIL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1198,"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor ENSG00000109099 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000109099 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor PMP22 expression. Decide whether this perturbation leads to a significant alteration in PMP22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of ENSG00000273706 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of LHX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of ENSG00000141753 is measured. Determine whether ENSG00000141753 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of IGFBP4 is measured. Determine whether IGFBP4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1750,"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of ENSG00000127831 is measured. Does this perturbation cause a significant change in ENSG00000127831 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of VIL1 is measured. Does this perturbation cause a significant change in VIL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
538,"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor ENSG00000204482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000204482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of ENSG00000064886 is measured. Determine whether ENSG00000064886 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of CHI3L2 is measured. Determine whether CHI3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and ENSG00000121900 expression is measured. Determine whether ENSG00000121900 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and TMEM54 expression is measured. Determine whether TMEM54 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1718,"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor ENSG00000273706 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000273706 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor LHX1 expression. Decide whether this perturbation leads to a significant alteration in LHX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of ENSG00000163513 is measured. Determine whether ENSG00000163513 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of TGFBR2 is measured. Determine whether TGFBR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in ENSG00000186185 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in KIF18B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1188,"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor ENSG00000163520 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163520 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor FBLN2 expression. Decide whether this perturbation leads to a significant alteration in FBLN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
910,"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of ENSG00000156030 is measured. Does this perturbation cause a significant change in ENSG00000156030 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of ELMSAN1 is measured. Does this perturbation cause a significant change in ELMSAN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and ENSG00000079102 expression is measured. Determine whether ENSG00000079102 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and RUNX1T1 expression is measured. Determine whether RUNX1T1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and ENSG00000185198 expression is measured. Determine whether ENSG00000185198 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
158,"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor ENSG00000153094 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000153094 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor BCL2L11 expression. Decide whether this perturbation leads to a significant alteration in BCL2L11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of ENSG00000166340 is measured. Determine whether ENSG00000166340 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of TPP1 is measured. Determine whether TPP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of ENSG00000258274. Does perturbing HOXC13 lead to a significant change in ENSG00000258274 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of RP11-887P2.5. Does perturbing HOXC13 lead to a significant change in RP11-887P2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of ENSG00000159388. Does this perturbation cause a significant change in ENSG00000159388 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of BTG2. Does this perturbation cause a significant change in BTG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of ENSG00000109099. Does perturbing GLB1L2 lead to a significant change in ENSG00000109099 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of PMP22. Does perturbing GLB1L2 lead to a significant change in PMP22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of ENSG00000130176. Does perturbing CNN1 lead to a significant change in ENSG00000130176 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of CNN1. Does perturbing CNN1 lead to a significant change in CNN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in ENSG00000142945 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in KIF2C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of ENSG00000069482. Does perturbing EGR1 lead to a significant change in ENSG00000069482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of GAL. Does perturbing EGR1 lead to a significant change in GAL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1333,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and ENSG00000170689 expression is observed. Does this perturbation lead to a significant difference in ENSG00000170689 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and HOXB9 expression is observed. Does this perturbation lead to a significant difference in HOXB9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2243,You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
673,You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and ENSG00000130176 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130176 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and CNN1 expression is observed. Does this perturbation lead to a significant difference in CNN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of ENSG00000169442. Does perturbing EGR1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of CD52. Does perturbing EGR1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1893,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
940,"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of ENSG00000204472 is measured. Does this perturbation cause a significant change in ENSG00000204472 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of AIF1 is measured. Does this perturbation cause a significant change in AIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of ENSG00000115255. Does perturbing CKS1B lead to a significant change in ENSG00000115255 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of REEP6. Does perturbing CKS1B lead to a significant change in REEP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
213,You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and ENSG00000172331 expression is observed. Does this perturbation lead to a significant difference in ENSG00000172331 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and BPGM expression is observed. Does this perturbation lead to a significant difference in BPGM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in ENSG00000104894 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in CD37 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of ENSG00000113594. Does this perturbation cause a significant change in ENSG00000113594 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of LIFR. Does this perturbation cause a significant change in LIFR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of ENSG00000127831 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of VIL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1240,"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of ENSG00000265972 is measured. Does this perturbation cause a significant change in ENSG00000265972 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in ENSG00000116871 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in MAP7D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
53,You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and ENSG00000160838 expression is observed. Does this perturbation lead to a significant difference in ENSG00000160838 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and LRRC71 expression is observed. Does this perturbation lead to a significant difference in LRRC71 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of ENSG00000115738. Does this perturbation cause a significant change in ENSG00000115738 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of ID2. Does this perturbation cause a significant change in ID2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
670,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of ENSG00000130176 is measured. Does this perturbation cause a significant change in ENSG00000130176 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of CNN1 is measured. Does this perturbation cause a significant change in CNN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
758,"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor ENSG00000139219 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000139219 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor COL2A1 expression. Decide whether this perturbation leads to a significant alteration in COL2A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of ENSG00000204482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of ENSG00000258274 is measured. Determine whether ENSG00000258274 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of RP11-887P2.5 is measured. Determine whether RP11-887P2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in ENSG00000279669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in RP11-717F1.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of ENSG00000196188 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of CTSE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1898,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
958,"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor ENSG00000157557 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000157557 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor ETS2 expression. Decide whether this perturbation leads to a significant alteration in ETS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2350,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of ENSG00000169410 is measured. Does this perturbation cause a significant change in ENSG00000169410 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of PTPN9 is measured. Does this perturbation cause a significant change in PTPN9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3128,"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor ENSG00000227053 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000227053 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor RP11-395B7.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-395B7.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1943,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and ENSG00000279576 expression is observed. Does this perturbation lead to a significant difference in ENSG00000279576 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and AP000769.1 expression is observed. Does this perturbation lead to a significant difference in AP000769.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of ENSG00000166450 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of PRTG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
258,"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ENSG00000099625 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000099625 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor C19orf26 expression. Decide whether this perturbation leads to a significant alteration in C19orf26 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of ENSG00000090382 is measured. Determine whether ENSG00000090382 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of LYZ is measured. Determine whether LYZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in ENSG00000116871 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in MAP7D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in ENSG00000170689 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in HOXB9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of ENSG00000130656. Does perturbing PTPN1 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of HBZ. Does perturbing PTPN1 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ENSG00000099625 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in C19orf26 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and ENSG00000277268 expression is measured. Determine whether ENSG00000277268 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and RP11-445F12.1 expression is measured. Determine whether RP11-445F12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
800,"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of ENSG00000100097 is measured. Does this perturbation cause a significant change in ENSG00000100097 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of LGALS1 is measured. Does this perturbation cause a significant change in LGALS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and ENSG00000103241 expression is measured. Determine whether ENSG00000103241 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and FOXF1 expression is measured. Determine whether FOXF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and ENSG00000258274 expression is measured. Determine whether ENSG00000258274 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and RP11-887P2.5 expression is measured. Determine whether RP11-887P2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2073,You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and ENSG00000189171 expression is observed. Does this perturbation lead to a significant difference in ENSG00000189171 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and S100A13 expression is observed. Does this perturbation lead to a significant difference in S100A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in ENSG00000159399 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in HK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of ENSG00000250361 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of GYPB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and ENSG00000119535 expression is measured. Determine whether ENSG00000119535 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and CSF3R expression is measured. Determine whether CSF3R exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of ENSG00000204482 is measured. Determine whether ENSG00000204482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of ENSG00000109099. Does this perturbation cause a significant change in ENSG00000109099 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of PMP22. Does this perturbation cause a significant change in PMP22 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of ENSG00000174498 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of IGDCC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
87,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of ENSG00000115758 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of ODC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1573,You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and ENSG00000005187 expression is observed. Does this perturbation lead to a significant difference in ENSG00000005187 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and ACSM3 expression is observed. Does this perturbation lead to a significant difference in ACSM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
643,You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and ENSG00000184697 expression is observed. Does this perturbation lead to a significant difference in ENSG00000184697 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and CLDN6 expression is observed. Does this perturbation lead to a significant difference in CLDN6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in ENSG00000105697 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in HAMP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
688,"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and ENSG00000204482 expression is quantified. Does this perturbation result in a significant change in ENSG00000204482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
25,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in ENSG00000077063 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in CTTNBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
41,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of ENSG00000185198. Does perturbing ARID1A lead to a significant change in ENSG00000185198 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of PRSS57. Does perturbing ARID1A lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2583,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and ENSG00000134294 expression is observed. Does this perturbation lead to a significant difference in ENSG00000134294 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and SLC38A2 expression is observed. Does this perturbation lead to a significant difference in SLC38A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2880,"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of ENSG00000101200 is measured. Does this perturbation cause a significant change in ENSG00000101200 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of AVP is measured. Does this perturbation cause a significant change in AVP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of ENSG00000034152 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of MAP2K3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1460,"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3043,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and ENSG00000189171 expression is observed. Does this perturbation lead to a significant difference in ENSG00000189171 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and S100A13 expression is observed. Does this perturbation lead to a significant difference in S100A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and ENSG00000189171 expression is measured. Determine whether ENSG00000189171 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of ENSG00000002586. Does this perturbation cause a significant change in ENSG00000002586 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of CD99. Does this perturbation cause a significant change in CD99 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and ENSG00000205542 expression is quantified. Does this perturbation result in a significant change in ENSG00000205542 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and TMSB4X expression is quantified. Does this perturbation result in a significant change in TMSB4X expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of ENSG00000142945. Does perturbing KIF2C lead to a significant change in ENSG00000142945 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of KIF2C. Does perturbing KIF2C lead to a significant change in KIF2C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and ENSG00000184697 expression is measured. Determine whether ENSG00000184697 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and CLDN6 expression is measured. Determine whether CLDN6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of ENSG00000141744 is measured. Determine whether ENSG00000141744 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of PNMT is measured. Determine whether PNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and ENSG00000196517 expression is quantified. Does this perturbation result in a significant change in ENSG00000196517 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and SLC6A9 expression is quantified. Does this perturbation result in a significant change in SLC6A9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of ENSG00000163520 is measured. Determine whether ENSG00000163520 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of FBLN2 is measured. Determine whether FBLN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of ENSG00000135111 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of TBX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and ENSG00000206172 expression is quantified. Does this perturbation result in a significant change in ENSG00000206172 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and HBA1 expression is quantified. Does this perturbation result in a significant change in HBA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1740,"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of ENSG00000104903 is measured. Does this perturbation cause a significant change in ENSG00000104903 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of LYL1 is measured. Does this perturbation cause a significant change in LYL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of ENSG00000153094 is measured. Determine whether ENSG00000153094 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of BCL2L11 is measured. Determine whether BCL2L11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and ENSG00000149516 expression is quantified. Does this perturbation result in a significant change in ENSG00000149516 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and MS4A3 expression is quantified. Does this perturbation result in a significant change in MS4A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and ENSG00000164920 expression is measured. Determine whether ENSG00000164920 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and OSR2 expression is measured. Determine whether OSR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of ENSG00000213934 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of HBG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in ENSG00000069011 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in PITX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3023,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and ENSG00000070214 expression is observed. Does this perturbation lead to a significant difference in ENSG00000070214 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and SLC44A1 expression is observed. Does this perturbation lead to a significant difference in SLC44A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1550,"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of ENSG00000159388 is measured. Does this perturbation cause a significant change in ENSG00000159388 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of BTG2 is measured. Does this perturbation cause a significant change in BTG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and ENSG00000135047 expression is measured. Determine whether ENSG00000135047 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and CTSL expression is measured. Determine whether CTSL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of ENSG00000124762. Does perturbing CDKN1A lead to a significant change in ENSG00000124762 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of CDKN1A. Does perturbing CDKN1A lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in ENSG00000170689 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in HOXB9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in ENSG00000272211 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in RP11-347P5.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in ENSG00000069482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in GAL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and ENSG00000101200 expression is quantified. Does this perturbation result in a significant change in ENSG00000101200 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and AVP expression is quantified. Does this perturbation result in a significant change in AVP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and ENSG00000166450 expression is quantified. Does this perturbation result in a significant change in ENSG00000166450 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and PRTG expression is quantified. Does this perturbation result in a significant change in PRTG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of ENSG00000247516. Does perturbing ZBTB25 lead to a significant change in ENSG00000247516 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of MIR4458HG. Does perturbing ZBTB25 lead to a significant change in MIR4458HG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and ENSG00000163513 expression is quantified. Does this perturbation result in a significant change in ENSG00000163513 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and TGFBR2 expression is quantified. Does this perturbation result in a significant change in TGFBR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of ENSG00000162493 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of PDPN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and ENSG00000070214 expression is measured. Determine whether ENSG00000070214 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and SLC44A1 expression is measured. Determine whether SLC44A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2853,You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and ENSG00000205542 expression is observed. Does this perturbation lead to a significant difference in ENSG00000205542 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and TMSB4X expression is observed. Does this perturbation lead to a significant difference in TMSB4X expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of ENSG00000130176 is measured. Determine whether ENSG00000130176 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of CNN1 is measured. Determine whether CNN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of ENSG00000103241. Does this perturbation cause a significant change in ENSG00000103241 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of FOXF1. Does this perturbation cause a significant change in FOXF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in ENSG00000129514 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in FOXA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and ENSG00000279669 expression is measured. Determine whether ENSG00000279669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and RP11-717F1.1 expression is measured. Determine whether RP11-717F1.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of ENSG00000115738 is measured. Determine whether ENSG00000115738 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of ID2 is measured. Determine whether ID2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
153,You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and ENSG00000153094 expression is observed. Does this perturbation lead to a significant difference in ENSG00000153094 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and BCL2L11 expression is observed. Does this perturbation lead to a significant difference in BCL2L11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in ENSG00000166450 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in PRTG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of ENSG00000124762. Does perturbing CDKN1A lead to a significant change in ENSG00000124762 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of CDKN1A. Does perturbing CDKN1A lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2848,"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and ENSG00000069482 expression is measured. Determine whether ENSG00000069482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and GAL expression is measured. Determine whether GAL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of ENSG00000188483 is measured. Determine whether ENSG00000188483 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of IER5L is measured. Determine whether IER5L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in ENSG00000203989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in RHOXF2BB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in ENSG00000247516 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in MIR4458HG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of ENSG00000115844 is measured. Determine whether ENSG00000115844 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of DLX2 is measured. Determine whether DLX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and ENSG00000106991 expression is quantified. Does this perturbation result in a significant change in ENSG00000106991 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and ENG expression is quantified. Does this perturbation result in a significant change in ENG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in ENSG00000240065 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in PSMB9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1758,"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor ENSG00000127831 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000127831 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor VIL1 expression. Decide whether this perturbation leads to a significant alteration in VIL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
97,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of ENSG00000177606 is measured. Determine whether ENSG00000177606 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of JUN is measured. Determine whether JUN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
310,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of ENSG00000196565 is measured. Does this perturbation cause a significant change in ENSG00000196565 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of HBG2 is measured. Does this perturbation cause a significant change in HBG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
440,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of ENSG00000129757 is measured. Does this perturbation cause a significant change in ENSG00000129757 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of CDKN1C is measured. Does this perturbation cause a significant change in CDKN1C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in ENSG00000119535 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in CSF3R expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1018,"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of ENSG00000157557. Does this perturbation cause a significant change in ENSG00000157557 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of ETS2. Does this perturbation cause a significant change in ETS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and ENSG00000071967 expression is quantified. Does this perturbation result in a significant change in ENSG00000071967 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and CYBRD1 expression is quantified. Does this perturbation result in a significant change in CYBRD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and ENSG00000163520 expression is quantified. Does this perturbation result in a significant change in ENSG00000163520 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and FBLN2 expression is quantified. Does this perturbation result in a significant change in FBLN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and ENSG00000030110 expression is measured. Determine whether ENSG00000030110 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and BAK1 expression is measured. Determine whether BAK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and ENSG00000260793 expression is measured. Determine whether ENSG00000260793 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and RP5-882C2.2 expression is measured. Determine whether RP5-882C2.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
740,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of ENSG00000279576. Does perturbing MAP7D1 lead to a significant change in ENSG00000279576 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of AP000769.1. Does perturbing MAP7D1 lead to a significant change in AP000769.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of ENSG00000170689 is measured. Determine whether ENSG00000170689 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of HOXB9 is measured. Determine whether HOXB9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1948,"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor ENSG00000279576 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000279576 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor AP000769.1 expression. Decide whether this perturbation leads to a significant alteration in AP000769.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of ENSG00000135409 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of AMHR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and ENSG00000164920 expression is measured. Determine whether ENSG00000164920 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and OSR2 expression is measured. Determine whether OSR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2363,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and ENSG00000185198 expression is observed. Does this perturbation lead to a significant difference in ENSG00000185198 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of ENSG00000133317 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of LGALS12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1913,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and ENSG00000169413 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169413 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and RNASE6 expression is observed. Does this perturbation lead to a significant difference in RNASE6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of ENSG00000247516 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of MIR4458HG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and ENSG00000162493 expression is measured. Determine whether ENSG00000162493 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and PDPN expression is measured. Determine whether PDPN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
88,"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor ENSG00000115758 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000115758 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor ODC1 expression. Decide whether this perturbation leads to a significant alteration in ODC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
48,"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor ENSG00000185198 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000185198 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and ENSG00000075624 expression is measured. Determine whether ENSG00000075624 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and ACTB expression is measured. Determine whether ACTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of ENSG00000189171 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of S100A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of ENSG00000170689. Does perturbing HOXB9 lead to a significant change in ENSG00000170689 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of HOXB9. Does perturbing HOXB9 lead to a significant change in HOXB9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
51,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of ENSG00000160838. Does perturbing ARID1A lead to a significant change in ENSG00000160838 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of LRRC71. Does perturbing ARID1A lead to a significant change in LRRC71 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2253,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of ENSG00000064886. Does this perturbation cause a significant change in ENSG00000064886 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of CHI3L2. Does this perturbation cause a significant change in CHI3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2100,"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of ENSG00000164920 is measured. Does this perturbation cause a significant change in ENSG00000164920 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of OSR2 is measured. Does this perturbation cause a significant change in OSR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
20,"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of ENSG00000077063 is measured. Does this perturbation cause a significant change in ENSG00000077063 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of CTTNBP2 is measured. Does this perturbation cause a significant change in CTTNBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of ENSG00000142945 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of KIF2C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2653,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in ENSG00000163531 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in NFASC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of ENSG00000265972 is measured. Determine whether ENSG00000265972 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in ENSG00000106991 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in ENG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in ENSG00000205542 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in TMSB4X expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of ENSG00000185198 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of ENSG00000116871 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of MAP7D1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of ENSG00000168140 is measured. Determine whether ENSG00000168140 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of VASN is measured. Determine whether VASN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
928,"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor ENSG00000005187 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000005187 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor ACSM3 expression. Decide whether this perturbation leads to a significant alteration in ACSM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of ENSG00000172331. Does perturbing BPGM lead to a significant change in ENSG00000172331 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of BPGM. Does perturbing BPGM lead to a significant change in BPGM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of ENSG00000231312. Does perturbing MAP4K3 lead to a significant change in ENSG00000231312 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of AC007246.3. Does perturbing MAP4K3 lead to a significant change in AC007246.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of ENSG00000135047 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of CTSL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of ENSG00000256713 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of PGA5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and ENSG00000119535 expression is quantified. Does this perturbation result in a significant change in ENSG00000119535 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and CSF3R expression is quantified. Does this perturbation result in a significant change in CSF3R expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
29,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and ENSG00000077063 expression is measured. Determine whether ENSG00000077063 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and CTTNBP2 expression is measured. Determine whether CTTNBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and ENSG00000069535 expression is measured. Determine whether ENSG00000069535 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and MAOB expression is measured. Determine whether MAOB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of ENSG00000105610 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of KLF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and ENSG00000183019 expression is quantified. Does this perturbation result in a significant change in ENSG00000183019 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and MCEMP1 expression is quantified. Does this perturbation result in a significant change in MCEMP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and ENSG00000130176 expression is measured. Determine whether ENSG00000130176 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and CNN1 expression is measured. Determine whether CNN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1080,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of ENSG00000103241 is measured. Does this perturbation cause a significant change in ENSG00000103241 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of FOXF1 is measured. Does this perturbation cause a significant change in FOXF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of ENSG00000085185. Does this perturbation cause a significant change in ENSG00000085185 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of BCORL1. Does this perturbation cause a significant change in BCORL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and ENSG00000111057 expression is quantified. Does this perturbation result in a significant change in ENSG00000111057 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and KRT18 expression is quantified. Does this perturbation result in a significant change in KRT18 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
210,"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of ENSG00000172331 is measured. Does this perturbation cause a significant change in ENSG00000172331 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of BPGM is measured. Does this perturbation cause a significant change in BPGM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
183,You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and ENSG00000085185 expression is observed. Does this perturbation lead to a significant difference in ENSG00000085185 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and BCORL1 expression is observed. Does this perturbation lead to a significant difference in BCORL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of ENSG00000204482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of ENSG00000279669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of RP11-717F1.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
978,"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor ENSG00000163497 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163497 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor FEV expression. Decide whether this perturbation leads to a significant alteration in FEV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2638,"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor ENSG00000004939 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000004939 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor SLC4A1 expression. Decide whether this perturbation leads to a significant alteration in SLC4A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2530,"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of ENSG00000170542 is measured. Does this perturbation cause a significant change in ENSG00000170542 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of SERPINB9 is measured. Does this perturbation cause a significant change in SERPINB9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
423,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
64,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of ENSG00000268621. Does this perturbation cause a significant change in ENSG00000268621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and ENSG00000247516 expression is quantified. Does this perturbation result in a significant change in ENSG00000247516 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and MIR4458HG expression is quantified. Does this perturbation result in a significant change in MIR4458HG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of ENSG00000118515 is measured. Determine whether ENSG00000118515 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of SGK1 is measured. Determine whether SGK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in ENSG00000069482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in GAL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2148,"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor ENSG00000260793 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000260793 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor RP5-882C2.2 expression. Decide whether this perturbation leads to a significant alteration in RP5-882C2.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2593,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and ENSG00000268621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000268621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and ENSG00000255346 expression is measured. Determine whether ENSG00000255346 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and NOX5 expression is measured. Determine whether NOX5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of ENSG00000064886 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of CHI3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3123,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and ENSG00000227053 expression is observed. Does this perturbation lead to a significant difference in ENSG00000227053 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and RP11-395B7.4 expression is observed. Does this perturbation lead to a significant difference in RP11-395B7.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1063,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and ENSG00000170608 expression is observed. Does this perturbation lead to a significant difference in ENSG00000170608 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and FOXA3 expression is observed. Does this perturbation lead to a significant difference in FOXA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
3096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of ENSG00000105939 is measured. Determine whether ENSG00000105939 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of ZC3HAV1 is measured. Determine whether ZC3HAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of ENSG00000247516 is measured. Determine whether ENSG00000247516 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of MIR4458HG is measured. Determine whether MIR4458HG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of ENSG00000185198 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and ENSG00000119535 expression is measured. Determine whether ENSG00000119535 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and CSF3R expression is measured. Determine whether CSF3R exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
103,You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of ENSG00000128016 is measured. Determine whether ENSG00000128016 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of ZFP36 is measured. Determine whether ZFP36 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and ENSG00000154127 expression is measured. Determine whether ENSG00000154127 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and UBASH3B expression is measured. Determine whether UBASH3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and ENSG00000124762 expression is measured. Determine whether ENSG00000124762 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of ENSG00000184697. Does this perturbation cause a significant change in ENSG00000184697 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of CLDN6. Does this perturbation cause a significant change in CLDN6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of ENSG00000205542. Does this perturbation cause a significant change in ENSG00000205542 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of TMSB4X. Does this perturbation cause a significant change in TMSB4X expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in ENSG00000196565 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in HBG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2720,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of ENSG00000011600 is measured. Does this perturbation cause a significant change in ENSG00000011600 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of TYROBP is measured. Does this perturbation cause a significant change in TYROBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in ENSG00000162493 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in PDPN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and ENSG00000170689 expression is measured. Determine whether ENSG00000170689 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and HOXB9 expression is measured. Determine whether HOXB9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
893,You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and ENSG00000069482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000069482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and GAL expression is observed. Does this perturbation lead to a significant difference in GAL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in ENSG00000279576 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in AP000769.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and ENSG00000240065 expression is quantified. Does this perturbation result in a significant change in ENSG00000240065 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and PSMB9 expression is quantified. Does this perturbation result in a significant change in PSMB9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1218,"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor ENSG00000069011 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000069011 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor PITX1 expression. Decide whether this perturbation leads to a significant alteration in PITX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2673,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and ENSG00000279669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000279669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and RP11-717F1.1 expression is observed. Does this perturbation lead to a significant difference in RP11-717F1.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
57,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of ENSG00000160838 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of LRRC71 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of ENSG00000111057. Does perturbing BCORL1 lead to a significant change in ENSG00000111057 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of KRT18. Does perturbing BCORL1 lead to a significant change in KRT18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
140,"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of ENSG00000030110 is measured. Does this perturbation cause a significant change in ENSG00000030110 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of BAK1 is measured. Does this perturbation cause a significant change in BAK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
680,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of ENSG00000092067 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of CEBPE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of ENSG00000158578. Does perturbing SNAI1 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of ALAS2. Does perturbing SNAI1 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of ENSG00000075624. Does this perturbation cause a significant change in ENSG00000075624 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of ACTB. Does this perturbation cause a significant change in ACTB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
590,"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of ENSG00000245532 is measured. Does this perturbation cause a significant change in ENSG00000245532 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of NEAT1 is measured. Does this perturbation cause a significant change in NEAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and ENSG00000177606 expression is measured. Determine whether ENSG00000177606 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and JUN expression is measured. Determine whether JUN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1583,You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and ENSG00000177606 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177606 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and JUN expression is observed. Does this perturbation lead to a significant difference in JUN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of ENSG00000196565 is measured. Determine whether ENSG00000196565 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of HBG2 is measured. Determine whether HBG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of ENSG00000103241 is measured. Determine whether ENSG00000103241 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of FOXF1 is measured. Determine whether FOXF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
340,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in ENSG00000114315 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in HES1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and ENSG00000188536 expression is quantified. Does this perturbation result in a significant change in ENSG00000188536 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and HBA2 expression is quantified. Does this perturbation result in a significant change in HBA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
22,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and ENSG00000077063 expression is quantified. Does this perturbation result in a significant change in ENSG00000077063 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and CTTNBP2 expression is quantified. Does this perturbation result in a significant change in CTTNBP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
838,"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor ENSG00000026297 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000026297 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor RNASET2 expression. Decide whether this perturbation leads to a significant alteration in RNASET2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of ENSG00000140545. Does this perturbation cause a significant change in ENSG00000140545 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of MFGE8. Does this perturbation cause a significant change in MFGE8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3000,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of ENSG00000118777 is measured. Does this perturbation cause a significant change in ENSG00000118777 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of ABCG2 is measured. Does this perturbation cause a significant change in ABCG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."